Abstract: Provided herein are methods for the detection of genetic mutations associated with cancer, particularly in the KIT gene.

Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.

Abstract: Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence of L. pnuemophila in samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA.

Abstract: The present invention features rapid and accurate methods for detecting Salmonella (e.g., in a food product, environmental sample, biological sample or other material).

Abstract: The invention described herein provides for methods and systems for determining, selecting, and/or treating diseases and conditions caused by or associated with high quantities of methanogens in a subject, or diseases and conditions caused by or associated with low quantities of methanogens in a subject. In various embodiments, a therapy to inhibit the growth of methanogens or to promote the growth of methanogens are selected and/or administered to a subject in need thereof.

Abstract: Certain aspects of this disclosure relate to a method that comprises contacting a mammalian cell with a glucocorticoid receptor ligand and a myostatin receptor ligand, thereby activating the glucocorticoid receptor and said myostatin receptor. A screening assay employing the same is also provided.

Abstract: This invention relates to the production of chemicals by fermentation with a microorganism in which the fermentation medium contains the sugar sucrose. As a specific example, succinic acid is produced from a sucrose-containing renewable feedstock through fermentation using a biocatalyst. Examples of such a biocatalyst include microorganisms that have been enhanced in their ability to utilize sucrose as a carbon and energy source. The biocatalysts of the present invention are derived from the genetic manipulation of parental strains that were originally constructed with the goal to produce one or more chemicals (for example succinic acid and/or a salt of succinic acid) at a commercial scale using feedstocks other than sucrose. The genetic manipulations of the present invention involve the introduction of exogenous genes involved in the transport and metabolism of sucrose into the parental strains.

Abstract: A sugar composition comprising at least 40% dissolved solids in an aqueous solution having a viscosity at least 10% lower than a 42 DE (Dextrose Equivalents) reference solution with a same dissolved solids concentration at a given temperature. Another sugar composition comprising at least 30% glucose relative to total sugars, at least 10% mannose relative to total sugars, at least 5% xylose relative to total sugars, and less than 0.25% ash. Another sugar composition comprising at least 30% glucose relative to total sugars at least 10% mannose relative to total sugars, at least 5% xylose relative to total sugars, and at least 2% total furfurals.

Abstract: An apparatus for processing the skin side of a tubular fur, including a mandrel on which the tubular fur can be drawn from a first part of the mandrel towards a second part of the mandrel, one or more scraper units, each scraping unit having at least one scraper means configured for scraping the skin side when the fur is arranged on the mandrel, and a cover including a compartment and an outlet, where the cover encloses a part of the mandrel and at least one of the scraper means in the compartment during operation, where the outlet is arranged in a bottom part of the cover, and where the cover has walls with inner surfaces configured for leading material removed from the skin side by means of the scraper means towards the bottom part.

Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with an aqueous treatment formulation and a solid particulate material in a sealed apparatus, wherein the aqueous treatment formulation comprises at least one colorant. There is also disclosed an animal substrate obtained by the method and finished leather goods obtained by the method.

Abstract: The present invention provides a sub-zero treatment device capable of uniformly cooling a cooling target object and reducing the amount of liquid refrigerant used for cooling the cooling target object. The sub-zero treatment device has an exhaust member extending from a through-hole provided in a cooling tank constituting a cooling target object mounting chamber through to the interior of the cooling target object mounting chamber, and having an exhaust port, wherein the exhaust port is disposed in an exhaust port positioning space, which is the space located in the upper half of the cooling target object mounting chamber and having a width in the transverse direction that is equal to the maximum width in the transverse direction of the suction port.

