Patents Issued in August 14, 2018
  • Patent number: 10047300
    Abstract: A novel process for metal content reduction of hydrocarbon oil is disclosed, which is primarily aimed at reduction of vanadium and nickel. The process uses electricity to accelerate the demetallation process, but only the flow of electrons of the electric current is used to expedite the reaction, instead of the electrolysis effect of the electric current. The process is carried out by adding inter-phase surface active reagent and phase transfer catalyst at a relatively low temperature range of 80 to 200° C. and achieves metal content reduction for vanadium and nickel. Aqueous phase alcoholic derivatives of amine solution is treated with hydrogen sulfide, carbon dioxide, etc. by additive reaction to render it more suitable for carrying more electric current and make them more active for metal reduction.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: August 14, 2018
    Assignee: INDIAN OIL CORPORATION LTD.
    Inventors: Madhusudan Sau, Ganesh Vitthalrao Butley, Yamini Gupta, Karumanchi Ramesh, Mainak Sarkar, Arangarasu Arun, Saeed Ahmed, Brijesh Kumar, Ravinder Kumar Malhotra
  • Patent number: 10047301
    Abstract: Disclosed herein are methods for resolving emulsions formed from oils present in quench waters of ethylene manufacturing operations. The methods include adding a cationic oligomer to the base of a water quench tower having an emulsion formed therein, and collecting a water phase therefrom. The water phase can be applied to a water recycling loop within the manufacturing facility.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: August 14, 2018
    Assignees: ECOLAB USA INC., SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Fabrice Cuoq, Steven Leen, Jerome Vachon, Anthoni van Zijl, Ian Robson, Roy van Lier, Theodore C. Arnst
  • Patent number: 10047302
    Abstract: Compositions consisting of block copolymers ?,?-di-aryl or alkyl sulfonates of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w of bis-ammonium and block copolymers ?,?-di-amine of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w, are provided that are effective in the dewatering and desalting crude oils whose specific gravities are within the range of 14 to 20° API. A method of dewatering and desalting heavy crude oil adds a mixture of the copolymer bifunctionalized with an aliphatic or aromatic secondary amine and a copolymer bifunctionalized with an aliphatic or aromatic tertiary amine.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: August 14, 2018
    Assignee: INSTITUTO MEXICANO DEL PETROLEO
    Inventors: Eugenio Alejandro Flores Oropeza, Cesar Andres Flores Sandoval, Reyna Reyes Martinez, Jose Gonzalo Hernandez Cortez, Alfonso Lopez Ortega, Laura Veronica Castro Sotelo, Fernando Alvarez Ramirez, Arquimedes Estrada Martinez, Flavio Salvador Vazquez Moreno
  • Patent number: 10047303
    Abstract: A system including a controller configured to receive feedback from at least one sensor configured to monitor a fluid flow of a hydrocarbon extraction system. The fluid flow includes water and an injected chemical. Additionally, the controller is configured to determine a ratio of the injected chemical to water in the fluid flow.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: August 14, 2018
    Assignee: ONESUBSEA IP UK LIMITED
    Inventors: Rolf Rustad, Harald Solheim, Gro Merete Alendal
  • Patent number: 10047304
    Abstract: Hydrogenation catalysts for aromatic hydrogenation including an organosilica material support, which is a polymer comprising independent units of a monomer of Formula [Z1OZ2OSiCH2]3 (I), wherein each Z1 and Z2 independently represent a hydrogen atom, a C1-C4 alkyl group or a bond to a silicon atom of another monomer; and at least one catalyst metal are provided herein. Methods of making the hydrogenation catalysts and processes of using, e.g., aromatic hydrogenation, the hydrogenation catalyst are also provided herein.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: August 14, 2018
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Paul Podsiadlo, Quanchang Li, David Charles Calabro, Jean Willem Lodewijk Beeckman, Lei Zhang, Kiara M. Benitez, Matthew Scott Ide, Stephen John McCarthy, Mobae Afeworki, Simon Christopher Weston, Preeti Kamakoti, Matu J. Shah, Wenyih Frank Lai, Meghan Nines, David A. Griffin, Ivy D. Johnson
  • Patent number: 10047305
