Abstract: Method and device for optimizing the measurement accuracy in vivo when measuring invasive blood pressure using a fluid-filled catheter-manometer system including a medical signal processing device; a catheter; a pressure line connected to the catheter; a pressure transducer-flush system unit connected to the pressure line and to a pressurised storage bag, and having an integrated pressure transducer and an integrated flush system, the pressure transducer having a membrane to convert a pressure signal into an electric signal that is transmitted to the medical signal processing device, the flush system ensuring that a continuous flush from the storage bag to the catheter is maintained, the flush system having a manually operable element configured for temporarily, briefly opening and closing the flush system.

Abstract: A device non-invasively measures aortic flow in the subdiaphragmatic region in a small laboratory mammal. The device includes a device for plethysmography of the thorax by inductance measurement, having two electrically conducting, extendible coils rigidly attached to an elastic garment that is adjustable to the torso of the mammal, a device for acquiring the signal from variation in the cross-section of each coil, and a processor configured to calculate the instantaneous subdiaphragmatic aortic flow of the mammal from the signals from the variation in cross-section of each coil and from a functional model of the cardiorespiratory system. The exchanges of blood between the thorax and the rest of the body of the mammal include an output of blood via the abdominal aorta in the subdiaphragmatic region and an input of blood via the inferior vena cava.

Abstract: The present application discloses a blood pressure measurement device, includes: a blood pressure measurement body configured to measure blood pressure based on photoplethysmogram (PPG), and a calibrator configured to measure blood pressure values based on Korotkoff sounds. The calibrator is further configured to provide initial calibration parameters to the blood pressure measurement body, and the blood pressure measurement body is further configured to collect an ECG signal and a PPG signal, calibrate a PPG parameter-blood pressure equation according to the initial calibration parameters, and calculate a blood pressure value according to the PPG parameter-blood pressure equation.

Abstract: The present invention provides a wrist-worn blood pressure monitor that is worn around a wrist. The wrist-worn blood pressure monitor according to the present invention includes a wrist cuff including a wrist strap so as to be worn around a wrist, a sensor provided at the wrist cuff in order to measure blood pressure, and a tightener provided at the wrist cuff in order to selectively tighten the wrist cuff so that the wrist cuff compresses the wrist. According to the present invention, a user is able to conveniently measure his/her blood pressure whenever there is a need to measure the blood pressure, and the accuracy of the measured blood pressure is increased since the wrist-worn blood pressure monitor is securely tightened around the wrist.

Abstract: A sensor includes a probe that acquires a blood light absorber concentration in a subject and a cuff that acquires a non-invasive blood pressure of the subject. In the sensor, the probe is configured to be attached to a first portion of a digit of the subject, and the cuff is configured to be attached to a second portion of the digit, the second portion being located on a periphery side with respect to the first portion.

Abstract: A method for event detection in a user-wearable device includes receiving, from a first sensor implemented in the user-wearable device, photoplethysmogram (PPG) signals; processing, at a processor, the PPG signals to obtain PPG signal samples; detecting, at the processor, beats in the PPG signal samples; dividing the PPG signal samples into PPG signal segments; extracting at least one inter-beat interval (IBI) feature in each PPG signal segment; classifying, at the processor, each PPG signal segment using the extracted IBI feature associated with the PPG signal segment and using a machine learning model; in response to the classifying, generating, at the processor, an event prediction result for the PPG signal segment based on the extracted IBI feature; and displaying the event prediction result at the user-wearable device. In another embodiment, the method further includes extracting morphology based features.

Abstract: The present disclosure provides a vital sign measuring device and method that may measure a heart rate signal of a living body in a motion state. The method comprises detecting two different signals, using an adaptive noise removal algorithm for removing noise from the two signals, and obtaining a more accurate heat rate signal after a certain operation.

