Abstract: A complete cat feeding system includes a plurality of feeding devices, each of the feeding devices having a container for containing and dispensing a portion of cat's daily food ration. Each container has a convexly curved external surface, a first port and a second port arranged along a top portion of the container providing access to an interior space of the container, and a bridging wall separating the first port and the second port, the bridging wall extending above the first port and the second port. Each feeding device may further include a simulation covering constructed from a flexible material, the simulation covering having a pocket for receiving a portion of the container therein without covering the first port and the second port. The cat feeding system may include a training device providing a second container having more than two ports for containing and dispensing a portion of cat food.

Abstract: An interactive water container apparatus is disclosed and configured for encouraging an animal to drink therefrom. In at least one embodiment, an outer container is sized and configured for holding a volume of fluid, the outer container providing an at least one opening sized and configured for allowing the animal to access and drink the fluid therewithin. At least one inner container is positioned substantially within the outer container. At least one interactive object is positioned within the outer container such that the at least one inner container is positioned between the interactive object and the opening of the outer container, thereby allowing the animal to see said interactive object while being unable to physically contact said interactive object. A pump is configured for circulating the fluid within at least one of the outer container and the at least one inner container.

Abstract: The insect water supply system is configured to prevent the insects (such as crickets) from self-contaminating the water supplied to the insects' rearing enclosure. The system is designed so that the insects drink in an inverted (i.e. upside down) and elevated position—consequently the insects' feces fall downward toward the ground and away from their water source—and therefore do not contaminate the insects' water supply.

Abstract: A drinking bucket for feeding livestock a liquid food comprises a holding area configured to to hold the liquid food the holding area further configured to connect to at least one teat. An activity sensor for detecting sucking activity on the at least one teat is connected to an electronic control and configured to evaluate signals from the activity sensor and at least one of a remote data transmission apparatus and a display apparatus connected to the electronic control.

Abstract: A tracking and location system having an applicator including a syringe with a needle, a tracking unit having a chip, a wireless transponder, and a power supply configured to power the tracking unit. The syringe includes the needle configured to be inserted into and through skin and eject the tracking unit therethrough. The tracking unit includes the chip and the wireless transponder which are in communication with a software application hosted on a mobile device. A location of an animal with the tracking unit implanted, preferably a pet, is viewable on a display of the mobile device.

Abstract: A device to deter an animal from resting on furniture having a seating area comprises one or more sections of a rigid half-tubular form to be placed on the seating area, backrest, arm, and/or side of the furniture wherein the sections have a combined length to span approximately a width of the seating area, backrest, arm, or side. The half-tubular form can have the shape of an inverted half-cylindrical shape, a rectangular shape, a triangular shape, or a non-uniform relief shape wherein flat edges of the form are placed on the seating area, backrest, arm, or side of the furniture.

Abstract: The invention is a novel pet scratching device, particularly for cats, wherein a proprietary catnip formula is applied to corrugated cardboard inserts in the pieces of the device. Multiple pieces can be connected to one another like a jigsaw puzzle, and the pieces can contain varying shapes of corrugated inserts, as well as scratching or grooming accessories affixed thereto.

Abstract: An edible pet dental treat comprised of a substantially hard edible material formed into ribs having channel portions for cleaning pet teeth as it is being chewed. The edible treat is comprised of a plurality of ribs/channels formed on two sides of a bulb portion. The present invention also has first and second end portions with protrusions for massaging and scraping the tongue of the pet.

Abstract: A pet toy holds another item that can be chewed upon by a pet. The pet toy holds the item with a flexible retainer disposed within and protected by a central hub. The central hub can be provided with different external shapes including a round ball shape, an oval football shape, a flattened frisbee shape, an elongated bone shape, or a star shape with a plurality of arms. The central hub is configured to secure the retainer and protect the retainer from damage from the pet during use. The retainer can be a plurality of flexible fingers. The pet toy can have a plurality of arms projecting from the central hub. The central hub extends both above and below the arms to allow the pet to firmly hold the toy against the ground in a secure arrangement for both chewing on an arm of the pet toy and for chewing on a chew toy or edible item held by the pet toy.

