Abstract: A medical pacifier for supplying gases such as oxygen, nitrous oxide or albuterol to the user, with the novel feature of a control valve included in the pacifier to allow the operator to direct the flow of the gas to the oral cavity, the nasal area, or both the oral cavity and nasal area of the user.

Abstract: A method of removing a dental adhesive may comprise locating the position of the dental adhesive, directing radiant energy into the dental adhesive causing the dental adhesive to weaken a bond formed with the dental adhesive, and breaking the bond by applying a suitable force to overcome the weakened bond. A dental adhesive may comprise a polymer and a dye or pigment, The dental adhesive may be formulated to cure to form a bond that is weakened in response to the dye or pigment absorbing radiant energy subsequent to curing.

Abstract: Monomer mixture for the preparation of dental materials, which contains at least one low-volatile monomethacrylate, at least one highly viscous polyfunctional methacrylate and at least one low-viscosity polyfunctional methacrylate.

Abstract: Provided is a fluoroaluminosilicate glass powder that can provide a dental glass ionomer cement hardened body excellent in acid resistance, the glass powder including sodium and potassium which have an effect of lowering the reflective index of glass. A mass ratio of potassium to sodium in the component is in the range of from 1.2 to 1.9 in terms of oxide.

Abstract: Disclosed herein is an orthodontic cement having an effective polymerizable antibacterial resin that is capable of balanced antibacterial effectiveness, prevention of white spot lesions during orthodontic treatment, and excellent adhesion properties. Disclosed is a method and orthodontic cement composition comprising polymerizable antibacterial/antimicrobial monomers, and a high performance orthodontic cement formulated from such novel bioactive resins.

Abstract: Non-spherical liquid droplets comprising a liquid, an internal solid material defining the shape of the droplet, a benefit agent, and methods of making non-spherical liquid droplets.

Abstract: A formulation starts as a gel and transforms into a foam under influence of light and heat to expand out into the oral cavity of a user for advantageous health benefits. A closed system mouthpiece includes light and heat generation to activate the formulation to increase its volume. Application of heat above a threshold temperature causes the gel to transform into foam and expand out of the mouthpiece and into the oral cavity. With the foam so dispersed within the oral cavity, activation of a light source embedded within the mouthpiece enhances the bacteria killing properties of the now foam material. The foam spreads onto the tongue of the user as well and acts to kill any damaging bacteria found there. As a result, the pH balance of the mouth is restored to a neutral level in the range of 6.75 to 7.25 or maintained at that pH level.

Abstract: The instant invention relates to a composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding the core, and the encapsulated material being at least one particle having a high wet point and being optionally porous, and being only released from the microcapsule when the composition is applied onto a keratin material, such as keratin fibers or skin. The invention further relates to a method for preparing the composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding the core, and the encapsulated material being at least one particle having a high wet point and being optionally porous, and being only released from the microcapsule when the composition is applied onto a keratin material, such as keratin fibers or skin.

Abstract: A solid particle ranging from 0.001 to 200 microns in diameter coated with Indium Nitride (“IN”) and a topical composition containing same as well as a method for protecting skin against IR radiation.

Abstract: Provided is a single phase oral care composition having a whitening agent; a first abrasive selected from calcium pyrophosphate, calcium carbonate, and dicalcium phosphate; a second abrasive that may include sodium metaphosphate; an anticalculus agent; and a substantially anhydrous carrier that may include an ethylene oxide/propylene oxide copolymer. In the composition, a wt % of the second abrasive is equal to or greater than a wt % of the first abrasive.

Abstract: Cosmetic compositions including a) 0.05 to 10% by weight of a hydrophobized metal oxide powder, b) 0.01 to 2.0% by weight of at least one white pigment, c) 1.0 to 50% by weight of wax, d) 1.0 to 30% by weight of an emulsifier, e) 0.1 to 25% by weight of an organic polyol, and f) 5.0 to 90% by weight of water, the use thereof for temporary hair shaping, and a method using these compositions.

Abstract: A non-alcohol mouthwash composition includes: a sweetener, a dispersing agent, a surfactant, an antimicrobial agent, a calcium ion source including calcium lactate, a phosphate ion source including monobasic sodium phosphate, a flavoring agent, a fluoride source, and water. The non-alcohol mouthwash composition includes about 0.001 weight percent of the calcium lactate and about 0.10 weight percent of the monobasic sodium phosphate, based on total weight percent of the non-alcohol mouthwash composition, and the composition has a pH greater than about 5.5.

