Abstract: The invention comprises an apparatus for determining the contextual or physiological status of the individual wearing the apparatus. The apparatus is designed to be consumable or disposable. In most embodiments the invention comprises an adhesive housing. In some embodiments, two different sensors are secured to the housing. The apparatus is in electronic communication with a processing unit that can derive analytical status data by using the data received from the two sensors. In some embodiments, the processing unit is programmed to control other devices, or is programmed to trigger an event. In still other embodiments, the apparatus is in electronic communication with a separate computing device, which may contain the processing unit.

Abstract: A life maintenance mode named as the third type of life maintenance mode, includes decomposing inspection items of clinical diagnosis into a series of individual automatically measured and computed indicators of life condition data, popularized into people's daily life and work to be practiced continuously producing continuous diagnosis and inspection analysis report and trend; performing active control of the change of the life condition data by senior independent consciousness of cerebral cortex with the automatically measured and computed life condition data to serve as a quantitative traction device for treatment, rehabilitation, and health and longevity; predict and prevent the occurrence and development of diseases on the basis of the produced inspection analysis report and trend; automatically sending messages to remind a patient to check the treatment behaviors on the basis of doctor's advices and prescriptions in the track record of medical treatment, and providing an automatic no-response alarming s

Abstract: A measurement apparatus includes contact interfaces disposed in a housing so as to allow contact with test sites of a subject; biological sensors configured to acquire respective biological measurement outputs of the test sites contacting the contact interfaces; temperature detectors configured to detect respective temperatures of the contact interfaces; and a controller configured to measure biological information based on the temperatures obtained from the temperature detectors, and the biological measurement outputs obtained from the biological sensors.

Abstract: A measurement apparatus for measuring biological information by contacting a test site to a contact interface includes a contact state detector that detects a contact state of the test site on the contact interface, a biological sensor that acquires biological information from the test site, a notification interface, and a controller that measures the biological information based on output from the biological sensor. The controller judges the contact state of the test site on the contact interface based on output from the contact state detector and provides notification, via a notification interface, of information related to the contact state.

Abstract: A method of estimating a blood pressure is provided. The method of estimating blood pressure includes inputting physical characteristic information and blood pressure information of a subject, determining, among a plurality of groups classified according to hemodynamic characteristics, a group to which the subject belongs based on the physical characteristic information and the blood pressure information, detecting a bio-signal of the subject, extracting a plurality of features from the detected the bio-signal, and estimating a blood pressure corresponding to the extracted plurality of features and the determined group based on a learned blood pressure estimation algorithm.

Abstract: The invention relates to a method for determining blood pressure in a blood vessel, according to which a pulse wave propagation time is caluculated in a measuring operation by means of at least two sensors arranged at a defined distance from one another. The method is characterized in that the blood pressure is calculated using a calibration carried out by means of a compression pressure measurement.

Abstract: A system for measuring heart rate variability (HRV) comprising 3 sub-systems: a data collection sub-system, a data analysis sub-system, and an output sub-system. A patient is connected to a heart monitoring device such as an ECG and the data collection sub-system records the patients heart beats, and an ECG chart is produced from which the patient's HRV value is derived by the data analysis sub-system. The present invention obtains the HRV value through calculation of a new parameter called relative density (RD).

Abstract: A biological information detecting device includes: a first light receiving portion and a second light receiving portion which receive light from a subject; a processing portion; and at least one light emitting portion (light emitting portion or the like) which emits light to the subject. When a distance between the light emitting portion and the first light receiving portion is set to L1 and a distance between the light emitting portion and the second light receiving portion is set to L2, L1<L2 is satisfied. The processing portion performs body motion noise reduction processing that reduces a body motion noise of a first detection signal which is detected by the first light receiving portion based on a second detection signal which is detected by the second light receiving portion, and calculates biological information based on the first detection signal after the body motion noise reduction processing.

Abstract: Methods and devices for combining multiple signals from multiple sensing vectors for use in wearable or implantable cardiac devices. A preferred sensing configuration may be selected at a given point in time, for example under clinical conditions. Signal quality for the preferred sensing configuration is then monitored, and if the signal quality degrades under selected conditions, re-analysis may be performed to select a different sensing vector configuration for at least temporary use. If signal quality increases for the preferred sensing configuration, temporary use of the different sensing vector configuration may cease and reversion to the preferred sensing configuration takes place if certain conditions are met. The conditions for reversion may depend in part of a history of sensing signal quality for the preferred sensing configuration.

