Abstract: Disclosed herein are fluid handling devices that include integrated card and pipette tip devices, for use with multichannel liquid dispensing devices.

Abstract: Systems, methods, and compositions are provided for low volume liquid handling.

Abstract: According to embodiments of the present invention, a microfluidic chip, a manufacturing method therefor and an analysis device using the same are provided. The microfluidic chip comprises: a substrate comprising an inflow part through which a fluid flows in, a fluid channel through which the fluid moves and an outflow part through which the fluid flows out; and a film attached to the substrate to protect at least one of the inflow part, the outflow part and the fluid channel from the outside, wherein the inflow part and the outflow part are implemented by penetrating through the surface of the substrate, and the fluid channel can be implemented by being sunk from the surface of the substrate.

Abstract: The present invention relates to systems and methods for monitoring the amplification of DNA molecules and the dissociation behavior of the DNA molecules. A method according to one embodiment of the invention may include the steps of: forcing a sample of a solution containing real-time PCR reagents to move though a channel; and while the sample is moving through an analysis region of the channel, performing the steps of: (a) cycling the temperature of the sample until the occurrence of a predetermined event; (b) after performing step (a), causing the sample's temperature to gradually increase from a first temperature to a second temperature; and (c) while the step of gradually increasing the sample's temperature is performed, using an image sensor to monitor emissions from the sample.

Abstract: A flow cell having at least one storage zone connected to a duct for conducting fluid out of, into or/and through the storage zone. The duct includes a duct section which is delimited by a substrate and a film joined to the substrate and in which the duct is sealed and can be opened at a predetermined breaking point by deflecting the film. The film covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall which is formed in the edge portion and runs parallel to the film determine the surface area of the joining region.

Abstract: The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are unable to pass through a narrower passageway bounded by a segregating step, resulting in segregation of the particles. The breadth of the leading edge of at least one step of the apparatus is significantly greater than the overall width of the passageway in which the step occurs, permitting high and rapid sample throughput. The apparatus and methods described herein can be used to segregate particles of a wide variety of types. By way of example, they can be used to segregate circulating tumor cells from a human blood sample.

Abstract: A system and method for isolating and analyzing single cells, comprising: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.

Abstract: The present disclosure relates to a reagent storage device and a bio-reaction apparatus including the same. Provided is a reagent storage device connected to a biochip to provide reagents into the biochip. The reagent storage device includes a storage container having a tube shape of which one end is opened, and the other end opposite to the one end is closed and a plurality of diaphragms provided in the storage container and installed to be closely attached to an inner wall of the storage container. Here, the diaphragms are spaced apart from each other in one direction in which the one end and the other end are disposed opposite to each other, and each of the diaphragms includes a through-hole passing therethrough.

Abstract: Systems and methods for low voltage power thermal cycling are provided. A nucleic acid amplification device comprising a thermal cycler and a detector is capable of operating using a low operating voltage, such as 12 V. The nucleic acid amplification device may include a portable energy storage device that can provide operating power. The nucleic acid amplification device may be powered by a vehicle and deployed to remote locations.

Abstract: The present invention relates to an ultra-high speed real-time PCR device on the basis of a lab-on-a-chip for detecting bacteria that causes food poisoning pertaining to agricultural food and a food poisoning detection method using the same. The present invention can provide a micro PCR chip which can simultaneously accommodate a plurality of small-volume samples and concurrently secure maximum thermal contact efficiency with a heating block so as to secure rapid results, and accurately measure an optical signal emitted from a nucleic acid amplification product even without any separate filtering or processing. Further, on the basis of the PCR chip, the present invention can provide a real-time PCR device which can rapidly obtain a nucleic acid amplification result of which the reliability is secured even without a complicated light-signal measuring module.

Abstract: A mating adaptor for use in assaying a specimen includes an adaptor body having a first receiving area for receiving a computing device and a second receiving area for receiving a specimen delivery cartridge. The mating adaptor further includes an actuator for transmitting a mechanical actuation signal to initiate a fluidic process of a specimen delivery cartridge. The first receiving area includes a first connector corresponding to a computing device connector and the second receiving area includes a second connector corresponding to a specimen delivery cartridge connector.

Abstract: The transmission holder according to the invention for a roller press has a two-part structure with a transmission part which is connected to the transmission and a separate torque supporting part which is to be connected to the machine base frame or foundation. Transmission and torque supporting part of the transmission holder can be detachably connected to one another, preferably by means of a screw or bolt connection. In one embodiment this connection has two screws or bolts. Advantageously the dismantling or assembly of the rollers can thus be accomplished significantly more simply than according to the prior art since merely the screw or bolt connection between transmission and transmission holder of the transmission holder must be released. Advantageously significantly fewer screws/bolts need to be released for dismantling the transmission which in addition are more readily accessible and have a significantly greater distance from one another than according to the prior art.

