Patents Issued in April 17, 2018
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Patent number: 9944550Abstract: There is provided a tempered glass plate, wherein a thickness of the tempered glass plate is less than or equal to 2.7 mm, wherein on a surface of the tempered glass plate, a plurality of stress marks are formed, wherein a distance between closest stress marks of the plurality of stress marks is less than or equal to 20 mm, wherein the surface of the tempered glass plate includes a first virtual circle that is formed by connecting points that are separated from a center of one of the plurality of stress marks by 2.5 mm, wherein the tempered glass plate includes a non elastic-wave region that is not affected by an elastic-wave generated during fracturing, and wherein, in the non elastic-wave region, an average number of cracks that exist in the first virtual circle is greater than or equal to 3.4.Type: GrantFiled: July 19, 2016Date of Patent: April 17, 2018Assignee: ASAHI GLASS COMPANY, LIMITEDInventors: Kazushige Yoda, Masao Fukami, Shinya Ohta, Yasumasa Kato, Shigeru Ezaki
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Patent number: 9944551Abstract: New glass compositions and applications thereof are disclosed. Embodiments of the present invention relate to glass compositions, to fiber glass strands, to chopped fiber glass strands, to nonwoven mats of glass fibers, and to other products and methods. A fiber glass strand comprises a plurality of glass fibers comprising the glass composition of the present invention.Type: GrantFiled: May 7, 2015Date of Patent: April 17, 2018Assignee: PPG Industries Ohio, Inc.Inventor: Hong Li
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Patent number: 9944552Abstract: Inorganic fibers having the composition: 10?Al2O3?50 mol %; 2?K2O?40 mol %; 30?SiO2?70 mol %; and in which SiO2+Al2O3+K2O>=80 mol % can be protected against surface crystallization of kalsilite by: including an amount of a nucleation promoting component effective to promote bulk crystallization in the glass; and/or providing on at least part of their surface, potassium scavenging materials.Type: GrantFiled: June 23, 2014Date of Patent: April 17, 2018Assignee: Morgan Advanced Materials plcInventors: Ronald Wainwright, Gary Jubb, Fontaine Fadiora
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Patent number: 9944553Abstract: The invention relates to a solar protection glazing comprising, on at least one of the faces of a glass substrate, a multi-layer stack comprising at least one layer absorbing solar radiation of at least 3 nm and dielectric coatings surrounding said solar radiation absorbing layer. According to the invention, the light reflection of the glass substrate coated with the multi-layer stack, measured on the substrate side, is at least 20% and is at least two times the light reflection of the glass substrate coated with the multi-layer stack measured on the stack side, and the reflection color on the substrate side has a colorimetric coordinate value a* of less than 2 and a colorimetric coordinate value b* of less than 5. The invention is particularly useful as an automobile glazing, in particular on the roof thereof, as a building glazing or as a household oven.Type: GrantFiled: June 27, 2014Date of Patent: April 17, 2018Assignee: AGC GLASS EUROPEInventors: Stijn Mahieu, Gaetan Di Stefano, Marc Hauptmann, Jacques Dumont
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Patent number: 9944554Abstract: Methods for chemically strengthening the edges of glass sheets are provided. Voids can be formed in a mother sheet. The edges of these voids may correspond to a portion of the new edges that would normally be created during separation and free shaping of the mother sheet. The mother sheet can then be immersed in a chemical strengthener. The edges of the voids can be chemically strengthened in addition to the front and back sides of the mother sheet. After thin film processing and separation, each of the resulting individual sheets has been chemically strengthened on both sides and on a portion of its edges.Type: GrantFiled: September 15, 2011Date of Patent: April 17, 2018Assignee: APPLE INC.Inventors: Seung Jae Hong, Casey J. Feinstein, Lili Huang, Sunggu Kang, Kuo-Hua Sung, John Z. Zhong
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Patent number: 9944555Abstract: A method for manufacturing a float glass includes a step of melting a glass raw material, a step of forming the glass melted in the melting step into a glass ribbon while floating the glass on a molten metal, and a step of annealing the glass ribbon. In the forming step, a gas or a liquid containing a molecule having a fluorine atom present therein is blown to the glass ribbon having a viscosity of from 1.0×104 to 2.5×1010 Pa·s.Type: GrantFiled: March 24, 2016Date of Patent: April 17, 2018Assignee: ASAHI GLASS COMPANY, LIMITEDInventors: Masanobu Shirai, Ryosuke Kato, Satoshi Miyasaka, Nobuaki Ikawa
