Abstract: A robotic assistant provides active support for disabled users and may take the approximate form of a cane or a walker.

Abstract: A system for assisting a person to rise from or recline to a sitting position is disclosed employing a walker or cane having a connector that enables attachment and detachment with an anchor attached to the floor.

Abstract: An adjustable massage roller device for rolling massage of body parts includes a tube that defines an interior space. A bladder is positioned in the interior space. The bladder is substantially complementary to the interior space when the bladder is fully inflated. A housing is coupled to a respective opposing end of the tube. A power module and a pump are coupled to and positioned in the housing. The pump is operationally coupled to the power module. The pump is fluidically coupled to the bladder. The pump is configured to motivate air into the bladder, such that the bladder is inflated and occupies the interior space of the tube. The tube is configured to position between a body part of a user and a surface such that the tube is configured to roll on the body part as the user moves laterally relative to the surface.

Abstract: A legs and feet massage apparatus for providing massaging effects to the legs and feet of a user is disclosed. The legs and feet massage apparatus includes a frame, a feet massage roller assembly, and limit means. The frame includes opposing guide rails and at least one connecting bar. Each guide rail includes an upper end, a lower end, a vertical section, a horizontal section, a connecting section, an outer side, an inner side, and a guide channel. The roller assembly includes feet massage roller devices and a motor. The roller devices are moved along the guide channels by the motor providing power to rotate the roller devices whereby the roller devices move along the guide channels while also providing massaging effects to soles of the feet and backsides of the ankles and calves of the user. A massage chair having a legs and feet massage apparatus is also disclosed.

Abstract: There is disclosed an apparatus for treating a sexual dysfunctional female patient, comprising a stimulation device adapted to stimulate an erectile blood passageway to increase the amount of blood in the female erectile tissue and thereby obtaining engorgement with blood of the female erectile tissue by affecting said erectile blood flow passageway. Moreover there is disclosed a system and an operation method for treating a sexual dysfunctional female patient.

Abstract: A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion includes touch-points or a wave that transmit the tapping motion to skin in contact with the textured portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.

Abstract: The majority of adult devices have been designed for an individual to hold. However, it would be beneficial to provide users with a range of adult devices that support their use either in a hands free manner and/or are compatible with being worn by the user for varying periods of time from intermittent/occasional short durations through to extended wearing such as all day for example. In order to provide such wearable devices being able to separate the drive means from the stimulation means provides increased design flexibility as well as allowing different designs of adult device to be implemented as the design flexibility within the appropriate regions of the user's anatomy increases when the large vibratory motors are removed and connected to the stimulation means via flexible drive shaft. Further, beneficially, flexible drive shafts allow operation as the user moves during normal activities, such as sitting, standing, walking, etc.

Abstract: Chest compression machine systems and methods adjust the administration of patient treatment based on received physiological parameter measurements, such as a CO2 measurement. Adjustment of the administered chest compressions can include adjusting one or more chest compression parameters, such as the depth of the administered compressions, the administration of active decompressions, adjusting the height of active decompression, adjusting the rate of compressions and/or active decompressions and/or other changes to one or more properties, or characteristics, of the administered chest compressions and/or active decompressions.

Abstract: An autonomous mechanical CPR device is disclosed having a CPR unit attached to a free-standing support assembly. In operation, a victim is placed in the support assembly such that the CPR unit can compress the victim's chest. The CPR device is preferably portable, and it provides the recommended depth of chest compression at the recommended rate. The CPR unit has a quick disconnect locking system with an insert that fits into a lock.

Abstract: A system includes a vial stabilizer base having a first body and a plurality of fingers projecting from the first body, with the plurality of fingers being annularly disposed about the first body, and a vial adapter having a second body and a plurality of arms projecting from the second body. The second body defines a passageway. The plurality of fingers of the vial stabilizer base defines a socket having a first seat configured to receive a vial and a second seat configured to receive the vial adapter.

