Abstract: A wearable thermometer patch for continuous wearing by a user includes a circuit substrate that includes an electric circuit, a battery holder mounted in the circuit substrate, and a detachable cover layer on the battery holder. The battery holder can hold a replaceable battery to supply power to the electric circuit. A temperature probe unit in connection with the electric circuit includes one or more temperature sensors in electric connection with the electric circuit in the circuit substrate. The one or more temperature sensors each can measure temperatures near the user's skin to produce one or more temperature values.

Abstract: An actively-powered medical system for monitoring a body temperature of a patient includes a temperature data logger patch with wireless data communication includes a sealed, flexible battery comprising a printed electrochemical cell with an anode and a cathode, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transceiver and an antenna. In one example, the patch is configured to conform to a curved surface of the target subject. In another example, the patch is used in an actively-powered medical system for monitoring a body temperature of a patient, and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of communication with the wireless communication transceiver of the patch via an electromagnetic field.

Abstract: A device for monitoring a state of a living being includes a first sensor, a second sensor and an evaluation device. The first sensor non-invasively generates a measurement value based on a content of ammonia in the sweat of the living being. The second sensor generates a measurement value with respect to the respiration or the cardiac activity of the living being. The evaluation device generates a scalar measure of a stress of the living being based on the measurement values of the first and second sensors. Furthermore, the invention relates to a corresponding method.

Abstract: The present invention relates to a portable device for determining a heart rate of a person, said portable device comprising: a heart rate measurement unit for measuring the heart rate of the person over time to generate a heart rate signal, a motion measurement unit for measuring the motion of a body part of the person over time to generate a motion signal, and a processing unit which is adapted to measure a signal quality of the heart rate signal, to calculate the heart rate based on the heart rate signal if said signal quality is above a predefined threshold, and to estimate the heart rate based on the motion signal if said signal quality is below said threshold.

Abstract: A health monitoring unit includes a hardware processor, a memory, a display, and a graphical user interface (GUI) stored in the memory. The GUI is executed by the processor to provide a selection screen enabling a user to select parameters for viewing on the display from among health parameters of a living subject being tracked by the health monitoring unit. The GUI also presents a main screen showing the parameters selected by the user, the main screen including an icon for communicating a hypotension probability index (HPI) status of the living subject. In addition, the GUI overlays an alarm screen as a pop-up on the display if the HPI of the living subject satisfies a predetermined risk criteria, and enables the user to access an HPI diagnostic screen showing values for a subset of the health parameters identified as predictive of a future hypotension event for the living subject.

Abstract: Some embodiments relate to a device, method, and/or computer-readable medium storing processor-executable process steps for processing a photoplethysmographic (“PPG”) signal in a monitoring device that monitors a property of blood flow. In some embodiments, the processing includes obtaining a first digital signal representing a detected light signal having a non-pulsatile (e.g., DC) component and a pulsatile component (e.g., AC). An offset control signal is generated from an estimation of the non-pulsatile component and a second digital signal is generated after subtracting the offset control signal from the detected light signal and applying a gain to the subtracted signal. A reconstructed signal is generated that is calculated from the gain and one or more of (i) the first digital signal, and (ii) the second digital signal and the offset control signal.

Abstract: Described here are systems and methods for providing a non-invasive and continuous quantitative measurement of left ventricular stroke volume (“SV”) and flow volume during a magnetic resonance imaging (“MRI”) scan. In general, the method estimates quantitative measurements of SV from magnetohydrodynamic (“MHD”] voltages generated by blood flowing through the subject's vasculature while the subject is positioned in the magnetic field of an MRI system. A rapid calibration technique is provided to convert MHD voltages to estimates of blood flow, from which quantitative measurements of SV can be computed.

Abstract: Methods and systems for characterizing tissue of a subject include acquiring and receiving data for a plurality of time series of fluorescence images, identifying one or more attributes of the data relevant to a clinical characterization of the tissue, and categorizing the data into clusters based on the attributes such that the data in the same cluster are more similar to each other than the data in different clusters, wherein the clusters characterize the tissue. The methods and systems further include receiving data for a subject time series of fluorescence images, associating a respective cluster with each of a plurality of subregions in the subject time series of fluorescence images, and generating a subject spatial map based on the clusters for the plurality of subregions in the subject time series of fluorescence images. The generated spatial maps may then be used as input for tissue diagnostics using supervised machine learning.

