Patents Issued in August 14, 2018
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Patent number: 10045693Abstract: An ophthalmologic observation apparatus of an embodiment includes a photographing optical system, measuring optical system, optical-path coupler, first and second drivers and controller. The photographing optical system includes a first focusing lens and performs photography for acquiring a front image of an eye. The measuring optical system includes a second focusing lens and performs OCT for acquiring a cross-sectional image of the eye. The optical-path coupler couples optical paths of the photographing optical system and measuring optical system at a location on the eye side than the first and second focusing lenses. The first driver moves the first focusing lens along an optical axis of the photographing optical system. The second driver moves the second focusing lens along an optical axis of the measuring optical system. The controller controls the first and second drivers individually.Type: GrantFiled: September 12, 2013Date of Patent: August 14, 2018Assignee: KABUSHIKI KAISHA TOPCONInventors: Ryuichi Morishima, Kohta Fujii
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Patent number: 10045694Abstract: A flexible, integrated, urine-based diagnostic device designed such that one or more diagnostic channels are integrated into the body of the device. Each diagnostic channel is designed to contain an immunoassay to detect the presence of a selected analyte so that the device can return a visible readout indicating the presence of the analyte. The flexibility of the device aids the user in the sample collection process.Type: GrantFiled: March 27, 2017Date of Patent: August 14, 2018Assignee: LIA DIAGNOSTICS, INC.Inventors: Bethany Ann Edwards, Frances Melina Dimare
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Patent number: 10045695Abstract: The invention relates to a dental imaging apparatus which includes an x-ray imaging means and at least one color camera for photographing the face of a patient positioned at the imaging station of the apparatus, which at least one color camera is arranged to image the patient's face positioned at the patient support station from different directions, and means arranged into functional connection with said at least one color camera for creating a virtual three-dimensional texture model of the patient's face.Type: GrantFiled: April 3, 2017Date of Patent: August 14, 2018Assignee: PLANMECA OYInventors: Kustaa Nyholm, Christian DeGodzinsky, Juha Koivisto
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Patent number: 10045696Abstract: Fluorescent markers used to identify a tissue may be imaged in a bright environment by synchronizing the imaging process with rapidly switched ambient lighting so that imaging occurs in phase with a switching off of the ambient lighting. In this way, valuable fluorescent imaging may be performed in an environment that appears to be brightly illuminated, for example in the area of a surgical suite.Type: GrantFiled: July 19, 2013Date of Patent: August 14, 2018Assignee: Wisconsin Alumni Research FoundationInventors: Thomas Mackie, Adam Uselmann, Andreas Velten, Surendra Prajapati, Kevin Eliceiri
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Patent number: 10045697Abstract: A system for measuring and converting to an observer intelligible form an internal physiological parameter of a patient. The invention allows transcutaneous telemetry of intracranial pressure via a system which includes a patient implanted sensor module and an external processing module, optically coupled to the sensor module via an external coupling module. A sensor within the sensor module transduces the measured pressure and a near infrared emitter transmits the telemetry when interrogated by the external coupling module. A set of tuned inductor-crystal circuits comprised in part of a cylindrical crystal oscillator whose resonant frequency is sensed by a dipper circuit arrangement is provided. Power for the sensor module is derived inductively through rectification of a transcutaneously-applied high-frequency alternating electromagnetic field generated within the external coupling module.Type: GrantFiled: January 22, 2014Date of Patent: August 14, 2018Inventor: Erich W. Wolf, II
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Patent number: 10045698Abstract: A diagnostic apparatus (20) for detecting a presence of breast cancer in a patient disposed in a testing position. The diagnostic apparatus (20) includes a housing (44) and a camera assembly (58) that is supported by the housing (44) for recording images of the breasts of the patient. A rail (76) is supported by and extends from the housing (44) and terminates at a pair of rail ends (80). A trolley (88) interconnects the camera assembly (58) and the rail (76) and is slideable along said rail (76) for providing movement of the camera assembly (58) along the rail (76) between the rail ends (80) for allowing the camera assembly (58) to consecutively record images at different positions along the rail (76) and to record images of the lymph nodes of the patient when the camera assembly (58) is disposed adjacent to the rail ends (80) in alignment with the sides of the breasts of the patient.Type: GrantFiled: March 13, 2015Date of Patent: August 14, 2018Assignee: First Sense Medical, LLCInventors: Paul G. Angott, Pavan Vempaty, Steven Henke, Ajay Mudunuri
