Abstract: The present embodiments provide for compositions and methods that regulate microRNA-binding protein-mediated miRNA biogenesis; for example Lin28-mediated biogenesis of let-7; and in particular Lin28A-recruited 3? terminal uridylyl transferase (TUTase) uridylation of pre-let-7. A particular embodiment provide compositions and methods for screening for agents that inhibit TUTase-dependent Lin28A-mediated repression of let-7 miRNA.

Abstract: Antibodies, and antigen-binding fragments, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use, which are useful as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies.

Abstract: The present disclosure provides anti-CD73 binding molecules, e.g., antibodies and antigen binding fragments thereof. Also provided are pharmaceutical formulations comprising the disclosed compositions, and methods for the diagnosis and treatment of diseases associated with CD73-expression, e.g., cancer. Such diseases can be treated, e.g., by direct therapy with the anti-CD73 binding molecules disclosed herein (e.g., naked antibodies or antibody-drug conjugates that bind CD73), by adjuvant therapy with other antigen-binding anticancer agents such as immune checkpoint inhibitors (e.g., anti-CTLA-4 and anti-PD-1 monoclonal antibodies), and/or by combination therapies where the anti-CD73 molecules are administered before, after, or concurrently with chemotherapy.

Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising the antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the methods.

Abstract: The invention discloses methods for the generation of chimaeric human non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising the antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the methods.

Abstract: A process for the preparation of ethylene polymers comprising polymerizing ethylene, optionally with one or more ?-olefin comonomers, in the presence of: (i) a solid catalyst component comprising titanium, magnesium, halogen and optionally an internal electron-donor compound, (ii) an aluminum alkyl compound, and (iii) an antistatic compound selected among the hydroxyesters with at least two free hydroxyl groups, wherein the weight ratio of aluminum alkyl compound to solid catalyst component is higher than 0.80 and the weight ratio of antistatic compound to aluminum alkyl compound is higher than 0.10.

Abstract: A process for the preparation of ethylene ?-olefin copolymers by copolymerizing ethylene with ?-olefins in the presence of a catalyst formed by contacting a metallocene complex with a cocatalyst, wherein the metallocene complex is a metallocene complex according to formula I or a metallocene complex according to formula II, wherein M is chosen from the group of Ti, Zr and Hf; Q is halogen (F, Cl, Br, I) or an alkyl group comprising 1 to 20 carbon atoms; k is the number of Q groups, is an integer and equals the valence of M minus 2; and wherein R1, R2, R3 and R4 are identical or different and can be chosen from alkyl groups with 1-20 carbon atoms.

Abstract: Methods for producing catalyst systems with increased productivity are disclosed. The methods may comprise providing a catalyst composition comprising a solvent and a single-site catalyst component, heating an inert gas to a temperature in a range of from about 100° C. to about 150° C., and spray drying the catalyst composition in the presence of the inert gas to form a spray-dried catalyst system. Additionally, the methods may comprise providing a catalyst composition comprising a solvent, an activator, a filler material, a metallocene catalyst, and a Group 15-containing catalyst; heating an inert gas to a temperature in a range of from about 100° C. to about 150° C.; and spray drying the catalyst composition in the presence of the inert gas to form a spray-dried catalyst system.

Abstract: An isoprene polymerization catalyst composition includes: Component (a): a rare earth element compound having a rare earth element-oxygen bond or a rare earth element-sulfur bond; Component (b): an ionic compound; and Component (c): at least one compound selected from the group consisting of a compound of formula (X): YR1aR2bR3c and a compound having a repeating unit of formula (Y): (—Y(R1)O—) (where Y is a metal selected from groups 1, 2, 12 and 13 in a periodic table, R1 and R2 are C1-10 hydrocarbon groups or hydrogen atoms and R3is a C1-10 hydrocarbon group).

Abstract: The invention relates to methods for isolating and obtaining polychloroprene solids, wherein an aqueous polychloroprene dispersion is brought in contact with steam containing coagulant, whereby the polychloroprene solid coagulates.