Abstract: One or more sensors and/or sensing techniques are used individually or in combination to detect and/or measure heart rate and/or heart rate variability. The sensors may be wearable and/or portable and may operate on different principles and may include different power profiles. The sensors and/or sensing techniques may be used at the same time or at different times that may overlap partially or completely, or may be mutually exclusive. A controller may select one or more sensors and/or sensing techniques based on operating conditions and/or based on conservation of power.

Abstract: In an automated methodology for in vivo image-guided cell patch clamping, a cell patch clamping device is moved into position and targeted to a specific cell using automated image-guided techniques. Cell contact is determined by analyzing the temporal series of measured resistance levels at the clamping device as it is moved. The difference between successive resistance levels is compared to a threshold, which must be exceeded before cell contact is assumed. Pneumatic control methods are used to achieve gigaseal formation and cell break-in, leading to whole-cell patch clamp formation. An automated robotic system capable of performing this methodology automatically performs patch clamping in vivo, automatically locating cells through image guidance and by analyzing the temporal sequence of electrode impedance changes.

Abstract: Techniques and devices for implementing the techniques for adjusting atrial arrhythmia detection based on analysis of one or more P-wave sensing windows associated with one or more R-waves. An implantable medical device may determine signal characteristics of the cardiac signal within the P-wave sensing window, determine whether the cardiac signal within the sensing window corresponds to a P-wave based on the determined signal characteristics, determine a signal to noise ratio of the cardiac signal within the sensing window, update the arrhythmia score when the P wave is identified in the sensing window and the determined signal to noise ratio satisfies a signal to noise threshold.

Abstract: A medical device, such as an extra-cardiovascular implantable cardioverter defibrillator (ICD), senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal acquired by a second sensing channel in response to each sensed R-wave. The medical device determines at least one noise parameter from a group of the stored time segments of the second cardiac electrical signal, detects noise based on the noise parameter, and withholds detection of a tachyarrhythmia episode in response to detecting the noise.

Abstract: A catheter with basket-shaped electrode assembly with spines configured for hyper-flexing in a predetermined, predictable manner when a compressive force acts on the assembly from either its distal end or its proximal end. At least one spine has at least one region of greater (or hyper) flexibility that allows the electrode assembly to deform, for example, compress, for absorbing and dampening excessive force that may otherwise cause damage or injury to tissue wall in contact with the assembly, without compromising the structure and stiffness of the remaining regions of the spine, including its distal and proximal regions. The one or more regions of greater flexibility in the spine allow the spine to flex into a generally V-shape configuration or a generally U-shape configuration.

Abstract: A medical device system, such as an extra-cardiovascular implantable cardioverter defibrillator ICD, senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal in response to each sensed R-wave. The medical device system determines a morphology parameter correlated to signal noise from time segments of the second cardiac electrical signal, detects a noisy signal segment based on the signal morphology parameter; and withholds detection of a tachyarrhythmia episode in response to detecting a threshold number of noisy signal segments.

Abstract: A system for detecting an atrial tachyarrhythmia episode includes a medical device having sensing circuitry configured to receive a cardiac electrical signal from electrodes coupled to the medical device and a processor configured to detect an atrial tachyarrhythmia episode in response to a time duration of the cardiac electrical signal classified as an atrial tachyarrhythmia being greater than or equal to a first detection threshold. The processor is configured to determine if detection threshold adjustment criteria are met based on at least the detected first atrial tachyarrhythmia episode and adjust the first detection threshold to a second detection threshold different than the first detection threshold in response to the detection threshold adjustment criteria being met.

Abstract: A medical device system, such as an extra-cardiovascular implantable cardioverter defibrillator ICD, senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal in response to each sensed R-wave. The medical device system determines a morphology parameter correlated to signal noise from time segments of the second cardiac electrical signal, detects a noisy signal segment based on the signal morphology parameter; and withholds detection of a tachyarrhythmia episode in response to detecting a threshold number of noisy signal segments.

