Abstract: A velocity vector calculating unit 40 obtains velocity vectors at various coordinates in a blood flow, on the basis of signals obtained by transmitting and receiving ultrasonic waves, thereby generating a plurality of vector frames, each formed from velocity vectors at a plurality of coordinates. An interpolation processing unit 50 generates interpolated frames by employing an interpolation process between two adjacent vector frames, and adds one or a plurality of such interpolated frames between said vector frames. The interpolation processing unit 50 generates each interpolated frame, formed from interpolated vectors at a plurality of coordinates, by means of an interpolation process based on velocity vectors between the two adjacent vector frames.

Abstract: A blood pressure detection method is used for the sphygmomanometer including an envelope, an air pressure control mechanism, an ultrasonic wave transmission mechanism and an ultrasonic wave reception mechanism. The blood pressure detection method includes: applying a control signal to the air pressure control mechanism and the ultrasonic wave transmission mechanism, to inflate and deflate the envelope, and enable the ultrasonic wave transmission mechanism to transmit an ultrasonic detection signal toward the to-be-detected body part at a predetermined interval; monitoring an ultrasonic reflection signal received by the ultrasonic wave reception mechanism; determining a detection time point for the blood pressure detection in accordance with a frequency of the ultrasonic reflection signal during the deflation of the envelope; and determining a blood pressure value for the blood pressure detection in accordance with a pressure value of air within the envelope at the detection time point.

Abstract: A blood pressure measurement apparatus, a portable pressure measurement apparatus, and a calibration method for the blood pressure measurement apparatus are provided. The blood pressure measurement apparatus includes a pulse wave measurer configured to measure pulse wave data of a subject while a user pressurizes and depressurizes the blood pressure measurement apparatus, using a portable pressure measurement apparatus, and a communicator configured to receive pressure data that is applied to the blood pressure measurement apparatus during the pressurizing and the depressurizing of the blood pressure measurement apparatus, from the portable pressure measurement apparatus, the pressure data being measured by the portable pressure measurement apparatus. The blood pressure measurement apparatus further includes a processor configured to update a blood pressure estimation formula, based on the received pressure data and the measured pulse wave data.

Abstract: A pulse wave measuring apparatus includes a visible light receiver having a first surface and a pulse wave calculator. When a vehicle with the visible light receiver is viewed from a side, the first surface is in a first region between a first optical path of first reflection light and a second optical path of second reflection light, first light comes from an eye of a user on a seat of the vehicle, second light comes from a cheek of the user, an upper end of a rearview mirror of the vehicle reflects the first light to produce the first reflection light and reflects the second light to produce the second reflection light, and the pulse wave calculator calculates a pulse wave of the user on the basis of a waveform of visible light received by the visible light receiver via the first surface and outputs the calculated pulse wave.

Abstract: A method and monitor for monitoring vital signs. In one embodiment, the vital signs monitor includes a housing sized and shaped for fitting adjacent the ear of a wearer and an electronic module for measuring vital signs. The electronic module for measuring vital signs is located within the housing and includes a plurality of vital signs sensing modules in communication with a processor. The plurality of sensing modules includes at least two of the modules selected from the group of a ballistocardiographic (BCG) module, a photoplethysmographic (PPG) module, an accelerometer module, a temperature measurement module, and an electrocardiographic (ECG) module. In one embodiment, the processor calculates additional vital signs in response to signals from the plurality of vital signs sensing modules.

Abstract: A brain-computer interface is disclosed. The brain-computer interface includes a spatially-adjustable animalia-engaging portion connected to a computing resource interface portion. The computing resource interface portion includes an actuator that is connected to at least one spatial-adjuster-component of the spatially-adjustable animalia-engaging portion. The actuator is configured to rotate the at least one spatial-adjuster-component for extending a distal portion of a length of a micro-electrode of at least one subassembly of the spatially-adjustable animalia-engaging portion beyond a distal end of a micro-electrode guide portion of the spatially-adjustable animalia-engaging portion.

Abstract: An optical electrode having a plurality of electrodes, including a recording electrode having a roughened surface and an optical light source configured to emit light, wherein at least a portion of the light impinges on the recording electrode. Also disclosed are methods of producing an optical electrode and an opto-electronic neural interface system.

