Patents Issued in June 21, 2018
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Publication number: 20180169291Abstract: Disclosed are a medical fiberous structure and a method for preparing the same, wherein the medical fiberous structure comprises calcium carboxymethyl cellulose and a chitosan compound, at least one of the calcium carboxymethyl cellulose and the chitosan compound having a fibrous shape.Type: ApplicationFiled: June 24, 2016Publication date: June 21, 2018Applicant: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGYInventors: Jung Nam IM, Song Jun DOH, Tae Hee KIM, Yoonjin KIM, Chaehwa KIM, Gyu Dong LEE, Gahee KIM
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Publication number: 20180169292Abstract: Provided are a silicone wound dressing, a method of manufacturing thereof and a method of using thereof. The silicone wound dressing has a silicone dressing base material and an amorphous carbon coating formed on the silicone dressing base material. The amorphous carbon coating is formed by subjecting the silicone dressing base material to a plasma polymerization in a plasma device under an atmosphere of a mixed gas comprising a hydrocarbon gas and an oxygen-containing gas. The silicone wound dressing has excellent oxygen permeability and is less likely to adhere to the wound. The speedy recovery of the wound is promoted by covering the wound with the silicone wound dressing.Type: ApplicationFiled: December 16, 2016Publication date: June 21, 2018Inventors: Hirotsugu Yasuda, Werner Akira Yasuda
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Publication number: 20180169293Abstract: A hydrolyzed collagen dough produced from bovine collagen and methods for producing the collagen dough from bovine hides is provided. The collagen dough comprises water, bovine collagen, sodium benzoate and hydrochloric acid. To produce the collagen dough, the corium layer is separated from bovine hides and treated. The collagen dough may be used, for example, in biomedical applications, such as cell technology/tissue engineering, suture materials, or film and sponges for skin grafting. The collagen dough may further comprise chitosan.Type: ApplicationFiled: December 15, 2017Publication date: June 21, 2018Inventors: Eugene Goldfarb, Masayuki Mimasu, Rod Moore, Richard E. Battersby
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Publication number: 20180169294Abstract: The present invention relates to new compositions for sclerotherapy. In particular, the invention relates to the use of light activated biocompatible glues and catheter for the application of said glue. The catheter of the present invention comprises a light source for the glue activation.Type: ApplicationFiled: March 27, 2015Publication date: June 21, 2018Applicant: Swiss VX Venentherapie und Forschung GmbHInventor: Johann Christof RAGG
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Publication number: 20180169295Abstract: The present disclosure provides a film composed of a polymer mixture, wherein the polymer mixture includes: a hydrophobic composition including polycaprolactone (PCL); and at least one hydrophilic polymer selected from a group consisting of: alginate, gelatin, chitosan, hyaluronic acid, collagen, demineralized bone matrix (DSM), carboxymethyl cellulose (CMC), fibrin, polyoxyethylene, polyethylene glycol (PEG) and polyvinylpyrrolidone, wherein the weight ratio of the hydrophobic composition to the at least one hydrophilic polymer is about 1:0.01-100, and wherein the film has the effect of preventing leakage from a surgical wound or a diffuse wound.Type: ApplicationFiled: December 22, 2016Publication date: June 21, 2018Applicant: Industrial Technology Research InstituteInventors: Ming-Chia YANG, Wei-Hong CHANG, Yun-Han LIN, Kun-Mao KUO, Li-Jie LIN, Tai-Horng YOUNG
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Publication number: 20180169296Abstract: A hydrophilic intraocular lens (IOL) with high refractive index comprising at least one copolymer comprising: ((a) a first monomeric subunit comprising (i) a polymerized (meth)acrylate group and an aliphatic carbon moiety comprising at least two hydroxyl substituents or (ii) a polymerized (meth)acrylamide group, (b) a second monomeric subunit different from the first monomeric subunit comprising a polymerized (meth)acrylate group, at least one side group comprising (i) an aryloxy moiety comprising at least one halogen, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized (meth)acrylate group, wherein the aliphatic carbon moiety comprises optionally at least one hydroxyl substituent, (c) a third monomeric subunit different from the first and second monomeric subunits comprising a polymerized (meth)acrylate group and at least one alkoxyalkoxyalkyl side group.Type: ApplicationFiled: May 4, 2017Publication date: June 21, 2018Applicant: Benz Research and Development Corp.Inventors: Patrick H. Benz, Adam Reboul