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Patent number: 9944556Abstract: DTPA-coated synthetic calcined gypsum is provided with alpha-like properties and obtained by spray-coating the synthetic caclined gypsum with DTPA. Cementitious compositions comprising DTPA-coated synthetic calcined gypsum and low water demand are provided as well. Methods for controlling an open time of a cementitious slurry by increasing or decreasing the amount of DTPA-coated synthetic calcined gypsum in the slurry are provided as well.Type: GrantFiled: October 15, 2014Date of Patent: April 17, 2018Assignee: UNITED STATES GYPSUM COMPANYInventors: Dennis Mark Lettkeman, John Wesley Wilson, Mike L. Cloud, Brian K. Ball, Raymond A. Kaligian, Doug Blackburn
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Patent number: 9944557Abstract: The present disclosure relates to a bentonite modifier, comprising a water-soluble thiosulfate, a water-soluble alcohol compound, and a water-soluble amine compound, wherein the amounts of thiosulfate, the alcohol compound, and the amine compound are in the ratio of (0.3˜1):(0.3˜1):(0.3˜1). The present disclosure further relates to a bentonite-containing cement additive capable of resisting permeation and salt corrosion, comprising bentonite and said modifier, wherein the content of the bentonite modifier is 0.2˜5% of the bentonite by weight. Meanwhile, the present disclosure also provides use of the modified bentonite.Type: GrantFiled: November 21, 2013Date of Patent: April 17, 2018Inventor: Wuji Yin
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Patent number: 9944558Abstract: A wellbore cement composition includes substantially unhydrated cement powder and additive powder for cement. The additive powder is formulated from ingredients including a liquid additive for cement and solid carrier particles. The liquid additive is absorbed by the solid carrier particles. A wellbore cementing method includes using a dry cement composition, adding water to the dry cement composition, forming a cement slurry, placing the slurry in a wellbore, and setting the placed slurry. The dry cement composition contains substantially unhydrated cement powder and retarder powder for cement. The retarder powder contains a retarder absorbed by solid carrier particles.Type: GrantFiled: March 21, 2016Date of Patent: April 17, 2018Assignee: BAKER HUGHES, A GE COMPANY, LLCInventors: Mark A. Vorderbruggen, Guido G. Narvaez, Diana Cardona, Dong Shen
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Patent number: 9944559Abstract: A new water-based inorganic binder composition includes inorganic binder, cellulose ether and microcrystalline cellulose. A new additive for water-based inorganic binder compositions includes cellulose ether and microcrystalline cellulose. A method for improving the properties of water-based inorganic binder compositions includes blending a combination of cellulose ether and microcrystalline cellulose in the water-based binder composition.Type: GrantFiled: June 23, 2011Date of Patent: April 17, 2018Assignee: Dow Global Technologies LLCInventors: Sonja Scharlemann, Joerg Neubauer, Matthias Knarr
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Patent number: 9944560Abstract: A density controlled cold fusion concrete cementitious spray applied fireproofing material including a mixture of water, one or more of silicon dioxide, expanded glass, vermiculite, bottom ash, perlite, expanded shale, expanded polystyrene, and sulfonated formaldehyde, or other lightweight aggregates of various diameter sizes ranging from about 0.025 mm to about 12.5 mm in diameter; anhydrous or hydrous sodium or potassium metasilicate; waste from steel production consisting of Granulated Ground Blast Furnace Slag (GGBFS); high calcium or low calcium waste from coal combustion (fly ash or bottom ash); sodium tetraborate, sodium citrate dihydrate, citric acid, or boric acid; and an alkali-resistant micro-fiber.Type: GrantFiled: June 6, 2017Date of Patent: April 17, 2018Assignee: Geopolymer Solutions LLCInventor: Rodney Zubrod
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Patent number: 9944561Abstract: A dielectric material includes a composite sintered body in which conductive particles are dispersed in an insulating material, in which a dielectric constant at a frequency of 40 Hz is 10 or higher, and a difference between a maximum dielectric loss value and a minimum dielectric loss value at a frequency of 1 MHz in a surface of the composite sintered body is 0.002 or less.Type: GrantFiled: March 9, 2015Date of Patent: April 17, 2018Assignee: SUMITOMO OSAKA CEMENT CO., LTD.Inventors: Masayuki Ishizuka, Hiroaki Nagatomo