Abstract: A method for automatic detection of CHF and AF with 12-bit RR interval time series using an electrocardiogram by using normalized RMSSD, sample entropy, and Shannon entropy, includes: (a) testing the electrocardiogram according to time from a subject; (b) calculating normalized RMSSD of data obtained at step (a); (c) calculating sample entropy value of the data obtained at step (a); (d) calculating Shannon entropy value for each of sections divided at step (a); and (e) comparing the normalized RMSSD, the sample entropy, and the Shannon entropy values calculated at steps (a),(b), and (c), and detecting CHF and AF.

Abstract: Method and software are provided to format a probability index that reflects where an electroencephalogram (EEG) pattern lies within the spectrum of wakefulness to deep sleep, which employs a computer/microprocessor that performs frequency domain analysis of one or more discrete sections (Bins) of the EEG to determine the EEG power at specified frequencies, optionally calculates the total power over specified frequency ranges, assigns a rank to the power at each frequency, or frequency range, assigns a code to the Bin that reflects the ranking of the different frequencies or frequency ranges, and determines an index that reflects where said EEG pattern within said Bin(s) lies within the spectrum of wakefulness to deep sleep by use of a reference source, such as a look-up table or other suitable decoding instrument.

Abstract: A system for the assessment and monitoring of the fetal electrocardiogram (ECG) and heart rate in a pregnant mother comprises wearable mechanical-electronic sensors, e.g., embedded in a wrist or arm band, which can measure the mechanical pulse signals from the mother, and an abdomen patch which can measure the combined ECG signals of the fetus and mother. The wrist or arm unit and the abdominal patch unit communicate wirelessly. By signal processing and gating out the maternal ECG signals as correlated with the mechanical maternal pulse signals, the fetal ECG and heart rate can be measured and monitored. These measurements may be displayed on the wrist or arm band device, or wirelessly through a remote device, mobile phone or computer. Electronic-mechanical sensors can also be embedded in the abdominal patch to measure uterine electromyogram (EMG), uterine contractions and fetal movements, to be correlated with the fetal ECG.

Abstract: This document discusses, among other things, systems and methods to map an electrical waveform to a user-perceivable input. Some system examples include at least one electrode configured to sense neural activity in a patient, a mapping controller configured to receive an electrical waveform from the at least one electrode and map the sensed neural activity to a user-perceivable output based on the sensed neural activity, and a user interface operably connected to the mapping controller and configured to provide the user-perceivable output to a user.

Abstract: A patch including a fiducial layer, an adhesive, and a sensor layer. The fiducial layer having a surface adapted to secure to a portion of skin on a patient, wherein the fiducial layer further includes a plurality of fiducial markers having at least one of acoustic properties, material density, and proton content different from those of human tissue. The adhesive being disposed along the surface of the fiducial layer. The sensor layer removably secured to a side of the fiducial layer and positionable distal the skin of the patient. The sensor layer including a plurality of sensors evenly spaced from one another, adapted to be in electrical communication with the skin of the patient, and each adapted to measure at least electric field or impedance.

Abstract: The present invention refers to the field of ophthalmology, and in particular to that of devices and methods for supporting the diagnosis of important eye pathologies such as Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), anomalies and dysfunctions of the retina and of sight in general such as degeneration of the retinal structure of the optical nerve and of the visual cortex. More specifically, the invention concerns a new device and method for recording the electroretinogram (so-called ERG) of an eye, i.e. the bioelectric response of the retina induced by a light stimulus, through the eyelid.

Abstract: A method of identifying brain structures is disclosed. The method comprises imaging the cortex of the brain via inversion recovery magnetic resonance imaging, such that at least two areas are zeroed in terms of their longitudinal relaxation times, and associating the two areas with different brain structures, thereby identifying brain structures.

Abstract: A new apparatus, algorithm, and method are introduced herein to support navigation and placement of an intravascular catheter using the electrical conduction system of the heart (ECSH) and control electrodes placed on the patient's skin.