Abstract: A process of making a reinforced elastomer and toy for pet made from same. The elastomer body may include rubber, thermoplastic resin, and elastomeric polyvinyl chloride. The elastomeric material is reinforced with fibers. Flavoring agents are mixed in the elastomeric body to produce a compression resistant and long-lasting scented body with durable fragrance. The fibers may be bonded to an outer surface of the elastomeric material.

Abstract: Disclosed is an absorbent article for pet animals. The article has a longitudinal direction, a transverse direction, a body-facing surface, a non-body-facing surface and first and second ends opposed to each other in the longitudinal direction. The article includes: a tail facing area facing a pet animal's tail; a first section to cover one side of a pet animal's rump, extending from the tail facing area to the first end; a second section to cover the other side of the pet animal's rump, extending from the tail facing area to the second end; and an absorbent core disposed between the first and second sections.

Abstract: A pet monitoring system includes a pet activity server having a pet database defining preliminary schedule for a variety of pets. A pet owner can obtain the preliminary schedule via an owner device and customize configuration settings for one or more pet devices based on the preliminary schedule and one or more modifications made thereto by the owner. The modifications may be based on modifications made to the preliminary schedule by additional owners and stored within the pet activity server within a community database. In certain aspects, the pet devices may automatically control one another based on the pet's interaction with a given device.

Abstract: Embodiments of the present disclosure relate to communication assemblies for animal health sensors. A communication assembly according to the disclosure can include: a network transceiver mounted on a circuit board; an antenna electrically coupled to the circuit board; and a resinous material encapsulating the antenna and the network transceiver therein, wherein the antenna is configured to transmit signals from the network transceiver through the resinous material; and a casing encapsulating at least the network transceiver, the antenna, and the resinous material therein, wherein the casing includes a plastic or ceramic material.

Abstract: The sex of embryos in eggs is influenced or controlled through the application of light having selected wavelengths and heat in order to promote the development of embryos of a selected sex. An incubating device is provided having an interior cavity that can be sealed from an outside, and having a plurality of lighting elements disposed in the interior cavity. Eggs are disposed on trays, and pre-determined environmental conditions are applied to the interior cavity to promote hatching of the eggs. Concurrently with the application of the environmental conditions, the eggs are irradiated according to pre-determined lighting conditions having wavelengths substantially concentrated in selected ranges In some embodiments, the temperature of the incubator is kept above or below the optimal incubation temperature.

Abstract: The present invention relates to genetically-edited swine comprising an introgressed heterologous nucleic acid sequence in the RELA gene. In particular it relates to genetically-edited swine comprising an introgressed warthog allele in the RALA gene of domestic pigs. The invention also related to methods of producing such swine, and cells derived from swine having such introgressed sequences.

Abstract: Duchenne muscular dystrophy (DMD), which affects 1 in 5,000 male births, is one of the most common genetic disorders of children. This disease is caused by an absence or deficiency of dystrophin protein in striated muscle. The major DMD deletion “hot spots” are found between exon 6 to 8, and exons 45 to 53. Here, a “humanized” mouse model is provided that can be used to test a variety of DMD exon skipping strategies. Among these are, CRISPR/Cas9 oligonucleotides, small molecules or other therapeutic modalities that promote exon skipping or micro dystrophin mini genes or cell based therapies. Methods for restoring the reading frame of exon 44 deletion via CRISPR-mediated exon skipping in the humanized mouse model, in patient-derived iPS cells and ultimately, in patients using various delivery systems are also contemplated. The impact of CRISPR technology on DMD is that gene editing can permanently correct mutations.

Abstract: Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized a proliferation-inducing ligand gene. Non-human animals and cells that express a human or humanized a proliferation-inducing ligand protein from an endogenous a proliferation-inducing ligand locus are described.