Abstract: A system for determining T wave bifurcation that includes three or more ECG leads configured to receive an ECG signal and a first computing device including a processor coupled to a memory, the processor and the memory configured to perform operations including: generating at least two orthogonal ECG vectors based on the ECG signal of a patient, processing the at least two orthogonal ECG vectors to determine a loop trajectory of at least a portion of the ECG signal, identifying a trajectory bifurcation by comparing the loop trajectory to a control loop trajectory for a plurality of cardiac cycles, and determining an indicator of a cardiac event based on the trajectory bifurcation.

Abstract: A method for computerizing delineation and/or multi-label classification of an ECG signal, includes: applying a neural network to the ECG whereby labelling the ECG, and optionally displaying the labels according to time, optionally with the ECG signal.

Abstract: A method for assessing the electrical function of a heart, a method for determining a subject's need for the implantation of an implantable cardioverter defibrillator or the need for administration of an anti-arrhythmic agent, and apparatus for assessing the function of the heart and a computer program product. The methods and products involve analysis of ECG.

Abstract: Systems and methods are provided for measuring electrical activity within a brain of a patient. An electrode array is configured to take measurements of electrical potential as raw electroencephalographic (EEG) data. A data processing component includes a spectral decomposition component configured to divide the raw EEG data into a plurality of frequency intervals, within a total range of frequencies and an inverse solution component configured to transform the raw EEG data associated with each frequency interval into a spatial mapping of electrical activity as to provide a set of parameters, with each parameter representing an average electrical activity at an associated location within the brain over an epoch of interest.

Abstract: Various embodiments of the present disclosure can include a flexible catheter tip. The flexible catheter tip can comprise an inboard understructure that defines a tip longitudinal axis, wherein the inboard understructure is formed from a first continuous element that includes a first rectangular cross-section. In some embodiments, an outboard understructure can extend along the tip longitudinal axis, wherein the outboard understructure is formed from a second continuous element that includes a second rectangular cross-section.

Abstract: An integrated electrode structure can comprise a catheter shaft comprising a proximal end and a distal end, the catheter shaft defining a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft, the flexible tip portion comprising a flexible framework. A plurality of microelectrodes can be disposed on the flexible framework and can form a flexible array of microelectrodes adapted to conform to tissue. A plurality of conductive traces can be disposed on the flexible framework, each of the plurality of conductive traces can be electrically coupled with a respective one of the plurality of microelectrodes.

Abstract: An apparatus for determining whether the brain is fatigued may include: an electroencephalogram signal collection module for collecting electroencephalogram signals of a testee; a quantization processing module for quantifying the electroencephalogram signals utilizing a sample entropy algorithm to obtain a final sample entropy value of the electroencephalogram signals; and a fatigue state determination module for determining whether the brain of the testee is fatigued according to the final sample entropy value, wherein it is determined that the brain of the testee is in a fatigue state when the final sample entropy value is within a predetermined range.

Abstract: A life maintenance mode named as the third type of life maintenance mode, includes decomposing inspection items of clinical diagnosis into a series of individual automatically measured and computed indicators of life condition data, popularized into people's daily life and work to be practiced continuously producing continuous diagnosis and inspection analysis report and trend; performing active control of the change of the life condition data by senior independent consciousness of cerebral cortex with the automatically measured and computed life condition data to serve as a quantitative traction device for treatment, rehabilitation, and health and longevity; predict and prevent the occurrence and development of diseases on the basis of the produced inspection analysis report and trend; automatically sending messages to remind a patient to check the treatment behaviors on the basis of doctor's advices and prescriptions in the track record of medical treatment, and providing an automatic no-response alarming s

Abstract: One aspect of the present disclosure relates to a system to facilitate at home neural monitoring. The system can include a wearable device and an external device. The wearable device can include an electrode configured to be placed behind a patient's ear to record an electroencephalogram (EEG) signal; an amplifier to amplify the EEG signal; a battery; and a wireless transmission system to transmit the amplified EEG signal. The external device can be configured to receive the amplified EEG signal and to perform analysis of the amplified EEG signal. In some instances, the external device can also provide neural stimulation (e.g., acoustic, visual, or electrical) to the wearable device in response to analysis of the amplified EEG signal.

Abstract: A wireless probe for electromyography to be used in dentistry, suitable for acquiring data even in the absence of a receiving unit, which is easily positionable onto and removable from the patient's face. The wireless probe preferably includes a first recording electrode and a first device provided with a second recording electrode.

