Abstract: Casting jigs, methods, and kits that may be used in manufacture of anatomical healing caps. A casting jig may include a body having one or more wells within the body, each well being open at a proximal end thereof and having a negative shape corresponding to an anatomical healing cuff body of a given tooth position. Each respective anatomical healing cuff body negative shape includes an asymmetrical cross-section and an irregular surface so that an anatomical healing cuff body having said shape is configured to provide substantially custom filling of at least an emergence portion of a void where a natural tooth once emerged or should have emerged from the void (e.g., in the case of a congenitally missing tooth). The casting jig may further include a socket at a distal end of each well that is configured to receive therein a dental implant or dental implant analog.

Abstract: An oral care device suitable for use in providing a beneficial effect to an oral cavity of a mammal, which device includes means for providing reciprocation of a liquid effective for providing the beneficial effect of the oral cavity when the liquid is contacted with a plurality of surfaces thereof under conditions effective to provide the beneficial effect.

Abstract: The transmission according to the invention for an electric toothbrush serves for the transmission and reforming of a rotational movement provided by an electric motor into a particularly careful and effective cleaning movement of a cleaning element. The ratio of the distance between the longitudinal mid-axis of an output shaft and the longitudinal mid-axis of a drive shaft of the transmission and of the distance between the longitudinal mid-axis of a shaft driving a cam of the transmission and the longitudinal mid-axis of the cam amounts to at least 10:1.

Abstract: An instrument for curing light-curable compounds curable in the mouth of a patient, including a housing including a handle portion and a barrel portion removably secured with respect to the handle portion. A plurality of solid state, light-emitting semiconductor junction elements form an array on a substrate, and collectively emit light having wavelengths within a narrow band of wavelengths suitable for curing a compound. The array of light-emitting elements are positioned proximate to the distal end of the barrel portion, and an elongated heat-conducting element extends from the distal end of the barrel portion toward the proximal end for conducting heat away from the array. A generally clear layer extends on the substrate and over the plurality of light-emitting semiconductor junction elements, and a non-imaging optical focusing device is positioned at the distal end of the barrel portion to collimate the emitted light.

Abstract: The present invention relates apparatus for holding material to be dispensed in a surgical setting, and in particular that: (a) allows for small portions of material to be dispensed efficiently, (b) resists evaporation of volatile agents in the material being dispensed, (c) reduces exposure of the material to light and actinic radiation during intermittent use, and (d) supports autoclaving in order to fulfill sterilization standards in surgical setting.

Abstract: A closed system mouthpiece uses light and heat generation to activate a gel formulation to increase its volume. The gel formulation is coated into the mouthpiece, which is inserted into the user's mouth. Application of heat above a threshold temperature causes the gel to transform into foam and expand out of the mouthpiece and into the oral cavity. The mouthpiece creates a hermetic seal such that the foam expands out throughout the oral cavity into nooks and crannies that are normally difficult to access. Activation of a light source embedded within the mouthpiece enhances the bacteria killing properties of the foam material. The pH balance of the mouth is restored by the inventive method and apparatus to a neutral level in the range of 6.75 to 7.25.

Abstract: An apparatus for removably retaining a single use cartridge and dispensing at least one compound from the single use cartridge. The apparatus includes a dispensing pen having a housing which includes a source of electricity, an electric motor, a gear assembly and a moving shaft with a multiplicity of teeth to cause an advancing shaft to move forwardly toward the front of the pen and interact with a piston to push a plunger at the rear of the cartridge so that it will dispense compounds from the cartridge. The cartridge can be a single chamber cartridge or a dual chamber cartridge or a dual chamber cartridge separated by a dividing wall. There can be any numerous compounds including teeth whitening compounds, nail polish, cosmetics, etc.

Abstract: A system and method for monitoring the health of an animal using multiple sensors is described. The wearable device may include one or more sensors whose resultant signal levels may be analyzed in the wearable device or uploaded to a data management server for additional analysis. In one example, paired thermometers are used to estimate a core temperature of the animal, with one of the thermometers facing inward toward the animal and the other thermometer facing away from the animal.

Abstract: Various embodiments of a mesh or implant systems are provided. The implants can include one or more anchors, arms and the like. The anchors can include hingeable or patterned finger extension to facilitate tissue penetration and retention. Various tensioning and adjustment mechanisms, devices and methods are further provided for the implant systems.

Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect is provided. The implantable prosthesis includes a first biocompatible structure having a tether attached thereto for maintaining stable deployment of the implantable prosthesis through an abdominal wall; a rigid reinforcement member positioned adjacent a bottom side of the first biocompatible structure, the rigid reinforcement member including an inner circumferential ring, a plurality of spoke elements, a plurality of openings, and a plurality of guide members molded thereon; a mesh structure positioned adjacent a bottom surface of the rigid reinforcement member, the mesh structure overlapping the inner circumferential ring of the rigid reinforcement member; a second biocompatible structure and an anti-adhesion barrier having a collagen coating positioned on a bottom surface of the second biocompatible structure.

Abstract: The invention provides an embolic protection device for removing emboli from a blood vessel in a patient's body. The device comprises an elongate host element, an embolic protection element having a collapsed configuration and an expanded configuration, and a flexible tether connected to a distal end of the host element and to a proximal portion of the embolic protection element. The tether allows the host element to move axially and laterally relative to the embolic protection element over a limited range of motion when the embolic protection element is in an expanded configuration. The embolic protection device has a landing zone of 4 cm or less.

Abstract: An implantable digestive organ is provided for the transport of materials through the digestive tract and in one particular application to an artificial large bowel for replacing all or part of a colon. The prosthetic organ of one embodiment includes an outer support structure, an expandable member or members located within the support structure, and a flexible inner member forming a conduit for passage of material. The inner member is located within the outer member and the expandable member(s) is located between the inner member and the support structure. The expandable members are expanded and contracted, or inflated and deflated to provide pumping action that pumps material through the organ. The prosthesis may also include valves or sphincters at its entrance and/or exit points where material moves into and out of the prosthesis. An implantable pump may be included for inflating and deflating the expandable members in a desired sequence.

Abstract: Modular endograft devices and associated systems and methods are disclosed herein. In several embodiments, an endograft system can include a first endograft device and a second endograft device that each include an integrated frame, a cover and a lumen within the cover. Each endograft device further includes a superior portion and an inferior portion. The superior portion can have a convexly curved outer wall and a septal wall. The first and second endograft devices can be configured to extend into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand into an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension and a second length less than the first length. In the expanded configuration, the septal walls can press against each other and form a septum between the lumens of the first and second endograft devices.

Abstract: Hydrogel jacketed stents provide the ability to fill in the stent frame in vivo to at least partially cover the interior of the surface of the stent following deployment while having the convenience of attaching the jacket to the exterior of the stent. The hydrogel can be pleated and/or folder over the exterior of the stent to provide for extension of the stent without damaging the hydrogel. The hydrogel sheet can be secured at one or more points along the circumference to associate the sheet of hydrogel with the exterior surface of the stent frame. The stent can be conveniently delivered using similar technology as conventional stents if desired. The hydrogel can provide for drug delivery if desired.

Abstract: A self-sealing vascular graft, including a substrate with a sealant layer and several optional additional layers, is described. The substrate can be ePTFE and the material used for the sealant and additional layers can be polyurethane. The sealant layer and additional layers may include one or more base layers, one or more foam layers, beading of different sizes and shapes, and ePTFE tape. A flared cuff may be integral to one or both ends of the substrate or may be attached to one or both ends. Various methods of making a self-sealing vascular graft are also described, including methods of disposition, methods of forming, methods of bonding and methods of attaching.

Abstract: A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. A collapsible tube is positioned about the suture. Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel and the collapse of the tube to form an anchor.

Abstract: A skin weft with artificial hair attached thereto to provide various styling options or ample volumetric feeling. The skin weft comprises a stitched portion formed by stitching on a side edge of artificial hair composed of human hair or resin hair, a resin tape welded to a surface of the stitched portion, and a bonding component attached to a surface of the resin tape. The method for manufacturing the skin weft comprises the steps of forming a stitched portion by stitching one side edge of human hair or resin hair arranged and conveyed in the form of a sheet, and supplying a resin tape onto a surface of the stitched portion to form a bonding portion. Automatic mass production is achieved, thereby improving productivity and significantly reducing manufacturing costs. Additional means are unnecessary in the manufacturing process, thereby enabling an unskilled person to perform the task.

Abstract: An intraocular lens that is capable of being inserted through a micro-incision includes an optic having an anterior and a posterior surface and a plurality of projections extending from the anterior and posterior surfaces. The anterior and posterior surfaces include a recess. The optic is implanted such that a rim of the capsulorhexis is disposed in the recess such that the plurality of projections grip the capsular bag.