Abstract: Mice that comprise a replacement of endogenous mouse IL-6 and/or IL-6 receptor genes are described, and methods for making and using the mice. Mice comprising a replacement at an endogenous IL-6R? locus of mouse ectodomain-encoding sequence with human ectodomain-encoding sequence is provided. Mice comprising a human IL-6 gene under control of mouse IL-6 regulatory elements is also provided, including mice that have a replacement of mouse IL-6-encoding sequence with human IL-6-encoding sequence at an endogenous mouse IL-6 locus.

Abstract: A sieving device is described. The sieving device includes a sieve surface attached to a sieve rim. A set of openings is formed in the sieve surface so as to define a set of pathways extending through the sieve surface. The set of opening are defined by a length dimension that is greater than a width dimension. When the sieve surface is submerged in a liquid, a first pupa having a first cephalothorax width that is less than the width dimension is free to move through any one of the set of openings, and a second pupa having a second cephalothorax width that is greater than the width dimension is prevented from moving through the set of openings.

Abstract: A sieving method for separating insect pupae is described. The method may include causing an actuation system of a sieving apparatus to cycle between a first elevation and a second elevation to cyclically submerge a sieve surface of a sieving device in a liquid held within a basin so as to separate a population of insect pupae present in the sieving device with respect to size. The method may also include causing actuation of one or more valves to drain the liquid from the basin in order to retrieve a first part of the population of insect pupae.

Abstract: A sieving device is described. The sieving device includes a sieve surface attached to a sieve rim. A set of openings is formed in the sieve surface so as to define a set of pathways extending through the sieve surface. The set of opening are defined by a length dimension that is greater than a width dimension. When the sieve surface is submerged in a liquid, a first pupa having a first cephalothorax width that is less than the width dimension is free to move through any one of the set of openings, and a second pupa having a second cephalothorax width that is greater than the width dimension is prevented from moving through the set of openings.

Abstract: A combination paddle and fishing rod device is disclosed. The device may incorporate a single ended paddle or double ended paddle. In any embodiment, the device allows a fishing reel to be mounted to the shaft of the paddle. The shaft forms a portion of the fishing rod supporting one or more eyelets for guiding fishing line from a fishing reel mounted to the shaft. In one embodiment, the eyelets are connected to the shaft and or an oar blade. In another embodiment, a short fishing rod section having one or more eyelets is connected to the shaft. The device is configured to permit fishing while a user propels a watercraft.

Abstract: A winding machine for winding fishing line from a spool onto the reel of a fishing rod is disclosed. The winding machine incorporates a novel spring-loaded tongue that is adapted to provide a light pressure onto the fishing line as it is wound onto the reel thereby preventing backlash. The disclosed winding machine is portable and can be field-deployed on either the wall of a boat or on any other convenient, reasonably flat surface.

Abstract: Fishing line dispensing apparatuses for loading fishing line onto a reel, can include a base operable to hold a spool of fishing line, a cap detachably associated with at least a portion of the base, and one or more securing elements coupled to the base. The securing elements can be operable to releasably secure the base to a shaft of a fishing rod. The base of a fishing line dispensing apparatus can additionally include a spool retention surface disposed at a bottom end of the base and a sidewall connected to and extending in a substantially orthogonal direction away from the spool retention surface.

Abstract: A powered jigging device has a support frame, and a rod carrier that pivots in a first working plane while holding a fishing rod. A motor carrier is movably coupled to the support frame in a manner allowing constrained motion of the motor carrier in a parallel second working plane. A motor on the motor carrier drives an eccentric about a rotational axis of the motor. The eccentric is engaged with a mating feature the rod carrier at a position radially spaced from the pivot axis such that said driven revolution of the eccentric normally pivots the rod carrier upward and downward about said pivot axis, while the available constrained motion between the motor carrier and the support frame accommodates freewheeling operation of the motor when a caught fish pulls a front end of the rod carrier into a lowered position via tension in the fishing line.