Abstract: In illustrative implementations of this invention, a photoplethysmographic device measures variations of light that is reflected from, or transmitted through, human skin. In some implementations, the device includes a camera that takes the measurements remotely. In others, the device touches the skin during the measurements. The device includes a camera or other light sensor, which includes at least orange, green and cyan color channels. In some cases, such as a contact device, the device includes three or more colors of active light sources, including at least orange, green and cyan light sources. A computer analyzes the sensor data, in order to estimate a cardiac blood volume pulse wave. For each cardiac pulse, a computer detects the systolic peak and diastolic inflection of the wave, by calculating a second derivative of the wave. From the estimated wave, a computer estimates heart rate, heart rate variability and respiration rate.

Abstract: An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall.

Abstract: A method of mapping cardiac restitution includes: receiving a plurality of EP data points including location and restitution data; identifying a subset of the EP data points forming an EP data point cluster; fitting a restitution curve to the restitution data of the EP data points forming the cluster; and identifying at least one restitution metric for a region of the cardiac surface corresponding to the cluster from the restitution curve. The restitution curve can be an exponential function using quiescent interval data (e.g., DI and/or CL) as the independent variable and cardiac repolarization activity data (e.g., APD, ARI, and/or EGM width) as the dependent variable. The parameters of the exponential function can be determined by optimizing a cost function. A graphical representation of the restitution metric can also be output on a three-dimensional model of the cardiac surface.

Abstract: The present invention concerns a system (100) for analyzing electrophysiological data, especially intracardial electrogram data, the system (100) comprising a data processing and control unit (15) for processing the electrophysiological data, a data output unit comprising a data output screen (324) for displaying results of electrophysiological data analysis, wherein the data processing and control unit (15) being configured to receive electrophysiological data obtained from a mapping catheter assembly (110, 111) that comprises an electrode assembly (120, 80) with a plurality of n electrodes (82), each electrode (82) configured for measuring electrophysiological data in the form of electrogram signals.

Abstract: Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.

Abstract: Disclosed is a system for estimating arterial blood pressure. The system includes a heartbeat detection module configured to receive an electrocardiogram signal, and detect one or more QRS complexes of the electrocardiogram signal. The system also includes a photoplethysmographic sensor module configured to trigger a light emitter, thereby generating a plurality of samples of a photoplethysmographic signal. Further, the system includes a blood pressure calculation module configured to receive information about the detected one or more QRS complexes and the plurality of photoplethysmographic signal samples, and calculate at least one blood pressure value based on a pulse arrival time period between the electrocardiogram and the photoplethysmographic signal.

Abstract: A system having a wearable devices that, together with a cognitive model, are able to analyze a person to determine if they are in the flow and/or guide the person to get into the flow are disclosed. The system and processes help persons to find their unique formula to achieve flow. By using a cognitive AI engine, the system can describe a space of mental states and the actions that cause transitions between them for each individual.

Abstract: A method and system for operating a neural feedback system is disclosed. The method includes recording brain waves of a user, recording sensor data measuring at least one of a physical state or an activity of the user, and generating recorded context-based brain wave information by detecting correlations between the recorded brain waves and the recorded sensor data. The method further includes identifying recorded context-based brain wave patterns in the recorded context-based brain wave information and associating at least one rule of at least one electronic device with at least one recorded context-based brain wave pattern.

Abstract: Disclosed is apparatus including a power source, an ECG front end, a processor, and a computer-readable medium. The ECG front end is configured to receive a signal corresponding to a cardiac waveform, and the computer-readable medium is encoded with instructions which, when executed by the processor, cause the apparatus to (a) determine a first temporal window during which a first instance of a first portion of a cardiac cycle is expected to appear in the cardiac waveform (b) at a start of the first temporal window, apply a first amount of power from the power source to the ECG front end, and (c) at an end of the first temporal window, at least partially reduce an amount of power applied from the power source to the ECG front end.

Abstract: This application relates to the field of wearable devices and provides a dominant eye determining method and device. A method comprises: obtaining first sensory information of a first eye of a user; and determining whether the first eye is a dominant eye according to the first sensory information and reference information. The method and device help other devices worn by a user to perform automatic set-up according to a determining result, thereby improving user experience.

