Patents Issued in September 21, 2017
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Publication number: 20170266621Abstract: A portable liquid-filtration device includes an inlet port, a filtering portion including a filtering medium and fluidly coupled to the inlet port, a filtered-liquid output port fluidly coupled to the filtering portion, a flush port fluidly coupled to the filtering portion, and a manually activated pump assembly fluidly coupled to the inlet port, filtering portion, output port and flush port. The pump assembly is configured, when activated, to create a negative fluid pressure at the inlet port and a positive fluid pressure at the output port and the flush port. As a consequence of activation of the pump assembly, the filtering portion receives unfiltered liquid from the inlet port, the output port receives from the filtering portion only liquid traversing the filtering medium in a first direction, and the flush port receives from the filtering portion liquid traversing the filtering medium in a second direction different from the first direction.Type: ApplicationFiled: November 24, 2015Publication date: September 21, 2017Inventor: Christopher Richard BARCHET
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Publication number: 20170266622Abstract: A water treatment device includes a sub-reverse osmosis membrane device having a primary casing and a primary reverse osmosis membrane dividing the primary casing into a primary liquid passing part and a primary permeating part; a low pressure water feed pump feeding seawater to the primary liquid passing part at a pressure that is equal to or lower than an osmotic pressure of the seawater; a main reverse osmosis membrane device having a secondary casing and a secondary reverse osmosis membrane dividing an inside of the secondary casing into a secondary liquid passing part and a secondary permeating part; and a high pressure water feed pump feeding a primary treated liquid, which is a resultant product of the seawater passing through and flowing out of the primary liquid passing part, to the secondary liquid passing part at a pressure higher than an osmotic pressure of the primary treated liquid.Type: ApplicationFiled: August 25, 2014Publication date: September 21, 2017Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Yoshiaki Ito, Hideo Iwahashi, Katsunori Matsui, Kiichi Tokunaga, Masanori Kawada
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Publication number: 20170266623Abstract: A method for preparing a graphene composite membrane on the surface of a tubular support. In the method, a tubular ceramic membrane is used as the support, a layer of graphene material is uniformly prepared on the surface of the support by vacuum suction, and the defect-free tubular graphene composite membrane is obtained by the drying process.Type: ApplicationFiled: August 27, 2015Publication date: September 21, 2017Inventors: Wanqin JIN, Kang HUANG, Gongping LIU
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Publication number: 20170266624Abstract: The invention provides a hollow fiber membrane exhibiting a favorable gas permeation performance and an excellent heat resistance in which the generation of pinholes are suppressed, and a hollow fiber membrane module using the same. The hollow fiber membrane comprising a gas permeable nonporous layer; and a porous supporting layer to support the nonporous layer formed of a thermoplastic elastomer having a DSC melting peak temperature of 130° C. or higher and a rupture elongation prescribed in ISO 37 (2010) of 300% or more.Type: ApplicationFiled: August 21, 2015Publication date: September 21, 2017Applicant: Mitsubishi Rayon Co., Ltd.Inventors: Noritaka SHIBATA, Kenjiro TAKAYANAGI
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Publication number: 20170266625Abstract: The present invention offers a forward osmosis composite hollow fiber membrane module having hollow fiber bundles comprising a plurality of hollow fibers, the hollow fibers having a separation layer composed of a macromolecular polymer thin film provided on the inner surface of a microporous hollow fiber supporting membrane, wherein the membrane area of the hollow fiber bundle is at least 1 m2, and a variation coefficient for the average thickness of the separation layer in the radial direction and the lengthwise direction of the hollow fiber bundles, as calculated by a method of measuring the mass of the separation layer portion in a scanning electron microscope image of a cross section of the separation layer in the thickness direction, is 0% to 60%.Type: ApplicationFiled: August 20, 2015Publication date: September 21, 2017Applicant: Asahi Kasei Kabushiki KaishaInventors: Akira Kiguchi, Tomoya Anan, Mikihiko Nakamura, Toshihiko Ohashi
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Publication number: 20170266626Abstract: The object of the present invention is to provide a porous membrane by which a useful component can be recovered while suppressing the clogging during filtration of a protein solution and from which only a small amount of an eluate is eluted even when an aqueous solution is filtered. The present invention provides a porous membrane containing a hydrophobic polymer and a water-insoluble hydrophilic polymer, the porous membrane having a dense layer in the downstream portion of filtration in the membrane, having a gradient asymmetric structure in which the average pore diameter of fine pores increases from the downstream portion of filtration toward the upstream portion of filtration, and having a gradient index of the average pore diameter from the dense layer to the coarse layer of 0.5 to 12.0.Type: ApplicationFiled: August 25, 2015Publication date: September 21, 2017Applicant: ASAHI KASEI MEDICAL CO., LTD.Inventors: Yuzo KAYAMA, Masayasu KOMURO, Tetsuya HAMASAKI
