Patents Issued in October 9, 2018
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Patent number: 10092466Abstract: A shock-absorbent anti-tilt structure of an electric carrier coordinates with a steering system, which includes a steering axis and two sets of wheels. The shock-absorbent anti-tilt structure of an electric carrier includes a frame and an anti-tilt assembly. The frame includes a wheel axle, a first extension section pivotally connected to the wheel axle, a second extension section pivotally connected to the first extension section, and a bushing bridging the second extension section and the steering axis. The anti-tilt assembly includes two clamping members connected to the wheel axle and extending along the same direction as the first extension section, and two dampers respectively clamped by the clamping members and located closely to two sides of the first extension section. When the wheel axle receives a force and becomes unleveled with the ground, each of the dampers produces a reverse torque on the first extension section.Type: GrantFiled: May 17, 2017Date of Patent: October 9, 2018Assignee: KUIANDA COMPANY LIMITEDInventor: Mao-Chiang Chen
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Patent number: 10092467Abstract: A seating furniture chassis having a height-adjustable seat surface, a drive means, a shaft, a height-adjustment mechanism and a threaded rod, wherein the drive means is coupled to the shaft and is designed to transmit a torque to the threaded rod by means of the shaft, and wherein the height-adjustment mechanism is coupled to the threaded rod and to the seat surface such that a rotation of the threaded rod is converted into a height adjustment of the seat surface by means of the height-adjustment mechanism, characterized in that a longitudinal axis of the shaft is not arranged parallel to a longitudinal axis of the threaded rod.Type: GrantFiled: January 6, 2016Date of Patent: October 9, 2018Assignee: Innotec Motion GmbHInventor: Michael Mackert
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Patent number: 10092468Abstract: To provide a nursing bed capable of preventing bedsores of a care receiver while minimizing a burden on the body of the care receiver when changing posture. A nursing bed with a longitudinal dimension and a width dimension has an upper surface forming member which forms a bed upper surface on which a care receiver lies and a driving mechanism configured to move at least a portion of the upper surface forming member. The bed upper surface includes a curved surface which is curved downwardly in the width direction.Type: GrantFiled: December 24, 2013Date of Patent: October 9, 2018Assignee: KAWASAKI JUKOGYO KABUSHIKI KAISHAInventor: Yasuhiko Hashimoto
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Patent number: 10092469Abstract: A rotational transfer platform system which aids in transferring an immobile individual from one location to another. The rotational transfer platform system generally includes a platform which is rotatably connected to a base which is adapted to rest on the ground. A walker frame extends from the upper surface of the platform to aid in securing any individual standing on the platform. The walker frame may be adapted to transition between an expanded state for use and a collapsed state for transport or storage. A locking member may be utilized to selectively lock rotation of the platform with respect to the base in one of a plurality of different radial positions to ease with transferring an individual from one location to another.Type: GrantFiled: June 12, 2017Date of Patent: October 9, 2018Inventor: Torrance D. Lillevold
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Patent number: 10092470Abstract: A combination patient-transfer and intraoperative heater device has a top and bottom chamber separated by a barrier. The patient rests on the top chamber, which has a plurality of apertures for discharge of temperature-controlled filtered heated or cooled air at a regulated pressure for patient comfort and mitigation of infection. Heated or cooled filtered air is delivered to the area surrounding the patient, maintaining body temperature during anaesthesia. The bottom chamber has a plurality of apertures. When air pressure is low or off, the bottom chamber is flat and un-inflated. When air pressure is increased, air enters the bottom chamber and the apertures emit air, creating an air cushion facilitating lateral movement of the lifter device. The device performs two functions that now require separate devices and air blowers, it saves space and reduces both costs and complexity in the operating room while mitigating risk of infection.Type: GrantFiled: February 18, 2014Date of Patent: October 9, 2018Inventor: Randall J. Lewis
