Patents Issued in September 12, 2017
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Patent number: 9758722Abstract: The invention relates to Eu2+-activated phosphors, to a process of its preparation, the use of these phosphors in electronic and electro optical devices, such as light emitting diodes (LEDs) and solar cells and especially to illumination units comprising said magnesium alumosilicate-based phosphors.Type: GrantFiled: November 6, 2014Date of Patent: September 12, 2017Assignee: MERCK PATENT GMBHInventors: Aleksander Zych, Ralf Petry, Holger Winkler, Christof Hampel, Andreas Benker, Thomas Juestel
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Patent number: 9758723Abstract: To provide a novel up-conversion phosphor excellent in light-emitting properties, the up-conversion phosphor of the present invention is an up-conversion phosphor including, in a ZnMoO4-based matrix material thereof, Yb3+, at least one rare earth metal ion selected from the group consisting of Tm3+, Er3+ and Ho3+, and at least one monovalent metal ion selected from the group consisting of Li+, K+, Na+ and Rb+.Type: GrantFiled: October 23, 2015Date of Patent: September 12, 2017Assignee: GBRY CO., LTDInventor: Hom Nath Luitel
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Patent number: 9758724Abstract: Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape).Type: GrantFiled: October 8, 2015Date of Patent: September 12, 2017Assignees: INTELLIGENT MATERIAL SOLUTIONS, INC., THE TRUSTEES OF THE UNIVERSITY OF PHILADELPHIAInventors: Joshua E. Collins, Howard Y. Bell, Xingchen Ye, Christopher Bruce Murray
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Patent number: 9758725Abstract: There is provided a fluorescent material having a composition represented by the following Formula (1). (Sra,Bab,Eux,M11,M2e)SiOf·cMgO . . . Formula (1) (In the formula, M1 is at least one tertiary group element selected from Y and Tb; M2 is an alkali metal selected from Li, Na, and K; and 0<a<2, 0<b<2, 0?c<1, 0.001?d?0.06, 0?e?0.06, 0<x<0.1, and 3.7?f?4.1 are set.) Further, there is provided a light-emitting device including: the fluorescent material; and a light source irradiating the fluorescent material with excitation light to cause the fluorescent material to emit light.Type: GrantFiled: January 21, 2015Date of Patent: September 12, 2017Assignee: Ube Industries, Ltd.Inventors: Jin Amagai, Kouichi Fukuda
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Patent number: 9758726Abstract: Provided are a liquid crystal cell and a use thereof. An exemplary liquid crystal cell can be implemented in a bistable mode switching between a haze mode and a non-haze mode even with low driving voltage. Such a liquid crystal cell can be applied to various optical modulation apparatus, such as a smart window, a window protection film, a flexible display element, an active retarder for a 3D visual display, and a viewing angle-controlling film.Type: GrantFiled: July 11, 2014Date of Patent: September 12, 2017Assignee: LG CHEM, LTD.Inventors: Eun Jung Lim, Jung Woon Kim, Dong Hyun Oh
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Patent number: 9758727Abstract: The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula I in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.Type: GrantFiled: November 27, 2014Date of Patent: September 12, 2017Assignee: Merck Patent GmbHInventors: Kevin Adlem, Owain Llyr Parri, Rachel Tuffin, Patricia Eileen Saxton
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Patent number: 9758728Abstract: A combined hydrothermal liquefaction (HTL) and catalytic hydrothermal gasification (CHG) system and process are described that convert various biomass-containing sources into separable bio-oils and aqueous effluents that contain residual organics. Bio-oils may be converted to useful bio-based fuels and other chemical feedstocks. Residual organics in HTL aqueous effluents may be gasified and converted into medium-BTU product gases and directly used for process heating or to provide energy.Type: GrantFiled: May 13, 2013Date of Patent: September 12, 2017Assignee: Battelle Memorial InstituteInventors: Douglas C. Elliott, Gary G. Neuenschwander, Todd R. Hart
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Patent number: 9758729Abstract: The invention relates to continuous process for converting carbonaceous material contained in one or more feedstocks into a liquid hydrocarbon product, said feedstocks including the carbonaceous material being in a feed mixture including one or more fluids, said fluids including water and further liquid organic compounds at least partly produced by the process in a concentration of at least 1% by weight, where the process comprises converting at least part of the carbonaceous material by pressurizing the feed mixture to a pressure in the range 50-400 bar; heating the feed mixture to a temperature in the range 250-500° C., maintaining said pressurized and heated feed mixture in the desired pressure and temperature ranges in a reaction zone for a predefined time; cooling the feed mixture to a temperature in the range 25-200° C.Type: GrantFiled: June 11, 2012Date of Patent: September 12, 2017Assignee: STEEPER ENERGY APSInventor: Steen Brummerstedt Iversen
