Patents Issued in August 14, 2018
  • Patent number: 10045693
    Abstract: An ophthalmologic observation apparatus of an embodiment includes a photographing optical system, measuring optical system, optical-path coupler, first and second drivers and controller. The photographing optical system includes a first focusing lens and performs photography for acquiring a front image of an eye. The measuring optical system includes a second focusing lens and performs OCT for acquiring a cross-sectional image of the eye. The optical-path coupler couples optical paths of the photographing optical system and measuring optical system at a location on the eye side than the first and second focusing lenses. The first driver moves the first focusing lens along an optical axis of the photographing optical system. The second driver moves the second focusing lens along an optical axis of the measuring optical system. The controller controls the first and second drivers individually.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: August 14, 2018
    Assignee: KABUSHIKI KAISHA TOPCON
    Inventors: Ryuichi Morishima, Kohta Fujii
  • Patent number: 10045694
    Abstract: A flexible, integrated, urine-based diagnostic device designed such that one or more diagnostic channels are integrated into the body of the device. Each diagnostic channel is designed to contain an immunoassay to detect the presence of a selected analyte so that the device can return a visible readout indicating the presence of the analyte. The flexibility of the device aids the user in the sample collection process.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: August 14, 2018
    Assignee: LIA DIAGNOSTICS, INC.
    Inventors: Bethany Ann Edwards, Frances Melina Dimare
  • Patent number: 10045695
    Abstract: The invention relates to a dental imaging apparatus which includes an x-ray imaging means and at least one color camera for photographing the face of a patient positioned at the imaging station of the apparatus, which at least one color camera is arranged to image the patient's face positioned at the patient support station from different directions, and means arranged into functional connection with said at least one color camera for creating a virtual three-dimensional texture model of the patient's face.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: August 14, 2018
    Assignee: PLANMECA OY
    Inventors: Kustaa Nyholm, Christian DeGodzinsky, Juha Koivisto
  • Patent number: 10045696
    Abstract: Fluorescent markers used to identify a tissue may be imaged in a bright environment by synchronizing the imaging process with rapidly switched ambient lighting so that imaging occurs in phase with a switching off of the ambient lighting. In this way, valuable fluorescent imaging may be performed in an environment that appears to be brightly illuminated, for example in the area of a surgical suite.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: August 14, 2018
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Thomas Mackie, Adam Uselmann, Andreas Velten, Surendra Prajapati, Kevin Eliceiri
  • Patent number: 10045697
    Abstract: A system for measuring and converting to an observer intelligible form an internal physiological parameter of a patient. The invention allows transcutaneous telemetry of intracranial pressure via a system which includes a patient implanted sensor module and an external processing module, optically coupled to the sensor module via an external coupling module. A sensor within the sensor module transduces the measured pressure and a near infrared emitter transmits the telemetry when interrogated by the external coupling module. A set of tuned inductor-crystal circuits comprised in part of a cylindrical crystal oscillator whose resonant frequency is sensed by a dipper circuit arrangement is provided. Power for the sensor module is derived inductively through rectification of a transcutaneously-applied high-frequency alternating electromagnetic field generated within the external coupling module.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: August 14, 2018
    Inventor: Erich W. Wolf, II
  • Patent number: 10045698
    Abstract: A diagnostic apparatus (20) for detecting a presence of breast cancer in a patient disposed in a testing position. The diagnostic apparatus (20) includes a housing (44) and a camera assembly (58) that is supported by the housing (44) for recording images of the breasts of the patient. A rail (76) is supported by and extends from the housing (44) and terminates at a pair of rail ends (80). A trolley (88) interconnects the camera assembly (58) and the rail (76) and is slideable along said rail (76) for providing movement of the camera assembly (58) along the rail (76) between the rail ends (80) for allowing the camera assembly (58) to consecutively record images at different positions along the rail (76) and to record images of the lymph nodes of the patient when the camera assembly (58) is disposed adjacent to the rail ends (80) in alignment with the sides of the breasts of the patient.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: August 14, 2018
    Assignee: First Sense Medical, LLC
    Inventors: Paul G. Angott, Pavan Vempaty, Steven Henke, Ajay Mudunuri
  • Patent number: 10045699
    Abstract: Often the physiological and emotional state of a person can be associated with certain cortical activity that can cause certain thermal patterns on the person's forehead. Thus, thermal measurements of the forehead may be used to differentiate between user states. In one embodiment, a system includes at least one inward-facing head-mounted thermal camera (CAM) that takes thermal measurements of at least first and second regions on the right side of a user's forehead (THR1 and THR2, respectively), and thermal measurements of at least third and fourth regions on the left side of the forehead (THL1 and THL2, respectively). The middles of the first and third regions are at least 1 cm above the middles of the second and fourth regions, respectively. The system also includes a computer that determines, based on THR1, THR2, THL1, and THL2, whether the user is in a normal state or an abnormal state.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 14, 2018
    Assignee: Facense Ltd.
    Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
  • Patent number: 10045700
    Abstract: A blood pressure estimating method includes measuring a biosignal including pulse wave information of a user, determining a calibration method for a blood pressure estimation model, calibrating the blood pressure estimation model using the determined calibration method, and estimating a blood pressure of the user from the biosignal using the calibrated blood pressure estimation model.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: August 14, 2018
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Seungwoo Noh, Taesung Jung, Younho Kim, Sangyun Park
  • Patent number: 10045701
    Abstract: Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: August 14, 2018
    Assignee: Pacesetter, Inc.
    Inventor: Stuart O. Schecter
  • Patent number: 10045702
    Abstract: The present invention relates to a device (12) for obtaining a vital sign of a subject (14), comprising an interface (22) for receiving a set of image frames (24) of a subject (14), a signal extraction unit (26) for extracting a photoplethysmographic (PPG) signal of the subject (14) from said set of image frames (24), a signal evaluation unit (28) for determining a feature of said PPG signal indicative of the information content of the extracted PPG signal with respect to a desired vital sign of the subject (14), a processing unit (30) for determining a binning configuration based on the determined feature of the extracted PPG signal, said binning configuration being provided for controlling binning of image pixels of an image frame; and a vital signs determination unit (32) for determining vital sign information from the extracted PPG signal.
    Type: Grant
    Filed: September 28, 2014
    Date of Patent: August 14, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Vincent Jeanne, Hendrikus Petrus Maria Sterken
  • Patent number: 10045703
    Abstract: An embodiment in accordance with the present invention provides a system and method for imaging living tissue and processing laser speckle data anisotropically to calculate laser speckle contrast preferentially along the direction of blood flow. In the present invention, raw laser speckle images are obtained and processed resulting in the anisotropic laser speckle images. The system and method involve the determination of the direction of blood flow for every pixel within the region of interest (primary pixel) and subsequent extraction of a set of secondary pixels in the spatio-temporal neighborhood of the primary pixel that is anisotropic in the direction of blood flow. Speckle contrast is then calculated for every primary pixel as the ratio of standard deviation and mean of all secondary pixels in this anisotropic neighborhood and collectively plotted using a suitable color mapping scheme to obtain an anisotropic laser speckle contrast image of the region of interest.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: August 14, 2018
    Assignee: The Johns Hopkins University
    Inventors: Abhiskek Rege, Janaka Senarathna, Nitish V. Thakor
  • Patent number: 10045704
    Abstract: A surgical method aids identification of nerves in a body to help prevent damage to the nerves during surgery to the body proximate the nerves. An electrode introduced to within a body cavity through a catheter is placed proximate a nerve within the body cavity by a laparoscopic or robotic device. An exploratory probe placed in the body cavity is selectively placed along a presumed pathway of the nerve to provide an electrical signal through the nerve to the electrode. An analyzer interfaced with the electrode analyzes the electrical signal received at the electrode to determine the proximity of the exploratory probe to the nerve, allowing mapping of the nerve pathway through the body cavity.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: August 14, 2018
    Assignee: ProPep, LLC
    Inventors: Randy Fagin, Jon Schiff, Jann Bonfils-Rasmussen
  • Patent number: 10045705
    Abstract: Disclosed is a hand-held, medical, multi-channel biological information acquisition mobile terminal system, comprising two signal sensing gloves RL with a cable end embedded therein, for use in acquiring a variety of biological signals comprising multi-channel interconnected ECG, heart sounds, finger blood volume pulse, and skin impedance etc., the signal sensing gloves RL also comprising a signal acquisition device S, a signal transmission device C connected to the signal acquisition device S, and a mobile terminal T connected wirelessly or with a wired connection. The system has the characteristics of low power consumption, small size, low cost and fewer control channels needed for multi-channel connection; and the system can achieve on-site acquisition of a variety of biological information and the mobile function of electronic health records.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: August 14, 2018
    Assignee: DONGGUAN MATHEMATICAL ENGINEERING ACADEMY OF CHINESE MEDICINE AND GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE AND GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
    Inventors: Zhiwei Liang, Zhangjin Su, Lili He, Xiaoping Lai
  • Patent number: 10045706
    Abstract: A catheter with a film composite structure. The catheter at least includes a polymer film that is shaped such that a first polymer film layer, which is arranged inwardly relative to the catheter, and a second polymer film layer, which is arranged outwardly relative to the catheter, are produced; one or more electrodes arranged at least partially on an outer surface of the film composite structure; and a conductor structure, which includes conductive tracks for the electrical connection of the electrodes and which is arranged at least in part between the first and second polymer film layers. An associated production method for the catheter is also contemplated herein.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: August 14, 2018