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Publication number: 20180169297Abstract: The present invention concerns an injectable composition comprising FVII and a filler, and its use for preventing or treating body and skin defects, especially folds, wrinkles, skin depressions and scars, while diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation.Type: ApplicationFiled: June 10, 2016Publication date: June 21, 2018Applicant: Laboratoire Français du Fractionnement et des BiotechnologiesInventors: Abdessatar Chtourou, Jean-Luc Plantier, Philippe Mondon
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Publication number: 20180169298Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.Type: ApplicationFiled: February 13, 2018Publication date: June 21, 2018Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
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Publication number: 20180169299Abstract: The invention relates to a method for coating an implant (1), in particular a prosthesis, by applying charged particles (T) by means of iontophoresis to at least one section (10, 20; 110, 120) of the implant surface (3, 13). In the method, charged particles are accelerated in an electromagnetic field (E) and hit the surface (3, 13) of the implant in order to form a coating on the implant at least in some sections. The charged particles have at least one active ingredient.Type: ApplicationFiled: March 25, 2015Publication date: June 21, 2018Inventor: Helmut D. LINK
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Publication number: 20180169300Abstract: Techniques for modifying the surface of implantable devices, such as bioprosthetic valves, to improve the biocompatibility of the implantable devices are provided. In particular, a customizable, non-fouling surface coating may be formed on the surface of implantable devices that improves the biocompatibility of the implantable devices and has the potential to further reduce the occurrence of complications for patients of all ages. Additionally, various molecules of interest to specifically promote endothelialization of the implantable device may be added to the surface coating, which may facilitate the formation of an endothelial layer on the surface of the implantable device that would naturally maintain a non-thrombogenic, non-immunogenic environment in the long-term.Type: ApplicationFiled: June 1, 2016Publication date: June 21, 2018Inventors: Monica Fahrenholtz, Kathryn Jane Grande-Allen
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Publication number: 20180169301Abstract: A viable disc regenerative composition has a micronized material of nucleus pulposus and a biological composition made from a mixture of mechanically selected allogeneic biologic material derived from bone marrow having non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components; and wherein the mixture is compatible with biologic function and further includes non-expanded whole cells. The biological composition is predisposed to demonstrate or support elaboration of active volume or spatial geometry consistent in morphology with that of disc tissue. The viable disc regenerative composition extends regenerative resonance that compliments or mimics disc tissue complexity.Type: ApplicationFiled: January 6, 2017Publication date: June 21, 2018Applicant: Vivex Biomedical, Inc.Inventors: Harry Thomas Temple, Timothy Ganey, Stephanie Gonzalez, Tracy Scott Anderson, Shabnam Namin
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Publication number: 20180169302Abstract: Devices and methods for the treatment of open and closed wound spinal cord injuries are disclosed. For example, described herein are devices and methods for mitigating secondary injury to, and promoting recovery of, spinal cord primary injuries. More particularly, certain embodiments of the present invention are directed to polymeric mini-tubes that may be used for the treatment of spinal cord injuries. In addition, other embodiments are directed to polymeric “fill-in” bandages that may be used for the treatment of spinal cord injuries. For example, an erodible, or biodegradable, form of biocompatible polymer of the present invention is fabricated for surgical implantation into the site of the spinal cord injury.Type: ApplicationFiled: February 14, 2018Publication date: June 21, 2018Inventors: Robert S. Langer, Rajiv Saigal, Yang Teng
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Publication number: 20180169303Abstract: The present invention discloses a low viscosity composition comprising enamel matrix derivative (EMD) proteins in a suitable pharmaceutical carrier, said composition having a pH between pH 3.8-4.2, and a viscosity of less than 50 mPa s at 22° C., which, when applied to a porous bone graft material, improves and/or enhances bioactivity and osteoconduction of said bone graft material. The present invention consequently discloses a bone graft material which has been bioactivated using a low viscosity composition comprising enamel matrix derivative (EMD) proteins and which displays enhanced biocompatibility and improved bone regeneration after implantation.Type: ApplicationFiled: July 9, 2015Publication date: June 21, 2018Applicant: STRAUMANN HOLDING AGInventors: Alessandra Apicella, Peggy Heunemann