Abstract: This invention relates to novel bridged a hafnium transition metal metallocene catalyst compounds having two indenyl ligands substituted at the 4 position, preferably 4 and 7 positions, with a C1 to C10 alkyl, where the 2 and 3 positions are hydrogen (assuming the bridge position is counted as the one position) and the bridging atom is carbon or silicon which is incorporated into a cyclic group comprising 3, 4, 5, or 6 silicon and/or carbon atoms that make up the cyclic ring.

Abstract: A temperature regulating article comprises a substrate and a polymeric phase change material bound to the substrate, wherein the polymeric phase change material is characterized by including a precisely branched polymer with substantially equally spaced repeating sidechains. In other embodiments the polymeric phase change material includes between 20 and 200 branches per 1000 carbon units, has a latent heat of at least 5 Joules per gram, and a transition temperature between 0° C. and 40° C.

Abstract: The present invention is directed to an acrylic copolymer composition prepared from a monomer composition. The monomer composition is essentially free of solvents having a boiling point less than 120° C. and essentially free of acid functional monomers. The monomer composition or acrylic copolymer composition comprises: (A) 30 to 70 percent by weight of a monomer having the structure (I): wherein (i) X is NR? or O, R? is hydrogen or is a linear or branched alkyl group having 1 to 18 carbon atoms, and R is a linear or branched alkyl group having 1 to 18 carbon atoms, or (ii) X is N or O and R is a linear or branched alkyl group bonded to X to form a 5- to 7-member ring; based on the total weight of monomers in the monomer composition; and (B) 30 to 70 percent by weight of at least one different ethylenically unsaturated monomer.

Abstract: Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.

Abstract: A method for a polymeric or nanocomposite material. The method includes assembling a multiphase hard-soft structure, where the structure includes a hard micro- or nano-phase, and a soft micro- or nano-phase that includes a polymeric scaffold. In the method, the polymeric scaffold includes dynamically interacting motifs and has a glass transition temperature (Tg) lower than the intended operating temperature of the material.

Abstract: The present invention relates to a method for producing polyisocyanates comprising iminooxadiazinedione groups, wherein at least one monomeric di- and/or tri-isocyanate is oligomerized in the presence of at least one catalyst and succinonitrile. The invention relates further to a reaction system for producing polyisocyanates comprising iminooxadiazinedione groups, and to the use of succinonitrile in the production of polyisocyanates comprising iminooxadiazinedione groups by catalyzed modification of monomeric di- and/or tri-isocyanates.

Abstract: Composition including at least one polymer containing silane groups and at least one zinc(II) complex compound of Znk(L)x(Y)2k-nx, where k is an integer from 1-10, x is 1, 2, 3, or 4, n corresponds to of ligand L, Y is ligand having ?1 charge, and L is ligand of where n is 1, 2, or 3, A is R4 or polyoxyalkylene group or group of polyoxyalkylated compound optionally having one or two terminal 1,3-ketoamide groups, R1 and R2 are hydrogen residue or monovalent saturated or unsaturated hydrocarbon group having 1-10 carbon atoms independently of each other or jointly bivalent alkylene group having 3-6 carbon atoms; R3 and R4 are hydrogen residue or monovalent saturated hydrocarbon group having 1-12 carbon atoms independently of each other, hydrocarbon group optionally contains one or more heteroatoms, or jointly bivalent alkylene group having 3-6 carbon atoms, which alkylene group optionally contains one or more heteroatoms.

Abstract: A composition capable of forming a heat-dissipation member having high thermal conductivity, and a heat-dissipation member. The composition for the heat-dissipation member of the present application contains a polymerizable liquid crystal compound having, at both terminals, a structure including an oxiranyl group or an oxetanyl group; a curing agent that cures the polymerizable liquid crystal compound; and an inorganic filler formed of nitride. A curing temperature of the composition for the heat-dissipation member is within or higher than the temperature range in which the polymerizable liquid crystal compound exhibits a liquid crystal phase, and within or lower than the temperature range in which the polymerizable liquid crystal compound exhibits an isotropic phase. The heat-dissipation member formed of such a composition can have excellent thermal conductivity owing to a synergistic effect between alignment of the liquid crystal compound and the inorganic filler formed of nitride.

