Abstract: To provide a method for manufacturing an interdental cleaning tool that can prevent deformation of a core base at molding of a cleaning flexible part using an elastomer material, thereby effectively preventing occurrence of molding failure of the cleaning flexible part.

Abstract: Provided is prophylaxis cup for dentistry, comprising a first section storing a first medium, a second section storing a second medium, and one or more channels between the first section and the second section, wherein the first section, the second section and the one or more channels are adapted to allow the first medium and the second medium to be mixed, in response to a rotational movement of the prophylaxis cup. Provided also is a method for using prophylaxis cup in which the prophylaxis cup is positioned on a patient's tooth. A control is triggered to rotate the prophylaxis cup to cause a first medium stored in a first section of the prophylaxis cup to be mixed with a second medium stored in a second section of the prophylaxis cup. Provided further is a prophylaxis angle for dentistry, comprising a hand-piece, with the prophylaxis cup coupled to the hand-piece.

Abstract: An electric toothbrush with a thinner handle part to ensure the ease of manual tooth-brushing while improving the ease of a switch operation between the operating state and the stopped state, the electric toothbrush being configured to realize an effective oral cleaning by automatically giving a necessary mechanical assistance to a brush part according to the brushing state constantly varying during tooth-brushing depending on the cleaned part and the ways of holding and moving the toothbrush.

Abstract: A method and system for the fabrication of dental articles includes at least two imaging and measuring devices, which measure and provide images of the internal and external structure of intra-oral objects in a patient's oral cavity. The outputs from these devices are linked so that the descriptions of the intra-oral objects and features, oral cavity and surrounding bone structure are stored in a system of reference positions. The system of reference positions functions as a “global positioning device” registering locations and orientations of the measuring and imaging device or probe relative to the intra-oral objects and bone structure and orientations of the resulting individual frames or scans in the global system of coordinates. Three-dimensional images, scans and/or maps of the oral cavity obtained from each device are pieced together to generate solid three-dimensional models of the intra-oral objects.

Abstract: An exemplary virtual facebow system comprises a software program which is run on a tablet or other portable computing device with a microprocessor, an internal memory component, an image capture device, and a display screen. The virtual facebow system is used to record characteristics of the occlusal arch of a patient including, but not limited to, the midline of the patient's face, the steepness and cant of the occlusal arch, as well as a record of which maxillary (upper) teeth make contact with which mandibular (lower) teeth. The recorded characteristics are then used to replicate the alignment of the patient's occlusal arch with the maxillary cast in a lab stand, and the maxillary cast can then be moved to an articulator for the production of customized dental prosthetics for the patient including, but not limited to, restorations and partial or full dentures.

Abstract: In a tooth whitening method, a whitening composition is applied to at least one tooth. The whitening composition is maintained on the at least one tooth for a first time period. After the first time period, a light radiation is directed toward the at least one tooth for a second time period. The first time period has a duration greater than 50% of a total duration of the first and second time periods. The whitening composition is removed from the at least one tooth.

Abstract: A semen container fitted with a specialized tip includes a substantially hollow body having a sealable first end adapted for the introduction of biological fluids such as semen and a second end having a nozzle molded thereto. The nozzle terminates in a removable tip that is anchored to the container by way of a tab such that after dispensing the biological liquid from the container the tip and the container may be disposed of simultaneously thereby reducing or eliminating the need to separately collect the removed tips from the ground.

Abstract: The present invention provides a fixating means adapted for use in hernia repair surgeries in attaching a mesh and mesh deployment means; said fixating means are attached to said mesh deployment means; and fixating means comprising: (a) a first portion coupled to said deployment means; and, (b) a second portion comprising a coil having a predetermined retracted shape; said coil is reconfigurable from a plurality of unretracted positions to a plurality of retracted positions and from said plurality of retracted positions to said plurality of unretracted positions; wherein said attachment between said deployment means and said mesh is obtained by reconfiguration of said coil from at least one of said unretracted positions to at least one of said retracted positions.

