Abstract: A filter delivery device for implanting a vessel filter within a blood vessel of a patient's body. The filter delivery device includes a mechanism for preventing hooks and/or legs on a vessel filter from entangling with each other while the vessel filter is loaded within the delivery device. In one variation, the filter delivery device includes a delivery catheter with grooves at the distal end lumen opening. When a vessel filter with radially expanding legs is compressed and inserted into the distal end of the delivery catheter, the hooks on the distal end of the legs are received and separated by the corresponding grooves on the delivery catheter. In another variation, a pusher rod, with a receptacle for receiving the hooks, is positioned within a delivery catheter to prevent the entanglement of the hooks and/or legs of a filter loaded within the delivery catheter.

Abstract: An embolic protection device includes an expandable and contractible filter that can be supported by one or more struts. The struts can be connected to the filter or interwoven into the filter, so as to assist in the expansion and contraction of the filter. In one embodiment, the proximal ends of the struts connect to a joint that is fixed in position relative to a delivery wire, while the distal end of the filter connect to a joint that slides relative to the delivery wire.

Abstract: A lung device for restoring lung elasticity includes fixation members and a connecting member. The fixation member includes a first radially expandable fixation member and a second radially expandable fixation member. The first radially expandable fixation member defines a first profile in an expanded state and a lumen. The second radially expandable fixation member defines a second profile in an expanded state and a lumen. The connecting member extends between and connects the first and second fixation members. The lung elasticity restoring device is capable of reversibly extendable between an inspiration configuration and an expiration configuration, may be extendable to the inspiration configuration, and biased to the expiration configuration by the connecting member.

Abstract: A method for treating a lung may include forming a channel between a first airway and a second airway through a tissue of the lung to allow air trapped within the first airway to flow through the channel and the second airway, and inserting a support member into the channel.

Abstract: A stent graft 30 has a bare end stent 31 which partially overlaps the next stent 32 with the end 36 of the graft material 34 being shaped to follow the distal peaks 35 of the end stent and the proximal peaks 47 of the next stent. The proximal peaks 37 of the end stent have a greater radius of curvature than the distal peaks 35 of the end stent.

Abstract: Methods and devices are provided for anchoring a ligament or tendon to bone. In general, various inserter tools are provided for simultaneously delivering an expandable sheath and an expander into bone. With both components of the implant mounted on the same tool, the sheath and a ligament can be advanced into a bone hole and the expander, which trails behind the sheath during delivery of the sheath, can be advanced into the sheath to expand the sheath and anchor the sheath and ligament within the bone hole.

Abstract: Provided is technology which can prevent plunger deformation and further stabilize an intraocular lens insertion operation, even when an insertion tube section of an intraocular lens insertion apparatus has been further reduced in terms of the diameter thereof and has been made flatter. The intraocular lens insertion apparatus includes: a tip end region where a plunger comes into contact with an intraocular lens main body and an intraocular lens holding section; and a bar-shaped section extending from the rear end of this tip end region to the rear of the plunger. The bar-shaped section has a fixed thickness in the direction of the optical axis of the intraocular lens, and has an increasing thickness in a portion where the distance from the tip end of the tip end region is equal to or greater than a predetermined distance in a direction perpendicular to the optical axis direction and perpendicular to the plunger advancement direction.

Abstract: Intraocular lens delivery devices and methods of use.

Abstract: A prosthetic heart valve includes an annularly collapsible and re-expandable supporting structure extending between an inflow end and an outflow end and including a plurality of struts, a plurality of leaflets disposed inside the supporting structure and operative to allow flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end, a sheet circumferentially disposed on an inner surface of the supporting structure and coupled to the supporting structure, a reinforcing core coupled to at least one of the plurality of leaflets, and a plurality of stitches coupling the reinforcing core to the sheet and one of the plurality of leaflets.

Abstract: Embodiments hereof relate to a transcatheter valve prosthesis including a tubular fabric body, a first or inflow tubular scaffold attached to a first end portion of the tubular fabric body, and a second or outflow tubular scaffold attached to a second end portion of the tubular fabric body. A prosthetic valve component is disposed within and secured to an intermediate portion of the tubular fabric body that longitudinally extends between the first and second end portions of the tubular fabric body. The intermediate portion is unsupported such that neither of the first and second tubular scaffolds surrounds the intermediate portion of the tubular fabric body. The intermediate portion may include one or more windows for coronary access and may include one or more commissure reinforcement members coupled thereto to provide support for the prosthetic valve component.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end. A plurality of eyelets is arranged in rows and columns on the body for distributing load from the plurality of leaflets.