Abstract: An dual oral composition is provided having a first peroxide-containing component and a second bicarbonate-containing component having exceptional anti-plaque and anti-bacterial action with re-mineralization properties.

Abstract: The process of the invention provides for a preventive hair treatment with buffering agent, in particular glyoxylic acid in combination with mechanical straightening with hair straightening iron at temperature of approximately 200° C.+/?50° C.

Abstract: Peptides, topical compositions, and methods of improving health and/or appearance of human integuments, such as keratinous surfaces and fibers are provided. The peptides have from 3-12 amino acid residues and comprise the sequence YNT (SEQ ID NO: 1) or PVG (SEQ ID NO: 2).

Abstract: The present invention provides a composition for inhibiting hair production in a mammal comprising an active polypeptide component and a pharmaceutically acceptable and/or cosmetically acceptable excipient, carrier or diluent. The invention further provides methods of inhibiting hair production in a mammal, e.g. human.

Abstract: Surprisingly, it has now been found that, when a hair care agent including at least one casein hydrolysate is applied, the hair growth itself and thus also the structure, elasticity, strength, resistance, and shine of the keratin fiber are significantly improved. Furthermore, is has surprisingly been found that the compositions according to the invention are suitable for triggering the release of growth factors and for strengthening and thickening the hair by stimulating the proliferation of the hair keratinocytes. The stimulation of the keratinocytes of the outer root sheath, which are partly responsible for the formation of the hair shaft, occurs by means of the growth factors HGF and KGF. Effects such as the “overconditioning” of the hair are avoided by means of the biologically based hair thickening. The hair grows more intensely from the root on and with a larger diameter, so this effect is particularly long-lasting.

Abstract: Provided are methods of treating skin with at least two alternating treatment modalities to improve the health and/or diminish signs of aging. Some methods according to the present invention may comprise topically applying at least two separate compositions, in a sequential, rotating, or alternating fashion to overcome adaptation, tolerance, or sensitization phenomena.

Abstract: A tocopherol phosphoric acid ester represented by a following formula (1) (in the formula, R1, R2, and R3 each independently represents a hydrogen atom or a methyl group,), a pharmacologically-acceptable salt thereof, or a solvate thereof for use in the improvement of skin color.

Abstract: The present invention provides a cationic arabinoxylan and the hydrophobically modified product thereof. The cationic arabinoxylan is prepared based on a cereal arabinoxylan and a quaternizing agent, with water as solvent and strong alkali as catalyst. The hydrophobically modified product is prepared based on cationic arabinoxylan and alkyl halide, with pyridine as catalyst. Said cationic arabinoxylan and the hydrophobically modified product thereof can be used as a conditioning agent or thickener in cosmetics or personal care compositions, and can also be used in textile, papermaking, pharmaceutical and food industry applications.

Abstract: A volatile oily composition includes from 50 to 100% by weight of a mixture of paraffins and from 0 to 50% by weight of at least one non-volatile oil. Cosmetic compositions containing the abovementioned oily composition, and the cosmetic uses of the cosmetic compositions, particularly for making up and/or caring for and/or protecting skin, lips, eyelashes and/or nails, and in antiperspirant/deodorant compositions are also described.

Abstract: The invention relates to agents for cleaning and/or caring for damaged keratin fibers, including a combination of at least one dicarboxylic acid having 2 to 10 carbon atoms and at least one selected amino acid, and a method for cleaning and/or caring for keratin fibers by means of such agents.

Abstract: The application relates to oral care compositions comprising substantive polyesters formed from xylitol, polycarboxylic acids (or esters, acid halides or anhydrides thereof) and optionally arginine. The formed polyesters or polyesteramides are active in biofilm inhibition and dissolution to maintain clean teeth.

Abstract: Provided are compositions that are useful as oil-free emollients in personal care formulations. The emollients are oil-soluble polyalkylene glycols, wherein the polyalkylene glycol comprises units derived from propylene oxide and units derived from butylene oxide, and in certain embodiments are compounds of Formula I: RO-(PO)n-(BO)m-H??(I) wherein PO is propyleneoxy, BO is butyleneoxy, R is a linear or branched C8-C20 alkyl, n has an average value of from 5 to 20, and m has an average value of from 4 to 16.

