Abstract: A fundus camera, which does not take time for adjustment of illumination light amount and focusing even if brightness of the fundus is different for each eye to be inspected, includes an illumination unit for illuminating the fundus of the eye to be inspected, a photometry unit for performing photometry of reflection light from the fundus illuminated by the illumination unit, an illumination light amount control unit for controlling a light amount of the illumination unit, a focus detection area determining unit for determining a focus detection area with respect to a fundus image taken by an image pickup unit, and a focus detection unit for detecting a focus position in the area determined by the focus detection area determining unit. The photometry unit calculates a photometry value of the focus detection area, and the illumination light amount is controlled based on the photometry value.

Abstract: The present invention relates to a method for measuring ocular scattering, comprising the steps of: sequentially projecting images from an extensive light source, corresponding to different visual angles, onto the retina; recording the output light in a camera or detector once it has passed through the eye twice; calculating the intensity at the center of each recorded image; calculating the PSF for each angle from the previous intensities; and calculating the average of the value of the PSF between the angles. The invention also relates to a system for carrying out said method. The invention can be used to measure the intensity of the scattered light in an objective manner.

Abstract: A vital signal measurement system including a plurality of terminals aims to facilitate synchronization of each terminal with respect to other terminals. Each of the plurality of terminals (102) is provided with a first vital signal sensor (201) for measuring a vital signal, a first memory (205) for storing a first data which is based on the vital signal, and a first radio communication unit (206) for communicating with other terminals by radio. The first data is applied with a sequence number corresponding to the first data and the number indicates an order in which the first data is acquired. A first terminal (102b) included in the plurality of terminals performs resetting of the sequence number triggered by the synchronous signal which is received by the first radio communication unit.

Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.

Abstract: A method, a computer program product and a computer-readable storage medium are disclosed for displaying signal values of a combined magnetic resonance positron emission tomography device. In at least one embodiment, the spatial correspondence of signal values, which result from a magnetic resonance measurement, and of signal values, which result from a positron emission tomography measurement, are used and the corresponding signal values are arranged in matrix form and displayed graphically as a multi-dimensional scatter plot.

Abstract: A multispectral nevoscope that uses specific wavelengths in the visible and infrared spectrum of electromagnetic radiation to transilluminate a skin-lesion or a biological tissue or specimen for imaging and maps multispectral 2-dimensional images into 3-dimensional virtual space for providing 3-D distributions of pre-defined parameters representing the characteristic properties (such as melanin, hemoglobin and deoxyhemoglobin, etc.) of a skin lesion. Methods are disclosed for analyzing and using the characteristic distributions of specific parameters for detection and management of skin-cancers, or characterization of a biological tissue or specimen.

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

Abstract: An imaging apparatus for diagnosis and a control method of an imaging apparatus for diagnosis are disclosed, which acquire line data represented by multiple luminance values in a radial direction from a rotation center position of an imaging core, which are derived by a rotation position and movement of the imaging core. Then, based on the acquired line data, an image of a two-dimensional space in which ? representing a rotation angle and z representing a position in a movement direction are set to two axes is generated and displayed.

Abstract: A method of multi-spectral opto-acoustic tomography (MSOT) imaging of a target tissue including a target tissue biomarker includes illuminating the target tissue with an illumination device emitting at least one pulsed illumination pattern at several illumination wavelengths, detecting pressure signals from the target tissue biomarker with a detector device, wherein the pressure signals being produced in the target tissue are in response to the illumination, and reconstructing a quantitative tomographic image of a distribution of the target tissue biomarker in the target tissue, wherein the pressure signals are analyzed using a photon propagation model which depends on an illuminating light fluence in the target tissue and on the illumination wavelengths, at least one spectral processing scheme, and an inversion scheme providing the tomographic image.

Abstract: An ultrasonic probe includes a light irradiating portion configured to radiate light for generating ultrasonic waves from a light absorber, an ultrasonic transducing portion configured to transduce the ultrasonic waves to an electric signal, and a light guide member configured to introduce light from a light source to the light irradiating portion. A light irradiating region of the light irradiating portion is included within an ultrasonic receiving region of the ultrasonic transducing portion.