Abstract: The present invention provides a rolled steel sheet, for press hardening, for which the chemical composition includes, with contents expressed by weight, 0.24%?C?0.38%, 0.40%?Mn?3%, 0.10%?Si?0.70%, 0.015%?Al?0.070%, 0%?Cr?2%, 0.25%?Ni?2%, 0.015%?Ti?0.10%, 0%?Nb?0.060%, 0.0005%?B?0.0040%, 0.003%?N?0.010%, 0.0001%?S?0.005%, 0.0001%?P?0.025%, it being understood that the titanium and nitrogen content satisfy: Ti/N>3.42, and that the carbon, manganese, chromium and silicon content satisfy: 2.6 ? C + Mn 5.3 + Cr 13 + Si 15 ? 1.1 ? % , with the chemical composition optionally including one or more of the following elements: 0.05%?Mo?0.65%, 0.001%?W?0.30%, 0.0005%?Ca?0.005%, with the remainder made up of iron and inevitable impurities coming from preparation.

Abstract: Provided are: a boron-added high strength steel for bolt excellent in delayed fracture resistance even having a tensile strength of 1100 MPa or more without addition of large amounts of expensive alloy elements such as Cr and Mo: and a high strength bolt made from the boron-added high strength steel for bolt. The high strength steel for bolt contains C of 0.23% to less than 0.40%, Si of 0.23% to 1.50%, Mn of 0.30% to 1.45%, P of 0.03% or less (excluding 0%), S of 0.03% or less (excluding 0%), Cr of 0.05% to 1.5%, V of 0.02% to 0.30%, Ti of 0.02% to 0.1%, B of 0.0003% to 0.0050%, Al of 0.01% to 0.10%, and N of 0.002% to 0.010%, with the remainder being iron and inevitable impurities. The steel has a ratio ([Si]/[C]) of the Si content [Si] to the C content [C] of 1.0 or more and has a ferrite-pearlite mixed microstructure.

Abstract: A beryllium-free high-strength copper alloy includes, about 10-30 vol % of L12-(Ni,Cu)3(Al,Sn), and substantially excludes cellular discontinuous precipitation around grain boundaries. The alloy may include at least one component selected from the group consisting of: Ag, Cr, Mn, Nb, Ti, and V, and the balance Cu.

Abstract: A copper alloy containing Ni: 1.5%-3.6% and Si: 0.3%-1.0% in terms of mass percent with the remainder consisting of copper and unavoidable impurities, wherein: the average crystal grain size of the crystal grains in the copper alloy is 5 to 30 ?m; the area ratio of the crystal grains having crystal grain sizes not less than twice the average crystal grain size is not less than 3%; and the ratio of the area of cube orientation grains to the area of the crystal grains having crystal grain sizes not less than twice the average crystal grain size is not less than 50%.

Abstract: In an aspect, a negative electrode for a lithium secondary battery and a method of manufacturing the same is provided. The negative electrode for the lithium secondary battery includes a negative active material layer.

Abstract: The disclosure is directed to a method of forming high-aspect-ratio metallic glass articles that are substantially free of defects and cosmetic flaws by means of rapid capacitive discharge forming. Metallic glass alloys that are stable against crystallization for at least 100 ms at temperatures where the viscosity is in the range of 100 to 104 Pa-s are considered as suitable for forming such high-aspect-ratio articles.

Abstract: The present disclosure relates generally to a fixture for use in applying a coating to a multiple vane nozzle for use in a turbomachine. The fixture includes first and second masks that are applied to opposite sides of the nozzle to mimic the geometry and spacing of the vanes of the nozzle.

Abstract: Provided is an equipment system for producing a piercing-rolling plug to be used for producing a seamless steel tube/pipe, which includes a shotblasting device for applying shotblasting on a surface of the plug, and an arc-spraying device for performing arc-spraying of iron wires on a surface of a base metal of the plug to which the shotblasting is applied, so as to form a film containing oxide and Fe thereon. The arc-spraying device includes plural spraying booths each of which separately forms part of the film in turn in each of sections into which the surface of the base metal of the plug is divided along an axial direction of the plug. The production efficiency of the plug can therefore be maintained at a high level, and steady enhancement of the durability life of the plug can be realized during the piercing-rolling.