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Publication number: 20180169304Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.Type: ApplicationFiled: February 13, 2018Publication date: June 21, 2018Inventors: FRANCOIS BOURDON, Stephane Meunier
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Publication number: 20180169305Abstract: Drug delivery coatings and devices including the same are described herein. The drug delivery coating has a first coated layer with non-ionic polymer and photogroups, a second coated layer with acid polymer in contact and hydrogen bonded with the first layer, particles with hydrophobic therapeutic agent, and cationic agent. The coating can be provided on a balloon catheter, and the particles and cationic agent can be transferred to tissue during a medical procedure, such as an angioplasty procedure, for a therapeutic effect.Type: ApplicationFiled: December 14, 2017Publication date: June 21, 2018Inventors: Joram Slager, Rick Murphy
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Publication number: 20180169306Abstract: An implantable medical electrical lead is connectable to an electrical header of an implantable pulse generator. The lead includes a lead body, at least one electrode, a lead terminal, and a lead boot. The lead body extends from a proximal end to a distal end. The at least one electrode is disposed at the distal end of the lead body. The lead terminal is disposed at the proximal end of the lead body and configured to connect the lead to the electrical header. The lead boot is formed of an elastic polymer infused with at least one antibiotic drug. A portion of the lead boot is configured to be disposed within the electrical header when the lead is connected to the electrical header.Type: ApplicationFiled: December 13, 2017Publication date: June 21, 2018Inventors: Angelo Fruci, Arthur J. Foster, Joseph T. Delaney, JR., Danielle Frankson
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Publication number: 20180169307Abstract: An implantable drug eluting medical device includes a polymer substrate having a surface, a first plurality of nanofibers, and at least one antimicrobial drug. Each of the first plurality of nanofibers includes a first portion interpenetrated with the surface of the substrate to mechanically fix the nanofiber to the substrate, and a second portion projecting from the surface. The at least one antimicrobial drug is disposed within or among the second portion of the first plurality of nanofibers.Type: ApplicationFiled: December 15, 2017Publication date: June 21, 2018Inventors: Mary M. Byron, David R. Wulfman, Angelo Fruci, Adam McGraw, Danielle Frankson, Gregory J. Sherwood, Joseph T. Delaney, JR., Adeniyi O. Aremu
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Publication number: 20180169308Abstract: Disclosed herein are devices and methods for reduced pressure tissue therapy. Some variations of suction devices for reduced pressure tissue therapy comprise a housing, a suction force generating mechanism located within the housing, and a storage module configured to retain tissue exudates. In some variations, the storage module includes a sleeve configured to collect tissue exudates. The sleeve may include a support element to help maintain the lateral structural integrity of the sleeve and/or retain the cross-sectional geometry of the sleeve under negative pressure. In use, the storage module may reduce sanitary and/or biohazard risks by preventing the exudates from contacting the housing and/or suction force generating mechanism. The storage module is configured to be replaced so that the housing and suction force generating mechanism can be used for more than one session.Type: ApplicationFiled: August 16, 2016Publication date: June 21, 2018Inventors: Dean HU, Kenneth WU
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Publication number: 20180169309Abstract: A dressing (2) and an apparatus (1) comprising the dressing, for cleansing the wounds (5) in which an irrigant fluid from a reservoir (12) connected to a conformable would dressing and would exudate from the dressing are moved by a device (18) (which may be a single pump or two pumps) for moving fluid through a flow Path (6, 7, 9, 10) which passes through the dressing with a means for providing simultaneous aspiration and irrigation of the wound, to provide a desired balance of fluid at a controlled nominal flow rate that removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting would healing over the wound bed.Type: ApplicationFiled: February 12, 2018Publication date: June 21, 2018Inventors: Patrick Lewis Blott, Edward Yerbury Hartwell, Julian Lee-Webb, Derek Nicolini
