Patents Issued in August 2, 2018
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Publication number: 20180215660Abstract: Methods for fabricating a reduced reflectance metal mesh are disclosed, including depositing a brittle layer onto a substrate; forming micro-cracks in the brittle layer; depositing a reduced reflectance layer onto the micro-cracked brittle layer; depositing a reduced reflectance layer onto the micro-cracked brittle layer; depositing a conductive material onto the reduced reflectance layer; and performing a lift-off of the brittle layer from the substrate, resulting in the reduced reflectance metal mesh atop the substrate. Other embodiments are described and claimed.Type: ApplicationFiled: January 27, 2017Publication date: August 2, 2018Applicant: 2M Technology, LLCInventor: Zhihong Liu
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Publication number: 20180215661Abstract: Curable coating compositions having a high degree of cure and high modulus upon excitation with an LED or laser source are described. The curable coating compositions include one or more radiation-curable monomers and one or more photoinitiators. The curable coating compositions are preferably devoid of oligomers. The LED or laser source preferably provides UV radiation having a peak wavelength in the range from 360 nm-410 nm.Type: ApplicationFiled: January 17, 2018Publication date: August 2, 2018Inventors: Inna Igorevna Kouzmina, Darren Andrew Stainer
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Publication number: 20180215662Abstract: A synthetic quartz glass lid for use in optical device packages is prepared by furnishing a synthetic quartz glass lid precursor comprising a synthetic quartz glass substrate (1) and a metal or metal compound film (2), and forming a metal base adhesive layer (3) on the metal or metal compound film (2). The metal or metal compound film contains Ag, Bi, and at least one element selected from P, Sb, Sn and In.Type: ApplicationFiled: January 30, 2018Publication date: August 2, 2018Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Harunobu MATSUI, Daijitsu HARADA, Masaki TAKEUCHI
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Publication number: 20180215663Abstract: The present invention relates to a method for preparing a macroporous and mesoporous geopolymer and especially a geopolymer foam, comprising the following successive steps (1) preparing a composite material comprising a geopolymer matrix and an organic liquid; then (2) eliminating said organic liquid by a treatment selected from the group consisting of heat treatment, oxidation treatment, photodegradation treatment and extraction using a supercritical fluid or ultrasounds.Type: ApplicationFiled: March 27, 2015Publication date: August 2, 2018Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: David LAMBERTIN, Arnaud POULESQUEN, Fabien FRIZON, Adrien ROOSES, Frederic GOETTMANN
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Publication number: 20180215664Abstract: A building product in the form of an internal lining board (10) made up of a mixture of hemp shiv (14) and a binder which may be clay based or lime based. The mixture is located between two layers (12) of lining paper (10).Type: ApplicationFiled: July 18, 2016Publication date: August 2, 2018Inventor: Thomas James Christopher Robinson
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Publication number: 20180215665Abstract: An encapsulated agent includes a central part and an outer part that covers a surface of the central part. The central part contains a material that is expansive with respect to a liquid, and the outer part contains a material that is able to induce expansion of the central part with respect to the liquid.Type: ApplicationFiled: August 26, 2016Publication date: August 2, 2018Applicant: ADEKA CORPORATIONInventors: Kazuyuki NODA, Masatoshi HOMMA, Kensaku AKIMOTO, Hirokatsu SHINANO
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Publication number: 20180215666Abstract: The disclosure features methods of forming composite materials, and the composite materials formed by such methods. The methods include forming a mixture that includes a binder material and a filler material, and applying a pressure of at least 10 MPa to the mixture to form the composite material, where the composite material thus formed includes less than 9% by weight of the binder material, less than 18% by volume of the binder material, or both, and has a flexural strength of at least 3 MPa.Type: ApplicationFiled: July 28, 2016Publication date: August 2, 2018Inventors: Yu Qiao, Tze Han Chen, Anh V. Le