    Abstract: A method for producing hydrocarbon solvents having a sulfur content of less than 10 ppm, aromatic hydrocarbon content of less than 500 ppm, an initial boiling point higher than or equal to 300° C. and final boiling point lower than or equal to 500° C., for a fraction interval of a maximum of 100° C., and pour point lower than ?25° C. according to the standard ASTM D5950, comprising of the following steps of: dewaxing of a hydrocarbon fraction having initial boiling point higher than 300° C. derived from the distillation of a gas oil fraction, hydrodearomatization of all or part of the dewaxed effluent, in the presence of a catalyst comprising nickel on an alumina base, at a pressure ranging from 60 to 200 bar and a temperature ranging from 80° C. to 250° C., recovery of the dewaxed and dearomatized fraction, distillation in fractions of the dewaxed and dearomatized fraction, recovery of at least one 300° C.+ fraction having pour point lower than ?25° C.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: August 14, 2018
    Assignee: TOTAL MARKETING SERVICES
    Inventors: Christine Aubry, Giacomo Grasso, Jean-Pierre Dath
  • Patent number: 10047306
    Abstract: The invention relates to membrane gas separation, in particular to a method of fractionating mixtures of low molecular weight hydrocarbons based on the capillary condensation of the mixture components in the pores of microporous membranes having uniform porosity and a pore diameter of 5 to 250 nm, wherein, for capillary condensation, the temperature of the membrane and the pressure on the permeate side are kept below the temperature and the pressure of the feed mixture. The method provides significantly increasing membrane permeability with respect to condensable components, and also component separation factors, while also allowing to avoid deep cooling of the gas stream fed to a membrane module, and to carry out gas separation under insignificant cooling of the membrane on the permeate side (down to -50° C.). The invention provides for energy-efficient fractionation of hydrocarbon mixtures, including separation and drying of natural and associated petroleum gases.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: August 14, 2018
    Assignee: Rosneft Oil Company
    Inventors: Andrey Anatolievich Eliseev, Dmitriy Igorevich Petukhov, Artem Anatolievich Eliseev, Viktor Andreevich Brotcman, Alexey Viktorovich Lukashin
  • Patent number: 10047307
    Abstract: A gasification system including: a casing defining: a solid material inlet; a fixed bed drying zone proximal the solid material inlet; a fixed bed pyrolysis zone arranged below the drying zone along a gravity vector, distal the solid material inlet across the pyrolysis zone; a kinetic bed combustion zone surrounded by the pyrolysis zone; and a fluidization channel extending through the drying zone and pyrolysis zone and fluidly connected to the combustion zone, the fluidization channel defining a kinetic bed reduction zone fluidly isolated from and thermally connected to the pyrolysis zone and the drying zone by the fluidization channel.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: August 14, 2018
    Assignee: All Power Labs, Inc.
    Inventor: James Mason
  • Patent number: 10047308
    Abstract: A gasifier system for reducing the particle size of non-gas byproducts of the gasification process. The gasifier system generally includes a grinder that permits uninterrupted syngas flow during gasification of biomass that contains high amounts of silica and/or salts. The described system and method incorporates a grinder that breaks apart the resultant non-gas byproducts into finer particles that may be flushed out of a gasifier using the syngas stream. The particles may then be easily separated from the gas stream in a separator and collected in a char or waste bin for removal/disposal.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: August 14, 2018
    Assignee: Ag Energy Solutions, Inc.
    Inventors: Philip W. Appel, Thomas D. Weir, Jacob M. Culley, Sarah E. Love, Daniel A. Howard
  • Patent number: 10047309
    Abstract: A method for making high density fuels including, providing pure cyclic hydrocarbons or a mixture of cyclic hydrocarbons, subjecting the cyclic hydrocarbons or mixture of cyclic hydrocarbons to electrochemical cycloaddition in the presence of at least one catalyst to generate multicyclic oligomers, and purifying the multicyclic oligomer to yield a high density fuel.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: August 14, 2018
    Assignee: The United States of America as Represented by the Secretary of the Navy
    Inventor: Benjamin G Harvey
  • Patent number: 10047310
    Abstract: The present invention provides a method for separating high purity methane gas from biogas, which comprises the steps of: compressing and cooling biogas (step 1); and separating carbon dioxide by introducing the biogas compressed and cooled in step 1 into a four-stage polymer separation membrane system in which the residue stream of the first polymer separation membrane is connected to the second polymer separation membrane, the residue stream of the second polymer separation membrane is connected to the third polymer separation membrane, and the permeate stream of the second polymer separation membrane is connected to the fourth polymer separation membrane (step 2).