Abstract: A dashboard centered around arrhythmia or atrial fibrillation tracking is provided. The dashboard includes a heart or cardiac health score that can be calculated in response to data from the user such as their ECG and other personal information and cardiac health influencing factors. The dashboard also provides to the user recommendations or goals, such as daily goals, for the user to meet and thereby improve their heart or cardiac health score. These goals and recommendations may be set by the user or a medical professional and routinely updated as his or her heart or cardiac health score improves or otherwise changes. The dashboard is generally displayed from an application provided on a smartphone or tablet computer of the user.

Abstract: A first oscillation circuit and a second oscillation circuit are connected to a first pressure sensor and a second pressure sensor, respectively, and oscillate based on the capacity values of the corresponding pressure sensors. The first oscillation circuit and the second oscillation circuit operate in response to instruction from a CPU. The one of the first oscillation circuit and the second oscillation circuit that has received an activation signal from the CPU outputs a signal having a frequency that corresponds to the capacity value of the corresponding pressure sensor. An adjustment circuit is connected to the first oscillation circuit and the second oscillation circuit, and allows one of the frequency signals to pass therethrough, outputting the signal to the CPU.

Abstract: A blood pressure information measurement device includes a main body, including an inflation pump and an exhaust valve, and a cuff, including an air bladder for pulse wave measurement and an air bladder for blood pressure value measurement. The air bladder for pulse wave measurement and the air bladder for blood pressure value measurement are wrapped around a proximal side and a distal side of the upper arm, respectively. A first piping portion connects the air bladder for blood pressure value measurement to the inflation pump and the exhaust valve. A second piping portion branching from the first piping portion connects the air bladder for pulse wave measurement to the first piping portion. The second piping portion includes a 2-port valve that switches between connecting and disconnecting the air bladder for pulse wave measurement and the first piping portion, and a pressure sensor for measuring a pulse wave.

Abstract: A software app for a mobile device is disclosed for alerting a custodian of a person to be protected of an emergency situation involving the person to be protected. The app includes software instructions for carrying out a method including: establishing a range of normal heart rates for the person using a heart rate monitor; detecting a heart rate for the person that is outside of the established range; activating at least one of a camera, a microphone, an accelerometer, and a location indicator on the mobile device carried by the person; establishing a wireless data connection between the mobile device and a communication network; and transmitting data to the custodian from the activated camera, microphone, accelerometer, or location indicator via the communication network. The app can notify a custodian of a medical or safety emergency as it is happening, giving that custodian the ability to immediately notify emergency personnel.

Abstract: The invention provides systems and methods for monitoring the wellbeing of a fetus by the non-invasive detection and analysis of fetal cardiac electrical activity data.

Abstract: In one example, a method includes determining a slope of a cardiac electrogram. The method may also include determining a threshold value based on a maximum of the slope of the cardiac electrogram. The method may further include identifying a last point of the cardiac electrogram before the slope of the cardiac electrogram crosses the threshold as one of an onset or an offset of a wave. In another example, the method further includes receiving an indication of local ventricular motion associated with a cardiac contraction, and determining an electromechanical delay between the identified onset and the local ventricular motion. Some examples include providing the electromechanical delay for configuration of cardiac resynchronization therapy.

Abstract: The present invention relates to a physiological recording electrode, a method, and apparatus for attaching the physiological electrode to a subject. The physiological electrode comprises a substrate having an upper and a lower surface, and at least one penetrator(s) protruding from the upper surface of the substrate. The penetrator(s) is capable of piercing through the stratum corneum or outer layer of the skin, and transmitting an electric potential from the lower layers of the epidermis through the penetrator(s) which can be measured, or detecting agents from the lower layers of the epidermis primarily the stratum germinativum layer. At least one epidermis stop may be provided resulting in the formation of detritus troughs interposed between adjacent penetrator(s) and epidermis stops. The physiological electrode is attached to a subject by means of the apparatus and method for attaching same. The present invention also includes a method of sensing biopotentials in the skin.