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Publication number: 20180215667Abstract: Sintered product having a chemical analysis such that, in mass percentages: SiO2 content is greater than 0.2% and less than 2%, and CaO content is greater than 0.1% and less than 1.5%, and MgO content is less than 0.3%, and alumina and other elements being the complement at 100%, the content of other elements being less than 1.5%, having a relative density greater than 90%, comprising, for more than 90% of its volume, a stack of ceramic platelets (10) laid flat, all of said platelets having an average thickness less than 3 ?m, more than 95% by number of said platelets each containing more than 95% by mass of alumina, having a width (l) greater than 81 mm.Type: ApplicationFiled: January 30, 2018Publication date: August 2, 2018Inventors: Nassira Benameur, Christian His, Jérôme Leloup
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Publication number: 20180215668Abstract: [Problem to be Solved] Provided are an aluminum-silicon-carbide composite having high thermal conductivity, low thermal expansion, and low specific gravity and a method for producing the composite. [Solution] Provided is an aluminum-silicon-carbide composite formed by impregnating a porous silicon carbide molded body with an aluminum alloy.Type: ApplicationFiled: July 31, 2015Publication date: August 2, 2018Applicant: Denka Company LimitedInventors: Akimasa YUASA, Takeshi MIYAKAWA, Daisuke GOTO
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Publication number: 20180215669Abstract: A sintered material includes a first material and a second material, the first material being partially stabilized ZrO2 having a crystal grain boundary or crystal grain in which 5 to 90 volume % of Al2O3 is dispersed with respect to a whole of the first material, the second material including at least one of SiAlON, silicon nitride and titanium nitride, the sintered material including 1 to 50 volume % of the first material.Type: ApplicationFiled: January 5, 2017Publication date: August 2, 2018Inventors: Kentaro Chihara, Satoru Kukino, Akito Ishii
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Publication number: 20180215670Abstract: A method of fabricating a ceramic article includes providing a porous body that includes a plurality of fiber bundles that has an intra-bundle porosity and an inter-bundle porosity, infiltrating the intra-bundle porosity and the inter-bundle porosity with a mixture of particles in a liquid carrier, the particles having an average size selected with respect to at least the intra-bundle porosity, removing the liquid carrier from the porous body to deposit the particles in the intra-bundle porosity and in the inter-bundle porosity, infiltrating a preceramic polymer into a remaining intra-bundle porosity and a remaining inter-bundle porosity, and thermally converting the preceramic polymer to a ceramic material.Type: ApplicationFiled: March 29, 2018Publication date: August 2, 2018Inventors: Shahram Amini, Xia Tang, Wayde R. Schmidt, SR., Tania Bhatia Kashyap
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Publication number: 20180215671Abstract: A composite material comprising 50 to 95 mass % grains of primary material selected from the group consisting of talc, mica, graphite and hexagonal boron nitride, and 0.01 to 40 mass % fibres having a length of 0.05 to 20 mm, and a ratio of length to diameter of at least 5. The grains of the primary material have a mean size of 3 to 50 microns.Type: ApplicationFiled: August 17, 2016Publication date: August 2, 2018Applicant: ELEMENT SIX (UK) LIMITEDInventors: MOHAMMAD NAJAFI SANI, XIAOXUE ZHANG, SUCHI SUBHRA MUKHERJI