Abstract: An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted. The holders may have solid legs that directly contact and constrict and hold the commissure posts without the use of sutures in tension that might creep over the time in storage. The holder may have a base in contact with the inflow end and a shaft portion that projects through the valve leaflets and cooperates with movable legs on the outflow end of the valve in contact with the commissure posts. The holders may, alternatively, have flexible leg members that extend through the valve and have distal end portions configured to extend over and shield the tips of commissure posts.

Abstract: A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations.

Abstract: In one example, we describe an apparatus for heart surgery that enables the surgeon do the attachment for torn tissue or connector for the bottom end, located inside the heart, from left atrium, with ease. Thus, it reduces the problem drastically, with lower risk and lower failure rate. Different variations are shown here, with various examples. This is a very valuable tool for the heart surgeons. The light and camera are optional features for the surgeon's installer tool.

Abstract: Apparatus is provided that includes a tissue anchor, which (a) includes a helical tissue-coupling element which has a distal tissue-penetrating tip at a distal end of the tissue anchor, and is configured to be advanced into soft tissue, and (b) is shaped so as to define a longitudinal channel extending to the distal end of the tissue anchor. The apparatus further includes (a) a depth-finding tool, which includes a radiopaque bead, which is shaped so as to define a hole therethrough, and which is positioned within and axially moveable along the channel so as to serve as a marker indicating a depth of penetration of the tissue-coupling element into the soft tissue, and (b) and a shaft that is removably positioned within the channel, such that the shaft passes through the hole of the bead, and such that the bead is axially moveable along the shaft and along the channel.

Abstract: The present invention relates to a tasseled cortical bone graft and a method of preparing cortical bone in thin strips or tubes then fully demineralizing it to give it formed flexibility and then creating a plurality of strands extending from one or more connection locations in the cortical bone in a fashion similar to a tassel.

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

Abstract: Methods, systems, and devices for replacement of a joint with a prosthetic system that replicates the natural kinematics of the joint is disclosed. A prosthetic system according to one embodiment includes a tibial component having a tibial plateau and a tibial stem portion, the tibial plateau having a top side and a bottom side, a tibial insert, with a bearing surface, adapted to be positioned on the top side of the tibial plateau, a femoral component having a base portion and a central housing, the femoral component having an axis of extension-flexion rotation, the base portion having a pair of condyles, an a mechanical linkage component linking the tibial component with the femoral component and with the tibial insert in between the tibial component and the femoral component, so that there is a center of contact between the condyles and the bearing surface.

Abstract: Systems, devices, and methods are described for providing orthopedic knee inserts. The orthopedic knee inserts include a surface portion having a lip configured to couple with a mating member of a tibial component, where the lip has recesses that define non-continuous contact regions between the lip and the mating member of the tibial component. Alternatively, or additionally, in certain embodiments the mating member includes a shelf for mating with an insert, the mating member having a plurality of splines disposed along the shelf that form non-continuous contact regions between the mating member and the insert.

Abstract: Devices and methods for protecting the neurovascular structures about the vertebral column are provided. One embodiment of the invention comprises a neuroprotective stent or device adapted for placement in an intervertebral foramen of a vertebral column and configured to resist compression or impingement from surrounding structures or forces. The stent or device may further comprise a flange or hinge region to facilitate attachment of the device to the vertebrae or to facilitate insertion of the device in the foramen, respectively.

Abstract: A vertebral implant (1) is provided to be implanted in a patient's intersomatic space. The implant (1) includes an intersomatic cage (2) and at least one fixing screw (10) that is intended to be screwed into a bony mass through a well (7) of the cage (2) to stabilize the position of the cage (2) within the intersomatic space. In addition, the well (7) and the screw (10) form a system for the self-locking of the screw (10) in the well (7) in which the screw (10) is locked into position by the well (7).

Abstract: Systems and tools for inserting and securing an implant within the intervertebral space. An intervertebral disc implant with upper and lower bearing members with an articulation interface between the members for providing relative motion therebetween. The implant may be provided with various securing members for fixing the implant within the intervertebral space. A tool may be used to insert the implant, which includes a plurality of shiftable implant engaging members that are shiftable between non-engaging and engaging configurations to alternatively release or hold the implant.