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Patent number: 10045699Abstract: Often the physiological and emotional state of a person can be associated with certain cortical activity that can cause certain thermal patterns on the person's forehead. Thus, thermal measurements of the forehead may be used to differentiate between user states. In one embodiment, a system includes at least one inward-facing head-mounted thermal camera (CAM) that takes thermal measurements of at least first and second regions on the right side of a user's forehead (THR1 and THR2, respectively), and thermal measurements of at least third and fourth regions on the left side of the forehead (THL1 and THL2, respectively). The middles of the first and third regions are at least 1 cm above the middles of the second and fourth regions, respectively. The system also includes a computer that determines, based on THR1, THR2, THL1, and THL2, whether the user is in a normal state or an abnormal state.Type: GrantFiled: December 6, 2017Date of Patent: August 14, 2018Assignee: Facense Ltd.Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
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Patent number: 10045700Abstract: A blood pressure estimating method includes measuring a biosignal including pulse wave information of a user, determining a calibration method for a blood pressure estimation model, calibrating the blood pressure estimation model using the determined calibration method, and estimating a blood pressure of the user from the biosignal using the calibrated blood pressure estimation model.Type: GrantFiled: January 27, 2016Date of Patent: August 14, 2018Assignee: Samsung Electronics Co., Ltd.Inventors: Seungwoo Noh, Taesung Jung, Younho Kim, Sangyun Park
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Patent number: 10045701Abstract: Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.Type: GrantFiled: November 6, 2012Date of Patent: August 14, 2018Assignee: Pacesetter, Inc.Inventor: Stuart O. Schecter
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Patent number: 10045702Abstract: The present invention relates to a device (12) for obtaining a vital sign of a subject (14), comprising an interface (22) for receiving a set of image frames (24) of a subject (14), a signal extraction unit (26) for extracting a photoplethysmographic (PPG) signal of the subject (14) from said set of image frames (24), a signal evaluation unit (28) for determining a feature of said PPG signal indicative of the information content of the extracted PPG signal with respect to a desired vital sign of the subject (14), a processing unit (30) for determining a binning configuration based on the determined feature of the extracted PPG signal, said binning configuration being provided for controlling binning of image pixels of an image frame; and a vital signs determination unit (32) for determining vital sign information from the extracted PPG signal.Type: GrantFiled: September 28, 2014Date of Patent: August 14, 2018Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Vincent Jeanne, Hendrikus Petrus Maria Sterken
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Patent number: 10045703Abstract: An embodiment in accordance with the present invention provides a system and method for imaging living tissue and processing laser speckle data anisotropically to calculate laser speckle contrast preferentially along the direction of blood flow. In the present invention, raw laser speckle images are obtained and processed resulting in the anisotropic laser speckle images. The system and method involve the determination of the direction of blood flow for every pixel within the region of interest (primary pixel) and subsequent extraction of a set of secondary pixels in the spatio-temporal neighborhood of the primary pixel that is anisotropic in the direction of blood flow. Speckle contrast is then calculated for every primary pixel as the ratio of standard deviation and mean of all secondary pixels in this anisotropic neighborhood and collectively plotted using a suitable color mapping scheme to obtain an anisotropic laser speckle contrast image of the region of interest.Type: GrantFiled: September 26, 2012Date of Patent: August 14, 2018Assignee: The Johns Hopkins UniversityInventors: Abhiskek Rege, Janaka Senarathna, Nitish V. Thakor
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Patent number: 10045704Abstract: A surgical method aids identification of nerves in a body to help prevent damage to the nerves during surgery to the body proximate the nerves. An electrode introduced to within a body cavity through a catheter is placed proximate a nerve within the body cavity by a laparoscopic or robotic device. An exploratory probe placed in the body cavity is selectively placed along a presumed pathway of the nerve to provide an electrical signal through the nerve to the electrode. An analyzer interfaced with the electrode analyzes the electrical signal received at the electrode to determine the proximity of the exploratory probe to the nerve, allowing mapping of the nerve pathway through the body cavity.Type: GrantFiled: November 4, 2011Date of Patent: August 14, 2018Assignee: ProPep, LLCInventors: Randy Fagin, Jon Schiff, Jann Bonfils-Rasmussen