Abstract: An apparatus and a method for performing maintenance on grinding discs are disclosed. The apparatus can be positioned below the housing of a vertical grinding mill and attached to the housing in order to provide temporary support for grinding discs when the grinding discs are removed from the housing. The apparatus can be rotated so that it is in a longitudinal position when the grinding discs are within the housing.

Abstract: A shearing device for fragmenting a metal strip includes two counter-rotating drums facing one another, a drive device connecting the drums and synchronising their rotation speed, and at least one pair of drum-supported blades. The blades engage by shearing effect during drum rotation to cut the waste. The blades of the pair have, from the cutting edge thereof, planar surfaces, referred to as overlapping surfaces, overlapping and facing one another during the shearing between blades, each blade being secured transversely to the drum, at an angle to the axis of rotation of the drum, so the plane through the overlapping surface of the blade forms an angle with the axis of rotation of the corresponding drum, producing gradual shearing. The overlapping surface of each blade is tilted so the plane passing through the overlapping surface does not intersect the rotational axis of the drum on its active width.

Abstract: The invention relates to a device for fixing and aligning cutter blades for a system for fine comminution and/or for emulsification of semisolid, plastic or plastoelastic substances, in particular raw substances for food production, comprising means for the detachable fastening of the cutter blades (3) to a cutter drive shaft (4). Furthermore, according to the invention, a single-part or multi-part support or carrier body (6) is provided which extends under or over the cutter blades (3) and which is connected, radially at the inside, to the cutter drive shaft (4), wherein a positively locking and/or non-positively locking connection is formed at least radially at the outside between the associated end of the support or carrier body (6) and the respective cutter blade (3).

Abstract: Methods and systems for processing incineration byproduct from waste incinerators, ash purification and recovery of materials and metals. High levels of aggregate and metals recovery and ash purification are achieved for residual ash with reduced environmental contaminants.

Abstract: A water separator comprises an axially extending airflow passage, an airflow mixer, a plurality of electric plates of alternating charge, and a mechanical separator. The airflow mixer, the plurality of electric plates, and the mechanical separator are disposed within the airflow passage. The airflow mixer imparts a non-axial flow component on airflow through the airflow passage. The electric plates are situated downstream of the mixer, and create an electric field region within the airflow passage. The mechanical separator is situated at or downstream of the electric field region, and is disposed to separate water droplets from air.

Abstract: Embodiments of the invention involve the application of a disk-in-tube type of “wet” or “dry” ESP (electrostatic precipitation) technology for the capture/removal of airborne particles entering a gas turbine compressor. This provides an effective method of particulate removal without the inefficiencies associated with conventional filtering techniques. Embodiments of the innovative approach also eliminate the inlet airstream blocking effect of a conventional filter, thus making its use and operation adaptable to different operating environments and processes that require clean input air streams (including industrial manufacturing processes, power generators, combined turbine and fluid recapture systems for use in heating and cooling, etc.).

Abstract: A high voltage power supply for an electrostatic precipitator comprises a high voltage transformer, a high voltage bridge rectifier and a semiconductor switch controller configured to control an output power level of the high voltage power supply. A control unit (50) is configured to determine a firing angle of firing pulses for the semiconductor switch controller. During normal operation, a peak voltage value is measured and stored in each half period. When a breakdown is detected, a residual voltage (Ur) over the electrostatic precipitator is measured. A firing angle (?1) of a firing pulse to be provided to said semiconductor switch controller in the first half period after the breakdown is determined from the latest stored measured peak voltage value (Ubef) and the measured residual voltage (Ur) based on a predetermined relationship between the firing angle (?1) and said measured voltages.

Abstract: A water nozzle with a flow head is provided with at least two separate water supply devices that supply, in a controllable fashion, different water volume flows to the flow head. The flow head generates an annular jet from the different water volume flows. By controlling the water volume flows, alternatively a slim annular jet or a widened annular jet is generated by the flow head. A deflection element with a central outlet opening is provided, wherein the central outlet opening is arranged in a flow direction of the annular jet downstream of and spaced apart from the flow head. A deflection device surrounds the central outlet opening. A diameter of the central outlet opening is designed such that the slim annular jet is able to pass through the central outlet opening while the widened annular jet impacts on the deflection device surrounding the central outlet opening.

