Abstract: In a photoacoustic measurement apparatus and a photoacoustic measurement system, it is possible to generate blood flow information using a photoacoustic image without requiring a separate tourniquet. A light source emits measurement light. A probe detects a photoacoustic wave generated in a subject after measurement light is emitted to the subject in each of the avascularized condition in which the subject is avascularized and the non-avascularized condition in which the subject is not avascularized. Photoacoustic image generation unit generates a photoacoustic image based on the detection signal of the photoacoustic wave. Blood flow information generation unit generates blood flow information based on the signal value of a photoacoustic image in a region of interest set in the photoacoustic image. The avascularization of the subject is performed by pressing the probe against the subject.

Abstract: A photoacoustic measurement probe and a probe unit capable of preventing generation of artifacts in a photoacoustic measurement apparatus are obtained. In a photoacoustic measurement probe having a light emitting unit that emits measurement light toward a subject, an acoustic wave detection element that detects an acoustic wave emitted from a portion of the subject that has received the measurement light, and a housing which has a surface facing the subject at the time of use and in which the light emitting unit and the acoustic wave detection element are housed, at least one slit that is opened to the housing surface and that extends from the housing surface toward the inside of the housing is provided between the light emitting unit and the acoustic wave detection element.

Abstract: A system for determining a clinically relevant temperature differential between a predetermined area of interest on the body surface of a mammal and a control area on the body surface of said mammal, said system comprising: a visual and thermal image capturing device, said image capturing device comprising: a housing, a means for capturing a digital visual image within said housing; and a means for capturing a digital thermal image within said housing; a display apparatus, said display apparatus comprising means for showing said captured visual image and said captured thermal image; and a computing apparatus, said computing apparatus operatively connected to said image capturing device and to said display apparatus, said computing apparatus comprising: a means for selecting a control area on the surface of the skin; a means for determining an temperature of said control area; a means for selecting an area of clinical interest within said visual image; a means for calculating plane geometric features of said s

Abstract: A system for determining a clinically relevant temperature differential between a predetermined area of interest on the body surface of a mammal and a control area on the body surface of said mammal, said system comprising: a visual and thermal image capturing device, said image capturing device comprising: a housing, a means for capturing a digital visual image within said housing; and a means for capturing a digital thermal image within said housing; a display apparatus, said display apparatus comprising means for showing said captured visual image and said captured thermal image; and a computing apparatus, said computing apparatus operatively connected to said image capturing device and to said display apparatus, said computing apparatus comprising: a means for selecting a control area on the surface of the skin; a means for determining an temperature of said control area; a means for selecting an area of clinical interest within said visual image; a means for calculating plane geometric features of said s

Abstract: A method of using long wave infrared thermography (LWIT) to quantify the characteristic temperature changes associated with infected wounds to accurately confirm the existence of or absence of infection.

Abstract: An intelligent wearable device and a detection method of biometric information of the intelligent wearable device. The intelligent wearable device includes: a wearable device body; and a light source, a first photoelectric detection module, a second photoelectric detection module and a processing module disposed on the wearable device body. The light source is configured to emit light towards a human-body wearing part; the light includes transmitted light that passes through the human-body wearing part and reflected light reflected by the human-body wearing part; the first photoelectric detection module is configured to detect the transmitted light; the second photoelectric detection module is configured to detect the reflected light; and the processing module is configured to determine a first type of biometric information of a human body according to the transmitted light and determine a second type of biometric information of the human body according to the reflected light.

Abstract: Methods, apparatus and systems for characterizing changes in at least one physical properly of soft tissue. A series of acoustic pulses is generated and directed into the soft tissue such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the tissue. Waves reflected off the tissue, or a flexible member that moves with the tissue, are received and measured to estimate at least one characteristic of the physical displacement induced thereby. Repetition of the generating, receiving and estimating steps provides characterization of the at least one physical property over time. Methods, apparatus and systems for characterizing at least one physical property or blood, by generating a series of acoustic pulses and directing the series of pulses into the blood such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the blood.