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Publication number: 20170266627Abstract: This specification describes an ion exchange membrane and a method of making it. The membrane may be used, for example, in an electrodialysis module or electrochemical cell. The membrane comprises an ion exchange polymer and inorganic particles preferably linked to the ion exchange polymer. To make a membrane, inorganic particles are mixed into an ion exchange membrane pre-cursor. A polymerization initiator or catalyst is then added and the resulting mixture is placed in a form and cured. The inorganic particles may comprise, for example, an oxidized form of graphite such as graphite oxide. The ion exchange polymer may comprise an ionic monomer, containing a quaternary ammonium group for anion exchange or a sulfonate group for cation exchange, along with a crosslinking co-monomer containing polymerizable diacrylic functionalities. The membrane is self-supporting and can be made without a supporting fabric.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Kai ZHANG, John H. BARBER, Russell James MACDONALD, Yongchang ZHENG, Li May GOH, Yan GAO, Yonghong ZHAO
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Publication number: 20170266628Abstract: The present invention includes a method of cleaning a membrane contactor comprising: connecting a membrane contactor having a first and a second surface, the membrane contactor being in liquid communication with a first and a second liquid circulation loop; rerouting the source of oil-containing liquid from the membrane contactor; draining the oil-containing liquid in contact with the first surface of the membrane contactor via a drain; circulating a cleaning oil over the first surface of the membrane contactor; pumping a collection fluid over the second surface of the membrane contactor; and contacting the oil-containing liquid with the first surface of the membrane contactor under pressure to maximize oil coalescence at the first surface of the membrane contactor while also circulating the collection fluid over the second surface of the membrane contactor to capture the coalesced oil.Type: ApplicationFiled: December 1, 2015Publication date: September 21, 2017Inventors: Peter B. Kipp, Stacy S. Truscott
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Publication number: 20170266629Abstract: The present invention provides a high-flux polyamide composite membrane, which includes a composite membrane body, wherein the composite membrane body includes a non-woven fabric, a porous supporting layer and a polyamide layer which are successively arranged; and the polyamide layer is prepared by a polyamine solution and a poly-acyl chloride solution through an interface polymerization reaction, wherein the polyamine solution contains amino acid. The amino acid adopted in the technical solution of the present invention can be used as an end-capping reagent to react with acyl chloride groups, thereby regulating a polyamide layer structure, decreasing a cross-linking degree of the polyamide layer, and opening a channel for the passing of water molecules; and moreover, the hydrophilic performance of a membrane surface can also be improved, and a water flux is increased while a high interception rate is ensured.Type: ApplicationFiled: June 7, 2017Publication date: September 21, 2017Inventors: BO PENG, HONGWEI LU, QUNHUI HU, HUI YU, PAN HE, JIN WANG, DAN LIU, CHUNQING WANG, PENGJUN LIU
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Publication number: 20170266630Abstract: The embodiment relates to beverage dispensing, and more particularly to the dispensing of a carbonated beverage, from any container into a vessel, providing a portion of the beverage as foam atop the dispensed beverage. To avoid the reduction of absorbed carbon dioxide in a carbonated beverage, increased atmospheric pressure is employed to move the beverage from the container through the apparatus and into the vessel. An oscillating means provides a sonic wave through the conduit and the liquid therein; the sonic wave initiates the reaction between the carbon dioxide and the ingredients in the beverage to cause the liquid to foam prior to dispensing into the vessel. Iterations include an adaptable apparatus for a beer tap and a means for passing the liquid to be dispensed through a permeable container filled with soluble material or a permeable container filled with a filtration means.Type: ApplicationFiled: May 5, 2015Publication date: September 21, 2017Applicant: Fizzics Group LLC.Inventors: David Arlen McDonald, Philip S. Petracca, William Scott Keeley
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Publication number: 20170266631Abstract: A material distributing and mixing apparatus A conduit having a fluid inlet and fluid outlet houses a mixing element The mixing element includes rectangular segments forming forward facing V-sections and rearward facing V-sections The forward facing V-sections form vertical apexes that face an incoming fluid stream while additive inlet ports are positioned proximate thereto.Type: ApplicationFiled: March 18, 2016Publication date: September 21, 2017Inventors: Robert Smith, Seungsuk Lee, Sameer Kshirsagar
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Publication number: 20170266632Abstract: A mixing device includes a base, shaft, impeller sleeve, and impeller blades. The base can be constructed for releasable attachment to an opening of a container, such as a 55-gallon drum. The shaft extends from the base and is coupled thereto such that rotation can be transmitted to the shaft by way of or through the base. The impeller sleeve is mounted on the shaft and supports the impeller blades. Each impeller blade includes an attachment leg and a stirring leg extending from the attachment leg. The impeller blades are supported so as to transition from a collapsed position with the stirring leg proximal to a central axis of the shaft to an extended position with the stirring leg distal from the central axis when the shaft is rotated. Each impeller blade can be formed of a plastic, such as a glass-filled polypropylene or glass-filled nylon.Type: ApplicationFiled: May 31, 2017Publication date: September 21, 2017Inventors: Douglas J. MATTSON, John F. GEE, Jeffrey R. SUSALLA, Ryan K. BERGMAN, Ronald R. RENKEL, JR.