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Publication number: 20180169310Abstract: A low-profile reduced pressure treatment apparatus and system are provided. The apparatus includes a moldable conduit holder, a conduit through the conduit holder, and a flexible base. The conduit holder has first and second bulkhead surfaces, a convex top surface, and a bottom surface adapted to conform to a tissue contact region adjacent to a tissue site. An end of the conduit is substantially flush with the first bulkhead surface and a longitudinal axis of the conduit is substantially perpendicular to the first and second bulkhead surfaces. The base is connected on a first side to the bottom surface of the conduit holder, and extends beyond the first bulkhead surface to form an overlay zone adjacent the first bulkhead surface. An adhesive is disposed on a second side of the flexible base to secure the flexible base to the tissue contact region.Type: ApplicationFiled: February 15, 2018Publication date: June 21, 2018Inventor: Robert Peyton WILKES
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Publication number: 20180169311Abstract: A method of recovering white blood cells from a leukoreduction filter, the method comprising providing a solution comprising a sugar, flowing a volume of the solution through a leukoreduction filter containing captured white blood cells, and collecting elute from the leukoreduction filter, wherein the elute comprises the solution and recovered white blood cells.Type: ApplicationFiled: December 1, 2017Publication date: June 21, 2018Inventors: Jo Anne B. Alfaro, Yoshikazu Mizobuchi
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Publication number: 20180169312Abstract: A heart pump assembly includes an elongate catheter with a proximal portion and a distal portion, a rotor at the distal portion of the elongate catheter, a driveshaft, and a bearing. The rotor can include an impeller blade shaped to induce fluid flow in a first axial direction. The drive shaft may be coupled to or integrally formed with a proximal end of the rotor and can include a pump element formed in a surface of the drive shaft. The bearing can include a bore into which the drive shaft extends. The pump element is shaped so as to induce fluid flow through the bore in a second axial direction which can be the same or opposite to the first axial direction.Type: ApplicationFiled: December 18, 2017Publication date: June 21, 2018Inventor: Vincent Barry
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Publication number: 20180169313Abstract: Apparatus and methods are described, including a catheter (20) configured to be placed inside a blood vessel of a subject. A first impeller (28) is disposed on the catheter, and a second impeller (28) is disposed on the catheter, proximally to the first impeller. A support structure (160) is disposed upon the catheter such that a longitudinal center of the support structure is disposed between the first and second impellers, the support structure being configured to support an inner wall of the blood vessel in an open configuration in a region between the first and second impellers. Other applications are also described.Type: ApplicationFiled: May 18, 2016Publication date: June 21, 2018Inventors: Ehud SCHWAMMENTHAL, Yosi TUVAL, Daniel GLOZMAN, Tom SHTENDEL, Gad LUBINSKY
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Publication number: 20180169314Abstract: A medical fluid delivery system in one embodiment includes: a first medical fluid delivery machine configured to generate a first message for remote transmission to a first patient or caregiver indicating (i) that the first medical fluid delivery machine is ready to perform a task or (ii) a preprogrammed time for the first medical fluid delivery machine to perform a task; and a second medical fluid delivery machine configured to generate a second message for remote transmission to a second patient or caregiver indicating (i) that the second medical fluid delivery machine is ready to perform a task or (ii) a preprogrammed time for the second medical fluid delivery machine to perform a task.Type: ApplicationFiled: December 21, 2016Publication date: June 21, 2018Inventor: Christopher Daniel Gassman
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Publication number: 20180169315Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: ApplicationFiled: May 23, 2016Publication date: June 21, 2018Inventors: Paolo ROVATTI, Alessandro SURACE, Cario Alberto LODI, Anders WALLENBORG, Anders NILLSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