Abstract: An electrode padset and a method of using the electrode padset are disclosed herein. The electrode padset is a single unit, consisting of multiple patient-contacting conductive pads arranged on a single piece of material. The padset is comprised of a plurality of conductive pads, at least one conductive pad adapted to emit an electrical signal and at least one other conductive pad adapted to receive an electrical signal, and an electrically conductive material coupling the conductive pads.

Abstract: A method of imaging an implant device in a computing device is provided. The computing device includes a processor interconnected with a memory and a display. The method includes, at the processor: obtaining a first magnetic resonance (MR) image of a patient tissue, the first MR image containing a first magnetic field strength indicator; responsive to the implant device being inserted in the patient tissue, obtaining a second MR image of the patient tissue, the second MR image containing a second magnetic field strength indicator smaller than the first magnetic field strength indicator; registering the second MR image with the first MR image; generating a composite image from the first MR image and the second MR image; and presenting the composite image on the display.

Abstract: Methods and devices for magnetic resonance imaging are provided. In one aspect, a method of magnetic resonance imaging includes: for each scanning step in a scanning sequence for a subject, determining a longitudinal magnetization intensity of a characteristic tissue of the subject according to a current running condition of the scanning sequence, obtaining an inversion time corresponding to a characteristic tissue suppressing pulse to be generated according to the determined longitudinal magnetization intensity, generating the characteristic tissue suppression pulse, generating an imaging pulse sequence when the inversion time elapses after generating the characteristic tissue suppression pulse, and receiving an echo signal from the subject, the echo signal corresponding to the generated imaging pulse sequence. The method can also include reconstructing an image of the subject according to the received echo signals when the scanning sequence finishes the scanning steps.

Abstract: The present invention relates to a means for retaining stably a posture of a subject or a patient during a medical practice, namely, a medical posture retainer having a mat 1 and a core member. The mat 1 is composed of an airtight bag 2 and a cushion layer 3. The airtight bag 2 is a cover of the mat 1 supporting the human body and retaining the posture. The airtight bag 2 has a gas barrier property, and an exhaust valve for deflation is attached to the airtight bag 2. The cushion layer 3 is formed of strata of particles P filled in the airtight bag 2. The core member includes a plate-like support 4 that is attached to a (inner or outer) side face of the airtight bag 2 to keep a certain rise height of the airtight bag 2, and a stopper 6 that is attached to the upper face and the lower face of the airtight bag 2 so as to restrict the rise height of the airtight bag 2.

Abstract: Markers and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes one or more photosensitive diodes for transforming light pulses striking the marker into electrical energy, one or more antennas, and a switch coupled to the photodiodes and antennas such that the light pulses cause the switch to open and close and modulate radar signals reflected by the marker back to a source of the signals. The antenna(s) may include one or more wire elements extending from a housing, one or more antenna elements printed on a substrate, or one or more chip antennas. Optionally, the marker may include a processor coupled to the photodiodes for identifying signals in the light pulses or one or more coatings or filters to allow selective activation of the marker.

Abstract: Ingestible devices are disclosed that provide very high localization accuracy for the devices when present in the GI tract of a body. Related systems and methods are also disclosed.

Abstract: A hub for an optical shape sensing reference includes a hub body (606) configured to receive an elongated flexible instrument (622) with a shape sensing system coupled to the flexible instrument within a path formed in the hub body. A profile (630) is formed in the hub body in the path to impart a hub template configured to distinguish a portion of the elongated flexible instrument within the hub in shape sensing data. An attachment mechanism (616) is formed on the hub body to detachably connect the hub body to a deployable instrument such that a change in a position of the hub body indicates a corresponding change in the deployable device.

Abstract: A system including a sensor, a mobile device, and a computer system is disclosed. The sensor is configured to detect physiologic data from the body of the patient. The mobile device includes a patient data input device. The computer system, communicatively coupled to the mobile device, includes a patient record indicating: patient data comprising a plurality of patient activities, and detected physiological data received from the sensor via the mobile device. The computer system is configured to identify an unhealthy physiological data value from the detected physiological data of the patient record, correlate the unhealthy physiological data value to a patient activity of the patient data, select a therapeutic recommendation to address the unhealthy physiological data value, and transmit the selected therapeutic recommendation to the patient, via the mobile device, at a future time associated with the patient activity correlated to the unhealthy physiological data value.

