Patents Issued in February 13, 2018
-
Patent number: 9889051Abstract: A disposable absorbent article may comprise a chassis and an ear. The chassis comprises a liquid permeable topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet. The ear comprises an elastomeric material and a first substrate joined to the elastomeric material. The ear has a first void region adjacent the proximal edge of the ear. The ear is joined to the chassis by at least one mechanical bond that engages the elastomeric material.Type: GrantFiled: February 26, 2014Date of Patent: February 13, 2018Assignee: The Procter & Gamble CompanyInventors: Joseph Hung Lam, Michael Irwin Lawson, Egon Loeffler, Douglas Michael Graham, Kaneeta Kimble
-
Patent number: 9889052Abstract: An absorbent article has a lower absorbing core and an upper absorbing core. Each absorbing core includes a liquid-holding material and a liquid-permeable core-wrapping sheet. The liquid-holding material is covered by the liquid-permeable core-wrapping sheet, but it also has an exposed portion not covered by the liquid-permeable core-wrapping sheet. The exposed portions of the lower absorbing core and the upper absorbing core face each other and the liquid-holding materials are connected with each other at the exposed portion. Because the liquid-holding material of the upper absorbing core is in direct contact with the liquid-holding material of the lower absorbing core, the area provides a path through which liquid flows smoothly from the upper absorbing core to the lower absorbing core. Also, because the upper and lower liquid-holding materials are covered by the core-wrapping sheets, deformation of the liquid-holding materials is prevented.Type: GrantFiled: January 15, 2015Date of Patent: February 13, 2018Assignees: LIVEDO USA, INC., LIVEDO CORPORATIONInventor: Takuya Hishikawa
-
Patent number: 9889053Abstract: A method for a two person rescue team to rescue an incapacitated person from a hazardous environment includes a wheeled platform with a contoured recess shaped to accommodate an air pack. The platform is sufficiently low to the ground so that a transported person, as well as the rescue personnel can be kept below the heat in an inflamed building. The platform straddles a water hose which is used as an escape path by the rescue team to extract the incapacitated person.Type: GrantFiled: December 14, 2015Date of Patent: February 13, 2018Inventor: Wesley Wyatt Caskey
-
Patent number: 9889054Abstract: A fail-safe release mechanism for use with patient positioning support apparati having a base structure and a patient support structure, to prevent collapse of the patient support during disconnection of the patient support structure from the base structure.Type: GrantFiled: August 11, 2016Date of Patent: February 13, 2018Assignee: Warsaw Orthopedic, Inc.Inventor: Roger P. Jackson
-
Patent number: 9889055Abstract: An electrical connection system that can feed power, signal, data, and communication lines into a rotating or static patient support system in an infant warming device.Type: GrantFiled: March 15, 2014Date of Patent: February 13, 2018Assignee: SEGARS CALIFORNIA PARTNERS, LPInventor: Peter D. Sabota
-
Patent number: 9889056Abstract: A medical apparatus for extending the neck of a patient without manually lifting the patient. This apparatus has a gel pad assembly encapsulating an inflatable bag connected to two hoses for inflation and deflation purposes. The inflatable bag is positioned beneath the shoulders, thereby lifting the shoulders and hence extending the neck when the inflatable bag is inflated.Type: GrantFiled: October 26, 2015Date of Patent: February 13, 2018Assignee: University of DammamInventor: Hassan Mohammed A. Al Bisher
-
Patent number: 9889057Abstract: Disclosed is a retractable handle system for a casket. A casket having retractable handles includes a casket box with a casket lid openably coupled to it. A base is coupled to the casket box. The base includes a panel having a length and a width similar to the length and width of the casket box. Spacers are coupled to the panel to form channels. Arms are slidably located in the channels. At least four bars are coupled to the arms. The bars may have forty-five degree angled ends which allow the bars to abut each other when they are in a closed position causing them to no longer appear as handles on the casket box. Sliding the arms causes the bars to move from the closed to open position.Type: GrantFiled: March 20, 2017Date of Patent: February 13, 2018Inventor: LaVerl A. Womack
-
