Abstract: An intraocular shunt can be placed into a human eye using a hollow shaft having a distal tip with a bevel. The hollow shaft can be advanced through the anterior chamber while the hollow shaft holds the intraocular shunt. The sclera can be penetrated with the beveled distal tip until all of the bevel is positioned distal to a distal wall of the sclera. The shunt can be advanced at least partially from the hollow shaft into a drainage space of lower pressure than the anterior chamber. The hollow shaft can be withdrawn from the eye, leaving the shunt extending from the anterior chamber completely through the sclera to the drainage space.

Abstract: An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.

Abstract: A steerable laser probe may include a handle, an actuation structure of the handle, a housing tube, a flexible tube, an optic fiber, and a wire having a pre-formed curve. The flexible tube may be disposed within the housing tube wherein a distal end of the flexible tube projects out from a distal end of the housing tube. The optic fiber may be disposed within an inner bore of the handle, the housing tube, and the flexible tube. The wire may be disposed within the housing tube.

Abstract: Dressings, systems, and methods are disclosed, in some embodiments, that involve treating a tissue site with reduced pressure. In one embodiment, a reduced-pressure dressing may include a dressing bolster, a retention pouch, and a sealing member. The dressing bolster may be adapted to apply a compressive force to the tissue site capable of closing a wound or incision therein. The retention pouch may be adapted to retain and manage fluid extracted from the tissue site to keep the tissue site substantially free of fluid and to prevent clogging of the reduced-pressure dressing. The sealing member may provide a seal over the retention pouch, the dressing bolster, and a portion of the epidermis of the patient. Other dressings, systems, and methods are disclosed.

Abstract: Devices and methods for wound treatment are disclosed. A chamber may define a treatment space having an interior engineered surface including a plurality of structures configured to provide pathways for the distribution of negative pressure and to exert mechanical stress on a wound. In some specific embodiments, the devices and methods may treat wounds on the head, neck, and face. One or more tubes may be in fluid communication with the treatment space to facilitate the application of negative pressure, the introduction of therapeutic agents, and the removal of wound material.

Abstract: A method and device for turning a continuous supply of absorbent cores oriented in cross machine direction into a machine direction orientation and dividing the supply of absorbent cores into two or more sub-lines is provided. The device includes a plurality of turning plates which each include means for picking up, holding and releasing the absorbent cores, means for reversibly transferring the turning plates from a core pick-up point to a core release point, each turning plate being mounted rotationally on an axis, so that the absorbent cores can be re-oriented from a cross-machine direction at the pick-up point into machine direction at the release point while being held on the turning plates. Each turning plate includes means for picking up, holding and releasing two or more absorbent cores.

Abstract: An absorbent core structure for disposable absorbent articles, having improved fluid handling properties.

Abstract: An absorbent core assembly for use in a product for absorbing a liquid is disclosed. The core assembly has a first section and a second section. The first section is a quilted porous material that contains a slow acting but high absorption capacity SAP therein. The, second section is a quilted porous material that contains a fast acting but lower absorption capacity SAP therein. The first and second sections are in fluid communication with each other, whereupon a liquid which is exposed to the core assembly flows through the first section to the fast acting SAP in the second section to be absorbed quickly and rapidly by the fast acting SAP therein, while the slow acting SAP desorbs or takes liquid away from the fast acting SAP as well as absorbing the liquid itself to thereby trap the liquid in the core assembly.

Abstract: An object of the invention is to obtain spunbonded nonwoven fabrics including thin hollow fibers which have excellent lightweight properties and uniformity as well as exhibit high strength and flexibility. An aspect of the invention is directed to a spunbonded nonwoven fabric including hollow fibers of a propylene polymer, the hollow fibers satisfying the following requirements (a) to (c): (a) the C-axis orientation is at least 0.85, (b) the average fiber diameter is 5 to 20 ?m, and (c) the hollowness is 5 to 30%.

Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article. This signal includes a colored portion having a first shade and a second shade.

Abstract: There are provided a rear wheel rotatably provided in a body, a seat disposed on a top surface side of the body, a seat link mechanism by which the seat is supported to be movable up and down between a raised position and a lowered position on the top surface side of the body, and a brake mechanism which inhibits the rear wheel from rotating in interlock with the seat link mechanism, when the seat is raised from the lowered position to the raised position.

