Patents Issued in August 21, 2018
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Patent number: 10053625Abstract: A display device includes a first substrate, a second substrate, and a liquid crystal layer. The second substrate faces the first substrate. The liquid crystal layer is disposed between the first substrate and the second substrate. The liquid crystal layer includes liquid crystal molecules having negative dielectric constant anisotropy and an additive. The additive may be 2,6-di-tert-butyl phenol in which at least one position of a 3-position, 4-position and 5-position is substituted with a substituent.Type: GrantFiled: November 4, 2015Date of Patent: August 21, 2018Assignee: SAMSUNG DISPLAY CO., LTD.Inventor: Hyelim Jang
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Patent number: 10053626Abstract: The present provides a method of fabricating a polymer dispersed liquid crystal (PDLC) thin film. The method of fabricating the PDLC of the present application forms the first solution by mixing the liquid crystal and the graphene nanoparticles; prepares the prepolymer by using the citric acid and the 1,8-octanediol, or the citric acid, the 1,8-octanediol and the 1,8-octanediol; forms the second solution by dissolving the prepolymer in the anhydrous ethanol; then obtains the mixture prepolymer of the polymer dispersed liquid crystal and the graphene nanoparticles by mixing and uniformly stirring the first solution and the second solution; and obtains the PDLC thin film after the mixture prepolymer is polymerized for several days.Type: GrantFiled: December 24, 2015Date of Patent: August 21, 2018Assignee: SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Chao Ma, Yungjui Lee
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Patent number: 10053627Abstract: A method of testing the coking qualities of sample quantities of coal in a test container and the structure of the test container are disclosed. A test container which is ideally reusable is adapted to receive one or more samples of coal to be tested and then the test container is inserted into a coking oven along with additional, conventional coal during a conventional coking operation. Following the completion or substantial completion of the coking operation, the test container is recovered and from the conventional converted coke and the sample(s) of coke are removed from the container for testing and evaluation. The container is recharged with one or more additional samples of coke and reused in another conventional coking operation.Type: GrantFiled: September 25, 2015Date of Patent: August 21, 2018Assignee: SUNCOKE TECHNOLOGY AND DEVELOPMENT LLCInventors: Jacob P. Sarpen, John F. Quanci, Mark A. Ball, Paul J. Norton, Roy J. Griffey, Jose Eustaquio daSilva
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Patent number: 10053628Abstract: The present invention relates to a method for treating carbonaceous materials by steam thermolysis, comprising: shredding carbonaceous waste materials; introducing the shredded carbonaceous waste materials into a reactor heated by combustion gases, gases laden with steam being introduced into the reactor so as to heat said shredded carbonaceous waste materials to a temperature between 200 and 700° C. during a steam thermolysis reaction; cooling the combustion gases to a temperature between 200 and 450° C. and discharging said gases; discharging from the reactor the vapor/gas products formed in the reactor by steam thermolysis, followed by condensation of said products; separating the condensate obtained from said condensation into water containing residual hydrocarbons and into oil, and the water from the condensate being used as a source of heat energy for the reactor. The present invention also relates to a device for implementing the invention.Type: GrantFiled: March 8, 2013Date of Patent: August 21, 2018Assignee: ALPHA RECYCLAGE FRANCHE COMTEInventor: Jean-Louis Pech
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Patent number: 10053629Abstract: Ultra-clean char is used to generate hydrocarbons and/or electricity in a clean environmentally friendly process. The ultra-clean char is produced by pyrolizing organic matter, such as coal or various organic waste. The pyrolized organic matter may be combusted in the presence of oxygen to produce heat, which can be used to generate electricity in a conventional boiler/generator system. Further, pyrolized organic matter can be combusted in the presence of carbon dioxide and further processed to produce various hydrocarbons. In other embodiments, the ultra-clean char may be subjected to an extraction process for capturing valuable rare earth elements.Type: GrantFiled: August 28, 2017Date of Patent: August 21, 2018Assignee: Saga Fuel Systems, Inc.Inventor: Deborah Wenzel
