Abstract: A sterilization system is configured to emit energy, such as UV radiation, for sterilizing a surface, such as a door handle, faucet handle, elevator button, or other target surfaces known in the art. The sterilization system is configured to operate automatically in response to detection of a user's hand interfacing with the handle. After a user releases a handle, the sterilization system is actuated to sanitize the handle for subsequent users.

Abstract: A medical accessory holder (10) is provided for use during processing of medical equipment. The holder (10) comprises a tray portion (11), retaining means (16, 17) associated with the tray portion (11), and securing means (13) provided on the tray portion (11). The retaining means (16, 17) are adapted to engage with a medical accessory (20) such that, once engaged, the medical accessory (20) cannot be disengaged without breaking the medical accessory holder (10), thereby rendering the holder (10) suitable only for single use. The securing means (13) enable the holder (10) to be secured to an article of medical equipment with which the medical accessory (20) is associated, during processing thereof.

Abstract: A device for dispersing foul gaseous effluent emissions released diffusely by sources located close to the ground, in particular by wastewater treatment ponds (10, 11, 12), includes: at least two auxiliary air or gas injectors (5a1, 5b1; 5a2, 5b2; 5a3, 5b3) oriented upwards and installed in opposing zones on the periphery of each foul gaseous effluent source, such as to disperse the gaseous effluents; separate supply elements (8.1, 13a1, 13b1; 8.2, 13a2, 13b2; 8.3, 13a3, 13b3) for the injectors; and wind-direction-sensitive control elements for ensuring that at least the injector(s) best located to disperse and/or lift the gaseous effluent plume are supplied.

Abstract: An air filtration media for use with a heating ventilation and air condition (HVAC) system is provided. The filtration media comprises an air filter media layer having a first and second side, a PCO media layer having a first and second side, and a barrier layer positioned between the second side of the air filter media layer and the first side of the PCO media layer. The air filter media layer, barrier layer, and PCO layer are pleated together and enclosed within a frame for placement adjacent a light source within a plenum of the HVAC system.

Abstract: A plurality of fibers or one-dimensional, two-dimensional, or three-dimensional fibrous structures are provided, having fibers from a first raw fiber material. The first raw fiber material contains unsubstituted or partially substituted polyvinyl alcohol and/or unsubstituted or partially substituted polyvinyl alcohol copolymer. The fibers can be crosslinked by tempering the fibers or fibrous structures, with the result that the fibers or the fibrous structure are configured to be gel, in particular hydrogel, fibers or fibrous structures and have excellent stability.

Abstract: An absorbent structure including a dryness layer laminate is disclosed, with the structure suitable for use in disposable absorbent products such as for infant or incontinence care. The dryness layer laminate is positioned adjacent an associated absorbent core, between the absorbent core and the wearer, for enhancing surface dryness and comfort for the wearer. The dryness layer laminate comprises adhesive fibers or filaments, and particulate superabsorbent, and is configured to permit liquid to pass through the laminate to the associated absorbent core, while acting to remove liquid from the surface of the absorbent structure positioned adjacent to the wearer.

Abstract: A prosthesis for a synovial joint arthroplasty within a human body is provided.

Abstract: A biohybrid scaffold is provided that is useful in clinical applications for abdominal wall reconstruction, pelvic floor repair, breast reconstruction, as well as other soft tissue repairs. Methods of making and using the biohybrid scaffold are provided.

Abstract: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.

Abstract: A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.

Abstract: Vascular scaffolds and methods of fabricating the same are disclosed for tissue engineering of vascular constructs. By combining electrospun matrices with cell sheet technologies, vascular constructs with more mature cell layers can be obtained for reconstruction of blood vessels, heart valves and the like. A engineered smooth muscle cell sheet, wrapped around an electrospun vascular scaffold, is able to provide a mature SMC layer that expresses strong cell-to-cell junction markers and contractile proteins. In addition, preconditioning of the cell sheet covered vascular scaffold maintained cell viability and infiltration into the scaffold.