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: August 14, 2018
    Assignee: Korea Research Institute of Chemical Technology
    Inventor: Jeong Hoon Kim
  • Patent number: 10047311
    Abstract: Gas hydrate slurry formation systems are provided. The gas hydrate slurry formation system includes a cavitation chamber configured to receive a fluid and a cavitation device placed within the cavitation chamber. The cavitation device is configured to form a plurality of bubbles within the fluid in the cavitation chamber. The gas hydrate slurry formation system also includes a gas inlet configured to introduce a gas within the cavitation chamber such that the gas is entrained in the plurality of bubbles to form a plurality of gas-entrained bubbles. The plurality of gas-entrained bubbles implode within the cavitation chamber to form a gas hydrate slurry.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: August 14, 2018
    Assignee: INDIAN INSTITUTE OF TECHNOLOGY MADRAS
    Inventor: Jitendra Sangwai
  • Patent number: 10047312
    Abstract: A method of manufacturing a non-molded solid fuel using a combustible waste material includes (a) primarily crushing an inflowing waste material using a bag-tearing and crushing device, (b) separating iron from the primarily crushed waste material using a first magnetic sorter, (c) sorting the waste material, from which the iron is separated, according to the particle size of the waste material using a first oscillating multi-stage particle-size sorter, (d) secondarily crushing the waste material having a large particle size using an impact crusher, (e) separating the iron from the secondarily crushed waste material using a second magnetic sorter, (f) sorting the waste material, from which the iron is separated, according to the weight of the waste material using a wind power sorter, (g) separating the iron from a light material, and (h) pulverizing the waste material, from which the iron is separated.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: August 14, 2018
    Assignees: JST CO., LTD., SAMHO ENVIRO-TECH INC.
    Inventors: Jang Kun Lee, Jong Hyeok Oh, Mun Ju Kim, Dong Hyun Song, Hyun Kyu Jung
  • Patent number: 10047313
    Abstract: This application relates to the polymorphism and microstructure of certain triacylglycerols and fatty acid methyl esters, including 1,2-dioleoyl-3-stearoyl glycerol and methyl stearate, and how the properties of these individual components in a biodiesel fuel, as well as their combined mixtures, helps understand the fundamental mechanisms of their crystallization so as to design biodiesel fuels with improved low temperature characteristics.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: August 14, 2018
    Assignee: Trent University
    Inventors: Suresh Narine, Laziz Bouzidi, Athira Mohanan
  • Patent number: 10047314
    Abstract: The use is described of polymers which contain, in copolymerized form, an ?-olefin, a vinyl ester and an ester of an ?,?-unsaturated carboxylic acid as an additive for fuel oils and lubricants and in particular as a cold flow improver in fuel oils. In addition, the fuel oils and lubricants additized with these polymers; and also additive packages comprising such polymers are described.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: August 14, 2018
    Assignee: BASF SE
    Inventors: Wolfgang Ahlers, Andreas Fechtenkoetter, Frank-Olaf Maehling, Irene Troetsch-Schaller, Ansgar Eisenbeis
  • Patent number: 10047315
    Abstract: The present invention provides a refrigerating machine oil comprising: a base oil comprising an ester of a polyhydric alcohol and a fatty acid comprising 20 to 100% by mol of a branched fatty acid having 4 to 9 carbon atoms; and 0.2 to 0.5% by mass of a phenol-based antioxidant based on a total amount of the refrigerating machine oil, and the refrigerating machine oil being used with trifluoroethylene refrigerant.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: August 14, 2018
    Assignee: JXTG NIPPON OIL & ENERGY CORPORATION
    Inventors: Hitoshi Takahashi, Tsutomu Takahashi, Souichirou Konno
  • Patent number: 10047316
    Abstract: The disclosure provides a fluoropolyether compound represented by formula (1): R1—CH2—R2—CH2—R3 wherein R1 is C1-C10 alkoxy; R2 is —(CF2)pO(CF2O)x(CF2CF2O)y(CF2CF2CF2O)z(CF2CF2CF2CF2O)w(CF2)p—; x and y are each a real number of 0 to 30; z is a real number of 0 to 30; w is a real number of 0 to 20; p is an integer of 1 to 3; R3 is —OCH2CH(OH)CH2OH, —OCH2CH(OH)CH2OCH2CH(OH)CH2OH, —O(CH2)mOH, or —OCH2(OH)CHCH2—OC6H4—R4; m is an integer of 2 to 8; and R4 is hydrogen, C1-C4 alkoxy, amino, or an amide residue; and also provides a lubricant having the compound and a magnetic disk.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: August 14, 2018
    Assignee: Moresco Corporation
    Inventors: Ryosuke Sagata, Haruo Kasai
  • Patent number: 10047317