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Patent number: 9758730Abstract: The invention relates to a method to start up a Fischer-Tropsch process. A catalyst with a latent activity is used. The catalyst comprises titania, cobalt, promoter, and chlorine. The catalyst comprises more than 0.7 and less than 4 weight percent of the element chlorine, calculated on the total weight of the catalyst.Type: GrantFiled: July 14, 2014Date of Patent: September 12, 2017Assignee: SHELL OIL COMPANYInventors: Erwin Roderick Stobbe, Gerrit Leendert Bezemer, Peter John Van Den Brink, Alexander Petrus Van Bavel
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Patent number: 9758731Abstract: The present invention discloses a process for the conversion of phenolics into aromatic hydrocarbons. In more detail, the present invention refers to a process for the selective hydrodeoxygenation of phenolic feeds into aromatic hydrocarbons, such as benzene, toluene, alkylbenzenes and others. The selective catalytic hydrodeoxygenation is performed in absence of external supply of molecular hydrogen.Type: GrantFiled: December 10, 2013Date of Patent: September 12, 2017Assignee: STUDIENGESELLSCHAFT KOHLE MBHInventors: Roberto Rinaldi, Xingyu Wang
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Patent number: 9758732Abstract: The removal of poisonous metalloids from crude oil is a method of removing naturally occurring arsenic (As), antimony (Sb), and bismuth (Bi) from crude oil before the crude oil is processed through a refinery. The removal of poisonous metalloids from crude oil entails forming an emulsion comprising the crude oil and an inorganic salt or mineral acid solution prepared by recirculation and agitation. The agitation of the emulsion causes arsenic (As), antimony (Sb), and bismuth (Bi) containing compounds to dissolve in the inorganic salt or mineral acid solution. The crude oil is separated from the inorganic salt or mineral acid solution by settling. The treated crude oil has a poisonous metalloid concentration of less than 1 ppm making it acceptable for oil refining operations. Optionally, any inorganic salt or mineral acid solution remaining in the crude oil after separation can be removed using a silica gel dryer.Type: GrantFiled: September 24, 2015Date of Patent: September 12, 2017Inventor: Anuj K Saha
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Patent number: 9758733Abstract: An asphaltenes separation system comprising a flocculant feed system configured to add a flocculant to a production fluid to flocculate asphaltenes in the production fluid, and an asphaltenes separator configured to remove flocculated asphaltenes from the production fluid.Type: GrantFiled: October 16, 2015Date of Patent: September 12, 2017Assignee: ExxonMobil Upstream Research CompanyInventors: Payman Esmaeili, Jason W. Lachance, Brendon L. Keinath
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Patent number: 9758734Abstract: The hydroisomerization of a paraffinic hydrocarbon feedstock obtained from renewable sources is effectively achieved by passing the feedstock in the presence of hydrogen over a hydroisomerization catalyst comprising a crystalline metal silicate molecular sieve, in which a portion of the crystalline framework contains iron.Type: GrantFiled: March 10, 2014Date of Patent: September 12, 2017Assignee: BASF CorporationInventors: Ivan Petrovic, Ahmad Moini, Scott Hedrick, Martin Kraus
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Patent number: 9758735Abstract: Volatile organic compounds are removed from crude oil by adding an amount of stabilization energy to crude oil upstream of, or directly into, a crude oil stock storage tank or by recovering and condensing vapors from tank vent gas. Produced gas may be recovered as NGL in one or more cooling stages. Produced gas, whether partially recovered or not, may be used as fuel for the heater treater, other combustion device or compressed into a pipeline.Type: GrantFiled: March 19, 2015Date of Patent: September 12, 2017Assignee: ASPEN ENGINEERING SERVICES, LLCInventor: James M. Meyer
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Patent number: 9758736Abstract: A system includes a first steam injector configured to mix a steam and a feedstock to form a heated feedstock. Additionally, first viscosity of the feedstock is greater than a second viscosity of the heated feedstock. The system also includes a feed system positioned upstream of the first steam injector and configured to supply the feedstock to the first steam injector. In addition, the system includes a steam system configured to supply the steam to the first steam injector. Furthermore, the system includes a gasifier coupled to the first steam injector and configured to receive the heated feedstock.Type: GrantFiled: February 27, 2015Date of Patent: September 12, 2017Assignee: General Electric CompanyInventor: Luis Rogelio Granados