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Patent number: 10053630Abstract: A delayed coking process in which shot coke and thermally cracked coker products are produced from a sponge coke- and/or transition coke-forming resid feed comprising sponge coke asphaltenes by mixing heteroatom (preferably nitrogen) containing asphaltenes from a shot coke-forming resid with a heated sponge coke-forming resid to form shot coke directing asphaltene aggregates in the resid. The mixture of resid with the added asphaltene is held at an elevated temperature to allow co-aggregates of sponge coke and shot coke asphaltenes to form which, upon delayed coking promote the production of a free-flowing shot coke product.Type: GrantFiled: April 28, 2015Date of Patent: August 21, 2018Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Michael Siskin, Ramesh Varadaraj
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Patent number: 10053631Abstract: Provided are a method of preparing a high softening point pitch and the high softening point pitch prepared thereby, in which a polyene radical intermediate is formed, and an alkylaromatic radial material is linearly linked to the polyene radical intermediate in a benzyl or methylene form to be polymerized. The method includes performing heat treatment by adding a compound, which is able to a polyene radical intermediate, to 1- to 4-ring alkylaromatic condensates to produce a basic pitch, and performing vacuum heat treatment for the basic pitch.Type: GrantFiled: April 22, 2016Date of Patent: August 21, 2018Assignee: YUSUNG TELECOM CO., LTD.Inventors: Sung Ho Yoon, Seong Hwa Hong, Suk Jun Yu
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Patent number: 10053632Abstract: A process for extracting bitumen from oil sand ore to produce a bitumen froth having reduced solids is provided, comprising mixing the oil sand ore with water and a first process aid comprising at least one surfactant to form an oil sand slurry; conditioning the oil sand slurry to produce a conditioned oil sand slurry; and introducing the conditioned oil sand slurry into a separation zone for forming the bitumen froth having reduced solids.Type: GrantFiled: July 20, 2016Date of Patent: August 21, 2018Assignee: SYNCRUDE CANADA, LTD.Inventor: Jun Long
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Patent number: 10053633Abstract: This disclosure relates to the production of xylenes from syngas, in which the syngas is converted to an aromatic product by reaction with a Fischer-Tropsch catalyst and an aromatization catalyst. The Fischer-Tropsch catalyst and aromatization catalyst may be different catalysts or combined into a single catalyst. The aromatic product is then subjected to selective alkylation with methanol and/or carbon monoxide and hydrogen to increase its p-xylene content.Type: GrantFiled: October 2, 2017Date of Patent: August 21, 2018Assignee: ExxonMobil Chemical Patents Inc.Inventors: James H. Beech, Jr., Nikolaos Soultanidis, Steven E. Silverberg
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Patent number: 10053634Abstract: An input stream of gaseous nitrogen and carbon dioxide is introduced into a first interior volume of a separation vessel that is divided into first and second interior volumes by a separation membrane that includes a metal layer. The metal layer selectively permits movement of nitrogen through the metal layer. An output stream of gaseous nitrogen and carbon dioxide is conveyed out of the first interior volume and into a reaction vessel. The volume fraction of carbon dioxide is greater in the output stream than in the input stream; the volume fraction of nitrogen is reduced in the output stream relative to the input stream. Nitrogen is removed from the second interior volume to maintain a gradient of nitrogen partial pressure across the separation membrane that causes net transport of nitrogen from the first interior volume through the separation membrane into the second interior volume.Type: GrantFiled: June 30, 2017Date of Patent: August 21, 2018Assignee: ECOKAP TECHNOLOGIES LLCInventors: Paul E. King, Jennifer Wilcox
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Patent number: 10053635Abstract: A method is disclosed for the treatment of a liquid, in particular a mineral oil, for increasing the portion of low-boiling fractions. The treatment comprises generating pressure waves having a first frequency, subjecting the liquid to said pressure waves in a region of application and feeding the so-treated liquid to a tank. At least one pipe flowed through by the treated liquid and immediately following said region of application is excited to oscillations of a second frequency, which is the resonance frequency of the excited system.Type: GrantFiled: April 14, 2011Date of Patent: August 21, 2018Assignee: PRISTEC AGInventors: Jose Miguel Delgado Castillo, Anibal Luis Veneciano Rivera, Ruediger Uwe Nuerk, Fedor Chernikov