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Patent number: 10092471Abstract: The present invention provides systems, methods, and apparatus for applying a hyperoxic therapy delivery system to a patient; administering hyperoxic gas to the patient according to an oxygen dose-response model; and adjusting the administration of the hyperoxic gas to the patient based upon monitored parameters related to a condition of the patient. Numerous additional features are disclosed.Type: GrantFiled: September 3, 2014Date of Patent: October 9, 2018Assignee: MICROBARIC OXYGEN SYSTEMS, LLCInventors: Michael W. Allen, Russell E. Peterson, Glenn Butler
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Patent number: 10092472Abstract: In nurse call systems where communication between a plurality of slave units and a plurality of extension terminals is possible, a nurse call controller serving the slave units and a private branch exchange serving the mobile terminals have been connected to each other through a nurse call adaptor; thus, there is a need for one such nurse call system that does not require a nurse call adaptor. Provided is an interface unit which is connected to a nurse call controller through a plurality of ISND basic interfaces, connected to a private branch exchange through an ISDN primary rate interface, and performs interface conversion therebetween.Type: GrantFiled: October 22, 2015Date of Patent: October 9, 2018Assignees: NEC Platforms, Ltd., NIPPON TELEGRAPH AND TELEPHONE EAST CORPORATION, NIPPON TELEGRAPH AND TELEPHONE WEST CORPORATIONInventors: Takuya Omi, Shigeru Maruyama, Kou Nogami, Rintarou Ashida, Ken Utsuki, Norio Murakami
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Patent number: 10092473Abstract: A dental chair is provided including a chair assembly comprising a backrest, a seat, and a base; and at least one set of utility ports disposed on the chair, adjacent to the seat, each port having a quick release fitting for receiving a flexible conduit connected to a hand piece.Type: GrantFiled: September 21, 2016Date of Patent: October 9, 2018Assignee: Bio-Dent, Inc.Inventor: Sargon Lazarof
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Patent number: 10092474Abstract: A supporting frame and a motion assistance apparatus including the same may be provided. In particular, the supporting frame including a first frame including a hinge connecting portion, a second frame configured to slidingly move with respect to the first frame, and an assistance force sensing portion on at least one of the first frame and the second frame may be provided.Type: GrantFiled: January 14, 2015Date of Patent: October 9, 2018Assignee: Samsung Electronics Co., Ltd.Inventors: Youn Baek Lee, Byungjune Choi, Hyun Do Choi, Jeonghun Kim, Se-Gon Roh, Minhyung Lee, Jongwon Lee
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Patent number: 10092475Abstract: A combination crutch and knee walker device converts between a rolling knee walker configuration and a crutch configuration through a single folding or expanding articulation that requires no tools or skillset. The device includes a first support bar that forms the primary lever of support. A second support bar pivotally joins the first support bar at a hinged junction, generally three-quarters down from the top of the first support bar. The support bars fold and expand about the hinged junction to convert between crutch and knee walker. A panel hingedly joins at the hinged junction serving as a supportive platform for an upper body, such as the arm or the knee, depending on the crutch or knee walker configuration. Further, the mobility function, such as rolling rollers, will restrict or free rotation depending on the selected configuration of the device.Type: GrantFiled: April 10, 2017Date of Patent: October 9, 2018Inventor: Philip Smith
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Patent number: 10092476Abstract: A device for providing hands-optional mobility to a visually impaired toddler is disclosed. The device has a frame with vertical rods that connect to a toddler's body with a fastener. Curved surfaces at the distal ends of the rods slide along the floor and transmit tactile sensations to the toddler. Advantageously, the vertical rods are sufficiently flexible that the toddler cannot utilize the rods as walking aids.Type: GrantFiled: September 29, 2016Date of Patent: October 9, 2018Assignee: Research Foundation of the City University of New YorkInventor: Grace Ambrose-Zaken