Patent number: 9889058Abstract: An orthosis includes a first portion and a second portion configured to attach on opposite sides of a joint. An actuator is configured to apply a force between the first and second portions. The actuator includes a first spool and a second spool rotatably mounted to the first portion. An output pulley is mounted to the second portion. A belt has a first end wrapped around the first spool, a second end wrapped around the second spool, and a mid-portion wrapped around the output pulley. The actuator is configured to rotate the first and second spools. The rotation of the first spool pulls the belt a given length, and the rotation of the second spool feeds the belt less than the given length, so as to pull the output pulley towards the first portion to pull the second portion towards the first portion.Type: GrantFiled: March 13, 2014Date of Patent: February 13, 2018Assignee: AlterG, Inc.Inventors: Robert W. Horst, Richard R. Marcus
-
Patent number: 9889059Abstract: A finger joint driving device is provided on a hand and causes a finger joint to be turned. The finger joint driving device includes a first base portion that is mounted on the hand, a first link portion that is turnably provided on the first base portion, a second link portion that is turnably provided on the first link portion, a second base portion that is mounted on the end side of a finger from the first base portion in the hand and is provided on the second link portion so as to relatively approach with respect to and to be separated from the first base portion, and a driving unit that drives the second link portion to be turned.Type: GrantFiled: March 2, 2015Date of Patent: February 13, 2018Assignee: Seiko Epson CorporationInventor: Yutaka Arakawa
-
Patent number: 9889061Abstract: A crutch and method of carrying packages using such crutch are disclosed. The crutch comprises a plurality of metal poles connected together and covered by an insulating material. An outwardly extending finger element along an upper edge on a top of the crutch is configured to detachably mount a package having a hanging loop by draping the hanging loop on the finger element. The crutch includes side poles and a center pole sandwiched between the side poles. A pocket for receiving a package or other item is between the side poles and an enclosure holding a stretchable netting is mounted to the crutch and is configured to enable a user to withdraw the netting from the enclosure and wrap the netting around the package. The user detachably connects a free end of the netting to a portion of crutch to secure the package to the crutch.Type: GrantFiled: June 15, 2015Date of Patent: February 13, 2018Inventor: Lorelei Trask
-
Patent number: 9889062Abstract: An extensible device capable of switch, control, power and connection includes a signal receiving device adapted to receive a control signal and electrically connected to a small power source to control the small power source. The small power source is power-connected to an extensible structure. The extensible structure includes a transmission gear train, whereby a massage device, coupled with one reinforced motor, controllably effects a plurality of massage techniques in conjunction with the at least one extensible device.Type: GrantFiled: May 27, 2015Date of Patent: February 13, 2018Inventor: Jue-Yao Chen
-
Patent number: 9889063Abstract: Methods and systems are disclosed for determining patient compliance for using a compression therapy device. The systems may include a compression therapy sleeve and a controller having a non-transitory memory device. During a therapy session, the controller may record in the memory device operational therapy data obtained from sensors associated with the controller and/or sleeve. The controller may calculate a compliance metric based in part on the therapy data. The controller may then communicate the data or metric to one or more recipients. The methods may include allowing the patient to transfer a removable memory device from the controller to a personal computer, and uploading the therapy data or metric stored on it to a recipient website. Alternative methods may include the patient receiving the metric from the controller at the end of the therapy session, and then providing the metric to a recipient by phone.Type: GrantFiled: June 11, 2013Date of Patent: February 13, 2018Assignee: WRIGHT THERAPY PRODUCTS, INC.Inventors: Carol L. Wright, Gregory Yurko
-