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Patent number: 9944562Abstract: Ceramic granules having high reflectivity and a preparation method for the same comprise sand core particulates and at least one coating thereon, wherein said sand core particulates contain calcined tobelite that is obtained by calcining the tobelite ore at 700-1200° C.; and said sand core particulates are coated with an inorganic coating, and then calcined at 800-1200° C. to obtain ceramic granules. Said ceramic granules have a particle size of 0.1-3.5 mm, and have a solar reflectivity SR of not lower than 80% and a staining index DL* of lower than 6%. Said ceramic granules produce a solar reflectivity of not lower than 70% when being applied to the asphalt roll/sheet and a solar reflectivity of not lower than 72% when being applied to the polyurethane foam sheet.Type: GrantFiled: February 1, 2016Date of Patent: April 17, 2018Assignee: Shijiazhuang Nikka Mintech Co., Ltd.Inventors: Zhijie Li, Hongwei Lu
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Patent number: 9944563Abstract: A ceramic component is generally provided that includes a silicon-based layer comprising a silicon-containing material (e.g., a silicon metal and/or a silicide) and about 0.001% to about 85% of an In-containing compound. For example, the silicon-based layer can be a bond coating directly on the surface of the substrate. Alternatively or additionally, the silicon-based layer can be an outer layer defining a surface of the substrate, with an environmental barrier coating on the surface of the substrate. Gas turbine engines are also generally provided that include such a ceramic component.Type: GrantFiled: September 16, 2016Date of Patent: April 17, 2018Assignee: General Electric CompanyInventors: Glen Harold Kirby, Julin Wan
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Patent number: 9944564Abstract: A method of fabricating a ceramic article includes providing a porous body that includes a plurality of fiber bundles that has an intra-bundle porosity and an inter-bundle porosity, infiltrating the intra-bundle porosity and the inter-bundle porosity with a mixture of particles in a liquid carrier, the particles having an average size selected with respect to at least the intra-bundle porosity, removing the liquid carrier from the porous body to deposit the particles in the intra-bundle porosity and in the inter-bundle porosity, infiltrating a preceramic polymer into a remaining intra-bundle porosity and a remaining inter-bundle porosity, and thermally converting the preceramic polymer to a ceramic material.Type: GrantFiled: October 21, 2014Date of Patent: April 17, 2018Assignee: United Technologies CorporationInventors: Shahram Amini, Xia Tang, Wayde R. Schmidt, Tania Bhatia Kashyap
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Patent number: 9944565Abstract: After a wet blasting treatment for jetting a slurry, which contains spherical alumina as abrasive grains in a liquid, to the surface of a ceramic substrate 10 of aluminum nitride sintered body so that the ceramic substrate 10 has a residual stress of not higher than ?50 MPa and so that the surface of the ceramic substrate 10 to be bonded to the metal plate 14 has an arithmetic average roughness Ra of 0.15 to 0.30 ?m, a ten-point average roughness Rz of 0.7 to 1.1 ?m and a maximum height Ry of 0.9 to 1.Type: GrantFiled: November 20, 2012Date of Patent: April 17, 2018Assignees: DOWA METALTECH CO., LTD., TOKUYAMA CORPORATIONInventors: Hideyo Osanai, Yukihiro Kitamura, Hiroto Aoki, Yukihiro Kanechika, Ken Sugawara, Yasuko Takeda
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Patent number: 9944566Abstract: The present invention relates to a process for the manufacture of a grout for concrete comprising a stage of mixing a hydraulic binder and water, characterized in that the process comprises a stage of deep freezing the water in the solid form.Type: GrantFiled: April 8, 2015Date of Patent: April 17, 2018Assignee: SOLETANCHE FREYSSINETInventors: Alain Chaniat, Didier Jean Botti, Riad Sarraf, Christian Honnorat
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Patent number: 9944567Abstract: A method of inhibiting an irregular aggregation of a nanosized powder includes (A) providing a nanosized ceramic powder to perform thereon a thermal analysis and thereby attain an endothermic peak temperature; (B) performing an impurity-removal heat treatment on the nanosized ceramic powder at a temperature higher than the endothermic peak temperature; (C) switching the nanosized ceramic powder from a temperature environment of the impurity-removal heat treatment to an environment of a temperature higher than a phase change temperature of the nanosized ceramic powder, followed by performing a calcination heat treatment on the nanosized ceramic powder in the environment of the temperature higher than the phase change temperature of the nanosized ceramic powder, wherein the nanosized ceramic powder skips the temperature environment between impurity-removal heat treatment and calcination heat treatment to shun generating a vermicular structure, avoid crystalline irregularity and abnormal growth, reduce particleType: GrantFiled: May 10, 2016Date of Patent: April 17, 2018Assignee: NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Li-Jiuan Chen, Yen-Chung Chen, Hong-Fang Huang, Yu-Chun Wu