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Patent number: 10092477Abstract: Provided are systems (100) for control of or determining the effectiveness of a neck suction device using one or more secondary metrics. A sensor device (101) may be used to measure or determine one or more secondary metrics relating to the neck of a patient in response to the application of suction to the neck of the patient proximal to the hyoid bone of the patient by a neck suction device. A processing device (107) may then determine whether to adjust the suction intensity in response to the measured/determined metrics. The metrics may also be use do determine whether neck suction is likely to be effective for a specific patient.Type: GrantFiled: May 17, 2013Date of Patent: October 9, 2018Assignee: KONINKLIJKE PHILIPS N.V.Inventor: Jonathan Sayer Grashow
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Patent number: 10092478Abstract: A complexion and neck treatment band (CNTB) for a user, by which compound mechanical stimulation is applied to the skin of the face and surrounding skin patches. The band fits around the head of the user, forming a tight fit with the skin of the complexion and possibly neck. The user can apply generalized stretch, and using special stretch lobes also apply localized stretch.Type: GrantFiled: September 6, 2017Date of Patent: October 9, 2018Inventor: Noah Amit
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Patent number: 10092479Abstract: A massage therapy device having a roller and detachable thermal cover is disclosed. The roller has a series of unique ridges that optimize the application of therapeutic pressure to portions of a user's body. The thermal cover contains thermal retention material that can be heated or cooled. When the thermal cover is detachably connected to the roller, thermal therapy can be applied to muscle and other tissue in conjunction with the pressure therapy applied with the ridges of the roller. The configuration, temperature, and pressure application angle of the device can be varied to maximize the versatility of the device and provide individualized treatment.Type: GrantFiled: December 10, 2013Date of Patent: October 9, 2018Assignee: KOREEXTREME LLCInventors: Shawn Babiarz, Matthew Gelber
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Patent number: 10092480Abstract: The present invention is a touchscreen-based control system for massage chairs that includes a touchscreen device. In another aspect, the present invention is a massage chair controlled by a touchscreen-based control system that includes a touchscreen-based control system. In a further aspect, the present invention is a massage chair controlled by a touchscreen-based control system that includes a touchscreen-based control system and at least one health monitoring device or system.Type: GrantFiled: February 26, 2015Date of Patent: October 9, 2018Assignee: Luraco, Inc.Inventors: Kevin Le, Thanh Le, Manthan Sheth
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Patent number: 10092481Abstract: Increasing blood circulation, lowering intracranial pressure, and increasing cerebral perfusion pressure during the administration of cardiopulmonary resuscitation by gravity-assist due to elevation of one or both of the torso and head of an individual.Type: GrantFiled: April 2, 2015Date of Patent: October 9, 2018Inventor: Keith G. Lurie
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Patent number: 10092482Abstract: Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamides, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.Type: GrantFiled: June 3, 2008Date of Patent: October 9, 2018Assignee: Colgate-Palmolive CompanyInventors: Prithwiraj Maitra, Lynette Zaidel, Suman K. Chopra, Guisheng Pan, Michael Prencipe, Sayed Ibrahim
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Patent number: 10092483Abstract: An array of at least two commonly-branded absorbent articles, such as wipes products. The array includes a first wipes product and a second wipes product. Each wipes product may appeal to a different type of consumer, such as a light experience seeking consumer and a heavy experience seeking consumer. The first wipes product may include a first supply of wipes formed from a first substrate. The first supply of wipes is moistened with a first functional lotion composition including a first fragrance accord and a first lotion formula. The second wipes product may include a second supply of wipes formed from a second substrate. The second supply of wipes is moistened with a second functional lotion composition including a second fragrance accord and a second lotion formula. The second fragrance accord is different from the first fragrance accord, and the second lotion formula is different from the first lotion formula.Type: GrantFiled: May 20, 2016Date of Patent: October 9, 2018Assignee: The Procter & Gamble CompanyInventors: Alizha V. Smith, Randall Glenn Marsh, Oliver Edwin Clarke Mason