Abstract: Methods and formulations for distortional thermosets are disclosed that display enhanced composite mechanical performances and robust sorption resistance. The composition includes an epoxy resin of formula (I): and a diamine curing agent. The resultant distortional thermoset compositions possess superior out-life requirements and advantageous reaction kinetics for preparing prepreg compositions and materials.

Abstract: Disclosed herein are methods of electrospinning poly(glycerol sebacate) (PGS) which allow stable PGS fibers and fibrous PGS constructs, scaffolds and grafts to be formed. In one example, a disclosed method includes generating PGS fibers by blending PGS prepolymer with a heat resistant synthetic carrier polymer, wherein the blend is electrospun into micro- or nano-fibers, and the PGS prepolymer is cross-linked into PGS with heat without using chemical cross-linkers. In another example, a disclosed method includes electrospinning a PGS and gelatin blend, wherein the PGS and gelatin composition are cross-linked by heat curing without using chemical cross-linkers. In another example, the method includes preparing an electrospinning precursor solution comprising blending PGS prepolymer with poly(lactic-co-glycolic acid) (PLGA) and a chemical cross-linker; electrospinning the prepared blend; and exposing the electrospun blend to an organic solvent to remove the PLGA.

Abstract: The present invention concerns a catalyst formulation comprising: (a) a Zn catalyst comprising a Zn compound having alcoholate ligand(s) derived from one or more polyols, and (b) a catalyst additive comprising a metal compound (i) having alcoholate ligand(s) derived from one or monohydric alcohol wherein the metal is selected from: (I) group 13 metals, preferably B, Al, Ga, and In, more preferably Al, (II) combinations of Al with group 14 metals or semi-metals, preferably a combination of Al and Si, and (III) combinations of at least two metals selected from (I) and (II). The present invention also relates to a process for polymerizing an epoxide monomer, preferably ethylene oxide, comprising carrying out the process in the presence of the catalyst formulation.

Abstract: The invention relates to a reactor in the form of a VK tube (VK: simplified continuous), for the polymerisation of polyamides, the reactor being subdivided into an upper and lower reactor region, which are controllable independently of each other. Likewise, the invention relates to a method for the production of polyamides in which such a reactor is used.

Abstract: A furan-based polyamide is prepared by the following steps: (1) preparing a furan-based oligomer of formula (1) H2N—R—(NH—CO—F—CO—NH—R)n—NH2 (1) where R is a hydrocarbon moiety and F is a furan (cyclo-C4H2O) moiety and n represents the average degree of oligomerization, and where n is within the range of 1 to 10 by reacting 2,5-furandicarboxylic acid or its derivative with a diamine at a temperature of at most 100° C.; (2) contacting the oligomer of step (1) with a bifunctional linker selected from an acid or a derivative thereof where the acid is furandicarboxylic acid or a non-aromatic dicarboxylic acid; provided that if the hydrocarbon moiety R is aromatic, then the bifunctional linker is an aromatic dicarboxylic acid or a derivative thereof, at a mole ratio of the oligomer to the difunctional linker within the range of 0.8 to 1.5 at polycondensation conditions, and (3) isolating the resulting polyamide.

Abstract: The present disclosure relates to a novel polyamide synthesized from biobased monomers. The novel polyamide comprises the repeating unit of formula I, described herein, in which R represents a covalent bond or a divalent hydrocarbon-based group chosen from saturated or unsaturated aliphatics, saturated or unsaturated cycloaliphatics, aromatics, arylaliphatics and alkylaromatics. The present disclosure also relates to a process for preparing the said polyamide, to its uses, and to articles and compositions comprising the said polyamide.

Abstract: The invention provides a non-particulate cross-linked poly-?-lysine polymer. The poly-?-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-?-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fiber. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilization of species, cell culturing and in chromatographic separation.

Abstract: Methods of forming a polyarylene sulfide and systems as may be utilized in carrying out the methods are described. Included in the formation method is a filtration process for treatment of a mixture, the mixture including a polyarylene sulfide, a salt byproduct of the polyarylene sulfide formation reaction, and a solvent. The filtration process includes maintaining the downstream side of the filter medium at an increased pressure. The downstream pressure can such that the boiling temperature of the mixture at the downstream pressure can be higher than the temperature at which the polyarylene sulfide is insoluble in the solvent.