    Assignee: VascoMed GmbH
    Inventors: Wolfgang Geistert, Daniel Schulze
  • Patent number: 10045707
    Abstract: Cardiac catheterization is performed with a catheter having a basket-shaped assembly at its distal end. A plurality of spline electrodes are disposed on the splines of the assembly. The assembly is configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body. A far-field electrode is disposed in the interior of the assembly. An intracardiac electrogram and a far-field electrogram are obtained with at least one of the spline electrodes and the far-field electrode, respectively. The far-field component is removed from the intracardiac electrogram using the far-field electrogram.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: August 14, 2018
    Assignee: Biosense Webster (Israel) Ltd.
    Inventor: Assaf Govari
  • Patent number: 10045708
    Abstract: A wearable device configured to acquire and process electrocardiographic measurements, detect lead inversion and correct the acquired measurements for lead inversion is provided. In one example, the wearable device can detect lead inversion by first assessing whether the P-wave of a given electrocardiographic measurement has a negative amplitude, and if the P-wave is found to be negative, the device can determine if the magnitude of the R-wave is smaller than the maximum of the magnitudes of the S-wave and the Q-wave. In another example, the device can be put through an enrollment procedure in which electrocardiographic measurements are taken with the device being worn at known locations on the body. Once the enrollment procedure is completed, when the device is being used, any electrocardiographic results obtained can be compared against the measurements taken during the enrollment phase, and the location of the device on the body can be determined.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: August 14, 2018
    Assignee: Apple Inc.
    Inventor: Sorin V. Dusan
  • Patent number: 10045709
    Abstract: A system and method for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (ECG) data over a set time period. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: August 14, 2018
    Assignee: Bardy Diagnostics, Inc.
    Inventors: Gust H. Bardy, Ezra M. Dreisbach
  • Patent number: 10045710
    Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 14, 2018
    Assignee: Medtronic, Inc.
    Inventors: Elise J. Higgins, Mark L. Brown, Jian Cao
  • Patent number: 10045711
    Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: August 14, 2018
    Assignee: NociMed, Inc.
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
  • Patent number: 10045712
    Abstract: A patient table adapted for use in association with an MR scanner for neonatal infants is provided. The patient table has an extendable patient bed attached to and extendable from the patient table. The patient bed may be at least partially inserted into an MR scanner without requiring the patient table to enter the MR scanner. A transport mechanism is on the underside of the patient table so that it may be readily moved over the floor on which it rests. The patient table includes a latching mechanism that may operate to releasably attach the patient table to a patient table docking assembly. The docking assembly is operative to selectively move the patient table towards, into and away from the MR scanner.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: August 14, 2018
    Assignee: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventor: Charles L. Dumoulin
  • Patent number: 10045713
    Abstract: Systems and methods described herein use near field communications to locate a radiating transponder, such as a pill swallowed by a patient. The system can be triggered to turn on and transmit a waveform to a set of antennas attached to, coupled with, or near the patient. The magnetic field emitted by the transponder can be measured by the receiving antennas, for example, using principles of mutual inductance. The differential phase and/or time shifts between the antennas can contain sufficient information to find the location of the transponder and optionally its orientation relative to body coordinates. The system can display the location and/or orientation of the transponder. Further, the pill can include a reservoir to deliver a payload at a particular site of the patient's body based at least in part on the determined location.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: August 14, 2018
    Assignee: Rock West Medical Devices, LLC
    Inventors: Thomas Eugene Old, John Christopher Baker, Neal Jay Carron, Donald Gordon Pritchett
  • Patent number: 10045714
    Abstract: The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro-stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: August 14, 2018
    Assignees: RGB Medical Devices S.A., Fundació Eurecat
    Inventors: José Javier Rodiera Olivé, Antonio González Martínez, Francisco Javier Corral Herranz, Ricardo Ruiz Nolasco
  • Patent number: 10045715
    Abstract: A patient support apparatus includes detectors and a controller operable to automatically update a tare weight for use in determining a true patient weight. The detectors are configured to produce signals indicating a presence or absence of a corresponding removable component. The controller is configured to determine weights of each and every removable component on the patient support apparatus and store each weight in a memory. The controller is further configured to receive the signals produced by the detectors and detect any addition or removal of removable components of the patient support apparatus, update the tare weight, and determine a weight of a patient being supported on the patient support apparatus.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 14, 2018
    Assignee: Hill-Rom Services, Inc.
