Patents Issued in March 8, 2018
  • Publication number: 20180067120
    Abstract: Markers useful for the identification, characterization and, optionally, the enrichment or isolation of tumorigenic cells or cell subpopulations are disclosed.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 8, 2018
    Applicant: ABBVIE STEMCENTRX LLC
    Inventors: SCOTT J. DYLLA, MARIANNE SANTAGUIDA, WADE C. ANDERSON, BOB Y. LIU, SAMUEL A. WILLIAMS
  • Publication number: 20180067121
    Abstract: The present disclosure relates to a plurality of quantum dot nanoparticles conjugated to ligands, and in particular a plurality of quantum dot nanoparticles wherein each nanoparticle is conjugated to an exosome-specific binding ligand. The present disclosure also relates to methods of making such a plurality of conjugated quantum dot nanoparticles, methods of detecting exosomes using such a plurality of conjugated quantum dot nanoparticles and methods of detecting exosomes using such a plurality of conjugated quantum dot nanoparticles.
    Type: Application
    Filed: September 5, 2017
    Publication date: March 8, 2018
    Inventor: Imad Naasani
  • Publication number: 20180067122
    Abstract: The invention relates to a Model Gut System (MGS) comprising a pancreatic phase consisting essentially of synthetic pancreatic juice comprising pancreatin and one or more suitable pancreatic diluent(s) at a pH from about 7 to about 9, preferably about 7.9 to about 8.2, and porcine bile.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 8, 2018
    Applicant: University of Newcastle Upon Tyne
    Inventors: Jeff Pearson, Iain Brownlee, Matt Wilcox, Peter Chater
  • Publication number: 20180067123
    Abstract: A protein assay method, including: 1) dissolving 4-hydroxybenzenesulfonic acid in an ethanol, methanol, or acetonitrile aqueous solution to prepare a hydrolysis reagent, adding a protein sample and the hydrolysis reagent to a hydrolysis tube, and uniformly mixing the protein sample and the hydrolysis reagent, charging argon or nitrogen into the hydrolysis tube to remove dissolved oxygen, sealing and drying the hydrolysis tube, and hydrolyzing the protein sample; 2) cooling the hydrolysis tube to room temperature, filtering and adding a resulting hydrolysate to a volumetric flask, washing the hydrolysis tube and a filter paper, collecting and adding a resulting washing solution to the volumetric flask to a constant volume; 3) drawing a hydrolysate solution from the volumetric flask, completely drying the hydrolysate solution to yield a solid product; and 4) diluting the solid product using a diluent, and analyzing amino acids of the solid product.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 8, 2018
    Inventors: Hongxia LI, Yuhan LUO, Fuyuan CAO, Huiyi ZHANG, Jinshan HU, Junjie ZHANG
  • Publication number: 20180067124
    Abstract: The present invention uses anthranilic acid (2-AA) to label N-glycans prior to separation using a reversed-phase liquid chromatography (RP-LC) column under acidic conditions using formic acid. Negatively charged 2-AA offers stronger retention on the reversed phase column than 2-aminobenzamide (2-AB) in RP-LC and allows efficient ionization and detection of 2-AA labeled N-glycans. The acidic conditions used for the RP-LC leads to an efficient separation of acidic 2-AA N-glycans carrying terminal sialylation without the need for an ion-pairing reagent. The present invention may be used with RP-nano-LC-MS and a 96-well plate sample preparation, which allows attomolar sensitivity and high throughput.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 8, 2018
    Inventors: Fabian HIGEL, Andreas SEIDL
  • Publication number: 20180067125
    Abstract: The present invention provides a method of diagnosing type 1 diabetes (T1D) or latent autoimmune diabetes in adults (LADA) in a subject comprising testing a sample from the subject for the presence or absence of antibodies against modified insulin, wherein the presence of antibodies against modified insulin in the sample is indicative of T1D or LADA in the subject. The invention also provides a method of treating T1D or LADA in a subject in need thereof. Also provided are methods of determining the 10 therapeutic effectiveness of a therapeutic agent in treating T1D or LADA in a subject diagnosed with T1D or LADA. A kit for diagnosing T1D or LADA in a subject comprising reagents for determining the presence of antibodies against modified insulin in a sample from a subject is also provided.
    Type: Application
    Filed: March 11, 2016
    Publication date: March 8, 2018
    Inventors: Ahuva Nissim, Paolo Pozzilli, Rocky Strollo
  • Publication number: 20180067126
    Abstract: The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases.