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Publication number: 20180169316Abstract: A renal therapy system with cassette-based blood and dialysate pumping is disclosed. An example system includes a blood pump actuator, a dialysis fluid pump actuator, a dialysis fluid heater, a dialyzer, and a disposable unit. The example disposable unit includes a blood cassette portion configured to be operatively connected to the blood pump actuator to pump blood through the blood cassette portion. The example disposable unit also includes a dialysis fluid cassette portion, separate from the blood cassette portion, configured to be operatively connected to the dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion. The blood cassette portion and the dialysis fluid cassette portion are both in fluid communication with the dialyzer. The example disposable unit also includes a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion.Type: ApplicationFiled: February 5, 2018Publication date: June 21, 2018Inventors: Ying-Cheng Lo, Robert W. Childers, Thomas D. Kelly, Justin Rohde
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Publication number: 20180169317Abstract: A dialysis agent A including a mixture containing glucose, acetic acid, and acetate salt, but not sodium bicarbonate, wherein the molar ratio of acetic acid:acetate salt is 1:0.5 to 1:2, and wherein a total amount of the acetic acid and acetate salt contained in the dialysis agent A is between 2 mEq/L and 6 mEq/L when the dialysis agent A is dissolved in 1 L of a bicarbonate dialysate.Type: ApplicationFiled: February 20, 2018Publication date: June 21, 2018Inventors: Hiroshi NOGUCHI, Michiko MYOSE, Junya KIKUISHI, Mina HASHIMOTO, Hideyuki AOYAMA
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Publication number: 20180169318Abstract: An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure. The apparatus comprises a dilution syringe for removal of a portion of peritoneal fluid from the peritoneal cavity. A glucose bag comprises glucose concentrate at a concentration of 30 %. A small amount of glucose concentrate is mixed with the dilution fluid in the dilution syringe in order to dilute the glucose concentrate to below 3 % concentration. Then, the mixture is filled into the peritoneal cavity from the dilution syringe in order to replenish the glucose in the peritoneal cavity for maintaining a substantially constant glucose concentration in the peritoneal cavity. In addition, peritoneal fluid is intermittently removed from the peritoneal cavity for counteracting increased intraperitoneal fluid volume and increased intraperitoneal pressure due to ultrafiltration. A UF bag is arranged for receiving such surplus peritoneal fluid. A glucose syringe may be arranged for metering the glucose concentrate.Type: ApplicationFiled: August 26, 2016Publication date: June 21, 2018Applicant: TRIOMED ABInventor: Hans BENGTSSON
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Publication number: 20180169319Abstract: The present invention relates to the treatment of cancers. Specifically, the invention pertains to a method for the extracorporeal treatment of one or more body fluids (e.g., blood or cerebrospinal fluid, CSF) in two stages characterized by removing a body fluid (e.g., blood or CSF) from a living body diseased with a type of cancer, passing the body fluid through a first stage of applying a treatment to at least one antigen in the body fluid. More specifically, the treatment comprises creating an antibody-antigen moiety during passage thereof through said first stage, passing the treated body fluid through a second stage, removing antibody-antigen moiety from the body fluid during passage through the second stage, and returning the purified body fluid to the body.Type: ApplicationFiled: October 18, 2017Publication date: June 21, 2018Inventor: Mitchell S. Felder
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Publication number: 20180169320Abstract: A method controls a device for extracorporeal blood gas exchange. The device has a membrane as a gas-liquid barrier between a bloodstream and a gas stream. The membrane further makes possible a passing over of the carbon dioxide content from the bloodstream into the gas stream. The device has at least one actuator. A change in a value of an operating parameter of the actuator brings about a change in a value of the carbon dioxide content that passes over from the bloodstream into the gas stream. The method further includes providing breathing gas information that indicates a carbon dioxide concentration in breathing gas and providing a control signal, which indicates a request for setting a value of the operating parameter and changing of the value of the operating parameter as a function of the carbon dioxide concentration in the breathing gas.Type: ApplicationFiled: December 18, 2017Publication date: June 21, 2018Inventors: Henning GERDER, Karsten HILTAWSKY
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Publication number: 20180169321Abstract: A device for cleaning nasal membranes comprising a head that is inserted into a nostril. Fluid is pumped from a reservoir onto the nasal membrane. The head rotates to remove debris from the membrane. The sprayed fluid and debris is suctioned through inlets into a suction chamber.Type: ApplicationFiled: February 6, 2018Publication date: June 21, 2018Inventor: Kemi Azeez