Abstract: MR imaging and intervention functions are localized within a single device. At least one integrated coil device which has at least one RF coil, a housing which encases the RF coil and provides an anatomically conformal surface, and a plurality of apertures. The integrated coil device slides along a guide rail system to adjust the size of a patient anatomical imaging region. The apertures in the integrated coil device are available to secure tool holder grid plate inserts or other interventional device guides. The inserts assist in holding the soft tissue for diagnostic imaging and provide support for biopsy/interventional instrument guides. The integrated MR imaging and interventional coil device works in combination with a prone patient support structure, an adaptive torso sling, and also features an open architecture design for improved patient access. The device also works for supine or side imaging procedures.

Abstract: Disclosed are systems, devices, and methods for registering a luminal network to a 3D model of the luminal network. An example method comprises generating a 3D model of a luminal network, identifying a target within the 3D model, determining locations of a plurality of carinas in the luminal network proximate the target, displaying guidance for navigating a location sensor within the luminal network, tracking the location of the location sensor, comparing the tracked locations of the location sensor and the portions of the 3D model representative of open space, displaying guidance for navigating the location sensor a predetermined distance into each lumen originating at the plurality of carinas proximate the target, tracking the location of the location sensor while the location sensor is navigated into each lumen, and updating the registration of the 3D model with the luminal network based on the tracked locations of the location sensor.

Abstract: Techniques for using the sensor subsystems built into typical smart devices such as a smartphone to detect, measure, collect and characterize air pressure waveforms and make recommendations. The approach is particularly adaptable to detecting respiratory conditions but may also be used in other applications.

Abstract: A device and a method for the analysis of the air exhaled by a subject in order to measure basal metabolism of the subject comprise a main line for a sampling flow of the air exhaled by a subject who breathes spontaneously or a subject undergoing assisted pulmonary ventilation. A mixing mini-chamber is provided for mixing a plurality of air sampling flows exhaled by the subject within a number of respiratory cycles. Sensors for sensing the oxygen concentration and the carbon dioxide concentration respectively measure the oxygen concentration and the carbon dioxide concentration within the air flow in the main line. The device further comprises an electronic control unit which processes signals from the sensors for obtaining a measurement of metabolism of the subject within a number of respiratory cycles.

Abstract: An airway adaptor includes: an airway case; and an expired gas guiding portion which is connected to the airway case to introduce a respiratory gas to the airway case. The airway case includes: a first respiratory gas flow path in which the respiratory gas flows in a first direction; and a second respiratory gas flow path in which the respiratory gas flows in a second direction opposite to the first direction.

Abstract: A signal processing method including receiving a signal, compressing the signal through a sampling of the signal, and generating transmission data of the signal by matching at least one feature indicating characteristics of the signal.

Abstract: The present disclosure relates to a positioning system suitable for use in an imaging system. The positioning system may include one or more cameras configured to capture images or videos of an imaging object and surrounding environment thereof for ROI targeting or patient position recognition. The positioning system may also include one or more position probes and sources configured to determine an instant location of an imaging object or an ROI thereof in a non-contact manner.

Abstract: A method for an assessment of a movement of a limb-related point in a predetermined 3D space effected by a user displacing the limb in the 3D space is provided. The method includes the steps of providing display surfaces in the 3D space around the user, providing a limb position point connected to a portion of the user's limb associated to the limb-related point, and providing sensors to detect the limb position point in the 3D space in relation to the joint. A computer program calculates a direction defined by a straight line between the joint and the limb-related point and provides a representation of the position of the limb-related point in the 3D space as a function of a distance between the joint and the limb-related point on one of the display surfaces on the line.

Abstract: Computer-implemented methods and systems for con-currently capturing video imagery with a 3D infrared camera, an audio commentary, and at least one set of physiological data during a mammalian subject's performance of one or more selected musculoskeletal movements for use in assessments of their range of motions.

Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane with low temperature sensitivity. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

Abstract: This invention discloses a bio-sensing apparatus and a sensing method thereof. The bio-sensing apparatus comprises at least one light sensor, reflection light module, transmission light module and control module, wherein the bio-sensing apparatus can provide two different lights from the up and down side of the finger, and calculate the blood glucose information by sensing the spectrum to provide the more precision measurement of the blood glucose concentration.

Abstract: Methods to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided. Systems to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided. Kits to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided.

Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ ‘just the right amount of oxygen,’ or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.