Abstract: Systems and methods for monitoring medical procedures. Particular embodiment's relate to monitoring medical procedures performed in operating room environments through the use of various types of sensors, including for example, wireless electroencephalography (EEG) monitoring systems. Presented are systems and methods directed to a monitor medical procedures, including in particular the mental state of medical personnel associated with such procedures. Exemplary embodiment's of the present disclosure relate to systems and methods for monitoring medical procedures. Particular embodiment's relate to monitoring medical procedures performed in operating room environments through the use of various types of sensors, including for example, wireless electroencephalography (EEG) monitoring systems.

Abstract: An electroencephalogram electrode includes: a bottom portion on which a connection member is placed, the connection member which is configured to supply a biological signal that is acquired from a subject through conductive gel, to an external apparatus; an annular wall which annularly extends from the bottom portion in a contact direction with respect to the subject; and a plurality of barb members which are disposed in a holding space for the conductive gel that is located inside the annular wall, and which elongate from the bottom portion in the contact direction with respect to the subject.

Abstract: A neurofeedback headgear is provided. The neurofeedback headgear comprises a head receiving portion, a brim portion, an EEG sensor assembly and an emitter. The EEG sensor assembly includes one or more sensing electrodes located on the inner side of the head receiving portion, for contacting the forehead of the user and sensing brain activity when the headgear is worn. The EEG sensor assembly also includes a microcontroller in communication with the sensing electrodes, the microcontroller being mounted to the inner side of the head receiving portion and concealed under the concealing layer. The emitter emits a visual feedback according to the state of brain activity determined by the microcontroller, the visual feedback being located within a field of vision of the user when the headgear is worn by the user.

Abstract: A device for reducing traumatic brain injury comprises a first sensor, a first linkage element, and a processing element. The first sensor is coupled to a head component and configured to measure an acceleration of a user's head and to generate a sequence of real-time measured samples. The first linkage element is configured to connect the head component to a body component and is able to switch between a first state in which it is relatively flexible and a second state in which it is relatively rigid. The first linkage element is switched from its first state to its second state by a locking signal. The processing element is configured to receive the real-time measured samples and to generate the locking signal when each of a portion of the real-time measured samples is greater than one of a corresponding portion of a plurality of dynamic concussion thresholds.

Abstract: A PET-MRI apparatus according to an embodiment includes a static magnetic field magnet, a gradient coil, a birdcage-type radio frequency coil, and at least one PET detector. The static magnetic field magnet is configured to generate a static magnetic field. The gradient coil is configured to apply a gradient magnetic field to a subject placed in the static magnetic field. The radio frequency coil includes two end rings and a plurality of rungs arranged at intervals along a circumferential direction of the end rings and is configured to transmit a radio frequency pulse or to receive a magnetic resonance signal from the subject. Further, the PET detector is housed inside a conductor structuring the rungs of the radio frequency coil.

Abstract: An electrophysiology map, for example a map of arrhythmic substrate, can be generated by acquiring both geometry information and electrophysiology information pertaining to an anatomical region, and associating the acquired geometry and electrophysiology information as a plurality of electrophysiology data points. A user can select two (or more) electrophysiological characteristics for display, and can further elect to apply various filters to the selected electrophysiological characteristics. The user can also define various relationships (e.g., Boolean ANDS, ORs, and the like) between the selected and/or filtered characteristics. The user-selected filtering criteria can be applied to the electrophysiology data points to output various subsets thereof. These subsets can then be graphically rendered using various combinations of colorscale, monochrome scale, and iconography, for example as a three-dimensional cardiac electrophysiology model.

Abstract: Disclosed are an electronic device and operating method thereof. The present invention includes recognizing an electrode initially in contact with the user's body part among a plurality of electrodes as a first pair, recognizing the rest of the electrodes contacted with the user's body as a second pair, measuring a current flowing between the recognized first and second pairs, determining a biometric information of the user based on the measured current and load, and outputting the determined biometric information.

Abstract: A body characteristic measurement method causing a computer to execute a process, the process includes: determining a gait of a quadruped based on accelerations, acquired from a multi-axis acceleration sensor attached to the chest of the quadruped, in multiple axial directions; and determining, if the determined gait is gallop or canter, an injury risk of the quadruped based on a waveform of a positive half-wave region of acceleration in a movement direction of the quadruped in the case where an increase in the acceleration in the movement direction of the quadruped is defined as positive.