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Patent number: 10045705Abstract: Disclosed is a hand-held, medical, multi-channel biological information acquisition mobile terminal system, comprising two signal sensing gloves RL with a cable end embedded therein, for use in acquiring a variety of biological signals comprising multi-channel interconnected ECG, heart sounds, finger blood volume pulse, and skin impedance etc., the signal sensing gloves RL also comprising a signal acquisition device S, a signal transmission device C connected to the signal acquisition device S, and a mobile terminal T connected wirelessly or with a wired connection. The system has the characteristics of low power consumption, small size, low cost and fewer control channels needed for multi-channel connection; and the system can achieve on-site acquisition of a variety of biological information and the mobile function of electronic health records.Type: GrantFiled: September 10, 2012Date of Patent: August 14, 2018Assignee: DONGGUAN MATHEMATICAL ENGINEERING ACADEMY OF CHINESE MEDICINE AND GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE AND GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINEInventors: Zhiwei Liang, Zhangjin Su, Lili He, Xiaoping Lai
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Patent number: 10045706Abstract: A catheter with a film composite structure. The catheter at least includes a polymer film that is shaped such that a first polymer film layer, which is arranged inwardly relative to the catheter, and a second polymer film layer, which is arranged outwardly relative to the catheter, are produced; one or more electrodes arranged at least partially on an outer surface of the film composite structure; and a conductor structure, which includes conductive tracks for the electrical connection of the electrodes and which is arranged at least in part between the first and second polymer film layers. An associated production method for the catheter is also contemplated herein.Type: GrantFiled: June 3, 2014Date of Patent: August 14, 2018Assignee: VascoMed GmbHInventors: Wolfgang Geistert, Daniel Schulze
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Patent number: 10045707Abstract: Cardiac catheterization is performed with a catheter having a basket-shaped assembly at its distal end. A plurality of spline electrodes are disposed on the splines of the assembly. The assembly is configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body. A far-field electrode is disposed in the interior of the assembly. An intracardiac electrogram and a far-field electrogram are obtained with at least one of the spline electrodes and the far-field electrode, respectively. The far-field component is removed from the intracardiac electrogram using the far-field electrogram.Type: GrantFiled: March 7, 2017Date of Patent: August 14, 2018Assignee: Biosense Webster (Israel) Ltd.Inventor: Assaf Govari
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Patent number: 10045708Abstract: A wearable device configured to acquire and process electrocardiographic measurements, detect lead inversion and correct the acquired measurements for lead inversion is provided. In one example, the wearable device can detect lead inversion by first assessing whether the P-wave of a given electrocardiographic measurement has a negative amplitude, and if the P-wave is found to be negative, the device can determine if the magnitude of the R-wave is smaller than the maximum of the magnitudes of the S-wave and the Q-wave. In another example, the device can be put through an enrollment procedure in which electrocardiographic measurements are taken with the device being worn at known locations on the body. Once the enrollment procedure is completed, when the device is being used, any electrocardiographic results obtained can be compared against the measurements taken during the enrollment phase, and the location of the device on the body can be determined.Type: GrantFiled: April 15, 2016Date of Patent: August 14, 2018Assignee: Apple Inc.Inventor: Sorin V. Dusan
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Patent number: 10045709Abstract: A system and method for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (ECG) data over a set time period. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.Type: GrantFiled: August 8, 2016Date of Patent: August 14, 2018Assignee: Bardy Diagnostics, Inc.Inventors: Gust H. Bardy, Ezra M. Dreisbach
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Patent number: 10045710Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.Type: GrantFiled: March 30, 2016Date of Patent: August 14, 2018Assignee: Medtronic, Inc.Inventors: Elise J. Higgins, Mark L. Brown, Jian Cao