Abstract: Embodiments of the invention is directed to methods of forming a bone-like material, by placing a matrix into a culture container, adding cells to the matrix, placing the tissue-cell construct into the culturing environment and incubating the construct under appropriate conditions for the time required to produce an amount of bone-like material of sufficient volume to be harvested for further processing. Other embodiments of the invention are directed to the use of the bone-like material formed by methods of the invention in implantation procedures.

Abstract: A composite interbody device for use with spinal fusion surgery is described herein. The composite interbody device comprises a central body made from a radiolucent biocompatible polymer (e.g., PEEK or UHMWPE) and metallic plates, which are placed at the superior and inferior surfaces of the central body. The metallic plates are comprised of an end plate that is adjacent to a vertebral body and an intermediate plate that is adjacent to the central body. The end plates may have one or more arrays of apertures to facilitate bone growth into the end plates to secure the interbody device within the intervertebral space. The intermediate plates may also have one or more arrays of apertures to allow the central body to bond to the end plates through compression molding, injection molding, and/or heat molding.

Abstract: An intervertebral spinal spacer that can include a substantially annular body that can include an upper surface, a lower surface, an outer surface, and an inner surface. The inner surface of the substantially annular body can define an internal cavity. The annular body can include a plurality of outer apertures and a plurality of inner apertures connected by a plurality of fluid passages that can draw fluid into the internal cavity.

Abstract: The present invention relates generally to medical devices and methods for use in spinal surgery. In particular, the disclosed system relates to an intervertebral spinal implant assembly sized and dimensioned for the lumbar or cervical spine implantable via an anterior approach. The device includes an implant, bone fasteners, and instruments for delivering the implant and bone screws.

Abstract: A horizontal and vertical expandable tissue spacer implants, insertion tools, assembly methods and surgical methods are disclosed. The horizontal expandable tissue spacer implant includes a first lateral member with a first side, a second lateral member with a first side, and an intermediate spacer member. The intermediate spacer member is adapted to cooperatively engage and hold the first side of the first lateral member and the first side of the second lateral member. A vertical expandable tissue spacer implant includes a top member with a bottom surface, a bottom member with a top surface, and an intermediate spacer member with a coupling mechanism. The coupling mechanism cooperatively engages the bottom surface of the top member to the intermediate spacer member and the top surface of the bottom member to the intermediate spacer member.

Abstract: Provided is a preoperatively designed guidance tool for intraoperative use during acetabular cup replacement surgery, comprising: a patient-specific template having at least one surface that registers with a selected surface of the patient's acetabulum; and a guide portion that provides an orientation or a position and orientation of an acetabular cup according to a preoperatively planned orientation or position and orientation. The guidance tool may further comprise a verification tool that cooperates with the guide portion and includes at least one mating surface that registers with a selected surface of the patient's anatomy, wherein correct positioning of the verification tool on the patient's anatomy confirms correct orientation of the patient-specific template in the patient's acetabulum.

Abstract: An alignment guide is described that includes a shaft having a longitudinal axis and a housing attachable to the shaft and rotatable about a first axis that is substantially perpendicular to the longitudinal axis. A guide arm the extends from the housing at a predetermined angle along a second axis. A spirit level is connected to the housing on a plane aligned with the predetermined angle.

Abstract: A stemless humeral component for replacing the humeral head of a patient's humerus includes a support flange having a number of cantilevered legs extending distally away from a bottom surface thereof. Instruments and methods for surgically installing the stemless humeral component are also disclosed.

Abstract: A method of sizing and balancing a knee including: placing an integrated orthopedic instrument in contact with a resected distal femoral surface of a femur of a knee in flexion such that medial and lateral posterior feet of a tensor frame of the instrument are in contact with posterior condyles of the femur and such that medial and lateral posterior feet of a sizer body of the instrument are positioned on a spacer placed on a resected proximal surface of the patient's tibia; securing first and second wings extending from a central portion of the tensor frame on the resected distal femoral surface; rotating the sizer body relative to the tensor frame via a rotation mechanism that connects the sizer body and the tensor frame to balance the ligaments; and sizing the patient's femur by moving a stylus coupled to the sizer body on an anterior surface of the femur.

Abstract: An optical trial implant device that can be used to determine an appropriate size for an intervertebral disc implant can be configured so that one or more portions of the device can be optically transparent or radiolucent. The device can include an imaging device that can be used to view and image the intervertebral space through the optically transparent portion(s) of the device. The device can be used to determine the extent and quality of preparation of an intervertebral space between adjacent vertebral bodies for a surgical procedure, such as a disc replacement or spinal fusion procedure. The acquired image information can be transmitted to a mobile computing device for display in real time and/or stored for future use. The information may also be used to determine parameters indicating the quality of endplate surface preparation.