Abstract: A cartridge for storing and implanting an intraocular lens has a first part and a second part that are movable relative to one another from a storage configuration, in which interior surfaces of the first and second portions define a storage chamber for storing the IOL in an unfolded state, to an implanting configuration, in which the interior surfaces of the first and second portions together define a smooth-bored implanting chamber for retaining the IOL in a folded state. According to a first aspect, the first and second portions are hinged together, whereas according to a second aspect, the first and second portions are slidably interconnected.

Abstract: A prosthetic heart valve (10) (e.g., a prosthetic aortic valve) is designed to be somewhat circumferentially collapsible and then re-expandable. The collapsed condition may be used for less invasive delivery of the valve into a patient. When the valve reaches the implant site in the patient, it re-expands to normal operating size, and also to engage surrounding tissue of the patient. The valve includes a stent portion (200) and a ring portion (100) that is substantially concentric with the stent portion but downstream from the stent portion in the direction of blood flow through the implanted valve. When the valve is implanted, the stent portion engages the patient's tissue at or near the native valve annulus, while the ring portion engages tissue downstream from the native valve site (e.g., the aorta).

Abstract: A method for reducing an axial profile of a valve implant includes providing a valve implant having a longitudinal axis and a delivery catheter having a central axis and a distal receiving section. The method further includes helically rolling the valve implant around a rolling axis that is offset at an angle of about 15 degrees to about 60 degrees with respect to the longitudinal axis to form a rolled valve implant having a rolled axis, where the rolled axis is the same as the rolling axis. The method further includes aligning the rolled axis of the rolled valve implant with the central axis of the delivery catheter. The method further includes inserting the rolled valve implant into the distal receiving section of the delivery catheter.

Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.

Abstract: Methods and systems for delivering and deploying a prosthetic heart valve include a deployment mechanism coupled to the prosthetic heart valve, the deployment mechanism having a longitudinal shaft that when rotated in a first direction, expands the prosthetic heart valve from a contracted state to an expanded state, and optionally, when rotated in a second direction opposite the first direction, re-contracts the prosthetic valve from the expanded state. Embodiments of the deployment mechanism include a pinion gear that engages a gear track on the prosthetic heart valve.

Abstract: A medical assembly for replacing a native heart valve of a patient. The medical assembly includes a radially expandable and collapsible prosthetic heart valve having a self-expandable stent body and a plurality of leaflet-forming membranes. The medical assembly also includes a deployment mechanism configured to deploy the prosthetic heart valve within the native heart valve of the patient. The deployment mechanism preferably includes a plurality of proximal deployment members coupled to a proximal end of the stent body. The deployment mechanism may also include a plurality of distal deployment members coupled to a distal end of the stent body. The prosthetic heart valve desirably includes a mechanical locking device configured to lock the prosthetic heart valve in a radially expanded configuration.

Abstract: A method for delivering a prosthetic valve to a patient's heart having a native valve with a plurality of valve leaflets includes providing a delivery device with a prosthetic valve, advancing the delivery device toward the native valve, and expanding a portion of the prosthetic valve to form a flanged region that is upstream of the valve leaflets. One or more tabs on the prosthetic valve are released so that they expand outward to a position that is transverse to the longitudinal axis of the prosthetic valve. The position of the prosthetic valve is adjusted relative to the valve leaflets and rapid pacing is applied to the patient's heart so that the valve leaflets move inward toward the prosthetic valve or the delivery device. The tabs are further released to allow the tabs to move into their final positions.

Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.

Abstract: Devices and methods for treating or repairing a heart are disclosed. The device includes at least one radially expandable tissue-engaging element, an elongate member (e.g., suture) coupled to the expandable element, and a locking mechanism (e.g., locking clip, suture knot). The expandable element may be anchored to heart tissue within the heart, such as in the left ventricle, with the elongate member extending from the expandable element and across a heart chamber to a second location such as the heart apex where the elongate member is held by the locking mechanism.

Abstract: The invention relates to an implant and a set for producing an implant and their uses. Furthermore, the invention describes a method of making an implant as per the invention. An implant for producing bone implants with improved mechanical characteristics, especially with adjustable mechanical characteristics, is provided via the invention. The implant as per the invention made up of a fiber composite material contains resorbable mineral bone cement as the matrix material, to which reinforcing, long metal fibers and/or endless metallic fibers with an aspect ratio of at least 100:1 are added in the form of at least one fiber structure that provides a framework and that preforms the contour of the implant.

Abstract: Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are optimized for the expected stress applied at the bone structure site.