Abstract: A system and method for optimizing a stimulus, comprising a presentation device for presenting a stimulus to a subject, at least one biological sensor for measuring at least one biological parameter of a subject, and a computing device configured to determine a subject's emotional state in response to each stimulus, rank the stimuli in response to the subject's emotional state, use the higher-ranked stimuli to generate new stimuli, and present the new stimuli to the subject via the presentation device.

Abstract: A diagnosis supporting device includes a display, an imaging unit configured to capture a subject, an eye gaze detector configured to detect an eye gaze direction of the subject from a captured image captured by the imaging unit, a gaze point detector configured to detect a gaze point of the subject in a display region of the display, based on the eye gaze direction, an output controller configured to display, on the display, a diagnosis image that includes a person image and a geometric pattern image, and in which at least one of contrast, color density, and a degree of transmittance of the person image or the geometric pattern image is changed over time, and an evaluator configured to calculate an evaluation value of the subject, based on the gaze point detected by the gaze point detector when the diagnosis image is displayed.

Abstract: A sensor plaster (116) for the transcutaneous measurement of an organ function, more particularly of a kidney function, is proposed. The sensor plaster (116) comprises at least one flexible carrier element (134) having at least one adhesive surface (138) which can be stuck onto a body surface. Furthermore, the sensor plaster (116) comprises at least one radiation source, more particularly a light source (142), wherein the radiation source is designed to irradiate the body surface with at least one interrogation light (162). Furthermore, the sensor plaster (116) comprises at least one detector (146) designed to detect at least one response light (176) incident from the direction of the body surface.

Abstract: A brain disorder evaluation apparatus adjusts a prompt cycle of body movement tasks according to individual differences, and includes: a body movement prompt unit, which prompts body movement tasks to a subject; a body movement detection unit, which detects body movement data of a subject; an operation input unit, which receives the input information; an output unit; a storage unit; and a data processing unit which includes, a body movement task selection part, which selects the body movement tasks, a data obtainment part, an indicative data generation part, which generates an indication cycle by means of information input from the operation input unit and the body movement accuracy obtained by the calculations of a body movement accuracy computation part, and generates indication data according to the above-mentioned indication cycle, the body movement accuracy computation part, and a cognitive impairment degree evaluation part.

Abstract: A system and method for assessing brain health includes presenting a saccade test to a subject and capturing biological sensor data of the subject in response to the saccade test using a plurality of biological sensors. Saccade cards are employed to measure the brain health of a subject through collection of eye tracking data, for example. Saccade cards using a variety of design elements besides numbers are used for collection of the eye tracking data and other biological data. The captured biological data is used to create a multi-variate signature of the brain health condition of the subject.

Abstract: The invention provides a biosensor for at least partial insertion in a fetal scalp, for monitoring an analyte in the body of the fetus, wherein the biosensor comprises a needle and a microdialysis element for sampling the analyte. The invention also provides a sensing system comprising the biosensor, configured to flow a liquid through the microdialysis element. The invention can be used for e.g. lactate sensing as well as releasing a pharmaceutical. Hence, the biosensor and/or sensing system may also be used for delivery of a pharmaceutical or nutrient to a fetus.

Abstract: A level-of-health determining device includes: a characteristic quantity acceptor to which a characteristic quantity extracted from a taken image of an organ of an examinee to be used for level-of-health determination is input; and a determiner which compares the examinee's characteristic quantity input via the characteristic quantity acceptor with a distribution of a characteristic quantity of a population and which thereby determines a disparity of the examinee's physical constitution, which corresponds to an individual difference from other people, and a change of the examinee's physical condition. When determining the disparity of the examinee's physical constitution, the determiner uses, as the distribution of the population's characteristic quantity, a distribution of a characteristic quantity of the other people.

Abstract: An information processing system, computer readable storage medium, and methods for analyzing the airflow related health of a person. A method includes obtaining an audio sample of a person's verbal communication, obtaining geographic information of the person, querying a remote server based on the geographic information, and obtaining additional information from the remote server, the additional information being related to the geographic information, and extracting contours of amplitude change from the at least one audio sample over a period of time, the contours of amplitude change corresponding to changes in an airflow profile of the person. The method further includes correlating the contours of amplitude change with periodic episodes typical of airflow related health problems, and determining, based at least on the additional information, whether the contours of amplitude change result from at least one local environmental factor related to the geographic information.

