Abstract: A patient monitoring system includes at least two wireless sensing devices, each configured to measure a different physiological parameter from a patient and wirelessly transmit a parameter dataset. The system further includes a receiver that receives each parameter dataset, a processor, and a monitoring regulation module executable on the processor to assign one of the at least two wireless sensing devices as a dominant wireless sensing device and at least one of the remaining wireless sensing devices as a subordinate wireless sensing device. The physiological parameter measured by the dominant wireless sensing device is a key parameter and the parameter dataset transmitted by the dominant wireless sensing device is a key parameter dataset. The key parameter dataset from the dominant wireless sensing device is processed to determine a stability indicator. The subordinate wireless sensing device is then operated based on the stability indicator for the key parameter.

Abstract: According to certain inventive techniques, a blood pressure recording device includes at least one blood pressure sensor, a display configured to visually present received data, a wireless transceiver, a memory storing a reminder time, and a processor including a clock. The processor is configured to: receive blood pressure data from the at least one blood pressure sensor; process the blood pressure data to form a systolic reading and a diastolic reading; transmit the systolic reading and the diastolic reading to the display for visual presentation to a user; transmit the systolic reading and the diastolic reading to the wireless transceiver for wireless transmission; retrieve the reminder time from the memory; compare the reminder time to a time of the clock; and generate an alert when the clock time is equal to the reminder time.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: An intra-body communication system for monitoring physiological changes in a patient is provided. The system can include a first device implanted into a patient's body; a second device spaced apart from the first device; and a receiver for detecting and/or decoding the signals to monitor physiological changes in the patient. The first device and second device are capable of engaging in a two-way communication through transmission of one or more signals through at least a portion of the patient's body between the first device and the second device. In one embodiment, the signal may be an optical signal.

Abstract: In one aspect, an elastography system includes an elastography device and a position sensing device connected to the elastography device. The elastography device includes a housing, a probing element removably attached to the housing, and a force sensor attached within the housing, where the force sensor is connected to the probing element. In another aspect, an elastography) method includes inserting a probing element into a material, producing, by a force sensor connected to a base of the probing element a signal indicative of a force applied to the probing element upon insertion of the probing element into the material, and based on the signal, deriving a mapping of spatial variations of a material property within the material.

Abstract: A method of luminance lifetime imaging includes receiving incident photons at an integrated photodetector from luminescent molecules. The incident photons being received through one or more optical components of a point-of-care device. The method also includes detecting arrival times of the incident photons using the integrated photodetector. A method of analyzing blood glucose includes detecting luminance lifetime characteristics of tissue using, at least in part, an integrated circuit that detects arrival times of incident photons from the tissue. The method also includes analyzing blood glucose based upon the luminance lifetime characteristics.

Abstract: A system includes a wearable head apparatus and an electronic console. The head apparatus is configured to receive resultant light from the head of a subject. The electronic console includes a fiber array, a detector, and a computing device. The fiber array includes a plurality of fibers configured to transport resultant light received by the head apparatus. The detector includes a plurality of super-pixels each defined by a plurality of pixels of an array of pixels. Each super-pixel is associated with a fiber. Each super-pixel is configured to generate a plurality of detection signals in response to detected resultant light from its associated fiber. The computing device receives the detection signals from each of the plurality of super-pixels. The computing device generates a high density-diffuse optical tomography (HD-DOT) image signal of the brain activity of the subject based on the detection signals from the super-pixels.

Abstract: An observation device includes a light source unit capable of adjusting a quantity of 390-490 nm illuminating light according to a B1 range and a B2 range having a longer wavelength than the B1 range, and an imaging element that images reflected light from a subject irradiated with illuminating light. The light source unit changes the light quantity ratio of the B1 range to the B2 range depending on whether white light imaging is conducted or narrow band imaging is conducted. The imaging element includes RGB color filters arranged according to pixels and the R color filter transmits more light in an R range and the B1 range than light in the second B range and has a spectral characteristic that satisfies a predetermined conditional formulae.

Abstract: This photo-acoustic imaging device (100) is provided with: light emitting diodes (16); an acoustic wave detecting unit (14); a device main body (2) in which a light source driving unit (22) including a power supply unit (22a) and a signal generating unit (22b) is provided; and a coaxial cable (3). For the coaxial cable (3), an external conductor (3c) of the coaxial cable (3) is connected to the power supply unit (22a) and an internal conductor (3a) of the coaxial cable (3) is connected to the signal generating unit (22b).