Patent number: 9889064Abstract: Disclosed is a sexual stimulation device that includes a phallus shaped member having a handle opposite a stimulation end. The handle includes a control button for operating the device. The control button is connected to a power source that can activate an oscillating motor, which is attached to a motor head having a motor head attachment and a silicone embedded connector. The motor head oscillates, thereby moving the motor head attachment and the silicone embedded connector therewith. The silicone embedded connector is aligned with a stimulation point at the stimulation end of the device such that when the device is activated, the stimulation point can oscillate. In use, the stimulation end can be inserted into a vagina to contact the g-spot or near the wall of the vagina to stimulate a user.Type: GrantFiled: December 6, 2016Date of Patent: February 13, 2018Inventors: Eddy Olivares, Dan Liu
-
Patent number: 9889065Abstract: A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion includes touch-points or a wave that transmit the tapping motion to skin in contact with the textured portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.Type: GrantFiled: January 4, 2017Date of Patent: February 13, 2018Inventor: Filip Sedic
-
Patent number: 9889066Abstract: Exemplary embodiments of massaging devices are disclosed herein. One exemplary embodiment includes a piston having a longitudinal axis, a massaging head connected to the piston, a motor located on a first side of the longitudinal axis and a handle located on a second side of the longitudinal axis. A drive mechanism for moving the piston and massage head is also included.Type: GrantFiled: June 27, 2014Date of Patent: February 13, 2018Assignee: Good Fortune 5, LLCInventors: Philip C. Danby, John Charles Danby
-
Patent number: 9889067Abstract: An integrated columnar structure is connected to hot and cold water supplies. On the structure is separately mounted on eyewash and faucet. In an alternative embodiment a water bubbler can be substituted for the eyewash. Water passageways within the columnar structure separately supply the appropriate temperature water to the faucet and eyewash/bubbler. Valving mounted on the columnar structure, preferably with an angle oriented at an acute angle to the axis of the column, controls the temperature of water supplied to the faucet. Cold, or slightly tempered, water is supplied to the eyewash.Type: GrantFiled: September 29, 2016Date of Patent: February 13, 2018Assignee: Speakman CompanyInventors: Charles J. Novak, Jeffrey B. Harwanko
-
Patent number: 9889068Abstract: The invention is a novel pillbox for storing medicines that overcomes the deficiencies in existing commercial products. Unlike existing products, in which medicine is loaded into the pillbox by opening a top lid, the present invention is a pillbox that allows side-loading and unloading, thereby eliminating the lids. Because the lids tend to break after extensive use, the elimination of the lids extends the lifetime of the pillbox. Another objective of the invention is to offer the user medicine compartments with sizes that can be easily modified, unlike existing products that only offer medicine compartments with fixed sizes.Type: GrantFiled: July 20, 2017Date of Patent: February 13, 2018Inventor: Ezzat G. Bakhoum
-
Patent number: 9889069Abstract: Interactive medicine management systems and methods comprising integrated elements using a network processor to provide assistance to individuals in order to organize and monitor patient compliance in the administration of one or more medications are provided.Type: GrantFiled: November 23, 2016Date of Patent: February 13, 2018Assignee: One World DMG, Ltd.Inventors: Matthew Coe, Fred Pether, Sean Ely
-
Patent number: 9889070Abstract: The present invention provides a novel curable composition in which a reaction is caused to occur between a hydroperoxide and a thiourea compound to initiate polymerization of a radical polymerizable monomer and which has excellent adhesive properties, moderate curability, and excellent long-term storage stability. The present invention relates to a curable composition (A) containing: a radical polymerizable monomer (a1) having no acidic group; a hydroperoxide compound (a2); and at least one cyclic thiourea compound (a3) selected from the group consisting of a substituted ethylenethiourea compound (a3-1), a substituted propylenethiourea compound (a3-2), and a substituted butylenethiourea compound (a3-3) each having a specific structure with a cyclic structure moiety into which a substituent is introduced.Type: GrantFiled: March 19, 2014Date of Patent: February 13, 2018Assignee: KURARAY NORITAKE DENTAL INC.Inventors: Nobusuke Kashiki, Kenji Suzuki
-
Patent number: 9889071Abstract: The present invention discloses a new family of calcium sulfate resin-modified hybrid (CSRH) materials and methods of making and using the same.Type: GrantFiled: March 14, 2014Date of Patent: February 13, 2018Assignee: The Regents of the University of CaliforniaInventors: Shane White, Adam Inaba