Abstract: The present invention relates to a slip for producing an aluminum diffusion layer which comprises an Al-containing powder and an Si-containing powder and a binder, the slurry further comprising an Al-containing powder the powder particles of which are coated with Si. The invention further relates to a process for producing an aluminum diffusion layer, comprising the following steps: providing a slurry according to any one of the preceding claims, applying the slurry to a component surface on which the aluminum diffusion layer is to be created, drying and/or curing by way of a heat treatment at a first temperature, and diffusion annealing at a second temperature.

Abstract: The invention relates to a method for coating work pieces in a vacuum treatment system having a first electrode embodied as a target, which is part of an arc vaporization source. Using the first electrode, an arc is operated with an arc current and vaporizes material. A bias voltage is applied to a bias electrode, which includes a second electrode that is embodied as a work piece holder, together with the work pieces. Metal ion bombardment is carried out either to pretreat the work pieces or in at least one transition from one layer to an adjacent layer of a multilayer system, so that neither a significant material removal nor a significant material buildup occurs, but instead, introduces metal ions into a substrate surface or into a layer of a multilayer system.

Abstract: Provided is a tantalum sputtering target containing 1 mass ppm or more and 100 mass ppm or less of tungsten as an essential component, and having a purity of 99.998% or more excluding tungsten and gas components. Additionally provided is a tantalum sputtering target according to according to the above further containing 0 to 100 mass ppm of molybdenum and/or niobium, excluding 0 mass ppm thereof, wherein the total content of tungsten, molybdenum, and niobium is 1 mass ppm or more and 150 mass ppm or less, and wherein the purity is 99.998% or more excluding tungsten, molybdenum, niobium and gas components. Thereby obtained is a high purity tantalum sputtering target comprising a uniform and fine structure and which enables stable plasma and yields superior film evenness (uniformity).

Abstract: Provided are: a novel electrode which is suitable for use in an input device as typified by a capacitive touch panel sensor, and which has low electrical resistivity and low reflectance; and a method for producing this electrode. This electrode has a multilayer structure comprising a first layer that is formed of an Al film or an Al alloy film and a second layer that is partially nitrided and is formed of an Al alloy containing Al and at least one element selected from the group consisting of Mn, Cu, Ti and Ta.

Abstract: A mask for a vapor deposition apparatus includes an outer frame; a first bar disposed on an inner side of the outer frame and fixed to the outer frame; and a pattern forming portion disposed on the outer frame and the first bar and fixed to the outer frame. The pattern forming portion includes a plurality of mask openings for pattern formation. Each of the plurality of mask openings is disposed along a first direction. The plurality of mask openings are disposed in a second direction orthogonal to the first direction. The first bar is positioned between adjacent two mask openings among the plurality of mask openings when viewed along a third direction orthogonal to the first direction and the second direction, and is in contact with the pattern forming portion.

Abstract: A substrate processing system for sequentially processing substrates includes processing chambers, a transfer unit, and a control unit controlling the processing chambers and the transfer unit. The control unit includes a transfer control unit controlling an operation of the transfer unit, a transfer order setting unit setting a transfer order of substrates to the processing chambers, an accumulation unit for accumulating a film thickness of a formed thin film or the number of processed substrates after completion of previous cleaning or previous pre-coating in the processing chambers, a processing chamber priority determination unit for determining priority of processing the substrates in the processing chambers based on predetermined rules, and an execution instruction unit for executing conditioning in the processing chambers.

Abstract: The invention provides a process for depositing a coating onto particles being pneumatically transported in a tube. The process comprising the steps of providing a tube having an inlet opening and an outlet opening; feeding a carrier gas entraining particles into the tube at or near the inlet opening of the tube to create a particle flow through the tube; and injecting a first self-terminating reactant into the tube via at least one injection point downstream from the inlet opening of the tube for reaction with the particles in the particle flow. The process is suitable for atomic layer deposition and molecular layer deposition. An apparatus for carrying out the process is also disclosed.