Abstract: A surgical mesh includes a body portion configured to extend across a tissue defect and a plurality of fibers secured to the body portion. The plurality of fibers extends outwardly from the body portion and is gathered at a hub for handling by a clinician. In embodiments, the plurality of fibers may be coupled to the mesh via one of knitting, weaving, or interlacing each fiber through yarns forming the body portion. In other embodiments, the plurality of fibers is coupled to the mesh via one of knotting, tying, welding, adhering, and fusing each fiber to yarns forming the body portion.

Abstract: An improved embolic filter frame is provided. The filter frame provides enhanced longitudinal compliance, improved sealing, low profile delivery, and short deployed length. The looped support struts have high “radial” stiffness with low “longitudinal” stiffness. When deployed, the frame exerts a relatively high stress onto a vessel wall to maintain an effective seal, yet remains longitudinally compliant. Minor displacements of the support wire or catheter are therefore not translated to the filter. The looped support struts elongate when tensioned and assume a compressed and essentially linear form. When the delivery catheter constraint is removed, the struts “snap open” and assume a looped configuration, exerting a high degree of force onto the vessel wall, creating an enhanced filter to vessel wall seal.

Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.

Abstract: The invention relates to a medical apparatus including a device used in the treatment of weight loss, obesity and potentially other associated health problems, e.g., type II diabetes. The device is used to impede absorption of nutrients within the gastrointestinal tract, i.e., bypassing a portion of the gastrointestinal tract. The medical apparatus enables implantation of the device using minimally invasive techniques, such a transesophageal approach under visualization. The device may be implanted via a working channel of a medical scope, e.g., an endoscope or in combination with a medical scope.

Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).

Abstract: In order to provide an artificial blood vessel that can prevent formation of a thrombus and a method for producing the artificial blood vessel, an artificial blood vessel is used (i) in which a peptide including a specific amino acid sequence has been added to an extracellular matrix obtained from a bio-derived vascular tissue and (ii) whose lumen has a cross sectional diameter of 4 mm or less.

Abstract: A dilatation or fatigue tester for a stent-graft prosthesis includes a sample holder having a compressible member that defines a chamber for receiving a stent-graft prosthesis in an expanded state, a bearing assembly disposed to contact and act on an exterior surface of the compressible member of the sample holder, and an actuation assembly operably coupled to the bearing assembly for rotating the bearing assembly relative to the sample holder. Rotation of the bearing assembly cyclically compresses the compressible member of the sample holder to thereby provide cyclical radial loading and unloading of a stent-graft prosthesis received therein for simulating physiologic loading conditions of a stent-graft prosthesis within a vasculature due to a beating heart.

Abstract: The present invention relates to a breast prosthesis allowing controlled release of a drug and to a production method for same, and more specifically, relates to a breast prosthesis allowing controlled release of a drug by the coupling of a drug layer comprising particles carrying the drug on the breast prosthesis, and to a production method for same.

Abstract: Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

Abstract: Prosthetic capsular devices (e.g., bag, bowl, housing, structure, cage, frame) include technology devices such as a computer, virtual reality device, display device, WiFi/internet access device, image receiving device, biometric sensor device, game device, image viewers or senders, GPSs, e-mail devices, combinations thereof, and/or the like. The technology devices can be used in combination with an intraocular lens. The output from the technology device(s) can be fed to the retina of the user to provide a visual image, can be otherwise connected to the user, and/or can be used to control the properties of the intraocular lens or of the prosthetic capsular device.

Abstract: A prosthetic heart valve includes annularly spaced commissure portions, each of which includes a tip. The stent is formed from a polymeric material, and is specifically configured to perform similarly to conventional metal stents. A first fabric covers each of the tips, and a second fabric covers the first fabric and remaining exposed portions of the stent. A first layer of tissue covers the second fabric, and a second layer of tissue overlies the second fabric. The second layer of tissue includes leaflet portions that extend inwardly between annularly adjacent ones of the commissure portions.