    Type: Application
    Filed: November 17, 2017
    Publication date: March 8, 2018
    Inventors: Jan Steyaert, Els Pardon, Soren G.F. Rasmussen, Juan Jose Fung, Brian Kobilka, Toon Laeremans
  • Publication number: 20180067127
    Abstract: A method of detecting the presence, or monitoring the severity of a condition characterised by the presence of fragments of a marker protein in the brain of a patient. The method comprises: (i) providing a sample comprising macrophages obtained from the patient; and (ii) detecting the presence of the marker protein or fragments thereof in the macrophages. The presence of abnormal levels of the marker protein and/or fragments thereof in the macrophages is indicative of the presence of the condition in the patient. The condition and the marker proteins can be: Alzheimer's Disease and the Abeta peptide, Parkinson's Disease and ubiquitin, Multiple Sclerosis and myelin basic protein, FrontoTemporal Dementia and tau, Amyotrophic Lateral Sclerosis and tau, Parkinson's disease, Lewy Body dementia or Alzheimer's Disease and alpha-synuclein.
    Type: Application
    Filed: March 30, 2017
    Publication date: March 8, 2018
    Applicant: INVEN2 AS
    Inventors: Tormod Fladby, Lisbeth Johnsen, Kaj Blennow
  • Publication number: 20180067128
    Abstract: The invention relates to the field of the diagnosis and prognosis methods of molecular pathologies. In particular, the invention relates to methods for determining the diagnosis of an ectatic disease of the cornea in a subject, for determining the risk of developing an ectatic disease of the cornea in a subject, for determining the clinical outcome of a subject suffering from an ectatic disease of the cornea and for selecting a subject to be treated with a therapy for an ectatic disease of the cornea based on the determination of the expression levels of TLR2 and/or TLR4 markers. The invention also relates to the use of the TLR2 and/or TLR4 as diagnosis and prognosis markers for an ectatic disease of the cornea.
    Type: Application
    Filed: February 16, 2016
    Publication date: March 8, 2018
    Inventors: María Isabel Lema Gesto, José Antonio Castillo Sánchez, Tomás Sobrino Moreiras, Francisco Campos Perez
  • Publication number: 20180067129
    Abstract: This invention provides reagents, methods and biochemical markers for identifying and providing therapeutic intervention for individuals with metabolic dysfunction, or individuals at risk for metabolic dysfunction.
    Type: Application
    Filed: March 17, 2016
    Publication date: March 8, 2018
    Inventors: John F. RAWLS, James MINCHIN
  • Publication number: 20180067130
    Abstract: A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the subject has received the tissue transplant determining in the biological sample a level of at least one protein selected from Tables 1-4, comparing the measured level of the at least one protein to a control value, and characterizing a subject as at greater risk of developing an autoimmune disease and/or alloimmune disease if the level of at least one protein determined is increased or decreased compared to the control value.
    Type: Application
    Filed: November 7, 2017
    Publication date: March 8, 2018
    Inventors: Mark Chance, Kenneth Cooke, Daniela Schlatzer
  • Publication number: 20180067131
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Proheparin-binding EGF-like growth factor, Tenascin C, Angiopoietin-related protein 4, Fibroblast growth factor 19, Fibroblast growth factor 21, Heparin-binding growth factor 1, Angiopoietin-related protein 6, Proepiregulin, Probetacellulin, Amphiregulin, Angiogenin, Thrombospondin-2, and Collagen alpha-1(XVIII) chain as diagnostic and prognostic biomarkers in renal injuries.
    Type: Application
    Filed: November 20, 2017
    Publication date: March 8, 2018
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Publication number: 20180067132
    Abstract: Disclosed is a method for assisting the detection of Alzheimer's disease or mild cognitive impairment, the method for assisting the highly accurate detection of Alzheimer's disease or mild cognitive impairment. In the method for assisting the detection of Alzheimer's disease or mild cognitive impairment, the amount of at least one miRNA selected from miR-122, miR-144, let-7f, miR-128-3p and miR-107 contained in a test sample separated from a living body is used as an indicator. A larger amount of miR-122 than that in a healthy individual, or a smaller amount of at least one miRNA selected from miR-144, let-7f, miR-128-3p and miR-107 than that in a healthy individual is indicative that the living body is more likely to have developed Alzheimer's disease or mild cognitive impairment.