Abstract: User interface (UI) apparatus and associated logic and methods for use with a blood analyte sensor. In one embodiment, the blood analyte sensor comprises an implantable blood glucose sensor, and the UI and associated logic are configured to receive and store user-specified parameters for operation of the blood analyte sensor and/or associated receiver. In one exemplary implementation, the UI and associated logic are configure to selectively implement various user interface regimes, including display of various analyses of current blood analyte level data and/or historical blood analyte level data, as well as prompting the user to take actions. The exemplary implementation is also optionally configured to identify and mitigate data errors.

Abstract: A method to generate orthotic product recommendations for users includes receiving interactions from a user including identification of one or more extremity areas of the user's body, the one or more extremity areas relevant to selection of one or more orthotic products. On-screen cues and interactions are provided to assist in positioning of the one or more extremity areas relative to one or more imaging sensors. Scan data is received from the one or more imaging sensors. A model of the one or more extremity areas is generated based on the scan data including estimating one or more complete circumferences of the one or more extremity areas. One or more orthotic products are identified based on a comparison of the model of the one or more extremity areas and one or more factors associated with the user and a plurality of orthotic products. A recommendation is provided that includes the one or more orthotic products.

Abstract: Accuracy enhancing systems, devices and methods are provided using data obtained from inertial measurement units (IMUs). IMUs are provided on one or more of a patient, surgical table, surgical instruments, imaging devices, navigation systems, and the like. Data from sensors in each IMU is collected and used to calculate absolute and relative positions of the patient, surgical table, surgical instruments, imaging devices, and navigation systems on which the IMUs are provided. The data generated by the IMUs can be coupled with medical images and camera vision, among other information, to generate and/or provide surgical navigation, alignment of imaging systems, pre-operative diagnoses and plans, intra-operative tool guidance and error correction, and post-operative assessments.

Abstract: A gait pathology detection and monitoring system, and method using rotation, scale, and offset invariant dynamic time warping (RSOI-DTW).

Abstract: This disclosure relates to systems and methods to analyze gait, balance or posture information extracted from data collected by one or more wearable and connected sensor devices with sensors embedded therewithin. The embedded sensors include a three-axis accelerometer, a three-axis gyroscope and an array of pressure sensors. Sensor data detected by the sensors can be received by a mobile computing device, which can analyze the sensor data to identify a pattern related to gait, balance or posture within the sensor data; and apply a statistical/machine learning-based classification to the pattern related to gait, balance or posture to as sign a clinical parameter to the pattern characterizing a risk of a slip, trip and fall event.

Abstract: A system and method for monitoring the running technique of a user undertaking a physical activity is described. The system comprises: a garment worn by the user incorporating a sensor for the detection of a parameter relating to the movement of the pelvis of the user; a processing unit configured to receive information about the parameter from the sensor, to compare the parameter with an aspect of a biomechanical model, and to determine if a feedback response is required; and means for providing the feedback response to the user. The method comprises the steps of: measuring a parameter relating to the movement of the pelvis of the individual; comparing the parameter with a biomechanical model to determine whether a feedback response is required and providing a feedback response if required.

Abstract: A method and apparatus is proposed to estimate the aortic pulse transit time (PTT) from only time intervals measured between fiducial points of the longitudinal balistocardiogram (BCG) without the need to apply any sensor to the area where the arrival of the arterial pulse waveform is to be detected. From the longitudinal BCG of a subject, which can be obtained by means of sensors integrated in a single element with which the subject's body comes into contact, two fiducial points of the BCG waveform are detected in which one of the points is associated with the arrival of the arterial pulse wave to a zone proximal to the heart and the other is associated with the arrival of said arterial pulse wave to a distal zone, respectively. From the time interval between the two points, an estimate of the aortic (carotid-femoral) PTT is provided either directly or through a process of previous calibration.