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Publication number: 20170266633Abstract: An apparatus for generating one or several droplets of a first liquid in a second liquid immiscible with the first liquid includes a rotational body and a drive apparatus. The rotational body includes a fluid chamber, a fluid channel and a transition area. The transition area includes a first expansion area and a second expansion area. The drive apparatus is configured to provide the rotational body with such a rotation that the first liquid is supplied centrifugally to the fluid chamber and that centrifugally hydrodynamically induced pressure and lifting forces are caused due to the second expansion area, which cause a droplet break-off in the first liquid, such that a droplet of the first liquid embedded in the second liquid is generated.Type: ApplicationFiled: June 1, 2017Publication date: September 21, 2017Inventors: Frank SCHWEMMER, Friedrich SCHULER
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Publication number: 20170266634Abstract: Disclosed herein is an apparatus and method for growing a diamond. The apparatus for growing a diamond comprises: a reaction cell that is configured to grow the diamond therein; a main heater including a main heating surface that is arranged along a first inner surface of the reaction cell; and a sub-heater including a sub-heating surface that is arranged along a second inner surface of the reaction cell, the second inner surface being non-parallel with the first inner surface.Type: ApplicationFiled: June 1, 2017Publication date: September 21, 2017Inventors: Hexiang ZHU, Karl Pearson
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Publication number: 20170266635Abstract: A reactor design and configuration and a process for the catalytic dehydration of ethanol to ethylene where the reactor train is comprised of a multi-stage single reactor vessel or multiple reactor vessels wherein each stage and/or vessel has different length, internal diameter, and volume than the other stages and/or vessels and in addition the stages and/or reactor vessels are connected in series arrangement, preferably used with an improved means of introducing the ethanol feedstock and a heat carrying inert gas to the improved reactor train. The inert gas is heated in a separate furnace from the ethanol feed and then injected into the ethanol feed to supply the heat of reaction.Type: ApplicationFiled: March 24, 2017Publication date: September 21, 2017Applicant: Petron Scientech, Inc.Inventors: Yogendra Sarin, Brian Ozero, Frank Liotta, Hassan Taheri
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Publication number: 20170266636Abstract: A fuel synthesis catalyst of an embodiment for hydrogenating a gas includes at least one selected from the group consisting of; carbon dioxide and carbon monoxide, the catalyst comprising, a base material containing at least one oxide selected from the group consisting of; Al2O3, MgO, TiO2, and SiO2, first metals containing at least one metal selected from the group consisting of; Ni, Co, Fe, and Cu and brought into contact with the base material, and a first oxide containing at least one selected from the group consisting of; CeO2, ZrO2, TiO2, and SiO2 and having an interface with each of the first metals and the base material. The first metals exist on an outer surface of the base material, and on a surface of the base material in fine pores having opening ends on the outer surface of the base material and inside the base material. The first metals and the first oxide exist in the fine pores. The first metals have interfaces with the base material in the fine pores.Type: ApplicationFiled: March 13, 2017Publication date: September 21, 2017Applicant: Kabushiki Kaisha ToshibaInventors: Takayuki FUKASAWA, Kenji Essaki, Shinsuke Matsuno, Takashi Kuboki, Yasuhiro Goto, Seiichi SUENAGA
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Publication number: 20170266637Abstract: An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.Type: ApplicationFiled: June 2, 2017Publication date: September 21, 2017Applicant: CEM CORPORATIONInventors: JONATHAN MCKINNON COLLINS, JOSEPH JOSHUA LAMBERT, MICHAEL JOHN COLLINS
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Publication number: 20170266638Abstract: Provided are mixed metal oxy-hydroxides that serve as reactive media to bind, sequester, or alter one or more toxic chemicals such as sulfur dioxide (SO2), hydrogen cyanide (HCN), and others. A reactive media includes: a porous metal oxy-hydroxide including at least one first transition metal that is optionally one or more of copper, zinc, or iron; a second transition metal linked to the first transition metal by a bond that includes an oxygen, the second transition metal selected optionally being one or more of magnesium, calcium, cobalt, titanium, zirconium, aluminum, and silicon; and the metal oxy-hydroxide terminated by at least one hydroxyl group. The resulting media provides for excellent porosity and reactivity for removal of toxic chemicals from the environment or a sample.Type: ApplicationFiled: March 16, 2016Publication date: September 21, 2017Inventors: Joseph A. Rossin, Gregory W. Peterson, William F. Beuchter