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Patent number: 10053636Abstract: Systems and methods for separation of hydrocarbon containing fluids are provided. More particularly, the disclosure is relevant to separating fluids having a gas phase, a hydrocarbon liquid phase, and an aqueous liquid phase using indirect heating. In general, the system uses a first three-phase gas separation followed by indirect heating and then a second three-phase gas separation. Pressure reduction of the hydrocarbon containing fluid occurs either before or after the indirect heating.Type: GrantFiled: August 24, 2017Date of Patent: August 21, 2018Assignee: John Zink Company, LLCInventors: Stephen Joseph Rehm, Timothy Warren Oneal, Gene Wesley Bittel, Mark Elliot Ferguson, Daniel Todd Wright, Nicholas Lee Jensen, Todd Ethan Earls
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Patent number: 10053637Abstract: A hydroprocessing catalyst has been developed. The catalyst is a unique transition metal tungsten oxy-hydroxide material. The hydroprocessing using the transition metal tungsten oxy-hydroxide material may include hydrodenitrification, hydrodesulfurization, hydrodemetallation, hydrodesilication, hydrodearomatization, hydroisomerization, hydrotreating, hydrofining, and hydrocracking.Type: GrantFiled: December 13, 2016Date of Patent: August 21, 2018Assignee: UOP LLCInventors: Stuart Miller, Susan C. Koster
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Patent number: 10053638Abstract: Methods are provided for dewaxing a distillate fuel boiling range feed to improve one or more cold flow properties of the distillate fuel feed, such as cloud point, with reduced consumption of hydrogen during the dewaxing process. The reduced hydrogen consumption is achieved by using a dewaxing catalyst with a reduced content of hydrogenation metals, such as a content of Pt or Pd of from about 0.03 wt % to about 0.35 wt %. A distillate fuel feed can be dewaxed to achieve a desired cloud point differential using a reduced metals content dewaxing catalyst under the same or similar conditions to those required for a dewaxing catalyst with higher metals content.Type: GrantFiled: February 28, 2014Date of Patent: August 21, 2018Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Xiaochun Xu, William J. Novak, Timothy L. Hilbert, Stephen J. McCarthy
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Patent number: 10053639Abstract: Methods are provided for dewaxing a distillate fuel boiling range feed to improve one or more cold flow properties of the distillate fuel feed, such as cloud point, where the distillate fuel feed is fractionated to produce both a jet fuel product and an arctic diesel fuel product. The decrease of cloud point is achieved by using a feedstock having a concentration of nitrogen of less than about 50 wppm and a concentration of sulfur of less than about 15 wppm. Further, the dewaxing catalyst may have a reduced content of hydrogenation metals, such as a content of Pt or Pd of from about 0.05 wt % to about 0.35 wt %. A distillate fuel feed can be dewaxed to achieve a desired cloud point differential using a reduced metals content dewaxing catalyst under the same or similar conditions to those required for a dewaxing catalyst with higher metals content.Type: GrantFiled: October 6, 2014Date of Patent: August 21, 2018Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Stuart S. Shih, Xiaochun Xu, William J. Novak, Carlos N. Lopez, Timothy Lee Hilbert, Stephen John McCarthy
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Patent number: 10053640Abstract: A method and kit for treatment of a stainless steel or other nickel alloy component utilized in a crude oil service operation including cleaning a surface of the component to remove surface contamination; drying the cleaned surface of the component; applying a coat of Self-Assembled Monolayer of Phosphonate (SAMP) to the cleaned and dried surface of the component to form a treated component; and installing the treated component into a section of a crude oil service operation. The coating reduces paraffin/asphaltene deposition on the component. The kit includes a cleaner wipe impregnated with a cleaning substance for cleaning the component; a nano-coating wipe impregnated with a SAMP for applying a nano-coating of the SAMP to the component; and instructions for treating said component utilizing the cleaner wipe and the nano-coating wipe.Type: GrantFiled: July 15, 2016Date of Patent: August 21, 2018Assignees: ACULON INC., ELECTROLAB, INCInventors: Eric Hanson, Edward Hughes, Sean Eric Drees, Andrew Timothy Marzec, Brian Keith Brashear
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Patent number: 10053641Abstract: A viscosity reducer based on vegetable extracts of natural origin is disclosed. The vegetable extracts include a mixture of phosphoglycerides and vegetable oils. A method of reducing the viscosity in heavy and extra heavy crude oil using the viscosity reducer is also disclosed. No aromatic base solvents are needed. A reduction in diluent usage is achieved using the viscosity reducer based on vegetable extracts. The viscosity reducer composition includes a mixture of phosphoglycerides, vegetable oil, non-aromatic solvent, polycyclic aromatic hydrocarbon and stabilizer.Type: GrantFiled: August 24, 2016Date of Patent: August 21, 2018Assignee: OIL & GAS TECH ENTERPRISES C.V.Inventor: Cridal Del Valle Sencial Bello