Abstract: Novel polyfluoroalkylated alkenes and silicone compounds prepared therefrom are described.

Abstract: Predominately amino terminated phosphonamide oligomers and their use as flame retardant additives in polyamides and copolyamides without detracting from melt processability are described herein. Other important properties such as strength, modulus, dyeing and thermal stability are maintained.

Abstract: The present invention aims to provide an industrially advantageous method of producing a powdery pseudopolyrotaxane with a high inclusion ratio. The present invention relates to a method for producing a pseudopolyrotaxane, including: an inclusion step of mixing a polyethylene glycol and a cyclodextrin in an aqueous medium to form an aqueous dispersion of pseudopolyrotaxane that contains pseudopolyrotaxane particles in which the polyethylene glycol is included in the cavities of the cyclodextrin molecules in a skewered manner; and a drying step of drying the aqueous dispersion of pseudopolyrotaxane produced in the inclusion step to obtain the pseudopolyrotaxane. In the drying step, the aqueous dispersion of pseudopolyrotaxane is sprayed and dried in a heated gas-stream.

Abstract: A method for preparing a “preblend” of nano-structured carbon, such as nanotubes, fullerenes, or graphene, and a particulate solid, such as polymer beads, carbon black, graphitic particles or glassy carbon involving wet-mixing and followed by optional drying to remove the liquid medium. The preblend may be in the form of a core-shell powder material with the nano-structured carbon as the shell on the particulate solid core. The preblend may provide particularly improved dispersion of single-wall nanotubes in ethylene-?-olefin elastomer compositions, resulting in improved reinforcement from the nanotubes. The improved elastomer compositions may show simultaneous improvement in both modulus and in elongation at break. The elastomer compositions may be formed into useful rubber articles.

Abstract: The objective of the present invention is to provide a porous ultra-thin polymer film, and a method for producing said porous ultra-thin polymer film. The present invention provides a porous ultra-thin polymer film with a film thickness of 10 nm-1000 nm. In addition, the present invention provides a method for producing a porous ultra-thin polymer film, comprising the steps of: dissolving two types of mutually-immiscible polymers in a first solvent in an arbitrary proportion to obtain a solution; applying the solution onto a substrate and then removing the first solvent from the solution applied onto the substrate to obtain a phase-separated ultra-thin polymer film that has been phase-separated into a sea-island structure; and immersing the ultra-thin polymer film in a second solvent which is a good solvent for the polymer of the island parts but a poor solvent for a polymer other than the island parts to remove the island parts, thereby obtaining a porous ultra-thin polymer film.

Abstract: A film including a top ply, where at least the top ply contains 15 to 90 phr of at least one ethylene-based polymer having a Mooney viscosity (ML1+4, 121° C.) of 50 to 80 Mooney units and 10 to 85 phr of at least one polypropylene having an ISO 178 flexural modulus of greater than or equal to 400 MPa, and the film may be a single-ply or multi-ply film. In some aspects the ethylene-based polymer has a crystallinity of less than or equal to 30%. The top ply may further include at least one compatibilizer, which has, in some cases, a melt flow index MFI (230° C., 2.16 kg) of 0.1 to 4.0 g/10 min.

Abstract: A high gloss acrylonitrile butadiene styrene (ABS) sheet includes an ABS substrate, an intermediate film of poly(3,4-ethylenedioxythiophen)-polystyrene sulfonate formed on top of the ABS substrate, and a fluorinated resin film of poly(vinylidene fluoride-trifluoroethylene) formed on top of the intermediate film. A method of preparing the high gloss ABS sheet is also disclosed.

Abstract: The present invention relates to a wiper rubber (10) for a windshield wiper, comprising a wiper rubber substructure (1) with a wiper lip section (2) and a reinforcement section (4), the wiper rubber substructure (1) being uncoated and being formed from ethylene-propylene-diene rubber and/or ethylene-propylene rubber. In order to improve the wear resistance, wiping characteristics and wiping quality of the wiper rubber (10), the surface of the wiper rubber substructure (1) at least in a partial region (2c, 2c?) of the wiper lip section (2) has been treated with ultraviolet radiation. The present invention further relates to a process for producing a wiper rubber, to a correspondingly produced wiper rubber and to a windshield wiper equipped therewith.