Abstract: An apparatus for remote controlled physical activity monitoring, the apparatus comprising: at least one orientation measurer, wearable on at least one body part of a user, configured to measure orientation of a body part wearing the orientation measurer during a physical activity of the user, at least one pressure meter, wearable on at least one body part of the user, configured to measure pressure applied by muscle of a body part wearing the pressure meter during the physical activity of the user, a computer processor, associated with the orientation measurer and pressure meter, configured to derive monitoring control data from the measured orientation and pressure, and a data transmitter, associated with the computer processor, configured to transmit the monitoring control data to a physical activity monitoring device, and thereby to remotely control a monitoring of the physical activity of the user by the physical activity monitoring device.

Abstract: An apparatus for estimating a substance in blood in a noninvasive manner is provided. The apparatus includes a light source configured to emit light to skin of a user; a plurality of detectors which are disposed at different distances from the light source and configured to detect light signals from the light returning from the skin; and a processor configured to determine a similarity between at least two light signals among the detected light signals and estimate the substance in blood based on the similarity.

Abstract: Provided is a multi-channel brain-functional near infrared spectroscopy device capable of easily levelling detector noise.

Abstract: Transdermally emitted gasses are detected by applying a dermal sampling strip to the skin of a biological subject, capturing the gasses in a vapor space in the dermal sampling strip, and analyzing for at least one such gas captured in the vapor space of the dermal sampling strip. Analysis is preferably performed using an electrocatalytic cell, which can be mounted on the dermal sampling strip and form a wall of the vapor space.

Abstract: The invention relates to a system and a non-invasive method for examining at least parts of the blood fractions, designed for examination of the blood fractions on the basis of at least one magnetic resonance spectroscopy of a human body part, in particular of the human finger. The invention also relates to the use of said system.

Abstract: An embodiment relates generally to an improved method and apparatus for modulating the amplitude and rotation of the plane of polarization of linearly polarized light for multiple uses but primarily as part of a noninvasive glucose monitoring system. As compared to previous monitoring systems, an embodiment provides faster monitoring while maintaining or even reducing noise and minimizing system complexity. Embodiments described herein address these concerns with a modulation and compensation approach that both uses a single high speed device and also modulation of the lasers.

Abstract: This disclosure relates to a system and method for drawing blood from a user by skin puncture instead of venous puncture and storing it for analysis. The system includes a receptacle configured to engage an area of skin of the user at a blood draw location and store blood drawn from the user; a lancet device disposed within the receptacle configured to puncture the skin of the user at the blood draw location; a vacuum device configured to reduce a pressure within the receptacle such that the skin at the blood draw location is drawn into the receptacle before the lancet device punctures the skin, and to enhance blood flow while blood is drawn from the user; and a housing configured to house the receptacle, the lancet device, and the vacuum device. The receptacle, the lancet device, and the vacuum device may be modular and removably coupled with the housing.

Abstract: The present invention relates to a blood lancet used in capillary blood sampling, in which the blood lancet is unitarily moulded with an elastic member for providing actuation force. In a preferred embodiment, the blood lancet (100) comprises a needle component (120) having a forward end (122) and a rearward end (124), an elastic member (140) disposed in the rearward end (124), and a detachable safety cap (160) disposed at the forward end (122), both of which are unitarily moulded to the needle component (120).

Abstract: A drowsiness detection method that causes a computer to execute a process, the process includes: performing frequency analysis on heartbeat data obtained from a subject; and determining a state of the subject by calculating entropy in a predetermined frequency bandwidth with a peak as a reference, where the peak is within a predetermined frequency range of frequency distribution obtained from the frequency analysis result, determining that the subject is in a relaxation state in a case where the calculated entropy is less than a predetermined threshold value, and determining that the subject is in a drowsiness state in a case where the entropy is equal to or greater than the threshold value.