Abstract: The invention provides a multi-component (modular) percutaneous valve device that includes a valve module having valve leaflets and a valve frame. The valve frame includes one or more, for example two, ring members and a plurality of masts. Also provided is a valve frame having specially designed pivot points at the connection between masts and first and second ring members to assist folding the valve module and minimizing delivery diameter. The valve frame may also include wire guides to facilitate combining the valve module with a support module. The masts or a ring of the valve frame may also include locking members, such as shafts for closing the valve module and securing the valve module to the support module. The support module includes corresponding locking members, such as spears that align with the shafts on the valve module for assembly and locking the valve module to the support module.

Abstract: An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.

Abstract: A catheter system configured to deploy a valve prosthesis can include a catheter tip at a distal end of the catheter system. The catheter tip can include a device holder releasably connected to and retaining the prosthesis. The catheter tip can also include a first housing portion that accommodates the first portion of the prosthesis, and a second housing portion that accommodates the second portion of the prosthesis. The first housing portion and the second housing portion are configured to move relative to one another such that the catheter system sequentially releases the prosthesis to an expanded state by uncovering the second portion of the prosthesis allowing the second portion of the prosthesis to expand.

Abstract: An elongated member and a method of manufacturing an elongated member may include first, second, and third elongated rod mandrels. The first, second, and third elongated rod mandrels may be fixed together at predetermined proximal and distal locations and at a ball tip. The first, second, and third rod mandrels may be disposed within a tubular coupling element and fixed to the tubular coupling element at the ball tip. The tubular coupling element may be placed into abutment with and fixed to the distal end of an elongated shaft.

Abstract: A device for transcatheter gathering of tissue of a heart valve leaflet may include an elongated tube extending in a longitudinal direction and having an open distal end, a tissue securing component disposed at the distal end of the elongated tube, and a capture tool movable in the elongated tube between a retracted position and an extended position. The elongated tube may have an inner surface and a lumen extending therethrough. The tissue securing component may include a clip having a roller and a support element. The roller may be rotatable relative to the support element. The capture tool may be operable to capture tissue of the heart valve leaflet and to draw the captured tissue into the tissue securing component. The tissue securing component may be adapted to be applied to the captured tissue to hold the captured tissue in a gathered configuration.

Abstract: A tool for implanting an inflatable penile prosthetic cylinder includes a pincher and a plunger coupled to a handle of the tool and movable relative to the pincher. The pincher has a spine portion that is movably coupled to a distal end portion of the handle and a first jaw movably coupled to a second jaw along the spine portion of the pincher. The first jaw has a first plunger edge that is spaced a gap distance away from a second plunger edge of the second jaw. The plunger is tapered having a first width at a distal end that is not greater than the gap distance and a second width that is larger than the first width. The second width measured proximal of the distal end of the plunger.

Abstract: The invention relates to a method for modification of a biocompatible component. The method of the invention includes the steps of a) providing a biocompatible component at least partly covered by metallic oxide; and b) treating at least a part of the component, which part is covered by the metallic oxide, with an aqueous composition that includes oxalic acid; whereby a modified metallic oxide, is obtained. The invention also relates to a biocompatible component-including a substrate having a surface with a) a microstructure including pits separated by plateus and/or ridges; and b) a primary nanostructure being superimposed on the microstructure, the primary nanostructure having depressions arranged in a wave-like formation.

Abstract: The present invention relates to an artificial hip joint replacement system. The system includes an acetabulum portion having a cup suitable to be received by a subject's acetabular bone. The cup includes a rigid portion and an elastic portion attached to the rigid portion. Also included in the system is a ball received within the cup and in contact with the elastic portion and a femoral stem attached to the ball. The elastic portion is positioned to cause expansion and allow contraction of a space between the ball and the rigid portion of the cup so they are further apart from one another during periods of low mechanical loads.