Abstract: A multi sensor module especially designed for use in sleep-study applications includes a PVDF film piezoelectric transducer enclosed between an upper layer of a single-sided adhesive tape strip and a lower layer of a double-sided adhesive tape strip. Also adhesively affixed to the upper single-sided adhesive tape strip, but not overlaid by the lower double-sided adhesive tape strip are first and second conductive electrodes. The combination sensor module is adapted to be adhesively affixed to the chest area of a person and further included in an extension of the PVDF strip that is adapted to overlay the suprasternal notch of a person for producing signals responsive to respiratory activity of the person.

Abstract: An EP catheter includes a tubular body having a proximal region, a neck region, and a distal portion predisposed into an in-plane dual loop (at least, approximately, more or less) configuration and including a plurality of diagnostic electrodes. In deflectable catheter forms, at least one activation wire extends through at least a portion of the proximal region of the catheter body and is adapted to deflect the distal portion up to approximately 180 degrees relative to the proximal region. The catheter can be operated manually by a clinician or via a clinician-surrogate such as a computer processor-controlled surgical system. In addition, a variety of localization, visualization, and/or orientation-specific elements can be incorporated into the devices described, depicted, and claimed herein (e.g., metallic coil members, active impedance emitting or receiving electrodes, fluoroscopically opaque materials, and the like).

Abstract: Transducer-based systems and methods may be configured to display a graphical representation of a transducer-based device, the graphical representation including graphical elements corresponding to transducers of the transducer-based device, and also including between graphical elements respectively associated with a set of the transducers and respectively associated with a region of space between the transducers of the transducer-based device. Selection of graphical elements and/or between graphical elements can cause activation of the set of transducers associated with the selected elements. Transducer activation characteristics, such as initiation time, activation duration, activation sequence, and energy delivery characteristics, can vary based on numerous factors. Visual characteristics of graphical elements and between graphical elements can change based on an activation-status of the corresponding transducers.

Abstract: This invention provides a system and method that improves the sensitivity and localization capabilities of Magnetic Particle Imaging (MPI) by using combinations of time-varying and static magnetic fields. Combinations of magnetic fields can be used to distribute the signals coming from the magnetic particles among the harmonics and other frequencies in specific ways to improve sensitivity and to provide localization information to speed up or improve the signal-to-noise ratio (SNR) of imaging and/or eliminate the need for saturation fields currently used in MPI. In various embodiments, coils can be provided to extend the sub-saturation region in which nanoparticles reside; to provide a static field offset to bring nanoparticles nearer to saturation; to introduce even and odd harmonics that can be observed; and/or to introduce combinations of frequencies for more-defined observation of signals from nanoparticles.

Abstract: A method for monitoring an intrabody region of a patient. The method comprises intercepting electromagnetic (EM) radiation from the intrabody region in a plurality of EM radiation sessions during a period of at least 6 hours, calculating a dielectric related change of the intrabody region by analyzing respective the intercepted EM radiation, detecting a physiological pattern according to said dielectric related change. and outputting a notification indicating the physiological pattern.

Abstract: Diagnostic apparatus includes a plurality of antennas, which are configured to be disposed at different, respective locations on a thorax of a living body so as to direct radio frequency (RF) electromagnetic waves from different, respective directions toward a heart in the body and to output RF signals responsively to the waves that are scattered from the heart. Processing circuitry is configured to process the RF signals over time so as to provide a multi-dimensional measurement of a movement of the heart.

Abstract: There is disclosed an apparatus for measuring biometric information having a hand rest, which can perform precise and comprehensive measurement by measuring biometric information about an examinee taking a more comfortable position. The apparatus for measuring the biometric information having the hand rest formed in a convex curvature shape to have an examinee's hand put thereon, to contact with an examinee's palm and fingers; and a measurement part provided in the hand rest to measure the examinee's biometric information.