Abstract: Embodiments of the present disclosure include a medical device, comprising an elongate shaft extending along a shaft longitudinal axis and comprising a shaft proximal portion and a shaft distal portion. A navigational assembly is connected to the shaft distal portion and extends along the shaft longitudinal axis. The navigational assembly includes a navigational electrode positioning feature and a magnetic position sensor positioning feature.

Abstract: Various methods and apparatuses are presented for an ingestible capsule that includes a digital, ingestible sensor component—or ingestible sensor—embedded into the capsule. The ingestible sensor component may be configured to activate upon coming into contact with conductive fluid, such as a body's stomach fluid. Once activated, the ingestible sensor component may be configured to perform various tasks, such as transmitting one or more signals and obtaining biometric data about the body that ingested the capsule.

Abstract: A system and method are presented for use in monitoring one or more conditions of a subject's body. The system includes a control unit which includes an input port for receiving image data, a memory utility, and a processor utility. The image data is indicative of data measured by a pixel detector array and is in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern. The memory utility stores one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body. The processor utility is configured and operable for processing the image data to determine one or more corresponding body conditions; and generating output data indicative of the corresponding body conditions.

Abstract: A stabiliser for an organic polymer comprising a) poly (dicyclopentadiene-co-p-cresol) (Formula 1); b) a sterically hindered phenol of Formula II; and c) an alkyl thio methyl phenol of Formula III; and d) and optionally a phosphate antioxidant.

Abstract: The technology disclosed herein relates to, in part, a gas sampling device. According to some aspects, the gas sampling device has a housing defining an airflow aperture, a gas testing chamber and an airflow pathway extending from the airflow aperture to the gas testing chamber. The housing also defines a sensor receptacle configured to removably hold a disposable sensor test strip within the gas testing chamber and a docking structure configured to be received by a docking station.

Abstract: Patient support apparatuses include a frame, support surface, and a controller. The controller provides notification to a user of a service event relating to the patient support apparatus. The controller limits functionality of a component of the patient support apparatus based upon a severity of the service event. The controller may also, or alternatively, detect when a control is activated by a user and, in response to such activation, determine whether the patient support apparatus has been marked for use or marked for servicing. If marked for use, the controller responds in a first manner, and if marked for service, the controller responds in a different manner. In other embodiments, a method is provided for determining an order in which multiple patient support apparatuses should be service. In still other embodiments, the patient support apparatus automatically changes to an unusable configuration when in need of high priority service.

Abstract: The invention discloses apparatus, and the method of using it, comprising one, or more, electronic sensors attached to a part(s) of a human or animal's body. The patient then performs an activity, or has an activity performed on them, and the results of the measured parameters are recorded by the sensor and processed, or downloaded and processed. The sensor may include a range of instrumentation, e.g. accelerometers, magnetometers, gyroscopes, force sensors, etc. to record positions (in the X, Y and Z planes), movements, angular movements, forces, stresses in bones/joints, etc. The use of the apparatus and method are appropriate to medical treatments, and perfecting sporting or dancing techniques and the results are processed to give the clinician or coach appropriate information to improve the problem being addressed. Methods for measuring lateral angular movement of hinged joints and spinal extension are taught.

Abstract: A method including obtaining a first electrocardiography [“ECG”] reading from a test subject when the test subject is believed to not suffer from blood volume loss and obtaining a second ECG reading from the test subject when the test subject is in an unknown condition regarding blood volume loss. The first ECG reading and the second ECG reading are obtained using the same electrode positions on the test subject and include sets of ECG signals which, based on experimental data, respond to small decrease in blood volume by a statistically significant strength decrease. If the second ECG reading exhibits a statistically significant strength decrease compared with the first ECG reading, an alert condition is raised, which indicates potential small decrease in blood volume. The method can be embodied as a stand-alone ECG apparatus or as an add-on unit to an ECG apparatus.

Abstract: The present invention relates to a point-of-care (POC) diagnostic device adaptable to environmental changes and a control method thereof. The POC diagnostic device includes a measurement unit configured to perform a POC diagnosis, an information acquisition unit configured to acquire environmental information of the POC diagnostic device, and a control unit configured to predict a temperature of the measurement unit on the basis of the environmental information acquired by means of the information acquisition unit and correct a measurement value of the measurement unit or control the POC diagnostic device on the basis of the predicted temperature of the measurement unit.