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Patent number: 10053642Abstract: There is described a method for producing a biofuel, the method comprising: culturing an Acetobacter lovaniensis bacterium in a growth medium containing phosphate at a level which is more than 1 g/liter, wherein culturing of the bacterium produces the biofuel.Type: GrantFiled: February 6, 2015Date of Patent: August 21, 2018Assignee: VERDANT BIOPRODUCTS LIMITEDInventor: Irene Finnegan
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Patent number: 10053643Abstract: A process for making high density fuels having the potential to increase the range and/or loiter time of Navy platforms. Derivation of these fuels from a sustainable source will decrease the carbon footprint of the Department of Defense (DoD) and reduce reliance on nonsustainable petroleum sources. Fuels derived from bisabolene can have volumetric net heats of combustion comparable to JP-10 and can be produced from biomass sugars.Type: GrantFiled: October 21, 2015Date of Patent: August 21, 2018Assignee: The United States of America as Represented by the Secretary of the NavyInventor: Benjamin G Harvey
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Patent number: 10053644Abstract: The present invention provides a refrigerating machine oil comprising a polyvinylether having a structural unit represented by the following formula (1): wherein R1, R2, and R3 may be the same or different from each other and each represent a hydrogen atom or a hydrocarbon group, R4 represents a divalent hydrocarbon group or an ethereal oxygen-containing divalent hydrocarbon group, R5 represents a hydrocarbon group, m represents an integer of 0 or more, and in the case where m is 2 or more, a plurality of R4 may be the same or different from each other, a number average molecular weight Mn is 500 or more and 2000 or less, a ratio of a weight average molecular weight Mw to a number average molecular weight Mn, Mw/Mn, is 1.10 or more and 1.25 or less, and the refrigerating machine oil is used with a mildly flammable hydrofluorocarbon refrigerant.Type: GrantFiled: February 2, 2015Date of Patent: August 21, 2018Assignee: JXTG Nippon Oil & Energy CorporationInventors: Hitoshi Takahashi, Tsutomu Takahashi, Takeshi Okido, Hiroko Shimpo, Souichirou Konno
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Patent number: 10053645Abstract: There is provided a resin composition for a machinable liner of a sliding member. An ultraviolet curable resin composition for a self-lubricating liner contains a (meth)acrylate compound having an isocyanuric acid ring represented by the following formula and PTFE as a solid lubricant. In the formula (1), X is a group which contains an acryloyl group and is composed only of C, H, and O. Y and Z are groups each composed only of C, H, and O. PTFE is contained in an amount of 10 to 50% by weight with respect to a total amount of the ultraviolet curable resin composition. The ultraviolet curable resin composition is suitable for a self-lubricating liner 24 of a spherical bearing 20 having an outer race 22 and an inner race 26.Type: GrantFiled: September 28, 2016Date of Patent: August 21, 2018Assignee: MINEBEA CO., LTD.Inventors: Tadahiko Karaki, Kunihiro Matsumoto, Koichiro Sagiyama
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Patent number: 10053646Abstract: Provided are microalgal compositions and methods for their use. The microalgal compositions include lubricants that find use in industrial and other applications.Type: GrantFiled: March 24, 2016Date of Patent: August 21, 2018Assignee: Corbion Biotech, Inc.Inventors: Celine Schiff-Deb, Adrienne McKee, John Piechocki, Staci Springer, Garrett Sell, Bryce A. R. Sullivan
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Patent number: 10053647Abstract: The present invention provides a working fluid composition for a refrigerating machine, comprising a refrigerating machine oil that comprises an ester of a polyhydric alcohol and a fatty acid, an epoxy compound, and a phosphorus compound, and a fluoropropene refrigerant, wherein the polyhydric alcohol constituting the ester comprises pentaerythritol and dipentaerythritol, the fatty acid constituting the ester comprises at least one selected from fatty acids having 4 to 9 carbon atoms, and the epoxy compound and the phosphorus compound satisfy a condition represented by the following formula (1). [ Formula ? ? 1 ] ? 0.10 ? ( N E M E · W E ) ( N P M P · W P ) ? 1.Type: GrantFiled: December 22, 2014Date of Patent: August 21, 2018Assignees: Denso Corporation, Kabushki Kaisha Toyota Jidoshokki, JX Nippon Oil & Energy CorporationInventors: Masataka Muto, Hajime Mukawa, Takekazu Kano, Genki Hayashi, Kazuki Yamamoto, Takahiro Hoshida, Hitoshi Takahashi, Ken Sawada, Akira Tada, Souichirou Konno