    Abstract: Disclosed is a fluoropolyether compound comprising a C4-10 aliphatic hydrocarbon chain present in the middle of the fluoropolyether compound and at least two perfluoropolyethers.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: August 14, 2018
    Assignee: Moresco Corporation
    Inventors: Ryosuke Sagata, Tsuyoshi Shimizu, Haruo Kasai
  • Patent number: 10047318
    Abstract: The present invention concerns the use as perfuming ingredient of a composition of matter comprising at least 94% w/w of 4,6-dimethyl-3-octen-5-ol, and at most 1% w/w of 2-methylpent-2-en-1-ol and 3-ethyl-4-methylhexan-2-one.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: August 14, 2018
    Assignee: Firmenich SA
    Inventors: Christian Vial, Lionel Saudan
  • Patent number: 10047319
    Abstract: The present invention concerns the use of 1-isopropoxy-1-oxopropan-2-yl pivalate, in the form of any one of its stereoisomers or a mixture thereof, as perfuming ingredient to impart odor notes of the floral and fruity type.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: August 14, 2018
    Assignee: Firmenich SA
    Inventor: Christian Vial
  • Patent number: 10047320
    Abstract: The present invention relates to a method for recovering crude tall oil from a soap which method comprises the steps of: determining a correlation between the crude tall oil content and the water content of the soap, determining an amount of acid and water needed in order to separate an optimal amount of crude tall oil from the soap dependent on the crude tall oil content of the soap, measuring the water content of the soap, adding the optimal amount of acid and water to the soap, mixing the added acid and water with the soap whereby an acidulated soap is formed and the crude tall oil is separated and recovering the separated crude tall oil from the acidulated soap.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: August 14, 2018
    Assignee: Stora Enso OYJ
    Inventors: Tiia Finer, Olli Timonen
  • Patent number: 10047321
    Abstract: A liquid surfactant composition can include a C9-C20 alkylbenzene sulfonate, a first alcohol ether sulfate (AES), and a nonionic surfactant. The first AES surfactant can have a molecular formula of R1—O—(CH2—CH2—O)m—SO3M, wherein R1 represents a C10-C20 alkyl group, m represents a number from 6 to 8, and M represents a monovalent cation. The first AES surfactant can be a modified oxo-alcohol-based surfactant.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: August 14, 2018
    Assignee: HENKEL AG & CO. KGAA
    Inventors: Frank Meier, Bin Lin, Natalie Mast, Pamela Lam, Jack John O. Hudson
  • Patent number: 10047322
    Abstract: Agent for removing spots or deposits from hard or soft surfaces. The agent includes surfactants, an adhesion promoter, and at least one active substance, wherein the adhesion promoter is selected from the group of the alkylene-styrene copolymers, the olefin homopolymers or olefin copolymers of two or more olefins, wherein the polymers can also be hydrogenated, and the polyalkylene derivatives, the active substance is an acid, an alkali, a bleaching agent, and/or hydrophobic organic solvent not bound in a gel, and the agent includes either at least 10 wt % of at least one acid or at least 10 wt % of at least one alkali and/or at least 5 wt % of a bleaching agent and/or includes at least 10 wt % of hydrophobic organic solvent not bound in a gel.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: August 14, 2018
    Assignee: BUCK SERVICE GMBH
    Inventors: Joachim Leipold, Edgar Jaeschke, Antje Schirmer
  • Patent number: 10047323
    Abstract: A phosphate-free automatic dishwashing detergent composition in unit-dose form having a weight of from about 8 to about 25 grams, the composition comprising: i) greater than about 5 to about 8 grams of an organic complexing agent; ii) a dispersant polymer; iii) from about 1 to about 3 grams of bleach and wherein the complexing agent and the dispersant polymer are in a weight ratio of from about 5:1 to about 25:1.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: August 14, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Nathalie Sophie Letzelter, Ashmita Randhawa, Sandrine Annette Henriette Viallet
  • Patent number: 10047324
    Abstract: The present invention provides a beneficial composition comprising (a) an encapsulated benefit agent composition comprising: a core comprising at least one benefit agent, and a water-insoluble shell; and (b) a suspension medium comprising: at least one suspending polymer, and at least one clay. The present invention also provides methods of using such a beneficial composition. In addition, the present invention provides methods of making a beneficial composition comprising: (a) providing an encapsulated benefit agent composition comprising a core comprising at least one benefit agent and a water-insoluble shell; (b) providing a suspension medium comprising at least one suspending polymer and at least one clay; (c) adding the encapsulated benefit agent composition to the suspension medium; and (d) mixing the suspension medium and the encapsulated benefit agent composition to form a substantially uniform aqueous suspension.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: August 14, 2018