Abstract: A method for producing multiple temporal frames of a time-resolved contrast enhanced magnetic resonance angiogram from a subject using an MR contrast agent by repeatedly applying RF pulses and sampling data in the corresponding image k-space along spiral trajectories that start at the k-space center and spiral outward toward the k-space edge.

Abstract: An apparatus for magnetic resonance imaging includes a magnet, a patient support, and a contoured quadrature coil. The contoured quadrature coil includes a ring coil and an angled butterfly coil. The angled butterfly coil may have a front outer section, an inner section, and a back outer section. The front outer section and the back outer section may be oriented diagonally from the plane of the ring coil such that a portion of the front outer section and/or the back outer section are disposed above the plane of the ring coil and a portion of the front outer section and/or the back outer section are disposed below the plane of the ring coil. Thus, the planes of the front and back outer sections may be angled with respect to each other, and the inner section may be substantially pyramidal and disposed along or below the plane of the ring coil.

Abstract: A joint of a patient is scanned using MRI apparatus, and images of the joint area are produced as a body part of the patient is moved into a particular position known to cause a problem in the joint. The patient may walk or run on a treadmill during the process, or the body part may be supported on a surface causing or allowing such movement.

Abstract: A Baby Monitoring Mat is provided having a top mesh layer, a bottom mesh layer, two flexible sheets, and an optical cable. The optical cable can be routed between the top mesh layer and the bottom mesh layer. The flexible sheets are also between the top mesh layer and the bottom mesh layer forming a sensing area. A light source is provided for feeding light from one side of the optical cable to a photodiode for detecting light attenuation at the other end of the optical cable. A processor receives signals from the light source and photodiode and the signals are processed to determine movements and breath counts. The signals are generated based on the light attenuation changes along the optical fiber cable detected by photodiode. A method for monitoring baby on a mat is also provided.

Abstract: Based on a capnometry signal, one or more breathing parameters of a subject are determined that require valid breaths by the subject to be distinguished from anatomical events that cause the CO2 content of gas at or near the airway of the subject to fluctuate. To improve the accuracy of one or more of these determinations, gas at or near the airway of the subject is diluted.

Abstract: Apparatus for generating an organ timing signal relating to an inspected organ within the body of a patient, including a medical positioning system, and a processor The medical positioning system includes at least one reference electromagnetic transducer placed at a reference location, at least one inner electromagnetic transducer attached to a surgical tool inserted in a blood vessel in the vicinity of the inspected organ, and a medical positioning system processor coupled with the transducers. The medical positioning system processor generates medical positioning system data sets, each of which includes a collection of three-dimensional position coordinate readings demonstrating the motion trajectory of the surgical tool over time, the processor generating the organ timing signal from the data sets by detecting and identifying periodic motion frequencies in the data sets, and filtering the periodic motion frequencies from the data sets.

Abstract: In a wearable motion assist device, a motion assist device for generating a motion pattern synchronized with a wearer while maintaining a certain phase difference between a motion of the wearer and a motion of the device, and a synchronization based control method for the device are provided. The motion assist device acquires a phase of torque generated by the wearer's motion, applies a value of the phase to a phase oscillator model as an input, performs arithmetic processing, and calculates target torque and a target angle of the device with the motion of the device synchronized with the wearer. It is possible to improve an assisting effect of the device by controlling the device based on the calculated values.

Abstract: Apparatuses, methods and systems for a user monitoring apparatus are disclosed. One embodiment of the user monitoring apparatus includes one or more magnetic sensors operative to sense magnetic fields applied to the user monitoring apparatus. Further, the user monitoring apparatus is operative to sense at least one biometric characteristic of a user of the user monitoring apparatus based upon the sensed magnetic field applied to the user monitoring apparatus.