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Patent number: 9758737Abstract: A method to generate dense, multi-cyclic diamondoid fuels from bio-derived sesquiterpenes. This process can be conducted with both heterogeneous and homogenous catalysts and produces the targeted isomers in high yield. The resulting multi-cyclic structures impart significantly higher densities and volumetric net heats of combustion while maintaining low viscosities which allow for use at low temperature/high altitude. Moreover, bio-derived sesquiterpenes can be produced from renewable biomass sources. Use of these fuels will decrease Navy dependence on fossil fuels and will also reduce net carbon emissions.Type: GrantFiled: October 19, 2016Date of Patent: September 12, 2017Assignee: The United States of America as Represented by the Secretary of the NavyInventor: Benjamin G. Harvey
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Patent number: 9758738Abstract: A liquid fuel derived from processed biomass having extremely low water content and suitable for use in diesel engines or as an additive to petroleum based fuels, or which can be used as a petroleum or coal slurry substitute in those uses where a lower cost fuel have reduced emission is desired, is described.Type: GrantFiled: November 14, 2014Date of Patent: September 12, 2017Assignee: Permanente CorporationInventors: Marc Seidner, Leo Seidner, Hanya Seidner
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Patent number: 9758739Abstract: Cellulose and hemicellulose from biomass can be broken down to C6 and C5 sugars and further converted to corresponding sugar alcohols. It is now found that a new catalyst, MoS2, is active for the hydrogenation of sugar alcohols to hydrocarbons. Combining the technologies listed above allows us to convert the cellulose/hemicellulose to liquid hydrocarbons.Type: GrantFiled: January 30, 2014Date of Patent: September 12, 2017Assignee: PHILLIPS 66 COMPANYInventors: Madhu Anand, Jianhua Yao, Edward L. Sughrue
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Patent number: 9758740Abstract: A device for converting carbon dioxide in flue gas into natural gas using dump energy. The device includes a transformer and rectifier device, an electrolytic cell, a turbine, a carbon dioxide heater, a primary fixed bed reactor, a secondary fixed bed reactor, a natural gas condenser, and a process water line. An outlet of the transformer and rectifier device is connected to a power interface of the electrolytic cell, a gas-liquid outlet of a cathode of the electrolytic cell is connected to a gas-liquid inlet of a hydrogen separator, and a liquid outlet of the hydrogen separator is connected to a liquid reflux port of the cathode of the electrolytic cell.Type: GrantFiled: October 23, 2015Date of Patent: September 12, 2017Assignee: WUHAN KAIDI ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.Inventors: Yanfeng Zhang, Yilong Chen, Zhilong Wang, Zhangjian Fang, Xingcai Zheng
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Patent number: 9758741Abstract: The present invention is provided with: a first processing device main body (111) that processes carbonized coal (1) by means of processing gas (103) of which the oxygen concentration has been adjusted by blowers (113,115); a second processing device main body (121) that processes primary processed carbonized coal (2a), which results from being processed at the first processing device main body, by means of air (102) fed by a blower (122); a second-processing-gas state detection means that detects the state of the air used within the second processing device main body; and a control device (130) that, on the basis of information from the second-processing—gas state detection means, controls the blowers (113,115) in a manner so as to adjust the oxygen concentration in the processing gas when the state of the air has diverged from a predetermined state.Type: GrantFiled: September 30, 2013Date of Patent: September 12, 2017Assignee: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Keiichi Nakagawa, Setsuo Omoto, Fumiaki Sato
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Patent number: 9758742Abstract: The invention relates to the use of an O/W emulsion, in particular a PIT emulsion, for lubricating conveyor belt systems in food industries as well as a lubricant concentrate based on an O/W emulsion, in particular a PIT emulsion, of wax esters.Type: GrantFiled: December 21, 2015Date of Patent: September 12, 2017Assignee: Ecolab USA Inc.Inventors: Stefan Küpper, Christina Kohlstedde, Michael Schneider