    Inventors: Brian J Hoffman, Mike J Viltro, Chris L Hildenbrand, James L Walke, Aziz A Bhai, Eric R Meyer, David C Newkirk, Frank Sauser, Nicole Johannigman, Brandon P Fisk
  • Patent number: 10045716
    Abstract: Various patient monitoring systems can include a sensor configured to collect three dimensional information. The systems can identify a location of a patient support surface based on the three dimensional information. The systems can set a two dimensional planar threshold based on the patient support surface. The systems can identify a patient location above the patient support surface based on the three dimensional information and compare the patient location to the two dimensional planar threshold. Exceeding the threshold can be indicative of a high risk of a patient fall. An alert can be generated based on the threshold being exceeded. The systems can repeat the identification of the patient support surface location and the setting of the threshold to account for changes in the patient area.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: August 14, 2018
    Assignee: CareView Communications, Inc.
    Inventors: Matt Clark, Derek del Carpio, Kenneth Chapman
  • Patent number: 10045717
    Abstract: The disclosed embodiments relate to the design of a system that identifies a person. During operation, the system receives channel state information (CSI) for a set of orthogonal frequency division modulation (OFDM) subcarriers while the person moves in a region that includes two or more nodes that use the set of OFDM subcarriers to communicate with one another. Next, the system analyzes the CSI to obtain an analysis result. The system then determines the identity of the person based on the analysis result.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: August 14, 2018
    Assignee: The Regents of the University of California
    Inventors: Prasant Mohapatra, Parth H. Pathak, Yunze Zeng
  • Patent number: 10045718
    Abstract: A wearable sensor vehicle with a bio-input sensor and a processor. When the vehicle is worn, the sensor is arranged so as to sense bio-input from the user. The sensor senses bio-input, the processor compares the bio-input to a standard, and if the standard is met the processor indicates a response. The user may be uniquely identified from the bio-input. One or more systems on or communicating with the vehicle may be controlled transparently, without requiring direct action by the user. Control actions may include security identification of the user, logging in to accounts or programs, setting preferences, etc. The sensor collects bio-input substantially without instruction or dedicated action from the user; the processor compares bio-input against the standard substantially without instruction or dedicated action from the user; and the processor generates and/or implements a response based on the bio-input substantially without instruction or dedicated action from the user.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: August 14, 2018
    Assignee: Atheer, Inc.
    Inventors: Allen Yang Yang, Mohamed Nabil Hajj Chehade, Sina Fateh, Sleiman Itani
  • Patent number: 10045719
    Abstract: In a special mode, an internal body portion is imaged under a first white light beam to obtain a first frame composed of blue, green, and red signals. Sequentially, the body portion is imaged under a second white light beam to obtain a second frame composed of blue, green, and red signals. An oxygen saturation level is calculated from the signals. A special image is produced based on the oxygen saturation level. A displacement between the first and second frames is calculated from the signals. If the displacement is a first allowable value or more and less than a second allowable value, the special image is displayed with a lower chroma on a monitor, as compared with a case where the displacement is less than the first allowable value. If the displacement is the second allowable value or more, the special image is converted into a gray scale image.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: August 14, 2018
    Assignee: FUJIFILM Corporation
    Inventor: Takaaki Saito
  • Patent number: 10045720
    Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.