Abstract: Embodiments of improved substrate carriers are provided herein. In some embodiments, a substrate carrier, includes: a multi-layered disk having upper and lower layers formed of a continuous material and an electrostatic electrode structure disposed therebetween, wherein the multi-layered disk is dimensioned and arranged so as to have a nominal dimension which exceeds a nominal dimension of a standard substrate size used in the manufacture of light emitting diode devices, and wherein the multi-layered disk is formed symmetrically about a central axis and defines a substantially planar upper surface.

Abstract: A thermochemical treatment installation includes a reaction chamber, at least one gas inlet, and a gas preheater chamber situated between the gas inlet and the reaction chamber. The preheater chamber has a plurality of perforated distribution trays held spaced apart one above another. The preheater chamber also includes, between at least the facing distribution trays, a plurality of walls defining flow paths for a gas stream between said trays.

Abstract: Disclosed herein is a method of forming a multilayer thin film by depositing target particles, detached from a target by plasma discharge of inert gas, on a metal object using a multilayer thin film deposition apparatus and a multilayer thin film formed by the method. More specifically, a sputtering deposition apparatus is used as the multilayer thin film deposition apparatus. The method includes coating a metal object with a coating layer, depositing at least one hardness-enhancing layer on the coating layer, and depositing a color layer on the at least one hardness-enhancing layer.

Abstract: A touch screen panel includes a substrate and a transparent electrode. The transparent electrode is disposed on a display area of the substrate and includes an adhesion layer, a metal layer disposed on the adhesion layer and a protecting layer disposed on the metal layer. A thickness of the metal layer is about 150 ? to about 250 ?. A thickness of the adhesion layer or a thickness of the protecting layer is about 50 ? to about 140 ?.

Abstract: A combination mirror and media display device assembly includes a mirror platform. The mirror platform has a media display device viewing area and a reflective area. A reflectivity of the media display device viewing area is less than a reflectivity of the reflective area. The assembly includes a mounting bracket. The mounting bracket is coupled to the mirror platform. The mounting bracket is open on one side and the opening in the mounting bracket is configured to accept a media display device. A method to place a media display device within a mirror platform assembly includes inserting a media display device through an opening in a mounting bracket, wherein a mirror platform is attached to the mounting bracket and the mirror platform has a media display device viewing area.

Abstract: The object of the present invention is to provide: an etching agent for a titanium-based metal on a semiconductor substrate, which suppresses decomposition of hydrogen peroxide, has a long liquid service life, and has less need for controlling the concentration of hydrogen peroxide in the etching agent, even in the cases where the etching agent is used for a semiconductor substrate having the titanium-based metal and a metallic copper or a metal alloy; an etching method; and an etching agent preparation liquid for use by mixing with hydrogen peroxide.

Abstract: A chemical process captures and convert hydrogen sulfide (H2S) gas into elemental sulfur, polysulfide, sulfur dioxide and/or sulfuric acid while regenerating sodium hydroxide capture agent for further use in an initial H2S capture step. Processing may include initial sodium hydroxide scrubbing of gas streams containing H2S, electrochemical regeneration of the sodium hydroxide from sodium hydrosulfide or sodium sulfide, recovery of sulfur and/or sulfur dioxide from the electrochemical processing, and production of sulfuric acid from such sulfur and/or sulfur dioxide.

Abstract: A bipolar plate for an electrolyzer, particularly a PEM electrolyzer, is formed with a central region and a peripheral region surrounding the central region. With a view to cost-effective production of the bipolar plate, the central region is made of metal sheet and the peripheral region is formed from a plastic frame. The plastic frame is made of at least one thermoplastic, particularly at least one high-temperature thermoplastic, and is injection-molded around the sheet metal.

Abstract: The present invention discloses a modular health gas generator, more particularly, to a modular health gas generator with an automatic circulation and a cooling function. Then, the gas production rate of the hydrogen-oxygen gas can be controlled by a plurality of freely detachable electrolytic tanks. The invention comprises an inner tank and the plurality of detachable electrolytic tanks. In application, a hollow portion of each electrolytic tank can be inputted or supplied the liquid water from the inner tank. The liquid water is electrolyzed in the electrolytic tank to generate the hydrogen-oxygen gas and be output to the inner tank, and then the hydrogen-oxygen gas will be further outputted through a gas outlet of the inner tank.