Abstract: A vaginal blood-inspecting apparatus, including: a cloth, including a sheet, a rod, such that the first end thereof is for being wrapped by the sheet of the cloth, and the second end thereof is for pushing thereon from outside the vagina, for inserting the cloth thereinto, and a hollow cylinder, for covering a portion of the rod and of the cloth, thereby the hollow cylinder maintains the wrapping of the sheet on the rod, thereby sliding of the hollow cylinder towards the second end of the rod removes the hollow cylinder from the rod without removing the sheet from the rod, thereby exposing the cloth to the internal wall of the vagina.

Abstract: Ambulatory monitoring of human health is provided by a multi-component multi-sensor wireless wearable biosignal acquisition system comprising a torso device and a peripheral device communicating wirelessly, and a mobile phone for receiving collected data and uploading it over cellular network or WiFi to a remote computer for multivariate analysis. Biosignals include EKG and PPG, from which a determination of pulse transit time can be made.

Abstract: A method of quantifying crucial limb ischemia, the method including the steps of: acquiring temperature data over time of a wound using LWIT; creating a database of the acquired temperature data; comparing the data of the created database to known Heterogeneity Indices; and evaluating the comparisons to assess wound healing.

Abstract: A computer-implemented method of visualizing blood flow through a patient using magnetic resonance imaging (MRI) includes receiving an image of the portal venous system of the patient's liver at a full field of view. A reduced field of view is defined which encompasses the portal venous system of the patient's liver and excludes extraneous anatomy in the full field of view. A navigator area is defined in the full field of view and outside of the reduced field of view. Transmit channels are used to selectively excite the reduced field of view and the navigator area throughout a cardiac cycle of the patient. Measurement data is acquired in response to the selective excitation. The acquired data is used to generate time-resolved 3D datasets. Additionally, a 3D visualization of blood flow though the portal venous system is generated based on the time-resolved 3D datasets.

Abstract: A blood pressure cuff may comprise an alignment component, a sleeve, and a tapered inflatable bladder disposed within the sleeve. The tapered inflatable bladder may have a width that increases as the distance from the alignment component increases, and the tapered inflatable bladder and the alignment component may be configured to position the blood pressure cuff around a limb having a blood vessel and a circumference, such that at a position coincident with the blood vessel, the width of the tapered inflatable bladder is about 40% of the circumference of the limb. A method of using such a blood pressure cuff may comprise placing the alignment component at the position coincident with the blood vessel of the limb, wrapping the cuff around the limb such that the width of the tapered inflatable bladder overlaying the blood vessel is about 40% of the circumference of the limb, and inflating the bladder.

Abstract: A photoelectric sensor can include: a lighting element configured to generate a first optical signal, where a second optical signal is generated by reflection of the first optical signal when emitting an object; a driving circuit configured to drive the lighting element; a photoelectric conversion circuit configured to generate a first optical current in accordance with the second optical signal; and a programmable current amplifier circuit configured to sample and hold the first optical current when the lighting element is in operation, and to generate a second optical current when the lighting element is out of operation in one detection period, where the second optical current lasts for at least one working period in the detection period, and where the second optical current represents the first optical current.

Abstract: Methods for heart rate measurement based on pulse oximetry are provided that can tolerate some degree of relative displacement of a photoplethysmograph (PPG) heart rate monitor device. In some methods, artifact compensation based on a reference signal is performed on the PPG signal data to remove artifacts in the signal that may be caused, for example, by changes in ambient light and/or motion of a person wearing the monitor device. The reference signal used for artifact compensation may be generated using an LED of a complementary wavelength to that of the LED used to generate the PPG signal, or by driving an LED at a lower current than the current applied to generate the PPG signal.

Abstract: A system for monitoring a subject for an arrhythmia includes an external monitoring device (EMD) configured to be disposed outside of a subject's body. The EMD includes a first communication component configured to receive, from a medical device, a first physiological parameter signal and an indication of a detected trigger event associated with a first portion of the first physiological parameter signal. The trigger event is indicative of a potential arrhythmia. The EMD also includes an analysis component configured to (1) identify a second portion of the first physiological parameter signal, where the second portion satisfies a discard criterion, (2) discard the second portion, and (3) perform an arrhythmia confirmation evaluation using a third portion of the first physiological parameter signal.