Abstract: A coating apparatus for forming a coating film over a substrate includes a spin chuck for holding and rotating the substrate, a central coating nozzle over a central portion of the substrate, a plurality of first coating nozzles surrounding the central coating nozzle and spaced apart from the central coating nozzle by substantially a same first distance, and a plurality of second coating nozzles surrounding the central coating nozzle and spaced apart from the central coating nozzle by substantially a same second distance, wherein the second distance is greater than the first distance.

Abstract: The present invention is an anti-drip showerhead which includes a body, a cover plate and a plurality of spray outlets opened on the cover plate. Each of the spray outlets comprises an anti-drip means chamber at a first end and at least one spray outlet opening at a second end opposite the first end; the anti-drip means chamber and the spray outlet opening are in water communication with each other; each of the anti-drip means chambers is disposed with a water pressure actuated anti-drip means which is operable between an open position where water from the body is allowed to pass through the anti-drip means and exits through the spray outlet opening and a close position where water from the body is blocked by the anti-drip means and thus could not exit through the spray outlet opening.

Abstract: The invention relates to a shower head comprising a shower base body (2?) and a jet disk structure (3) disposed on the shower base body. With the shower head according to the invention as claimed the jet disk structure (3) includes a plurality of jet disk elements (4). The jet disk elements are individually and detachably fixable to the shower base body (2) and each form a partial jet disk surface (5) of a total jet disk surface. Furthermore, the shower base body has a distinct fluid supply (7) for each of the jet disk elements. Use, e.g., as a shower-bath shower head, in particular for an overhead, hand-held and/or side shower, for providing a water jet.

Abstract: A dispenser comprises a housing defining at least three feed channels, a spool valve with a spool defining at least three flow passages, a deformable sealing plug in at least two of the feed channels and in sealing orientation with both the housing and the spool, and a nipple in at least the two feed channels of the housing comprising sealing plugs; wherein the spool can reversibly rotate between an open orientation and a closed orientation can dispense two-component form formulations that are free of gaseous blowing agents.

Abstract: Disclosed is a pump dispenser (100) comprising: a body (110) defining a hollow interior (113) and an opening (114) through which at least a portion of a refill cartridge (10) containing a flowable substance is receivable into the hollow interior (113); a lid (120); and a pump for pumping the flowable substance from the refill cartridge (10) when the portion of the refill cartridge (10) is in the hollow interior (113) and the lid (120) closes the opening (114). The lid (120) comprises a dip tube (126) with a lumen (127) fluidly connected to the pump, the dip tube (126) has a tapered end (126A) located in the hollow interior (113) when the lid (120) closes the opening (114). At least one of the body (110) and the lid (120) has a grip on an exterior surface thereof for aiding relative movement of the body (110) and the lid (120) to access the hollow interior (113) when the lid (120) closes the opening (114). Also disclosed is a system comprising the pump dispenser (100) and the refill cartridge (10).

Abstract: Disclosed is a container for a pump dispenser, the container comprising: a body defining a chamber for storing a product and defining an opening at a first end of the chamber through which the product is dispensable from the chamber; and a protrusion extending from the body into the chamber at a second end of the chamber opposite from the first end of the chamber, the protrusion having a sharp distal end in the chamber. Also disclosed is a refill container comprising a body enveloping a cavity storing an oral, personal or home care composition, wherein the composition comprises water in an amount of less than 98% by weight, based on a total weight of the composition.

Abstract: Dispenser pump for pumping reservoir fluid to a dispenser head, has a dip tube to insert into the fluid, a cylinder housing connected with the dip tube, a piston pipe guided in longitudinal direction by the cylinder housing for pumping the fluid from the dip tube to the dispenser head, wherein the piston pipe comprises a connecting area for connecting the dispenser head to the piston pipe, a top part connected with the piston pipe, a bottom part connected with the cylinder housing and a spring bellow for pushing the piston pipe in a direction outwards the cylinder housing, wherein a lower axial end of the spring bellow is connected with the bottom part via a lower retainer ring located inside the spring bellow and/or a higher axial end of the spring bellow is connected with the top part via a higher retainer ring located inside the spring bellow.

Abstract: A trigger head for a dispensing device for at least two substances including a pumping system to compress the substances separately and simultaneously before dispensing.

Abstract: The invention relates to a device and a method for the metallic coating of a work piece with a mobile coating lance (20), by means of which a metal plasma jet can be generated to create the coating consisting of metal particles. According to the invention, an extraction hood (30) is provided, which at least encloses an axial section of the coating lance (20) in a ring-shaped manner, and the extraction hood (30) has a ring-shaped holding unit (50), which is configured to take up the metal particles.