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Publication number: 20180169322Abstract: Disclosed is a medical device component for delivering medication fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a body-mountable base unit, and a top cover assembly that is removably couplable to the base unit and to the fluid infusion device. The base unit includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base unit also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base unit, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith.Type: ApplicationFiled: December 14, 2017Publication date: June 21, 2018Inventors: Chia-Hung Chiu, Peter Schultz, Gayane R. Voskanyan, Hsifu Wang, Rebecca K. Gottlieb, Kenneth D. Warnock, Ricardo Juarez Martinez
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Publication number: 20180169323Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.Type: ApplicationFiled: February 14, 2018Publication date: June 21, 2018Inventors: R. Marie Tieck, Jacob E. Pananen, Afshin Bazargan, Juan M. Alderete, JR.
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Publication number: 20180169324Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.Type: ApplicationFiled: February 14, 2018Publication date: June 21, 2018Inventors: R. Marie Tieck, Jacob E. Pananen, Afshin Bazargan, Juan M. Alderete, JR.
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Publication number: 20180169325Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.Type: ApplicationFiled: February 14, 2018Publication date: June 21, 2018Inventors: R. Marie Tieck, Jacob E. Pananen, Afshin Bazargan, Juan M. Alderete, JR.
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Publication number: 20180169326Abstract: A power injector syringe assembly (100) that includes a syringe body (110) having a syringe barrel (120). An outer wall (126b) of the syringe barrel (120) is tapered from its proximal end (122) to its distal end (124), with the outer diameter of the syringe barrel (120) progressively increasing when proceeding in the direction of its distal end (124). When this syringe barrel (120) is disposed within a pressure sleeve (180), the clearance between the outer diameter of the syringe barrel (120) and the inner diameter of the pressure sleeve (180) is progressively reduced proceeding in the discharge direction during power injector operations.Type: ApplicationFiled: December 20, 2016Publication date: June 21, 2018Applicant: Liebel-Flarsheim Company LLCInventor: Frank M. Fago
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Publication number: 20180169327Abstract: A system for delivering fluid to a patient including housing having at least one syringe port and a fluid control device adapted to interface with and actuate at least one syringe engaged therein. The fluid control device includes a processor configured to control a fluid delivery and to wirelessly communicate with one or more portable computers. The portable computer may be programmed or configured to receive one or more fluid delivery parameters from the fluid control device, a user interface, a patient records database, an imaging device, a second computer, a server, a wireless network, or a combination thereof and generate a display containing information pertaining to the fluid delivery parameter based at least partially on the received data. The fluid control device is further configured or programmed to execute one or more control options based at least partially on instructions received from the portable computer.Type: ApplicationFiled: May 25, 2016Publication date: June 21, 2018Inventors: Barry Iddon, Michael A. Spohn, Benjamin James Cullen, Alison Ruth von Moger, Johannes Christoph Behrisch, Peter John Sprada, Richard Sokolov
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Publication number: 20180169328Abstract: The disclosure provides a drug monitoring device assembled outside an intravenous infusion set for intravenous infusion, including a fastening assembly, a monitoring sensor mounted on the fastening assembly, and a monitoring module. The monitoring sensor includes at least one turbidity light transmitter for emitting first light beams and at least one light receiver. The first light beams change in directions when passing through the intravenous infusion set. The at least one light receiver generates a first sensing signal in response to receiving one of the first light beams. The monitoring module generates a turbidity warning message when a number of the first sensing signals received during an estimation time period is greater than a turbidity warning threshold.Type: ApplicationFiled: February 13, 2017Publication date: June 21, 2018Inventors: Cheng-Yi Yang, Yi-Fei Luo
