Abstract: The present invention provides a surgical tracking system for assisting an operator to perform a laparoscopic surgery of a human body, said surgical tracking system comprising: a. at least one endoscope adapted to acquire real-time images of a surgical environment within said human body; b. a maneuvering subsystem adapted to control the spatial position of said endoscope during said laparoscopic surgery; and, c. a tracking subsystem in communication with said maneuvering subsystem, adapted to control the maneuvering system so as to direct and modify the spatial position of said endoscope to a region of interest.

Abstract: A system for controlling a display of image data is presented including a first imaging unit for capturing a first set of images and a second imaging unit for capturing a second set of images. The system also includes a display unit configured to display the image data in a picture-in-picture mode, such that the display unit displays the first set of images in a first panel having a first size and the second set of images in a second panel having a second size, where the first size is greater than the second size.

Abstract: There is provided an image processing device including an image information acquisition unit configured to acquire a captured image from an endoscope, an adjustment information acquisition unit configured to acquire color calibration information about color calibration performed in a display device on which the captured image is displayed, a transmission unit configured to transmit, to a printing device, print data corresponding to the acquired captured image, and a correction value acquisition unit configured to acquire a correction value used for performing, on the print data, correction that is corresponding to the color calibration of the acquired color calibration information.

Abstract: An optical assembly adapted to be positioned within an endoscope tip and having three modular camera units, comprising: a front modular camera unit defined by a front central axis and a first and second side modular camera units defined by first and second side central axes that are substantially parallel to one another and substantially perpendicular to the front central axis. Each modular camera unit further comprises a holder for housing an associated optical element and an image sensor in data communication with a corresponding printed circuit board. The front, first side and second side modular camera units are respectively positioned in first, second and third compartments of an assembly holder.

Abstract: A light transmitting medical instrument provides for the enhanced performance of medical procedures. The light transmitting medical instrument comprises a light pipe having a first end operatively coupled to a light source and a second end having a functional tip having at least two arms. A sliding closure sleeve is mounted about the light pipe. The sliding closure sleeve has a first end portion at which the sliding closure sleeve is fixed to the light pipe in a manner such that relative movement therebetween is prevented and a second end proximate the functional tip of the light pipe. The sliding closure sleeve further comprises a spring-like actuator finger grip that, when forced radially inward, causes the second end of the sliding closure sleeve to move toward the functional tip, thereby forcing the arms of the functional tip towards one another.

Abstract: An endoscope with a wide angle lens that comprises an optical axis that is angularly offset from a longitudinal axis of the endoscope such that the optical axis resides at an angle greater than zero degrees to the longitudinal axis. The wide angle lens system simultaneously gathers an endoscopic image field, the endoscopic image field at least spanning the longitudinal axis and an angle greater than ninety degrees to the longitudinal axis. The endoscope includes an optical lens system to at least partially even out the information density across an imaging surface area of the imager.

Abstract: The insertion apparatus includes: a linearly-extending insertion section main body, an outer tube covering the outer circumference of the insertion section main body, and an annular band member provided on the outer tube in such a manner as to meander on an imaginary circle on the outer tube whose center is the same as the central axis of the insertion section main body. The annular band member is configured to shrink in the direction along the imaginary circle and thereby secure the outer tube to the insertion section main body.

Abstract: The invention refers to a deflection movement transmission device comprising a control element (1) for effecting a deflection movement, the control element (1) having a pivot portion (11; 11?) that is supported on a head portion (31; 31?) of a base element (3) and is pivotable relative to the head portion (31; 31?) of the base element (3) for effecting a deflection movement; at least one movement transmission wire body (2, 2a, 2b) that is articulated to the pivot portion (11; 11?) of the control element (1); an elongate transmission guiding body (5) in the longitudinal direction of which the movement transmission wire body (2, 2a, 2b) is guided; and a bendable body (6) to be deflected that is seated at the end of the transmission guiding body (5), opposite to the control element (1), and to which the movement transmission wire body (2, 2a, 2b) is mounted in a manner spaced apart from a connection (61) to the transmission guiding body (5).