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Patent number: 10092484Abstract: A cosmetic composition is disclosed comprising particle active and cosmetically acceptable carrier comprising hydrophobic material, wherein the hydrophobic material comprises less than 15% liquid oil by weight of the composition. The particle active comprises (i) water-insoluble shell component comprising inorganic material and having a refractive index of from 1.3 to 1.8; and (ii) core component comprising volatile liquid and having a refractive index of at least 1.2.Type: GrantFiled: September 30, 2014Date of Patent: October 9, 2018Assignee: Conopco, Inc.Inventors: Florian Hudelist, Yajuan Li, Zhaoting Liu, Sheng Meng, Qiang Qiu, Lin Wang, Xiaoli Wang, Chunwei Wu
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Patent number: 10092485Abstract: The present invention relates to benefit agent containing delivery particles, compositions comprising said particles, and processes for making and using the aforementioned particles and compositions. When employed in compositions, for example, cleaning or fabric care compositions, such particles increase the efficiency of benefit agent delivery, thereby allowing reduced amounts of benefit agents to be employed. In addition to allowing the amount of benefit agent to be reduced, such particles allow a broad range of benefit agents to be employed.Type: GrantFiled: October 2, 2014Date of Patent: October 9, 2018Inventors: Johan Smets, An Pintens, Laura Orlandini, Dorothy Peggy Sands
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Patent number: 10092486Abstract: Poiyurea or polyurethane capsule compositions. A subset of these compositions contain a plurality of capsules and a capsule formation aid, in which each of the capsules contains a poiyurea or polyurethane wall and an oil core; the poiyurea or polyurethane wall is formed of a reaction product of a polyisocyanate and a cross-linking agent in the presence of the capsule formation aid; and the oil core contains an active material. The polyisocyante, cross-linking agent, and capsule formation aids are described herein. Also disclosed are methods of preparing poiyurea and polyurethane capsule compositions, as well as consumer products containing one of these compositions.Type: GrantFiled: August 15, 2014Date of Patent: October 9, 2018Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC.Inventors: Yabin Lei, Li Xu, Lewis Michael Popplewell
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Patent number: 10092487Abstract: Zinc oxide compositions as well as techniques for plasmonic enhancement of absorption in sunscreen applications are provided herein. A method includes selecting one or more metal particles to be used in conjunction with one or more zinc oxide particles in a sunscreen composition, wherein said selecting is based on the plasmon resonance frequency associated with each of the metal particles; and embedding the one or more selected metal particles into each of the one or more zinc oxide particles.Type: GrantFiled: April 29, 2016Date of Patent: October 9, 2018Assignee: International Business Machines CorporationInventors: Talia S. Gershon, Yun Seog Lee, Ning Li, Devendra Sadana, Teodor K. Todorov
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Patent number: 10092488Abstract: A system and method which enables application of a material to teeth (and gums), which material remains in contact with, and adheres to, said teeth and gums for a period long enough to neutralize acids in dental plaque biofilm, inhibit plaque from adhering to teeth and gums, encourage removal of dental plaque, and form a barrier between the teeth and gums and the oral environment.Type: GrantFiled: November 18, 2016Date of Patent: October 9, 2018Inventor: Janet M. Wehrli
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Patent number: 10092489Abstract: Consumer product compositions comprising hydrophobically modified urea ethers.Type: GrantFiled: March 13, 2017Date of Patent: October 9, 2018Assignee: The Procter & Gamble CompanyInventors: Susana Fernandez-Prieto, Marc Dolatkhani, Wim Michel De Borggraeve, Monissa Cuebillas Paderes
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Patent number: 10092490Abstract: The invention concerns a method for straightening keratinous fibers including: (i) a step of applying on the keratinous fibers a hair straightening composition containing at least one cyclic or linear amide, (ii) a step of increasing the temperature of the keratinous fibers, using heating means, to a temperature ranging between 110 and 250° C.Type: GrantFiled: May 23, 2007Date of Patent: October 9, 2018Assignee: L'OrealInventors: Gérard Malle, Anne-Claude Dublanchet, Philippe Barbarat