Abstract: An apparatus, system, and method for monitoring a person suffering from a chronic medical condition predicts and assesses physiological changes which could affect the care of that subject. Examples of such chronic diseases include (but are not limited to) heart failure, chronic obstructive pulmonary disease, asthma, and diabetes. Monitoring includes measurements of respiratory movements, which can then be analyzed for evidence of changes in respiratory rate, or for events such as hypopneas, apneas and periodic breathing. Monitoring may be augmented by the measurement of nocturnal heart rate in conjunction with respiratory monitoring. Additional physiological measurements can also be taken such as subjective symptom data, blood pressure, blood oxygen levels, and various molecular markers. Embodiments for detection of respiratory patterns and heart rate are disclosed, together with exemplar implementations of decision processes based on these measurements.

Abstract: An apparatus includes a sensing circuit configured to generate a sensed physiological signal that includes physiological information of a subject, a detection circuit, and a control circuit. The detection circuit detects a physiological condition of a subject using the physiological signal. The control circuit stores sampled values of a segment of the physiological signal in temporary memory storage; and stores the sampled values in non-temporary storage in response to receiving an indication of continued detection of the physiological condition.

Abstract: A system (100) for assessing a subject at risk of a soft tissue abnormality such as deep vein thrombosis (DVT), comprises a motion sensor (108) which is adapted to be fixed, in use, to a muscle (106) of the subject. The motion sensor includes a transmitter (206) configured to transmit a signal (400) representing motion of the sensor. A receiver (118) is configured to receive the signal from the transmitter of the motion sensor. A signal processor (112) is coupled to the receiver and configured to analyse first and second data sets received via the receiver from the motion sensor. The first and second data sets represent respective first and second oscillatory mechanical responses of first and second muscles of the subject resulting from mechanical stimuli. The analysis comprises determining first and second parameter sets characterising the first and second oscillatory mechanical responses, and comparing the first parameter set with the second parameter set to assess a possible presence of DVT in the subject.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: Medical devices can perform a plurality of functions, such as sensing, monitoring, deriving and/or calculating various physiological statuses of a patient (e.g., blood pressure, temperature, respiration rate, etc.). Medical devices can also be used to image part or all of a patient's body, to deliver a treatment, or to manage information related to a patient's care. The present disclosure is directed at one or more devices that perform these functions using a plurality of processing circuits, wherein each processing circuit has a timing circuit with a local clock. These processing circuits can be connected via a network, and each timing circuit can communicate with at least one other timing circuit in order to detect and correct time-differences between their local clocks. In this way, multiple processing circuits can be synchronized with each other to facilitate diagnosis or treatment of a patient's condition, or other aspects of a patient's care.

Abstract: A measurement apparatus includes a contact unit for contacting with a test site, a biological sensor for acquiring a biometric output from the test site, an inclination detection unit for detecting an inclination of the measurement apparatus, and a controller. The controller generates biological information based on the biometric output from the biological sensor when the inclination detected by the inclination detection unit falls within a predetermined angular range in a state where the test site is in contact with the contact unit while supporting the measurement apparatus in an inclining manner.

Abstract: Diffuse optical flow (DOF) sensors can be used to assess deep tissue flow. DOF sensors positioned on a foot can provide fluctuating light intensity data to an analyzer, which can then determine absolute and/or relative blood flow. The determined absolute and/or relative blood flow can be signaled to an operator, for example a surgeon for intra-operative use. DOF sensors may be utilized to assess pedal revascularization, for example to guide interventional procedures and to evaluate their efficacy. A support structure can carry a plurality of DOF sensors, such that when the support structure is placed onto a patient's foot, the DOF sensors are disposed adjacent different locations on the foot. The different locations may correspond to different topographical regions of the foot, for example different pedal angiosomes.

Abstract: A measuring apparatus for measuring skin perfusion pressure of an examined region in a subject, the measuring apparatus including: a measuring device configured to measure blood flow in the examined region; a detection unit configured to detect a height of the examined region; and a processing unit configured to determine the skin perfusion pressure of the examined region on the basis of a change in the blood flow in the examined region measured by the measuring device with the height of the examined region being changed and the height of the examined region being detected by the detection unit.