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Patent number: 10053648Abstract: A continuous-flow extraction system and method for extracting oil from oil-bearing plant parts, or biomass, with liquid-phase hydrocarbon solvent in a continuous process, providing more than one extraction vessel so that one or more extraction vessels can be cleared of exhausted biomass and reloaded with biomass, while another one or more extraction vessels are undergoing the extraction process, optionally providing a de-waxer for use when needed, providing a primary jacketed separator vessel for flashing hydrocarbon solvent to a vapor phase and precipitating and collecting liquid plant extract, providing at least one secondary jacketed separator vessel for purification and refinement of vapor-phase hydrocarbon solvent and providing for re-liquefication of the solvent for the purpose of re-circulating and reusing the solvent, and providing for the heating, cooling, and pumping necessary to carry out the various steps.Type: GrantFiled: May 10, 2017Date of Patent: August 21, 2018Inventor: Matthew Ellis
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Patent number: 10053649Abstract: The present invention relates to a method for removing turbidity-inducing agents from a lipid phase.Type: GrantFiled: June 1, 2015Date of Patent: August 21, 2018Assignees: Drei Lilien PVG GmbH & Co. KG, SE Tylose GmbH & Co. KGInventor: Max Dietz
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Patent number: 10053650Abstract: A fragrance composition is described which comprises at least two different fragrance accords, wherein at least 30 wt % of each fragrance accord comprises the key contributor(s) of said fragrance accord and wherein the average of the odor detection thresholds of said key contributor(s) for each fragrance accord is within the same order of magnitude as the average of the odor detection thresholds of the key contributor(s) for said other fragrance accord(s), and wherein the base note(s) of each fragrance accord comprises less than 15% of the notes of said accord. Methods of manufacture thereof, together with methods of attenuating fragrance habituation, are also described.Type: GrantFiled: January 9, 2017Date of Patent: August 21, 2018Assignee: RECKITT BENCKISER (BRANDS) LIMITEDInventors: Nathan Angel, Simon Hurry
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Patent number: 10053651Abstract: The present invention relates generally to methods of making surfactant compositions and detergent compositions.Type: GrantFiled: May 12, 2016Date of Patent: August 21, 2018Assignee: The Procter & Gamble CompanyInventors: Jeffrey John Scheibel, Scott Leroy Cron, Praveen Kumar Depa, Philip James Ganz, Daniele Lynn Hibbard, Dennis Allen Beckholt, Rajan Keshav Panandiker, Joia Kirin Spooner-Fleming, Diederik Emiel Omer Vanhoutte, Nicole Lee Arledge
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Patent number: 10053652Abstract: The present invention is a dimensionally stable solid detergent composition which can be used as a soaking composition. The composition includes a bio-based content of 58% or greater and includes an alkalinity source, a metal protector, a surfactant system, water, a threshold agent, and a polysaccharide hybrid polymer composition. The polymer the polysaccharide hybrid polymer composition includes a polysaccharide residue present in an amount from approximately 5% to 90% by weight of the polysaccharide hybrid polymer composition and a residue of at least one ethylenically unsaturated monomer or salts thereof present in an amount from approximately 10% to 75% by weight of the polysaccharide hybrid polymer composition.Type: GrantFiled: May 9, 2016Date of Patent: August 21, 2018Assignee: ECOLAB USA INC.Inventors: Amanda Ruth Blattner, Charles Allen Hodge, Carter M. Silvernail
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Patent number: 10053653Abstract: Ambient moisture-activatable surface treatment powders containing persalt, positively charged phase transfer agent and alkaline pH buffering may be activatable without the addition of liquid. Some ambient moisture-activatable surface treatment powders are substantially free of bleach activators and/or chlorine. Methods of use of ambient moisture activatable powders include applying them to the surfaces to be treated.Type: GrantFiled: October 18, 2017Date of Patent: August 21, 2018Assignee: Sterilex, LLCInventors: Edward Fu, Mark Wozniak, Chris Bergstrom
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Patent number: 10053654Abstract: A solid free-flowing particulate laundry detergent composition including: (a) from 0.1 wt % to 5 wt % hueing agent particle comprising: (i) from 2 wt % to 10 wt % hueing agent; and (ii) from 60 wt % to 98 wt % clay; and (b) from 0.5 wt % to 20 wt % ethoxylated alkyl sulphate particle including: (i) from 40 wt % to 60 wt % partially ethoxylated alkyl sulphate anionic detersive surfactant; (ii) from 20 wt % to 50 wt % salt; and (iii) from 10 wt % to 30 wt % silica.Type: GrantFiled: April 1, 2016Date of Patent: August 21, 2018Assignee: The Procter & Gamble CompanyInventors: Andre Chieffi, Jill Robyn Dorgan, Anthony McMeekin, Alan Thomas Brooker, Carly Pickering, Paul Anthony Gould, William Alexander Caufield, Laura Judith Smalley, Michael Richard Irvine