Abstract: Embodiments of the present application provide a headphone with a biological feature detection function, an interaction system and a biological feature detection method. The headphone includes: a loudspeaker, a microphone, a biological feature detection module, a mode switching module, a first communication module, a control module and a power management module. The control module is configured to detect and determine whether an instruction is received from the smart terminal, and control, according to the instruction received from the smart terminal, the biological feature detection module, the mode switching module, the power management module and the first communication module to work, and further configured to parse the biological feature from the biological feature detection module under control of the instruction received from the smart terminal, and transmit the parsed biological feature to the smart terminal via the first communication module.

Abstract: The present invention relates to a method of diagnosing whether a subject with no known history of atrial fibrillation is suffering from atrial fibrillation, or not, said method comprising the steps of a) determining the amount of a BNP-type peptide in a sample of said subject; b) comparing the amount the BNP-type peptide to a reference, and c) assessing intermittent ECG recordings obtained from said subject over a period of at least one week by using a handheld ECG device.

Abstract: An electrically conductive material including a base and a conductive polymer applied uniformly to the base's surface and having a reduced resistance value. Specifically, the electrically conductive material includes PEDOT-pTS, serving as a conductive polymer, applied to the base comprised mostly of silk. Also the enclosed provide a method for producing the electrically conductive material, and a bioelectrode including it.

Abstract: A biological recording device used to monitor biological electrical activity and a method of recording neural signals. In a preferred embodiment, the biological recording device is a neural probe. The biological recording device includes a probe body with a probe shank and a recording platform that uses a delta (?) modulator and a delta sigma analog to digital converter (?? ADC). The ? modulator and the ?? ADC form a ?-?? analog front end (AFE) architecture for processing biological electrical activity. A large dynamic range (DR) of neural signals, including local field potentials (LFPs) and action potentials (APs) for example, can be compressed and subsequently reconstructed.

Abstract: A method and device for biomedical recording of biomedical spike signals is provided. The method includes extracting and aligning possible biomedical spike signals from received signals and, thereafter, performing spike detection by determining whether the possible biomedical spike signals are actual spike signals. The biomedical spike signals are preferably selected from electrocardiography (ECG), electroencephalography (EEG) and neural signals.

Abstract: A method of generating a cardiac electrophysiology map includes receiving a reference biological signal and an electrical signal indicative of electrical activity at a location on a patient's heart. Using a graphical user interface, a practitioner designates at least two trigger point icons, one upward-pointing and one downward-pointing, on a graphical representation of the reference biological signal (e.g., a waveform). By pairing one upward-pointing icon with one downward-pointing icon, a plurality of triggering criteria are defined. Electrophysiology data points are captured and/or added to the electrophysiology map when the triggering criteria are satisfied.

Abstract: Systems and methods are described for detecting and characterizing seizures or seizure-related events. The methods herein may include determining magnitude and/or scaled magnitude data for each of at least one high and low frequency group of signals. Based on the determined magnitudes and/or scaled magnitude data, seizures or seizure-related events may be characterized.

Abstract: A basket style electrical mapping catheter includes an elongated body with a proximal end and a distal end, where the proximal end has a user interface for controlling a basket-shaped electrode assembly that extends from the distal end of the elongated body. The basket-shaped electrode assembly includes a plurality of flexible splines supporting measurement electrodes configured to contact an electrically active substrate, and an expander spline disposed along a central axis of the basket-shaped catheter assembly supported a reference electrode. The orientation of the measurement electrodes relative to the reference electrode allows for electrical mapping to be conducted with greater sensitivity and specificity in order to more accurately detected diseased or damaged substrate.