Abstract: Devices, assemblies, and methods for arranging and dispensing medication are shown and described. In one embodiment, a medication dispensing assembly includes a first single dose tray having a plurality of dosage complexes and a first label face, and at least a second single dose tray having a plurality of dosage complexes and a second label face. Each dosage complex has a unitary blister pocket adjacent to an L-shaped opening. In other embodiments, a single dose medication tray includes a label platform and a plurality of dosage complex groupings. The result is devices and methods to orient and dispense individually packaged medications.

Abstract: An apparatus and method for dispensing medication include a medication dispensing portable communication device case. The medication dispensing portable communication device case has a device recess configured to removably hold at least a portion of a portable communication device therein. The portable communication device case has a dispensing port stoppered by a covering structure and a dial medication storage recess. The dial medication storage recess extends through a backplane of the device recess and a dial medication storage portion is held within the dial medication storage recess. The dial medication storage portion is located adjacent to the device recess. The dial medication storage portion includes a pill plate that has a plurality of individual cups, and the pill plate is placed inside a pill plate housing that is covered by an outer cover.

Abstract: A medication adherence system for facilitating adherence to a medication dosage schedule is provided, comprising a smart case to receive or adhere to a medication pack, a sensor for detecting a medication event, and a tangible computer readable medium interface for users to obtain feedback regarding their adherence to their respective medication dosage schedules.

Abstract: The present invention relates to a dental composition comprising an initiator system comprising a sensitizer compound having an acylsilyl- or acylgermyl-group and a specific coinitiator compound. The present invention also relates to an initiator system consisting essentially of the sensitizer compound having an acylsilyl- or acylgermyl-group and a coinitiator compound wherein a C—H bond dissociation energy is less than 95 Kcal/mol. Furthermore, the present invention relates to the use of this initiator system for the preparation of a dental composition.

Abstract: Provided herein are dental compositions and methods for use in dental cementation applications.

Abstract: The present invention provides a patch for attaching to teeth or a surrounding part of teeth, and the patch can be easily removed by tooth brushing alone.

Abstract: The invention relates to a skin lightening composition, particularly to a composition in the form of a mask that can be applied to the desired topical surface for providing instant lightening benefits without the disadvantages of unnatural whiteness. This is effective due to the inclusion of high amounts of whitening particle along with select film forming polymer while ensuring that the amount of humectants is below a certain value.

Abstract: A method to prepare a cream product includes separately preparing an exclusively aqueous phase and a mixed fatty/aqueous phase, and assembling and emulsify the exclusively aqueous phase and the mixed fatty/aqueous phase.

Abstract: According to the present invention, there are provided microcapsules comprising an emulsion droplet encapsulated by a metallic film, wherein the emulsion droplet comprises an emulsifier disposed around a liquid core material. The present invention also provides processes for preparing the microcapsules, as well as formulations comprising the same. The present invention further provides for certain consumer products comprising: an adjunct material; and a plurality of microcapsules, said microcapsules comprising: an emulsion droplet encapsulated by a metallic film, wherein the emulsion droplet comprises an emulsifier disposed around a liquid core material.

Abstract: Provided is an oral care composition, e.g., a dentifrice, comprising a calcium abrasive, e.g., calcium carbonate, potassium nitrate (KNO3), and a basic amino acid, in free or salt form, e.g., arginine, in free or salt form, wherein the potassium nitrate is present in an amount of 0.1-1% by weight of the composition and methods of using the same.

Abstract: An oral care composition comprising at least one metal phosphate chosen from stannous phosphate, magnesium phosphate or aluminum phosphate; and at least one fluoride ion source. The at least one phosphate is added to the oral care composition as a preformed salt. Methods of administering the oral care composition to a subject are also disclosed.