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Publication number: 20170266639Abstract: The present invention generally relates to CO2-adsorbing, graphene-containing nanocomposites, methods of making the same, and methods of using the same.Type: ApplicationFiled: March 15, 2017Publication date: September 21, 2017Inventor: Alber Sadek
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Publication number: 20170266640Abstract: A process for producing water-absorbing polymer particles by suspension polymerization and thermal surface postcrosslinking, wherein the agglomerated base polymer obtained by suspension polymerization has a centrifuge retention capacity of at least 37 g/g and the thermal surface postcrosslinking is conducted at 100 to 190° C.Type: ApplicationFiled: November 24, 2015Publication date: September 21, 2017Applicant: BASF SEInventors: Tina Mark, Thomas Daniel, Erich Lutz, Stefan Molter, Anna Kowalski
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Publication number: 20170266641Abstract: Disclosed are a method of preparing a superabsorbent polymer, including adding a superabsorbent polymer with a water dispersion solution containing particles having i) a BET specific surface area of 300 to 1500 m2/g and ii) a porosity of 50% or more, and a superabsorbent polymer prepared by the method.Type: ApplicationFiled: October 14, 2015Publication date: September 21, 2017Applicant: LG Chem, Ltd.Inventors: Su-Jin Kim, Young-Sam Kim, Young-In Yang, Kyoung-Shil Oh
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Publication number: 20170266642Abstract: Embodiments of the present disclosure are directed towards methods for preparing mixed-metal oxide particles by heating adamantane-intercalated layered double-hydroxide (LDH) particles at a reaction temperature of from 400° C. to 800° C. to form mixed-metal oxide particles. The adamantane-intercalated LDH particles have a general formula [M1-xAlx(OH)2](A)x.mH2O, where x is from 0.14 to 0.33, m is from 0.33 to 0.50, M is chosen from Mg, Ca, Co, Ni, Cu, or Zn, and A is adamantane carboxylate, and an aspect ratio greater than 100. The aspect ratio is defined by the width of an adamantane-intercalated LDH particle divided by the thickness of the adamantane-intercalated LDH particle. The mixed-metal oxide particles comprise a mixed-metal oxide phase containing M, Al or Fe, and carbon.Type: ApplicationFiled: March 8, 2017Publication date: September 21, 2017Applicants: Saudi Arabian Oil Company, Durham UniversityInventors: Manohara Gudiyor Veerabhadrappa, Hugh Christopher Greenwell, Gasan Selman Alabedi, John Adrian Hall, Andrew Whiting
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Publication number: 20170266643Abstract: A method for preparing a transition-metal adamantane carboxylate salt is presented. The method includes mixing a transition-metal hydroxide and a diamondoid compound having at least one carboxylic acid moiety to form a reactant mixture, where M is a transition metal. Further, the method includes hydrothermally treating the reactant mixture at a reaction temperature for a reaction time to form the transition-metal adamantane carboxylate salt.Type: ApplicationFiled: March 8, 2017Publication date: September 21, 2017Applicants: Saudi Arabian Oil Company, Durham UniversityInventors: Manohara Gudiyor Veerabhadrappa, Hugh Christopher Greenwell, Gasan Selman Alabedi, John Adrian Hall, Andrew Whiting
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Publication number: 20170266644Abstract: An exhaust gas purification catalyst includes: a first catalyst unit that consists of a hydrogen generating catalyst including a noble metal and an oxide that contains lanthanum, zirconium and an additional element such as neodymium; a second catalyst unit that consists of an oxygen storage/release material and a perovskite oxide disposed in contact with the oxygen storage/release material and represented by the general formula LaxM11-xM2O3-?, where La is lanthanum, M1 is at least one element selected from the group consisting of barium (Ba), strontium (Sr) and calcium (Ca), M2 is at least one element selected from the group consisting of iron (Fe), cobalt (Co) and manganese (Mn), x satisfies 0<x?1, and ? satisfies 0???1; and a holding material that holds the first catalyst unit and the second catalyst unit in a mutually separated state.Type: ApplicationFiled: January 16, 2015Publication date: September 21, 2017Applicant: NISSAN MOTOR CO., LTD.Inventors: Junji ITO, Yasunari HANAKI, Tetsuro NAITO, Misaki AKAISHI