    Type: Application
    Filed: March 11, 2016
    Publication date: March 8, 2018
    Applicant: HIROSHIMA UNIVERSITY
    Inventors: Hidetoshi TAHARA, Masayasu MATSUMOTO, Yu NINOSE
  • Publication number: 20180067133
    Abstract: Alzheimer's disease (AD) is the most common type of dementia in aging adults with the number of people living with AD projected to increase, making the search for treatments and tools to diagnose and measure disease progression increasingly urgent. In particular, ideal biomarkers for diagnosis of AD should not only have high specificity for disease versus non-disease and high sensitivity for distinguishing between disease types but also should be able to detect changes at a very early stage of the disease. Using microglia activation as an early event of AD's onset, the present inventors have identified a panel of biomarkers in CSF which has the potential to diagnose, stage and determine the likelihood of developing AD.
    Type: Application
    Filed: March 17, 2016
    Publication date: March 8, 2018
    Applicant: ELECTROPHORETICS LIMITED
    Inventors: Ian Hugo PIKE, Claire Louise RUSSELL, Malcolm WARD
  • Publication number: 20180067134
    Abstract: The present description relates to methods for clinically assessing Parkinson's disease in a subject using erythrocyte-derived extracellular vesicles (EEV) as a biomarker.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 8, 2018
    Inventors: Francesca Cicchetti, Eric Boilard, Steve Lacroix, Isabelle St-Amour
  • Publication number: 20180067135
    Abstract: This invention relates to the measurement of hemoglobin in the blood. Previously, chemical interference from medications, other blood components, and incomplete reagent rehydration can impact the accuracy and prolong the reaction time required to determine total hemoglobin in blood. Embodiments of the present invention use a disposable body is housed within the capillary channel and adapted to receive a flow of blood from the entrance such that air in the disposable body is pushed out through a vent. A measurement system is configured to measure a property of the flow of blood. That property can be correlated to total hemoglobin count.
    Type: Application
    Filed: November 13, 2017
    Publication date: March 8, 2018
    Inventor: Emmanuel Chuyuk Mpock
  • Publication number: 20180067136
    Abstract: The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X?xY?xZ. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumour/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumour/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumour with radiation.
    Type: Application
    Filed: September 27, 2017
    Publication date: March 8, 2018
    Inventor: George L. Gabor Miklos
  • Publication number: 20180067137
    Abstract: Disclosed herein are compositions and methods for targeted metabolomics profiling to provide absolute quantification of a broad array of metabolic intermediates of fatty acids, amino acids, and carbohydrate metabolism for HFpEF. In an aspect, the disclosure relates to a method for assessing risk of death or a major adverse cardiac event (MACE) in a subject diagnosed with heart failure with preserved ejection fraction (HFpEF). The method may include (a) determining in a sample from the subject the level of each metabolite in at least one factor, wherein the factor is selected from the group consisting of factor 1, factor 3, factor 4, factor 5, factor 10, factor 12, and factor 14; and (b) comparing the level of each metabolite in the sample to a standard, wherein the level of the metabolite in the subject relative to a standard is indicative of the risk of death or MACE in the subject.
    Type: Application
    Filed: March 14, 2016
    Publication date: March 8, 2018
    Applicant: Duke University
    Inventor: Svati Shah
  • Publication number: 20180067138
    Abstract: The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided is an antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications.
    Type: Application
    Filed: November 3, 2017
    Publication date: March 8, 2018
    Inventors: Reijo Laaksonen, Kim Ekroos, Reini Hurme, Riikka Katainen
  • Publication number: 20180067139
    Abstract: An automated system and method for storing/retrieving vessel holders is presented. A first storage compartment comprises first storage sections. A first translating mechanism vertically translates one storage section to a loading level for loading holders into the first storage compartment and translates one storage section to a handing-in level for handing in holders to/from an analyzer. A second storage compartment comprises second storage sections. A second translating mechanism vertically translates one second storage sections to a handing-out level and translates one storage section to an unloading level for unloading holders from the second storage compartment. A first transport mechanism comprises a first conveyor for transporting holders from a first storage section at the handing-in level to a handing-over station. A second transport mechanism comprises a second conveyor for transporting holders from the handing-over station to a second storage section at the handing-out level.