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Patent number: 9758743Abstract: A lubricant composition of an oil of lubricating viscosity; an esterified copolymer with a backbone comprising units derived from (i) an ?-olefin monomer of at least about 6 carbon atoms and (ii) an ethylenically unsaturated carboxylic acid in a mole ratio of 1:3 to 3:1; and a polymer comprising olefin monomer units of 3 to 5 carbon atoms, wherein at least 50 percent by weight of such units contain fewer than 6 carbon atoms and wherein less than 5 percent by weight of such units are ethylene monomer units; exhibits good power transfer efficiency and elastohydrodynamic film thickness.Type: GrantFiled: February 14, 2013Date of Patent: September 12, 2017Assignee: The Lubrizol CorporationInventors: Daniel J. Knapton, William R. S. Barton, Brett Wessler, Mark R. Baker
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Patent number: 9758744Abstract: The present invention concerns a composition of matter comprising at least 85% w/w of (Z)-5,9-dimethyldeca-3,8-dien-5-ol and at most 15% w/w of (E)-5,9-dimethyldeca-3,8-dien-5-ol, as well as the use as perfuming ingredient of said composition of matter.Type: GrantFiled: April 28, 2015Date of Patent: September 12, 2017Assignee: Firmenich SAInventors: Alexandre Huboux, Robert Moretti
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Patent number: 9758745Abstract: In a process of making a liquid cleaning composition, adding a gel breaker upstream of an anionic surfactant addition in the recirculatory loop of a recirculatory batch processor mitigates the viscous hexagonal phase whilst providing maximum flexibility in formulating various ingredients in the composition.Type: GrantFiled: August 18, 2014Date of Patent: September 12, 2017Assignee: The Procter & Gamble CompanyInventors: Chong Gu, Vincenzo Guida, Geoffrey Marc Wise, Wei Dai, Bernie George Durham, Boon Ho Ng, Fang Hu
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Patent number: 9758746Abstract: The present invention provides a cleansing composition for a pump foamer that not only has excellent foam quality and low-temperature stability, but can also be easily rinsed away with a small amount of water. A cleansing composition to be dispensed by a pump foamer of the present invention is characterized by comprising: (a) 2 to 5 mass % of an ionic surfactant; and (b) 20 to 60 mass % of a polyhydric alcohol comprising propylene glycol; wherein at least 90 mass % of the (a) ionic surfactant is accounted for by a higher fatty acid soap having 5 to 25 carbon atoms, and an amount of propylene glycol contained in the (b) polyhydric alcohol is less than 20 mass % with respect to the entire composition.Type: GrantFiled: March 14, 2014Date of Patent: September 12, 2017Assignee: SHISEIDO COMPANY, LTD.Inventor: Takashi Meno
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Patent number: 9758747Abstract: Liquid or gel-form detergents can be externally structured with a structuring system comprising crystallizable glyceride(s) emulsified with an alkanolamine-neutralized anionic surfactant. Crystallizable glyceride(s) of use include hydrogenated castor oil. The liquid or gel-form detergents may be packaged in unit dose form.Type: GrantFiled: September 14, 2010Date of Patent: September 12, 2017Assignee: The Procter & Gamble CompanyInventors: Jean-Pol Boutique, Luc Marie Willy Lievens, Vincenzo Guida, Frederik Vandenberghe
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Patent number: 9758748Abstract: Articles of manufacture, such as paper towels, that contain polymer particles, for example water-soluble polymer particles, for example water-soluble soil adsorbing polymer particles and processes for making same are provided.Type: GrantFiled: March 20, 2014Date of Patent: September 12, 2017Assignee: The Procter & Gamble CompanyInventor: Charles William Neal
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Patent number: 9758749Abstract: The present invention relates to the field of perfumery. More particularly, it concerns short chain ?-sulfur carbonyl moieties capable of liberating an active molecule, such as a perfuming ?,?-unsaturated ketone or aldehyde. The present invention concerns also the use of said compounds in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds.Type: GrantFiled: September 5, 2014Date of Patent: September 12, 2017Assignee: Firmenich SAInventors: Andreas Herrmann, Peter Fankhauser
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Patent number: 9758750Abstract: A dishwashing composition which is a mixture of vinegar powder and lemon powder, or a mixture of vinegar powder, lemon powder and salt, for use in a dishwashing machine or for other cleaning purposes. The vinegar powder, lemon powder and, when present, salt can be mixed in any of a variety of proportions. The lemon powder, vinegar powder, and optional salt are non-toxic to humans and pets.Type: GrantFiled: September 26, 2016Date of Patent: September 12, 2017Inventors: George A. Gorra, Leila R. Gorra