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Patent number: 9944568Abstract: An encapsulated particle comprises a core particle, a transferrable-pesticide disposed about the core particle, and a polyurethane layer disposed about the transferrable-pesticide. The core particle comprises a fertilizer, such as urea. The transferrable-pesticide can comprise a dinitroaniline, such as pendimethalin. The polyurethane layer is generally formed from a reaction mixture having a maximum temperature of no greater than about 30° C. The polyurethane layer inhibits the transferrable-pesticide from transferring to a surface different from the core particle when the encapsulated particle physically contacts the surface. A method of forming the encapsulated particle comprises the steps of encapsulating the core particle with the transferrable-pesticide to form an intermediate-particle, combining an isocyanate and a polyol to form the reaction mixture, and encapsulating the intermediate-particle with the reaction mixture to form the polyurethane layer of the encapsulated particle.Type: GrantFiled: November 15, 2013Date of Patent: April 17, 2018Assignee: BASF SEInventors: Raymond A. Neff, Alexander Gershanovich, Johanne Wilson
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Patent number: 9944569Abstract: A granularized sulfonated humate powder material is provided that includes a sulfonated cationic humate composed of at least one of humic acid, fulvic acid, or a combination thereof in the form of granules of from 0.1 to 6 millimeters in size. The humate powder material is water soluble with limited dusting and the ability to form a concentrated solution for application. A process of formulating the sulfonated potassium humate powder in granular form includes a lignin or lignosulfonate being metered into a powder of sulfonated potassium humate to allow for granulation without a solubilizing the powder by matching a lignin particle size to a particle sizing of said powder. The lignin or lignosulfonate and the powder are mixed into the granular form with a granule size of 0.1 to 6 millimeters.Type: GrantFiled: September 1, 2017Date of Patent: April 17, 2018Assignee: THE ANDERSONS INC.Inventors: John Uliveto, Chris Taylor, Eric Dearth
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Patent number: 9944570Abstract: A desensitizing agent and method which desensitizes triacetone triperoxide (TATP). The agent includes a common polymer dissolved in a volatile solvent, which allows for direct, rapid application on-site, providing for safer movement and transport of the explosive. Drop heights in impact test results of treated TATP were twice that of neat TATP or TATP treated with conventional agents. The agent is composed of non-toxic, inexpensive components with the polymer delivered in a solvent vehicle, which quickly volatilizes after application and exhibits compatibility with TATP and conventional explosives.Type: GrantFiled: February 20, 2014Date of Patent: April 17, 2018Assignee: The United States of America as Represented by the Secretary of the NavyInventors: Kenneth Basom, Bryan Milani
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Patent number: 9944571Abstract: The present invention relates to a process for the one-pot hydrogenation and dehydration or isomerization of an organic compound, and to a catalyst composition for this process comprising transition metal particles having particle size below 50 nm supported on a material comprising at least one fluorinated polymer (P), wherein polymer (P) bears —SO2X functional groups, X being selected from X? and OM, X? being selected from the groups consisting of F, Cl, Br and I; and M being selected from the group consisting of H, and alkaline metal and NH4.Type: GrantFiled: November 16, 2015Date of Patent: April 17, 2018Assignee: SOLVAY SPECIALTY POLYMERS ITALY S.P.A.Inventors: Claudio Oldani, Luca Merlo, Pierluigi Barbaro, Carmen Moreno-Marrodan, Francesca Liguori
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Patent number: 9944572Abstract: A method for coupling an alkane with an alkene using a hydrogen transfer catalyst and an alkene dimerization catalyst to form one or more higher molecular weight hydrocarbons.Type: GrantFiled: May 16, 2017Date of Patent: April 17, 2018Assignee: California Institute of TechnologyInventors: David Leitch, Jay A. Labinger, John E. Bercaw, Yan Choi Lam