Abstract: An implant includes a fixed bearing, a floating bearing, and a coupling member. The fixed bearing defines a generally first spherical articulating surface and a stop. The floating bearing includes a second spherical articulating surface and a planar articulating bearing surface. The coupling member defines a bearing surface that translates relative to the planar articulating bearing surface.

Abstract: A knee prosthesis is provided that allows for increased flexion. The knee prosthesis includes (a) a femoral component adapted to fit on a distal end of the femur which includes a lateral condylar structure and a medial condylar structure and (b) an intermediate structure configured to cooperate with a femoral component of a knee prosthesis. The intermediate structure includes at least one surface for contacting the femoral component and a transition of a sagittal curvature of the at least one contact surface from a concave surface into a convex surface at the contact interface of the femoral component and the intermediate structure when the knee is flexed at approximately 120° to 140°. The knee prosthesis minimizes impingement on the femoral posterior cortex in deep flexion, increases the dislocation safety factor and allows for easier reengagement of the articular surface should the femoral component externally rotate off of the tibial plateau.

Abstract: Method and apparatus are disclosed for distracting tissue and particularly spinal tissue. The device and method may include insertion of at least one elongated member and an augmenting member to form a structure between the tissues to be distraction, such that a dimensional aspect of the structure is augmented upon movement of the augmenting structure.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: This prosthesis (1) includes two plates and an intermediate damping core (4) placed between both of these plates, this core (4) comprising a first shell (6) and a flexible element placed between this first shell (6) and a part for receiving the core. The first shell (6) and the first receiving part include means (18, 26) for guiding their mutual movement for bringing them closer or moving them away from each other. According to the invention, the receiving part includes a cavity intended to snugly receive the flexible element. The cavity being delimited by a first peripheral wall and by a bottom wall. The first peripheral wall having an external peripheral face; and the first shell (6) has a second peripheral wall forming an internal face. The internal face, when the first shell (6) and the receiving part are in their assembling condition, coming into close proximity to said external peripheral face and being able to slide along the latter.

Abstract: The invention is a spinal fusion system with fusion rod anchors which do not use staples or screws to achieve securement to a patient's spine. The system relies on a head segment pivotally attached to a base having a channel imparted therein, the channel having an entry and exit opening. The rod anchor is secured with a threadable segment which is threaded through the channel and around an associated vertebra. Multiple rod anchors can be attached to a patient's vertebrae in this manner and a fusion rod is inserted into the multiple anchors and locked down inside the rod anchors with a lock nut.

Abstract: An expandable implant device (100, 300, 600) for insertion between two vertebrae (400) is disclosed. The device (100, 300, 600) has a center body (10) one or more lift bodies (20, 40) and an external retaining band (60). The external retaining band (60) holds the sides (22, 42) of the one or more lift bodies (20, 40). The center body (10) has ramp surfaces (11) having a plurality or sets of ramps (11) sloped for allowing upward movement of the one or more lift bodies (20, 40). The sides (22, 42) have complimentary ramp surfaces that fit onto the ramps (11) of the center body (10). The height of the device (100, 300, 600) is increased by upward movement or downward movement or both of the one or more lift bodies (20, 40) driven by the lengthwise movement of the center body (10).

Abstract: A spinal implant having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions. At least one of the top surface and bottom surface has a roughened surface topography, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction generated when the implant is placed between two vertebrae and to inhibit migration of the implant. At least one of the top surface and the bottom surface also includes at least one self-deploying anchor having an expulsion tab and a bone-engaging tip that causes the implant to resist expulsion once the expulsion tab is deployed.