Abstract: An oxygen saturation measuring sensor is capable of increasing reliability of information of parts having different depth and includes a pad attachable to a human body; plural light sources arranged on the pad to be adjacent in a separate state, and irradiate near-infrared light; plural light receiving elements arranged on the pad to be adjacent in a separate state and correspond one to one to the plural light sources with reference to a common center with an innermost side of the plural light sources, and that receive transmitted light from the corresponding plural light sources; and a ROM unit that stores a reference value through measuring transmitted light using a phantom in advance and stores a light receiving amount of the transmitted light received by the plural light receiving elements.

Abstract: Apparatus and methods provide wireless, disposable, continuous pulse oximeter sensor technology, useful and beneficial for a number of applications including relatively extended periods of data collection, and/or packaged in compact and easy-to-use assemblies. Economic fabrication and use provides flexible methodologies that can reduce the overall costs of monitoring and collecting patient's physiological data, and provide relatively greater ease and comfort to the patient. A disposable wireless continuous pulse oximeter sensor has a reduced emitter-detector separation, a low-power frontend, and a low-cost processor that sends waveforms to a host device so that the host can calculate and display the parameters of interest. Complications created by the reduced distance between emitter and detector are minimized by using an emitter-detector assembly with an optically dark background, and a bandage for improved optical compliance.

Abstract: Apparatus configured to detect congenital heart disease (CHD) in newborns may comprise a body with a cavity configured to receive a hand or foot of a newborn. Sensor pairs of the apparatus may be configured scan such that the best signals can be selected, which can accommodate for movements of the newborn and/or facilitate impartialness as to which body part is inserted in the apparatus. Positions of the sensor pairs may be adjusted to ensure contact with the newborn's skin. A disposable cover may protect the newborn's skin from contacting the apparatus. The apparatus may include a pressure device so that CHD threshold values can be adjusted for different altitudes. The apparatus may integrate with electronic medical record (EMR) systems.

Abstract: A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer.

Abstract: A safety connector has a needle, and includes a tubular protective sleeve with a distal section, having a movable wall portion arranged in the peripheral wall thereof. The movable wall portion is selectively movable between a retracted position and a protection position. In the retracted position, the movable wall portion is aligned with the peripheral wall of the proximal section of the tubular protective sleeve. In the protection position, the movable wall portion projects into the inner space of the tubular protective sleeve.

Abstract: The system comprises a measurement system which measures an index of non-conscious adjustments achieved by a human user, as a composite index of user-specific physiological data and user-specific behavioural data, a calculation system calculating a pattern index representative of the location of the user inside a mental suffering grid comprising patterns of mental suffering from a predictive model, and pre-established structured experimental data descriptive of relationships between values of index of non-conscious adjustments achieved by experimental human users and said experimental human user's mental suffering historical data.

Abstract: A system and urine sensing devices for and method of monitoring kidney function is disclosed, wherein acute kidney injury (AKI). Namely, a kidney function monitoring system provides a portable urine monitor system that can provide real-time and continuous feedback about urine output and/or level of at least one urinary component (e.g., sodium). The kidney function monitoring system further comprises at least one urine sensing device, wherein the urine sensing device comprises a digital weight scale, a stand onto which a urine collection vessel can be positioned, and an interface between the digital weight scale and the stand that transfers the force of the stand and contents of the urine collection vessel to the digital weight scale. Further, the portable monitoring device comprises an adaptive and modular self-learning algorithm for the real-time assessment of AKI risk.

Abstract: The various embodiments disclosed here relate to systems, methods, and devices for monitoring bladder health. Certain implementations are directed to patients who require daily catheterization. The various embodiments have at least one tube coupled to a catheter, a pressure sensor, a pump, and a processor. Certain embodiments include a digital device with a software application capable of displaying the monitored readings.

Abstract: An apparatus, module, methods and systems for automated, standardized assessment and analysis of a human olfactory system's odor detection ability as an indicator or predictor of cognitive impairment or change in cognitive health, and other health conditions such as diabetes. Notably, the present invention is operable for use across all age groups of humans and provides quantitative detection and analysis of a human olfactory system's detection ability compared to a relevant demographic population.