Abstract: Embodiments of the present disclosure relate generally to devices and systems for administering pharmaceutical, monitored and/or biological agents via nebulization to a subject. In certain embodiments, the present disclosure provides devices, methods and systems for biometric and diagnostic data acquisition and patient monitoring before, during, and after the nebulization and administration of pharmaceutical, monitored and/or biological agents to a subject. In yet other embodiments, devices, systems and methods disclosed herein provide for delivery of agents where patients have an increased level of control over the delivery of their medication and by providing healthcare providers with meaningful and accurate biometric and diagnostic data during treatment.

Abstract: A neuromuscular, physiological, biomechanical, or musculoskeletal activity monitoring system for a subject is provided. The system includes a wearable inertial measurement unit including at least one accelerometer and/or at least one gyroscope. The system also includes a controller in communication with an output component. The controller is configured to: receive and process information from the inertial measurement unit representative of one or more physical actions performed by the subject; generate an inertial data set for the one or more physical actions based on the received and processed information; compare the generated inertial data set to reference data stored on computer readable memory in communication with the controller; and cause the output component to provide feedback including predictive injury information. The predictive injury information is based, at least in part, on the comparison between the generated data set and the reference data.

Abstract: The present disclosure envisages a device for tracking, monitoring and analyzing biophysical-activities of a user. The device includes a motion and activity sensing unit to sense and track motion, direction and acceleration of the biophysical-activities and generate a plurality of motion and activity related signals, a biosensor unit to sense and track a plurality of health parameters and generate a plurality of health related signals, a bio-mechanical tracking unit to sense a plurality of activity parameters including speed, count, axis, direction and position, and generate a plurality of bio-mechanical related signals, a signal conditioning unit to generate conditioned health data and conditioned bio-mechanical data based on the plurality of motion and activity related signals.

Abstract: Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior.

Abstract: Disclosed herein, among other things, are apparatus and methods for automated assessment and adjustment of tinnitus-masker impact on speech intelligibility during use of the tinnitus-masker. In various embodiments, a method of fitting a tinnitus-masker device for a patient is provided. The method includes using a speech intelligibility model to predict impact of therapy provided by the tinnitus-maker device on speech understanding of the patient. A parameter of the tinnitus-masker device is automatically adjusted during use to reduce the impact of the therapy provided by the tinnitus-maker device on speech understanding of the patient, according to various embodiments.

Abstract: A system, transceiver, and method for calculating and correcting levels (e.g., analyte levels) in a first medium (e.g., blood) using measurements from a second medium (e.g., interstitial fluid). In some embodiments, a transceiver may calculate an initial second medium level. The transceiver may calculate an initial second medium level rate of change (“ROC”) using at least the initial second medium level and past second medium level(s). The transceiver may calculate a first medium level using at least the initial second medium level and the initial second medium level ROC. The transceiver may calculate a subsequent second medium level. The transceiver may calculate an updated second medium level ROC using at least the initial second medium level, the subsequent second medium level, and past second medium level(s). The transceiver may calculate a corrected first medium level using at least the initial second medium level and the updated second medium level ROC.

Abstract: Various embodiments of a hermetically-sealed package and a method of forming such package are disclosed. The package can include a housing having an inner surface and an outer surface, and a non-conductive substrate hermetically sealed to the housing. The package can also include a light source disposed on a first major surface of the substrate and adapted to emit light through the first and second major surfaces of the substrate, and a detector disposed on the first major surface of the substrate and adapted to detect the light emitted by the light source.

Abstract: A monitoring system includes a surgical implant configured for implantation in vivo and having at least one sensing fiber configured to measure a preselected physiological parameter, and a receiving unit in wireless communication with the at least one sensing fiber and configured to receive measurements of the preselected physiological parameter. A surgical system includes an end effector having a plurality of fasteners, and a surgical implant securable to tissue via the plurality of fasteners. The surgical implant includes at least one sensing fiber configured to measure a preselected physiological parameter.