Abstract: A method of enhancing hydrophilicity of a hydrophobic polymer material includes pre-treating the hydrophobic polymer material. The pre-treating includes treating the hydrophobic polymer material with a first atmospheric pressure plasma discharge in a first atmosphere including carbon dioxide to obtain a pre-treated polymer material. The method includes treating the pre-treated polymer material with a second atmospheric pressure plasma discharge in a second atmosphere in which an aerosol of an amine is introduced; the amine includes at least one hydrocarbon substituent. A substrate is provided that includes a hydrophobic polymer material having a modified interface. The modified interface includes amine functional groups grafted on the hydrophobic polymer material, the modified interface having a surface energy, which, measured after immersion in water at 20° C. for 3 days, differs from a surface energy of the hydrophobic polymer material by 20 mN/m or less.

Abstract: A process for producing expanded foam beads from pellets comprising at least one biodegradable polyester. The process comprises (i) producing a suspension comprising pellets in an aqueous suspension medium, (ii) impregnating the pellets present in the suspension from step (i) with at least one physical blowing agent by heating the pellet suspension to a depressurization temperature IMT, with stirring, to provide pellets laden with blowing agent in the suspension medium, and (iii) depressurizing the suspension obtained in step (ii) and cooling the depressurized suspension with a liquid aqueous coolant, in order to obtain the expanded foam beads. The blowing agent can be added in step I, or in step ii during the heating phase or following the heating phase. Following the heating phase, the suspension is maintained at a temperature in the range from IMT minus 5° C. to IMT plus 2° C. for 3 to 100 minutes, and the ratio of aqueous coolant to suspension medium is at least 0.3.

Abstract: A method for producing macro porous micro-clusters is proposed comprising at least the following individual steps in given order: a) synthesis of dispersed cross-linked polymeric latex primary particles starting from at least one monomer or oligomer using emulsion polymerization; b) swelling of the primary particles with a liquid comprising at least an additional charge of monomer and/or oligomer and a cross-linker, optionally further comprising functionalization agents; c) destabilization by increase of ionic strength (by adding a salt and/or acid and/or base) in a combination with application of shear, both being above the gel formation boundary of the phase diagram, until agglomerates composed of primary particles of the desired size are formed; d) polymerization of the agglomerates to form the macro porous micro-clusters. Furthermore the invention to relates to correspondingly produced micro-clusters and uses of such micro-clusters in particular for chromatographic purposes.

Abstract: The present invention relates to a method for preparing a polyolefin resin composition including the step of mixing a first resin chip including a first polyolefin resin and glass filaments and a second resin chip including a second polyolefin resin and an aerogel or glass bubbles, a polyolefin resin composition including a first resin chip including a first polyolefin resin and glass filaments and a second resin chip including a second polyolefin resin and an aerogel or glass bubbles, and a polyolefin resin molded article including an extrusion molded article of the polyolefin resin composition.

Abstract: A resin composition includes a cellulose ester resin having a weight average molecular weight of 10,000 to 75,000; sulfuric acid; and at least one metal element selected from the group consisting of Group 1 elements and Group 2 elements, wherein a ratio of the sum of the content [M1] of the Group 1 element and the content [M2] of the Group 2 element to the total amount of all the elements according to fluorescent X-ray spectroscopy is 0.052% by weight, and a molar ratio of the content [M1] of the Group 1 element, the content [M2] of the Group 2 element, and the content [S] of sulfur atoms (S) according to fluorescent X-ray spectroscopy satisfies a relationship of Expression 1: ([M1]/2)+[M2]?1.5×[S].

Abstract: A fully dense ceramic and/or other inorganic fiber containing elongated crystal grains in and around the fiber center and oriented along the fiber axis, with a smooth transition to more equiaxed grains towards the radial periphery of the fiber, and method for producing such.

Abstract: The present invention relates to the use of a fatty acid (meth)acrylic acid salt in a golf ball layer. The fatty acid (meth)acrylic acid salt may be added to one or more portions of a golf ball including a core, intermediate, or cover layer. For example, in one embodiment, the fatty acid (meth)acrylic acid salt may be blended with a polybutadiene rubber material. In another embodiment, the fatty acid (meth)acrylic acid salt of the present invention may be blended with an ionomer. In some embodiments, the fatty acid (meth)acrylic acid salt may be blended with a formulation including both a polybutadiene rubber component and an ionomer.