Abstract: The present invention provides silicon oxide-coated zinc oxide in which, in a silica coating formed of a silicate alkali metal salt, the elution of zinc ions is suppressed, a method for preparing the same, a composition containing silicon oxide-coated zinc oxide, and a cosmetic material. The silicon oxide-coated zinc oxide of the present invention is silicon oxide-coated zinc oxide formed by coating surfaces of zinc oxide particles with a silicon oxide coating, in which an average primary particle diameter of the zinc oxide particles is more than 50 nm and 500 nm or less, and when held in a buffer solution having a pH of 5 for 1 hour, an elution ratio S of the zinc oxide defined by following Expression (1) is 50% or less.

Abstract: The present invention provides compositions and methods of using the compositions as personal care products and other consumer and industrial products, wherein the compositions comprise bio-based farnesene and/or compounds derived from the bio-based farnesene.

Abstract: A cosmetic composition is provided, the composition comprising a safe and effective amount of a skin care active with A log P less than ?2.0, a safe and effective amount of a fatty alcohol; and a safe and effective amount of a glyceryl ester. The combination of fatty alcohol and glyceryl esters surprisingly enhances penetration of skin care actives with low A log P values into skin.

Abstract: A non-aqueous hair leave-on composition directed to an aqueous hair leave-on composition for hair frizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following class: 1) Class II having the structure selected from: a) wherein R is hydrogen or metal ion, R6 is methyl, ethyl, propyl, alkenyl or phenyl having less than 12 carbon atoms and wherein R7, R8, R9, R10, R11, R12 are hydrogen, methyl, ethyl, propyl, phenyl, hydroxyl, methoxy or ethoxy groups; b) an alcohol wherein R13 is an alkyl, alkenyl, straight or branched carbon chains and; and wherein R14 is hydrogen, hydroxyl, alkyl, methyl, ethyl and propyl wherein the structure of such alcohol contains less than 20 total carbon atoms; c) alcohol comprising an unsaturated double bond in the C2 position.

Abstract: The subject of the present disclosure is a method for coloring of keratinous fibers, particularly human hair, including the following steps in the specified sequence: A) Treatment of the fibers with a hydrous pre-treatment agent (V), B) Treatment of the fibers with a hydrous coloring agent (F), wherein the pre-treatment agent (V) has a pH value of from about 1.0 to about 5.0 and the coloring agent (F) has at least one partially-oxidizing acid dye and a pH value of from about 5.0 to about 9.5. An additional subject of the present disclosure is a multi-component package unit (kit) including a pre-treatment agent (V) and a coloring agent (F).

Abstract: A composition directed to a non-aqueous hair leave-on composition for hair fizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following class: Class I having the structure selected from: wherein R? is —COOY, sulfonic acid, or C?CH—COOY, Y is hydrogen or a metal ion, R1, R2, R3, R4, R5 is hydrogen, methyl, ethyl, propyl, vinyl, allyl, methoxy, ethoxy, hydroxyl, halogen, sulfate, sulfonate, nitro, or —CH?CH—COOR, and wherein the moisture control material is an acidic material and further wherein the moisture control material has a % Protein binding higher than 20 and Molecular Volume lower than 500 and Partition coefficient octanol to water (log P) lower than 3 and hydrogen binding higher than 10 and pKa lower than 5.

Abstract: A multi-film delivery system for a multi-component tooth whitening, desensitization and remineralization composition is disclosed which comprises a first orally dissolvable film made of a liquid-soluble or liquid dispersible polymer system containing an activation compound or complex and desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, and a separate second orally dissolvable film made of an inert hydrophilic polymer system containing a tooth whitening compound, such as hydrogen peroxide or sodium perborate, stabilizers and thickeners, and/or desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, which, when applied together on teeth surfaces, the activation compound/complex on the first film activates the tooth whitening compound in the second film, and accelerates the release of active bleaching radicals for accelerated whitening action. The first and second films are maintained separate from one another until application.