    Assignee: Henkel IP & Holding GmbH
    Inventors: Madhusudan Patel, Kristen Higgins, Ryan Bradley Cameron, Janet Coope-Epstein, Maxime Pelletier, Cynthia L. Moser
  • Patent number: 10047325
    Abstract: Phosphorus-free detergent compositions are provided. Detergent compositions including an aminocarboxylate, water conditioning agent, source of alkalinity and water beneficially do not require the use of additional surfactants and/or polymers to provide suitable detergency and prevent scale build-up on treated surfaces. The detergent compositions are used with a sanitizer to employ the phosphorus-free detergent compositions for use as low temperature ware wash detergents that beneficially reduce scale build-up. Methods of employing the phosphorus-free detergent compositions are also provided.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: August 14, 2018
    Assignee: Ecolab USA Inc.
    Inventors: Erin Jane Dahlquist Howlett, Carter M. Silvernail, Steven E. Lentsch, Terrence P. Everson
  • Patent number: 10047326
    Abstract: An azeotropic-like composition containing 2-chloro-1,3,3,3-tetrafluoropropene and 1-chloro-3,3,3-trifluoropropene is provided. The azeotropic-like composition according to the present invention is non-flammable, has little influence on the environment, and has substantially the same composition ratio in the liquid phase and the gas phase. By use of an azeotropic-like composition according to the present invention, a washing detergent, a solvent, a silicone solvent, a foaming agent, a coolant, a heating medium for a heat pump, and a high temperature working fluid that are non-flammable, have little influence on the environment, and have substantially the same composition ratio in a liquid phase and a gas phase thereof may be provided.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: August 14, 2018
    Assignee: CENTRAL GLASS COMPANY, LIMITED
    Inventors: Masahiko Tani, Hideaki Imura, Yoshio Nishiguchi, Naoto Takada
  • Patent number: 10047327
    Abstract: Water-soluble unit dose article comprising a water-soluble film and a liquid laundry detergent composition, wherein the liquid laundry detergent composition comprises; a) an anionic surfactant; b) a non-ionic surfactant; c) 1,2-propanediol; d) dipropylene glycol.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: August 14, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Robby Renilde Francois Keuleers, Regine Labeque, Stefan Schittko
  • Patent number: 10047328
    Abstract: The present invention relates to unit dose detergent compositions comprising a water-soluble container formed from a water-soluble film material enclosing a liquid composition with a relatively high water content. In one embodiment, the unit dose detergent composition comprises a water-soluble container formed from a water-soluble film material enclosing a liquid composition, wherein the liquid composition comprises (a) at least one surfactant, (b) at least one humectant selected from the group consisting of polyols having 3 to 9 carbon atoms, and (c) about 15 wt % to about 35 wt % of water.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: August 14, 2018
    Assignee: Hekel IP & Holding GmbH
    Inventors: Syed Humza Naqvi, Troy Robert Graham, Ryan Bradley Cameron
  • Patent number: 10047329
    Abstract: A composition comprising an ethylene (mem)acrylic acid copolymer and a crosslinking agent is provided. The composition is able to form a film composition, which selectively disintegrates in media with high water content, depending on the ionic strength of the media.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 14, 2018
    Assignee: Rohm and Haas Chemicals LLC
    Inventors: Scott Backer, Afia S. Karikari, Paul Mercando
  • Patent number: 10047330
    Abstract: The present invention provides beverages and pharmaceutical compositions containing a deuterated alcohol according to Formula 1, and provides methods for their manufacture and use. The compositions of the invention are expected to ameliorate some of the negative side effects associated with the consumption of alcohol, such as hangover and facial flushing.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: August 14, 2018
    Assignee: Deuterla Beverages, LLC
    Inventors: Anthony W Czarnik, Jeffrey A McKinney
  • Patent number: 10047331