    Type: Application
    Filed: November 9, 2017
    Publication date: March 8, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Martin Burri, Andreas Eberhart, Akihiro Tanji
  • Publication number: 20180067140
    Abstract: A method for determining a background shift is presented. The method includes obtaining a plurality of optical measurement sets of a sample taken by a sample analyzer at different points in time. Each set includes one measurement taken in a first channel and another measurement taken in a second channel different from the first channel. The plurality of optical measurement sets includes one set group and another set group. The measurements in the one set group show a higher signal change than the measurements in the other group. A first background signal is determined based on a relation of measurements in the first and second channels in the one group. A second background signal is determined based on a relation of measurements in the first and second channels in the one group and the other group. A background shift is determined based on the first and second background signals.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 8, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventor: Rolf Knobel
  • Publication number: 20180067141
    Abstract: A method of operating a laboratory sample distribution system is presented. The laboratory sample distribution system comprises a number of sample container carriers. The sample container carriers are adapted to carry one or more sample containers. The sample containers comprise samples to be analyzed by a number of laboratory stations. The laboratory sample distribution system also comprises a transport plane. The transport plane is adapted to support the sample container carriers. The method comprises allocating an area of the transport plane as a buffer area. The buffer area is adapted to store a variable number of sample container carriers. The method also comprises controlling the buffer area using a puzzle-based control scheme or using an aisle-based control scheme as a function of a storage density of the buffer area.
    Type: Application
    Filed: November 10, 2017
    Publication date: March 8, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Mohammadreza Mahmudimanesh, Sophia Bruntsch, Soraya Garcia Bustos, Walter Ebner, Shubin Ren, Mohsin Reza, Daniel Diez Diaz-Calonge
  • Publication number: 20180067142
    Abstract: Means and methods for dispensing small amounts of liquid from multi-channel microdispensing devices, suitable for use in automatic processing in biological assays and for the cultivation of cells and tissues, by means of optical control of the dosed liquid by specific light barrier units.
    Type: Application
    Filed: August 10, 2017
    Publication date: March 8, 2018
    Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG e.V.
    Inventors: Michael KLINGER, Christopher LASKE
  • Publication number: 20180067143
    Abstract: A sensor comprises a substrate having a first surface; a cap structure connected to the substrate, the cap structure configured to define a cavity between an inner surface of the cap structure and the first surface of the substrate, the cap structure configured to block infrared radiation from entering the cavity from outside the cap structure; a plurality of absorbers, each absorber in the plurality of absorbers being connected to the first surface of the substrate and arranged at a respective position within the cavity and configured to absorb infrared radiation at the respective position within the cavity; and a plurality of readout circuits, each readout circuit in the plurality of readout circuits being connected to a respective absorber in the plurality of absorbers and configured to provide a measurement signal that indicates an amount of infrared radiation absorbed by the respective absorber.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 8, 2018
    Applicant: Robert Bosch GmbH
    Inventors: Seow Yuen Yee, Gary Yama, Thomas Rocznik
  • Publication number: 20180067144
    Abstract: A functional device includes a fixed electrode portion including a first fixed electrode portion and a second fixed electrode portion, a first wiring portion connected to the first fixed electrode portion, and a second wiring portion connected to the second fixed electrode portion. At least one of the first wiring portion and the second wiring portion is provided with a branch portion. One wiring line extending from the branch portion is connected to the fixed electrode portion, and another wiring line extending from the branch portion is provided along the first wiring portion or the second wiring portion.
    Type: Application
    Filed: November 1, 2017
    Publication date: March 8, 2018
    Inventor: Satoru TANAKA
  • Publication number: 20180067145
    Abstract: A contact for use in a test set which can be mounted to a load board of a tester apparatus. The contact, which serves to electrically connect at least one lead of a device being tested with a corresponding metallic trace on the load board, has a first end defining multiple contact points. As the test pin is rotated about an axis generally perpendicular to a plane defined by the contact, successive contact points are sequentially engaged by a lead of the device being tested. The test pin has a hard stop edge which engages a hard stop wall which limits its rotation movement. The bottom of the pin has a shallow convex curvature preferably with a flat region and the tip of the test pin has a chisel edge.
    Type: Application
    Filed: October 27, 2017
    Publication date: March 8, 2018
    Inventor: Michael Andres
  • Publication number: 20180067146
    Abstract: An electric current sensor includes a primary conductor through which an electric current to be measured flows, and at least one magnetic sensor. The magnetic sensor includes a first magnetic sensor area, the output sensitivity of which is decreased when a magnetic field is applied to include a magnetic field component in a first direction along a sensitivity variation axis, and a second magnetic sensor area, the output sensitivity of which is increased when the magnetic field is applied to include a magnetic field component in a second direction that is opposite to the first direction.