Abstract: A blood pressure cuff assembly for an ambulatory blood pressure monitor may include a hollow cuff and an elastic liner provided on the reverse side of the cuff. An airbag may be provided in the cuff. A first connection part and a second connection part may be provided on the cuff. A third connection part and a fourth connection part may be correspondingly provided on the liner. The effect of tight inside and loose outside is achieved by the combination of the elastic liner and the cuff. When worn on an upper arm, the elastic liner has an elastic deformation and consequently tightens around the upper arm so as to realize certain slip resistance, and the cuff will not slip down even tied a bit loosely when located on the upper arm. The feeling of constraint from the cuff is reduced significantly and the comfort is improved.

Abstract: A vital signs monitoring system which comprises at least one optical vital signs sensor (100) configured to measure or determine vital signs of a user and to output an output signal. Said optical vital signs sensor (100) comprises at least one laser light source (110) configured to generate laser light, which is directed towards a skin (1000) of a user, and at least one photo detector unit (120) configured to detect light which is indicative of an absorption or reflection of the laser light from the at least one light source (100) in or from the skin (1000) of the user.

Abstract: In various examples, a stimulation needle apparatus is used for selectively administering a trial stimulation to body tissue of a patient. The stimulation needle apparatus includes a cannula assembly including a cannula and a cannula hub disposed at a proximal cannula end. A stylet assembly includes a stylet sized and shaped to fit within a cannula lumen. A stylet hub is disposed at the proximal stylet end and is configured to engage with the cannula hub. With the stylet hub engaged with the cannula hub, the distal stylet end extends distally from the distal cannula end. A stylet connection is electrically coupled with the stylet and is configured to electrically couple with a stimulator device, such that, a stimulation pulse delivered by the stimulator device is conducted from the stylet connection through the stylet to the distal stylet end to administer the trial stimulation.

Abstract: A controller-based apparatus for diagnosis and treatment of a subject with acquired brain injury and dysfunction. Various embodiments of the invention described herein recognize that different body postures affect the autonomic nervous system differently, and therefore various external stimuli may have different therapeutic efficacies when a patient or subject is in each body posture. Postures, such as walking, sitting, standing, prone and supine, have different effects on the autonomic nervous system, and therefore some stimuli have different physiological efficacies while a patient or subject is in a given body posture. Disclosed embodiments of the present invention leverage this relationship to provide a controller-based apparatus that determines a combination of posture and stimulus that has optimal therapeutic effect, while minimizing health practitioner involvement.

Abstract: A method of monitoring the cardiac function of a patient includes receiving a position input from a position sensor attached to the patient and classifying the position input into a position class. Cardiac waveform data is received for the patient and then the cardiac waveform data is compared to model waveform parameters for the position class.

Abstract: A method and system for visualization of electrophysiology information sensed by electrodes on a catheter, includes recording times of electrode signal acquisition, designating a reference electrode signal acquisition, assigning a relative time to each recorded time of electrode signal acquisition relative to the reference electrode signal acquisition, identifying the electrodes with signal acquisition, correlating assigned relative times to identified electrodes to generate a sequence of electrode signal acquisitions, and generating a visual representation of the sequence of electrode signal acquisitions generating a visual representation with a graphical image of the electrodes, wherein individual electrodes are visually marked to represent the sequence of electrode signal acquisitions.

Abstract: A preferred conformal penetrating multi electrode array includes a plastic substrate that is flexible enough to conform to cortical tissue. A plurality of penetrating semiconductor micro electrodes extend away from a surface of the flexible substrate and are stiff enough to penetrate cortical tissue. Electrode lines are encapsulated at least partially within the flexible substrate and electrically connected to the plurality of penetrating semiconductor microelectrodes. The penetrating semiconductor electrodes preferably include pointed metal tips. A preferred method of fabrication permits forming stiff penetrating electrodes on a substrate that is very flexible, and providing electrical connection to electrode lines within the substrate.