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Publication number: 20180215672Abstract: A manufacturing method of a honeycomb structure includes a forming step of forming a honeycomb formed body by use of a kneaded material containing a cordierite forming raw material, a slurry coating step of coating a coating layer forming slurry which contains a cordierite forming raw material on four regions in a rotation area when each of two straight lines passing through the center of gravity of the cross section and extending in a diagonal direction of main quadrangular cells is rotated in a range of ±x° of the center of gravity in a circumferential surface, and a firing step of firing the honeycomb formed body on which the slurry is coated. The value x is in a range of 7 to 45, and the slurry is adjusted so that the coating layer has a porosity higher than that of the honeycomb structure body as much as 5% or more.Type: ApplicationFiled: January 19, 2018Publication date: August 2, 2018Applicant: NGK INSULATORS, LTD.Inventors: Daniel Yukichi KITAGUCHI, Nobuyuki Kashiwagi
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Publication number: 20180215673Abstract: The application relates to a method for creating a pattern on a surface of a hydraulic binder-based composition, comprising applying by printing a deactivating composition (D1) or acidic composition (A1) to a part or to the whole surface of a hydraulic binder-based composition.Type: ApplicationFiled: July 28, 2016Publication date: August 2, 2018Inventors: Mathias AGNELY, Sandrine MATEO, Bruno PELLERIN
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Publication number: 20180215674Abstract: A chelated zinc adjuvant composition includes water, an effective amount of a micronutrient consisting of zinc chelated with an organic acid and an organic amine, a mono-, di- or polysaccharide and an alkyl polysaccharide. The adjuvant has a pH of up to 6.5. When admixed with a pesticide capable of precipitating with the zinc, due to the zinc being chelated, the zinc is prevented from precipitating with the pesticide and is available for uptake. When the adjuvant composition is applied in seed, soil, foliage or fruit applications, zinc uptake is improved.Type: ApplicationFiled: March 28, 2018Publication date: August 2, 2018Inventors: James Dwight Scott, Danny Brown
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Publication number: 20180215675Abstract: A strain of Gluconacetobacter diazotrophicus (Gd) characterised by the presence of at least one nucleic acid sequence selected from SEQ ID NOS 1-10 or variants or paralogues thereof and/or the presence of a single plasmid of about 17566 bp in size. Such strains, exemplified by IMI504853, are useful in agriculture, in particular as they are able to colonise plants intracellularly.Type: ApplicationFiled: July 27, 2016Publication date: August 2, 2018Inventors: David DENT, Dhaval PATEL, Gary Devine
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Publication number: 20180215676Abstract: A method for operating a composter device including directing exhaust from a composting container to a reservoir by way of a first fluid pathway, directing ambient air to the reservoir by way of a second fluid pathway, and mixing the exhaust from the first fluid pathway and the ambient air from the second fluid pathway.Type: ApplicationFiled: March 27, 2018Publication date: August 2, 2018Inventors: RACHEL MAGHAS, THOMAS ALAN LATACK
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Publication number: 20180215677Abstract: The invention relates to 5,5?-bis(2,4,6-trinitrophenyl)-2,2?-bi(1,3,4-oxadiazole) and bis(2,4,6-trinitrobenzoyl)oxalohydrazide, an energetic active mass comprising or consisting of 5,5?-bis(2,4,6-trinitrophenyl)-2,2?-bi(1,3,4-oxadiazole) and/or bis(2,4,6-trinitrobenzoyl)oxalohydrazide, a use of 5,5?-bis(2,4,6-trinitrophenyl)-2,2?-bi(1,3,4-oxadiazole) as explosive, a use of bis(2,4,6-trinitrobenzoyl)oxalohydrazide as explosive as well as methods for synthesizing 5,5?-bis(2,4,6-trinitrophenyl)-2,2?-bi(1,3,4-oxadiazole) and bis(2,4,6-trinitrobenzoyl)oxalohydrazide.Type: ApplicationFiled: October 21, 2016Publication date: August 2, 2018Inventors: Thomas Klapötke, Tomasz Grzegorz Witkowski
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Publication number: 20180215678Abstract: The invention relates to a cast explosive composition. There is provided a precure castable explosive composition comprising an explosive material, a polymerisable binder, said cross linking reagent comprising at least two reactive groups each of which is protected by a labile blocking group.Type: ApplicationFiled: July 6, 2016Publication date: August 2, 2018Applicant: BAE SYSTEMS plcInventors: REBECCA ELIZABETH STEPHENS, RICHARD STEPHEN ARTHUR, WAYNE CORD HAYES, MICHAEL EDWARD BUDD