-
Patent number: 9889072Abstract: A porous silica particle with the small specific surface area and large pore volume, which is contained as the scrubbing agent in the cleansing cosmetics is provided. The porous silica particle has high collapsibility, and therefore the damage of the skin can be prevented. A porous silica particle according to the present invention has: an average circularity of 0.1 to 0.5; a pore volume of 0.1?Pv<1.0 ml/g; a specific surface area of 5 to 60 m2/cm3; a median size of 100 to 1000 ?m; a ratio of a maximum particle diameter to the median size, of 3.0 or less; and a median size of 5 to 40 ?m and a maximum particle diameter of 15 to 200 ?m, after rubbing for 30 seconds with a load of 1.0 to 1.4 KPa.Type: GrantFiled: October 2, 2015Date of Patent: February 13, 2018Assignee: JGC CATALYSTS AND CHEMICALS LTD.Inventors: Satoshi Watanabe, Naoyuki Enomoto, Yasutaka Miyoshi
-
Patent number: 9889073Abstract: The instant invention relates to a color changing composition in the form of an emulsion comprising, at least: a) microcapsules containing releasable colorant(s), said microcapsules comprising: —a core comprising one organic material, —at least one layered coating surrounding said core, the layered coating comprising at least one polymer, at least one colorant, and advantageously at least one lipid-based material, b) at least partially neutralized, crosslinked acrylic homopolymers or copolymers preferably in a non-particulate form.Type: GrantFiled: March 5, 2014Date of Patent: February 13, 2018Assignee: L'OREALInventors: Audrey Ricard, Micheline El Achkar
-
Patent number: 9889074Abstract: Notch filter coatings for use in sunscreen applications are provided herein. An exemplary composition includes multiple zinc oxide particles suspended within a medium forming sunscreen composition; and a combination of multiple notch filter coating materials individually applied as a distinct layer to each of the multiple zinc oxide particles to create a multi-layered structure surrounding each of the multiple zinc oxide particles within the sunscreen composition, wherein the multi-layered structure: reflects light at a user-determined wavelength range based on the wavelength range at which each of the multiple notch filter coating materials reflects light; and allows wavelengths of light (i) within at least a portion of the ultraviolet spectrum and (ii) outside of the user-determined wavelength range to be absorbed by the multiple zinc oxide particles.Type: GrantFiled: March 3, 2017Date of Patent: February 13, 2018Assignee: International Business Machines CorporationInventors: Talia S. Gershon, Ning Li, Devendra Sadana, Teodor K. Todorov
-
Patent number: 9889075Abstract: Cleaning composition, which is a dry shampoo, comprising a base and propellant, wherein the base comprises sebum absorber which comprises magnetic particles, wherein the magnetic particles have a particle size in the range of from 4 nm to 50 nm, and wherein the magnetic particles are coated with a stabilizing dispersing agent, and wherein the magnetic particles are dispersed in a liquid carrier.Type: GrantFiled: October 22, 2014Date of Patent: February 13, 2018Assignee: Conopco, Inc.Inventors: Nicholas Ballard, Stefan Antonius Franciscus Bon, Ezat Khoshdel, Glyn Roberts
-
Patent number: 9889076Abstract: A preparation provides light or radiation attenuation between about 190 and 800 nm has an amount of diamond nanoparticles in a medium, where the diamond nanoparticles have a size between about 1 nm and 1000 nm are modified to enhance absorption or photoluminescence. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.Type: GrantFiled: February 11, 2016Date of Patent: February 13, 2018Assignees: Adámas Nanotechnologies, Inc., International Technology CenterInventors: Olga Alexander Shenderova, Varvara Grichko
-
Patent number: 9889077Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.Type: GrantFiled: October 30, 2014Date of Patent: February 13, 2018Assignee: Colgate-Palmolive CompanyInventors: Lyndsay Schaeffer-Korbylo, Andre Michelle Morgan, Davide Miksa, Laurence Du-Thumm, Michael Prencipe, Evangelia Arvanitidou, Gregory Szewczyk
-
Patent number: 9889078Abstract: Suggested is a skin or hair whitening mixture, comprising (a) resorcinol derivatives of formula (I) in which R stands for an alkyl radical having 3 to 10 carbon atoms or an optionally substituted alkylphenyl radical having 8 to 16 carbon atoms, and (b) bisabolol, and optionally (c) alkandiols having 3 to 10 carbon atoms.Type: GrantFiled: August 28, 2014Date of Patent: February 13, 2018Assignee: Symrise AGInventors: Imke Meyer, Gabriele Vielhaber, Aurélie Trunet, Mareille Le Maire