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Patent number: 10092491Abstract: A system for enhancing skin renewal is provided, including a first phase having an anhydrous solvent, a hydroxy acid, and urea, and a second phase having a neutralizing agent and optional abrasive. A composition is provided, wherein the first phase includes glycerin, lactic acid, and urea, and wherein the second phase includes a neutralizing agent and optional abrasive. A process of increasing the rate of skin cell renewal in a subject is provided, which includes topically applying systems or compositions of the disclosure, such that dead skin cells are removed and replaced with new corneocytes, thereby increasing the rate of skin cell renewal.Type: GrantFiled: March 21, 2016Date of Patent: October 9, 2018Inventor: John E. Kulesza
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Patent number: 10092492Abstract: The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: an aqueous phase, spiculisporic acid, at least one non-sulfate and non-sulfonate surfactant, and at least one base, wherein the ratio R1 of number of moles of base over the number of moles of spiculisporic acid is strictly greater than 1.Type: GrantFiled: November 7, 2014Date of Patent: October 9, 2018Assignee: L'OREALInventors: Isabelle Terrisse, Caroline Sirichandra
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Patent number: 10092493Abstract: The present invention relates to an anti-aging composition for external use on skin, and more particularly, to an anti-aging composition for external use on skin comprising at least one of catechins and flavonols as an active ingredient to inhibit decomposition and promote generation or protection at the dermis-epidermis junction.Type: GrantFiled: March 2, 2016Date of Patent: October 9, 2018Assignee: AMOREPACIFIC CORPORATIONInventors: Jeong Ki Kim, Hyun Jung Shin, Su Nam Kim, Byeong Gon Lee, Ih Seop Chang
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Patent number: 10092494Abstract: Sunscreen compositions, products and methods that include at least one UVA sunscreen active agent, at least one UVB sunscreen active agent, and one or more water insoluble film forming polymers. The compositions, products and methods may further include one or more active or inactive cosmetic ingredients. The water insoluble film forming polymers synergistically affect the UVA and UVB sunscreen active agents, in particularly the UVA sunscreen active agents by significantly enhancing the water resistance of the UVA sunscreen active agents after water exposure as determined by the SPF and UVAPF values measured before and after water exposure.Type: GrantFiled: September 13, 2016Date of Patent: October 9, 2018Assignee: Edgewell Personal Care Brands, LLC.Inventors: James SaNogueira, Glenn Wiener, Tao Zheng
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Patent number: 10092495Abstract: The invention concerns a use of C7 sugars and derivatives of formula (I), called avocado perseose, which have, inter alia, a protective activity to epidermal skin cells. These C7 sugars and derivatives are capable of maintaining the expression of markers of adult stem cells, in particular basal stem cells. Avocado perseose can also be used for preventing the deleterious effects of environmental damage. Avocado perseose has a beneficial effect on the conservation of the potential of epidermal stem cells and thus helps maintain skin homeostasis.Type: GrantFiled: February 11, 2014Date of Patent: October 9, 2018Assignee: LABORATOIRE EXPANSCIENCEInventors: Philippe Msika, Caroline Baudouin
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Patent number: 10092496Abstract: A solid base material for skin external application has a breaking strength high enough to be used for a stick-shaped base material and the like. A solid base material for skin external application has: a surfactant; water; and a lipid peptide compound including at least one of compounds of Formula (1) and the analogous thereof or pharmaceutically usable salts of the compound: wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom, or a C1-4 alkyl group that may have a C1 or C2 branched chain; R3 is a —(CH2)n—X group, where n is a number from 1 to 4, and X is amino group, guanidino group, —CONH2 group, or a 5-membered or 6-membered ring that may have 1 to 3 nitrogen atoms or a condensed heterocycle composed of 5-membered and 6-membered rings that may have 1 to 3 nitrogen atoms.Type: GrantFiled: December 25, 2014Date of Patent: October 9, 2018Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Takayuki Imoto, Tsubasa Kashino