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Patent number: 9944573Abstract: The present disclosure provides natural gas and petrochemical processing systems, including oxidative coupling of methane reactor systems that may integrate process inputs and outputs to cooperatively utilize different inputs and outputs in the production of higher hydrocarbons from natural gas and other hydrocarbon feedstocks. The present disclosure also provides apparatuses and methods for heat exchange, such as an apparatus that can perform boiling and steam super-heating in separate chambers in order to reach a target outlet temperature that is relatively constant as the apparatus becomes fouled. A system of the present disclosure may include an oxidative coupling of methane (OCM) subsystem that generates a product stream comprising compounds with two or more carbon atoms, and a dual compartment heat exchanger downstream of, and fluidically coupled to, the OCM subsystem.Type: GrantFiled: April 13, 2017Date of Patent: April 17, 2018Assignee: SILURIA TECHNOLOGIES, INC.Inventors: Guido Radaelli, Suchia Duggal, Joel Cizeron, Wayne Schammel, Franciscus J. A. Martens
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Patent number: 9944574Abstract: The invention discloses a continuous process for producing high-pure quadricyclane, in which “a reaction-rectification integral process” or “a reaction followed by rectification process” may be employed. The two processes both use a novel composite catalyst which is obtained by loading an organic photo-sensitizer on a solid photocatalyst, and the composite catalyst has a high activity and a good stability. In the reaction-rectification integral process, the composite catalyst is used by being blended with rectification fillers or covering the rectification fillers, so as to achieve the integration of the reaction and the rectification. In the reaction followed by rectification process, the composite catalyst and the rectification fillers are placed separately from each other. The two processes achieve a relatively short residence time of reactants, produce highly-pure quadricyclane, and reduce the formation of cokes.Type: GrantFiled: May 23, 2014Date of Patent: April 17, 2018Assignee: TIANJIN UNIVERSITYInventors: Jijun Zou, Xiangwen Zhang, Li Wang, Qingfa Wang
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Patent number: 9944575Abstract: Adsorption towers are filled with adsorbents that adsorb methane gas in coal mine gas and perform a PSA cycle. For each of adsorption towers, a plurality of different pressure states of the internal pressure of the adsorption tower are set as an intermediate pressure state. As a pressure equalization step, an initial pressure equalization step of transferring the gas in one of the adsorption towers that is in a high pressure state to another one of the adsorption towers that is in an intermediate pressure state, and a final pressure equalization step of transferring the gas in one of the adsorption towers that is in the high pressure-side intermediate pressure state to another one of the adsorption towers that is in the low pressure state are performed.Type: GrantFiled: February 27, 2014Date of Patent: April 17, 2018Assignee: Osaka Gas Co., Ltd.Inventors: Shota Kawashima, Takahisa Utaki
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Patent number: 9944576Abstract: The present invention provides a method for selectively separating a straight-chain conjugated diene with high purity from a mixture containing the straight-chain conjugated diene and at least one type of straight-chain olefin. The method involves separating the straight-chain conjugated diene from the mixture containing the straight-chain conjugated diene and the straight-chain olefin using a zeolite membrane composite. The composite contains a porous support and a zeolite layer formed on the surface and in the fine pores of the support, and the zeolite contains an alkali metal cation.Type: GrantFiled: September 30, 2015Date of Patent: April 17, 2018Assignees: WASEDA UNIVERSITY, JXTG Nippon Oil & Energy CorporationInventors: Masahiko Matsukata, Motomu Sakai, Yasuhito Sasaki, Tatsuo Hamamatsu, Nobuhiro Kimura
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Patent number: 9944577Abstract: The polymerization of monomers may be at least partially reduced or inhibited by introducing an effective amount of an additive. The additive may be or include at least one hydroquinone, such as but not limited to, 2,6-di-tert-butyl hydroquinone, 2,5 di-tert-butyl hydroquinone, 3,5 di-tert-butyl hydroquinone, 3,5 di-methyl hydroquinone, 3,6 di-tert-butyl hydroquinone, and combinations thereof. The polymerizable monomers may be or include, but are not limited to styrene, butadiene, isoprene, acrylic acid, acrylonitrile, vinyl acetate, and combinations thereof.Type: GrantFiled: July 22, 2014Date of Patent: April 17, 2018Assignee: Baker Hughes, a GE company, LLCInventors: Hua Mo, Roger D. Metzler