Abstract: The present invention provides metal medical devices which are provided with sliding properties (lubricity), low protein adsorption properties and low cell adsorption properties and further in which these properties are prevented from deteriorating. The present invention relates to a metal medical device having a surface at least partially treated with a copolymer C of a polymerizable silane compound A and a polymerizable compound B that contains a functional group.

Abstract: A fluid drainage device, for use in a closed wound drainage system, which includes a fluid-receiving volume having a bore, a piston in sealing contact with the bore, a prop extending from the piston and which is connected to an energy storage device, wherein the piston can be user-actuated between a first position, whereby energy is stored in the energy storage device, to a second position, whereby energy is released from the energy storage device, to increase the size and reduce the pressure of the volume, allowing fluid to flow from a conduit into the volume.

Abstract: A bodily fluid collection system includes a reduced pressure treatment unit for providing reduced pressure to a fluid collection system through a canister having a container with an inlet adapted to be fluidly coupled to the fluid collection system, an outlet adapted to be connected to a source of reduced pressure, and an absorptive lamination disposed within the container. The absorptive lamination may be formed from a plurality of absorptive layers and wicking layers interleaved between the absorptive layers that collectively manifold bodily fluids from a tissue site into and throughout the absorptive lamination to trap and collect the bodily fluids. The container expands as the absorptive lamination swells with the bodily fluid being collected.

Abstract: A wound fluid collection system includes a canister adapted to collect bodily fluids from a tissue site. The canister includes an acoustic transducer adapted and positioned to insonify a cavity within the canister, the cavity being defined by a wall of the canister and the bodily fluids collected within the canister. A resonant frequency may be calculated based on a resulting received signal from the insonification. The resonant frequency may indicate a volume of the cavity within the canister. The difference between a known volume of the canister and the calculated volume of the cavity provides the volume of bodily fluid collected in the canister.

Abstract: A circulatory assist system is disclosed, the system including an implantable electrical device having an electric motor, an implantable controller connected to the implantable electrical device, and an implantable power source connected to the controller for supplying power to the controller. The controller is attachable to a first side of a percutaneous connector. A second side of the percutaneous connector, opposite to the first side, allows external connectivity to said controller.

Abstract: A method for calculating or estimating or approximating one or more values representing parameters of a patient includes the step of interpolating or extrapolating of at least one later value of a first parameter taking into account at least one earlier value of the first parameter, at least one earlier and at least one later value of a second parameter, and a mathematical relation between the first and the second parameter. An apparatus, a blood treatment device, a digital storage device, a computer program product, and a computer program are also described.

Abstract: A dialysis machine comprising a fluid circuit for providing a dialysis fluid to a dialyzer is disclosed. The fluid circuit comprises a tube with a first valve for providing a disinfectant fluid for disinfecting at least a part of the fluid circuit at disinfection of the dialysis machine. The tube with the first valve is arranged to provide the disinfectant fluid upstream the dialyzer and at a position in the fluid circuit where pressure is, during treatment, such that a pressure gradient between ports of the first valve is provided, the ports comprising at least a disinfectant fluid port and a fluid circuit port, such that the disinfectant fluid port of the first valve is enabled to be safely connected to a source of disinfectant also during treatment. A method of controlling such a dialysis machine and a computer program for controlling are also disclosed.

Abstract: This is to provide a blood filter comprising a porous element; and a copolymer which exists in at least a part of a surface of the porous element, and which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b), wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims.

Abstract: A medicament delivery system and method of use. A medicament delivery system comprising a medicament, a medicament delivery device, an alerting device, operating instructions, and a carrying case. The medicament can be glucagon for use with Type 1 diabetics. A method where a person assisting a patient in medical distress locates the patient's medicament injection pen by using an alerting device that sends a signal to the pen's carrying case, and where a triggered alarm in the case alerts the assisting person of the pen's whereabouts. A method where a person assisting a patient in medical distress provides a medicament to the patient by pushing an actuator on a medicament injection pen until a diaphragm separating two chambers in the pen breaks allowing medicament and diluting solution to mix, and where the assisting person then injects the mixture into a soft tissue of the patient.