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Patent number: 10045711Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.Type: GrantFiled: May 20, 2016Date of Patent: August 14, 2018Assignee: NociMed, Inc.Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
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Patent number: 10045712Abstract: A patient table adapted for use in association with an MR scanner for neonatal infants is provided. The patient table has an extendable patient bed attached to and extendable from the patient table. The patient bed may be at least partially inserted into an MR scanner without requiring the patient table to enter the MR scanner. A transport mechanism is on the underside of the patient table so that it may be readily moved over the floor on which it rests. The patient table includes a latching mechanism that may operate to releasably attach the patient table to a patient table docking assembly. The docking assembly is operative to selectively move the patient table towards, into and away from the MR scanner.Type: GrantFiled: August 24, 2012Date of Patent: August 14, 2018Assignee: CHILDREN'S HOSPITAL MEDICAL CENTERInventor: Charles L. Dumoulin
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Patent number: 10045713Abstract: Systems and methods described herein use near field communications to locate a radiating transponder, such as a pill swallowed by a patient. The system can be triggered to turn on and transmit a waveform to a set of antennas attached to, coupled with, or near the patient. The magnetic field emitted by the transponder can be measured by the receiving antennas, for example, using principles of mutual inductance. The differential phase and/or time shifts between the antennas can contain sufficient information to find the location of the transponder and optionally its orientation relative to body coordinates. The system can display the location and/or orientation of the transponder. Further, the pill can include a reservoir to deliver a payload at a particular site of the patient's body based at least in part on the determined location.Type: GrantFiled: March 24, 2015Date of Patent: August 14, 2018Assignee: Rock West Medical Devices, LLCInventors: Thomas Eugene Old, John Christopher Baker, Neal Jay Carron, Donald Gordon Pritchett
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Patent number: 10045714Abstract: The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro-stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.Type: GrantFiled: June 23, 2016Date of Patent: August 14, 2018Assignees: RGB Medical Devices S.A., Fundació EurecatInventors: José Javier Rodiera Olivé, Antonio González Martínez, Francisco Javier Corral Herranz, Ricardo Ruiz Nolasco
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Patent number: 10045715Abstract: A patient support apparatus includes detectors and a controller operable to automatically update a tare weight for use in determining a true patient weight. The detectors are configured to produce signals indicating a presence or absence of a corresponding removable component. The controller is configured to determine weights of each and every removable component on the patient support apparatus and store each weight in a memory. The controller is further configured to receive the signals produced by the detectors and detect any addition or removal of removable components of the patient support apparatus, update the tare weight, and determine a weight of a patient being supported on the patient support apparatus.Type: GrantFiled: April 25, 2016Date of Patent: August 14, 2018Assignee: Hill-Rom Services, Inc.Inventors: Brian J Hoffman, Mike J Viltro, Chris L Hildenbrand, James L Walke, Aziz A Bhai, Eric R Meyer, David C Newkirk, Frank Sauser, Nicole Johannigman, Brandon P Fisk
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Patent number: 10045716Abstract: Various patient monitoring systems can include a sensor configured to collect three dimensional information. The systems can identify a location of a patient support surface based on the three dimensional information. The systems can set a two dimensional planar threshold based on the patient support surface. The systems can identify a patient location above the patient support surface based on the three dimensional information and compare the patient location to the two dimensional planar threshold. Exceeding the threshold can be indicative of a high risk of a patient fall. An alert can be generated based on the threshold being exceeded. The systems can repeat the identification of the patient support surface location and the setting of the threshold to account for changes in the patient area.Type: GrantFiled: January 18, 2017Date of Patent: August 14, 2018Assignee: CareView Communications, Inc.Inventors: Matt Clark, Derek del Carpio, Kenneth Chapman