    Abstract: A tray (100; 400; 500; 600) for accommodating a cell culture (101), such as an embryo, for use during culturing thereof and for optical monitoring of the cell culture, e.g. during in vitro fertilization comprises a carrier structure (104;404;504;604) defining at least one accommodating zone (102; 402; 502; 602) for accommodating the cell culture. At least one focal lens (110; 410; 510; 610), notably a numerical aperture increasing lens is integrally formed with the carrier structure to facilitate monitoring of the cell culture through the carrier structure. A diameter of the focal lens may exceed a diameter of the at least one accommodating zone. The focal lens may be integrally molded with the carrier structure from a thermoplastic material.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 14, 2018
    Assignee: UNISENSE FERTILITECH A/S
    Inventors: Jonas Lerche Hansen, Niels B. Ramsing, Søren Porsgaard, Holger Søe Plougsgaard, Mai Faurschou Isaksen
  • Patent number: 10047332
    Abstract: The invention relates to a bag locking mechanism comprising, a fixed locking means (106), provided with a first abutment surface (116), a movable locking means (108; 208), which is movable between a locking position and a releasing position, and a second abutment surface (118; 218) arranged on the movable locking means (108; 208). The fixed locking means (106) defines by its configuration, at least partly a restricted locking space (114), in which the movable locking means (108; 208) is movable between the locking and releasing position.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 14, 2018
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventor: Patrik Akerstrom
  • Patent number: 10047334
    Abstract: A biological sterilization indicator (BI). The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: August 14, 2018
    Assignee: 3M Innovative Properties Company
    Inventors: Sailaja Chandrapati, Heather M. Webb, Jeffrey C. Pederson, Jeffrey D. Smith, RuthAnn R. Duda, Brian J. Engel
  • Patent number: 10047335
    Abstract: A cell picking support device, a display device and a culture container that can enhance work efficiency. An adapter fixes a well plate that holds cells cultured in a cell culture observation device. A control unit reads culture observation information that includes cell information and coordinate information, from a memory card that is fitted to an external memory I/F. A display unit is provided on a placing surface side of the well plate that is fixed by the adapter, and in response to control by the control unit, displays the cell information, read from the memory card, at display positions corresponding to positions on the bottom face of the well plate, as specified by the coordinate information. Embodiments can be used, for instance, as a cell picking support device that supports a picking operation that is performed in a clean bench.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: August 14, 2018
    Assignee: NIKON CORPORATION
    Inventor: Yasujiro Kiyota
  • Patent number: 10047336
    Abstract: Provided is an eco-friendly heliostat odor removal system, including: a solar cell which collects sunlight to generate electricity; an effective microorganism activation and cultivation box which purifies inflow contaminated air using an effective microorganism cultivation solution accommodated in a housing; a sunlight tracker which rotates or moves the solar cell to track the sun in accordance with an altitude of the sun; a controller which controls the effective microorganism activation and cultivation box and the sunlight tracker; and a battery storing unit which stores the electricity generated in the solar cell. Therefore, the power is supplied in an eco-friendly manner using solar heat energy and contaminated air is efficiently removed from industrial sites or a region where other odor is continuously generated by the effective microorganism cultivation solution.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: August 14, 2018
    Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Cheol Woo Park
  • Patent number: 10047337
    Abstract: Some embodiments include a method of culturing one or more microalgae. The method can include: inoculating a bioreactor with the one or more microalgae and a fluidic support medium, the bioreactor having one or more bioreactor walls at least partially enclosing a bioreactor cavity, being configured to be at least one of folded up or rolled up, and being sterile when the bioreactor is inoculated with the one or more microalgae, the one or more bioreactor walls comprising at least one bioreactor wall material, and the at least one bioreactor wall material being flexible and at least partially transparent; and vitally supporting the one or more microalgae. Other embodiments of related systems and methods are also disclosed.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: August 14, 2018
    Assignee: Heliae Development LLC
    Inventors: Luke Cizek, Miquel Olaizola, Mason McCarty, Mason Oelschlager
  • Patent number: 10047338