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Publication number: 20180215679Abstract: An ignition formulation for an incendiary material is disclosed. The ignition formulation comprises an initiator capable of reacting exothermically with the incendiary material to an extent sufficient to generate a flame when contacted with the incendiary material and a non-aqueous inhibitor capable of slowing the rate of exothermic reaction between the incendiary material and the initiator, thereby providing a delay period between contact of the ignition formulation with the incendiary material and generation of the flame. The non-aqueous inhibitor may be a compound selected from a group comprising, for example, long chain (C5-C12) alcohols, alkanes, alkenes, cycloalkanes, ethers, esters, ketones, carboxylic acids, aromatic hydrocarbons, organonitrates, diesel, biodiesel, kerosene, modified kerosene and oils.Type: ApplicationFiled: March 24, 2015Publication date: August 2, 2018Applicant: Raindance Systems Pty Ltd.Inventors: Robert Andrew STEVENSON, Roger FRANKLIN
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Publication number: 20180215680Abstract: A system and method for automatic production of astatine-211 labeled molecules is described. The invention represents a significant advantage in the preparation of At-211 radiopharmaceuticals including better reproducibility, reduced production time and increased radiation safety. The invention also enables routine automatic synthesis of radiopharmaceuticals in a clinical setting, in conjunction or at short distance from a cyclotron unit capable of producing the radionuclide.Type: ApplicationFiled: June 17, 2015Publication date: August 2, 2018Inventors: Sture Lindegren, Emma Aneheim
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Publication number: 20180215681Abstract: The invention concerns a process for the dimerization of ethylene to 1-butene, carried out with a catalytic composition comprising: at least one nickel precursor with an oxidation number of (+II), at least one phosphine ligand with formula PR1R2R3 in which the groups R1, R2 and R3 may be identical or different and which may or may not be bonded together, and at least one activating agent selected from the group formed by chlorinated and brominated hydrocarbylaluminium compounds, used alone or as a mixture, said composition having a molar ratio of the phosphine ligand to the nickel precursor in the range 5 to 30 and a molar ratio of the activating agent to the phosphine ligand greater than or equal to 1.Type: ApplicationFiled: July 26, 2016Publication date: August 2, 2018Applicant: IFP Energies NouvellesInventors: Pierre-Alain BREUIL, Olivia CHAUMET-MARTIN
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Publication number: 20180215682Abstract: The present disclosure provides methods for producing hydrocarbon compounds, which may comprise directing a feed stream comprising methane (CH4) and an oxidizing agent into an oxidative coupling of methane (OCM) unit to generate from at least a portion of the CH4 and the oxidizing agent an OCM effluent comprising the hydrocarbon compounds. A portion of the OCM effluent may be directed into a recycle loop that comprises (i) a hydrogenation unit that hydrogenates at least a portion of unsaturated hydrocarbons from the additional portion of the OCM effluent, and (ii) a methanation unit that reacts hydrogen with carbon monoxide or carbon dioxide from the additional portion of the OCM effluent in a methanation reaction to form CH4. The recycle loop may output a recycle stream comprising the CH4 generated by the methanation unit. At least a portion of the recycle stream may be directed into the OCM unit.Type: ApplicationFiled: February 5, 2018Publication date: August 2, 2018Inventors: Humera A. Rafique, Srinivas Vuddagiri, Guido Radaelli, Erik C. Scher, Jarod McCormick, Joel Cizeron