Abstract: An apparatus for facilitating the mounting of a prosthetic articulation surface to a patient tissue includes an anchoring base including a central fastener aperture extending longitudinally therethrough. A first base end is laterally spaced from the central fastener aperture. A second base end is laterally spaced from the first base end with the central fastener aperture laterally interposed therebetween. Both of the first and second base ends include a plate engagement feature. An anchor plate includes a central coupler aperture extending longitudinally therethrough. An outer perimeter is spaced laterally apart from the central coupler aperture. A plate rim extends laterally inward from the outer perimeter to substantially laterally surround the central coupler aperture. At least one plate fastener aperture extends longitudinally through the plate rim. At least one base engagement feature is located on the plate rim and is selectively engageable with the plate engagement feature of the anchoring base.

Abstract: The elbow prosthesis includes an ulnar component that has a bearing end and a stem. The stem is attached to the bearing end and extends in a distal direction from it. The elbow prosthesis also has a humeral component that includes a holder end and a stem with the stem extending in a proximal direction from the holder end. The prosthesis further includes at least one bearing member that is connected to the holder end with the bearing end being attached within the holder end to allow for rotation and articulation against the at least one bearing member. The bearing end and holder end are attached to each other by a coupling mechanism that includes an opening positioned on the posterior aspect of the holder end and a mating surface on the bearing body. A method of using the elbow prosthesis and a total elbow prosthesis kit are also disclosed.

Abstract: Certain disclosed examples provide methods for strengthening, reinforcing, and/or stimulating repair of residual patella bone to be resurfaced. Also provided in some examples are devices associated with the methods. These methods and devices may be utilized during or following total knee replacement (TKR) or total knee arthroscopy (TKA).

Abstract: An implant couples a first bone of a hand to a second bone of the hand. The implant includes a body that defines a median plane. The body also defines a first joint surface having a first central region that articulates with the first bone. The body further defines a second joint surface having a second central region that articulates with the second bone, and the second central region is disposed on an opposite side of the median plane of the body relative to the first central region. The first and second central regions correspond to profiles of first and second axial segments, respectively, the first and second axial segments are each one of a cylinder, a cone and a torus and are centered on first and second axes, respectively, and the first and second axes, as projected on the median plane, are substantially perpendicular to each other.

Abstract: A prosthesis for implantation in an animal or human subject, said prosthesis comprising a first component for attaching to a radius bone in use and a s second component for attaching to an ulna bone in use, the prosthesis further comprising a linkage for linking the first and second components substantially rigidly with respect to one another in use. Preferably the prosthesis is configured to allow the linkage to move relative to the first and/or second components and be retained substantially rigidly at a selected position in normal use, such that the first and second components can be retained substantially rigidly relative to one another in normal use.

Abstract: Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

Abstract: An inflatable balloon for diagnostics and treatment of diseased discs or fractured bones. The balloon is a multi-volume balloon comprised of a plurality of adjustable and expandable single volumes. Further disclosed are methods of forming, expanding, and implanting the multi-volume balloon for proper placement and stabilization of the diseased discs or fractured bones. Still further disclosed are kits for aligning and stabilizing a bone, disc, or spinal motion segment.

Abstract: An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.

Abstract: Tissue spacer implants and surgical methods for inserting the implants are disclosed. The implants may include a first cylindrical body with an outer surface, an axially extending hole, and a first end, a second cylindrical body with an outer surface and an axially extending hole, and an adjustment member with an outer surface, an axial hole, and at least one helical slot. The adjustment member axial hole may be adapted to receive the first cylindrical body and the adjustment member may be configured to be inserted into the axially extending hole of second cylindrical body. The implants may also include a travel mechanism for engaging the first cylindrical body, adjustment member, and second cylindrical body along the at least one helical slot to maintain a space between two bodies of tissue.

Abstract: This invention improves upon prior art total disc replacements (TDRs) by more closely replicating the kinematics of a natural disc. The preferred embodiments feature two or more fixed centers of rotation (CORs) and an optional variable COR (VCOR) as the artificial disk replacement (ADR) translates from a fixed posterior COR that lies posterior to the COR of the TDR to facilitate normal disc motion. The use of two or more CORs allows more flexion and more extension than permitted by the facet joints and the artificial facet (AF). AF joint-like components may also be incorporated into the design to restrict excessive translation, rotation, and/or lateral bending.