Abstract: According to an embodiment, a nuclear fuel material recovery method of recovering a nuclear fuel material containing thorium metal by reprocessing an oxide of a nuclear fuel material containing thorium oxide in a spent fuel is provided. The method has: a first electrolytic reduction step of electrolytically reducing thorium oxide in a first molten salt of alkaline-earth metal halide; a first reduction product washing step of washing a reduction product; and a main electrolytic separation step of separating the reduction product. The first molten salt further contains alkali metal halide, and contains at least one out of a group consisting of calcium chloride, magnesium chloride, calcium fluoride and magnesium fluoride. The method may further has a second electrolytic reduction step of electrolytically reducing uranium oxide, plutonium oxide, and minor actinoid oxide in a second molten salt of alkali metal halide.

Abstract: According to an embodiment of the present invention, a method for producing a duplicate of a nano-pattern texture of a surface of an object through electroforming using an imprint mold comprises selecting the object having the nano-pattern texture, disposing the selected object and pretreating a surface of the object by washing, drying and then forming a nano-thin film thereto to block transfer of impurities, metallizing a surface of the plastic mold through, e.g., vapor deposition, spraying, and wet silver mirror reaction, and performing a first electroforming of the surface of the plastic mold, and repeating to thus manufacture a plurality of metal module master molds.

Abstract: The invention relates to a method for coating an organic or metallic material by covalent grafting of at least one organic compound A having at least one aromatic group substituted with a diazonium function, on a surface of said material, characterized in that the material is porous or fibrillar having a geometric surface area of at least 10 cm2 of material, and in that said method includes a step of continuous imposition of a non-zero pulsed current in an intensiostatic mode on the surface of the material in order to electrochemically reduce the diazonium ion or ions. The invention further relates to the resulting composite materials and to the use of such materials for manufacturing electrodes.

Abstract: A rare earth permanent magnet is prepared by immersing a portion of a sintered magnet body of R1—Fe—B composition (wherein R1 is a rare earth element) in an electrodepositing bath of a powder dispersed in a solvent, the powder comprising an oxide, fluoride, oxyfluoride, hydride or rare earth alloy of a rare earth element, effecting electrodeposition for letting the powder deposit on a region of the surface of the magnet body, and heat treating the magnet body with the powder deposited thereon at a temperature below the sintering temperature in vacuum or in an inert gas.

Abstract: Techniques or processes for providing markings on products are disclosed. In one embodiment, the products have housings and the markings are to be provided on sub-surfaces of the housings. For example, a housing for a particular product can include an outer housing surface and the markings can be provided on a sub-surface the outer housing surface yet still be visible from the outside of the housing. Since the markings are beneath the surface of the housing, the markings are durable.

Abstract: A method for surface treatment of aluminum alloys for forms an oxidation film in the aluminum alloys for casting by adding a metallic anion compound to an electrolytic solution. The method can prevent cracks from occurring on a surface of the aluminum alloys for casting at the time of applying an anodizing method.

Abstract: According to the disclosed embodiments, an advanced crucible support system is described that allows for greater heat flow to and from the bottom of a crucible, preferably while also preventing excessive heat from reaching a heat exchanger. In particular, a support base is described that includes one or more vents enabling improved heat flow throughout the system. Also, according to one or more additional embodiments, the functionality of the crucible support is adapted to be leveraged by a crucible manipulating device. For example, the support plate may have a plurality of slots for insertion of a “lifting arm”, such that the entire support plate assembly, as well as the crucible itself while on the support assembly, may be lifted and transported as a single unit.