Abstract: An on-wall shower system that is configured to be retrofit to existing in-wall shower plumbing. To assist in installation, the on-wall shower system provides for adjustability of an upper amount, for adjustably of a lower mount, and/or for axial height adjustment.

Abstract: [Problem] To provide a shower head capable of providing a shower feeling without a water spray plate, and configured to effectively generate micro bubbles, provide a shower feeling, and easy to hold.

Abstract: A high pressure nozzle manipulator includes a wheeled chassis, a pair of parallel manipulator elevator rails supported by an elevator rail rotator fastened to the chassis, a horizontal extensible arm rail disposed between and carried by the manipulator elevator rails, a rotary actuator fastened to a distal end of the horizontal extensible arm rail, and a linear actuator fastened between the first rotary actuator and a hinged nozzle support bracket. This bracket holds a high pressure cleaning nozzle. The linear actuator is configured to rotate the nozzle and the bracket through an arc. The elevator rail rotator is configured to rotate the elevator rails through an arc of about 180 degrees about a horizontal axis. The rotary wrist actuator is configured to rotate the hinged nozzle support bracket about a horizontal axis through the extensible arm rail.

Abstract: The invention relates to an applicator for applying a photocurable composite material over a large surface of a component, having a reservoir for the composite material and at least one lamp for curing the photocurable composite material, and according to the invention—the reservoir comprises at least one discharge region for the photocurable material, through which the photocurable material can be supplied to an applicator elements;—the applicator element is opaque to the light emitted by the lamp;—the photocurable material can be applied to the surface or spread on the surface of the component by contact of the applicator element with the surface. The invention further relates to an applicator element for an applicator, having at least one lamp and designed like a nozzle, the applicator element applying the photocurable material to the surface and/or spreading the photocurable material on the surface of the component by contact with the surface.

Abstract: A method for dispensing fluid from a fluid dispensing apparatus. The apparatus may include a housing, wherein the housing may include a motor, and wherein the motor may be configured to be operatively connected to a power supply, wherein the motor may be further configured to be operatively connected to one or more drive rods, wherein the one or more drive rods may be configured to engage a fixed lead screw with a triangular nut, and wherein the drive rod may be further configured to engage at least two pistons of a fluid cartridge. The housing may include a controller configured to be operatively connected to the power supply, the controller may be configured to generate a pressure within the fluid cartridge by adjusting, via the motor, the drive rod and piston in a first direction relative to the fluid cartridge to dispense fluid in the fluid cartridge.

Abstract: A sealant tube for use in a pneumatic sealant gun for reducing or eliminating air bubbles in the sealant being dispensed. The sealant tube may fit within a hollow sleeve of the pneumatic sealant gun and contains sealant and a slidable plunger. The tube body may include an inner surface, an outer surface opposite the inner surface, a first opening, a second opening opposite the first opening, and pressure release openings formed through the tube body, such that air from a pressurized air source flows into the tube body and between the tube body and the hollow sleeve during use of the pneumatic sealant gun, equalizing pressure on the inner surface and the outer surface of the tube body. A seal or gasket may also be located proximate the second opening of the tube body, for forming an airtight seal between the hollow sleeve and the tube body.

Abstract: A method to prepare a self-decontaminating surface, where that method includes disposing a first coating on a surface, where that first coating comprises an organosilane, and disposing a second coating over the first coating, where the second coating comprises TiO2.

Abstract: A method for producing a plurality of measurement regions on a chip, and a chip having a plurality of measurement regions which is obtainable by the method.

Abstract: A granulated body manufacturing apparatus includes: a housing that includes a cylindrical internal space, is disposed so that a center axis direction of the internal space is horizontal, and houses a raw material for a granulated body inside the internal space; an agitation blade that is provided along an inner circumferential surface of the internal space, and upon being rotated around the center axis, scoops up the raw material accumulated in a bottom portion of the internal space and makes the raw material fall down from an upper position inside the internal space; and a crossing blade including a wire having a wire diameter not exceeding 0.3 mm, the wire being provided at a position in a range, inside the internal space, in which the crossing blade does not come into contact with the agitation blade, and being looped around a framework body that rotates around the center axis.

Abstract: A pattern imprint template incudes a patterned recesses and a layer formed over the patterned recesses. The pattern recesses form a pattern in a resist when brought in contact with a substrate with a resist thereon. The layer formed over the patterned recesses has a first surface energy. The first surface energy is lower in comparison to a second surface energy of the substrate with the resist thereon. The lower first surface energy in comparison to the second surface energy of the substrate avoids trapping gas in the resist by pushing gas toward the imprint template for venting through the patterned recesses.