-
Patent number: 9889079Abstract: Process for making a conditioning gel phase comprising: i) forming an aqueous dispersion of fatty alcohol and amidoamine; ii) adding a cationic surfactant to the aqueous dispersion and mixing; and iii) neutralizing the amidoamine, wherein the temperature of the mixture of cationic surfactant in the aqueous dispersion is maintained at from 56° C. to 67° C.Type: GrantFiled: July 24, 2013Date of Patent: February 13, 2018Assignee: Conopco, Inc.Inventors: Christia Casugbo, Mark Flanagan, John Alan Hough, John Michael Naughton, David Serridge
-
Patent number: 9889080Abstract: A composition for coloring and shampooing hair substantially free, preferably totally and completely free, of anionic surfactants, comprising at least one cationic dye, n-methyl alkyl glucamide with a carbon chain length from 8 and 20, inclusive, preferably 8 and 10, an aqueous carrier, and at least one stabilizer of anti-oxidant and free radical scavanger. By weight, (based on the total weight of the composition), the composition comprises 0.0005% to 3.0% cationic dye, 2.5 to 30% n-methyl alkyl glucamide, 30 to 70% water, and 0.01 to 0.5% stabilizers of anti-oxidant and free radical scavenger. Other ingredients, including a rheology modifying polymer, conditioning ingredients, and additional surfactants, may also be included in the composition and are also included in the scope of the invention.Type: GrantFiled: April 27, 2016Date of Patent: February 13, 2018Assignee: Celeb LLCInventors: Cindy Orr, Lauren LaBeaud, Leland Hirsch
-
Patent number: 9889081Abstract: The present invention provides methods and compositions for reducing pigmentation.Type: GrantFiled: July 2, 2014Date of Patent: February 13, 2018Assignees: The Regents of the University of California, Board Of Regents, The University Of Texas SystemInventors: Anand Ganesan, Michael A. White, Patrick J. Farmer
-
Patent number: 9889082Abstract: This invention provides methods of treating androgenetic alopecia (AGA), acne, rosacea, prostate cancer, and benign prostatic hypertrophy (BPH), comprising the step of contacting a subject with a compound or composition capable of decreasing prostaglandin D2 (PGD2) level or activity, a downstream signaling or receptor pathway thereof, or prostaglandin D2 synthase level or activity; methods of stimulating hair growth, comprising the step of contacting a subject with a compound or composition capable of increasing or decreasing the activity or level of a target gene of the present invention, or with a protein product of the target gene or an analog or mimetic thereof; and methods of testing for AGA and evaluating therapeutic methods thereof, comprising measuring PGD2 levels.Type: GrantFiled: August 24, 2015Date of Patent: February 13, 2018Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAInventors: George Cotsarelis, Luis Garza
-
Patent number: 9889083Abstract: The present invention provides a two-part hair cosmetic material having a reduced irritating smell due to ammonia. Specifically, the present invention relates to a two-part hair cosmetic material comprising a first agent containing an alkali agent and a second agent containing an oxidizing agent, wherein the first agent contains the following ingredients: (A) a polyoxyethylene alkyl ether having a polyoxyethylene chain length of 50 or more, (B) a higher alcohol, and (C) a polyoxyethylene alkyl ether having a polyoxyethylene chain length shorter than the polyoxyethylene chain length of the polyoxyethylene alkyl ether (A), and the content of a higher alcohol having 20 or more carbon atoms in the higher alcohol (B) is 1.0% by weight or less based on the weight of the first agent.Type: GrantFiled: April 29, 2015Date of Patent: February 13, 2018Assignee: Henkel AG & Co. KGaAInventors: Fumika Ikeno, Masaki Kawai, Shoji Machida, Kota Uchida, Akira Matsutani, Maki Miyamoto
-
Patent number: 9889084Abstract: Lipid compositions and lipid compositions included in cosmetic products, personal care products, skin care products, nutraceuticals, bio fuels, bio-lubricants, oleo chemicals, nutritional products, other bio-products, and animal feed compositions. Concentrations of lipid components. A method of removing and recovering a lipid composition by mixing a lipid feedstock with a solvent, separating the mixture into a raffinate phase and an extract phase containing beneficial non-glyceride compounds, removing solvent from the extract phase and obtaining a concentrate phase, and recovering a lipid composition from the concentrate phase. A method of producing a fatty acid alkyl ester. A method of producing a distiller's product.Type: GrantFiled: January 12, 2015Date of Patent: February 13, 2018Assignee: Valicor, Inc.Inventors: James Robert Bleyer, Jennifer L. Aurandt, Raymond Paul Roach