    Abstract: An algae culture method capable of efficiently producing an osmotic pressure adjusting substance, a production method of the substance, and an algae culture method for recovering carbon dioxide from a mixed gas containing carbon dioxide and sulfurous acid gas. The methods involve preparing a plurality of enrichment cultures each containing betaine by culturing a culture of microalgae derived from an environmental specimen under a photoautotrophic condition and under a plurality of culture conditions; making a cultivation plan in which an optimum enrichment culture suitable for a main culture is selected from the plurality of enrichment cultures; producing a main culture that contains betaine under the photoautotrophic condition and a salt concentration of 10 wt. % or more; and separating betaine. In the main culture, the algae containing betaine are cultured while the mixed gas containing sulfurous acid gas and carbon dioxide is blown to a culture solution of the algae.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: August 14, 2018
    Assignees: EUGLENA CO., LTD., SHIMIZU CORPORATION
    Inventors: Kengo Suzuki, Ryohei Nakano, Hideyuki Adachi, Ayaka Nakashima, Eriko Yoshida, Masaharu Tasaki, Yoichi Kuroiwa, Keisuke Kojima, Takeshi Hasegawa
  • Patent number: 10047339
    Abstract: The present invention generally relates to compositions and methods of delivering living cells in a dry mode, wherein the compositions include a surface layer disposed on the outer surface of the composition that is permeable to carbon dioxide and oxygen. The compositions may be used to deliver living cells to a delivery point without the use of expensive refrigerants such as dry ice or liquid nitrogen.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: August 14, 2018
    Assignee: DRYLET, LLC
    Inventors: Ramiro Trevino, Steven R. Ellis
  • Patent number: 10047340
    Abstract: Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous MHC allele cell lines are provided. These cells are produced preferably from parthenogenic, IVF, or same-species or cross-species nuclear transfer embryos or by dedifferentiation of somatic cells by cytoplasm transfer. Methods for using these stem cell banks for producing stem and differentiated cells for therapy, especially acute therapies, and for screening for drugs for disease treatment are also provided.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: August 14, 2018
    Assignee: Advanced Cell Technology, Inc.
    Inventor: Michael West
  • Patent number: 10047341
    Abstract: Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: August 14, 2018
    Assignee: FUJIFILM Cellular Dynamics, Inc.
    Inventors: Junying Yu, Ying Zhang, Lisa Harms
  • Patent number: 10047342
    Abstract: The invention relates to an elutriation chamber for an elutriator system for washing and/or isolating cells, in particular thrombocytes, which elutriation chamber comprises a feed line (1) for an aqueous medium containing the cells to be washed and/or to be isolated in suspended form, and a discharge line (2) for the washed and/or isolated cells, wherein the chamber (5) is rotationally symmetrical to the axis (a), characterized in that the ratio of the area of the section through the lumen of the chamber (5) perpendicular to the axis (a) at the widest point (5a-5b) to the area of the section (1a) through the feed line (1) is in the range of 1,000 to 250,000.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: August 14, 2018
    Assignee: BIO-PRODUCTS & BIO-ENGINEERING AG
    Inventors: Johann Eibl, Johann Graus, Christoph Mader
  • Patent number: 10047343
    Abstract: The present disclosure provides methods of producing cartilage in vitro. The present disclosure provides treatment methods, involving introducing in vitro-produced cartilage into a treatment site in vivo. The present disclosure provides methods of enhancing bone formation, the method involving introducing in vitro-produced hypertrophic cartilage into a treatment site in vivo.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: August 14, 2018
    Inventor: Alfred Kuo
  • Patent number: 10047344
    Abstract: The invention provides, inter alia, populations of large mesenchymal stem cells (MSC)(as well as conditioned medium from these cells) with enhanced regenerative potential, as well as methods of culturing and using these populations, such as therapeutic methods of mediating tissue repair or enhancing homing and engraftment of hematopoietic stem cells. These large MSC populations can, in certain embodiments, be produced by biophysically sorting an MSC-containing population.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: August 14, 2018
    Assignees: National University of Singapore, Massachusetts Institute of Technology
    Inventors: Zhiyong Poon, Wong Cheng Lee, Krystyn J. Van Vliet
  • Patent number: 10047345
    Abstract: Methods of culturing mesenchymal stem cells are provided. The methods comprise culturing MSCs in a medium comprising nicotinamide and fibroblast growth factor 4 (FGF4). Populations of mesenchymal stem cells generated using the methods described herein and uses thereof are also provided.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: August 14, 2018
    Assignee: Gamida-Cell Ltd.