Abstract: A person support apparatus comprises a lower frame, a support, and an upper frame. The support is coupled to the lower frame. The upper frame has a head section and a foot section and defines a longitudinal axis passing through the head section and the foot section and a lateral axis substantially perpendicular to the longitudinal axis. The upper frame includes a tilt mechanism pivotably coupling the upper frame to the support. The tilt mechanism includes a base and a rocker nested within the base. The base and the rocker are pivotable with respect to one another about a pivot axis that passes through the base and the rocker and is substantially parallel the longitudinal axis. The upper frame is pivotable about the pivot axis with respect to the lower frame.

Abstract: An elevation structure system possesses anti-decubitus ulcer characteristics, and may cooperate with a mattress overlay also having anti-decubitus ulcer capabilities as part of a mattress overlay system, in which multiple elongate, positionally adjustable, relatively moveable risers are configured for selective placement in conditions of transverse, subposed, under-engagement with the sides of an overlay to create substantially non-inclined, elevated, depth-supplemented regions at locations along the length of the overlay. The elevation structure and overlay may each include a dynamic-response core expanse formed of an open-cell, compressible viscoelastic foam coated with an elastomeric, moisture- and gas-flow-managing, differential-thickness coating structure load-transmissively bonded to the entirety of the outside of said core expanse to function as a dynamically-responsive unit therewith.

Abstract: A device for assisting a caregiver in delivering therapy to a patient, the device comprising a user interface configured to deliver prompts to a caregiver to assist the caregiver in delivering therapy to a patient; at least one sensor configured to detect the caregiver's progress in delivering the therapy, wherein the sensor is other than an electrode in an electrical contact with the body; a memory in which a plurality of different prompts are stored; a processor configured to determine which of the different prompts should be selected for delivery based on the progress detected by the sensor.

Abstract: A lower leg elevation and support device for elevating and supporting a lower leg includes a lift and a plurality of wedges. The lift and each wedge having a thick end, a thin end, a bottom, a top, and a pair of opposing sides. The tops, the bottoms and the thick ends are substantially rectangular. The opposing sides are triangular, such that the lift and the wedges are cuneal. A slot extends from the thick end of the lift to proximate to the thin end of the lift, defining an upper section and a lower section of the lift. Each wedge is insertable into the slot, elevating the upper section of the lift relative to the lower section of the lift. A plurality of fasteners is configured to secure the lift to a leg of a user.

Abstract: A patient transport device includes an inflatable torso support and one or more straps coupled to sides of the inflatable torso support. Each strap can be configured at least as a single loop. A strap concealment device can be coupled to the inflatable torso support to span a major face of the inflatable torso support. The strap concealment device can include a central panel spanning the major face and one or more side panels extending from a perimeter of the central panel. The one or more side panels can terminate at an edge distally disposed from the central panel at a bunch-gathering binding. The one or more side panels can be selectively foldable between a first position concealing the inflatable torso support and some or all of the one or more straps and a second position exposing the inflatable torso support and the one or more straps.

Abstract: A patient positioning system for use with a patient on a bed includes a sheet having a bottom surface configured to be placed above the supporting surface of the bed and a top surface opposite the bottom surface, and a wedge having a base wall, a ramp surface, and a back wall, with the ramp surface joined to the base wall to form an apex. The wedge is positioned under the sheet such that the base wall confronts the supporting surface of the bed and the ramp surface confronts the bottom surface of the sheet. The bottom surface of the sheet and the ramp surface of the wedge have engagement members forming a selective gliding assembly that resists movement of the sheet with respect to the wedge in at least one direction and permits movement of the sheet with respect to the wedge in at least one other direction.

Abstract: A patient transfer sled has a support structure including at least one air cushion adjacent a major surface thereof. The air cushion includes a flexible material at least partially surrounding a rigid material, and a portion of the flexible material has a plurality of holes extending therethrough. Systems for patient transfer may include a support surface, such as a table, a patient transfer sled having at least one air cushion, and a source of pressurized air. Methods for moving a patient relative to a support surface include positioning a patient on a patient transfer sled having at least one air cushion, and inflating the air cushion with air to form a sheet of flowing air between the patient transfer sled and the support surface. The methods may be used, for example, to move a patient on an air film over a surface within a system.