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Patent number: 10045717Abstract: The disclosed embodiments relate to the design of a system that identifies a person. During operation, the system receives channel state information (CSI) for a set of orthogonal frequency division modulation (OFDM) subcarriers while the person moves in a region that includes two or more nodes that use the set of OFDM subcarriers to communicate with one another. Next, the system analyzes the CSI to obtain an analysis result. The system then determines the identity of the person based on the analysis result.Type: GrantFiled: June 1, 2017Date of Patent: August 14, 2018Assignee: The Regents of the University of CaliforniaInventors: Prasant Mohapatra, Parth H. Pathak, Yunze Zeng
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Patent number: 10045718Abstract: A wearable sensor vehicle with a bio-input sensor and a processor. When the vehicle is worn, the sensor is arranged so as to sense bio-input from the user. The sensor senses bio-input, the processor compares the bio-input to a standard, and if the standard is met the processor indicates a response. The user may be uniquely identified from the bio-input. One or more systems on or communicating with the vehicle may be controlled transparently, without requiring direct action by the user. Control actions may include security identification of the user, logging in to accounts or programs, setting preferences, etc. The sensor collects bio-input substantially without instruction or dedicated action from the user; the processor compares bio-input against the standard substantially without instruction or dedicated action from the user; and the processor generates and/or implements a response based on the bio-input substantially without instruction or dedicated action from the user.Type: GrantFiled: November 22, 2013Date of Patent: August 14, 2018Assignee: Atheer, Inc.Inventors: Allen Yang Yang, Mohamed Nabil Hajj Chehade, Sina Fateh, Sleiman Itani
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Patent number: 10045719Abstract: In a special mode, an internal body portion is imaged under a first white light beam to obtain a first frame composed of blue, green, and red signals. Sequentially, the body portion is imaged under a second white light beam to obtain a second frame composed of blue, green, and red signals. An oxygen saturation level is calculated from the signals. A special image is produced based on the oxygen saturation level. A displacement between the first and second frames is calculated from the signals. If the displacement is a first allowable value or more and less than a second allowable value, the special image is displayed with a lower chroma on a monitor, as compared with a case where the displacement is less than the first allowable value. If the displacement is the second allowable value or more, the special image is converted into a gray scale image.Type: GrantFiled: October 23, 2012Date of Patent: August 14, 2018Assignee: FUJIFILM CorporationInventor: Takaaki Saito
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Patent number: 10045720Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.Type: GrantFiled: October 15, 2016Date of Patent: August 14, 2018Assignee: ABBOTT DIABETES CARE INC.Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh
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Patent number: 10045721Abstract: Systems, apparatuses and methods may provide for a transmit circuit including a light source and a receive circuit including a photodetector and a transimpedance amplifier (TIA) coupled to the photodetector. Additionally, a calibration circuit may be coupled to the transmit circuit and the receive circuit, wherein the calibration circuit includes a current controller to set an operational current of the light source to a minimum value that results in a target output voltage of the receive circuit. In one example, the gain of the TIA remains substantially constant during calibration of the receive circuit.Type: GrantFiled: March 30, 2016Date of Patent: August 14, 2018Assignee: Intel CorporationInventors: Mohammad U. Abbasi, Sendill K. Gnanaeswaran, Nicholas P. Cowley
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Patent number: 10045722Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.Type: GrantFiled: March 6, 2014Date of Patent: August 14, 2018Assignee: Profusa, Inc.Inventors: Gregory J. Kintz, William McMillan, Natalie Wisniewski
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Patent number: 10045723Abstract: Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.Type: GrantFiled: November 17, 2014Date of Patent: August 14, 2018Assignee: DexCom, Inc.Inventors: Robert J. Boock, Chris W. Dring
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Patent number: 10045724Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.Type: GrantFiled: December 5, 2017Date of Patent: August 14, 2018Assignee: Magnolia Medical Technologies, Inc.Inventor: Richard G. Patton
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Patent number: 10045725Abstract: A capillary chamber for performing chemical and physical analysis using a plurality of whole blood samples is presented. Following a loading of the whole blood samples into a plastic tube, the whole blood samples are distributed into a collection chamber and the capillary chamber has means of adding respective vaccines or similar biological products into each capillary tubes. The whole blood is then analyzed using standard microscopic techniques with sufficient resolution and contrast to record the chemical and physical properties of the blood immediately after withdrawal.Type: GrantFiled: May 13, 2016Date of Patent: August 14, 2018Inventor: Hugh Califf