Abstract: Complex steerable catheter visualization and tissue manipulation systems and their methods of use are disclosed herein. The deployment catheter is articulated using various steering mechanisms. Tissue visualization is accomplished from the visualization hood at the distal end of the deployment catheter, the hood having an ability to expand and other features to facilitate visualization and articulation at the tissue surface.

Abstract: The overtube includes a slider within an overtube body, which guides an endoscope and a treatment tool. An endoscope-coupled part and a treatment tool-coupled part are provided inside the slider, and the slider has a dead zone where the forward and backward movement of either the endoscope or the treatment tool does not interlock with the movement of the other and a sensing zone where the forward and backward movement of either the endoscope or the treatment tool interlocks with the movement of the other. The overtube body includes a distal-end-side stopper and a base-end-side stopper that restrict the movable range of the slider. A length L from a coupling position of the endoscope to a distal end position of the overtube body and a length Ls from the coupling position of the endoscope to a distal end position of the endoscope are set to satisfy Ls?L.

Abstract: A cooling device according to the invention includes: a first flow channel configured so that a coolant passes; a first heat receiving portion; a first heat radiating portion arranged in the first flow channel; a first heat transferring portion configured to transfer heat from the first heat receiving portion to the first heat radiating portion; a second flow channel configured so that the coolant passes; a second heat receiving portion; a second heat radiating portion arranged in the second flow channel; and a second heat transferring portion configured having a longer length than the first heat transferring portion and transferring heat from the second heat receiving portion to the second heat radiating portion. The second heat radiating portion is configured having a larger surface area than the first heat radiating portion.

Abstract: An eye viewing device includes an imaging assembly having at least two optical components disposed along an optical axis of the device. An adapter is attachable to the device and is aligned along the imaging axis of the device, the adapter having at least one adaptive optical element configured for projecting an image of the ear along the imaging axis for viewing without modification to the device and enabling separate examination modes.

Abstract: The present invention relates to a fully integrated sterilizable one time use disposable tissue visualization device and methods for using such devices. Preferred embodiments of the invention facilitate the visualization of an internal tissue site while causing a minimum of damage to the surrounding tissue. Further preferred embodiments may allow for the delivery of fluids and other treatment to an internal tissue site.

Abstract: A near-eye display including a light source, an optical system, and a phase map including multiple pixels. The optical system is configured to receive illumination light from the light source and output the illumination light as an in-phase wavefront. Control logic of the near-eye display is coupled to variously program different phase patterns of the phase map at different times. The phase patterns are each to variously adjust phases of respective portions of the in-phase wavefront. For each of the phase patterns, the phase map is to form a different respective image in response to being illuminated by the in-phase wavefront.

Abstract: Systems and methods for efficiently obtaining optical coherence tomography (OCT) measurement data with reduced effects of motion are presented. One embodiment involves determining the amount of motion present during the collection of an OCT data set based on images of the eye collected at the same time as the OCT data, and recollecting select portions of the OCT data set when the amount of eye motion is determined to exceed a predetermined threshold. Another embodiment includes enabling or disabling a tracking feature based on the quality of the images available for tracking. Another embodiment includes reducing the effect of motion in the axial direction based on a comparison to a model of the eye constructed from OCT data. The method can also be used to reduce the presence of mirror image artifacts in an OCT image.

Abstract: The invention relates to an optical system for examining an eye by means of optical coherence tomography. The OCT system is designed in such a way that at least a first and a second state of the optical system can be selectively set by controlling the variable optical unit. In the first state, the OCT measurement beam has a measurement focus at an object distance from the objective, wherein the object distance has a value between 50 millimeters and 400 millimeters. In the second state, the measurement beam has defocusing at the same object distance, wherein the defocusing corresponds to a distance of a virtual or real focus from a position of the object distance that is greater than 100 millimeters.

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.