Abstract: A fly-fishing reel having an integrated incremental meter device along with a modular weight system for customizing the weight of the fly-fishing reel in order for an angler to use the fly-fishing reel with a variety of fly rods and still maintain a desired balance point. The modular weight system allows the balance point of the rod and fly-fishing reel to be adjusted. The incremental metering device is adapted for keeping a tally of selected data, such as, though not limited to the number of fish caught or released.

Abstract: The present invention relates to an insect trap and, more specifically, to an insect trap which uses UV LEDs as light sources for luring insects and is capable of efficiently radiating luring light. The insect trap according to the present invention comprises a UV LED installation part having a plurality of UV LED light sources installed at intervals on the edge of the outer side surface thereof, and a trap part disposed adjacent to the UV LED installation part. The center lines of the ultraviolet light radiation areas of the UV LED light sources installed on the UV LED installation part are arranged substantially radially, extending outward from the center of the insect trap.

Abstract: A cockroach trap includes a case including an opening and first and second compartments; a guide assembly disposed above the first compartment and including a channel communicating with the opening, and a bossed hole communicating with the channel; an open reservoir releasably disposed in the first compartment; a bait passageway in an upper portion of the reservoir and communicating with both the channel and the reservoir; an entrance sensor disposed proximate the channel; a pivotal trigger disposed above the second compartment and including a projection; and an air canister releasably disposed in the second compartment and including a plunger engaged with the projection, a nozzle, and a line having two ends connected to the nozzle and the bossed hole respectively. After the entrance sensor is activated, the projection presses the plunger to open the nozzle, thereby communicating the nozzle with the air canister.

Abstract: An electrically powered infrared based thermal weed control system. A housing has a downwardly facing chamber. At least one electrically powered infrared heating element is mounted within the chamber. A source of electrical power is electrically coupled to the electrically powered infrared heating element. A control assembly varies the electrical power to the electrically powered infrared heating elements and the heat generated for controlling undesired vegetation there adjacent using targeted infrared radiation emitted by the electrically powered infrared heating element.

Abstract: A trap 1 has a frame 3, a striking bar 5 connected to the frame for killing a mouse or rat and a retaining bracket 7 attached to the striking bar, which is blocked in standby position by a blocking pawl 11 which can be released by an actuating element 13. A spring 9 is present between the striking bar and the frame, which striking bar hits the frame after activation. The trap is provided with a first sensor 17 which determines whether the striking bar is present in the standby or activated position, and a second sensor 19 which determines whether a mouse is present between the frame and the striking bar or not. A transmitter periodically sends the status of the sensors. The trap can determine three situations with the two sensors: standby, tripped and tripped with a mouse in the trap. This allows the status of the trap to he properly monitored.

Abstract: The present invention relates to a system for detecting and predicting rats and mice infestations. The system comprises a plurality of rechargeable traps, and a receiver unit configured for receiving a monitoring data signal from the rechargeable traps. The receiver unit comprises a processor and is operatively connected to a database. The database is adapted to store multiple database entries representing a value of a parameter related to rats and mice infestations at various points in time. The processor is programmed to perform a univariate and/or multivariate analysis of the database entries to detect and predict rats and mice infestations in a predefined geographical area.

Abstract: The present invention relates to an automatic rechargeable trap comprising a spring driven and/or gas pressure driven killing means; and species monitoring means configured for determining the species by monitoring the degree of advancement of the killing means during an individual triggering.

Abstract: The present invention relates to a gas delivery device comprising a gas releasing molecule and a gas permeable membrane. The invention also relates to the use of the gas delivery device for delivery of gas to an extracorporeal transplant, extracorporeal cells, a brain-dead transplant donor or foodstuff and in therapy. The invention further relates to the use of a gas permeable and liquid and solid impermeable membrane to separate a gas releasing molecule and its non-gaseous degradation products from an extracorporeal transplant, extracorporeal cells, a brain-dead transplant donor or foodstuff.