Abstract: We report a method of determining an occurrence of an epileptic convulsive seizure in a patient, comprising: receiving body data from a patient during a first time period, determining a work level relating to said first time period at least based partially upon said body data; determining whether said work level exceeds an extreme work level threshold; performing a responsive action, in response to a determination that said work level exceeds said extreme work level threshold. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

Abstract: A watch-like early allergy detection, notification and management system is equipped with a motion detector as well as one or more physiological sensors to measure heart rate, skin color change, skin galvanic response, oxygen saturation and blood pressure to detect early symptoms of an allergic reaction. False alarms are reduced by simultaneously measuring ambient temperature and physical activity of the subject. Sudden onset of skin itch, redness, sweating, increase in heart rate or a drop in blood pressure without a preceding hot ambient condition or strenuous physical activity is interpreted as an allergic reaction. The system is also equipped with a subject locator and a GPS receiver to assist a caregiver in finding the subject rapidly. The system further features a medication compartment to start managing the allergic reaction quickly. The system is particularly beneficial for children that may become scared or hide away upon onset of an allergic reaction.

Abstract: A skin diagnosis device includes an imaging unit (17) that images a face of a person who is subjected to a diagnosis, a facial part analyzer (18) that analyzes a facial part, based on a facial image of the person who is subjected to the diagnosis, an irradiation management unit (13) that specifies positions of eyes of the person who is subjected to the diagnosis from an analysis result of the facial part, and determines a whole of a facial region except for the eye positions as an irradiation region, an irradiation unit (15) that irradiates the determined irradiation region with light, and a skin diagnosis analyzer (19) that performs a skin diagnosis, based on the facial image, which is imaged by being irradiated with the light, of the person who is subjected to the diagnosis. It is possible to protect the eyes of the person who is subjected to the diagnosis, and to relieve stress of the person who is subjected to the diagnosis.

Abstract: A wound assessment device is provided which can include any number of features. In one embodiment, the wound assessment device comprises a hands-free device that includes a camera, additional sensors, electronics including a processor, a non-transitory computer-readable storage medium, an energy source, and a display. The wound assessment device can be configured to document the healing process of a wound, and overlay a digital ruler and information pertaining to the wound and the patient onto images taken of the wound. Methods of use are also provided.

Abstract: A method and system for actively monitoring anterior cruciate ligament (ACL) strain experienced at the knee joint during athletic activity or dynamic movement. Sensors are used in proximity of the knee joint to actively record parameters such as flexion angle and ground impact force at the knee joint. Sensor measurements are then inputted into a processing unit that will quantify a tibial shear force (TSF) value based on the sensor outputs and dynamically generate user feedback and/or warning signals when unsafe levels of TSF conducive to ACL injury are detected.

Abstract: An apparatus and method for creating a three dimensional imaging system is disclosed. There is a first source of laser light and a second source of laser light having a wavelength different from the wavelength of the laser light of the first source. The laser light from the first and second sources are combined, and the combined laser light is transmitted to a scanner. The scanner further transmits the combined light to a surface to be imaged.

Abstract: A distributed computer system 100 and method that will serve for recording sleep of at least one user using a mobile subscriber terminal 104 and a peripheral device 102 arranged to communicate with the mobile subscriber terminal 104. The present invention records the sleep parameters of family members by providing third party applications and a plurality of peripheral devices communicating with the mobile subscriber terminals according to the age and interest of each family member. The peripheral devices are configured to communicate sleep data to the mobile subscriber terminals and further to a data storage application 120 stored on a server computer 130. For a child user the peripheral device 102 and mobile subscriber terminal 104 may be incorporated into a soft toy 110.

Abstract: A device for use in the medical and hospital sector for the diagnosis, induced regeneration of tissue by means of therapeutic percutaneous electrolysis and targeted electro-stimulation based on the use of at least one bipolar needle that includes within a very small area of two electrodes located at the exterior and interior conductor of said bipolar needle, limiting the tissue to be treated within the bevel area of the needle without affecting the surrounding healthy tissue in which said bipolar needle is applied the necessary electrical signals for diagnosing the degree of degeneration and to calculate the necessary electrical charge for treating the damaged tissue while controlling said current in a manner that eliminates the contraindications that currently exist.

Abstract: Methods and apparatus are provided for planning and delivering radiation treatments by modalities which involve moving a radiation source along a trajectory relative to a subject while delivering radiation to the subject. In some embodiments the radiation source is moved continuously along the trajectory while in some embodiments the radiation source is moved intermittently. Some embodiments involve the optimization of the radiation delivery plan to meet various optimization goals while meeting a number of constraints, For each of a number of control points along a trajectory, a radiation delivery plan may comprise: a set of motion axes parameters, a set of beam shape parameters and a beam intensity.