    Type: Application
    Filed: October 27, 2017
    Publication date: March 8, 2018
    Inventor: Takashi KAWANAMI
  • Publication number: 20180067147
    Abstract: In order to measure a voltage, an electro-optic element is placed in an electrical field generated by the voltage, and light is passed from a light source through a Faraday rotator and the electro-optic element onto a reflector and from there back through the electro-optic element and the Faraday rotator, thereby generating a voltage-dependent phase shift between two polarizations of the light. The interference contrast as well as a principal value of the total phase shift between said polarizations are measured and converted to a complex value having an absolute value equal to the contrast and a phase equal to the principal value. This complex value is offset and scaled using calibration values in order to calculate a compensated complex value. The voltage is derived from the compensated complex value.
    Type: Application
    Filed: September 5, 2017
    Publication date: March 8, 2018
    Inventors: XUN GU, Klaus Bohnert, Sergio Vincenzo Marchese
  • Publication number: 20180067148
    Abstract: A current detection circuit includes: a resistor in a current path; first and second signal transmission units that transmit signals of first and second terminal sides of the resistor; a first difference operation unit that executes a difference operation on the signals transmitted by the first and second signal transmission units; a noise-capturing transmission unit starting point; third and fourth signal transmission units connected with the noise-capturing transmission unit starting point; a second difference operation unit that executes a difference operation on the signals transmitted by the third and fourth signal transmission units; and a summing operation unit that executes a summing operation on the first and second difference signals, wherein the first signal transmission unit and the fourth signal transmission unit are disposed close to each other and the second signal transmission unit and the third signal transmission unit are disposed close to each other.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 8, 2018
    Applicant: FANUC CORPORATION
    Inventors: Kunio TSUCHIDA, Taku SASAKI, Kiichi INABA
  • Publication number: 20180067149
    Abstract: Disclosed is a control line diagnostic apparatus for diagnosing a control line of a driver circuit in which a driven load is driven due to a current flowing through the control line from a first high-potential node to a first low-potential node when a driving switch having a higher potential than a potential of the driven load is turned on, the control line diagnostic apparatus including a first diagnostic line having an end connected to a first node provided on the control line and the other end connected to a second high-potential node, and including a first resistor, a second resistor, and a first diode connected to one another in series, a second diagnostic line having an end connected to the first node and the other end connected to a second low-potential node, and including a third resistor, a voltage measurement unit configured to measure a voltage of a second node provided between the first and second resistors, and a control unit configured to set predetermined operation modes by controlling the driv
    Type: Application
    Filed: July 1, 2016
    Publication date: March 8, 2018
    Applicant: LG CHEM, LTD.
    Inventors: Woo-Jung KIM, Tae-Youn KIM
  • Publication number: 20180067150
    Abstract: Adjustment of drive control based on a detection voltage of a transformer requires a loop time, and therefore high-speed processing of the adjustment is difficult. A semiconductor integrated circuit device includes a driving circuit that drives a power semiconductor device and a driving capability control circuit that controls a driving capability of the driving circuit. The driving circuit stops driving of the power semiconductor device based on an abnormal current detected from a sense current of the power semiconductor device. The driving capability control circuit controls the driving capability of the driving circuit based on a normal current detected from the sense current of the power semiconductor device.
    Type: Application
    Filed: October 30, 2017
    Publication date: March 8, 2018
    Applicant: Renesas Electronics Corporation
    Inventor: Makoto TSURUMARU
  • Publication number: 20180067151
    Abstract: Methods and systems provide for detecting tampering of a fuel dispenser. Power is applied to a valve coil of a fuel dispenser. The valve coil is part of a control valve configured to accomplish a gradated fuel flow of the fuel dispenser. Current flowing through the valve coil is measured in response to the power being applied to the valve coil. The current measurements are compared with predetermined criteria and tampering with the valve coil is determined if the current measurements are sufficiently different than expected.