Abstract: An on-body insertion system is described. The on-body system includes a sensor in a first position being substantially parallel to an insertion surface. Activation of an actuator transitions the sensor to a second position. Wherein the transition imparts movement to the sensor that is substantially parallel to the insertion surface and the second position results in the sensing area being beneath the insertion surface.

Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Abstract: Provided is a transdermal microneedle array patch, including: a bottom cover; a top cover; a substrate disposed within the top cover; and a first probe and a second probe disposed between the bottom cover and the top cover and electrically connected the substrate. The first and second probes form an open circuit. While the bottom cover is combined with the top cover to form the transdermal microneedle array patch, the first and second probes form a closed circuit.

Abstract: Embodiments of the invention disclosed herein are directed to articles of clothing that allow for monitoring of different analytes (e.g., electrolytes and molecules) in human sweat during fitness activity, while training, or simply in everyday life. The clothing includes a sensor system completely integrated in textile such that every sensing part is made of textile fibers. The clothing is able to control, collect, analyze, and expel the sweat over time. The textile sensor allows a spontaneous absorption of body sweat directly from the skin, while it is produced, using the hydrophilic natural properties of the textile. Then, once adsorbed, the flux of sweat is controlled and guided through the textile using a gradient of the textile's hydrophilic properties. The sweat guided through the textile is analyzed through an electrochemical sensor woven into the textile. Finally, the sweat is collected in a reservoir and expelled for evaporation.

Abstract: The Dickerson medical meter assist diabetic people which manage their insulin levels and tells them the amount of insulin intake that they need at the time. The device uses a fingerprint sensor to read insulin levels and provides instructions if steps are needed to control blood sugar immediately. The Dickerson medical meter includes a USB port so that you can charger the internal battery and save readings for medical offices. The battery level indicator will let a user know when it is time for a recharge. The device can be used with liquid insulin. This device can also check your heart rate, temperature and oxygen levels.

Abstract: Various embodiments of a sealed package and a method of forming such package are disclosed. The package includes a housing, a substrate hermetically sealed to the housing, and a light source disposed on a first major surface of the substrate. The package further includes a detector disposed on the first major surface of the substrate and having a detecting surface. The package also includes a masking layer disposed on at least one of the first major surface and a second major surface of the substrate, where the masking layer includes a first aperture aligned with an emission axis of the light source in a direction orthogonal to the first major surface of the substrate. The masking layer further includes a second aperture aligned with a detection axis of the detector in a direction orthogonal to the first major surface of the substrate.

Abstract: This liquid sample measurement device is provided with: a lancet mounting part to and from which a lancet device having a skin contact section for puncturing skin can be attached and detached; a sensor mounting part to which a biosensor, which is spotted with blood that comes out from the punctured skin, can be attached; and a measurement part that uses the biosensor attached to the sensor mounting part to measure the amounts of substances in the blood. The liquid sample measurement device includes a feature that makes it necessary to replace a lancet device that has been attached to the lance mounting part and has punctured skin, each time a lancet device is used to puncture skin.

Abstract: A stimulus information compiling method for tests is disclosed comprising the following steps: selecting and using stimulus information which follows a statistics-normal distribution and is analyzed and measured by validity to form a stimulus information database (Q); reasonably setting at least one stimulus information to be a test including at least one test sequence, for a subject to make a selection according to his or her personal interests; comparing a test score of the subject with that of a valid sample person in a normal distribution model, thereby confirming the distribution of the subject in each cognitive dimension. A test score of the subject is compared with that of a valid sample person in a normal distribution model, thereby confirming the test result of the subject.

Abstract: Provided are a method and system for detecting frequency-domain cardiac information, the method comprising: acquiring moving images of a pupil from a subject; extracting a pupil size variation (PSV) from the moving images; extracting a heart rate variability (HRV) spectrum by performing a processing procedure including frequency-analysis of HRV; and calculating power of at least one of a plurality of frequency bands by analysis of the HRV spectrum.