Abstract: An intravenous line organizer for organizing a plurality of intravenous lines, each being interconnected with a medicament pump is disclosed. A plurality of holders is defined by an elongated tubular wall defining an axis, with adjacent of the tubular walls having parallel axis and being interconnected by a joining member. Each of the tubular walls defines an entry way for receiving an intravenous line used for delivering medicament to a patient. The entry way includes mating appendages for retaining the intravenous line within the holder.

Abstract: An infusion pump operable with a syringe having a syringe barrel and a syringe plunger includes a housing having a compartment to receive the syringe and defining a wall, and a syringe clamp moveable towards and away from the wall, the syringe clamp contacting the syringe barrel; a drive mechanism supported and structured and arranged to contact and end of the syringe plunger so as to be able to move the syringe plunger within the syringe barrel; a syringe barrel size sensor including a magnet operably coupled to the syringe clamp, and a sensing member supported by the housing and configured to generate an output indicative of a magnetic field associated with the magnet; and software installed on the pump and programmed to use the output to determine a size of the syringe barrel received by the compartment.

Abstract: Provided is a flexible and conformal wearable, self-contained medical device. The medical device comprises an integral housing formed by a flexible upper portion and a flexible lower portion joined along their perimeters. The medical device is also provided in a plurality of shapes and configurations for increasing the flexibility and conformability of the housing. The components contained within the housing, such as a drug reservoir, printed circuit board, and power supply are preferably constructed from flexible materials and are formed, connected and positioned according to the configuration of the housing in a manner for enhancing flexibility of the housing. A thermal bubble micropump is provided for controlling flow of a drug from the flexible reservoir, that utilizes a thermal resistor provided locally to a thermal expansion fluid that causes a surrounding membrane to expand and displace a volume of drug to be provided to the user.

Abstract: Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.

Abstract: A controlled delivery drive mechanism includes a drug container having a barrel and a plunger seal; a drive housing within which at least initially partially resides a piston having an interface surface and a drive rack; and a power spring. The piston is configured to contact and axially translate the plunger seal within barrel. The mechanism may be configured to convert rotational movement of a drive pinion to axial translation of the drive rack, or to convert axial force of a linear power spring into torsional motion of a drive pinion. A regulating mechanism meters the drive pinion such that the piston is axially translated at a controlled rate. The drug container may contain a drug fluid within a drug chamber for drug delivery at a controlled rate. The regulating mechanism may be an escapement regulating mechanism. A drug delivery pump includes such controlled delivery drive mechanisms.

Abstract: The disclosure relates to a selectively and concurrently implementable multi-probe microdrive apparatus. Specifically, the disclosure relates to an apparatus configured to selectively and reversibly couple and/or decouple at least one holder to, and/or from an actuator independently, wherein the actuator is configured for controllably and concurrently move any coupled holder. The holder adapted to have a stimulating and/or recording electrode coupled thereon.

Abstract: The presently disclosed subject matter relates to an addition to a medical applicator in general and in particular to an addition to a medical applicator for applying on a surface a curable liquid substance having multi components.

Abstract: An acoustic line tracing system for tracing a fluid transfer system tubing line includes an acoustic receiver operably connectable to the tubing line and configured to receive the vibratory signal. The acoustic receiver includes a vibration sensor disposed to contact the tubing line and configured for detecting vibration of the surface of the tubing line caused by the vibratory signal, and an indicator producing at least one of an audio and a visual cue when the vibration sensor detects the vibratory signal.

Abstract: A container designed to contain a fluid medicament and adapted to cooperate with a delivery device for delivering the fluid medicament comprises an electrically operable sensor system for measuring at least one physical or chemical parameter value related to the container and/or fluid medicament therein, wherein the sensor system comprises an optical receiver designed to receive optical radiation energy and to transform said optical radiation energy into electrical energy for operating the sensor system.

Abstract: Disclosed is an injection gadget corresponding to an end-effector such as a rescue robot or the like.

Abstract: The present invention relates to a medical device protection assembly and to a respective medical device. The protection assembly comprises at least one reorientation member being connectable with a medical device and being operable to orient the medical device into a predefined orientation in the event the medical device is subject to a free-fall.