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Publication number: 20180169329Abstract: A system for occlusion detection could include a syringe pump for a syringe containing a medication, wherein the syringe includes a plunger and the syringe pump includes a plunger driver. A bendable element could be integrally formed with the plunger driver, and a force sensor could also be integrally formed with the plunger driver. Upon occurrence of an occlusion, the plunger would exert a force backwardly against the bendable element, thereby deflecting the bendable element into contact with the force sensor to thereby generate a signal indicating the occurrence of the occlusion.Type: ApplicationFiled: February 6, 2018Publication date: June 21, 2018Inventors: Jacob A. Wander, Grant A. Adams, Christopher A. Lacy
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Publication number: 20180169330Abstract: Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.Type: ApplicationFiled: February 19, 2018Publication date: June 21, 2018Inventor: Don Ludolph
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Publication number: 20180169331Abstract: Examples of determining and using physiological response estimates with glucose monitoring and insulin dosing systems and methods are disclosed. For example, one method includes receiving a selection of food items from a predefined catalog of food items as being part of a meal associated with a user profile, the catalog including nutritional information corresponding to food items in the catalog; determining nutritional information of the meal based on the nutritional information of each selected food item; receiving a notification from a user interface that a user associated with the user profile has started eating the meal; receiving successive indications of the user's glucose levels; computing a physiological response estimate associated with the user profile and the meal based on the successive indications of the user's glucose levels and the nutritional information of the meal.Type: ApplicationFiled: November 13, 2017Publication date: June 21, 2018Applicant: Verily Life Sciences LLCInventor: GANESH BALACHANDRAN
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Publication number: 20180169332Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, user input indicating an activity by the patient, obtaining historical data for the patient corresponding to the activity, determining a probable patient response corresponding to the activity based at least in part on the historical data for the patient, determining an adjustment for delivering the fluid by the infusion device based at least in part on the probable patient response, and operating the infusion device to deliver the fluid to the patient in accordance with the adjustment.Type: ApplicationFiled: December 19, 2017Publication date: June 21, 2018Inventors: Mahta Sadeghzadeh, Benyamin Grosman, David Legray, Ulrich H. Rankers, Anirban Roy, Steven J. Vargas
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Publication number: 20180169333Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, measurement values indicative of a condition of the patient provided by a sensing device, identifying an event pattern based at least in part on the measurement values for the condition and historical data associated with the patient, generating a notification indicative of the event pattern in response to identifying the event pattern, and adjusting operation of the infusion device to deliver the fluid to the patient in a manner that is influenced by the event pattern in response to receiving user input confirming the event pattern.Type: ApplicationFiled: December 19, 2017Publication date: June 21, 2018Inventors: Benyamin Grosman, David Legray, Ulrich H. Rankers, Anirban Roy, Steven J. Vargas, Mahta Sadeghzadeh
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Publication number: 20180169334Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, an input meal indication, obtaining historical data for the patient associated with the input meal indication, determining an estimated carbohydrate amount corresponding to the input meal indication based at least in part on the historical data, determining a bolus dosage of the insulin based at least in part on the estimated carbohydrate amount, and operating an actuation arrangement of the infusion device to deliver the bolus dosage of the insulin to the patient.Type: ApplicationFiled: December 19, 2017Publication date: June 21, 2018Inventors: Benyamin Grosman, Anirban Roy, Patrick E. Weydt, Neha J. Parikh, Louis J. Lintereur, Di Wu