Abstract: Various embodiments described herein generally relate to a wearable device collecting data from one or more sensors related to the activity of a person and the wearable device communicating the physiological data sensed or information that corresponds to the physiological data sensed to a recommendation network. In certain instances the recommendation network may analyze the physiological data or information that corresponds to the physiological data when composing messages. The messages composed by the recommendation network may include information that is skewed, biased, or otherwise altered from actual data sensed at a wearable device.

Abstract: A conductive fabric including a fabric and a wiring provided on the fabric, wherein the wiring has a first insulating layer formed on the fabric, a conductive layer provided on the first insulating layer, and a second insulating layer provided on the conductive layer, and wherein in a stretching test in which the conductive fabric is stretched by a stretching rate of 10% in a stepwise manner up to a stretching rate of 100% in a longitudinal direction of the wiring, a resistance change ratio when stretched at a stretching rate of 100% is 100-fold or less, the resistance change ratio when stretched at a stretching rate of 100% being represented by an equation: R100/ R0 (fold), where R0 is a resistance value at a stretching rate of 0% and R100 is a resistance value when stretched at a stretching rate of 100%. The conductive fabric is capable of maintaining high electrical conductivity even upon being stretched.

Abstract: A proprioceptive enhancement device, including methods of use, is described. The proprioceptive enhancement device includes a sock-like garment, with or without a shoe or other footwear, which mechanically and electrically stimulates cutaneous, subcutaneous, and deep tissue mechanoreceptors and proprioceptors to provide feedback to the user. The feedback causes the user to adjust weight distribution during athletic and non-athletic activities for optimal performance and increased overall health. The device includes additional configurations for electrically grounding the wearer to the earth, which may provide additional health benefits. The disclosure includes a method of using the proprioceptive enhancement device to treat wounds of the foot, including but not limited to venous stasis ulcers, arterial insufficient ulcers, traumatic wounds, and the like.

Abstract: Provided herein is a probe for ultrasound imaging of tissue. The probe comprises an optical relay having an optically absorbing coating at the distal end of the probe for generating ultrasound from excitation light via the photoacoustic effect, wherein the generated ultrasound propagates as an ultrasound beam into the tissue; and an ultrasound receiver separate from the optical relay. The optical relay is configured to receive as input a time-varying spatial pattern of excitation light at the proximal end of the probe and to transmit the excitation light to the distal end of the probe to illuminate the optically absorbing coating in accordance with said time-varying spatial pattern, thereby generating ultrasound from the excitation light via the photoacoustic effect to propagate as a scanning ultrasound beam into the tissue. The ultrasound receiver is configured to receive reflections of the ultrasound from tissue. Such an ultrasound probe may be incorporated, for example, into a transseptal puncture needle.

Abstract: Method and apparatus for inserting at least a portion of a sensor into a patient is provided.

Abstract: In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.

Abstract: A method for determining a duration of a critical state of a driver of a vehicle. In this method, a state signal is read in, which represents a state of the driver detected using a sensor unit of the vehicle. It is subsequently checked whether the state signal represents the critical state or a non-critical state of the driver. If the state signal represents the critical state, a counter value of a counter representing the duration of the critical state is incremented. If the state signal represents the non-critical state, the counter value is held constant. If after the expiration of a reference hold time the state signal represents the non-critical state, the critical value is decremented.

Abstract: The present invention relates to a processing device for processing accelerometer signals (17, 17a-c) for use in monitoring vital signs of a subject, comprising—a signal input unit (38) for inputting an accelerometer signal (17, 17a-c) of the subject in time, the accelerometer signal (17, 17a-c) being related to at least one physiological event being a cardiovascular or a respiratory event of the subject and measured for at least one spatial direction, an envelope determination unit (19, 40) for determining an envelope signal (21) of the input accelerometer signal (17, 17a-c), a calculation unit (44) for calculating an adjustment factor (43) based on an estimated time interval (45) between a first and a second physiological event of the subject, and a signal adjustment unit (42) for adjusting the determined envelope signal (21) by multiplying the envelope signal (21) with the calculated adjustment factor (43).