Abstract: Disclosed herein is a fluid conductivity sensor that can be used to obtain in-vivo measurements of conductivity of biological fluid samples, for example, to determine osmolarity. The conductivity sensor can be disposed on a substrate that is at least partially embedded within a polymeric material of a body-mountable device. The conductivity sensor can include a frame having a trench formed therein that defines a fluid sample cell. First and second electrodes can be formed on sidewalls of the trench, such that the first and second electrodes are on opposite sides of the fluid sample cell. A controller in the body-mountable device can operate the sensor by applying a voltage to the electrodes and measuring a current through a fluid occupying the fluid sample cell. The body-mountable device may indicate the current measurements wirelessly using an antenna.

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

Abstract: A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component.

Abstract: Apparatus for allowing measurements to be made of a blood sample comprises a shaft and at least first and second blood collection members. The blood collection members are independently rotatable about the shaft. Each blood collection member includes: a blood analysis part for receiving a blood sample, plural conductive contacts, and plural conductors extending between the blood analysis part and respective ones of the conductive contacts. The apparatus also includes plural terminals configured to provide an electrical connection with the plural conductive contacts on a first member when the apparatus is in a first configuration and to provide an electrical connection with the plural conductive contacts on a second member when the apparatus is in a second configuration, thereby allowing successive measurements of at least one parameter of blood samples provided on the blood analysis parts of the first and second members.

Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed.

Abstract: Devices, systems, kits and methods for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip, (iii) a feedback control mechanism, (iv) two or more electrodes, and (v) an electrical motor. The feedback control mechanism may be an internal feedback control mechanism or an external feedback control. The kit contains the controlled abrasion-device, one or more abrasive tips, optionally with a wetting fluid. The method for increasing the skin's permeability requires applying the controlled abrasion device to a portion of the skin's surface for a short period of time, until the desired level of permeability is reached. Then the abrasion device is removed, and a drug delivery composition or device or an analyte sensor is applied to the treated site.

Abstract: A system including a monitoring device dimensioned for placement on a human. The monitoring device including a plurality of sensors for monitoring a sleep position, a temperature, a carbon dioxide level and a respiration of the human. The system further including a processing unit coupled to the monitoring device, the processing unit capable of processing information from the plurality of sensors and performing an algorithm to determine the presence of a sudden infant death syndrome (SIDS) risk factor based on the information. A method may include monitoring two or more of a sleep position, a respiration, a temperature and a carbon dioxide level of a subject. An algorithm may be automatically performed based on the monitoring, to determine the presence of a SIDS risk factor. The results of the algorithm may be displayed and an alert can be sent to, for example, a mobile device based on the risk level.

Abstract: Surgical devices and methods for utilizing optical coherence tomography (OCT) to monitor and control tissue sealing are disclosed. The surgical device includes an end effector assembly that includes first and second jaw members that are movable between a first, spaced-apart position and a second proximate position. An OCT system, at least a portion of which is incorporated into the end effector assembly, is configured to sense properties of the tissue, e.g., the structural density of the tissue, disposed between the first and second jaw members. A tissue-sealing energy source may be disposed within at least one of the jaw members and may provide tissue-sealing energy to tissue disposed between the jaw members. A controller, which is coupled to the OCT system and the tissue-sealing energy source, controls the tissue-sealing energy generated by the tissue-sealing energy source based on the properties of the tissue sensed by the OCT system.

Abstract: Various portable systems, devices and methods for imaging or visualizing blood vessels or other body tissue to facilitate accurate placement of a needle or other elongate instrument in blood vessels or other body tissue are described herein. In certain variations an imaging system for aiding needle insertion in a patient may include a mountable unit having an illumination source, an image sensor, and a display for displaying an image based on image information from the image sensor. The mountable unit may be configured for attachment to a hand of a user such that the user's hand on which the unit is mounted remains free to hold an object. The display may be positioned next to a needle insertion site during needle insertion by the user such that the needle insertion site and an image of the blood vessel and/or needle are simultaneously within the user's field of view.

Abstract: Provided is an object information acquiring apparatus having: a light source; a probe that converts an acoustic wave generated from an object, onto which light is irradiated from the light source, into a detection signal; and a signal processor that obtains characteristic information inside the object based on the detection signal, wherein the signal processor obtains the characteristic information using information regarding a characteristic structure of a measurement target inside the object.