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Patent number: 10053655Abstract: The invention present describes novel cleaning agents based on a multiphase system, the use thereof for removing photoresist coatings from surfaces, and a method for removing photoresist coatings from surfaces. The multiphase system according to the invention is used in particular for removing coatings, photoresist coatings, polymer layers, dirt layers, insulation layers, and metal layers from surfaces.Type: GrantFiled: October 13, 2014Date of Patent: August 21, 2018Assignee: INTELLIGENT FLUIDS GMBHInventor: Dirk Schumann
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Patent number: 10053656Abstract: The invention discloses a multiphase detergent tablet (1), comprising a first detergent phase with at least one contact-unsuitable, in particular caustic, irritant, toxic or hygroscopic component and a second detergent phase to cover the first detergent phase, wherein the second detergent phase essentially contains no contact-unsuitable components, in particular no caustic, toxic or hygroscopic components, optionally also no irritant components and whereby the detergent tablet comprises at least three stacked layers, with a first layer (10) of the second detergent phase; a second middle layer (12) of the first detergent phase and a third layer (14) of the second detergent phase, wherein at least a part of a region of the contact-unsuitable first detergent phase that is not covered by a layer of the second detergent phase is provided with a water-soluble protective film.Type: GrantFiled: July 31, 2014Date of Patent: August 21, 2018Assignee: BUDICH INTERNATIONAL GMBHInventor: Meinrad Budich
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Patent number: 10053658Abstract: A process and apparatus for producing a solid, edible ethanol containing product which may be either a rubbery solid or a hard solid that is frozen about 24.8° F. (?4° C.). The product contains agar and gelatin and the ethanol may be provided in the form of selected alcoholic beverages.Type: GrantFiled: January 7, 2010Date of Patent: August 21, 2018Assignee: AEGSV VENTURES, LLCInventors: Gal Motzaeli, Shai Leibovich
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Patent number: 10053659Abstract: Embodiments of a modular tubular bioreactor system for culturing an aqueous culture of microorganisms are described herein. The tubular bioreactor may comprise culture tubes configured in a vertically spaced and horizontally staggered arrangement to optimize the application of light to the culture in phototrophic and mixotrophic cultivation.Type: GrantFiled: July 29, 2015Date of Patent: August 21, 2018Assignee: Heliae Development LLCInventors: Cameron Wyatt, Richard Mazur, James Riley, Thomas Kulaga, Alexander Sitek, Jason Licamele, Timothy Sullivan
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Patent number: 10053660Abstract: A polymer or other substrate optimized for growing cells is described, which takes the form of a micro-thin bag with gas permeable sides. Sides of the bag can be held at a fixed distance from one another with a multitude of tiny micropillars or other spacers extending between them, keeping the bag at a predetermined thickness and preventing the bag from collapsing and the sides from sticking together. In other embodiments, the sides may be held apart by gas pressure alone. A 0.01 ?m to 1000 ?m parylene or other biocompatible coating over the bag outsides controls the permeability of the bag material and provides a bio-safe area for cell growth. An alternate configuration uses open-cell foam with skins coated with a biocompatible coating. Tubes going into multiple bags can be connected to a manifold that delivers gaseous oxygen or removes carbon dioxide and other waste gases.Type: GrantFiled: July 11, 2017Date of Patent: August 21, 2018Assignees: California Institute of Technology, City of HopeInventors: Yu-Chong Tai, Yang Liu, Colin A. Cook, Yuman Fong, Nanhai G. Chen
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Patent number: 10053661Abstract: The present invention discloses a vessel for culturing cells which includes: a bottom, a top, a tubular neck, and, one or more shelves. The first shelf adjoins the top with the first shelf being located intermediate the bottom and the top. The bottom, the top and the one or more shelves collectively define an enclosed volume for culturing cells with the enclosed volume being accessible by the opening in the tubular neck. Advantageously, this vessel provides high volume cell culture in a manner that increases efficiency and reduces the cost of culturing cells.Type: GrantFiled: June 26, 2014Date of Patent: August 21, 2018Assignee: Corning IncorporatedInventors: William J. Lacey, Michael S. Shanler, Amy W. Cai