Abstract: Systems and methods for measuring biologically and behaviorally based responses to social media, locations, or experiences and providing instant and continuous feedback in response thereto are disclosed. An example system includes a first sensor to determine an emotional response of a user exposed to a social media application, a second sensor to determine a current activity of the user, and a third sensor to determine an environment of the user. The example system also establishes a priority schedule based on the emotional response, the current activity, and the environment. The system also correlates, based on the priority schedule, an advertisement with at least one of the emotional response, activity, or the environment. In addition, the example system presents the advertisement based on the priority schedule and the correlation of the advertisement with the at least one of the activity, the environment, or the emotional response.

Abstract: A software and hardware system is described that enables effective lifestyle management by providing a dynamic assessment of a user's physical and behavioral metrics via a high feedback ratio interface.

Abstract: An eyelid position sensor system and/or an eye movement sensor system for an ophthalmic lens having an electronic system is described herein for recording data associated with sleep of the wearer. The eyelid position sensor system is part of an electronic system incorporated into the ophthalmic lens. The electronic system in at least one embodiment includes a system controller and a data manager. In at least one embodiment, the eyelid position sensor system is utilized to determine eyelid position and the eye movement sensor system is utilized to determine eye position for the system controller to determine if the wearer is awake, asleep, or in REM sleep.

Abstract: Aspects of the subject disclosure may include, for example, detecting, by a substance delivery system coupled to a body part of an individual, an input signal not associated with a biological measurement of the individual, determining from the input signal, by the substance delivery system, whether delivering a dosage of a substance stored in the substance delivery system is needed and conforms to a dosage policy, and responsive to determining from the input signal that delivery of the dosage of the substance is needed and conforms to the dosage policy, initiating, by the substance delivery system, delivery of the dosage of the substance to the body part of the individual. Other embodiments are disclosed.

Abstract: A physical therapy assembly includes a measuring device that may be manipulated thereby facilitating the measuring device to measure a plurality of range of motion tests. The measuring device comprises a plurality of rulers is movably coupled together. Thus, the measuring device may form at least one selected angle. A plurality of goniometers is provided. Each of the goniometers is rotatably coupled to the measuring device. Thus, each of the goniometers may measure the at least one selected angle.

Abstract: A sensing bone fixing element includes a fixing portion, a fastening portion, a capacitor structure, and a coil. The fastening portion is fixed to the fixing portion and suitable for being fastened to a bone. The fastening portion passes through the capacitor structure which has a capacitance value and includes a first conductive layer, a second conductive layer, and an elastic dielectric layer. The first conductive layer leans against the fixing portion, the second conductive layer leans against the bone, and the elastic dielectric layer is located between the first conductive layer and the second conductive layer. The coil has an inductance value, and two ends of the coil are respectively connected to the first conductive layer and the second conductive layer. The coil receives a detection radio frequency (RF) signal and generates a responding RF signal according to variations in the capacitance value and the inductance value.

Abstract: A method of determining a degree of hydration of a sample, by generating a radio frequency signal with a frequency of no less than about two megahertz. The radio frequency signal is directed into the sample with an antenna that does not contact the surface of the sample. A reflected radio frequency signal is received from the sample and compared to the reflected radio frequency signal. Differences between the directed radio frequency signal and the reflected radio frequency signal are correlated to a degree of hydration of the sample.

Abstract: Provided are a method of controlling a wearable device and a wearable device. The method of controlling the wearable device includes: determining whether a sensor provided in the wearable device is in an activated state; controlling an adherency controller for adjusting adherency between the sensor and a body of a user wearing the wearable device based on whether the sensor is in the activated state; and detecting a biosignal via the sensor.

Abstract: A system for measuring physiological parameters, including: a portable measurement system, operable to acquire physiological measurement from an examined body location; an external camera operable to capture visible light, oriented toward the examined body location; a synchronization module, operable to receive a triggering indication, and in response to the triggering indication to associate to the physiological measurement a positioning image captured by the camera, the positioning image including at least a part of the portable measurement system adjacent to the examined body location; and a communication module operable to obtain the physiological measurement and the positioning image, and to transmit to a remote system: a physiological measurement record based on the physiological measurement, an orientation image based on the positioning image, and including at least a part of the portable measurement system adjacent to the examined body location, and association data associating the orientation image a

Abstract: A calibration packaging apparatus for a physiological monitoring garment is disclosed. The apparatus comprises a chamber to hold a physiological monitoring garment with a plurality of position sensors, motion sensors, or position and motion sensors. The apparatus is configured to calibrate the plurality of position sensors, motion sensors, or position and motion sensors simultaneously during a calibration process in which the apparatus is moved through a predetermined pattern and/or a random pattern. Methods of calibrating using the apparatus are also disclosed.