    Type: Grant
    Filed: October 15, 2016
    Date of Patent: August 14, 2018
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh
  • Patent number: 10045721
    Abstract: Systems, apparatuses and methods may provide for a transmit circuit including a light source and a receive circuit including a photodetector and a transimpedance amplifier (TIA) coupled to the photodetector. Additionally, a calibration circuit may be coupled to the transmit circuit and the receive circuit, wherein the calibration circuit includes a current controller to set an operational current of the light source to a minimum value that results in a target output voltage of the receive circuit. In one example, the gain of the TIA remains substantially constant during calibration of the receive circuit.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 14, 2018
    Assignee: Intel Corporation
    Inventors: Mohammad U. Abbasi, Sendill K. Gnanaeswaran, Nicholas P. Cowley
  • Patent number: 10045722
    Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: August 14, 2018
    Assignee: Profusa, Inc.
    Inventors: Gregory J. Kintz, William McMillan, Natalie Wisniewski
  • Patent number: 10045723
    Abstract: Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: August 14, 2018
    Assignee: DexCom, Inc.
    Inventors: Robert J. Boock, Chris W. Dring
  • Patent number: 10045724
    Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: August 14, 2018
    Assignee: Magnolia Medical Technologies, Inc.
    Inventor: Richard G. Patton
  • Patent number: 10045725
    Abstract: A capillary chamber for performing chemical and physical analysis using a plurality of whole blood samples is presented. Following a loading of the whole blood samples into a plastic tube, the whole blood samples are distributed into a collection chamber and the capillary chamber has means of adding respective vaccines or similar biological products into each capillary tubes. The whole blood is then analyzed using standard microscopic techniques with sufficient resolution and contrast to record the chemical and physical properties of the blood immediately after withdrawal.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: August 14, 2018
    Inventor: Hugh Califf
  • Patent number: 10045726
    Abstract: Described herein are systems and methods for selecting a stressor based on thermal measurements. In one embodiment, a system includes an inward-facing head-mounted thermal camera (CAM) and a computer. CAM takes thermal measurements of a region on a periorbital area (THROI1) of the user. The computer detects extents of stress based on THROI1, receives indications of potential stressors to which the user was exposed while THROI1 were taken, and selects the stressor, from among the potential stressors, based on the indications and the extents. Optionally, during most of the time the user was affected by the stressor, the effect of the stressor, as manifested via changes to THROI1, was higher than the effects of most of the potential stressors. Optionally, thermal measurements of other regions on the face may also be utilized to detect the extents of stress.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 14, 2018
    Assignee: Facense Ltd.
    Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
  • Patent number: 10045727
    Abstract: A non-transitory computer-readable recording medium stores a program that causes a computer to execute a process including: first setting an arousal section including from a time point when a subject has got on a vehicle to a time point when a predetermined time has elapsed thereafter; determining whether an arousal level of the subject has moved toward arousal in a section which is temporally later than the arousal section, based on a biosignal detected from the subject; when the arousal level has moved toward arousal in the section which is temporally later than the arousal section, updating the arousal section with a section in which the arousal level has moved toward arousal; and second setting a threshold value for determining whether the subject is in an arousal state, based on a statistical value of the subject's arousal levels corresponding to the updated arousal section.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: August 14, 2018
    Assignee: FUJITSU LIMITED
    Inventors: Yasuhiko Nakano, Satoshi Sano
  • Patent number: 10045728
    Abstract: Methods and systems for identifying blobs, for example kidney glomeruli, are disclosed. A raw image may be smoothed via a difference of Gaussians filter, and a Hessian analysis may be conducted on the smoothed image to mark glomeruli candidates. Exemplary candidate features are identified, such as average intensity AT, likelihood of blobness RT, and flatness ST. A clustering algorithm may be utilized to post prune the glomeruli candidates.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: August 14, 2018
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Teresa Wu, Min Zhang
  • Patent number: 10045729
    Abstract: The present invention relates to the estimation of the vertical in humans using an experimental design that incorporates virtual reality. Methods of measuring the perceived vertical in a subject using steady state and transient experiments are disclosed. The inventive methods are useful for diagnosis, as well as for follow up after patient rehabilitation.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: August 14, 2018
    Assignee: Laboratorio de Otoneurologia
    Inventors: Hamlet Suarez, Alejo Suarez, Dario Geisinger, Nicolas Fernandez Tournier
  • Patent number: 10045730