    Type: Application
    Filed: November 13, 2017
    Publication date: March 8, 2018
    Inventors: Geoffrey A. Benton, Michael L. Jennings
  • Publication number: 20180067152
    Abstract: The present technology relates to a signal processing apparatus, a control method, an image pickup element, and an electronic appliance that achieve the suppression of an increase in electric power consumption. The signal processing apparatus may be configured to control an amount of electric current at a differential stage in a comparison unit that compares signal levels of a plurality of signals and reduce the amount of electric current for a period other than this comparison period. For example, the amount of electric current may be reduced by turning off part of a group of switches each capable of disconnecting a path of an electric current from an electric current source. In addition, for example, the amount of electric current may be reduced by causing a gate potential at the electric current source unit to decrease. The present technology can be applied to, for example, an image pickup element and an electronic appliance.
    Type: Application
    Filed: November 13, 2017
    Publication date: March 8, 2018
    Inventor: Tatsunori NAKAHARA
  • Publication number: 20180067153
    Abstract: In various embodiments, a method for processing a Single-Edge Nibble Transmission Signal is provided. The method includes determining of at least one drop in a signal level of the time-variable Single-Edge Nibble Transmission Signal and at least one next rise in the signal level after the drop in the signal level, determining a time interval between the drop and the next rise in the signal level, and determining a quality of the Single-Edge Nibble Transmission Signal by using the time interval.
    Type: Application
    Filed: September 1, 2017
    Publication date: March 8, 2018
    Inventors: Andreas Kolof, Dietmar Koenig
  • Publication number: 20180067154
    Abstract: Embodiments of synchronous detection circuits and methods are provided for extracting magnitude and phase information from a waveform. One embodiment of a synchronous detection circuit includes a driver circuit, an analog-to-digital converter (ADC) and a controller. The driver circuit is configured to supply an input waveform at an input frequency to a load. The ADC is coupled to receive an output waveform from the load, and configured for generating four digital samples, each spaced 90° apart, for every period of the output waveform. The controller is configured for setting an oversampling rate (OSR) of the ADC, so that the ADC generates an integer number, M, of sub-samples for each digital sample generated by the ADC, where the integer number, M, of sub-samples is inversely proportional to the input frequency of the input waveform. The controller is further configured to use the digital samples generated by the ADC to extract magnitude and phase information from the output waveform.
    Type: Application
    Filed: September 7, 2016
    Publication date: March 8, 2018
    Inventors: Alexander Cherkassky, Bruce P. Del Signore
  • Publication number: 20180067155
    Abstract: A capacitive sensor device comprises a first sensor electrode, a second sensor electrode, and a processing system coupled to the first sensor electrode and the second sensor electrode. The processing system is configured to acquire a first capacitive measurement by emitting and receiving a first electrical signal with the first sensor electrode. The processing system is configured to acquire a second capacitive measurement by emitting and receiving a second electrical signal, wherein one of the first and second sensor electrodes performs the emitting and the other of the first and second sensor electrodes performs the receiving, and wherein the first and second capacitive measurements are non-degenerate. The processing system is configured to determine positional information using the first and second capacitive measurements.
    Type: Application
    Filed: October 30, 2017
    Publication date: March 8, 2018
    Applicant: Synaptics Incorporated
    Inventors: Joseph Kurth REYNOLDS, Phillip Acker, JR., Kirk Hargreaves, Shahrooz Shahparnia
  • Publication number: 20180067156
    Abstract: Systems and methods of applying repeatable stress pulses to an integrated circuit device under test using the charged device model (CDM) test is provided. The CDM spark conduction using discharge pin implemented in sections allows the spark environment to be controlled increasing the stress reproducibility and ability to apply the CDM test to devices with fine pitch terminals.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 8, 2018
    Inventors: Roger Watkins, Evan Grund
  • Publication number: 20180067157
    Abstract: A method for detecting correct connection of at least one energy reservoir to a vehicle electrical system of a motor vehicle. The method includes: ascertaining a voltage dropping at the energy reservoir, and/or a current flowing through the energy reservoir, and/or a voltage present at a terminal as a representative of the electrical system voltage, when the electrical system voltage exceeds or falls below at least one desired voltage, preferably as a function of at least one magnitude characteristic of the energy reservoir, such as an open-circuit voltage or gassing voltage; comparing the ascertained magnitude, such as the voltage and/or current, with at least one limit value; correct connection of the energy reservoir to the vehicle electrical system, or at least one fault, is inferred as a function of the comparison.