Abstract: Systems and methods of the present invention provide for storing an annotated set of confirmed epileptiform discharges (ED) waveforms in a database; receiving, by a computing device, a signal encoding electroencephalograph (EEG) data from a plurality of electrodes each attached to a subject and detecting EEG data; generating a user interface displaying a plurality of waveforms based upon at least a portion of the EEG data; receiving an initial selection of a portion of one of the plurality of waveforms comprising an ED; identifying a list of candidate waveforms including potential EDs by determining an alignment of the initial selection with a portion of one of the plurality of waveforms in the EEG data; displaying the list of candidate waveforms on the user interface; receiving, from the user and via the user interface, an identification of a subset of the list of candidate waveforms; and storing the subset of the list of candidate waveforms as an annotated list of confirmed EDs in the database.

Abstract: An electric conductive sensing device is provided. A front sheet of a sensing pad has several openings. A sensing electrode is a conductive ink electrode aligned with and exposed through each opening. Several first terminals are formed on an insert portion of the sensing pad and are connected to sensing electrodes. Each opening covered by a conductive gel is electrically connected to the corresponding sensing electrode. The insert portion is integrated in a connector. The present invention can be used as electrode patches of ECG devices or electric stimulators. In use, the connector is plugged into the devices to transmit tiny electrical currents to the ECG device from human skin surface, or to transmit electrical currents generated from the stimulator to human. The sensing electrodes are formed by conductive ink printing thereby simplifying the manufacturing process and lowering the manufacturing cost compared to conventional soldered structures.

Abstract: Embodiments of a method for removal and replacement of artifacts in electrophysiological data from muscular activity in the a gastrointestinal tract of a patient are disclosed. The approach includes setting an artifact identification threshold based on the parameters of the data, assessing the full extent of the artifact in time, and replacing the values with ones that are neutral in the time series and minimizing the effect on a power spectrum of the data. More particularly, the method includes steps of identifying artifacts within the raw time series data, eliminating the identified artifacts, and replacing the artifacts with any of interpolated points or constant value points to create a clean time series data set representing valid gastrointestinal tract EMG signals.

Abstract: Embodiments relate to acquiring magnetic resonance (MR) images with suppressed residual blood signal in the early cardiac phases, leading to images with a preferred dark-blood appearance throughout the entire cardiac cycle, which improves accuracy of subsequent post-processing algorithms. The acquisition of the desired blood suppressed tissue images is achieved through a double inversion recovery pulse in DENSE sequences. The double inversion recovery pulse is applied after an electrocardiogram (ECG) trigger at a beginning point of a repetition time period, followed by a displacement encoding module at an inversion time during the repetition time period and a readout module comprised of a plurality of frames during a remainder of the repetition time period. The displacement encoding module applies a labelling process on the tissue, while the readout module applies an un-labelling process. The readout module comprises an imaging sequence adapted to acquire DENSE images.

Abstract: In a method and magnetic resonance (MR) apparatus for determining a fraction of scar tissue in the myocardium of an examination person, magnetization of nuclear spins is prepared by radiation of a preparation pulse in the myocardium, and MR signals are acquired for multiple MR images while the magnetization returns to equilibrium. The multiple MR images are brought into registration with each other, so a movement of the heart between MR images is compensated. T1 times are determined using this sequence of compensated MR images. Different MR template images with different contrasts are calculated at different times after radiation of the preparation pulse, using the calculated T1 times. A myocardial contour is determined using one of the template images that has a first contrast. Scar tissue in the myocardium is determined using another template image that has a second contrast that differs from the first contrast.

Abstract: A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample.

Abstract: The chronic nature of asthma necessitates regular self-monitoring of respiratory function in susceptible individuals, however the available devices for performing the necessary measurements are either inaccurate or expensive and bulky. The present invention provides a small, cheap spirometer for efficient, accurate and convenient measurement of breathing characteristics.

Abstract: Disclosed is a method and device for assessing respiratory data in a monitored subject. The disclosed method comprises collecting respiratory data of the subject at different levels of exertion with a physiological monitoring system (15-19), the respiratory data at least relating to instantaneous lung volume and comprising the end expiratory lung volume (EELV) after expirations; collecting exertion level data of the subject at the different levels of exertion, the exertion level data at least relating to instantaneous oxygen demand and/or heart rate; establishing a parametric relation (14, 15) between the collected respiratory data and the collected exertion level data, the parametric relation being described by one or more parameters; and assessing the respiratory data of the subject in terms of the value of the one or more parameters. The method and device allow a reliable measuring of dynamic hyperinflation in subjects without requiring much attention on the part of the subject.