Abstract: Methods and apparatus for imaging multiple retinal structures and montaging of multiple retinal images are provided. The method involves cross-correlating images from different imaging channels to compensate for intra-frame distortion due to retinal movement during image acquisition, and conducting a second cross-correlation to filter out any motion artifacts in the images. The resultant images are combined to generate a composite image. The method also involves controlling light directed on the retina spatially and temporally.

Abstract: A modular lens adapter system or kit is provided for mobile anterior and posterior segment ophthalmoscopy. Equipped with various lens adapter modules, respective lenses and a mobile imaging device, a user is provided with tools for various mobile ophthalmoscopy imaging applications. Eye care practitioners can use their existing lenses to customize the modular lens adapter system in a cost-effective way, which allows for mobile and remote capture, viewing, and utilization of clinical images. The various modules are also adaptable to nearly any type of phone or tablet regardless of its dimensions or presence of a protective case. The invention also addresses the need for fewer, smaller, less expensive, and easier to use ophthalmic imaging equipment, which is further important in enabling a broad base of users.

Abstract: Systems and methods for imaging an eye are disclosed. The systems and methods may include at least one plenoptic camera. The systems and methods may include an illumination source with a plurality of lights.

Abstract: Lighting device (10) having a support (11), a plurality of emitting elements (12) adapted to emit light, fixed to the support (11) and each having an emission direction (A) radial to a predefined optical axis (B). The lighting device (10) is provided with a reflection surface (13) facing the emitting elements (12) and configured to reflect the light emitted in use by the latters in a direction parallel to the optical axis (B).

Abstract: Embodiments of the present invention relate to ultrasound (acoustic) data transmission systems, in particular data transmission over wide-band acoustic channels with frequency-dependant multi-path propagation. More specifically, embodiments of the invention involve increasing the bit rate in the acoustic channel by means of utilization of the entire ultrasound spectrum available for data transmission inside a human body.

Abstract: Systems, devices and methods for using environmental data to manage health care are disclosed. One aspect is an advanced patient management system. In various embodiments, the system includes at least one implantable medical device (IMD) to acquire at least one IMD parameter indicative of patient wellness, means to acquire at least one environmental parameter from at least one external source, and means to correlate the at least one parameter indicative of patient wellness and the at least one environmental parameter to assist with patient health care decisions. Other aspects and embodiments are provided herein.

Abstract: A photoacoustic wave measuring apparatus, having: a probe including a plurality of devices which detect an acoustic wave generated by irradiating light onto an object; and a signal processor which acquires information about the object on the basis of an acoustic wave received by the devices, wherein the light is irradiated onto the object from the probe side; the probe includes: bright-field devices having a view angle covering a bright-field illumination area, which is an area where the light is irradiated, on the probe-side surface of the object; and dark-field devices having a field of view which does not cover the bright-field illumination area; and the signal processor uses an acoustic wave received by the dark-field devices when acquiring information about the object on the basis of a acoustic wave received before a predetermined time period is elapsed since the irradiation of light onto the object.

Abstract: The invention provides methods and compositions for determining whether a subject containing a stent immobilized in a blood vessel has asymptomatic stent thrombosis or is at risk of developing clinically symptomatic stent thrombosis. In one approach, the method involves imaging a region of the blood vessel that contains the stent using a probe that contains a fluorochrome, for example, a near-infrared fluorochrome, and a targeting moiety that binds a molecular marker indicative of the presence of asymptomatic stent thrombosis or the development of symptomatic stent thrombosis. To the extent that the subject displays one or more such markers, the probe binds to the markers and increases the local concentration of the probe in the vicinity of the stent. The imaging method identifies those patients that display a higher density of such markers in the vicinity of the stent. As a result, those patients can be monitored for, and/or treated to prevent, symptomatic stent thrombosis.

Abstract: The present disclosure provides an OCT imaging system having a variety of advantages. In particular, the OCT system of the present disclosure may provide a more intuitive interface, more efficient usage of controls, and a greater ability to view OCT imaging data.

Abstract: A system for multimodal laser speckle imaging may include a first light source positioned to emit laser light toward a target, a second light source positioned to emit light toward the target, a camera positioned to receive light scattered from the target, and a processor.