Abstract: A hermetically sealed electronic closure device, or button, includes a self-renewing power source, a sensor for measuring a metric, a memory storing information, a data processing circuit for controlling operations of the device, and a transceiver for sending and receiving information. The device is a standard part of a clothing item that is inconspicuous to a wearer of the clothing item.

Abstract: Biometric monitoring devices, including various technologies that may be implemented in such devices, are discussed herein. Additionally, techniques, systems, and apparatuses are discussed herein for providing power-conserving techniques and systems for efficiently utilizing a GPS receiver are described. The positional fix frequency of the GPS receiver may, according to some implementations, be modified or adjusted between various levels according to data from one or more non-GPS sensors. Such non-GPS sensors may include, for example, ambient light intensity or spectrum sensors, accelerometers, gyroscopes, magnetometers, heart rate sensors, galvanic skin response sensors, infrared sensors, etc.

Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided.

Abstract: A method, including acquiring a body cavity image and receiving first and second sets of mapping points from a probe inserted into the cavity. A first registration, having a first cumulative error value, is performed between the first set's mapping points and the image, each of the first set's mapping points having a respective first point error value, and a 3D anatomical map is generated including the first set's mapping points whose respective first point error values are less than a specified threshold. A second registration is performed between the received mapping points and the image, each of the received mapping points having a respective second point error value, the second registration having a second cumulative error value lower than the first cumulative error value, and an updated 3D anatomical map is generated including the received mapping points whose respective second point error values are less than the specified threshold.

Abstract: A medical apparatus and system for determining contact assessment includes a catheter having an elongate body having a proximal end, a distal end opposite the proximal end, and defining an injection lumen and an exhaust lumen, an expandable membrane defining a cooling chamber disposed at a point along the elongate body, the cooling chamber in fluid communication with the injection lumen and the exhaust lumen, and a contact assessment element which may be a temperature sensor located proximate the coolant return lumen for measuring an internal temperature of the chamber. The system may include the catheter, a console having a fluid supply, an exhaust path and at least one control mechanism operationally coupled to the temperature sensor for processing a temperature signal received from the temperature sensor. The apparatus and system can also have multiple electrodes to measure and process various impedances to determine contact assessment.

Abstract: A support apparatus in which a distribution of a load for a user can be designated. The load occurs at body parts of the user by a stand-up motion. A processor calculates a projection position of a center of gravity of the user onto a floor, calculates a region of the floor where the projection position is to be included at the stand-up motion, calculates a target position in the region based on the distribution, and calculates a direction from the projection position to the target position. The target position is nearer to one body part of the user to which a larger load distribution is designated than on other body parts to which a smaller load distribution is designated. A designation direction for the user to bend the body in advance of the stand-up motion is output based on the direction.

Abstract: A method of prioritizing arrhythmia alarms based on one patient's perfusion level includes receiving arterial blood pressure, electrocardiogram heart rate, and arterial pulse rate values of the one patient during a same time window. Analyzing the set of blood pressure values to determine if an arrhythmia event is indicated, where if an arrhythmia event is indicated, the method includes calculating a systolic blood pressure (SBP) ratio, comparing the SBP ratio to a first predetermined threshold, and if the SBP ratio is less than or equal to the first predetermined threshold, then activating a non-perfusion alarm. If the SBP ratio is greater than the first predetermined threshold, then calculating a standard deviation of a rate differential between the heart rate and the pulse rate values, and if the standard deviation is greater than a second predetermined threshold, then activating the non-perfusion alarm. A system and non-transitory computer media is also presented.

Abstract: The present invention relates to a device and a method for determining the position of an instrument with respect to medical images of a body. The device comprises (1) a calibration support comprising a set of fiducial markers visible on medical images and fixed to the skin of a body, (2) at least one micro-camera providing video images and mounted on the calibration support in a known position, and (3) a processing unit connected to the micro-cameras and configured to process the video images from said micro-cameras to determine the position of the instrument with respect to medical images.