Abstract: The present specification relates to an oil-in-water type emulsion cosmetic composition containing an amphiphilic anisotropic powder and ceramide, wherein the amphiphilic anisotropic powder contains a first polymer spheroid which is hydrophilic and a second polymer spheroid which is hydrophobic, wherein the first polymer spheroid and the second polymer spheroid bind by at least partially penetrating the other polymer spheroid, wherein the first polymer spheroid has a core-shell structure, wherein the shell contains a functional group, and wherein the ceramide contains oil phase ceramide included in oil phase and ceramide particles included in water phase.

Abstract: The present invention provides a solid cosmetic composition comprising (i) corn starch in an amount of from about 20% to about 40%; (ii) bulking agent in an amount of from about 20% to about 50%; (iii) surfactant in an amount of from about 5% to about 30%; and (iv) glycerine in an amount of from about 15% to about 30%, present in an amount by weight of the total composition.

Abstract: Described herein are methods and compositions that contain a soluble polyglucosamine or polyglucosamine derivative for use in oral health. The compositions are useful for, e.g., reducing bacteria (e.g., by clumping and removing) or disrupting a biofilm in the mouth of a subject, reducing dry mouth, and reducing oral inflammation.

Abstract: A sunscreen cosmetic exerts stably an excellent ultraviolet shielding effect without undergoing photodegradation even in a system where 4-tert-butyl-4?-methoxydibenzoylmethane and ethylhexyl methoxycinnamate coexist. The sunscreen cosmetic comprises (a) 0.5-5.0 mass % of 4-tert-butyl-4?-methoxydibenzoylmethane, (b) 3.0-10 mass % of ethylhexyl methoxycinnamate, (c) 5.0 mass % or more of an amphipathic substance, and (d) a liquid oil component containing an ester oil having an IOB of 0.05-0.60, characterized in that the contents of components (a), (b) and (c) satisfy the requirement 0.5?[(a)+(b)]/(c)?3.5.

Abstract: The present application discloses a hairstyling composition, particularly for curly hair, which produces tight, long-lasting curls without requiring the use of high heat applied to the hair. The composition comprises a sulfonate-based copolymer (such as sodium polystyrene sulfonate), an aqueous polyurethane dispersion (such as polyurethane-34) and a cosmetically-acceptable carrier (such as water). The method of styling hair using the defined composition, without requiring the application of high heat to the hair, is also disclosed.

Abstract: The invention relates to a composition for skin improvement or repair, comprising an extract of Boswellia frereana; a method of producing said composition; and a method of skin improvement or repair comprising use of said composition.

Abstract: A method for protecting skin is provided, wherein the method comprises administering to a subject in need an effective amount of an orchid callus extract, and the extract is a polar solvent extract of a callus of orchid leaves. The method is especially for moisturizing skin, increasing skin tenderness, increasing skin abundance, increasing skin elasticity, tightening skin, reducing skin textures, delaying skin aging, assisting in increasing content of collagen, repairing skin tissues, preventing skin lesions, and/or promoting wound healing.

Abstract: Hormone formulations, dosage units including the hormone formulations, and methods of use relate to a controlled release formulation, which includes hormones, e.g., progesterone. Formulations and methods are for controlling the reproductive cycle and/or ovulation of a female mammal, for example, to promote ovulation in a female mammal or synchronizing the ovulation or heat/estrus of a group of female mammals. In addition, formulations are for increasing the likelihood that a female mammal becomes pregnant, for example, after insemination or embryo transference. In addition, formulations are for reducing the anestrous period in a female mammal.

Abstract: A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.

Abstract: A substance delivery device comprises a substrate, a plurality of dissolvable supporting structures and a plurality of carriers. The substrate attaches to a tissue. The dissolvable supporting structures are disposed on the substrate. The carriers are disposed on the dissolvable supporting structures and encapsulating substances. The present invention further provides a substance delivery method. The substance delivery device and the substance delivery method of present invention is advantageous for providing sustained release effect and rising the applicability of transdermal or transmucosal delivery techniques.

Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.