Abstract: In some embodiments of a prosthetic or orthotic ankle/foot, a prediction is made of what the walking speed will be during an upcoming step by using one sensor from which the walking speed can be predicted, and a second sensor from which ankle torque can be determined. A controller receives inputs from those sensors, and controls a motor's torque so that the torque for slow walking speeds is lower than the torque for fast walking speeds. This reduces the work performed by the actuator over a gait cycle and the peak actuator power delivered during the gait cycle. In some embodiments, a series elastic element is connected in series with a motor that can drive the ankle, and at least one sensor is provided with an output from which a deflection of the series elastic element can be determined.

Abstract: A quick release prosthetic connector for detachably joining a threaded prosthetic socket to a prosthetic includes a socket-connect portion configured for connection to the prosthetic socket. A plurality of locking members is carried by the socket-connect portion. The plurality of locking members are positional between a release position and a locking position and normally biased in the locking position. A prosthetic-connect portion is configured for connection to the prosthetic. A plurality of locking member engaging apertures is provided in the prosthetic-connect portion. The plurality of locking member engaging apertures are configured to selectively receive the plurality of locking members, respectively, of the socket-connect portion in the locking position of the plurality of locking members. A lock portion is carried by the socket-connect portion. The lock portion is configured to selectively lock and release the prosthetic-connect portion with respect to the socket-connect portion.

Abstract: Radiopaque markers for use with stents implantable within a body vessel are provided with one or more through-holes. Each through-hole extends through the thickness of the marker to expose a portion of the stent underlying the marker. The marker is welded to the stent through each through-hole. Also provided are stents incorporating a radiopaque marker having one or more through-holes suitable for receiving a plug weld. Methods are provided for securing a radiopaque marker having one or more through-holes to a stent via welds.

Abstract: A short sheath delivery system comprises a delivery device for a stent and a fixing device. A delivery device is used for delivering a stent part on a stricture lesion via an endoscope along a guidewire; the fixing device is used for fixing the delivery device on an endoscope biopsy port. The delivery device comprises a tip, an inner rod, a secondary rod, a main rod, a sliding rod, a trailing end, a guidewire cavity, an injection tube, a stent, a short sheath, a connection thread and a handle; the stent is preloaded in an empty cavity formed by the inner rod and the short sheath; the length of the short sheath is longer than that of the stent, and is less than that of the secondary rod; the external diameter of the secondary rod is less than the inner diameter of the short sheath, and the external diameter of the main rod is equal to or greater than that of the short sheath; the handle is sleeved around the sliding rod; and the handle is connected with the short sheath by the connection thread.

Abstract: A protective patella guard adapted for use with a knee brace having upper and lower frame members. The protective patella guard including an upper cup element coupled to the upper frame member, a lower cup element coupled to the lower frame member, and an intermediate cup element operatively coupled to the upper cup element and lower cup element. The patella guard is transitional between a first configuration and a second configuration, wherein a degree of overlap between the upper cup element, the lower cup element, and the intermediate cup element decreases as the patella guard transitions from the first configuration to the second configuration.

Abstract: A dynamic infant head support for preventing, or correcting, the abnormal shape of a head of an infant, and a method of using the support for treating deformational plagiocephaly. The support is an oval-shaped pillow, with a central opening to receive the head of the infant to be treated. Spaced barriers divide the interior of the pillow into a plurality of compartments. A ring-like manifold passes through the pillow and communicates with each compartment. A plurality of valves is operatively associated with the manifold; one valve is located in each compartment. The valves allow fluid, such as pressurized air, in the manifold, to inflate individual compartments. The manifold is pressurized by a pump, at a remote location. A remote controller is connected to the valves by electrical leads for governing the sequence of operation of the valves, and regulating the duration of time that each valve is open.

Abstract: A urine collection bag (1) comprising an anti-reflux valve in the form of a foil valve (8), located at the inlet (5) of the bag. The valve secures a liquid tight seal of the bag when filled and that no reflux occurs during catheterization. The bag comprises a tube member (11) that can be brought in a position so as to bypass the foil valve and the bag can be emptied in an easy and non-messy way.