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Patent number: 10092497Abstract: An agent for lightening keratin fibers, which, with regard to its weight, includes 20 to 75 wt. % of oil(s), 0.05 to 5 wt. % of polymer(s) from the group of copolymers of ethylene/propylene/styrene and/or copolymers of butylene/ethylene/styrene, and/or copolymers of butylene/propylene/styrene, and 1 to 70 wt. % of peroxydisulfate(s), wherein the fibers contain 1 to 44 wt. % of potassium peroxydisulfate and 0 to <5 wt. % of sodium peroxydisulfate, and 0 to <5 wt. % of ammonium peroxydisulfate. The agent has increased storage stability, whereby not only the physical stability (settling, phase separation) but also the chemical stability (decomposition of the peroxide salts) is improved.Type: GrantFiled: February 17, 2016Date of Patent: October 9, 2018Assignee: Henkel AG & Co. KGaAInventors: Burkhard Mueller, Udo Erkens
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Patent number: 10092498Abstract: The present invention relates to a cosmetic comprising an acrylonitrile-butadiene rubber (NBR) as a carrier of a cosmetic composition and, specifically, to a cosmetic comprising a foam carrier and a cosmetic composition loaded on the foam carrier, wherein the foam carrier contains an NBR, includes pores with an average size of 200-900 ?m, and has a thickness of 1-50 mm, and wherein the cosmetic composition has a viscosity of 2,000-60,000 cps. The present invention has excellent filling ability, loading ability, and discharging ability with respect to the liquid-phase cosmetic composition, and thus facilitates carrying a liquid-phase cosmetic composition with low viscosity to high viscosity.Type: GrantFiled: April 10, 2015Date of Patent: October 9, 2018Assignee: AMOREPACIFIC CORPORATIONInventors: Jung Sun Choi, Kyung Ho Choi
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Patent number: 10092499Abstract: The present invention relates to oral and dental care and cleaning agents comprising an aqueous dispersion of a phosphate-containing and/or phosphonate-containing polyurethane polymer and anionic surfactant(s), to tooth cleaning methods using these agents, and to the use of oral and dental care and cleaning agents comprising an aqueous dispersion of a phosphate-containing and/or phosphonate-containing polyurethane polymer and anionic surfactant(s) to reduce the restaining of teeth and/or to reduce biofilm development on dental surfaces and/or to reduce the adhesion of bacteria to dental surfaces and/or to extend the antibacterial action of antibacterial substances.Type: GrantFiled: December 13, 2016Date of Patent: October 9, 2018Assignee: Henkel AG & Co. KGaAInventors: Kristin Miehlich, Daniela Arians, Andreas Taden, Detlef Buisker
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Patent number: 10092500Abstract: The application relates to oral care compositions comprising substantive polyesteramides formed from polyols, polycarboxylic acids (or esters, anhydrides or halides thereof) and arginine. The formed polyesteramides are active in biofilm inhibition, biofilm dissolution and retarding or preventing acid production from oral bacteria.Type: GrantFiled: April 7, 2015Date of Patent: October 9, 2018Assignee: BASF SEInventors: Ted Deisenroth, Glen Thomas Cunkle, Lauren Junker, Michael Kuepfert, Paul Odorisio, Steven N. Saunders, Vishal Ramnarine, Neethu Abraham
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Temporary changing the color of hair using pigments, alcohols and specific polyalkoxylated silicones
Patent number: 10092501Abstract: Agents for temporarily changing the color of keratinous fibers, in particular human hair, include in an aqueous cosmetic carrier—relative to the total weight of the agent—(a) at least 20 wt % one or more aliphatic and/or aromatic alcohols having 2 to 8 C atoms, (b) at least one color pigment and (c) at least one non-ionic polyalkoxylated silicone, wherein the total amount of the fatty substances (d) included in the agent is at a value below 2.5 wt %.Type: GrantFiled: April 20, 2017Date of Patent: October 9, 2018Assignee: Henkel AG & Co. KGaAInventors: Konstantin Goutsis, Gabriele Weser -
Patent number: 10092502Abstract: The present invention relates to a cosmetic agent for dyeing, in particular for lightening keratin fibers, in particular human hair, including at least one specific aminated silicone polymer and at least one oxidation dye intermediate and/or one direct dye, wherein the use of the at least one aminated silicone polymer leads to improved care of the keratin fibers with improved hair lightening performance. The invention further relates to a corresponding packaging unit (kit of parts) and to a method for dyeing, in particular lightening, of keratin fibers. Lastly, the invention relates to the use of the cosmetic agent according to the invention and the use of a packaging unit for producing an oxidative hair lightener for care of keratin fibers with improved lightening performance.Type: GrantFiled: March 9, 2017Date of Patent: October 9, 2018Assignee: Henkel AG & Co. KGaAInventors: Sylvia Kerl, Susanne Bietz