Abstract: A method of detecting, measuring, logging, and tracking a user's consumption of liquid through an electronic wearable on a person's wrist, hand, or other extremity used for consuming beverages is described. In preferred embodiments, the electronic wearable can detect individual sips, the final sip of a beverage, and the type of container the beverage is being consumed from.

Abstract: The present invention describes methods and systems to enable a concerned party to continuously monitor the progression of a medical condition in one or more patients. The progression of the medical condition is determined by processing sensor data obtained from one or more physiological and/or motion sensors and survey data obtained from the patients. Further, environmental data such as air quality, temperature and humidity may also be used along with the sensor data and the survey data to monitor/track the progression of the medical condition.

Abstract: A method and apparatus implementing a tele-rehabilitation system with remote supervision via wireless telecommunication means is disclosed. The method for assisting a user performing musculoskeletal movement in rehabilitation exercise comprises of motion-sensing a first part of user's body to be exercised (e.g. upper or lower limb), and motion-sensing a second part of user's body not intended to be moved (e.g. trunk or neck) during the first part of user's body being exercised. The method includes alerting the user of undesirable movements (i.e. compensation) sensed in the trunk or neck in real-time and with biofeedback to the user. The sensors transmit data wirelessly (e.g. via Bluetooth) to be processed and/or stored by a computing device nearby such as a tablet, smart-phone or laptop, and processes the data for efficient visual representation of the rehabilitation exercise. The method also captures video recordings of the user performing the exercises for review by the supervising therapist.

Abstract: A system and method for reducing intrafractional motion of a subject The system includes a subject user device, whereby the user device includes an image acquisition device configured to receive location marker information of the subject to provide location marking data of the subject. The system may also include a digital processor configured to: receive the location marking data and determine movement of the subject relative to the location marker information; and communicate feedback of the movement to the subject to help the subject reduce intrafractional motion.

Abstract: The invention provides a patient monitoring system for monitoring a patient in a bed. A video camera is used for capturing video images of the patient. Video analysis is used to determine and track the position of body parts of the patient including the hands. This analysis is enhanced by using sensors which detect interaction by the patient with pieces of equipment in the vicinity of the bed.

Abstract: A method and system is provided for finding and analyzing gait parameters and postural balance of a person using a Kinect system. The system is easy to use and can be installed at home as well as in clinic. The system includes a Kinect sensor, a software development kit (SDK) and a processor. The temporal skeleton information obtained from the Kinect sensor to evaluate gait parameters including stride length, stride time, stance time and swing time. Eigenvector based curvature detection is used to analyze the gait pattern with different speeds. In another embodiment, Eigenvector based curvature detection is employed to detect static single limb stance (SLS) duration along with gait variables for evaluating body balance.

Abstract: Joint analysis system for analyzing kinematics of an anatomical including a sensor device, a storage device, a magnet, and an analysis engine. The sensor device can be configured to be disposed on a first side of the joint and can have one or more sensors, a processor coupled to the one or more sensors, a wireless data transmitter coupled to the processor, a data storage device coupled to the processor, and a battery coupled to the sensors, processor, wireless data transmitter, and data storage device. The magnet can be configured to be disposed on the second side of the joint. The analysis engine can be configured to receive data from the sensors.

Abstract: Embodiments of apparatuses and methods for detecting a spoof finger are disclosed. In one embodiment, an ultrasonic fingerprint sensor comprises an ultrasonic transmitter configured to transmit an ultrasonic wave to a finger, an ultrasonic sensor array configured to receive a reflected ultrasonic wave from the finger, and a controller configured to determine a reflected acoustic energy of the finger based on a difference between average amplitudes of the reflected ultrasonic wave from ridges and valleys of the finger; and determine whether the finger is a spoof based at least in part on the reflected acoustic energy of the finger.

Abstract: An audiometer comprising: a database storing a non-transitory digital test signal associated with a desired test sound; a digital to analog converter (DAC) that converts the digital test signal to an analog signal; headphones that produce a sound responsive to the analog signal; a microphone that registers the sound; and a controller that adjusts the digital test signal so that the sound produced by the headphones has acceptable fidelity relative to the desired test sound to have the sound be useable in a hearing test.