Abstract: An intervertebral insert member and an instrument for positioning the insert in a space between vertebral bodies in vivo. The insert member is advanced by the instrument into a prepared site located between adjacent vertebral bodies. Upon reaching the appropriate insertion point, the sleeve is retracted and a pivotal motion is imparted to the insert. The insert member is pivotally attached to the distal end of the delivery instrument such that it can be articulated about a pivot point that is located on the insert member until it is properly positioned. The positioning instrument is then released from the insert member and removed from the space between the vertebral bodies. An adjustment screw is available to expand the surfaces of the insert member by displacement of a wedge member within the insert.

Abstract: An instrument for insertion and positioning of a spinal implant includes an outer member, an inner member, and a first thread. The outer member includes a distal attachment feature configured to engage with the spinal implant, a tubular member, and a proximal housing. The inner member is rotatably disposed within a lumen of the outer member and includes a distal coupling feature for coupling with a proximal end of the spinal implant, an elongated shaft within the tubular member, and a proximal end operably coupled with a handle that rotates relative to the proximal housing. The first thread is disposed on the distal coupling feature and includes a first lead and a first thread pitch greater than a thickness of the proximal end of the spinal implant.

Abstract: A depth gauge and method provide for accurate measurement of a socket portion of a bone tunnel in an ACL reconstruction.

Abstract: The present invention relates to joint simulators, and in particular, to methods and systems for controlling joint simulators by using a haptic mapping technique. A joint simulator is used to closely approximate the conditions within the body, particularly with respect to human and animal joints, and can be used to test and evaluate prosthetics for use in various parts of a human or animal body. The haptic mapping technique improves the rate of convergence of the actual testing forces to the prescribed forces during repetitive performance and life testing. The method is used in conjunction with an impedance-mode servo controller.

Abstract: Apparatus and methods are described including an implantable device having first and second longitudinal ends, the device having a length of less than 80 mm when the device is unconstrained. The device includes struts arranged such that, when the device is unconstrained, along a continuous portion of the device having a length that is at least 5 mm, a maximum inter-strut distance defined by any set of two adjacent struts is more than 1.5 times as great as a maximum inter-strut distance defined by any set of two adjacent struts within longitudinal portions of the device within 3 mm of the longitudinal ends of the device. Other applications are also described.

Abstract: The application provides customized aortic stent and stent graft devices and methods for the manufacture thereof. The customized aortic stent or stent graft are patient-specific in that they conform to at least part of the ascending aorta, aortic arch and/or thoracic aorta.

Abstract: A stent for placement in a body lumen is fabricated by forming a tube having an undeployed diameter sized for the tube to be placed on a deployment balloon and advanced through a body lumen to a deployment site. The tube is expandable upon inflation of the balloon to an enlarged diameter sized for the tube to be retained within the lumen at the site upon deflation and withdrawal of the balloon. The tube has a stent axis extending between first and second axial ends of the tube. The tube has an exterior surface and an interior surface. The tube is polished to polish the exterior surface to a smooth surface finish and with at least a portion of the interior surface having a rough surface finish rougher than the surface finish of the exterior surface.

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

Abstract: Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold structure has patterns that include an asymmetric or symmetric closed cell, and links connecting such closed cells.

Abstract: A degradable polyester stent is disclosed, which includes a polyester composite, wherein the polyester composite is produced from a biodegradable polyester and a metal-based material. A method of preparing the degradable polyester stent is also disclosed. The method can improve the mechanical properties of the biodegradable copolymer stent and can achieve the radiopacity of the main body and the overall of the stent.

Abstract: A stent graft for placement in a lumen of a patient is disclosed. The stent graft comprises: a main tubular body of a biocompatible graft material having a main lumen, the main tubular body having a proximal end and a distal end; a side arm extending from the main tubular body, the side arm having a side arm lumen, the side arm lumen being in fluid communication with the main lumen through a side arm opening in the main tubular body; and a cannulation pocket. The pocket comprises: an exit aperture positioned opposite the side arm opening; an entry aperture longitudinally spaced from the entry aperture in a direction toward the distal end of the main tubular body; and a wall, the wall laterally spaced from the main lumen so as to provide a guide surface for a cannula fed through the entry aperture.