Abstract: A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb?oxyHb).

Abstract: A method for early detection of bone deficiency in a patient, comprising: collecting NMR signals of a bone marrow volume in a bone of the patient having normal bone density levels which are not indicative of bone deficiency as indicated by X-ray; and analyzing said collected NMR signals to detect at least a presence or absence of a preclinical stage of bone deficiency in said bone.

Abstract: Devices, systems, and methods to receive and analyze biometric measurements from a customer service agent are provided. The analysis of the biometric measurements may be used to identify correlations between the biometric measurements, agent health, and agent performance. These correlations may then be used to route communications to the agent and/or modify the performance and/or increase the heath of the agent. The biometric measurements may also be correlated to an empathy level of the agent.

Abstract: An audio signal processing device (20) includes: an acquirer (210) configured to acquire biological information of a human subject; a processor (240) configured to identify at least one of a breathing cycle and a heartbeat cycle of the human subject, based on the biological information; and an effect imparter (250) configured to impart to an audio signal (SD) a frequency characteristic that changes at a cycle set in accordance with either the breathing cycle or the heartbeat cycle.

Abstract: The present invention relates to a device, system and method for detecting illness- and/or therapy-related fatigue of a person in an easy and reliable way. For this purpose the device comprises an input unit (20) for obtaining white blood cell count data related to the person's white blood cell count, hemoglobin level data related to the person's hemoglobin level and cortisol level data related to the person's cortisol level, and an analyzer (21) for detecting illness- and/or therapy-related fatigue of the person based on the obtained white blood cell count data, hemoglobin level data and cortisol level data.

Abstract: A signal acquisition device (100) of sleep breathing state based on bio-impedance and a monitoring system are provided. The signal acquisition device (100) includes a signal acquisition unit (101), a processing control unit (102), a data storage unit (103) and a wireless communication unit (104). The signal acquisition unit (101) includes electrodes (1011, 1012), a chest impedance acquisition module (1013) connected with the electrodes (1011, 1012), a heart rate acquisition module (1014) connected with the electrodes, and a snore acquisition module (1015). The signal acquisition unit (101) can collect signal data through three channels synchronously, chest impedances and heart rate signals are acquired by using bio-impedance technology, and snore audio signals are combined to monitor sleep breathing state. Furthermore, wireless signal transmission is used to prevent directly connecting with the patient via wires, the device is simple and cheap, convenient to wear, and applicable to domestic utilization.

Abstract: An example of a system for providing a patient with pain management includes a pain monitoring circuit. The pain monitoring circuit may include parameter analyzer circuitry and pain score generator circuitry. The parameter analyzer circuitry may be configured to receive and analyze one or more timing parameters and one or more baroreflex parameters allowing for determination of baroreflex sensitivity (BRS) of the patient. The one or more timing parameters are indicative of time intervals during which values of the one or more baroreflex parameters are used to determine the BRS. The pain score generator circuitry may be configured to compute a pain score using an outcome of the analysis. The pain score is a function of the BRS during the time intervals and indicative of a degree of pain of the patient.

Abstract: Devices and methods including wearable monitoring devices for a user's wrist that may be configured to intelligently and automatically decide when to monitor a user without requiring direct user input.

Abstract: An apparatus has a housing adapted for mechanical coupling with a skull of a human. A first sensor is positioned in the housing to collect linear motion signals. A second sensor is positioned in the housing to collect rotational motion signals. A processor is positioned in the housing connected to the first sensor and the second sensor. The processor is configured to process the linear motion signals and the rotational motion signals to derive a cumulative impact power measure of repetitive sub-concussive head impacts. The cumulative impact power measure is compared to a threshold indicative of the onset of neural tissue deformations corresponding to physiological changes from repetitive sub-concussive head impacts. An alert is supplied when the cumulative impact power measure is proximate the threshold.