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Publication number: 20180215683Abstract: A process and system is provided including hydroisomerization reaction zone for production of high octane gasoline blending components that provide high selectivity for producing high octane isomers of light paraffins. A light paraffin feed is enriched by incorporation of dissolved hydrogen, thereby permitting a reaction phase that is liquid or substantially liquid to produce high octane gasoline blending components. Accordingly, a substantially two phase isomerization reactor system is provided, with a hydrogen-enriched liquid feedstock phase and a solid phase catalyst.Type: ApplicationFiled: January 27, 2017Publication date: August 2, 2018Inventor: Omer Refa KOSEOGLU
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Publication number: 20180215684Abstract: Para-xylene is separated from a mixture of C8 aromatics using a simulated moving bed (SMB) adsorption process, wherein a MOF is used as an adsorbent and an alkane or alkene having 7 or less carbon atoms, such as hexane or heptane is used as desorbent. Because of the difference in boiling points of a hexane or heptane desorbent as compared to conventional desorbents such as toluene or para-diethylbenzene, less energy is required to separate hexane or heptane from C8 aromatics by distillation than the energy required to separate toluene or diethylbenzene from C8 aromatics by distillation.Type: ApplicationFiled: July 29, 2016Publication date: August 2, 2018Inventors: Meha RUNGTA, Jeevan S. ABICHANDANI, Dana L. PILLIOD, Robert G. TINGER, Anthony GO, Ke ZHANG, Sankar NAIR, Jason GEE, David SHOLL
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Publication number: 20180215685Abstract: In a process for separating one or more 3,3?-, 3,4?- and 4,4?-dimethyl biphenyl isomers, a feed comprising the isomers is contacted with a zeolite adsorbent which contains one or more metal cations in the +1 or +2 oxidation states. Separation processes for each of the 3,3?-, 3,4?- and 4,4?-dimethyl biphenyl isomers is provided.Type: ApplicationFiled: February 1, 2018Publication date: August 2, 2018Inventors: Changyub PAEK, Michael P. LANCI, Randall D. PARTRIDGE, Allen W. BURTON, Carla S. PEREIRA, Benjamin A. McCOOL
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Publication number: 20180215686Abstract: The presently disclosed subject matter relates to methods and systems for purifying 1,3-butadiene from a C4 hydrocarbon stream. An example method includes introducing a C4 hydrocarbon stream including 1,3-butadiene and acetlyenes to an organic azide in the presence of a catalyst to generate a first stream including triazole, separating triazole from the first stream to produce a second stream including 1,3-butadiene, and distilling 1,3-butadiene from the second stream to produce a purified 1,3-butadiene product stream.Type: ApplicationFiled: November 1, 2016Publication date: August 2, 2018Applicant: SABIC Global Technologies B.V.Inventors: Kuldeep WADHWA, Antonio MATARREDONA, Radu IGNAT, Sekhar MAMILLA, Christoph ROOSEN, Alex LONDONO
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Publication number: 20180215687Abstract: A method for the synthesis of a aryl compound of Formula (1).Type: ApplicationFiled: August 8, 2016Publication date: August 2, 2018Inventors: Ramiz Boulos, John Feutrill
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Publication number: 20180215688Abstract: The present invention is a method for producing a fluorinated hydrocarbon represented by a structural formula (3), wherein an ether compound represented by a structural formula (1) and an acid fluoride represented by a structural formula (2) are brought into contact with each other in a hydrocarbon-based solvent, in the presence of a catalyst in which boron trifluoride is supported on a metal oxide: wherein R1 and R2 represent an alkyl group having 1 to 3 carbon atoms, R3 represents a hydrogen atom, a methyl group or an ethyl group, and R4 and R5 represent a methyl group or an ethyl group; and R4 and R2 may be bonded to each other to form a cyclic structure. Through the present invention, a method for industrially advantageously producing 2-fluorobutane is provided.Type: ApplicationFiled: July 26, 2016Publication date: August 2, 2018Applicant: ZEON CORPORATIONInventor: Tatsuya SUGIMOTO