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Patent number: 9758751Abstract: Aqueous hard surface cleaner compositions useful for removing permanent ink are disclosed. The compositions comprise 75 to 99 wt. % of water; 0.1 to 5 wt. % of a monoterpene; 0.1 to 5 wt. % of a C10-C17 fatty acid derivative; and 0.1 to 5 wt. % of one or more surfactants. The fatty acid derivative is selected from N,N-dialkyl amides, N,N-dialkyl esteramines, and N,N-dialkyl amidoamines. Preferably, a base such as sodium carbonate or monoethanolamine is also included. The invention includes concentrates comprising the non-aqueous components recited above, as well as other applications for the cleaners and concentrates such as graffiti removers and permanent ink erasers. The combination of a monoterpene and certain fatty acid derivatives, especially fatty N,N-dialkyl amides, unexpectedly enables even dilute aqueous compositions to rapidly decolorize black permanent marker from hard, non-porous surfaces.Type: GrantFiled: April 12, 2013Date of Patent: September 12, 2017Assignee: Stepan CompanyInventors: Aaron Brown, Wilma Gorman, Ronald A. Masters
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Patent number: 9758752Abstract: The invention concerns a method of producing an alcoholic beverage by fermentation having flavor and taste of passion fruit and grapefruit, characterized in that it comprises the following steps: providing a gas stream containing hydrogen sulfide, bubbling the gas stream containing hydrogen sulfide into a grape juice and/or grape juice derived fractions prior to yeast inoculation, and/or during fermentation. The alcoholic beverage obtainable by the method can be chosen from the group constituted by wines, beers and spirits. Most preferably, the alcoholic beverage is a Sauvignon Blanc wine.Type: GrantFiled: July 31, 2012Date of Patent: September 12, 2017Assignee: PERNOD RICARDInventors: Audrey Joyce Dorsey, William James Marfell, Frank Benkwitz, Michael Johannes Harsch, Andrew Frost
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Patent number: 9758753Abstract: In the beer-making process, the wort is treated with a processing aid which is a composite of Carrageenan and polyvinyl polypyrrolidone (PVPP).Type: GrantFiled: August 18, 2004Date of Patent: September 12, 2017Assignee: ISP INVESTMENTS LLCInventors: Mustafa Rehmanji, Chandra Gopal, Andrew Mola
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Patent number: 9758754Abstract: A cell separation and culture device having a porous substrate; and a patterned carbon powder layer having a plurality of hollow regions, formed on an upper surface of the porous substrate by a forming manner; wherein the thickness of the patterned carbon powder layer is 0.04-0.08 mm. The cell separation and culture device is able to separate, detect or culture cells with various size and shape. The cell separation and culture device of present invention also simplifies the process of cell separation, detection and culture; therefore, it is accomplished within a very short time.Type: GrantFiled: January 29, 2015Date of Patent: September 12, 2017Assignee: National Tsing Hua UniversityInventors: Da-Jeng Yao, Chih-Chung Chen
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Patent number: 9758755Abstract: A cell lysis workflow involving a cell suspension that is passed through a filter in a first flow direction from a first side of the filter toward a second side thereof. The filter captures a plurality of cells on the first side. A lysis solution is passed through the filter in a second flow direction opposite the first direction, thereby dislodging the plurality of cells captured on the filter, and resuspending the plurality of cells in the lysis solution on the first side of the filter. The lysis solution lyses the plurality of cells to produce a cellular lysate. The cellular lysate is passed through the filter in the first flow direction.Type: GrantFiled: October 23, 2015Date of Patent: September 12, 2017Assignee: LIFE TECHNOLOGIES CORPORATIONInventor: Philip Martin
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Patent number: 9758756Abstract: Methods of culturing microorganisms in combinations of phototrophic, mixotrophic, and heterotrophic culture conditions are disclosed. A culture of microorganisms may be transitioned between culture conditions over the life of a culture in various combinations, utilizing various conditions in a sequential manner to optimize the culture for growth or product accumulation.Type: GrantFiled: April 29, 2015Date of Patent: September 12, 2017Assignee: Heliae Development LLCInventors: Eneko Ganuza Taberna, Jason D Licamele, Anna Lee Tonkovich, Michael V Bellefeuille, Cameron Wyatt