Abstract: The invention provides decision tree based systems and methods for estimating the risk of acute coronary syndrome (ACS) in subjects suspect of having ACS. In particular, systems and methods are provided that employ additive decision tree based algorithms to process a subject's initial cardiac troponin I or T (cTnI or cTnT) concentration, a subject's cTnI or cTnT rate of change, and at least one of the following: the subject's age, the subject's gender, the subject's ECG value, the subject's hematology parameter value, to generate an estimate risk of ACS. Such risk stratification allows, for example, patients to be ruled in or rule out with regard to needing urgent treatment.

Abstract: A cardiac rhythm management system includes at least one sensing component configured to obtain a first physiological parameter signal, an indication of a cardiac response to a stimulation therapy, and temporal information corresponding to the first physiological parameter signal and the cardiac response; and at least one processor configured to: receive the first physiological parameter signal, the indication of the cardiac response, and the temporal information; and to classify the cardiac response into a first cardiac response class to generate a classified cardiac response. The at least one processor also is configured to determine a correlation, based on the temporal information, between the first physiological parameter signal and the classified cardiac response.

Abstract: A method of managing pain using neurophysiological data acquired from the brain of a subject is disclosed. The method comprises: identifying activity-related features in the data; parceling the data according to the activity-related features to define a plurality of capsules, each representing a spatiotemporal activity region in the brain; comparing at least some of the defined capsules to at least one reference capsule; and assessing the likelihood that the subject is experiencing pain responsively to the comparison.

Abstract: Various embodiments of the present disclosure relate to an electronic device for measuring biometric information and a device for charging the electronic device. The electronic device may include a housing having a top surface and a bottom surface, a first electrode disposed on the top surface of the housing, the first electrode electrically isolated from rest of the top surface, a second electrode disposed on the bottom surface of the housing and contacting a user's body when the electronic device is worn by the user, a sensor module electrically coupled to the first electrode and the second electrode, a processor electrically coupled to the sensor module, a display module electrically coupled to the processor; and a memory electrically coupled to the processor.

Abstract: A method and system for extracting important signal information is disclosed. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.

Abstract: A method is described for determining biological tissue type based on a complex impedance spectra obtained from a probe with a conducting part adjacent a tissue region of interest, wherein the impedance spectra includes data from a number of frequencies. The method may include: obtaining, from the complex impedance spectra, a first data set representative of impedance modulus values, or equivalent admittance values, at one or more frequencies, obtaining, from the complex impedance spectra, a second data set representative of impedance phase angle values, or equivalent admittance values, at one or more different frequencies, applying a first discrimination criterion to the first data set, applying a second discrimination criterion to the second data set, and thereby determining if the tissue region of interest is a tissue type characterised by the discrimination criteria.

Abstract: An apparatus and method for imaging a tissue. The method includes transmitting a first microwave frequency signal to and receiving a first total signal from the tissue at a first position. A second microwave frequency signal is transmitted to and a second total signal received from the tissue at a second position. The first total signal is calibrated with respect to the second total signal and an image is constructed from the calibrated signal.

Abstract: Various embodiments are described herein for a device, system, and method for identifying a location of an ingestible device within a gastrointestinal tract of a body. In some embodiments, the ingestible device includes a sensing unit with an axial optical sensing sub-unit located proximal to at least one end of the device, and a radial optical sensing sub-unit located proximal to a radial wall of the device, and may autonomously identify a location within the gastrointestinal tract. In some embodiments, the ingestible device includes optical illumination sources and detectors that operate at a plurality of different wavelengths, and may discern regions of a gastrointestinal tract by using the reflection properties of organ tissue and occasional particulates. In some embodiments, the ingestible device may sample fluid or release medicament based on a detected device location.

Abstract: Embodiments of the present disclosure provide methods, apparatuses, devices and systems for measuring vital signs in human and animals by interrogating electromagnetic signals reflected from tissues in a human or animal subject. Probes may transmit radio frequency electromagnetic waves into a living body and generate signals responsively to the waves that are scattered from within the body. Such embodiments may be suitable for wearable devices as well as for use by medical practitioners.