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Patent number: 10045726Abstract: Described herein are systems and methods for selecting a stressor based on thermal measurements. In one embodiment, a system includes an inward-facing head-mounted thermal camera (CAM) and a computer. CAM takes thermal measurements of a region on a periorbital area (THROI1) of the user. The computer detects extents of stress based on THROI1, receives indications of potential stressors to which the user was exposed while THROI1 were taken, and selects the stressor, from among the potential stressors, based on the indications and the extents. Optionally, during most of the time the user was affected by the stressor, the effect of the stressor, as manifested via changes to THROI1, was higher than the effects of most of the potential stressors. Optionally, thermal measurements of other regions on the face may also be utilized to detect the extents of stress.Type: GrantFiled: December 6, 2017Date of Patent: August 14, 2018Assignee: Facense Ltd.Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
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Patent number: 10045727Abstract: A non-transitory computer-readable recording medium stores a program that causes a computer to execute a process including: first setting an arousal section including from a time point when a subject has got on a vehicle to a time point when a predetermined time has elapsed thereafter; determining whether an arousal level of the subject has moved toward arousal in a section which is temporally later than the arousal section, based on a biosignal detected from the subject; when the arousal level has moved toward arousal in the section which is temporally later than the arousal section, updating the arousal section with a section in which the arousal level has moved toward arousal; and second setting a threshold value for determining whether the subject is in an arousal state, based on a statistical value of the subject's arousal levels corresponding to the updated arousal section.Type: GrantFiled: March 8, 2016Date of Patent: August 14, 2018Assignee: FUJITSU LIMITEDInventors: Yasuhiko Nakano, Satoshi Sano
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Patent number: 10045728Abstract: Methods and systems for identifying blobs, for example kidney glomeruli, are disclosed. A raw image may be smoothed via a difference of Gaussians filter, and a Hessian analysis may be conducted on the smoothed image to mark glomeruli candidates. Exemplary candidate features are identified, such as average intensity AT, likelihood of blobness RT, and flatness ST. A clustering algorithm may be utilized to post prune the glomeruli candidates.Type: GrantFiled: March 28, 2016Date of Patent: August 14, 2018Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Teresa Wu, Min Zhang
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Patent number: 10045729Abstract: The present invention relates to the estimation of the vertical in humans using an experimental design that incorporates virtual reality. Methods of measuring the perceived vertical in a subject using steady state and transient experiments are disclosed. The inventive methods are useful for diagnosis, as well as for follow up after patient rehabilitation.Type: GrantFiled: October 6, 2011Date of Patent: August 14, 2018Assignee: Laboratorio de OtoneurologiaInventors: Hamlet Suarez, Alejo Suarez, Dario Geisinger, Nicolas Fernandez Tournier
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Patent number: 10045730Abstract: The disclosure provides for easy, reliable, and rapid screening of a mild traumatic brain injury (mTBI) based on a modeling of a subject's tracking of a dynamic target during the course of a simple motor tracking task. The gathered tracking data can be used to calculate tracking errors between the subject's actual input (e.g., grip force) and the intended target input. The tracking errors may be used to generate numerical values for model parameters that correlate the subject's responses to the tracking errors during the course of the dynamic motor tracking task. A classification model may be used to compare the model values to multi-subject model values of known diagnoses for mTBI. The entire screening process can be effectively administered in a matter of minutes or less, and with a high degree of accuracy.Type: GrantFiled: September 11, 2014Date of Patent: August 14, 2018Assignee: The MITRE CorporationInventors: Michael S. Fine, Matthew Shields Caywood