Abstract: Disclosed is a patient lift system having a sling bar with an inductively charged integrated scale. The lift system comprises a lift apparatus, a lift strap connected at a first end to the lift apparatus, a sling bar connected to a second free hanging end of the lift strap, the sling bar having a scale with a tension load cell integrally disposed therein for measuring forces applied thereto and a power source electrically connected to the scale to provide power to the scale and load cell. An accelerometer is disposed within the sling bar to determine a tilt angle of a lift axis of the load cell relative to a vertical direction of gravitational force. Programming stored in a processor of the integrated scale calculates an accurate weight of an active load suspended from the sling bar, based on the determined tilt angle and the measured force on the load cell.

Abstract: The present inventive subject matter describes a device and system for positioning, adjusting, and stretching a patient's extremity for surgical procedures where alignment is critical and minute adjustments may be required repeatedly. The device helps in maintaining the patient's extremity stationary, once the physician has selected the precise position for the elected procedure. The device uses using a combination of an articulating and a rotating frame, support plates and support rings that are attached to the extremity surgical positioning system. The system acts as a limb splint that is firmly attached to the surgical table. The support plates are attached to the patient via a series of adjustable straps preventing the extremity from moving independently of the support plate. A locking rack and gear configuration has adjustable locking pivot points that are positioned along and within the outer/inner proximal tube and outer/inner distal tube that lengthens or rotates various portions of the extremity.

Abstract: A body bag includes a first layer having an upper surface and a lower surface, and a second layer coupled to the first layer. The upper surface of the first layer at least partially defines a first cavity sized to receive the body. The second layer has an upper surface and a lower surface. The lower surface of the first layer and the upper surface of the second layer at least partially define a second cavity sized to receive a stiffening mechanism.

Abstract: A first call pouch includes an inner layer forming a compartment comprising at least one sidewall, a bottom wall and a top having a zippered opening. The inner layer is water resistant, proof, or sealed to contain fluids. The inner layer further including one or more pockets formed therein for storage of related items including gloves. The zippered opening is a bi-directional zipper extending substantially the entire length of the bag. An outer layer encapsulates the inner layer. The outer layer includes at least one outer sidewall, an outer bottom wall, and an outer top wall that shares the zippered opening with the inner layer whereby opening of the bi-directional zipper provides access to the inner compartment. Further, the outer bottom has a pocket adapted to receive a pad, and the outer layer top wall has at least one pocket.

Abstract: A apparatus includes an a exoskeleton system with a plurality of sensors for generating signals indicating a current motion and a current arrangement of at least the exoskeleton system, a hip segment, and at least one lower limb. The lower limb includes thigh and shank segments for coupling to a lateral surface of a user's leg. The thigh segment includes a first powered joint coupling the thigh segment to the hip segment, a second powered joint coupling the thigh segment to the shank segment, and a controller coupled to the sensors, the first powered joint, and the second powered joint. The controller is configured for determining a current state of the exoskeleton system and a current intent of the user based on the signals and generating control signals for the first and second powered joints based on the current state and the current intent.

Abstract: Provided are methods of treating or improving neurological conditions and/or outcomes thereof in a subject afflicted with a neurological condition. The methods include placement of a device comprising at least two calibrated, differential disturbances or protuberances under the subject's foot.

Abstract: An oral appliance for administering a stimulus, such as a substance, to the mouth of a user includes a flexible tube having an inlet portion, a first curved portion forming an ear loop connected to the inlet portion, a second curved portion forming a lip bend connected to the first curved portion, and an outlet portion extending from the second curved portion. Alternatively, a mouthpiece for delivering a substance to the mouth of a user includes a housing having an inlet portion, a riser portion extending upwardly from the inlet portion and a curved outlet portion. A flexible tube is coupled to the housing. A method of delivering a substance to a predetermined location in a user's mouth includes disposing a flexible tube between a row of teeth and an interior surface of a cheek. The flexible tube has an exit port positioned in a rear portion of the user's mouth.

Abstract: A portable rolling massager is provided that includes a spindle, a roller rotatably mounted on the spindle, and a covering for the roller that features a comfortable surface when applied to the skin and pressure is applied to muscles underlying the skin. Heating and cooling of the cover provides other therapeutic benefits. Storage in the spindle accommodates weights, flashlights, key storage, music devices, and the like. Hand grips having distal ends are designed to provide the ability to massage trigger points that develop in the muscles.