Abstract: A breathing system includes a facepiece and a regulator to deliver breathing gas to the facepiece. The regulator includes a sensor system including at least one sensor responsive to respiration of a user. The breathing system further includes a processor system in operative connection with the at least one sensor, a memory system in operative connection with the processor system and at least one algorithm stored in the memory system and executable by the processor system. The at least one algorithm is adapted, configured or programmed to determine at least one of a rate of respiration and a respiration volume from data from the at least one sensor. The algorithm is further adapted, configured or programmed to relate at least one of the rate of respiration and the respiration volume to a physiological state of the user.

Abstract: There is provided herein methods, apparatus and systems for evaluating carbon dioxide (CO2) concentration in a subject's breath, for example in subjects ventilated with High Frequency Ventilation (HFV), the method includes inserting to a trachea of a subject an endotrachial tube (ETT), sampling breath from an area in the trachea located in proximity to a distal end of the endotrachial tube (ETT) and evaluating one or more CO2 related parameters of the sampled breath.

Abstract: On a wearable and Internet of Things (IOT) device that is proximate to a user equipment, a method to detect reflective zones of the wearable device may include, in response to a preset criterion, obtaining a characteristic of the left foot pressure points, obtaining a characteristic of the right foot pressure points, obtaining a pressure sensor on the wearable device, obtaining a position sensor on the wearable device, obtaining a force sensor on the wearable device, obtaining kinetic energy movement from the wearable device, and obtaining the radio characteristic of the wearable device. The method may also include transmitting the left foot pressure points characteristic, the right foot pressure points characteristic, the pressure sensor on the wearable device, the position sensor on the wearable device, the force sensor on the wearable device, the kinetic energy movement from the wearable device, and the radio characteristic to a user equipment.

Abstract: Methods, systems, and computer readable medium are disclosed herein comprising detecting a first tension; detecting a second tension; determining a difference between the first tension and the second tension; and estimating a volume change based at least in part on the determined difference.

Abstract: Disclosed are a system and a method for rehabilitation exercise of hands. The system and the method help a device sense movements of the hands more accurately. The device for rehabilitation exercise of the hands comprising multiple sense parts that are located on each part of a user's hand, and configured to sense movements of the each part; and communication part configured to send movement data sensed by the multiple sense parts to an output device.

Abstract: A method for assessing ergonomics of a human user in an environment is disclosed. The method includes generating a visual skeletal signal by using a visual sensor. The method further includes determining a first posture sample based on the skeletal signal, by using an electronic controller. The posture sample includes skeletal information including one or both of joint information and positioning information. The method further includes comparing the posture sample with an ergonomically ideal posture sample and determining an ergonomic report based on the comparing of the posture sample and the ergonomically ideal posture sample. The method further includes providing the ergonomic report via an output device.

Abstract: An apparatus and method for recognizing a gait motion by detecting a landing point in time of a foot of a user based on sensed acceleration information, inferring a gait motion based on right and left hip joint angle information of the user sensed at the detected landing point in time of the foot of the user, and detecting a landing leg between both legs of the user based on the inferred gait motion may be provided.

Abstract: In an example embodiment, this disclosure provides a computer system that includes a processor configured to compute, based on test performance data of a user, at least one performance variable characterizing balance and postural stability, and at least one performance variable characterizing vestibulo-ocular reflex (VOR). For each performance variable, processor can compute a respective score based on the respective performance variable and based on a set of performance metrics. The at least one computed score can be output via an output device.

Abstract: A comfort band is configured to be worn between an electronic surveillance bracelet and a leg of a wearer. The comfort band includes a tubular elastic element adapted to retain the comfort band on the leg of the wearer. The comfort band further includes a cushion provided along a lower edge of the elastic element so that the cushion is located towards the foot of the wearer. The cushion extends outwardly from the elastic element and is arranged so as to form an abutment for an end face of the electronic surveillance bracelet.

Abstract: A method for monitoring an occupant of an occupant support comprises 1) establishing a lateral position history of the occupant, which history includes an assessment of how frequently the occupant's head undergoes a lateral transition on a head support, 2) establishing a vertical position history of the occupant which accounts for how frequently the weight of the occupant's head is applied to and removed from the head support, and 3) if the lateral position history indicates sustained repetitive lateral movement or the vertical history indicates other than sustained presence of the occupant's head on the head support, reporting that the occupant is in a state other than an acceptable state.