Abstract: A medicament delivery device for a disposable container having at least one chamber for a liquid medicament encapsulated in the container by at least one movable plunger. The medicament delivery device is elongated along a longitudinal axis (A), has proximal and distal ends, and includes a housing with proximal housing section configured for accommodating the disposable container and a distal housing section; a plunger rod configured for contacting the movable plunger; and a drive mechanism arranged in the distal housing section for applying, when the medicament delivery device is activated, a force on the movable plunger in a proximal direction via the plunger rod. The plunger rod includes an outer periphery having at least two axially separated recesses or cut-out portions for retaining liquid medicament that leaks along the plunger rod toward the drive mechanism.

Abstract: A medical cartridge containing multiple doses of a medical drug is disclosed. An outlet end is arranged to be connected to an injection needle for delivering the medical drug. The medical cartridge comprises a one way valve arranged in an interior part of the medical cartridge at a position near the outlet end. The one way valve allows a fluid flow from the interior of the medical cartridge towards the outlet end, but prevents a fluid flow from the outlet end towards the interior of the medical cartridge. Thereby the risk of contamination of the medical drug remaining in the cartridge is minimized.

Abstract: A syringe mechanism for the auto-regeneration of the dermis is provided. The syringe mechanism includes: a liquid syringe filled with liquid in a cylinder thereof, a piston inserted into a top of the cylinder, a discharge portion formed at a bottom portion of the cylinder, and screw threads formed around the discharge portion; and an injecting member having a cylindrical body portion, an inlet portion formed to be inserted and coupled with the discharge portion at a top end of the cylindrical body portion, and a coupling portion formed to be coupled with the screw threads around the inlet portion, the screw threads and the coupling portion rotated and inserted so as to be fastened to the liquid syringe so that liquid is injected into the top portion of the body portion via the liquid syringe.

Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have an integrated cassette syringe movably disposed within the housing, for holding a drug, and a locking arrangement for interlocking the integrated cassette syringe with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the integrated cassette syringe. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein.

Abstract: The present invention relates to a medicament delivery device. The medicament delivery device may include an operation member configured to act on a medicament container for expelling a medicament. The device may configured to hold the operation member in a pre-tensioned state. The device may include an activation member configured to interact with the operation member to release it from the pre-tensioned state. The device may further comprise feedback. For example, the feedback may include generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: The invention refers to an injection device comprising a housing (10), containing a cartridge (170) with an amount of liquid to be dispensed, a drive sleeve (41), which is rotationally constrained to the housing (10) during dose setting and spring driven rotatable relative to the housing (10) during dose dispensing, a dose dial member (60) for setting a dose to be dispensed, which is rotatable relative to the housing (10) during dose setting and during dose dispensing, and which is rotationally coupled to the drive sleeve (41) during dose dispensing. The device further comprises a last dose protection mechanism (41, 50, 60) for preventing the setting of a dose, which exceeds the amount of liquid left in the cartridge (170), with a limiter (50), which is interposed between the drive sleeve (41) and the dose dial member (60). Further, the device comprises two different display members (110, 120), each indicating the set dose.

Abstract: An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.

Abstract: A medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod. The stopper being slidably disposed within the reservoir and sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap includes a body having a proximal end, a distal end, and a flange provided adjacent the distal end. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

Abstract: A plunger, a needle assembly and a retractable syringe comprising same are provided. The plunger comprises a plunger member and a plunger outer having a lock spring that prevents or impedes movement of the plunger member after needle retraction. The plunger further comprises another locking member for engaging the barrel to prevent or impede further movement of the plunger outer after delivery of fluid contents. The plunger member has a plunger seal which engages a retractable needle of the needle assembly for retraction. The retractable needle comprises a cannula and needle body with a plurality of fluid channels that co-operate with a fluid conduit of the plunger seal to efficiently direct fluid to the cannula. A needle retainer comprises a plurality of barbed arms releasably coupled to the needle body, whereby an ejector with tabs facilitates release of the retractable needle from the needle retainer to allow compressed spring-driven retraction.