    Inventors: Tony Peled, Yair Steinhardt
  • Patent number: 10047346
    Abstract: This document provides methods and materials related to induced pluripotent stem cells. For example, induced pluripotent stem cells, compositions containing induced pluripotent stem cells, methods for obtaining induced pluripotent stem cells, and methods for using induced pluripotent stem cells are provided. In addition, methods and materials for using induced pluripotent stem cells to repair tissue (e.g., cardiovascular tissue) in vivo as well as methods and materials for using induced pluripotent stem cells to assess their therapeutic potential in appropriate animal models are provided.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: August 14, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Yasuhiro Ikeda, Andre Terzic, Timothy J. Nelson, Amber A. Mael, Almudena J. Martinez Fernandez, Satsuki Yamada
  • Patent number: 10047347
    Abstract: The invention relates to a recombinant adenovirus that has an oncolytic effect in a cancer cell. By modulating the level and type of splice isoforms of the E1B gene product, expressed from the E1B gene, the oncolytic activity of such viruses can be enhanced. The invention provides a recombinant adenovirus in which the proportion of the E1B-156R isoform is increased relative to wild-type levels. Such a recombinant adenovirus may selectivity replicate in cancer cells, thereby killing cancer cells while sparing normal cells.
    Type: Grant
    Filed: November 29, 2013
    Date of Patent: August 14, 2018
    Assignee: Ixogen Ltd.
    Inventor: Hans Daniel Öberg
  • Patent number: 10047348
    Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: August 14, 2018
    Assignee: Codexis, Inc.
    Inventors: Emily Mundorff, Erik Jan De Vries
  • Patent number: 10047349
    Abstract: A DNA polymerase, having an amino acid sequence represented by SEQ ID No. 2, or a derivative of the amino acid sequence by substitution, deletion, or addition of at least one amino acid residue. The DNA polymerase is a hybrid DNA polymerase prepared by inserting a thioredoxin binding domain (TBD) of bacteriophage T7 DNA polymerase into a DNA polymerase I (Sau) of Staphylococcus aureus. A method for preparing the DNA polymerase includes: 1) determining a corresponding position and a target substitution sequence in Sau protein for the TBD of the bacteriophage T7 DNA polymerase; 2) devising and synthesizing a primer according to a gene sequence of Sau and a sequence TBD published by GenBank; 3) cloning the Sau-TBD segment acquired in (2) to an expression vector pTrc99A to construct a recombinant vector pTrc99A-Sau-TBD; and 4) transforming Escherichia coli by the recombinant vector pTrc99A-Sau-TBD and inducing protein expression.
    Type: Grant
    Filed: September 5, 2016
    Date of Patent: August 14, 2018
    Assignee: HANGZHOU ZHONGCE BIO-SCI&TECH. CO., LTD.
    Inventors: Qi Cheng, Bing Zhai, Joseph Chow, Xianzhen Li, Guoxian Liu
  • Patent number: 10047350
    Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: August 14, 2018
    Assignee: BASF Enzymes LLC
    Inventors: Walter Callen, Toby Richardson, Gerhard Frey, Jay M. Short, Eric J. Mathur, Kevin A. Gray, Janne S. Kerovuo, Malgorzata Slupska