    Type: Application
    Filed: February 29, 2016
    Publication date: March 8, 2018
    Inventors: Christian Bohne, Juergen Motz, Matthias Horn
  • Publication number: 20180067158
    Abstract: The present invention is to provide a voltage detecting device connected to an ungrounded high-voltage battery which is connected to a high-voltage conducting path becoming a charge and discharge path, the voltage detecting device detecting at least one of a ground fault of a system in which the high-voltage battery is arranged and a voltage of the high-voltage battery. The voltage detecting device has a magnetic switch in which ON/OFF is switched based on magnetic field generated by current flowing through the high-voltage conducting path. The magnetic switch switches between a first measuring condition and a second measuring condition different from the first measuring condition in a measuring circuit or a measuring parameter.
    Type: Application
    Filed: August 22, 2017
    Publication date: March 8, 2018
    Applicant: Yazaki Corporation
    Inventor: Yoshihiro KAWAMURA
  • Publication number: 20180067159
    Abstract: A device for verifying wire connectivity of a bus may include a bus connector configured to connect to a bus comprising a plurality of wires and measurement circuitry configured to perform a verification test on each wire of the bus. The verification test of each wire may include connecting a wire under test in a predetermined configuration relative to the other wires for performing the verification test and measuring a value of an electrical parameter associated with the wire under test. The verification test may also include comparing the value of the measured electrical parameter associated with the wire under test to an expected value of the electrical parameter. The wire under test passes the verification test in response to the measured value of the electrical parameter corresponding substantially to the expected value of the electrical parameter.
    Type: Application
    Filed: October 30, 2017
    Publication date: March 8, 2018
    Inventors: Sean M. Ramey, Jeffrey A. Lawrence, Enoch E. McDowell, John A. Sekora, Edgar L. von Trotha, III, David E. Lawrence
  • Publication number: 20180067160
    Abstract: Embodiments of the present disclosure describe wafer-level die testing devices having a base with a planar X-Y surface, a plurality of thermal actuators situated on the surface, wherein one or more of the plurality of thermal actuators is movable in relation to the base in at least one of the X or the Y directions, and one or more adjustable links, wherein each adjustable link is to adjust a relative position between an individual thermal actuator of the plurality of thermal actuators and one or more other thermal actuators of the plurality of thermal actuators in one or more of the X or the Y directions. Other embodiments may be described and/or claimed.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 8, 2018
    Inventor: Eric J.M. Moret
  • Publication number: 20180067161
    Abstract: A system that can include a computing device, upon implementing a host test program, can be configured to generate compiled host test instructions based on a non-host test program code that has been prepared in accordance with performance characteristics of a non-host automatic test equipment (ATE) and based on calibration data and/or offset data associated with a host ATE. The system can further include a hardware adapter that can be configured to generate non-host test signals based on host test signals generated by a host ATE and with substantially similar characteristics as test signals generated by the non-host ATE, wherein the host test signals are generated by the host ATE based on the compiled host test instructions.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 8, 2018
    Inventors: RAMANA TADEPALLI, ROBERT GABRIEL ALMENDAREZ
  • Publication number: 20180067162
    Abstract: Embodiments include methods, computer systems and computer program products for generating functional test patterns for diagnostics, characterization and manufacture test.
    Type: Application
    Filed: November 10, 2017
    Publication date: March 8, 2018
    Inventors: Franco Motika, John D. Parker, Gerard M. Salem
  • Publication number: 20180067163
    Abstract: An electronic device having a functional portion and a test portion. The test portion includes a boundary scan register formed by a plurality of test cells arranged in the body according to a register sequence, where first test cells are configured to form a serial-to-parallel converter and second test cells are configured to form a parallel-to-serial converter. The test cells are each coupled to a respective data access pin of the device and to a respective input/output point of the functional part and have a first test input and a test output. The boundary scan register defines two test half-paths formed, respectively, by the first test cells and by the second test cells. The first test cells are directly coupled according to a first sub-sequence, and the second test cells are directly coupled according to a second sub-sequence.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 8, 2018
    Inventor: Alberto Pagani
  • Publication number: 20180067164
    Abstract: A system includes a multiple input signature register (MISR) to receive outputs from M different scan chains in response to N test patterns applied to test an integrated circuit. The MISR provides N test signatures for the integrated circuit based on the outputs of the M different scan chains generated in response to each of the N test patterns. Each of the scan chains holds one or more test data bits that represent behavior of the integrated circuit in response to each of the N test patterns. A shift register is loaded from an interface and holds one of N comparison signatures that is used to validate a respective one of the N test signatures generated according to a given one of the N test patterns. A comparator compares each of the N test signatures with a respective one of the N comparison signatures to determine a failure condition based on the comparison.