Abstract: A safety syringe has a barrel, a pushing element, a retracting element, and a needle group. The barrel is hollow and has a needle-group mounting end, an operating grip end, and a barrel lumen. The pushing element is retractably mounted in the barrel lumen and has a pushrod chamber. The retracting element is airtightly and slidably mounted in the pushrod chamber. The needle group is connected to the needle-group mounting end of the barrel. The present invention can pull the retracting element to move relative to the pushing element to form a low pressure condition in the pushrod chamber as a vacuum status. After the injection, a vacuum attraction force in the pushrod chamber can retract the used needle group into the pushrod chamber for safe use of the safety syringe.

Abstract: The present invention provides a method of obtaining a classification boundary, to limit an axial depth in a puncturing operation. The following steps of method comprises: At first, obtaining a plurality of tomographic images from the axial depth of a tissue is performed. Then, obtaining a plurality of characteristic values from the tomographic images, the characteristic values are classified by a Support Vector Machine method. A classification boundary will be obtained through a distribution of the graph for defining a specific compartment of the tissue. In addition, an automatic recognition method and system using the above mentioned method are also disclosed in the present invention.

Abstract: The present disclosure provides devices for implanting tissue or other substances within the body. The devices can include a feedback mechanism, which can assist a surgeon in implanting the tissue or other substances by preventing excess shear force or pressure on the tissue or substance to be implanted.

Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port.

Abstract: A personal vapor inhaling unit is disclosed. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled.

Abstract: The present disclosure relates to a dose indicator for a pressure-actuated metered dose inhaler (pMDI) device. In an embodiment, the dose indicator comprises a chassis element having a viewing portion, a display element located within the chassis element, a resilient deformable element, and an indexing element having an axis, translation of the indexing element along its axis from a first position to a second position causing deformation of the resilient deformable element in the same direction as translation of the indexing element resulting in generally greater displacement of portions of the resilient deformable element nearer to the axis relative to portions thereof further from the axis, the displacement of the portions of the resilient deformable element in the same direction as translation of the indexing element inducing indexing of the display element from a current position to a subsequent position relative to the viewing portion of the chassis element.

Abstract: Disclosed is a method for oral administration of a liquid containing an active substance to a subject for improved absorption into the subject's bloodstream. It includes the steps of providing a delivery device containing the liquid and having a mouthpiece for directing the liquid in a defined direction during delivery; directing the mouthpiece toward a localized area of the subject's mouth being especially suitable for relatively increased uptake and relatively faster onset of action of the active substance; and delivering a measured amount of the liquid directly to the area using the device. Also disclosed is a spray device that includes a container capable of holding a liquid containing an active substance, and a mouthpiece constructed to dispense the liquid in a defined direction and directly to a localized area of a subject's mouth, the localized area being the oral vestibule.

Abstract: A flow generator includes a housing, a blower structured to generate a flow of pressurized breathable air, and a suspension device to support the blower within the housing and provide a pressure seal between low and high pressure sides of the blower. The suspension device includes a bellows-like portion provided along the perimeter of the blower to absorb shock applied at least radially to the blower and one or more cones provided along upper and/or lower sides of the blower to absorb shock applied at least axially to the blower.

Abstract: A system and method are configured to utilize patient effort to increase cough flow of a subject by limiting airway collapse by causing a series of exsufflation events over an individual exhalation of the subject. A single exhalation of the subject is segmented into a series of exsufflation events by a processor configured to toggle a pressure regulator between a first airway closed mode and a second airway open mode. The processor is configured such that the transitions between the closed and open modes are initiated based on predetermined timing or based on output signals generated by sensors monitoring one or more gas parameters (for example, pressure) in the airway of the patient.

Abstract: Pulmonary ventilator methods and systems are provided winch include a housing having a user interface control panel; a pneumatic circuit for delivering a high frequency pressure wave from the housing to a patient lung; a variable volume disposed within the housing including a stationary plate secured to the housing and a reciprocating plate pivotably mounted with respect to the stationary plate; and a magnet assembly disposed within the housing and configured to pivot the reciprocating plate. The variable volume may also include a resiliently contractible section extending between and joining a portion of the stationary plate and a portion of the reciprocating plate, wherein the resiliently contractible section may be in the form of a bellows and/or a pleated material.