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Patent number: 10092504Abstract: The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring aged or damaged skin to a healthy appearance. In preferred embodiments, the methods and agents comprise active extracts produced from fish eggs. The invention further provides processes for making active fish egg extracts.Type: GrantFiled: November 4, 2016Date of Patent: October 9, 2018Assignee: REGENICS ASInventors: Runhild Gammelsaeter, Jan Remmereit
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Patent number: 10092505Abstract: The present invention provides an oral film-form base which has a rapid dissolution profile in the mouth and sufficient film strength, and gives an improved taking property by foaming in the mouth. The oral film-form base includes an edible polymer soluble both in water and in an organic solvent having a solubility parameter of 9.7 or higher, a foaming agent, and an auxiliary foaming agent, wherein the foaming agent is foamable in the presence of water, and the foaming agent and the auxiliary foaming agent each are insoluble in the organic solvent, have an average particle size of 0.1 to 60 ?m, and are included in particle states.Type: GrantFiled: January 9, 2013Date of Patent: October 9, 2018Assignee: NITTO DENKO CORPORATIONInventors: Daisuke Asari, Mitsuhiko Hori, Takuya Shishido
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Patent number: 10092506Abstract: The present invention relates to a therapeutic agent formulation in the form of a nano-emulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises further to the therapeutic agent, at least one amphiphilic lipid and at least one solubilizing lipid, and in which the aqueous phase comprises at least one polyalkoxylated cosurfactant. The invention also relates to a preparation method and use of this formulation.Type: GrantFiled: August 14, 2009Date of Patent: October 9, 2018Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Veronique Mourier-Robert, Jerome Bibette, Mathieu Goutayer, Fabrice Navarro y Garcia, Isabelle Texier-Nogues
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Patent number: 10092507Abstract: The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.Type: GrantFiled: June 6, 2015Date of Patent: October 9, 2018Assignee: NanoVault Medical LLCInventors: Willard W. Hennemann, Bryan L. Steelman, Thomas J. Webster
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Patent number: 10092508Abstract: Implantable devices including a biocompatible matrix configured for long term location in adipose tissue and a biologically active agent that can be carried by the matrix and delivered to the adipose tissue following implant therein. The biologically active agent can include a modulator or a precursor thereof that can directly or indirectly modify the gene expression of adipose cells, e.g., adipocytes, and thereby modify the presence or quantity of one or more expression products of the adipose tissue that may act locally on distant from the implant site in an endocrine fashion. Modulators can include small molecules (e.g., resveratrol), polynucleotides (e.g., RNAi), or polypeptides (e.g., antibodies or functional fragments thereof).Type: GrantFiled: June 27, 2017Date of Patent: October 9, 2018Assignee: University of South CarolinaInventors: Robert Gower, Michael Hendley
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Patent number: 10092509Abstract: Hypotonic microbicidal compositions including an antimicrobial, such as an antiviral compound, and a pharmaceutically acceptable carrier in a solution formulation having hypotonic osmolarity have been developed for administration rectally to the gastrointestinal mucosa. In a preferred embodiment for use in preventing or decreasing HIV infection, the microbiocidal is tenofovir, or a prodrug or derivative thereof. The formulations may include additional agents such as surfactants to enhance cleansing, buffers, or preservatives. Polymers may be included for osmolarity as well as comfort.Type: GrantFiled: August 27, 2015Date of Patent: October 9, 2018Assignee: The Johns Hopkins UniversityInventors: Katharina Maisel, Craig W. Hendrix, Laura Ensign, Edward Fuchs, Richard Cone, Justin Hanes