Abstract: A system and method for measuring glucose levels in a user's blood without having to draw a blood sample. A wave energy source emits wave energy. A modified ceramic coaxial resonator is provided that receives the wave energy and produces a frequency oscillation. An opening is formed in a conductive layer surrounding the ceramic coaxial resonator. Skin tissue is pressed against the opening. The sample tissue alters the frequency oscillation created by the ceramic coaxial resonator. At least some of the altered frequency oscillation is indicative of blood glucose levels within the sample tissue.

Abstract: Systems and electronic processes for reducing electronic alarms in a medical patient monitoring system. For example, a system for reducing electronic alarms can include an optical sensor and one or more hardware processors in electronic communication with the optical sensor. The one or more hardware processors can be programmed to measure oxygen saturation values of a patient over a first period of time, determine if at least one oxygen saturation value obtained over the first period of time exceeds a first alarm threshold, determine whether a first alarm should be triggered based on the determination that the at least one oxygen saturation value obtained over the first period of time exceeds the first alarm threshold, determine a second alarm threshold to be applied during a second period of time subsequent to the first period of time, the second alarm threshold replacing the first alarm threshold.

Abstract: A cover for a user's finger tip that includes: a cylindrical body; a closed end; and an opening, where the opening is adapted to receive the user's fingertip. The cover for the present invention is preferably used in a method for fingertip protection when using a oximeter, where the method includes the steps of: inserting a cover over a fingertip of a user, where the cover includes a cylindrical body, a closed end and an opening; placing a oximeter probe over the cover; removing the oximeter probe after a oximeter reading is taken; removing the cover from the user's fingertip; and discarding the cover.

Abstract: A medical device including a housing, and a diagnostic cartridge removably coupled to the housing, the diagnostic cartridge including a retractable needle mechanism disposed within the diagnostic cartridge, the retractable needle mechanism configured to extract a fluid sample, a fluid collection chamber disposed the retractable needle mechanism, the fluid collection chamber configured to collect the fluid sample extracted by the retractable needle mechanism, and a diagnostic chip disposed within the fluid collection chamber configured to analyze the fluid sample.

Abstract: A blood sampler device includes a sampler body forming a hollow internal chamber with upper and lower openings, the sampler body including a sealing device disposed adjacent to the upper opening. The blood sampler device further includes a blood collector adapted to be inserted into the sampler body, the blood collector including a plurality of capillary channels.

Abstract: A venipuncture assist device includes a main body having a first surface configured to confront a target venipuncture site. The device further includes a vein capture channel disposed within the first surface configured to urge a portion of a patient's tissue and subcutaneous vein therein when the vein capture channel is evacuated by vacuum, wherein the urging creates a bend in the vein for piercing by a venipuncture needle. The device further includes one or more needle channels extending from a front main body surface configured to receive and guide the needle into the bend in the vein.

Abstract: The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet.

Abstract: Embodiments of the present disclosure generally relate to apparatuses for sampling bodily fluids and methods of fabrication thereof. The apparatus includes at least one adhesive patch, at least one bodily fluid port attached to the adhesive patch, and at least one bodily fluid storing capillary connected to the bodily fluid port and attached to the adhesive patch. The adhesive patch may be adhered to a subject's skin, the input port may then be connected to a source of bodily fluids and the one or more bodily fluid storing capillaries function to draw in the bodily fluid over time and store it for later analyzation. The one or more bodily fluid storing capillaries may be formed by imprint lithography on a plastic or glass substrate.

Abstract: A biological information detection device according to an aspect of the present disclosure includes: a light source that, in operation, emits irradiation light for irradiating a test portion of a subject; a light detector that, in operation, detects light reached from the test portion and that outputs an electrical signal corresponding to the light; and a calculation circuit that, in operation, generates a signal of biological information related to a blood flow in a target area in the test portion based on the electrical signal. The light detector is an image sensor. The electrical signal includes an image signal obtained by the image sensor. The calculation circuit, in operation, detects a magnitude of an inclination of an orientation of the test portion with respect to a reference orientation by image recognition based on the image signal, and determines the target area according to the magnitude of the inclination of the orientation of the test portion.