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Patent number: 10045731Abstract: An apparatus for detecting cervical cancer comprising, a mechanical structure configured to expose cervical region comprising, a first duck-billed blade forming a hollow cylinder at one end and a second duck-billed blade coupled to the first blade to form part of a speculum, in that the cervical region is exposed through circular area of the hollow cylinder, a pair of “L” shaped rods attached to the hollow cylinder of the first blade such that they are diagonally opposite and symmetric on either side of the exposed cervical region, and a detachable holder with a housing to hold a secondary unit and at least a pair of hooks to mount on the “L” shaped rods, the secondary unit further comprising, a camera for capturing an image of the exposed cervical region, a processor and a visual indicator to determine and indicate presence or absence of the cervix cancer from the image.Type: GrantFiled: June 22, 2016Date of Patent: August 14, 2018Assignee: M/S MANIPAL UNIVERSITYInventors: Keerthana Prasad, Shyamala Guruvare, Suma Nair, Harishchandra Hebbar N, Vidya Kudva, Roopa Hegde
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Patent number: 10045732Abstract: Concepts and technologies are disclosed herein for measuring user exertion via bone conduction. According to one aspect, a device can generate a measurement signal. The device can cause a transducer to transmit the measurement signal through a body of a user. The device can receive, via the transducer, a modified measurement signal. The modified measurement signal can include the measurement signal as modified by the body of the user. The device can compare the modified measurement signal to a modified baseline signal. The device can determine, based on a result of comparing the modified measurement signal to the modified baseline signal, a level of exertion experienced by the user while the measurement signal was transmitted through the body of the user.Type: GrantFiled: September 10, 2014Date of Patent: August 14, 2018Assignee: AT&T Intellectual Property I, L.P.Inventors: Christopher Baldwin, Brian S. Amento
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Patent number: 10045733Abstract: According to one embodiment, a sleep sensor which is attached to a user who is sleeping when it is to be used is provided. The sleep sensor includes a first detector, an estimation module, a second detector and a control module. The first detector is configured to detect an acceleration signal representing acceleration that is obtained from the sleep sensor. The estimation module is configured to estimate the user's body position based on the detected acceleration signal. The second detector is configured to detect a signal for estimating a state other than the user's body position. The control module is configured to operate the second detector when the estimated user's body position is at least one of predefined body positions.Type: GrantFiled: June 24, 2015Date of Patent: August 14, 2018Assignee: TDK CORPORATIONInventors: Junya Takakura, Kanako Nakayama, Yasunobu Yamauchi
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Patent number: 10045734Abstract: A console includes a weighing subsystem responsive to a first fluid source and a urine collection chamber. A pump infuses fluid from the first fluid source into a patient. A processing subsystem is responsive to the weighing subsystem. Based on the weight of the first fluid source and of the urine collection chamber, urine output and amount of fluid infused into the patient from the first fluid source are determined. A user can set a desired fluid balance and the amount of at least one additional fluid delivered. An actual fluid balance is calculated based on the determined urine output, the determined amount of fluid infused from the first fluid source, and the set amount of the additional fluid delivered. The pump is controlled based on actual fluid balance and set desired fluid balance so actual fluid balance becomes the same or approximately the same as the desired fluid balance.Type: GrantFiled: January 14, 2010Date of Patent: August 14, 2018Assignee: PLC Medical Systems, Inc.Inventors: J. Ricardo Da Silva, Wieslaw Gronek, Andrew V. Halpert, Robert I. Rudko, Mark Tauscher
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Patent number: 10045735Abstract: Technologies for the sensing of biofeedback signals of a user include a body area network (BAN) system comprising one or more biofeedback sensors and one or more BAN controllers. The biofeedback sensors are configured to sense BAN signals, which may include biofeedback signals and body-coupled communication (BCC) signals. To facilitate communication, the biofeedback sensors may demultiplex the sensed BAN signals into biofeedback signals and incoming BCC signals. Similarly, the biofeedback sensors may multiplex outgoing BCC signals with sensed biofeedback signals. The BAN controller may communicate in a similar manner. Additionally, the BAN controller may process incoming BCC signals and provide feedback to the user based on BCC signals received from the biofeedback sensors.Type: GrantFiled: September 27, 2014Date of Patent: August 14, 2018Assignee: Intel CorporationInventors: Nicholas P. Cowley, Ruchir Saraswat, Richard J. Goldman