Abstract: An intrauterine device includes a central support member, first and second internal flexures and first and second external flexures. The first and second internal flexures each include a first section having a first stiffness, a second section having a second stiffness, and third section having a third stiffness, wherein the second stiffness is more flexible than the first and third stiffness and wherein the first section of each internal flexure is coupled to the central support member. The first and second external flexures are coupled to the central support member and coupled to the third sections of the first and second internal flexures, the first and second external flexures in combination with the first and second internal flexures being configured to extend from a collapsed position parallel to the central support member to a deployed position flexing away from the central support member.

Abstract: Structures and protocols are presented for supporting a medical or veterinary patient with therapeutically significant normothermia and other practical advantages.

Abstract: Methods and apparatus for producing saline slush for surgical applications. Producing surgical saline slush in a slush bottle that is a rigid or semi-rigid, high integrity, sturdy container that resists punctures and leaks to better maintain a sterile barrier and does not rely on having an external object placed in the fluid to mix the slush. Slush is agitated within the slush bottle. Slush bottle features are discussed which agitate and condition slush for use in medical procedures. The slush bottle may be rotated using a pair of rollers. A slush station may have one or more compartments for the production of slush and a basin shell for maintaining slush as slush in a basin. Specialized techniques for a vertical slush bottle are discussed.

Abstract: A device for use during an intravitreal injection procedure, the device including: a main body portion with a handle at one end for holding the device; and, a contact portion at the other end for contacting the surface of an eye; wherein the contact portion includes a distance indicator for indicating a pre-determined distance from a reference point on the eye.

Abstract: Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball.

Abstract: A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. The apparatus can also include additional pressure regulation control systems. The gas mixture apparatus can be used to introduce and automatically perform the steps to achieve a desired concentration of the one or more gases contained in the pressurized chamber. The gas mixture apparatus can include the pressurized chamber within the apparatus itself such that no external devices are necessary for introducing the one or more gases into the mixing chamber.

Abstract: Ocular surgery may be performed by a variety of systems, processes, and techniques. In certain implementations, systems and processes for ocular surgery may include the ability to emulsify a lens in an eye using a modular hand-held system including a phacoemulsification unit detachably coupled to a pump unit and remove lens portions from the eye using suction provided by the pump unit. The system and the process may also include the ability to decouple the phacoemulsification unit from the pump unit, couple an irrigation-aspiration unit to the pump unit to form a second hand-held system, and remove material from the eye using suction provided by the pump unit.

Abstract: In certain embodiments, a handpiece system includes an ultrasonic handpiece and a spatula. The ultrasonic handpiece includes a vibration source and a horn. The vibration source is configured to produce ultrasonic vibrations, and a horn is configured to transform the vibrations into ultrasonic motion. The spatula is coupled to the horn and configured to move according to the ultrasonic motion. The spatula may have any suitable shape and size.

Abstract: A vitrectomy probe includes a hand-graspable body and an outer tube extending from the hand-graspable body. The outer tube includes a closed distal end and a first port sized to receive tissue. The vitrectomy probe also includes an inner tube within the outer tube with a second port that is selectively alignable with a portion of the first port to allow fluid flow and uniquely sized to increase fluid flow. The inner tube includes a distal tip with a cutting edge on each of the distal and proximal sides of the tip. The distal tip has a smaller diameter than that of the inner tube at a proximal side of the second port. The proximal side of the second port includes a guiding surface that slidably bears on an inner surface of the outer tube to prevent the distal tip from excessively protruding from the first port of the outer tube.

Abstract: An ocular implant delivery system is provided with a number of features. In some embodiments, the delivery system comprises a rotation mechanism configured to rotate and orient a cannula of the system, and an advancement mechanism configured to advance and retract an ocular implant through the delivery system and into an eye of a patient. In some embodiments, the cannula is sized and configured to be inserted into Schlemm's canal of the eye. The ocular implant is configured to maintain its orientation within the delivery system as the cannula is rotated. In some embodiments, the ocular implant automatically disengages the delivery system when it is advanced beyond a distal tip of the delivery system. Methods of implanting an ocular implant are also provided.

Abstract: An intraocular pressure compensating and regulating valve installed inside the eye's cornea includes: a valve body having a valve seat at an end; a mobile element connected to the valve seat under normal intraocular pressure conditions inside the eye, the mobile element being configured such that it can be separated from the valve seat when the intraocular pressure exceeds the intraocular pressure limit; and an element to keep the mobile element in contact with the valve seat.