Abstract: A spinal implant includes a body, plate, and bone screws. The body includes a first wall having second and third walls joined thereto to define legs. In an embodiment, the body and plate are of unitary construction. In alternative embodiments, the body is formed from a first material and is configured for positioning between vertebral bodies. In other embodiments, the body is separate from the plate. The plate has a main portion and a flange. The main portion has a first screw hole oriented towards the first vertebral body at an oblique angle relative to the horizontal axis of the body. The flange has a second screw hole oriented towards the second vertebral body and substantially parallel to the horizontal axis. The flange is coupled to the main portion and extends past the main portion. Each bone screw is insertable through a screw hole of the plate for attachment to bone. A kit including a body, bone screws, and a plurality of different plates is also provided.

Abstract: The intervertebral three-dimensional structure comprises a top side, an underside, a front face, a rear face, and a plurality of boreholes designed to receive affixation elements.

Abstract: Provided are systems and methods for precise intra-operative placement and positioning of components of hip prostheses, particularly with respect to avoiding acetabular prosthetic implant malpositioning in the human hip. In one embodiment the system includes at least a pair of electronic sensors as tilt and direction sensors, which are positioned on the patient's native bone structure and the prosthesis, plus at least one of an electronic angle sensor and an electronic leg length measurement unit, plus a computer processor running application software that is capable of receiving and using information from the various electronic sensors to calculate relevant angular relationships and, optionally, distance relationships. The system electronically measures a living subject's pelvic tilt and position while lying in the lateral decubitus position during the surgery.

Abstract: A method of reproducing a central axis of a femoral neck prior to resection during an implantation process includes the step of attaching a frame to the acetabulum of a patient, wherein the frame includes first and second movable arms and a lockable swivel bearing. The method further includes the steps of orienting and locking the swivel bearing in position and utilizing the position of the swivel bearing to position acetabular instrumentation to match a planned acetabular implant orientation.

Abstract: An interbody insertion tool and cage for use during an interbody spinal fusion procedure is disclosed. In one aspect, the tool comprises a rod centrally located within the tool that has the ability to remain attached to the cage to aid in: coupling the tool to the cage, release of the tool from the cage, alignment of additional hardware, and insertion of materials within the hollow of the cage.

Abstract: An instrument for attachment to and insertion of an implant device is provided. The instrument has a handle and a pair of retaining posts extending longitudinally from a distal end of the handle. Each of the pair of retaining posts have an end dimensioned to engaged a respective threaded bore of the implant device. Also, a post drive mounted to the handle and mechanically connected to each of the retaining posts so as to engage the retaining posts simultaneously is provided.

Abstract: A system for repairing cartilage includes a trephine having a passage extending along a longitudinal axis of the trephine. The trephine has a distal end and a proximal end. The distal end includes a cutting member operable to cut a cartilage plug from a donor site. The passage is operable to receive the cartilage plug. Also, the trephine is flexible to selectively move between a first position in which the longitudinal axis is substantially linear and a second position in which the longitudinal axis is nonlinear. Moreover, the system includes a guide tool that is removably coupled to the trephine. The guide tool is operable to selectively move the trephine between the first and second positions. In addition, the system includes an ejector tool that ejects the cartilage plug from the passage toward a defect site.

Abstract: Devices and methods for aiding practitioners in the implementation of arthroplasty prosthetics. Example devices may include a base and an alignment arm, and may be used for finding and recording the native alignment of a bone head, such as the femoral or humeral head. The base may be attached to the bone and the alignment arm may be adjusted to reflect the native alignment of the bone. Once the alignment is recorded, the native bone head may be removed and the prosthetic bone head may be attached to the bone, and properly oriented using the alignment arm of the device.

Abstract: The invention relates to a finger prosthesis comprising a base element, which is formed to receive forces and torques and can be provided with an elastic covering to achieve a natural appearance. Furthermore, the invention relates to a hand prosthesis comprising a chassis and a finger prosthesis arranged on it.

Abstract: A prosthetic adapter including a lower connector, an upper connector rotatably coupled to the lower connector, and a locking mechanism for preventing the upper connector from rotating relative to the lower connector. The locking mechanism is arranged to generally automatically retain a locked position when the lower connector is rotated to an original, predetermined alignment. An activation member is connected to and arranged for operating the locking mechanism.

Abstract: The invention relates to a device and method for controlling an artificial orthotic or prosthetic joint of a lower extremity, comprising a resistance unit with which at least one actuator is associated, via which the bending and/or stretching resistance is varied depending on sensor data. During the use of the joint, status information is provided via sensors. According to the invention, the resistance is increased in the standing phase or while standing from a starting value depending on the ground reaction force up to a locking point of the joint.