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Publication number: 20180215689Abstract: A method for isomerizing a hydrohalofluoroolefin isomer to produce a corresponding hydrohalofluoroolefin isomer includes a step contacting a composition that contains at least a hydrohalofluoroolefin isomer and that has been adjusted to 100 ppm or lower in moisture concentration, with a catalyst in a gas phase, thereby obtaining a product. This method makes it possible to suppress the catalyst performance lowering.Type: ApplicationFiled: May 27, 2016Publication date: August 2, 2018Applicant: Central Glass Company, LimitedInventors: Takamasa KITAMOTO, Satoru OKAMOTO, Masahiko TANI, Masatomi KANAI, Kohei SUMIDA
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Publication number: 20180215690Abstract: A process is disclosed for (i) producing E-1,1,1,4,4,4-hexafluoro-2-butene (E-HFO-1336mzz) from Z-1,1,1,4,4,4-hexafluoro-2-butene (Z-HFO-1336mzz), comprising the steps of (a) providing a starting material comprising Z-1,1,1,4,4,4-hexafluoro-2-butene, (b) contacting the starting material with a suitable catalyst in a reaction zone to produce E-HFO-1336mzz; and optionally, (c) recovering the E-HFO-1336mzz. The process may be performed in the gas phase or in the liquid phase and as a batch process or as a continuous process.Type: ApplicationFiled: August 4, 2016Publication date: August 2, 2018Inventors: MARIO JOSEPH NAPPA, VIACHESLAV A PETROV, SHENG PENG
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Publication number: 20180215691Abstract: The present invention provides a method for purifying a fluid comprising a first drying stage which comprises contacting a first fluid stream comprising one or more hydro(chloro)fluoroolefins and water with a source of sulphuric acid to produce a first treated fluid stream comprising the hydro(chloro)fluoroolefin(s) and a first spent sulphuric acid stream, wherein the first treated fluid stream comprises a lower concentration of water than the first fluid stream.Type: ApplicationFiled: July 14, 2016Publication date: August 2, 2018Applicants: MEXICHEM FLUOR S.A. DE C.V., MEXICHEM UK LIMITEDInventors: EMMA J HODGSON, JAMES HENRY MURRAY, GARY LLOYD
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Publication number: 20180215692Abstract: Methods, systems and catalysts for converting an alcohol containing feedstock to an upgraded material in a single catalyst bed wherein a feedstock is fed to a catalyst under preselected conditions to obtain an intermediate; and condensing the intermediate through an aldol condensation reaction to yield a product containing an upgraded material. In one instance the feedstock includes ethanol, the catalyst is a mixed metal oxide catalyst and the upgraded material is typically a C5+ ketone(s) or alcohol(s), such as 2-pentanone, 2-heptanone, 4-heptanone and 2-nonanone.Type: ApplicationFiled: January 15, 2018Publication date: August 2, 2018Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Karthikeyan Kallupalayam Ramasamy, Michel J. Gray, Carlos A. Alvarez-Vasco, Mond F. Guo, Senthil Subramaniam
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Publication number: 20180215693Abstract: Provided is a method of producing 2-hydroxy-1,4-naphthoquinone in a large amount, a high yield, and inexpensively. This method comprises oxidizing 2-hydroxynaphthalene with hydrogen peroxide in (1) an alkaline aqueous solution or in (2) a mixture of an alkaline aqueous solution with an inert organic solvent incompatible with water, in the presence of a vanadium catalyst.Type: ApplicationFiled: June 24, 2016Publication date: August 2, 2018Applicant: AGRO-KANESHO CO., LTD.Inventor: Seiji KAKINUMA
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Publication number: 20180215694Abstract: A composition comprising a compound of formula (Va) wherein n is 1 or 2 and wherein m is 1 or 2, with n and m preferably both being 1 or both being 2, more preferably both being 1, and/or, preferably and, a compound of formula, wherein n is 1 or 2 and wherein m is 1 or 2, with n and m preferably both being 1 or both being 2, more preferably both being 1, and wherein at least 90 weight-% of the composition consist of compounds of formula (Va) and formula (Vb).Type: ApplicationFiled: May 28, 2015Publication date: August 2, 2018Applicant: BASF SEInventors: Dominic RIEDEL, Joaquim Henrique TELES, Thomas WURM