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Publication number: 20170266645Abstract: This invention relates to a hydrodesulfurization catalyst, a method for preparing the catalyst, and a method for the preparation of low sulfur gasoline fuel with minimal loss of RON. The catalyst particles include a group VIB metal and a support material having relatively high surface area, and optionally includes one or more group VIIIB metal. The method for preparing the catalyst allows for greater loading of the active metal species on the surface of the support material under aqueous reaction conditions.Type: ApplicationFiled: February 16, 2017Publication date: September 21, 2017Inventors: Ki-Hyouk Choi, Sameer Ali Al-Ghamdi, Ali H. Al-Shareef, Ali H. Al-Hamadah
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Publication number: 20170266646Abstract: One exemplary embodiment of the present disclosure can be a catalyst for catalytic reforming of naphtha. More specifically, the present disclosure relates to a reforming catalyst for the catalytic reforming of gasoline-range hydrocarbons that results in increased aromatics production. The catalyst can have a noble metal including one or more of platinum, palladium, rhodium, ruthenium, osmium, and iridium, one or more alkaline earth metals, and a support.Type: ApplicationFiled: June 1, 2017Publication date: September 21, 2017Inventors: Manuela Serban, Erik Holmgreen
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Publication number: 20170266647Abstract: In an embodiment, a process of making a catalyst can comprise contacting a zeolite with an aluminum solution comprising an aluminum compound at a pH of 2 to 6; calcining the zeolite to form the catalyst; wherein the catalyst comprises 0.1 to 5 wt % aluminum based on the total weight of the catalyst excluding any binder or extrusion aide. In an embodiment, a process of aromatizing methane can comprise aromatizing a feed comprising methane in the presence of the catalyst under aromatization conditions.Type: ApplicationFiled: September 2, 2015Publication date: September 21, 2017Inventors: Sami Muteib Almutairi, Labeeb A. Chaudhary, Majed Mohammed Mussa, Mayank Harishbhai Vyas
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Publication number: 20170266648Abstract: Methods of isotopic labeling are described herein. For example, a method of isotopically labeling an organic compound, in some embodiments, comprises providing a reaction mixture including the organic compound, an iron complex or a cobalt complex and a source of deuterium or tritium. The organic compound is labeled with deuterium or tritium in the presence of the iron complex or cobalt complex or derivative of the iron complex or cobalt complex.Type: ApplicationFiled: July 29, 2015Publication date: September 21, 2017Inventors: Paul CHIRIK, Renyuan YU
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Publication number: 20170266649Abstract: An oxidation catalyst may include hydrocarbon storage material. One implementation relates to a diesel oxidation catalyst that includes a catalyst having a front zone and a rear zone and a gradient of hydrocarbon storage material on the catalyst extending from the front zone to the rear zone. The gradient of hydrocarbon storage material, may comprise a linear gradient, a step gradient, a parabolic gradient, a logarithmic gradient, or other forms thereof.Type: ApplicationFiled: March 14, 2017Publication date: September 21, 2017Applicant: Cummins Emission Solutions Inc.Inventors: Shirish S. Punde, Arvind V. Harinath, Changsheng C. Su, Aravindh K. Kanakamedala
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Publication number: 20170266650Abstract: The present disclosure provides a visible light activated photocatalytic tile, comprising a porous ceramic tile; and a photocatalytic layer formed on one surface of the tile with a coating composition comprising an aqueous solvent and visible light activated photocatalytic particles.Type: ApplicationFiled: September 22, 2015Publication date: September 21, 2017Inventors: Joo-Hwan SEO, Dong-Il LEE, Hye-Youn JANG, Seong-Moon JUNG
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Publication number: 20170266651Abstract: Process for the manufacture of at least one alcohol and/or at least one ketone, which comprises a step during which at least one organic peroxide compound is put into contact with at least one catalyst responding to formula (I) CrNxOy Formula (I) in which x is a number varying from 0.10 to 1.00 and y is a number varying from 0.00 to 1.50, in order to produce the at least one alcohol and/or at least one ketone.Type: ApplicationFiled: November 20, 2015Publication date: September 21, 2017Inventors: Sandra CHOUZIER, Luis Fernando RASCON CRUZ, Bert WECKHUYSEN, Sergio MASTROIANNI
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Publication number: 20170266652Abstract: A non crosslinked, covalently crosslinked and/or ionically crosslinked polymer, having repeating units of the general formula (1) —K—R—??(1) In which K is a bond, oxygen, sulfur, the radical R is a divalent radical of an aromatic or heteroaromatic compound.Type: ApplicationFiled: May 30, 2017Publication date: September 21, 2017Inventor: Thomas Häring