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Patent number: 10092510Abstract: The invention relates to a method of inducing emesis in animals, particularly companion animals such as dogs and cats, in situations where vomiting is desired. The method comprises administering an eye drop composition comprising a selective D2 family dopamine agonist as an active ingredient to the eye of the animal to induce emesis. The method and the composition are useful in situations involving ingestion of a potentially toxic substance or foreign body by the animal.Type: GrantFiled: September 29, 2014Date of Patent: October 9, 2018Assignee: ORION CORPORATIONInventors: Jouko Levijoki, Lasse Saloranta, Johanna Kokkonen
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Patent number: 10092511Abstract: The invention relates to a pharmaceutical composition comprising a plurality of controlled-release coated microparticles each comprising a floating core, on the surface of which is deposited a layer containing at least one active principle, said layer being covered with a controlled-release coating, characterized by the fact that said floating core is composed of cellulose acetate phthalate and has an apparent density of less than or equal to 0.6 g/mL and said coated microparticles have a density of less than or equal to 0.7 g/mL.Type: GrantFiled: July 1, 2016Date of Patent: October 9, 2018Assignee: FLAMEL IRELAND LIMITEDInventors: Catherine Castan, Philippe Caisse
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Patent number: 10092512Abstract: The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.Type: GrantFiled: May 12, 2010Date of Patent: October 9, 2018Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Keith P. Johnston, Joshua Engstrom, Jasmine Rowe, Alan B. Watts, Robert O. Williams, III
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Patent number: 10092513Abstract: The application relates to an aqueous pharmaceutical formulation for use in the treatment of Type I or Type II Diabetes Mellitus, wherein the treatment reduces the risk of nocturnal hypoglycemia, said formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine, with the proviso that the concentration of said formulation is not 684 U/mL of insulin glargine.Type: GrantFiled: April 1, 2014Date of Patent: October 9, 2018Assignee: SANOFIInventors: Isabel Muhlen-Bartmer, Monika Ziemen
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Patent number: 10092514Abstract: The present invention aims to provide an eye drop for treating macular edema. The present invention provides an eye drop for treating macular edema, which contains difluprednate as an active ingredient. The eye drop can afford effects such as improvement of visual acuity and decreased foveal retinal thickness in macular edema.Type: GrantFiled: January 10, 2018Date of Patent: October 9, 2018Assignee: YAMAGATA UNIVERSITYInventors: Hidetoshi Yamashita, Teiko Yamamoto, Sakiko Goto, Sachi Abe, Eriko Kirii, Atsushi Okumura
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Patent number: 10092515Abstract: The present invention provides an intravenous liposomal formulation of a low dose polymyxin B or a pharmaceutical composition thereof. The present invention also provides methods utilizing the intravenous liposomal formulation or its pharmaceutical composition for increasing the therapeutic efficacy during treatment of a bacterial infection in a subject, for decreasing exposure of renal tissue to the polymyxin B during a course of polymyxin B treatment and for lowering exposure to polymyxin B in renal tissues in a subject receiving polymyxin B treatment.Type: GrantFiled: November 20, 2017Date of Patent: October 9, 2018Assignee: University of Houston SystemInventors: Vincent Tam, Diana Chow, Jie Gohlke
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Patent number: 10092516Abstract: The invention broadly comprises a chemical composition including a plurality of cholesteryl esters arranged to form a vesicle. In several embodiments, all of the plurality of cholesteryl esters have a same molecular length, which in some embodiments provides a vesicle having a generally smooth outer surface, while in other embodiments, a portion of the plurality of cholesteryl esters have different molecular lengths, which in some embodiments provides a vesicle having a generally irregular outer surface. In yet further embodiments, a shape of the vesicle is selected from the group consisting of spherical, oval, disc-like, tubular and polyhedral shapes, and in yet other embodiments, a wall of the vesicle is selected from the group consisting of a monolayer and a bilayer. In still further embodiments, the chemical composition further includes a polyethylene glycol coat of mixed polymer size.Type: GrantFiled: June 17, 2015Date of Patent: October 9, 2018Assignee: THERASYN SENSORS, INC.Inventor: Mary P. McCourt