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Publication number: 20180215695Abstract: The present disclosure provides quantum dot organic ligand and preparation method thereof, quantum dot structure material, quantum-dot-containing layer, and quantum-dot-containing light emitting diode. The quantum dot organic ligand have the following structure R1-(R2)n-R3, wherein R1 is a chelating group capable of chelating with a metal; R2 is a group having a conjugated electron pair, and n is a positive integer; and R3 is organic group. The conjugated electron pair structure of R2 facilitates delocalization of electrons, which can improve the transport and conduction of electrons and/or holes, thereby improving the efficiency of quantum dots and lowering the turn-on voltage.Type: ApplicationFiled: December 2, 2016Publication date: August 2, 2018Applicant: BOE TECHNOLOGY GROUP CO., LTD.Inventor: Zhuo Chen
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Publication number: 20180215696Abstract: The present invention relates to the use of molybdenum and vanadium mixed oxides, optionally iron doped, as catalysts for the oxidation of unsaturated alcohols, in particular allyl alcohol, and also to a process for the production of unsaturated carboxylic acids, in particular acrylic acid, in the gas phase, in the presence of such a catalyst.Type: ApplicationFiled: June 18, 2015Publication date: August 2, 2018Inventors: Sébastien PAUL, Benjamin KATRYNIOK, Franck DUMEIGNIL, Marcia ARAQUE MARIN, Toru MURAYAMA, Wataru UEDA
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Publication number: 20180215697Abstract: The present invention relates to a method for the stabilization of bis(oxalato) platinum (II) acid and to a device therefor.Type: ApplicationFiled: July 27, 2016Publication date: August 2, 2018Applicant: UMICORE AG & CO. KGInventors: Eileen WOERNER, Ralf KARCH, Andreas RIVAS-NASS, Angelino DOPPIU, Annika FREY
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Publication number: 20180215698Abstract: The present invention relates to a method for the purification of cadaverine from an aqueous cadaverine salt composition comprising one or more involatile impurities, the method comprising: (1) mixing the aqueous cadaverine salt composition with one or more bases to provide an aqueous cadaverine composition having a pH of at least about 12; (2) distilling or evaporating the aqueous cadaverine composition to produce an aqueous cadaverine solution, wherein one or more solvents are added to the evaporation/distillation system before the evaporation/distillation stops, and the one or more solvents comprise at least one or more high boiling point (HBP) solvents having a boiling point of at least 185° C. (1 atm); and (3) subjecting the aqueous cadaverine solution to one or more rectification steps to provide a cadaverine product.Type: ApplicationFiled: February 21, 2018Publication date: August 2, 2018Applicants: CATHAY R&D CENTER CO., LTD., CATHAY INDUSTRIAL BIOTECH LTD.Inventors: Xiucai LIU, Charlie LIU, Bingbing QIN, Naiqiang LI, Yang CHEN
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Publication number: 20180215699Abstract: The present invention relates to cationic compounds of formula (I) for use as peripheral NMDA receptor antagonists.Type: ApplicationFiled: July 26, 2016Publication date: August 2, 2018Applicants: Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance Publique-Hôpitaux De Paris, Centre National de la Recherche Scientifique (CNRS), Université Paris-SudInventors: Marc Humbert, Sylvia Cohen-Kaminsky, Sébastien Dumas, Gilles Bru-Mercier, Mouad Alami, Jean-Daniel Brion, Samir Messaoudi, Gilles Galvani
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Publication number: 20180215700Abstract: Provided herein are methods and intermediates for making (1R,2R,5R)-5-amino-2-methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathway.Type: ApplicationFiled: July 22, 2016Publication date: August 2, 2018Inventors: Terrence Joseph CONNOLLY, Hon-Wah MAN, Periyandi NAGARAJAN, Chinnapillai RAJENDIRAN, Jasti VENKATESWARLU
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Publication number: 20180215701Abstract: The invention provides bupropion analogue compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity.Type: ApplicationFiled: December 22, 2016Publication date: August 2, 2018Inventors: Frank Ivy Carroll, Bruce Edward Blough, Philip Abraham