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Patent number: 10053662Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, which can then be fermented to produce ethanol. Biomass feedstock is dispersed in a liquid medium and then saccharified.Type: GrantFiled: August 15, 2016Date of Patent: August 21, 2018Assignee: XYLECO, INC.Inventors: Marshall Medoff, Thomas Craig Masterman
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Patent number: 10053663Abstract: The invention is directed to a centrifuge chamber comprising a cylinder having a base plate and a cover plate, a rotational axis with at least one port for input and/or output of liquids, at least one port for input of gases and at least one layer for cell culturing, wherein the layer for cell culturing comprises a gas-permeable membrane on which cells can be cultured and wherein the at least one port for input and/or output of gases is connected to the gas-permeable membrane.Type: GrantFiled: May 23, 2016Date of Patent: August 21, 2018Assignee: Miltenyi Biotec, GmbHInventors: Eiad Kabaha, Stefan Miltenyi, Ralf-Peter Peters
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Patent number: 10053664Abstract: The field of the invention relates to a device for incubating a sample. The present disclosure provides an incubator for shaking and/or heating at least one sample. The device comprises at least one inductor placed below an induction heating plate. A heat conducting plate is mounted onto the induction heating plate. The device further comprises a moving arrangement for placing the sample onto the heat conducting plate.Type: GrantFiled: May 30, 2013Date of Patent: August 21, 2018Assignee: STRATEC Biomedical AGInventors: Ruediger Retzlaff, Alexander Falkner
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Patent number: 10053665Abstract: A cell magnetic sorting system comprises a continuous magnetic cell sorting apparatus. The continuous magnetic cell sorting apparatus comprises a rotating magnetic field generator, a forward solenoid and a reverse solenoid; the forward solenoid and the reverse solenoid surround the rotating magnetic field generator in forward and reverse directions, one end of the forward solenoid is connected to a cell solution source, the other end of the forward solenoid is connected to one end of the reverse solenoid through a T-shaped tube, an inlet of a T-shaped tube is connected to an outlet of the forward solenoid, a first outlet of the T-shaped tube is connected to an inlet of the reverse solenoid, a second outlet of the T-shaped tube is connected to an inlet of the target cell collection container.Type: GrantFiled: July 19, 2016Date of Patent: August 21, 2018Assignee: SHENZHEN CYTOROLA BIOMEDICAL TECH CO., LTD.Inventors: Lifeng Zhang, Shubo Wan, Hua Wang
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Patent number: 10053666Abstract: Usage of a protein kinase inhibitor in preparing a neural cell from a differentiated non-neural cell is provided.Type: GrantFiled: September 29, 2014Date of Patent: August 21, 2018Assignee: SHENZHEN CELL INSPIRE BIOTECHNOLOGY CO., LTD.Inventors: Xiaohua Lu, Jiayin Yang, Bo Yang
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Patent number: 10053667Abstract: The present invention relates to the differentiation of human pluripotent cells, including human pluripotent stems cells to produce a self-renewing multipotent neural crest cell population in a single step method without the requirement of isolation of intermediate cells and without appreciable contamination (in certain preferred instances, virtually none) with Pax6+ neural progenitor cells in the population of p75+ Hnk1+ Ap2+ multipotent neural crest-like cells. The multipotent neural crest cell population obtained can be clonally amplified and maintained for >25 passages (>100 days) while retaining the capacity to differentiate into peripheral neurons, smooth muscle cells and mesenchymal precursor cells.Type: GrantFiled: January 19, 2016Date of Patent: August 21, 2018Assignee: University of Georgia Research Foundation, Inc.Inventors: Stephen Dalton, Laura M. Menendez
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Patent number: 10053668Abstract: The present invention relates to a factor for reprogramming bone endothelial cells to promote bone angiogenesis and osteogenesis as well as to an ex vivo method for reprogramming a bone endothelial cell to achieve cells able to mediate bone angiogenesis and osteogenesis. The subtype of bone endothelial cells mediating bone angiogenesis and osteogenesis express CD31 and Endomucin as markers.Type: GrantFiled: October 14, 2014Date of Patent: August 21, 2018Assignee: Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V.Inventors: Ralf H. Adams, Anjali Kusumbe, Saravana Ramasamy