Abstract: One aspect of the invention provides a method for fabrication of a membrane on a surface. The method includes: providing a surface interfacing two environments, wherein one of the environments is a liquid; providing a flow-recirculating fluidic device having channel exits in the liquid environment in proximity of the surface; and delivering locally one or more processing solutions. The one or more processing sources including one or more membrane sources adapted and configured to form a membrane on the surface.

Abstract: A method for the production of a polychromatic and/or spatially polychromatic or a monochrome colored ceramic body, in particular a dentine ceramic blank, which is dyed in this way, wherein in order to control a targeted distribution of color pigments (101, 102) within a porous ceramic (100), in a first step, which is a loading step (3c), the ceramic (100) is loaded with a color pigment solution (104). In a second step, which is a distribution control step (4d), the distribution of the color pigments (101, 102) within the ceramic (100) is controlled by controlling one or more environmental parameters (106) in an environment (108) and/or the pressure and/or temperature.

Abstract: Electrical biasing of ultrasonic transducers of an ultrasound device is described. The ultrasonic transducers may be capacitive micromachined ultrasonic transducers (CMUTs). The ultrasonic transducers may be grouped together, with the different groups receiving different bias voltages. The bias voltages for the various groups of ultrasonic transducers may be selected to account for differences between the groups.

Abstract: An ultrasound sensor includes: a diaphragm; a plurality of first electrodes; a plurality of second electrodes; and a plurality of piezoelectric layers which is provided between the first electrode and the second electrode, in which, in a Z-direction, a portion in which the first electrode, the piezoelectric layer and the second electrode are overlapped is referred to as an active portion, and a range to the extent that the diaphragm is oscillatable by driving the active portion is referred to as a movable portion, when a unit including one movable portion and the active portion which is provided within the one movable portion is referred to as one ultrasound element in plan view, two or more types of ultrasound elements in which a dimension of the active portion with respect to a dimension of the movable portion is different from each other in plan view are provided.

Abstract: A method of processing objects is disclosed using a programmable motion device. The method includes the steps of acquiring an object from a plurality of mixed objects at an input area, perceiving identifying indicia in connection with the object, assigning an intermediate station to a destination location for the object responsive to the identifying indicia in connection with the object, and moving the acquired object toward the intermediate station.

Abstract: An automated shuttle sorter is disclosed that includes a carriage that is movable from a load position at which the carriage may be loaded, and at least two destination locations into which any contents of the carriage may be provided from the carriage

Abstract: A lumber sorter includes a plurality of bins. A conveyor carries lumber (e.g. boards) along a path extending above the plurality of bins. A diverter is selectively operable to allow the conveyor to carry the boards past one or more bins or to divert a selected board into a selected bin. The diverter may comprise an upstream gate and a downstream gate, each operable to move between respective closed positions and open positions. In the closed positions, the top surfaces of the upstream and downstream gates are substantially level and allow boards to travel along the path as directed by the conveyor. The diverter may be actuated to the open position in which the upstream and downstream gates are separated, thereby providing a path for a board to fall into a bin.

Abstract: Embodiments described herein generally relate to a particle collection apparatus and probe head for the collection of particles on process tool components. In one embodiment, a particle collection apparatus for counting particles present on a processing tool component is disclosed herein. The particle collection apparatus includes a particle collector. The particle collector is configured to scan a processing tool component and collect particles collected from the processing tool component. The particle collector includes a body and a probe head coupled to the body. The probe head has a probe body and a controlled spacing element. The controlled spacing element is coupled to the probe body and is configured to form a uniform manifold between the probe body and the processing tool component.

Abstract: An apparatus for cleaning chandeliers includes a hand-held fluid source having a proximal end connected to a source of hot water under positive pressure and a distal end having a spray head for discharging hot water under pressure in a spray pattern. A vacuum shield has at least one vacuum inlet connected to a source of negative pressure. Hot water discharged from the spray head is attracted to the vacuum shield when the spray head and the vacuum shield are disposed in relatively close proximity to one another and the vacuum shield is in fluid communication with the source of negative pressure. An object disposed between the spray head and the vacuum shield is cleansed by the action of hot water under positive pressure impinging against it. The vacuum shield protects objects not disposed between the spray head and the vacuum shield.

Abstract: A surface microstructure comprises a surface (2); and a plurality of protrusions (4) on the surface, wherein each of the protrusions has a base portion which extends away from the plane of the surface and an extending portion which extends in a direction which has a component parallel to the plane of the surface, and wherein the protrusions each have a length between 0.25 and 100 ?m and a width between 0.1 and 1.5 ?m.