    Abstract: The disclosure provides for easy, reliable, and rapid screening of a mild traumatic brain injury (mTBI) based on a modeling of a subject's tracking of a dynamic target during the course of a simple motor tracking task. The gathered tracking data can be used to calculate tracking errors between the subject's actual input (e.g., grip force) and the intended target input. The tracking errors may be used to generate numerical values for model parameters that correlate the subject's responses to the tracking errors during the course of the dynamic motor tracking task. A classification model may be used to compare the model values to multi-subject model values of known diagnoses for mTBI. The entire screening process can be effectively administered in a matter of minutes or less, and with a high degree of accuracy.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: August 14, 2018
    Assignee: The MITRE Corporation
    Inventors: Michael S. Fine, Matthew Shields Caywood
  • Patent number: 10045731
    Abstract: An apparatus for detecting cervical cancer comprising, a mechanical structure configured to expose cervical region comprising, a first duck-billed blade forming a hollow cylinder at one end and a second duck-billed blade coupled to the first blade to form part of a speculum, in that the cervical region is exposed through circular area of the hollow cylinder, a pair of “L” shaped rods attached to the hollow cylinder of the first blade such that they are diagonally opposite and symmetric on either side of the exposed cervical region, and a detachable holder with a housing to hold a secondary unit and at least a pair of hooks to mount on the “L” shaped rods, the secondary unit further comprising, a camera for capturing an image of the exposed cervical region, a processor and a visual indicator to determine and indicate presence or absence of the cervix cancer from the image.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: August 14, 2018
    Assignee: M/S MANIPAL UNIVERSITY
    Inventors: Keerthana Prasad, Shyamala Guruvare, Suma Nair, Harishchandra Hebbar N, Vidya Kudva, Roopa Hegde
  • Patent number: 10045732
    Abstract: Concepts and technologies are disclosed herein for measuring user exertion via bone conduction. According to one aspect, a device can generate a measurement signal. The device can cause a transducer to transmit the measurement signal through a body of a user. The device can receive, via the transducer, a modified measurement signal. The modified measurement signal can include the measurement signal as modified by the body of the user. The device can compare the modified measurement signal to a modified baseline signal. The device can determine, based on a result of comparing the modified measurement signal to the modified baseline signal, a level of exertion experienced by the user while the measurement signal was transmitted through the body of the user.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: August 14, 2018
    Assignee: AT&T Intellectual Property I, L.P.
    Inventors: Christopher Baldwin, Brian S. Amento
  • Patent number: 10045733
    Abstract: According to one embodiment, a sleep sensor which is attached to a user who is sleeping when it is to be used is provided. The sleep sensor includes a first detector, an estimation module, a second detector and a control module. The first detector is configured to detect an acceleration signal representing acceleration that is obtained from the sleep sensor. The estimation module is configured to estimate the user's body position based on the detected acceleration signal. The second detector is configured to detect a signal for estimating a state other than the user's body position. The control module is configured to operate the second detector when the estimated user's body position is at least one of predefined body positions.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: August 14, 2018
    Assignee: TDK CORPORATION
    Inventors: Junya Takakura, Kanako Nakayama, Yasunobu Yamauchi
  • Patent number: 10045734
    Abstract: A console includes a weighing subsystem responsive to a first fluid source and a urine collection chamber. A pump infuses fluid from the first fluid source into a patient. A processing subsystem is responsive to the weighing subsystem. Based on the weight of the first fluid source and of the urine collection chamber, urine output and amount of fluid infused into the patient from the first fluid source are determined. A user can set a desired fluid balance and the amount of at least one additional fluid delivered. An actual fluid balance is calculated based on the determined urine output, the determined amount of fluid infused from the first fluid source, and the set amount of the additional fluid delivered. The pump is controlled based on actual fluid balance and set desired fluid balance so actual fluid balance becomes the same or approximately the same as the desired fluid balance.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: August 14, 2018
    Assignee: PLC Medical Systems, Inc.
    Inventors: J. Ricardo Da Silva, Wieslaw Gronek, Andrew V. Halpert, Robert I. Rudko, Mark Tauscher
  • Patent number: 10045735
    Abstract: Technologies for the sensing of biofeedback signals of a user include a body area network (BAN) system comprising one or more biofeedback sensors and one or more BAN controllers. The biofeedback sensors are configured to sense BAN signals, which may include biofeedback signals and body-coupled communication (BCC) signals. To facilitate communication, the biofeedback sensors may demultiplex the sensed BAN signals into biofeedback signals and incoming BCC signals. Similarly, the biofeedback sensors may multiplex outgoing BCC signals with sensed biofeedback signals. The BAN controller may communicate in a similar manner. Additionally, the BAN controller may process incoming BCC signals and provide feedback to the user based on BCC signals received from the biofeedback sensors.