-
Patent number: 9889085Abstract: The present invention is directed to treatments for a disease or condition, in a subject in need thereof, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is achieved within about 7 days after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using insulinotrophic peptides. In embodiments, a subject has a baseline HbA1c % of greater than 6.5% or 10.0%.Type: GrantFiled: September 30, 2015Date of Patent: February 13, 2018Assignee: INTARCIA THERAPEUTICS, INC.Inventors: Thomas R. Alessi, Michelle Baron
-
Patent number: 9889086Abstract: The present invention provides a novel hydrogel, methods of its use, and methods for producing the hydrogel.Type: GrantFiled: February 2, 2016Date of Patent: February 13, 2018Assignee: The Chinese University of Hong KongInventors: Liming Bian, Qian Feng, Kongchang Wei, Gang Li, Sien Lin
-
Patent number: 9889087Abstract: A method of improving cognition in a patient with Down syndrome, which entails intranasally administering one or more ?2-ADR agonists or pharmaceutically-acceptable salts of either or both to the patient in an amount and with a frequency effective to improve cognition of the patient as measured contextual learning tests.Type: GrantFiled: May 26, 2015Date of Patent: February 13, 2018Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ahmad Salehi, Brian Medina, Van Dang, Devsmita Das
-
Patent number: 9889088Abstract: The present invention provides a method of lowering intraocular pressure which comprises administering a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin-2-ylamino)benzimidazole, or a salt thereof to the affected eye of a patient, as a single dose, wherein the affected eye has an intraocular pressure less than the baseline intraocular pressure for at least eight (8) hours.Type: GrantFiled: January 21, 2011Date of Patent: February 13, 2018Assignee: Allergan, Inc.Inventors: Mohammed I. Dibas, Daniel W. Gil, John E. Donello
-
Patent number: 9889089Abstract: Provided herein is a storage stable non-fluoride toothpaste composition enriched with a dietary supplement containing both oil soluble and water soluble vitamins. The dietary supplement is incorporated into the toothpaste, the dietary supplement containing a water soluble vitamin portion including at least one water soluble vitamin and an oil soluble vitamin portion. The oil soluble vitamin portion includes at least one oil soluble vitamin, a carrier oil and an emulsifier. The toothpaste is thereby formulated in a manner such that oral application will result in systemic delivery of at least a portion of the dietary supplement to meet a 2% RDI threshold even when 3 or less serving sizes are orally applied.Type: GrantFiled: April 4, 2016Date of Patent: February 13, 2018Assignee: Golden Products LLCInventor: Bruce Alan Golden
-
Patent number: 9889090Abstract: A method for treating a periodontal disease affecting a periodontal pocket of a patient. The method comprises inserting an oral delivery device into the periodontal pocket at a frequency of about once every 4 days to about once every 6 weeks. The oral delivery device is a controlled release solid unit dosage form suitable for insertion into a periodontal pocket of a patient, comprising a therapeutically effective amount of at least one anti-inflammatory agent, at least one antibacterial agent, or the combination of at least one anti-inflammatory agent and at least one antibacterial agent.Type: GrantFiled: February 17, 2016Date of Patent: February 13, 2018Assignee: Dexcel Pharma Technologies Ltd.Inventors: Avi Avramoff, Eyal Shoshani, Adel Penhasi, Dan Oren
-
Patent number: 9889091Abstract: A unit to treat inflammation of hemorrhoids, vulvo-vaginitis and similar conditions has a suppository and a multi-piece pad at a proximal end of the suppository. A first piece of the pad is adjacent the suppository so that medication can be applied concurrently to both. A second piece of the pad is a non-permeable layer disposed against the first piece. A third piece is an absorbent layer disposed against the second piece. A fourth piece is another non permeable layer disposed against the third piece. Medication from a container is applied to the unit through an adapter.Type: GrantFiled: August 13, 2011Date of Patent: February 13, 2018Inventor: Yousef Daneshvar
-