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Patent number: 10053669Abstract: The present invention relates to a medium composition containing an Ecklonia cava extract for dedifferentiation an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced pluripotent stem cell produced by using the medium composition into osteoblasts. When using the medium composition according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into osteoblasts.Type: GrantFiled: November 5, 2013Date of Patent: August 21, 2018Assignee: BBHC Co., Ltd.Inventors: Sang Yeon Lee, Won Ju Jung, Ho Bin Kim, Min Sun Oh, Kye Ho Lee
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Patent number: 10053670Abstract: Isolated populations of mesenchymal stem cells (MSCs) are provided, including mammalian mesenchymal stem cells (MSCs) characterized by the lack of CD54 (CD54?) or low cell-surface CD54 (CD54low). Methods of in vitro cell differentiation and methods of treatment using said isolated populations are also provided.Type: GrantFiled: July 17, 2015Date of Patent: August 21, 2018Assignee: Escape Therapeutics, Inc.Inventor: Basil M. Hantash
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Patent number: 10053671Abstract: The disclosure provides for an isolated recombinant influenza virus having at least one of: a PA gene segment encoding PA with a residue at position 443 that is not arginine, a PB1 gene segment encoding PB1 with a residue at position 737 that is not lysine, a PB2 gene segment encoding PB2 with a residue at position 25 that is not valine or a residue at position 712 that is not glutamic acid, a NS gene segment encoding a NS1 with a residue at position 167 that is not proline, a HA gene segment encoding a HA with a residue at position 380 that is not threonine, or any combination thereof, and methods of making and using the virus.Type: GrantFiled: June 19, 2015Date of Patent: August 21, 2018Assignee: Wisconsin Alumni Research Foundation (WARF)Inventors: Yoshihiro Kawaoka, Satoshi Fukuyama, Shinji Watanabe
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Patent number: 10053672Abstract: The present invention relates to a method for obtaining an untransformed avian cell line enabling in vitro avian virus replication. Said method includes the following steps: a) culturing avian embryonic stem cells in the presence of a stroma for at least 3 days; b) culturing for at least 2 days in a medium having a low serum concentration; c) culturing for at least 2 days in a medium having a low serum concentration containing 1 to 10 mM of hexamethyleme bisacetamide (HMBA); d) culturing for at least 10 days in a medium having a low serum concentration; and e) culturing or freezing an avian cell line enabling avian virus replication. The invention also relates to the resulting cell line and to the use thereof in vaccine preparations.Type: GrantFiled: July 24, 2014Date of Patent: August 21, 2018Assignee: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUEInventors: Jean-François Vautherot, Bertrand Pain, Caroline Denesvre, Laetitia Fragnet-Trapp
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Patent number: 10053673Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.Type: GrantFiled: April 4, 2017Date of Patent: August 21, 2018Assignee: Codexis, Inc.Inventors: Michael A. Crowe, Oscar Alvizo, Behnaz Behrouzian, Yong Koy Bong, Steven J. Collier, Anupam Gohel, Jagadeesh Mavinahalli, Naga K. Modukuru, Emily Mundorff, Derek J. Smith, Shiwei Song, Wan Lin Yeo
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Patent number: 10053674Abstract: The present disclosure includes methods and compositions for reducing turf thatch and/or preventing turf thatch buildup. The compositions include isolated fungal laccase enzymes, such as laccase enzymes from white rot fungi. Methods of reducing and/or preventing turf thatch buildup include applying compositions including isolated fungal laccase enzymes to turfgrass.Type: GrantFiled: December 23, 2014Date of Patent: August 21, 2018Assignee: University of Georgia Research Foundation, Inc.Inventors: Qingguo Huang, Sudeep S. Sidhu, Paul L. Raymer, Robert N. Carrow
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Patent number: 10053675Abstract: Novel hydroxyphenyl pyruvate dioxygenase (HPPD) polypeptides, variants and fragments thereof, as well as polynucleotides encoding the same, capable of conferring commercial levels of conferring HPPD herbicide resistance or tolerance to plants. Compositions include amino acid sequences, and variants and fragments thereof, for HPPD polypeptides, as well as polynucleotides encoding the same. Methods for the production and use of HPPD herbicide resistant plants that express these novel HPPD polypeptides, methods for selectively controlling weeds in a field at a crop locus, and methods for the assay, characterization, identification and selection of these novel HPPDs are also provided.Type: GrantFiled: April 22, 2016Date of Patent: August 21, 2018Assignee: Syngenta Participations AGInventors: Timothy Robert Hawkes, Michael Phillip Langford, Russell Colin Viner, Richard Dale