Abstract: A method of monitoring a health status of a patient using a monitoring system comprising a pair of finger ring electrocardiogram (ECG) monitors. The monitoring system also includes at least one electronic component comprising a system on a chip (SoC) that features a data store and a processor. Biopotential signals from the left-hand finger of the patient (a first reading) and biopotential signals from the right-hand finger of the patient (a second reading) are received by the conductors of the respective ECG monitors, and correlated by detecting and removing signal latency between the first reading and the second reading. Analysis instructions executed by at least one of the respective processors of the ECG monitors identify a physiological condition of the patient from the correlated reading.

Abstract: Implant (e.g., sensory implant) positionable within subject's left heart atrium, for facilitating functional activity thereof, such as sensing or/and measuring physiological conditions or/and parameters. Implant includes: implant body housing physiological parameter sensing or/and measuring means; coupling means for coupling with an implant deployment device; and septum gripper having a flexible gripping sleeve fixedly connected to implant body wall, and selectively shapeable to pass through organ wall septum opening, and for gripping onto organ wall, such that implant body is fixatable or/and stabilizable across organ wall and through septum opening, to facilitate sensing or/and measuring in subject's body organ.

Abstract: A device for determining a heart rate of a user has a PPG sensor and an accelerometer to compensate for acceleration artifacts within the PPG signal. The device transforms time domain PPG and accelerometer signals into the frequency domain using a Fourier transformation and utilizes the Fourier coefficient magnitudes as indicative of the probability of candidate heart rate values. Candidate heart rate values are determined at sampling times over a time interval and a most probable heart rate path during the time interval is determined using a reward/penalty algorithm.

Abstract: A bio-signal quality assessment apparatus, a bio-signal quality assessment method, a bio-signal measurement parameter optimization apparatus, and bio-signal measurement parameter optimization apparatus method are provided. The bio-signal quality assessment apparatus includes a processor configured to determine a moving average of a bio-signal, and assess a quality of the bio-signal, based on a comparison between the determined moving average and the bio-signal.

Abstract: Accurate detection of anomaly in sensor signals is critical and can have an immense impact in the health care domain. Accordingly, identifying outliers or anomalies with reduced error and reduced resource usage is a challenge addressed by the present disclosure. Self-learning of normal signature of an input sensor signal is used to derive primary features based on valley and peak points of the sensor signals. A pattern is recognized by using discrete nature and strictly rising and falling edges of the input sensor signal. One or more defining features are identified from the derived features based on statistical properties and time and frequency domain properties of the input sensor signal. Based on the values of the defining features, clusters of varying density are identified for the input sensor signal and based on the density of the clusters, anomalous and non-anomalous portions of the input sensor signals are classified.

Abstract: A system determines onset of a prediabetic state and associated risk of type 2 diabetes without evidential symptoms. In an implementation, a computer implemented method for monitoring an onset and progress of prediabetes in an individual includes periodically capturing an insulin level of an individual and a blood glucose level of the individual over a predetermined time interval for a predefined period, deriving an insulin production trend or a relative insulin resistivity trend over the predefined period, wherein the relative insulin resistivity is a ratio of an insulin level and a blood glucose level, wherein the trends are indicative of trend categories comprising an increasing trend, a steady trend and a decreasing trend, and determining a status of prediabetes in the individual based on at least one of the insulin production trend, relative insulin resistivity trend, and personal data of the individual.

Abstract: The present invention relates to a device and a method for detecting a feature of an arterial blood pressure (ABP) waveform. The feature detecting method of an ABP waveform according to an exemplary embodiment of the present invention includes: searching a peak and a trough; detecting a systolic peak based on a time interval between a peak and a neighboring peak and an average pressure value; detecting a pulse onset with respect to a trough directly before the systolic peak; extracting a candidate of a dicrotic notch based on a magnitude of the systolic peak and a measurement time; detecting a point having a lowest pressure value among candidates of the dicrotic notch as a dicrotic notch and detecting a dicrotic peak based on the dicrotic notch; and classifying the detected dicrotic notches into a normal notch and a transient notch.

Abstract: A measurement device includes: a calculation unit that calculates a blood flow index regarding a waveform of a blood flow signal indicating a temporal change in a blood flow rate of a subject; and a determination unit that determines whether there is stenosis or atresia of a blood vessel of the subject according to the blood flow index.