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Patent number: 10045736Abstract: A method for determining a status of a user utilizing wireless earpieces includes performing sensor measurements of a user utilizing at least optical sensors of the wireless earpieces, wherein the optical sensors detect metabolic abnormalities of the user, analyzing the sensor measurements, determining the status of the user utilizing at least sensor measurements from the optical sensors of the wireless earpieces, and communicating an alert to the user in response to there being a change in the status of the user. A wireless earpiece or set of wireless earpieces with optical sensors for detecting metabolic abnormalities are also provided.Type: GrantFiled: June 29, 2017Date of Patent: August 14, 2018Inventor: Peter Vincent Boesen
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Patent number: 10045737Abstract: In order to enable collection of data from a head-mounted inward-facing camera, a clip-on device is attached to eyeglasses. The clip-on device optionally weighs less than 40 g and includes: (i) a body that may be attached and detached, multiple times, from a pair of eyeglasses in order to secure and release the clip-on device from the eyeglasses, (ii) an inward-facing camera fixed to the body, and (iii) a wireless communication module fixed to the body.Type: GrantFiled: December 6, 2017Date of Patent: August 14, 2018Assignee: Facense Ltd.Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
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Patent number: 10045738Abstract: The disclosure describes tissue resistance measurement techniques. To avoid errors caused by bandwidth limitations of the amplifier that amplifies a signal used to determine the tissue resistance, the disclosure describes determining values at different frequencies, where the values include respective error values. The respective error values are proportional to the respective frequencies, and based on this relationship the error value can be removed from the tissue resistance measurement.Type: GrantFiled: November 25, 2015Date of Patent: August 14, 2018Assignee: Medtronic Bakken Research Center B.V.Inventors: Wouter Hubert Martha Adelaïde Bracke, Jeroen Jacob Arnold Tol, Egbertus Johannes Maria Bakker
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Patent number: 10045739Abstract: Method and apparatus for receiving a first signal from a first working electrode of a glucose sensor positioned at a first predetermined position under the skin layer, receiving a second signal from a second working electrode of the glucose sensor positioned at a second predetermined position under the skin layer, the second signal received substantially contemporaneous to receiving the first signal, detecting a dropout in the signal level associated with one of the first or second signals, comparing the first signal and the second signal to determine a variation between the first and second signals, and confirming one of the first or second signals as a valid glucose sensor signal output when the determined variation between the first and the second signals is less than a predetermined threshold level are provided.Type: GrantFiled: March 23, 2015Date of Patent: August 14, 2018Assignee: Abbott Diabetes Care Inc.Inventors: Gary Alan Hayter, John Charles Mazza, Kenneth J. Doniger
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Patent number: 10045740Abstract: In some embodiments, a method, apparatus, and a system for sensing a force are provided. The apparatus may comprise a plurality of sensors configured to detect an impact force. The plurality of sensors may be arranged into a housing, such as a sports helmet. The apparatus also includes a controller operatively coupled to the plurality of sensors. The controller is adapted to: receive a signal from at least one of the plurality of sensors; determine whether a value of the signal exceeds a threshold; perform a responsive action in response to a determination that the value of signal exceeds the threshold. The responsive action comprises providing a warning, performing a logging function, and/or performing a counteraction.Type: GrantFiled: March 13, 2017Date of Patent: August 14, 2018Inventor: Jaison C. John
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Patent number: 10045741Abstract: Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.Type: GrantFiled: August 1, 2014Date of Patent: August 14, 2018Assignee: The General Hospital CorporationInventors: Matthew Tisdall, Andre van der Kouwe
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Patent number: 10045742Abstract: A method for preventing infection by a virus includes obtaining a sample from a person, assaying the sample to determine whether the person has been previously infected with a predetermined virus, and if the person has not been previously infected with the virus, providing the person with a sensor positioned to detect when a person's hand approaches a predetermined distance from the person's face. By warning the person of undesired hand-to-face contacts, the person is able to reduce the incidence of related viral infections.Type: GrantFiled: June 28, 2016Date of Patent: August 14, 2018Inventors: Katherine Rose Kovarik, Joseph E. Kovarik, Mourad Zarouri