Abstract: The present invention relates to an ophthalmic aqueous composition containing PGF2? analogues for treating ocular hypertension and glaucoma, to a method for treating ocular hypertension and glaucoma by administering said composition to a subject in need of such treatment, and to a method for increasing aqueous solubility and stability of PGF2? analogues in an aqueous composition.

Abstract: A glucose strip system which includes a container having a top surface, a bottom surface, and an inner volume, and at least one glucose strip having at least one flavoring agent. The glucose strip system includes the container and the at least one glucose strip. The container has the top surface, the bottom surface, and the inner volume. The bottom surface is substantially planar allowing at least one glucose strip able to lay flat within the inner volume between the top surface and the bottom surface of the container. At least one glucose strip is able to be orally administered by a user for regulating, sustaining, and increasing blood sugar levels of the user.

Abstract: The present invention provides compositions comprising nanoparticles comprising: 1) a drug, such as a hydrophobic drug derivative; and 2) a carrier protein. Also provided are methods of treating diseases (such as cancer) using the compositions, as well as kits and unit dosages.

Abstract: Particles are disclosed. Methods of making and using the particles are also disclosed.

Abstract: The invention disclosed herein is a highly concentrated powdered oleoresin composition comprises oleoresin(s), Mineral hydroxide(s)/oxide(s)/chloride(s)/carbonate(s) and optionally comprises organic/inorganic acid(s); wherein said composition has enhanced stability and increased bioavailability. The invention also disclosed herein a process for preparation of said composition.

Abstract: Stable pharmaceutical formulations and drug delivery devices are disclosed. In certain embodiments, the drug delivery device contains a reservoir when implanted into a patient is in partial contact with the tissue environment. The reservoir remains in contact with the environment via a porous structure in the housing of the delivery device. The reservoir contains a combination of the therapeutic biomolecule and a second molecule that serves to stabilize and restrict the solubility of the therapeutic biomolecule, thereby controlling the amount of therapeutic biomolecule that is in solution. The concentration of the soluble therapeutic biomolecule or the size of the surface area of the porous structure controls the rate of delivery of the therapeutic biomolecule to the target tissue.

Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise physiologically active inorganic metal salts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

Abstract: A two-compartment capsule includes a body, a diaphragm between which seals off the body and provides a first compartment to hold a first ingredient, and a cap applied to the body whereby a space between the inner portion of the cap and the diaphragm defines a second compartment for holding a second ingredient. This disclosure also provides certain ranges for the volumes of the first compartment and the second compartment, as well as a volume ratio of the first compartment to the second compartment, lengths of the first and second compartments, and the length of contact between a sidewall of the diaphragm and a sidewall of the body. Furthermore, particular ingredients and formulations for the two-compartment capsule where volume is critical for a therapeutic effect are disclosed.

Abstract: A computer-implemented method for image-guided delivery of a nanoparticle mixture to a target tumor located in a region of interest includes selecting a non-hypoxic delivery location within the region of interest for delivery of a non-bacteria-associated nanoparticle component included in the nanoparticle mixture and selecting a hypoxic delivery location within the region of interest for delivery of a bacteria-associated nanoparticle component included in the nanoparticle mixture. An image-guided delivery and monitoring process may then be performed.

Abstract: The present invention relates to nanoparticles of albumin loaded with 5FU and/or with a precursor thereof. Further, the present invention relates to a pharmaceutical composition or a 5FU delivery system and/or a precursor thereof comprising nanoparticles. The present invention also relates to a method for producing said nanoparticles and the use of the nanoparticles, the pharmaceutical composition or the 5FU delivery system and/or a precursor thereof as a medicament, in particular for use in treatment of tumours.

Abstract: A method of delivering a health care active having the steps of administering to a mammal in need of a health benefit or a treatment for a health condition a personal health care article and consuming the article. The article contains one or more filaments that contain a backbone material, a health care active and optionally aesthetic agents, extensional aids, plasticizers, and crosslinking agents.