Abstract: Disclosed herein is a device for machine perfusion of an organ that includes a chamber including an organ support platform for supporting an organ and a perfusion circuit for providing an oxygenated perfusion fluid to the organ and carrying oxygen-depleted perfusion fluid away from the organ. The organ support platform includes perforations for fluid drainage. In some examples, the organ support platform is substantially horizontal. The device also includes a pump for circulating the perfusion fluid through the perfusion circuit, an oxygenating device in the perfusion circuit to oxygenate the perfusion fluid, and a temperature regulator for controlling the temperature of the perfusion fluid in the perfusion circuit. The device in some examples also includes a vascular perfusion cannula through which the perfusion fluid can flow to an organ placed on the organ support platform. Also disclosed are methods of perfusing an organ utilizing the machine perfusion devices.

Abstract: A sustained release pheromone preparation for controlling a pest insect contains, as sex pheromone components, an unsaturated aliphatic acetate and an unsaturated aliphatic alcohol having a structure where the acetyl group of the acetate is replaced with a hydrogen atom, wherein a ratio between the acetate and the alcohol in the mixture solution contained in the sustained release pheromone preparation can be kept constant throughout the effective action period. More specifically, the preparation includes a mixture solution containing the unsaturated aliphatic acetate and the unsaturated aliphatic alcohol in a weight ratio of 10:90 to 99.5 to 0.5 and a container for enclosing the mixture solution, the container containing, as at least a part of the container, a membrane of a polyester corresponding to Formula (I) below, a copolymer thereof, or a polymer blend of the polyester or copolymer with a biodegradable polyester.

Abstract: The invention provides analogues of (S)-germacrene D analogue which have improved insect repellent properties compared to (S)-germacrene D analogue or which have insect attractant properties.

Abstract: A method of sterilizing a material, said method comprising the steps of: a) providing a sterilizing composition comprising (i) peracetic acid and (ii) a stabilizer selected from the group consisting of citric acid, isocitric acid, aconitic acid and propane-1,2,3-tricarboxylic acid; b) introducing such sterilizing composition into a hot gaseous stream to produce a peracetic acid vapor; and c) contacting such peracetic acid vapor with the material to be sterilized. The use of such an organic acid stabilizer results in an unexpected reduction in the amount of residue deposited on the heating surface employed to vaporize the sterilizing composition.

Abstract: The present disclosure relates to a composition for the destruction of microalgae or mosses. The composition for the destruction of microalgae or mosses may suppress the growth and proliferation of microalgae when treated in moss cultivation facilities, marine microalgae cultivation facilities, areas in which green or red tide is occurring, or areas in which green or red tide is expected to occur, thereby preventing damage caused by the green or red tide.

Abstract: The present invention is concerned with the use of the natural product Ilicicolin H as an agricultural fungicide, compositions comprising Ilicicolin H, and the use of such compositions to treat, control or prevent fungal infection in agricultural products.

Abstract: The present invention provides a fungicide composition for agricultural and horticultural use, comprising compound A represented by formula (1) (in formula (1), Xs each independently represents a halogeno group or a C1-6 alkyl group; n represents a number of Xs and is an integer of 0 to 5; X? represents a halogeno group; R1, R2 and R3 each independently represents a C1-6 alkyl group, a C1-6 alkoxy group or a hydroxyl group; A1 and A2 each independently represents a nitrogen atom or a carbon atom), and at least one compound B selected from the group consisting of pydiflumetofen, pyraziflumid, isofetamid, tolprocarb, fluxametamide, broflanilide, tiadinil, fenoxanil and triflumezopyrim.

Abstract: The present invention relates to the use of phenylpyrimidines of formula (I) or their agriculturally acceptable salts or derivatives as herbicides, wherein the variables are defined according to the description, specific phenylpyrimidines of formula (I), processes and intermediates for preparing the phenylpyrimidines of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one phenylpyrimidine of the formula (I) to act on plants, their seed and/or their habitat.