Abstract: Interior scan and exterior photos are jointly visualized in medical imaging. One or more cameras are mounted to the internal medical scanner, allowing a photograph to be taken while or in temporal proximity to when the internal region of the patient is scanned. An image associating the exterior photographs with the interior region of the patient is presented to assist in diagnosis. Due to the spatial and temporal proximity, the image may be a visualization formed by combining the photograph and interior scan data.

Abstract: The present disclosure provides systems and methods for imaging based on the generation and use of mismatched coded excitation signals. Cross-correlation properties of the received signal reveal the location and/or timing and/or properties of the source. The use of mismatched signals enables spatial and/or temporal and/or functional encoding of the transmitted signals. In some embodiments, high-speed imaging may be performed by employing mismatched codes for spatial and/or temporal encoding, and by employing a subset of transducer elements as transmitters, and another subset of elements as receivers. Various example embodiments of different types of mismatched codes are provided, including codes that employ multiple frequency chirps, codes that employ concatenated multi-frequency binary phase-coded waveforms, and chirped binary phase-coded waveforms.

Abstract: Embodiments of the present disclosure relate to a system and method for determining a risk, onset, or presence of hypovolemia based on one or more features of a plethysmographic waveform during a patient breathing cycle. For example, a hypovolemic patient may exhibit characteristic changes in pulse amplitude or stroke volume during inhalation and exhalation relative to a healthy patient. Further, a trend or pattern of such features may be used to assess the patient's fluid condition.

Abstract: A blood pressure gauge for monitoring the blood pressure values of a patient in a darkened or low light environment. The blood pressure gauge is selectively illuminated when an internal air pressure within an attached blood pressure cuff is first detected or after it has reached a predetermined threshold value as determined by a pressure transducer in the blood pressure gauge. The blood pressure gauge is illuminated by a plurality of light emitting diodes or by plurality of components comprised of photoluminescent material. The blood pressure cuff is inflated by the actuation of a bulb attached to the blood pressure gauge. The bulb is actuated or squeezed against a stationary hand grip portion of the blood pressure gauge so as to provide a greater compressive force and deliver a larger volume of air to the blood pressure cuff.

Abstract: Vascular conditions are detected non-invasively in the human body using a collection of information from small local regions of the vasculature, or from a specific signature or “BrainPulse” that can be derived from a patient's heartbeat-induced cranium movements. An array of accelerometers or other sensors are engaged against the head of a patient and skull movements, preferably under 100 Hz, are recorded. Vibration signatures of vessel structures such as branches, aneurysms, stenosis, etc. using random, periodic, band limited or transient analysis provides a library for further processing. The signature library is used to localize the origin of the recognized vascular feature, and the localized feature is presented to the physician in a clinically relevant manner.

Abstract: A method of analyzing a complex rhythm disorder in a human heart includes accessing signals from a plurality of sensors disposed spatially in relation to the heart, where the signals are associated with activations of the heart, and identifying a region of the heart having an activation trail that is rotational or radially emanating, where the activation trail is indicative of the complex rhythm disorder and is based on activation times associated with the activations of the heart.

Abstract: Reflective surfaces for the apertures of PPG optical components in PPG systems is disclosed. In a PPG system or device, the addition of reflective surfaces around, under, or near the apertures of the optical components can enhance the amount of light received by the light detector. As a result, the measured PPG signal strength can be higher and more accurate compared to the same PPG device without reflective surfaces. The reflective surfaces can reflect and/or recycle light that is incident upon the reflective surfaces back into the skin for eventual capture of the light by the light detectors. In some examples, the reflective surfaces can be diffuse or specular reflectors and/or can be configured to selectively reflect one or more wavelengths of light. In some examples, the back crystal and/or component mounting plane of the PPG system can be made of the same material as the reflective surfaces.