Abstract: A hair treatment method sets a hair style and/or its restyling comprising application of an anhydrous spray on wet hair. The method treats hair by applying a substantially anhydrous composition, comprising one or more polymers according to the general structure wherein A is a C2 to C6 alkylene group and n represents an average number of 5 to 1000 and p represents an average number of 5 to 100, onto wet hair.

Abstract: Cosmetic compositions including, based on their total weight, a) 10 to 90% by weight of a hydrocarbon or hydrocarbon mixture with a melting point between 38° C. and 58° C., b) 1.0 to 45% by weight of a silicate from the group of phyllosilicate and aluminosilicate, c) 0.01 to 7.0% by weight of a hydrophobized metal oxide powder, d) 0.01 to 3.0% by weight of at least one white pigment, e) 3.0 to 15% by weight of wax, f) 0.5 to 15% by weight of an emulsifier, and g) less than 3.0% by weight of water the use thereof for the temporary shaping of keratinic fibers, and a method using these compositions.

Abstract: The present invention relates to an anhydrous composition comprising: from 3% to 15% by weight of at least one lipophilic gelling agent; from 20% to 50% by weight of at least one filler chosen from spherical porous silica particles, spherical cellulose particles and powders of an N-acylamino acid bearing a C8-C22 acyl group; and from 40% to 85% by weight of at least one fatty phase containing at least 20% by weight of at least one oil chosen from hydrocarbon-based oils of plant origin, preferably triglycerides, Guerbet alcohol derivatives, preferably Guerbet alcohols and esters of a fatty acid and of a Guerbet alcohol, fatty alcohol ethers comprising from 6 to 20 carbon atoms, and linear alkanes comprising from 7 to 17 carbon atoms; the weight amounts being given relative to the total weight of the composition. The composition in accordance with the invention affords comfortable anhydrous care with a soft-focus effect, i.e.

Abstract: The present specification discloses a composition comprising a Scutellaria alpina extract as an active ingredient. The composition disclosed in the present specification exhibits the effect of reducing melanogenesis or inhibiting tyrosinase activity by comprising the Scutellaria alpina extract. As a result of the effect, the Scutellaria alpina extract of the present specification can exhibit a whitening effect and thus can be widely used as a whitening composition in the field of pharmaceuticals or cosmetics.

Abstract: A method of treating a medical condition resulting from a tattoo has the steps of cleaning at least one surface of the tattoo; preparing a plurality of needles to administer a formulation of a solution containing aloe, less than about 30% salt, carboxymethylcellulose and distilled water; covering the surface of the tattoo surrounding area with injections of the solution until the selected area has a different appearance; spreading the solution on the surface of the tattoo to provide a coating, and permitting the solution to dry. Preferably the salt is Himalayan salt.

Abstract: A kit for preparing a customized cosmetic includes at least one of five cosmetic bases. Each of the five cosmetic bases correspond to at least one of a plurality of primary categories. The kit additionally includes at least one cosmetic active ingredient for admixing with the at least one cosmetic base. The at least one cosmetic active ingredient corresponds to at least one of the plurality of primary categories or at least one of the plurality of secondary categories.

Abstract: The present invention relates to chewing gum containing a synergic combination of zinc and vegetable extracts containing polyphenols. Said chewing gum is useful in treating the symptoms of halitosis.

Abstract: The present invention teaches compositions, methods and kits for treating skin conditions, including dandruff. In various embodiments, the compositions include an effective amount of one or more probiotic microorganism of vaginal origin and/or a fraction thereof and/or a component of the metabolome for preventing and/or treating skin disorders of the scalp.

Abstract: Aspects of the present invention provide stable liquid ready-to-use injectable formulation of bortezomib or pharmaceutically acceptable salts thereof. Another aspect of the present invention provides processes for preparation of such stable liquid ready-to-use injectable formulation of bortezomib and methods of using such formulations for treating various types of cancers in mammals.

Abstract: The present invention concerns an orodispersible self-supporting film free from hydrocolloids comprising: a) a film-forming substance consisting of a maltodextrin in an amount comprised between 40 and 80% by weight; b) one or more plasticizer in a total amount comprised between 15 and 55% by weight; e) a surfactant System in an amount comprised between 0.5 and 6% by weight; d) an active ingredient for food or therapeutic use in an amount between 0.05 and 30% by weight, said orodispersible self-supporting film free from hydrocolloids further containing a homopolymer or a copolymer of vinyl acetate in a quantity comprised between 1 and 20% by weight where the percentages are calculated on the total weight of said film.