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Patent number: 9944578Abstract: The present invention provides a process for the preparation of a (hydro)(chloro)fluoroalkene by contacting a reagent stream comprising a hydrochlorofluoroalkane with a catalyst in a reactor to dehydrochlorinate at least a portion of the hydrochlorofluoroalkane to produce a product stream comprising the (hydro)(chloro)fluoroalkene and hydrogen chloride (NCI), wherein the catalyst is selected from the group consisting of metal oxide catalysts, metal halide catalysts, zero-valent metal catalysts, carbon-based catalysts and mixtures thereof, and wherein (i) the catalyst is chlorinated prior to contacting it with the reagent stream comprising the hydrochlorofluoroalkane; and/or (ii) the contacting step is carried out in the presence of a HCI co-feed.Type: GrantFiled: July 27, 2015Date of Patent: April 17, 2018Assignee: MEXICHEM AMANCO HOLDING S.A. DE C.V.Inventors: Andrew Paul Sharratt, Claire Nicola Rees, Maxine Doran
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Patent number: 9944579Abstract: A phosphorus ligand-free, mild, efficient and complete catalytic hydrogenation process is for the sustainable production of terminal diols from renewable terminal dialkyl esters with improved yield. Soluble, phosphorus ligand free Ru (II)-pincer type complexes can be used as catalysts in the hydrogenation process.Type: GrantFiled: January 15, 2016Date of Patent: April 17, 2018Assignee: Council of Scientific & Industrial ResearchInventors: Ekambaram Balaraman, Manoj Kumar Sahoo
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Patent number: 9944580Abstract: A solubilizer is used to stabilize crude polyol produced from biomass.Type: GrantFiled: December 6, 2012Date of Patent: April 17, 2018Assignee: SIKA TECHNOLOGY AGInventors: Dieter Honert, Hans Knauber, Thomas Müller
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Patent number: 9944581Abstract: The present invention provides processes, methods, and systems for converting biomass-derived feedstocks to liquid fuels and chemicals. The method generally includes the reaction of a hydrolysate from a biomass deconstruction process with hydrogen and a catalyst to produce a reaction product comprising one of more oxygenated compounds. The process also includes reacting the reaction product with a condensation catalyst to produce C4+ compounds useful as fuels and chemicals.Type: GrantFiled: April 18, 2017Date of Patent: April 17, 2018Assignee: Virent, Inc.Inventors: Andrew Held, Elizabeth Woods, Randy Cortright, Matthew Gray
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Patent number: 9944582Abstract: The present disclosure relates to a method for purifying an acid, wherein the method comprises: a) producing a crude product mixture by a partial oxidation reaction, wherein the crude product mixture comprises acrylic acid and acetic acid; b) purifying the crude product mixture by distillation using a high-boiling solvent to purify the acrylic acid; and c) purifying the crude product mixture by distillation using a low-boiling solvent to purify the acetic acid.Type: GrantFiled: May 19, 2014Date of Patent: April 17, 2018Assignee: SAUDI BASIC INDUSTRIES CORPORATIONInventors: Mustapha N. Karime, Faisal Baksh, Mubarik Bashir, Zeeshan Nawaz
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Patent number: 9944583Abstract: The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system (CNS), or the brain, caused or mediated by NFkB, IL-6, IL-6-R, NADPH oxidase (Nox), and/or superoxide and/or hydrogen peroxide production by a NADPH oxidase, including for example ameliorating, treating, reversing or preventing schizophrenia, psychosis, delirium, e.g., post-operative delirium, drug-induced psychosis, psychotic features associated with frailty syndrome (FS), aging, depression, dementias; traumatic war neurosis, post traumatic stress disorder (PTSD) or post-traumatic stress syndrome (PTSS), Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's Disease), and/or Multiple Sclerosis (MS). The invention also provides methods for purifying a C60 fullerene, C3 (tris malonic acid C60) or malonic acid derivatives.Type: GrantFiled: April 22, 2016Date of Patent: April 17, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Laura L. Dugan, Marie Margarita Behrens, Sameh Ali
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Patent number: 9944584Abstract: The invention describes processes to selectively remove or reduce the mineral acid content substantially from compositions comprising a solvent and levulinic acid, wherein the levulinic acid was derived from the reaction between various biomass materials and a mineral acid or an organic acid catalyst.Type: GrantFiled: March 2, 2015Date of Patent: April 17, 2018Assignee: GFBIOCHEMICALS LIMITEDInventors: Brian D. Mullen, Vivek Badarinarayana
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Patent number: 9944585Abstract: The present invention relates to the use of a specific organic compound as flavor and fragrance material. Furthermore the invention relates to flavor and fragrance formulations comprising such a specific organic compound.Type: GrantFiled: October 7, 2013Date of Patent: April 17, 2018Assignee: DSM IP ASSETS B.V.Inventors: Raphael Beumer, Johannes Tschumi, Michael Gressly