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Publication number: 20180169335Abstract: Systems, methods, and computer-readable media for providing a decision support solution to medical professionals to optimize medical care through data monitoring and feedback treatment are provided herein. In another embodiment, a computer-implemented method for modeling patient outcomes resulting from treatment in a specific medical area includes receiving patient-specific data associated with a patient, determining a plurality of possible patient states under which the patient can be categorized, a current patient state under which the patient can be categorized and determining probabilities of the patient transitioning from any of the possible patient states to every other possible patient state.Type: ApplicationFiled: January 26, 2018Publication date: June 21, 2018Inventors: Dimitar V. Baronov, Evan J. Butler, Jesse M. Lock
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Publication number: 20180169336Abstract: An apparatus for delivering a bolus of a medical agent to a patient. The apparatus comprises a pump mechanism, a data input device, and a processor in data communication with the keypad and arranged to control the pump mechanism. The processor is programmed to receive data specifying a bolus amount through the data port, receive data regarding duration through the data port, receive a percentage through the data port, the percentage defining a portion of the bolus amount to deliver immediately upon executing a deliver command and a remainder of the bolus amount to deliver over the duration upon executing a deliver command, and execute the deliver command thereby controlling the pump mechanism to deliver the bolus. Also a method of temporarily adjusting the delivery rate of an infusion pump. The infusion pump is programmed to deliver a basal rate.Type: ApplicationFiled: February 15, 2018Publication date: June 21, 2018Inventor: Michael L. Blomquist
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Publication number: 20180169337Abstract: A device has a hollow guide shell including an injection end and a longitudinal axis. An actuator magnet is disposed in the hollow guide shell. An injection pin is coupled to the actuator magnet. A driver magnet is positioned on the device radially outward from the actuator magnet. A fluid cartridge is disposed in the injection end of the hollow guide shell, the fluid cartridge including a needle and a plunger. The driver magnet selectively exerts an injection force on the actuator magnet in a direction oriented towards the injection end of the hollow guide shell to engage the injection pin with the fluid cartridge. A liquid, gas or other agent can selectively be ejected from the cartridge by the device to inject the fluid, gas or other agent into another object.Type: ApplicationFiled: December 20, 2017Publication date: June 21, 2018Inventor: Richard C. Paschal
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Publication number: 20180169338Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support includes a supporting beam arranged on the syringe support and biased radially inwards. The supporting beam is adapted to axially bias the syringe in a distal direction within the housing. The disclosure further relates to an autoinjector.Type: ApplicationFiled: June 2, 2016Publication date: June 21, 2018Inventors: Carsten Mosebach, Thomas Mark Kemp
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Publication number: 20180169339Abstract: The housing for mounting an elongate-shaped container on an injection pen comprises an elongate-shaped body which extends along a longitudinal axis (X30) and which defines an interior volume (V32) for fully receiving the container. The body is provided, on the outside of a first axial end, with at least one first mechanical member for attaching a needle. The body is further provided, in the vicinity of a second axial end opposite the first axial end, with at least one second mechanical member for attaching the housing onto an injection pen. The housing further comprises, in the vicinity of the first axial end thereof, at least one third mechanical member for irreversibly locking a container in position, fully contained in the interior volume (V32) of the body of the housing. Said third locking member is formed by an elastically deformable tab intended to ensure locking of the container in position in the interior volume (V32) of the body of the housing, by axially retaining a flange of the container.Type: ApplicationFiled: June 1, 2016Publication date: June 21, 2018Inventor: Antoine Aneas
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Publication number: 20180169340Abstract: The method is used to produce at least one injectable-product reservoir assembly for an injection pen. The method comprises at least the sequence of steps consisting of: producing a hollow housing equipped with a first mechanical member for attaching a needle and a second mechanical member for attaching the housing onto an injection pen; inserting (F6) an elongate container having an open bottom into the housing; and filling the container with a predetermined quantity of injectable product, through an opening of the open bottom of the container.Type: ApplicationFiled: June 1, 2016Publication date: June 21, 2018Inventor: Antoine Aneas