Abstract: We describe a user exercise-tolerance measuring pulse oximeter system, for determining the exercise tolerance or capacity of a user undergoing exercise, the system comprising: a wireless fingerband comprising an optical sensor to provide an oxygen saturation signal, a chargeable power supply, and a wireless transmitter/receiver; a motion detector to provide a user motion signal; and a signal processor coupled to said wireless fingerband to data from said optical sensor, and coupled to said motion detector; wherein said signal processor is configured to: process a combination of said oxygen saturation signal and said user motion signal to determine exercise tolerance data, wherein said exercise tolerance data is dependent upon said oxygen saturation signal and a level of exertion of said user determined from said user motion signal; and to time or count a period or quantity of user motion or movements, during said exercise, identified by said motion detector, to determine said level of exertion; to measure a d

Abstract: A device for measuring an angular difference in a range of motion of the arms of a patient comprises a gripping bar, a housing, and an angle-determining assembly comprising a weighted needle and a compass. When the patient raises her arms to their unassisted physiological limits, the device indicates an angle that represents the angular difference in the range of motion between the arms of the patient.

Abstract: Systems for studying motion are provided. A computing device [10] has a processor [20], an accelerometer [11], a gyroscope [12], a magnetometer [13] and storage/computer readable media [30] in communication with one another. The computing device [10] can sense, classify, qualify and/or quantify real-time motion data of a moving target against classified initial motion data in a motion library [32]. Motion data is processed as particularized units of motion. The computing device [10] may use machine learning algorithms for “training” and “learning.” The computing device [10] can be used in many industries, including the fitness industry, where computing device [10] can be used with wearable technology.

Abstract: The present disclosure describes systems, apparatus, and methods for collecting biometric data from a patient. In some cases, this biometric data can be collected during the course of an emergency encounter using a medical device. The medical device can also perform other functions, such as monitor patient vital signs, receive and record notes and textual information, communicate with other devices, and/or deliver a therapeutic treatment. The medical device can also be configured to record and/or maintain a patient record, and to embed the patient biometric data into the patient record for use in later confirming and/or determining an identity of the patient. Some embodiments can also collect biometric data relating to one or more caregivers of the patient, and to embed the caregiver biometric data into the patient record. This caregiver biometric data can be used to confirm and/or identify one or more caregivers in a patient record.

Abstract: The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.

Abstract: A system, for the transcutaneous measurement of a substance concentration, preferably alcohol, in blood, includes a light source (1); a detector device (15); an optical device (7, 7?), with an inlet (5), an outlet (49) and an exit opening (35); and a contact surface element (37) with a contact surface (41). Measuring radiation emitted by the light source (1) reaches the inlet (5) and exits the exit opening (35), to the contact surface (41). The optical device (7, 7?) focuses measuring radiation at a measuring point (39) at a predefined distance from the contact surface (41). The optical device (7, 7?) is configured such that scattered radiation generated in the measuring point (39) and entering into the exit opening (35) is focused at an outlet point (19) at the outlet (49). The detector device (15) is arranged to detect the scattered radiation focused at the outlet point (19).

Abstract: A device and a method to measure the concentrations of oxygenated and deoxygenated hemoglobin in tissue around a tumor via near-infrared (NIR) spectroscopy with a photonic mixer device (PMD) is described.

Abstract: A body-mountable light sensing device includes a photodiode configured to receive light from a portion of subsurface vasculature and electronics configured to operate the photodiode to measure the received light. The electronics include a photodiode voltage source configured to reverse bias the photodiode, a current mirror, and a sigma-delta modulator configured to generate a digital output related to the received light and having a high resolution while using low power. The digital output could be used to determine a pulse rate or other properties of blood in the portion of subsurface vasculature by detecting absorption of ambient light by blood in the portion of subsurface vasculature. Components of the body-mountable device could be embedded in a polymeric material configured for mounting to a surface of an eye. The digital output and/or related information could be wirelessly communicated by the body-mountable device.