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Patent number: 9944586Abstract: Methods and systems for producing alkyl hydroxyalkanoate from hydroxy carboxylic acid recovery bottoms. The methods generally comprise the steps of obtaining a hydroxy carboxylic acid recovery bottom, adding a mono-alcohol to the hydroxy carboxylic acid recovery bottom to obtain a first mixture, heating the first mixture in the presence of a catalyst to form a reaction product, distilling the reaction product, and recovering an alkyl hydroxyalkanoate fraction.Type: GrantFiled: October 17, 2014Date of Patent: April 17, 2018Assignee: CARGILL, INCORPORATEDInventors: Timothy Walter Abraham, Anthony Louis Duran, Stephen C. Edgar, Ravi R. Gokarn
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Patent number: 9944587Abstract: A process for vapor-phase carbonylation of methanol to methyl formate, whereby a feed gas containing methanol, carbon monoxide, hydrogen and oxygen is passed through a reactor loaded with a supported nano-scaled platinum group metal heterogeneous catalyst to produce methyl formate by a vapor-phase carbonylation reaction, under reaction conditions with a space velocity of 500-5000 h?1, a temperature of 50-150° C. and a pressure of 0.01-2 MPa. Supported nano-scaled platinum group metal heterogeneous catalysts are prepared via ultrasonic dispersion and calcination. Methyl formate is produced and isolated under relatively mild conditions.Type: GrantFiled: June 12, 2014Date of Patent: April 17, 2018Assignee: FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCESInventors: Zhongning Xu, Guocong Guo, Siyan Peng, Zhiqiao Wang, Qingsong Chen, Mingsheng Wang, Yuangen Yao
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Patent number: 9944588Abstract: A method for preparing methyl formate in which a raw material containing formaldehyde, methanol and/or dimethyl ether is introduced into a first reaction zone to come into contact with a catalyst A, and a component I is obtained by separation, the component I is introduced into a second reaction zone to come into contact with a catalyst B so as to obtain, by separation, methyl formate as a product, dimethyl ether that is returned to the first reaction zone and a component II that is returned to the second reaction zone, the catalysts have a long service life, the reaction conditions are mild, and the utilization rate of the raw material is high, thus enabling a continuous production for large-scale industrial application.Type: GrantFiled: November 17, 2014Date of Patent: April 17, 2018Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Youming Ni, Wenliang Zhu, Yong Liu, Hongchao Liu, Zhongmin Liu, Lina Li, Shiping Liu, Hui Zhou
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Patent number: 9944589Abstract: The present invention relates to cyclopropyl derivatives of general formula (I), wherein A, R1, and R2 are as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.Type: GrantFiled: December 3, 2013Date of Patent: April 17, 2018Assignee: Istituto Europeo di Oncologia S.r.l.Inventors: Mario Varasi, Paola Vianello, Florian Thaler, Paolo Trifiro′, Ciro Mercurio, Giuseppe Meroni
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Patent number: 9944590Abstract: The present invention is generally directed to novel crystalline forms of the acetate salt of (1S,3S,4R)-4-((3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol and processes for their preparation.Type: GrantFiled: June 23, 2016Date of Patent: April 17, 2018Assignee: Aquinox Pharmaceuticals (Canada) Inc.Inventors: Lloyd F. Mackenzie, Jeffery R. Raymond, Curtis Harwig, Ana Fernandez Casares
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Patent number: 9944591Abstract: The invention relates to the 4-((2E,4E,6E)-octa-2,6,4-trienamid)butanoic acid; its use in the therapeutic and cosmetic field for topical application to the skin to achieve a combined antioxidant activity against ROS together with an anti-inflammatory effect and an effect of promoting the production of hyaluronic acid, so as to oppose at the same time the oxidizing action of free radicals and inflammatory effects, in order to preserve the physiological conditions of human epidermis and skin homeostasis and prevent skin aging (anti-aging); the compositions for therapeutic and cosmetic use which comprise 4-((2E,4E,6E)-octa-2,6,4-trienamid)butanoic acid as active ingredient, formulated with excipients for topical use suitable for local administration on the skin.Type: GrantFiled: August 4, 2015Date of Patent: April 17, 2018Assignee: Giuliani S.p.A.Inventors: Giammaria Giuliani, Anna Benedusi, Barbara Marzani, Sergio Baroni, Elena Pini