    Type: Application
    Filed: December 30, 2016
    Publication date: March 8, 2018
    Inventors: NAMAN MAHESHWARI, WILSON PRADEEP, PRAKASH NARAYANAN
  • Publication number: 20180067165
    Abstract: An apparatus 2 for performing serial data communication with a target device 4, such as an integrated circuit, utilizes serial transfer circuitry 16 to perform a serial transfer of data to a communication register 26 in the target device 4 and serial retrieval circuitry 18 to retrieve an acknowledge signal 32 indicating whether or not the target device is ready to perform further processing following such a transfer. Delay control circuitry 20 serves to apply a predetermined delay period following the transfer of the serial data via the serial transfer circuitry before initiating the retrieval of the acknowledge signal. This predetermined delay period is controlled in dependence upon the ready status indicated by the acknowledge signals retrieved such that the proportion of acknowledge signals retrieved which indicate an unready status meets a predetermined condition, such as being less than a non-zero predetermined value.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 8, 2018
    Inventors: Russell John BUCKETT, Ian Craig MCFARLAND, Robert John WALKER
  • Publication number: 20180067166
    Abstract: One embodiment describes a switching device system, which includes a first single pole switching device that selectively connects and disconnects a first phase of electric power to a first winding of a three phase motor; a second single switching device that selectively connects and disconnects a second phase of electric power to a second winding of the three phase motor; in which the first and second single pole switching devices control temperature of the motor by, at a first time, connecting the first phase and the second phase electric power to the motor.
    Type: Application
    Filed: September 19, 2017
    Publication date: March 8, 2018
    Inventors: Christopher H. Bock, Christopher J. Wieloch, James J. Kinsella, Stefan T. Dziekonski
  • Publication number: 20180067167
    Abstract: A storage system includes a storage battery, a first deriver, a second deriver, and a corrector. The storage battery performs charging and discharging of electricity. The first deriver derives a first state of charge (SOC) based on a voltage of the storage battery when a current is not flowing to the storage battery. The second deriver derives a second SOC based on a battery capacity of the storage battery and an integrated value of a current flowing to the storage battery. The corrector corrects the battery capacity of the storage battery which is used by the second deriver based on a difference between the second SOC derived by the second deriver and the first SOC derived by the first deriver after the derivation of the second SOC. Furthermore, the corrector changes a correction quantity of the correction in accordance with a state of the storage battery.
    Type: Application
    Filed: February 19, 2015
    Publication date: March 8, 2018
    Applicant: Kabushiki Kaisha Toshiba
    Inventors: Makoto IDE, Mami MIZUTANI, Yukitaka MONDEN, Takenori KOBAYASHI, Tsutomu TANNO
  • Publication number: 20180067168
    Abstract: A secondary battery restoring method includes a first step of determining whether or not a value of an input-output characteristic of a secondary battery or a battery module is within a predetermined range of reference values, and a second step of adjusting the secondary battery or the battery module to a predetermined low SOC condition of from 0% to 20% SOC and thereafter leaving the secondary battery or the battery module to stand if, in the first step, the value of the input-output characteristic is determined to be outside the predetermined range of reference values.
    Type: Application
    Filed: September 5, 2017
    Publication date: March 8, 2018
    Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventor: Toshihiko MITSUHASHI
  • Publication number: 20180067169
    Abstract: A battery capacity measuring device that measures the battery capacity of a rechargeable battery includes an impedance measurement unit that measures the complex impedance of a rechargeable battery, which is a subject to measurement, based on application of measurement AC power, a parameter calculation unit that calculates a parameter that is a ratio of a difference between measured angular speeds of two complex impedances having different measured angular speeds in a diffusion region among a plurality of measured complex impedances to a difference between components of the two complex impedances, and a capacity calculation unit that calculates the capacity of the rechargeable battery based on information that is set in advance and indicates the relationship between the capacity of the rechargeable battery and the parameter and a parameter calculated by the parameter calculation unit.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 8, 2018
    Applicant: PRIMEARTH EV ENERGY CO., LTD.
    Inventors: Hiroki NISHI, Daisuke KOBA, Tetsuya OSAKA