Abstract: A medical pendant system, comprising: a movable component, an execution component and a bus (1); the movable component comprises a key control module (3); the key control module (3) comprises a braking system control key (K1, K4) and a pendant lifting/lowering control key (K2, K3); the execution component comprises an output control part (4), the output control part (4) being connected respectively with a bus power supply (5), a pendant motor (9) and a braking system (10); the movable component and the execution component are connected respectively to the bus (1); the bus (1) is used for transmitting power supply and also for transmitting instructions from the movable component to the execution component. In the vertical direction the medical pendant system can be adjusted steplessly without having to alter the lengths of the cables.

Abstract: A magnetic resonance method and system are provided for generating real-time motion-corrected perfusion images based on pulsed arterial spin labeling (PASL) with a readout sequence such as a 3D gradient and spin echo (GRASE) image data acquisition block. The real-time motion correction is achieved by using a volumetric 3D EPI navigator that is provided during an intrinsic delay in the PASL sequence, which corrects for motion prospectively and does not extend the image data acquisition time as compared to a similar non-motion-corrected imaging procedure.

Abstract: A plethysmograph variability processor inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. The processor derives plethysmograph values based upon selected plethysmograph features, determines variability values, and calculates a plethysmograph variability parameter. The variability values indicate the variability of the plethysmograph features. The plethysmograph variability parameter is representative of the variability values and provides a useful indication of various physiological conditions and the efficacy of treatment for those conditions.

Abstract: An ECG system measures and annotates the I-point of in an ECG waveform from harmonic waveforms. Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients. A discontinuity point is identified as the I-point of the ECG waveform from the comparison. The ECG waveform is displayed along with a marker at a location of the discontinuity point.

Abstract: An apparatus for generating ECG recordings and a method for using the same are disclosed. The apparatus includes a handheld device having four electrodes on an outer surface thereof, the handheld device having an extended configuration and a storage configuration. The apparatus also includes a controller configured to measure signals between the electrodes to provide signals that are used to generate an ECG recording selected from the group consisting of standard lead traces and precordial traces. When the handheld device is in the extended configuration and the first and second electrodes contact a first hand of a patient such that the first and second electrodes contact different locations on the first hand, the third electrode is in contact with a location on the patient's other hand and the fourth electrode contacts a point on the patient's body that depends on the particular trace being measured.

Abstract: Wearable devices are provided including electrical contacts to detect voltages or other biosignals when mounted to the skin of a wearer. The impedance between a pair of the electrical contacts can be detected and the device operated based on the detected impedance. The device can detect an electrocardiogram or other biopotentials using the electrical contacts if the detected impedance falls below a specified threshold. The device could indicate that the detected impedance is below the specified threshold, e.g., such that a wearer could contact one of the electrical contacts with a finger to allow detection of an electrocardiogram between the arms of the wearer. The device could indicate that the detected impedance remains greater than the specified threshold, e.g., such that a wearer could re-mount the wearable device to improve the electrical connection between the electrical contacts and the wearer's skin.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a system for mapping the electrical activity of the heart. The system may include a catheter shaft with a plurality of electrodes. The system may also include a processor. The processor may be capable of collecting a set of signals from at least one of the plurality of electrodes. The set of signals may be collected over a time period. The processor may also be capable of calculating at least one propagation vector from the set of signals, generating a data set from the at least one propagation vector, generating a statistical distribution of the data set and generating a visual representation of the statistical distribution.

Abstract: Brain-Machine Interface (BMI) systems or movement-assist systems may be utilized to aid users with paraplegia or tetraplegia in ambulation or other movement or in rehabilitation of motor function after brain injury or neurological disease, such as stroke, Parkinson's disease or cerebral palsy. The BMI may translate one or more neural signals into a movement type, a discrete movement or gesture or a series of movements, performed by an actuator. System and methods of decoding a locomotion-impaired and/or an upper-arm impaired subject's intent with the BMI may utilize non-invasive methods to provide the subject the ability to make the desired motion using an actuator or command a virtual avatar.