Abstract: A hospital-grade basin holds water for washing patients, or alternatively converts easily/quickly for a patient's limb to rest comfortably within and across a portion of the basin. In a first embodiment, half-moon shaped openings on opposite sides of the basin side wall(s) comfortably support the limb at a reduced height with respect to adjacent side wall portions, which serve as a partial shield during wound irrigation, and aid fluid collection. The shaped openings may each be sealed with a hinged door in a closed position, using a friction fit, to form the traditional, watertight basin. In an alternate embodiment, the doors may be secured in the closed position using an elastomeric leaf-spring-shaped member. In other embodiments, rather than cutouts and doors, opposing portions of the side wall may instead be formed of an over-molded elastomeric material that conforms to the patient's limb, or may instead be formed like a bellows.

Abstract: It comprises a connecting member and an arm structure having at least one hose connector associated with at least one skin treatment machine applicator. Device is suitable for maintaining the applicators at a given position when in use. A skin treatment assembly is further provided comprising a suction machine for applying pressurized air to a patient through applicators connected to corresponding hoses and the support device.

Abstract: A method of making a pharmaceutical compounding system having automated micro-dosing capability, the method comprising identifying a technology that can facilitate controlled and automated dispensation of material, such that the dispensation does not necessitate augmentation of material by mass or volume to aid with measurement or manipulation in order to achieve a level of dispensing precision that can be medically acceptable for at least some drug substances; and adapting the technology for prescription-specific operability for producing customized drug products, the adapting comprising configuring the technology for production of pills in prescribed numbers with prescribed drugs at prescribed doses via distinct runs for respective patients.

Abstract: For a person who has a percutaneous endoscopic gastrostomy (“PEG”) tube and an esophagus stoma, an ostomy pouch is provided, where the pouch forms an inlet connected to the esophagus stoma and an outlet connected to one end of a interconnecting tube. An opposing end of the interconnecting tube is connected to the PEG tube, so that when the person consumes matter by mouth, the matter flows out the stoma, through the ostomy pouch, the interconnecting tube and the PEG rube, and into the stomach.

Abstract: The present invention relates to a cosmetic tissue comprising microemulsion particles, and to a production method for same and method of using same. The present invention provides a cosmetic tissue to which is securely attached a dried composition comprising microemulsion particles of no more than 5,000 nm. Also, the present invention provides a production method for cosmetic tissue comprising: a first step of obtaining a composition comprising microemulsion particles of no more than 5,000 nm; a second step of coating the composition onto a tissue substrate; and a third step of drying the composition, and the present invention provides a method of using same. According to the present invention, after the skin has been cleaned, removal of the remaining water fraction and coating of a dermatological beauty composition are carried out in one go, thereby allowing easy-to-use and effective cosmetic enhancement to the skin.

Abstract: A Personal care 100% plant derived, biodegradable solid granules that sustain beneficial essential oils, and or plant/herbal extracts and emulsify in hot water to create an emulsified therapeutic solution is disclosed. This invention improves over existing liquids in that it's solid granule form is completely plant derived and biodegradable and can sustain essential oils and antioxidants without the requirement of chemical preservatives, and can be packaged in eco-friendly, compostable paper. It improves over existing solid forms in that it is a 100% water soluble granule that emulsifies easily in hot water to form an easy to use liquid product.

Abstract: The present disclosure is directed to dispersions of a Dead Sea material in oil, the Dead Sea material is present in the dispersions in the form of solid nanoparticles. Further disclosed are formulations comprising the dispersions, method of treating and/or preventing diseases or disorders of the skin comprising topical application of the dispersions or formulations thereof onto a skin of a subject, method of inducing a heat sensation on the skin of a subject by topically applying the dispersions or formulations thereof onto a skin of a subject and methods of preparing the dispersions.

Abstract: Foil-type applicator for the selective lightening of keratin fibers, particularly human hair, and use of the applicators for producing targeted lightening effects on the hair.

Abstract: The present invention relates to improved powderous formulations comprising a high amount of at least one organic acids or esters having an aromatic ring system, as well as to the production of such formulations.

Abstract: Oral and dental care and cleaning agents are provided for use with an electric toothbrush. The oral and dental care and cleaning agent includes at least one polishing agent and at least one surfactant. A weight ratio of the at least one polishing agent to the at least one surfactant is less than or equal to six.