    Type: Grant
    Filed: September 27, 2014
    Date of Patent: August 14, 2018
    Assignee: Intel Corporation
    Inventors: Nicholas P. Cowley, Ruchir Saraswat, Richard J. Goldman
  • Patent number: 10045736
    Abstract: A method for determining a status of a user utilizing wireless earpieces includes performing sensor measurements of a user utilizing at least optical sensors of the wireless earpieces, wherein the optical sensors detect metabolic abnormalities of the user, analyzing the sensor measurements, determining the status of the user utilizing at least sensor measurements from the optical sensors of the wireless earpieces, and communicating an alert to the user in response to there being a change in the status of the user. A wireless earpiece or set of wireless earpieces with optical sensors for detecting metabolic abnormalities are also provided.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: August 14, 2018
    Inventor: Peter Vincent Boesen
  • Patent number: 10045737
    Abstract: In order to enable collection of data from a head-mounted inward-facing camera, a clip-on device is attached to eyeglasses. The clip-on device optionally weighs less than 40 g and includes: (i) a body that may be attached and detached, multiple times, from a pair of eyeglasses in order to secure and release the clip-on device from the eyeglasses, (ii) an inward-facing camera fixed to the body, and (iii) a wireless communication module fixed to the body.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 14, 2018
    Assignee: Facense Ltd.
    Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
  • Patent number: 10045738
    Abstract: The disclosure describes tissue resistance measurement techniques. To avoid errors caused by bandwidth limitations of the amplifier that amplifies a signal used to determine the tissue resistance, the disclosure describes determining values at different frequencies, where the values include respective error values. The respective error values are proportional to the respective frequencies, and based on this relationship the error value can be removed from the tissue resistance measurement.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: August 14, 2018
    Assignee: Medtronic Bakken Research Center B.V.
    Inventors: Wouter Hubert Martha Adelaïde Bracke, Jeroen Jacob Arnold Tol, Egbertus Johannes Maria Bakker
  • Patent number: 10045739
    Abstract: Method and apparatus for receiving a first signal from a first working electrode of a glucose sensor positioned at a first predetermined position under the skin layer, receiving a second signal from a second working electrode of the glucose sensor positioned at a second predetermined position under the skin layer, the second signal received substantially contemporaneous to receiving the first signal, detecting a dropout in the signal level associated with one of the first or second signals, comparing the first signal and the second signal to determine a variation between the first and second signals, and confirming one of the first or second signals as a valid glucose sensor signal output when the determined variation between the first and the second signals is less than a predetermined threshold level are provided.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: August 14, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Gary Alan Hayter, John Charles Mazza, Kenneth J. Doniger
  • Patent number: 10045740
    Abstract: In some embodiments, a method, apparatus, and a system for sensing a force are provided. The apparatus may comprise a plurality of sensors configured to detect an impact force. The plurality of sensors may be arranged into a housing, such as a sports helmet. The apparatus also includes a controller operatively coupled to the plurality of sensors. The controller is adapted to: receive a signal from at least one of the plurality of sensors; determine whether a value of the signal exceeds a threshold; perform a responsive action in response to a determination that the value of signal exceeds the threshold. The responsive action comprises providing a warning, performing a logging function, and/or performing a counteraction.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: August 14, 2018
    Inventor: Jaison C. John
  • Patent number: 10045741
    Abstract: Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: August 14, 2018
    Assignee: The General Hospital Corporation
    Inventors: Matthew Tisdall, Andre van der Kouwe
  • Patent number: 10045742
    Abstract: A method for preventing infection by a virus includes obtaining a sample from a person, assaying the sample to determine whether the person has been previously infected with a predetermined virus, and if the person has not been previously infected with the virus, providing the person with a sensor positioned to detect when a person's hand approaches a predetermined distance from the person's face. By warning the person of undesired hand-to-face contacts, the person is able to reduce the incidence of related viral infections.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: August 14, 2018
    Inventors: Katherine Rose Kovarik, Joseph E. Kovarik, Mourad Zarouri