Abstract: A neurofeedback system for providing neurofeedback to at least one patient. The neurofeedback system includes: EEG head sensors; a central server to store treatment protocol algorithm(s) provided via the Internet; and a data collection module associated with a computer-based device. The data collection module: transmits the EEG brain activity to the central server via the Internet by way of the computer-based device; provides feedback to the patient; and receives a treatment protocol from the central server via the Internet by way of the computer-based device.

Abstract: A method and device to impart the ability to selectively quantify chemical/biochemical analytes occupying physiological fluids via an automated process that allow the precise and spatially-defined simultaneous deposition of a thin-film of polymer containing an immobilized biorecognition element dispersed therein. A tissue penetrating electrochemical sensor comprises at least one working electrode and at least one of a reference electrode and a counter electrode.

Abstract: System and method of using electromagnetic radiation signals to non-invasively test a glucose level in a subject. During operation, an incident beam of Terahertz waves is generated and projected onto the surface of the eyeball, which is naturally reflected by a tear layer. The reflected Terahertz waves are detected and characterized to determine the reflection characteristics of the tear layer, e.g., an axial ratio of reflection coefficients in two polarization orientations. Provided with the determined axial ratio and according to a predetermined correlation among axial ratio, tear glucose level and blood glucose level, the current blood glucose level in the subject can be derived and presented to a user.

Abstract: System and method of using electromagnetic radiation signals to non-invasively test a glucose level in a subject. During operation, an incident beam of Terahertz waves is generated and projected onto the surface of the eyeball, which is naturally reflected by a tear layer. The reflected Terahertz waves are detected and characterized to determine the reflection characteristics of the tear layer, e.g., an axial ratio of reflection coefficients in two polarization orientations. Provided with the determined axial ratio and according to a predetermined correlation among axial ratio, tear glucose level and blood glucose level, the current blood glucose level in the subject can be derived and presented to a user.

Abstract: The present invention relates to an impedance measuring device obtaining impedance of portions of an object corresponding to two sensing electrodes by detecting, through the two sensing electrodes, an electrical variation shown on the object as an electrical signal is applied. A detector amplifying each of signals detected through the two sensing electrodes and then differential-operating the amplified signals to generate a signal for obtaining impedance is subjected to a calibration process for adjusting the gain of the amplifiers to reduce in-phase noise added due to an imbalance between the sensing electrodes.

Abstract: Electrode sensor comprising an array of spaced apart individual contact elements (27?, 41), and an interface structure (30, 35) for forming contact between said contact elements and the skin; said interface structure comprising an interface layer of an essentially electrically insulating or poorly electrically conducting material (20?, 29, 37) defining a skin (31) contact surface on one side and an array contact surface on the other side of the interface layer, a first pattern of an electrically conducting material on the array contact surface, a second pattern of an electrically conducting material on the skin contact surface, and electrical pathways (21?, 39) connecting the first pattern with the second pattern; whereas, the first pattern comprises pattern elements, each individual contact element (27?, 41) comprises a contacting surface area large enough to cover several pattern elements of said first pattern when contacting the array contact surface of the interface structure, and by contacting distinct s

Abstract: A post processing system for electrical impedance tomography (EIT) images includes a processing device and a post processing device, and the post processing device is coupled to the processing device. The processing device is configured to generate a first EIT image through a solving method based on the measuring data. The measuring data is measured by an electrical impedance tomography instrument. The post processing device is configured to receive the first EIT image and post-process the first EIT image through a neural network algorithm to generate a second EIT image. The neural network algorithm is a feed forward neural network, a recurrent neural network, a convolutional neural network or a deep neural network, and an accuracy of the second electrical impedance tomography image is higher than an accuracy of the first electrical impedance tomography image.

Abstract: Computer-assisted structuring of medical examination data and/or one or more examination data records is disclosed. A method of at least one embodiment includes providing at least one medical examination data record, which includes patient-specific data described textually and/or symbolically and/or at least one image data record created with the aid of a radiological examination device; providing at least one body model image, which represents a body model matching the examination data; and registering the at least one examination data record with the body model, wherein at least one position in the body model is assigned to the examination data record; the position being made known for interaction by way of a user interface.