Abstract: A transparent composite material composition, comprises, based on a total amount of the transparent composite material: 90 to 99% by weight of a thermosetting urethane acrylate resin; and 1 to 10% by weight of an organic hydroperoxide initiator. Such a transparent composite material composition exhibits superior properties such as superior transparency, impact resistance, scratch resistance, and weather resistance while realizing weight reduction.

Abstract: A concept and synthesis technology for a composite nanoparticle material which can be used to develop nanocomposite films and suspension with 1) dynamic refractive index control across a wide temperature and wavelength of light, and specified refractive index range, or 2) magnetic susceptibility or electronic conductivity over a wide temperature, magnetic field and electric field range. Core-shell nanoparticles can be made from two or more materials whose temperature dependent, electric field dependent or magnetic field dependent properties compensate one another will dynamically maintain a targeted refractive index, electronic conductivity or magnetic susceptibility over a specified temperature, electric and/or magnetic field range. Mixtures of composite nanoparticles with complementary behavior can optionally be used to widen the operational range of the nanocomposite material further or dampen temperature dependency in a controlled manner, e.g.

Abstract: Polymeric compositions comprising as-received organic waste materials comprising an antioxidant component for enhanced thermal stability.

Abstract: The invention relates to vulcanizable rubber compositions comprising at least the following components: a) at least one functionalized polymer, b) at least one modified polybutadiene having a proportion of cis-1,4 units of >95% by weight and a proportion of 1,2-vinyl content of <1% by weight, the polybutadiene having been modified by means of sulphur chlorides after the polymerization, c) at least one silica, d) at least one further filler, e) at least one vulcanizing agent, f) at least one oil and g) optionally at least one further rubber additive.

Abstract: The invention relates to a heat-fusible weld seam for joining ground coating members, comprising a copolymer selected from the group of polymers containing acrylic acid, methacrylic acid or maleic anhydride, a polyethylene and a copolyamide.

Abstract: Thermoplastic polyolefins (TPOs) and/or thermoplastic vulcanizates (TPVs) are blended with low molecular weight propylene-dominated copolymers to provide polymeric compositions with an improved balance between processability and toughness. The compositions have improved processability by facilitating the ease with which a TPO or TPV, usually difficult to melt process, can be processed at high line speeds, which in turn improves the formation of the composition into articles.

Abstract: The present invention relates to advanced flame/fire retardant compositions for fabric, upholstery, carpet, barrier, automotive, building construction, communication, and consumer electronics applications. The flame retardant composition comprises: about 5-25 wt. % hydrogenated styrenic block copolymer, about 6-40 wt. % polyolefin, about 50-80 wt. % inorganic flame retardant, about 0-5 wt. % coating, about 0-5 wt. % functionalized styrenic block copolymer, about 0-7 wt. % agri-derived heat resistant liquid, about 0.05-1.0 wt. % antioxidant, and about 0-7 wt. % optional additives such as metal deactivator, colorant, filler, and/or lubricants, wherein said composition totals 100 wt. %. An article made from the flame retardant composition, such as film, fiber, cable, and wire insulation meets various European and U.S. standards. The flame retardant compositions possess a good balance of tensile strength, elongation, flame resistance, and processability that has previously been unobtainable.

Abstract: An additive composition that includes fluoropolymer, synergist, and fatty acid metal salt.

Abstract: A method of making a highly fluorinated polymers and resulting aqueous mixtures. The method comprising polymerizing one or more perfluorinated monomers in an aqueous emulsion polymerization in the presence of a polymerizable fluorinated emulsifier to form a perfluorinated polymer. The polymerizable fluorinated emulsifier has the formula X2C?CX(CF2)m(CH2)n[O—(CX2)p]q—[O—(CX2)r]s?[O—(CX2—CX2)]t—[(O)w—(CX2)u]v—[CH2]z—Y. The method also provides for isolating the highly fluorinated polymer and post-fluorinating the isolated highly fluorinated polymer.