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Patent number: 9944592Abstract: The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, methods of using prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing common diseases and/or disorders such as spasticity and/or acid reflux disease. The disclosures herein also relate to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof which are suitable for oral administration and to sustained release oral dosage forms thereof.Type: GrantFiled: December 22, 2016Date of Patent: April 17, 2018Assignee: XENOPORT, INC.Inventors: Mark A. Gallop, Fenmei Yao, Maria J. Ludwikow, Thu Phan, Ge Peng
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Patent number: 9944593Abstract: A process for the preparation of the fluoroalkyl sulfonate salt of a nitrogen-based organic base said process comprising the step of reacting a fluoroalkyl sulfonyl halide with an organic base selected from the group consisting of tertiary amines, pyridines, amidines and guanidines.Type: GrantFiled: September 30, 2014Date of Patent: April 17, 2018Assignee: SOLVAY SPECIALTY POLYMERS ITALY S.P.A.Inventors: Cristiano Monzani, Vito Tortelli
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Patent number: 9944594Abstract: The invention relates to a catalyst comprising an active component based on molybdenum and on potassium and a support based on hydroxyapatite, and also to a process for preparing said catalyst and a process for producing methyl mercaptan in a catalytic process by reaction of carbon monoxide, sulphur and/or hydrogen sulphide and hydrogen, comprising the use of said catalyst.Type: GrantFiled: March 28, 2014Date of Patent: April 17, 2018Assignee: ARKEMA FRANCEInventors: Georges Fremy, Patrice Barre, Karine Sanchou, Alexia Cordova, Carole Lamonier, Pascal Blanchard
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Patent number: 9944595Abstract: The present invention provides a process for producing a perfluoropolyoxyalkylene peroxide compound comprising a step of reacting a perfluoroalkene with oxygen, wherein the reaction of the perfluoroalkene with oxygen is performed under ultraviolet irradiation and in the presence of a fluorine source.Type: GrantFiled: December 8, 2016Date of Patent: April 17, 2018Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Keiichirou Watanabe, Hideki Nakaya, Motohisa Shino, Tatsuya Takakuwa, Kazunori Morimoto
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Patent number: 9944596Abstract: Provided is a heterocyclic compound having a superior RBP4-lowering action and useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4. A compound represented by the formula (I): wherein each symbol is as defined in the Description, or a salt thereof has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.Type: GrantFiled: October 22, 2015Date of Patent: April 17, 2018Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Yoshihiro Banno, Masahiro Kamaura, Takahiko Taniguchi, Kazuaki Takami, Koichiro Fukuda, Shigekazu Sasaki
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Patent number: 9944597Abstract: The present invention provides polysubstituted pyrrole compounds, pharmaceutically effective salts, prodrugs, solvates and hydrates thereof, having antimitotic, antiproliferative and cytotoxic activity, activity against cells expressing the drug efflux protein, P-glycoprotein, or cells expressing the ?-III isotype of tubulin and antitumor activity. Also provided are methods of utilizing these compounds for inhibiting the proliferation of cancer cells as well as their medical use, in particular for treating cancer, including drug resistant cancer.Type: GrantFiled: September 16, 2014Date of Patent: April 17, 2018Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, VIRGINIA COMMONWEALTH UNIVERSITY, UNIVERSITY OF RICHMONDInventors: Glen E. Kellogg, Chenxiao Da, Ashutosh Tripathi, John T. Gupton, Nakul Telang, James A. Sikorski, Susan L. Mooberry, Cristina Rohena
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Patent number: 9944598Abstract: The present invention concerns mono- or di-substituted indole derivatives (I) which are useful to prevent or treat dengue viral infections and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.Type: GrantFiled: September 30, 2015Date of Patent: April 17, 2018Assignees: Janssen Pharmaceuticals, Inc., Katholieke Universiteit LeuvenInventors: Bart Rudolf Romanie Kesteleyn, Jean-François Bonfanti, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Dorothée Alice Marie-Eve Bardiot, Arnaud Didier M Marchand
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Patent number: 9944599Abstract: The present invention relates to processes for preparing ?-aminosulfone compounds. The provided compounds are useful intermediates in the preparation of sulfone group containing isoindoline-based compounds, in particular apremilast.Type: GrantFiled: May 27, 2015Date of Patent: April 17, 2018Inventors: Gaj Stavber, Jerome Cluzeau