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Publication number: 20170266653Abstract: Methods of concentrating beads in a droplet and/or loading beads on a fluidic device are provided, including among other things, a method of concentrating beads in a droplet, the method comprising: (a) providing a droplet actuator comprising: (i) an interior droplet operations volume; and (ii) a reservoir exterior to the interior volume; (iii) a droplet established in a liquid path extending from the reservoir into the interior volume; (b) providing magnetically responsive beads in the portion of the droplet which is in the reservoir; (c) magnetically attracting the magnetically responsive beads through the liquid path into the portion of the droplet which is in the interior volume; and (d) forming a droplet comprising one or more of the magnetically responsive beads in the interior volume.Type: ApplicationFiled: June 6, 2017Publication date: September 21, 2017Inventors: Michael G. POLLACK, Ramakrishna SISTA, Zhishan HUA, Vamsee K. PAMULA, Arjun SUDARSAN, Vijay SRINIVASAN, Prasanna THWAR, Alexander SHENDEROV, Dwayne ALLEN
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Publication number: 20170266654Abstract: A fluid analyzer manifold for facilitating flow of a fluid through at least one surface mounted component for analysis by a fluid analyzer. The exemplary fluid analyzer manifold can include an analysis chamber for connection with the fluid analyzer, a first flow channel having a first surface opening and a second flow channel having a second surface opening on the fluid analyzer manifold, and a mounting area on the fluid analyzer manifold. The mounting area can include the first and second surface openings of the first and second flow channels, and facilitates surface mounting the at least one surface mounted component to the fluid analyzer manifold.Type: ApplicationFiled: March 18, 2016Publication date: September 21, 2017Inventors: John Paul Sanroma, Mariah Inez Hake
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Publication number: 20170266655Abstract: Provided is a microparticle measurement device that can deliver a liquid that is used in the analysis of microparticles in a stable manner. The microparticle measurement device includes a plurality of first tank units to which a liquid is supplied from the outside, and which are respectively connected in parallel, and a bulb unit that is connected to the plurality of first tank units, and which switches to a state in which it is possible to deliver the liquid to a flow channel through which microparticles flow. According to this microparticle measurement device, in addition to performing liquid delivery from a portion of first tank units, in which the replenishment of liquid has been completed, to a flow channel, it is possible to supply liquid from the outside to first tank units other than the first tank units that are delivering liquid.Type: ApplicationFiled: June 6, 2017Publication date: September 21, 2017Inventor: Yosuke MURAKI
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Publication number: 20170266656Abstract: Provided is a cell capturing cartridge. According to an embodiment of the inventive concept, the cell capturing cartridge may include a substrate and structures provided on an upper surface of the substrate and constituting a plurality of rows that are parallel to a row direction. The structures in one row may be offset from the structures in the neighboring rows in the row direction. Each of the substrates may have a first side surface facing one side of the substrate and a second side surface disposed opposite to the first side surface and having a width greater than that of the first side surface.Type: ApplicationFiled: February 14, 2017Publication date: September 21, 2017Applicants: Electronics and Telecommunications Research Instit ute, GenoBio Corp.Inventors: Dae-Sik LEE, Jeong Won PARK, Moon Youn JUNG, Do Hyung KIM, Jae Ku LEE, Hun Seok LEE
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Publication number: 20170266657Abstract: Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.Type: ApplicationFiled: April 14, 2017Publication date: September 21, 2017Applicant: CUE INC.Inventors: Ayub Khattak, Clinton Sever, Paul Nelson, Ryan Cooper, Thomas Congdon, Justin Demartino, Raphael Shapiro, Mark Duncan
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Publication number: 20170266658Abstract: The present invention provides a method of collecting a liquid sample using a leak proof, air tight plastic container device. The method comprises placing the sample in the container device, the device comprised of a container, a lid, a lid groove containing a gasket therein which covers and tightens over the rim of the container, a lid flange, and a thin hook in the container containing a second gasket compressed by the lid flange when the lid is closed over the container; and sealing the sample in the container device by engaging the internal screw threads of the lid with the external screw threads of the container and rotating the lid until resistance to rotation is encountered. The method further comprises transporting the sample to a site for analysis, whereby no leakage of the liquid sample and no air seepage into or out of the container occur during transport.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Albert R. Bruno, Alex V. Strahan