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Patent number: 9758757Abstract: Provided are biomass-based materials and valuable uses of microalgal biomass including: (i) acetylation of microalgal biomass to produce a material useful in the production of thermoplastics; (ii) use of triglyceride containing microalgal biomass for production of thermoplastics; (iii) combination of microalgal biomass and at least one type of plant polymer to produce a material useful in the production of thermoplastics; (iv) anionization of microalgal biomass to form a water absorbant material; (v) cationization of microalgal biomass, and optional flocculation, to form a water absorbant material; (vi) crosslinking of anionized microalgal biomass; (vii) carbonization of microalgal biomass; and (viii) use of microalgal biomass in the making of paper.Type: GrantFiled: June 9, 2016Date of Patent: September 12, 2017Assignee: TERRAVIA HOLDINGS, INC.Inventors: Ali Harlin, Anna-stiina Jääskeläinen, Jani Kiuru, Christiane Laine, Tiina Liitiä, Kalle Nättinen, Jaakko Pere, Sonia Sousa, John Piechocki, Adrienne McKee, Jeffrey J. Cernohous, Adam R. Pawloski
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Patent number: 9758758Abstract: Described is an isolated strain of the fungus Colonostachys rosea termed BVT Cr-7 useful as a biological control agent for the treatment of plants. The isolated strain, formulations comprising said strain and/or spores derived from said strain may be applied to plants or plant materials in order to improve plant yield, to improve plant growth, or for the treatment or prevention of diseases or pathogens in the plant.Type: GrantFiled: September 11, 2014Date of Patent: September 12, 2017Assignee: Bee Vectoring Technology Inc.Inventors: John Sutton, Todd Gordon Mason
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Patent number: 9758759Abstract: This invention provides an Amycolatopsis sp. strain (zhp06), and a method of using the whole cell preparation of the strain for vanillin production. The strain was deposited in China Center for Type Culture Collection on Jul. 26, 2011 with the number of CCTCC NO: M 2011265. Under high concentrations of ferulic acid substrate, the vanillin production by this method can reach more than 10 g/L. The molar conversion rate of ferulic acid is more than 50% and the purity of vanillin is from 80% to 95%. The advantage of this invention includes: repeated use of biocatalyst cells, mild biotransformation condition, low environmental pollution, short production cycle, high product purity and simple purification procedure. It has a great potential for industrial applications.Type: GrantFiled: July 15, 2015Date of Patent: September 12, 2017Assignee: BGN TECH LLCInventors: Pu Zheng, Hui Li, Xinglin Wang, Jianhai Zhou, Shibiao Chu
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Patent number: 9758760Abstract: The invention provides methods of producing vaccines directed against microorganisms, with the methods comprising culturing, harvesting and/or suspending the microorganism in the presence of a radiation-protective composition and irradiating the bacteria or viruses with a dose of radiation sufficient to render the microorganism replication-deficient and/or non-infective. The radiation-protective compositions used in the methods of the present invention comprise at least one nucleoside, at least one antioxidant and at least one small peptide. The invention also provides methods of rendering bacteria in culture resistant to ionizing radiation (IR), with these methods comprising culturing the bacteria in the presence of a radiation-protective composition.Type: GrantFiled: December 8, 2015Date of Patent: September 12, 2017Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.Inventors: Michael J. Daly, Elena K. Gaidamakova
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Patent number: 9758761Abstract: A method of manufacturing and/or using a scaffold assembly for stem cell culture and tissue engineering applications is disclosed. The scaffold at least partially mimics a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation that uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct.Type: GrantFiled: April 13, 2015Date of Patent: September 12, 2017Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Lisa A. Scott Carnell, Emilie J. Siochi, Nancy M. Holloway, Kam W. Leong, Karina Kulangara
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Patent number: 9758762Abstract: A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprises culturing the adherent cells from the placenta or adipose tissue under 3 dimensional (3D) culturing conditions which allow cell expansion, the conditions comprising perfusion.Type: GrantFiled: August 20, 2013Date of Patent: September 12, 2017Assignee: Pluristem Ltd.Inventors: Moran Meiron, Amir Toren, Racheli Ofir, Nirit Drori-Carmi