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Publication number: 20180215702Abstract: A convenient method for converting oximes into enamides is disclosed. The process produces enamides without the concomitant production of a large volume of metallic waste. The enamides are useful precursors to amides and amines.Type: ApplicationFiled: January 29, 2018Publication date: August 2, 2018Inventors: Charles Vandenbossche, John R. Snoonian
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Publication number: 20180215703Abstract: An isolated stearoyl amino acid salt of formula (II) or formula (III) is provided, wherein M in the formula (II) is K+, Na+, or NH4+; and M2+ in the formula (III) is Ba2+, Ca2+, or Mg2+. Also provided are compositions containing the isolated stearoyl amino acid salt and methods of using the isolated stearoyl amino acid salt and composition to treat a disorder, such as cerebral ischemia, stroke, Alzheimer's disease, and Parkinson's disease.Type: ApplicationFiled: January 23, 2018Publication date: August 2, 2018Inventors: Hongzhuan CHEN, Yang LU, Jianhua LIU, Shuangqi TANG
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Publication number: 20180215704Abstract: Amides substituted with aromatic groups were synthesized and some were purified to create enantiomer pure compounds. The compounds were tested to determine their ability to inhibit the growth of bacteria and the formation of biofilms created by bacteria. Some of these compounds were found to be effective antibacterials and to effectively inhibit the formation of biofilms.Type: ApplicationFiled: January 12, 2018Publication date: August 2, 2018Applicant: Indiana University Research and Technology CorporationInventors: William L. Scott, Martin J. O'Donnell, Jack Geno Samaritoni
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Publication number: 20180215705Abstract: Novel diphenylurea and benzylbenzenesulfonamide compounds are disclosed along with methods of inhibiting the activity of TRPV1 and methods of treating pain associated with transient receptor potential vanilloid type 1 (TRPV1) using such compounds.Type: ApplicationFiled: February 5, 2016Publication date: August 2, 2018Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Xiang-Qun XIE, Zhiwei Feng
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Publication number: 20180215706Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.Type: ApplicationFiled: July 23, 2016Publication date: August 2, 2018Applicants: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Yongseok CHOI, Jae-Hong KIM, Kyeong LEE, Hyo-Kyung HAN, Jun Dong WEI, Jinsun KWON, Ja-ll GOO
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Publication number: 20180215707Abstract: The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by ROR?.Type: ApplicationFiled: March 25, 2015Publication date: August 2, 2018Applicant: Piramal Enterprises LimitedInventors: Rajiv SHARMA, Bichismita SAHU, Sunil Vasantrao MALI, Deepak SINGH
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Publication number: 20180215708Abstract: The present invention relates to a compound of formula (3Z,5S)-5-(hydroxymethyl)-1-[(2?-methyl-1,1?-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-meth19243yloxime, and/or an active metabolite thereof having antagonist action at the oxytocin receptor and/or vasopressin V1a receptor, to processes for their preparation, pharmaceutical compositions containing them and their use.Type: ApplicationFiled: March 28, 2018Publication date: August 2, 2018Inventor: Andre CHOLLET
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Publication number: 20180215709Abstract: The present invention relates to compounds that inhibit the activity of Type III deiodinase (DIO3). The present invention further relates to methods for treating or preventing depression, depression associated with other psychiatric or general medical diseases or conditions, condition amenable to treatment with known anti-depressants and cancer, particularly by using the compounds of the invention.Type: ApplicationFiled: March 16, 2015Publication date: August 2, 2018Applicants: HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD., INDIAN INSTITUTE OF SCIENCEInventors: Bernard LERER, Mugesh GOVINDASAMY, Tzuri LIFSCHYTZ