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Publication number: 20170266659Abstract: The present invention provides integrated sample preparation systems and stabilized enzyme mixtures. In particular, the present invention provides microfluidic cards configured for processing a sample and generating DNA libraries that are suitable for use in sequencing methods (e.g., next generation sequencing methods) or other suitable nucleic acid analysis methods. The present invention also provides stabilized enzyme mixtures containing an enzyme (e.g., an enzyme used in whole genome amplification), BSA, and a sugar. Such enzyme mixtures may be lyophilized and stored at room temperature without significant loss of enzyme activity for months.Type: ApplicationFiled: March 30, 2017Publication date: September 21, 2017Inventors: Mark Eshoo, John Picuri
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Publication number: 20170266660Abstract: The technology described herein is directed to methods of cryopreservation, e.g., cryopreservation in a microfluidics format and methods of utilizing cells preserved by such methods.Type: ApplicationFiled: September 30, 2015Publication date: September 21, 2017Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Raymond Manohar ANCHAN, Sinan GUVEN, Utkan DEMIRCI, George Luther MUTTER
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Publication number: 20170266661Abstract: A separation assembly for separation of a fluid into first and second parts is disclosed. A container has a first end, a second end, and a sidewall extending therebetween defining an interior, the container defining a longitudinal axis between the first end and the second end. A separator body is disposed within the interior having a through-hole defined therethrough. The separator body includes a first part, and a second part interfaced with the first part, wherein the separator body is transitionable from a first position wherein the through-hole is provided in fluid-receiving alignment with the first end of the container, to a second position wherein the through-hole is provided substantially perpendicular to the longitudinal axis of the container. In the first position, a through-axis of the through-hole of the separator body is in a plane that is not parallel with a plane containing the longitudinal axis of the container.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Robert J. Losada, Arun U. Nair
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Publication number: 20170266662Abstract: A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float having a passageway extending between first and second ends thereof with a pierceable head enclosing the first end of the float, a ballast longitudinally moveable with respect to the float, and a bellows extending between a portion of the float and a portion of the ballast. The bellows is adapted for deformation upon longitudinal movement of the float and the ballast, with the bellows isolated from the pierceable head. The float has a first density and the ballast has a second density greater than the first density. The bellows is structured for sealing engagement with a cylindrical wall of a tube, and the pierceable head is structured for application of a puncture tip therethrough. The separation device is suitable for use with a standard medical collection tube.Type: ApplicationFiled: June 7, 2017Publication date: September 21, 2017Inventors: Shenika E. Felix, Jamieson W. Crawford, Christopher A. Battles, Jes Tougaard Gram
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Publication number: 20170266663Abstract: An assembly for processing a sample is provided. The assembly comprises a first body having a plurality of spaced-apart conduits and a second body having a plurality of chambers wherein each conduit is fluidically connected to a separate chamber. The assembly forms a plurality of liquid flow paths, each flow path comprising a conduit and a chamber. An analyte capture element is detachably attached to a conduit and is in fluidic communication with the liquid flow path of the conduit. Optionally, the assembly further may comprise a third body comprising a plurality of reservoirs. The assembly can be used to process a liquid sample for detecting an analyte.Type: ApplicationFiled: June 2, 2017Publication date: September 21, 2017Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: JON A. KIRSCHHOFFER, ANDREW H. TILSTRA, WENSHENG XIA