Abstract: The present invention is directed toward respirable dry powders and particles for systemic delivery of pharmaceutically active agents or delivery to the respiratory tract. The dry powders contain one or more monovalent metal cations (such as Na+), are small and dispersible.

Abstract: The present invention relates to a novel process used for the preparation of dry powder formulations for inhalation.

Abstract: The present invention relates to a novel process used for the preparation of dry powder formulations for inhalation.

Abstract: Accordingly, the present invention provides a pharmaceutical oil-in-water nano-emulsion, with a pharmaceutically active substance. The selected pharmaceutically active substance is encased in monounsaturated fatty acid droplets with the droplets having an average particle size in the range of 60 to 200 nm. The nano-emulsion is also provided with a non-ionic surfactant system, which is a mixture of polyethers, macrogolglycerides and polysaccharides, along with pharmaceutically acceptable adjuvants. The present invention also provides a process for the preparation of pharmaceutical oil-in-water nano-emulsion.

Abstract: The present application relates to a micelle comprising a drug encapsulated by an amphiphilic polymer and a composition comprising the same. The micelle of the present application has an excellent dispersion property on an aqueous solution and a superior percutaneous absorption characteristic on preparing a formulation.

Abstract: The present invention relates to a composition comprising liposomes, water, and one or more solidifier(s), wherein said solidifier(s) form(s) a solid matrix in which said liposomes are embedded, and is/are contained in the inner lumen of said liposomes. The present invention further relates to a method for the production of respective compositions.

Abstract: Provided herein are compositions and methods for treating cancer in a subject in need thereof. The methods include using hybrid polymerized liposomal nanoparticles comprising, both polymerizable lipids and non-polymerizable lipids. The nanoparticles further comprise targeting agents and therapeutic agents.

Abstract: The invention features a cationic lipid of formula I, an improved lipid formulation comprising a cationic lipid of formula I and corresponding methods of use. Also disclosed are targeting lipids, and specific lipid formulations comprising such targeting lipids.

Abstract: A process for the production of particles comprises the steps of formation of a solution of a desired substance in a suitable solvent; ii) generation of an aerosol from the solution of said substance; iii) collection of the aerosol droplets in a vessel containing a non-solvent of said substance; and iv) the application of ultrasound to the droplets dispersed in the non-solvent to effect crystallisation of said substance. The particles produced find application in for example pharmaceutical and agrochemical formulations, especially in inhalation formulations.

Abstract: The present invention provides nanoparticles and a method of preparing the nanoparticles by using an ice template. Pharmaceutical formulations including such nanoparticles and their use are also described. The method allows for an environmentally friendly provision of advantageously small particles with higher production rate and improved reproducibility.

Abstract: The present invention relates to pharmaceutical composition, comprising certain phosphate binder particles having a certain particle size distribution, a process for the manufacture of the pharmaceutical composition and the use of sucroferric oxyhydroxide having a certain particle size distribution for the manufacture of a pharmaceutical composition.

Abstract: Effective methods and compositions to deter abuse of pharmaceutical products (e.g., orally administered pharmaceutical products) including but not limited to immediate release, sustained or extended release and delayed release formulations for drugs subject to abuse comprising at least 10% by weight hydroxypropylcellulose; polyethylene oxide; and a disintegrant selected from the group consisting of crospovidone, sodium starch glycolate and croscarmellose sodium; wherein the ratio of hydroxypropylcellulose to polyethylene oxide on a weight basis is between about 10:1 and 1:10.

Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.

Abstract: Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse by ingestion of multiple individual doses. In addition, the disclosed dosage forms provide protection from overdose in the event of accidental or intentional ingestion of multiple individual doses.

Abstract: A method and composition are provided for coating a component to achieve colon-targeted delivery. A component is coated with a fructose-based non-digestible carbohydrate such as a inulin, fructo-oligosaccharide or neosugar. The coated component is orally administered to a monogastric animal. The non-digestible coating causes the composition to pass through the stomach and small intestine without being degraded, and delivers the component to the colon where the coating is digested by microbial fermentation and the component is released.

Abstract: A layer-by-layer (LbL) system, which alternately ionically complexes anionic AuNPs to two unique cationic polymers (disulfide-reducible and hydrolytically degradable) and two anionic nucleic acids, is disclosed.