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Patent number: 9758763Abstract: Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition.Type: GrantFiled: May 27, 2014Date of Patent: September 12, 2017Assignee: The Regents of the University of CaliforniaInventors: Irina M. Conboy, Michael J. Conboy, Hanadie Yousef, David V. Schaffer
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Patent number: 9758764Abstract: Described are embodiments that include methods and devices for separating composite liquids into components. Embodiments involve the use of a flexible membrane for separating a composite liquid into components. The composite liquid may include, in embodiments, a cellular containing liquid, such as whole blood or components of whole blood. In one specific embodiment, the composite liquid is a buffy coat.Type: GrantFiled: February 18, 2014Date of Patent: September 12, 2017Assignee: Terumo BCT, Inc.Inventors: James R. Ladtkow, Geoffrey M. Uhl, Jeremy P. Kolenbrander, Briden Ray Stanton
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Patent number: 9758765Abstract: Provided are a modified laminin having a cell-growth regulatory molecule bound to at least one site selected from the ? chain N-terminus, the ? chain C-terminus, the ? chain N-terminus and the ? chain N-terminus of laminin or a heterotrimeric laminin fragment, a method for culturing cells in the presence of the modified laminin, a method for establishing iPS cells in the presence of the modified laminin, and a culture substrate coated with the modified laminin. Human stem cells cultured in a xeno-free environment with the use of the modified laminin of the present invention can be provided as highly safe human stem cells applicable to regenerative medicine.Type: GrantFiled: April 9, 2012Date of Patent: September 12, 2017Assignees: OSAKA UNIVERSITY, KYOTO UNIVERSITYInventors: Kiyotoshi Sekiguchi, Yukimasa Taniguchi, Masato Nakagawa
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Patent number: 9758766Abstract: The present invention provides an artificial kidney precursor containing a non-human mammalian metanephros separated out from a living body, wherein the metanephros has been subjected to freezing and thawing treatments outside a living body, and contains mammalian mesenchymal stem cells transferred outside a living body, and a method of production thereof.Type: GrantFiled: December 9, 2014Date of Patent: September 12, 2017Assignees: OTSUKA PHARMACEUTICAL FACTORY, INC., JICHI MEDICAL UNIVERSITY, THE JIKEI UNIVERSITY, TOKYO WOMEN'S MEDICAL UNIVERSITYInventors: Eiji Kobayashi, Takashi Yokoo, Koutaro Kai
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Patent number: 9758767Abstract: Provided is a novel bacteriophage ?CJ22 (KCCM11364P). In addition, provided is an antibacterial composition containing the bacteriophage ?CJ22 (KCCM11364P) as an active ingredient. Further, provided is a method of preventing and/or treating infectious diseases caused by Clostridium perfringens in animals except for humans by using the bacteriophage ?CJ22 (KCCM11364P) or an antibacterial composition containing the bacteriophage ?CJ22 (KCCM11364P) as an active ingredient.Type: GrantFiled: February 26, 2014Date of Patent: September 12, 2017Assignee: CJ CHEILJEDANG CORPORATIONInventors: Bo Kyung Son, Gi Duk Bae, Jae Won Kim
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Patent number: 9758768Abstract: This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.Type: GrantFiled: March 23, 2015Date of Patent: September 12, 2017Assignee: INVISTA NORTH AMERICA S.A.R.L.Inventors: Alex Van Eck Conradie, Adriana Leonora Botes
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Patent number: 9758769Abstract: The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.Type: GrantFiled: May 13, 2016Date of Patent: September 12, 2017Assignee: REG LIFE SCIENCES, LLCInventors: Derek L. Greenfield, Elizabeth Clarke, Eli Groban, Vikranth Arlagadda, Sungwon Lee, Xuezhi Li, Zhihao Hu, Baolong Zhu
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Patent number: 9758770Abstract: Provided is an acid-resistant yeast cell that is genetically engineered to enhance activity of a radiation sensitivity complementing kinase, and a method of producing lactate by using the yeast cell.Type: GrantFiled: July 23, 2015Date of Patent: September 12, 2017Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Huisub Lim, Sungsoo Kim, Jiyoon Song, Soyoung Lee, Juyoung Lee, Kwangmyung Cho
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Patent number: 9758771Abstract: Provided are a beta prime subunit mutant of RNA polymerase, a microorganism of the Corynebacterium genus including a polynucleotide coding the same, and a method for producing L-lysine by culturing the same.Type: GrantFiled: June 24, 2014Date of Patent: September 12, 2017Assignee: CJ CHEILJEDANG CORPORATIONInventors: Sang Hee Park, Jun Ok Moon, Kwang Ho Lee