Abstract: Compositions and methods of using a pesticidal mixture PM that includes at least one compound of formula I defined above, an insecticide and a fungicide for protecting crop, plant propagation material, or soil or water in which the plants are growing, against attack or infestation by invertebrate pests and/or phytopathogenic fungi are described. Also described is a seed treatment composition that includes the pesticidal mixture PM, as well as seeds treated using the pesticidal mixture PM or the seed treatment composition. Methods for controlling invertebrate pests and/or phytopathogenic fungi on crop plants are described that include contacting the plant or the plant propagation material; the pest or its food supply, habitat or breeding ground; and/or the fungi or habitat, with an effective amount of the pesticidal mixture PM or the seed treatment composition. Binary mixtures of a compound of formula I and a second pesticidal component are also described.

Abstract: Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, and their uses as insecticides.

Abstract: New heterocyclic trifluoroalkenyl compounds having formula (I): Het-S(O)n—(CH2)m—CF?CF2?? (I) agronomic compositions containing them and their use for the control of nematodes in agricultural crops, are described.

Abstract: Antimicrobial resistance is rising at an alarming rate. The methylerythritol phosphate (MEP) pathway is a metabolic pathway that produces the isoprenoids isopentyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). Notably, the MEP pathway is present in bacteria and not mammals, which made the enzymes of the MEP pathway attractive targets for discovering new anti-infective agents due to reduced chances of off-target interactions leading to side effects. The biophysical properties of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) and 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) were determined to aid discovery of novel inhibitors. Thermal shift screening was used as an initial filter to narrow down a library of compounds with thermal shifts greater than 1° C., which could indicate binding to the IspD and IspE enzymes. Follow-up studies were performed using isothermal titration calorimetry and enzymatic inhibition assays.

Abstract: The invention relates to novel compounds of the formula (I) in welcher R1, R2, R3, A1, X and n have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.

Abstract: This disclosure relates to sporicidal compositions and uses thereof. The sporicidal compositions include one or more cationic steroidal antimicrobials (CSAs). The sporicidal compositions may be applied to an object to kill or deactivate bacterial spores contacting the sporicidal composition. The object may be a food product, food processing equipment, industrial equipment, or healthcare facility objects. The sporicidal composition may be administered to a subject that has, is suspected to have, or is at risk for an infection associated with spore-forming bacteria.

Abstract: Insecticide composition wherein the active ingredient comprises the combination of a neonicotinoid insecticide, thiamethoxam as synthetic insecticide molecule, and at least one synergistic agent, which is chosen among the insect repellent agents such as DEET and/or IR3535® and present at a molar ratio of said synergistic agent to thiamethoxam comprised between O.OOI and 0.2 in the composition. Synergistic effect is observed at low doses. Use of the insecticide composition wherein said composition is sprayed or deposited on, or impregnated to a support, such as net, fabrics, cloth or tent, in the fight against insects which are harmful to human, to animals and/or to crops, and in particular against pyrethroid, carbanate and/or organophosphate resistant mosquitoes.

Abstract: The invention provides a method of treatment of a human subject to combat infestation by multicellular ectoparasites with exoskeletons, in particular head lice, which method comprises topically applying to said subject a first and a second pediculicide, said first pediculicide being a carbamate or organophosphate pediculicide and said second pediculicide being a pyrethroid or pyrethrin pediculicide, characterized in that said second pediculicide is applied between 15 minutes and 12 hours after the application of said first pediculicide.

Abstract: A prepared organic acid salt solution for insect prevention is disclosed. A diluted aqueous solution of an organic acid salt is prepared to have a certain concentration, and then mixed with diatomaceous earth in a specific weight ratio to obtain a protection solution containing a silicate. The protection solution is uniformly sprayed on the surfaces of plants for avoiding insects to protect plants.