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Publication number: 20170266664Abstract: A device for sealing a reagent container storing and providing liquids, in particular in an analyzer system. The invention also relates to a reagent container using such device for sealing, a cartridge for holding such reagent container, and a method for removing a liquid from such reagent container. The instant invention provides a device for sealing a reagent container comprising an annular member configured to be inserted into the reagent container, wherein the annular member is configured to being movably coupled to the reagent container relative to its longitudinal center axis; an opening passing from a top end of the annular member to a bottom end of the annular member; and a sealing element arranged between the top end and the bottom end of the annular member for sealing the opening.Type: ApplicationFiled: March 21, 2017Publication date: September 21, 2017Inventors: Waldemar Lukhaub, Martin Trump, Sara Zimmermann
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Publication number: 20170266665Abstract: Devices, systems, and methods for separating cells or vesicles using a thermo-acoustophoretic approach are provided. A microfluidic device can be used for stiffness-based separation of cells or vesicles that otherwise have the same or approximately the same size, shape, and charge, where at least some of the membranes or vesicles have different compositions. The separation can be done by tuning the temperature of the cells or vesicles.Type: ApplicationFiled: March 20, 2017Publication date: September 21, 2017Applicant: The Florida International University Board of TrusteesInventors: Bilal El-Zahab, Ata Dolatmoradi
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Publication number: 20170266666Abstract: The embodiments disclosed herein relate to unitized reagent strips for holding and transporting reagents and materials used in automated sample preparation and/or processing for biological and or chemical assays.Type: ApplicationFiled: October 27, 2016Publication date: September 21, 2017Inventors: Ammon David Lentz, Richard St. Pierre, Dwight Livingston, Adam Bruce Steel
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Publication number: 20170266667Abstract: The invention concerns a thermal cycler and a microtiter plate. The cycler comprises a sample holder having a first surface and a surface and means for automated, controlled heating and cooling of the sample holder. The first surface of the sample holder is designed to hold a plurality of samples arrayed in a grid having a predefined pitch. The number of samples in one dimension is an exact match of the SBS plate standards for that sample pitch and in another dimension corresponds to a fraction of the number of samples in a second dimension of an SBS microtiter standard plate. According to the invention, the sample holder is shaped such that the area of the second surface is larger than the area of the first surface. By means of the invention, the thermal ramping speeds of the cycler can be significantly increased.Type: ApplicationFiled: March 8, 2017Publication date: September 21, 2017Inventors: Michael J. Mortillaro, David A. Cohen
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Publication number: 20170266668Abstract: The instant disclosure provides nucleic acid amplification systems and multi-reaction analysis systems useful in the efficient processing of samples, including clinical samples. Integrated systems that include nucleic acid amplification devices functionally combined with multi-reaction analysis systems are also included. Also provided are methods for monitoring multiple concurrent nucleic acid amplification reactions that include the use of devices and systems described herein.Type: ApplicationFiled: March 15, 2017Publication date: September 21, 2017Inventors: Sonal Sadaria Nana, Eric B. Shain, Michael S. Hazell, Eric D. Yeaton, Michael Giraud, Matthew J. Hayes, Timothy J. Patno, Ali Attarwalla, Dean Khan
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Publication number: 20170266669Abstract: A pick system includes a holder and a pick assembly. The holder includes a first end, a second end, and a bore extending between the first end and the second end and defining a longitudinal axis. The surface of the bore may be tapered so that the diameter of the bore proximate the first end is greater than the diameter of the bore proximate the second end. The pick assembly includes a shaft. The shaft is received within the bore of the holder along the longitudinal axis, and the shaft may be tapered to mate with the bore.Type: ApplicationFiled: June 2, 2017Publication date: September 21, 2017Inventors: Brett W. Rhea, Charles M. Anderson, JR., Joshua A. Fuhr, Charles W. Watson, William Harney, Jarrod Elliott
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Publication number: 20170266670Abstract: Disclosed are magnetic nanoparticles and methods of using magnetic nanoparticles for selectively removing biologics, small molecules, analytes, ions, or other molecules of interest from liquids.Type: ApplicationFiled: April 5, 2017Publication date: September 21, 2017Inventor: Adam L. STEIN