Abstract: A crucible having a top surface, a bottom surface opposite to the top surface, and a tubular side surface located between the top surface and the bottom surface, a resistive heater provided outside of the crucible and made of carbon, a source material provided in the crucible, and a seed crystal provided to face the source material in the crucible are prepared. A silicon carbide single crystal is grown on the seed crystal by sublimating the source material with the resistive heater. In the step of growing a silicon carbide single crystal, a value obtained by dividing a value of a current flowing through the resistive heater by a cross-sectional area of the resistive heater perpendicular to a direction in which the current flows is maintained at 5 A/mm2 or less.

Abstract: Embodiments provided herein generally relate to an apparatus for delivering gas to a semiconductor processing chamber. An upper quartz dome of an epitaxial semiconductor processing chamber has a plurality of holes formed therein and precursor gases are provided into a processing volume of the chamber through the holes of the upper dome. Gas delivery tubes extend from the holes in the dome to a flange plate where the tubes are coupled to gas delivery lines. The gas delivery apparatus enables gases to be delivered to the processing volume above a substrate through the quartz upper dome.

Abstract: In some embodiments, the present disclosure pertains to methods of forming single-crystal graphenes by: (1) cleaning a surface of a catalyst; (2) annealing the surface of the catalyst; (3) applying a carbon source to the surface of the catalyst; and (4) growing single-crystal graphene on the surface of the catalyst from the carbon source. Further embodiments of the present disclosure also include a step of separating the formed single-crystal graphene from the surface of the catalyst. In some embodiments, the methods of the present disclosure also include a step of transferring the formed single-crystal graphene to a substrate. Additional embodiments of the present disclosure also include a step of growing stacks of single crystals of graphene.

Abstract: Disclosed are methods and tools for rapidly aligning reads to a reference sequence. These methods and tools employ Bloom filters or similar set membership testers to perform the alignment. The reads may be short sequences of nucleic acids or other biological molecules and the reference sequences may be sequences of genomes, chromosomes, etc. The Bloom filters include a collection of hash functions, a bit array, and associated logic for applying reads to the filter. Each filter, and there may be multiple of these used in a particular application, is used to determine whether an applied read is present in a reference sequence. Each Bloom filter is associated with a single reference sequence such as the sequence of a particular chromosome. In one example, chromosomal abundance is determined by aligning reads from a sequencer to multiple chromosomes, each having an associated Bloom filter or other set membership tester.

Abstract: The present invention concerns methods for removing sulfur from yarn comprising the steps of: a) contacting never-dried polymeric yarn with an aqueous base, the polymer comprising imidazole groups and said polymer comprising sulfur atoms characterized as being in the form of sulfate anions; b) contacting the yarn with an aqueous acid solution of pH 5 or lower; and c) rinsing the yarn.

Abstract: The present invention is directed to nanofiber yarns, ribbons, and sheets; to methods of making said yarns, ribbons, and sheets; and to applications of said yarns, ribbons, and sheets. In some embodiments, the nanotube yarns, ribbons, and sheets comprise carbon nanotubes. Particularly, such carbon nanotube yarns of the present invention provide unique properties and property combinations such as extreme toughness, resistance to failure at knots, high electrical and thermal conductivities, high absorption of energy that occurs reversibly, up to 13% strain-to-failure compared with the few percent strain-to-failure of other fibers with similar toughness, very high resistance to creep, retention of strength even when heated in air at 450° C. for one hour, and very high radiation and UV resistance, even when irradiated in air. Furthermore these nanotube yarns can be spun as one micron diameter yarns and plied at will to make two-fold, four-fold, and higher fold yarns.

Abstract: A spun yarn includes a bicomponent staple fiber comprising poly(trimethylene terephthalate) and cotton staple fiber, where the poly(trimethylene terephthalate) is present at a level of at least 1 wt % and less than 20 wt % based on total weight of the spun yarn.

Abstract: A composite fiber may include at least one reinforcing filament formed of a first material. A second material maybe systematically deposited in a printed onto the at least one reinforcing filament such that at least one of a length, a width, and a thickness of the second material varies across a surface of the at least one reinforcing filament. The printed pattern may alter one or more properties of a composite structure containing the composite fiber.