Patent number: 9889092Abstract: An LDL nanocarrier is an effective and appropriate transporter for DHA in biological systems. The LDL-DHA nanoparticle was shown to be preferentially cytotoxic to malignant liver cells. These LDL-DHA nanoparticles show great promise as an anti-cancer agent. In particular embodiments, the nanoparticles exhibit a diameter of 15 to 30 nm.Type: GrantFiled: March 13, 2014Date of Patent: February 13, 2018Assignee: The Board of Regents of the University of Texas SystemInventor: Ian R. Corbin
-
Patent number: 9889093Abstract: The present invention relates to an andrographolide enteric targeting micropellet and a method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in preparation of a pharmaceutical for treatment of inflammatory bowel disease.Type: GrantFiled: August 6, 2014Date of Patent: February 13, 2018Assignee: Tasly Pharmaceutical Group Co., Ltd.Inventors: Henry Sun, Xiaohui Ma, Zhixin Guo, Sen Lin, Genbei Wang, Lulu Yan, Lihua Zhang, Shuiping Zhou, Shunnan Zhang
-
Patent number: 9889094Abstract: A stable crystalline micronized particulate of a glycopyrronium salt may be prepared by suspending the drug in a water-immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.Type: GrantFiled: June 10, 2016Date of Patent: February 13, 2018Assignee: CHIESI FARMACEUTICI S.p.A.Inventors: Irene Pasquali, Andrea Casazza, Elena Losi, Mark Saunders
-
Patent number: 9889095Abstract: Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of active drug in a delayed and controlled release formulation. The dosage form can be administered at night and drug release is delayed for from 5 to 8 hours or longer, followed by a prolonged release.Type: GrantFiled: March 27, 2017Date of Patent: February 13, 2018Assignee: Ironshore Pharmaceuticals & Development, Inc.Inventors: David Lickrish, Feng Zhang
-
Patent number: 9889096Abstract: The present invention is directed to compositions and methods of delivery of CoQ that is reduced in the presence of lipoic acid and, optionally a fatty acid and/or optionally in a monoterpene. The compositions that include the reduced CoQ can be formulated in soft gel capsules.Type: GrantFiled: May 20, 2016Date of Patent: February 13, 2018Assignee: Soft Gel Technologies, Inc.Inventor: Michael Fantuzzi
-
Patent number: 9889097Abstract: The invention relates to a novel powder, it's method of manufacture and the use thereof in powder material processing, particularly in the manufacture of components formed from compacted powder e.g. discs, monoliths, layers or tablets. The powders comprise coated host particles wherein over 70% of the mass of the powder comprises coated particles smaller than 100 microns. The powders have particular application in the pharmaceutical industry and the technology described can be used to control the properties of active pharmaceutical ingredients. The powders (10) may comprise drug particles (12), carrier particles (14) and additives (16).Type: GrantFiled: June 19, 2008Date of Patent: February 13, 2018Assignee: NANO4M LIMITEDInventor: David Morton
-
Patent number: 9889098Abstract: The subject invention relates to novel micoparticulate and soluble forms of flavonoids, and their synthesis. The invention also includes novel formulations of such flavonoids. Further, the invention includes novel methods of manufacturing the flavonoid formulations. The invention also relates to a wide variety of applications of the flavonoid formulations.Type: GrantFiled: October 22, 2010Date of Patent: February 13, 2018Assignee: VIZURI HEALTH SCIENCES LLCInventor: Philip J. Birbara
-
Patent number: 9889099Abstract: The present invention concerns a method of enhancing milk production by a ruminant that includes providing a feed that contains sorbitol and at least one additional feed component, and orally feeding the feed to the ruminant, the ruminant ingesting about 100 grams, or less, of sorbitol per day.Type: GrantFiled: May 2, 2017Date of Patent: February 13, 2018Assignee: LAND O'LAKES, INC.Inventor: Cindie M. Luhman
-
Patent number: 9889100Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.Type: GrantFiled: May 2, 2016Date of Patent: February 13, 2018Assignee: MOR RESEARCH APPLICATIONS LTD.Inventor: Moshe Yeshurun
-
Patent number: 9889101Abstract: A method for treatment of cervical or vaginal cancer and their associated dysplasia, including the steps of identifying a human cervical or vaginal cancer and/or dysplasia patient, administering an effective amount of an estrogen antagonist therapy to the patient, wherein the amount is effective to reduce cancer and dysplasia symptoms, and observing a reduction of cancer and dysplasia symptoms in the patient.Type: GrantFiled: March 12, 2012Date of Patent: February 13, 2018Assignee: Wisconsin Alumni Research FoundationInventors: Paul F. Lambert, SangHyuk Chung