Abstract: The present invention relates to a topical composition comprising at least one collagen protecting and/or collagen enhancing agent and a silica-titanium dioxide composite particle having a particle size Dv0 of greater 0.3 ?m, a Dv100 of less than 35 ?m and a Dv50 of 4.0 to 10 ?m, wherein the silica-titanium dioxide composite particle consists of 20-45 wt.-% titanium dioxide particles having a particle size Dv50 of 100 to 300 nm embedded in a matrix of silica. Furthermore the invention relates to the use of such silica-titanium dioxide composite particles to ameliorate the sensory properties of a topical composition comprising collagen protecting agent and/or collagen enhancing agent as well as to reduce the short and long term eye contour puffiness, dark eye circles, crow's feet and fine lines.

Abstract: The invention relates to a liquid personal cleaning composition. The present inventors have found that inclusion selected di or tricarboxylic acid or a salt thereof, when combined with thymol or terpineol provide synergistic antimicrobial action in a rapid fashion and such efficacy is very low concentrations of thymol and/or terpineol.

Abstract: The present invention relates generally to the field of enhancing skin appearance. One aspect of the invention aims to provide a composition comprising 4-oxo-2-pentenoic acid for use in the reduction or prevention of regions of the skin with darker pigmentation. The present invention also relates to cosmetic use of a composition comprising 4-oxo-2-pentenoic acid for the reduction or prevention of regions of the skin with darker pigmentation.

Abstract: Compositions containing octocrylene, octinoxate, octisalate, homosalate and having improved sun protection factor (SPF) properties, as well as methods of improving sun protection factor (SPF) properties of compositions, are provided.

Abstract: The invention relates generally to liquids such as mouth rinses for the prevention and elimination of bad breath as well as for the reduction of oral microorganisms responsible for the development of dental plaque and tooth decay. In particular, the present invention relates to a method of preparing non-alcohol or reduced alcohol mouth rinses effective at preventing the above-mentioned problems.

Abstract: A method of solubilizing a composition, such as an organic manufactured photochromic dye that is free of carcinogens, non-mutagenic, non-toxic to human skin in any concentration, and suitable for application to, and absorbable by, human skin. The photochromic dye is suitable to be applied directly to human skin, and which dye is configured to indicate exposure to UV rays. The composition is configured to change color upon exposure to UVA, UVB and/or UVC rays. The composition can be used with other compositions, such as sunscreen, and be applied to human skin prior to application of the sunscreen, or, formulated with the sunscreen such that when the active ingredients of the sunscreen diminish, the photochromic dye will change color to generate a visual indicator of this condition.

Abstract: Methods of producing lignin peroxidase are provided. Also provided are methods and cosmetic compositions suitable for skin and hair lightening as well as kits and an article-of manufacturing including active ingredients for skin and hair lightening.

Abstract: The present invention provides cosmetic formulations for improving the appearance of the skin, including the facial area. The compositions of the invention provide multiple enhanced technologies that work synergistically to enhance hydration and appearance of the skin. Anti-aging peptides and tissue respiratory factor work together in an HA rich environment to enhance collagen and elastin while beneficial antioxidants protect HA in the skin from damaging exposure.

Abstract: The present invention relates to a hair care product. In particular, the invention relates to an apple cider vinegar hair texturizing rinse product.

Abstract: A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously in a dosing regimen which includes one or more loading doses administered at shortened intervals as compared to dosing at steady-state is disclosed. In certain embodiments, the dose of tramadol is from about 45 mg to about 80 mg and the second (and optionally) third doses are intravenously administered at intervals of from about 2 to about 3 hours, and thereafter the tramadol is intravenously administered at a dosing interval of about 4 to about 6 hours, until the patient no longer requires treatment with tramadol. In preferred embodiments, the intravenous dosing regimen provides a Cmax and AUC of tramadol is similar to the Cmax and AUC of an oral dose of 100 mg tramadol HCl given every 6 hours.

Abstract: Aqueous formulations that include at least one active pharmaceutical ingredient; and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100 s?1 and a temperature of 25° C.; a surface tension that is not greater than 60 dynes/cm when measured under ambient conditions; or a contact angle on a medical grade polymeric material of 50° or greater when measured under ambient conditions. Methods of coating and coated microneedle arrays using the aqueous formulations are also disclosed herein.