Patents Issued in December 11, 2018
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Patent number: 10149939Abstract: Provided is a medicament delivery device (100) comprising a tubular housing (110), having a proximal end (111) and an opposite distal end (112), an actuator means (119, 120), slidably and coaxially arranged inside the tubular housing (110) wherein is provided an inter-locking mechanism (119, 413) between the a cap (410) and the housing (110), enabling the cap (410) to freely spin, i.e. it is impossible to open the cap (410), until the medicament delivery device (100) has been properly activated by an activator means (160).Type: GrantFiled: April 21, 2015Date of Patent: December 11, 2018Assignee: SHL Group ABInventors: Lucio Giambattista, Antonio Bendek
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Patent number: 10149940Abstract: A connector which is detachably connected to a cylindrical section is prevented from unintentionally disconnecting and breaking. The connector has inner and outer cylinder members. The inner cylinder member has an engagement plate protruding from the inner peripheral surface of an inner cylinder body and engaging with a recess formed in the outer peripheral surface of the cylindrical section, and also has slits arranged radially and extending from the engagement plate to a part of the inner cylinder body. The engagement between the recess and the engagement plate restricts the axial movement of the inner cylinder member relative to the cylindrical section. When the outer cylinder member is mounted on the inner cylinder member, the inner peripheral surface of the outer cylinder member is in contact with the outer peripheral surface of the inner cylinder member, and the displacement of the engagement plate in the diameter expansion direction is restricted.Type: GrantFiled: July 9, 2013Date of Patent: December 11, 2018Assignee: NIPRO CORPORATIONInventors: Hideki Yagi, Naoaki Yasumura
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Patent number: 10149941Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a flexible stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The barrel includes anti-reflux structure for holding said stopper in a partially deflected position after fluid has been delivered from the chamber and the stopper is being force against the distal end of the chamber.Type: GrantFiled: May 27, 2015Date of Patent: December 11, 2018Assignee: Becton, Dickinson and CompanyInventors: Thomas A. Alheidt, Tracy Ray Hottovy, Dustin Drake
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Patent number: 10149942Abstract: A medicament delivery device includes a housing arranged to accommodate a medicament container, and a drive unit operably arranged to act on an accommodated medicament container for expelling a dose of medicament. The drive unit includes a plunger rod, a force element operably connected to the plunger rod, a connector arranged to releasably hold the plunger rod, an actuator element operably arranged to the connector, and a manually operable actuator arranged to act on the actuator element for releasing the connector when operated. A safety device is arranged to releasably hold the actuator element in a locking position with the connector, preventing unintended release of the plunger rod.Type: GrantFiled: August 21, 2014Date of Patent: December 11, 2018Assignee: CAREBAY EUROPE LTDInventors: Stefan Lööf, Stefan Morén
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Patent number: 10149943Abstract: A cartridge interface assembly drives a stopper in a drug reservoir or a drug delivery device. An anti-rotational guide optionally moves along an axis of a cavity of the reservoir. The anti-rotational guide is optionally slidably anti-rotationally coupled to a housing of the drug delivery device. A telescoping plunger driver may include a proximal shaft and distal shaft that telescope by relative rotation. The distal shaft is optionally slidably anti-rotationally coupled to the anti-rotational guide. The shafts are optionally oriented along said axis. In some embodiments, rotating the proximal shaft with respect to the anti-rotational guide moves the guide along said axis with respect to the housing and moves the distal shaft along the axis with respect to the anti-rotational guide.Type: GrantFiled: May 29, 2015Date of Patent: December 11, 2018Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
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Patent number: 10149944Abstract: A syringe is applied to connect with a vial and a needle, and the syringe includes an outer protecting housing, a connecting ring, a vial housing, an inner tube, a bidirectional guiding tube device, a screwing sleeve, a ratchet, a spiral rotating rod and an injection rod unit. The connecting ring is mounted on a front end of the outer protecting housing, and the vial housing is connected with the connecting ring for assembling a vial. The inner tube, the bidirectional guiding tube device, the screwing sleeve, the ratchet, the spiral rotating rod and the injection rod unit are mounted in the outer protecting housing. The injection rod unit is rapidly pulled backward and then is pressed to move forward for injecting.Type: GrantFiled: September 23, 2016Date of Patent: December 11, 2018Assignee: CC Biotechnology CorporationInventor: Chin-Min Yeh
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Patent number: 10149945Abstract: An injection device provides a casing which accommodates or forms a reservoir for a liquid drug; a plunger rod which can move relative to the casing in an axially forward direction to deliver the drug; and a dosing means which can move in the forward direction relative to the casing to prime the reservoir and which can rotate relative to the casing for selecting a dose to be injected. Rotation of the dosing means relative to the casing is prevented until a priming operation for priming the reservoir is completed. The dosing means comprises a dosing control means which is configured to enable rotation of the dosing means at the end of the priming stroke for selecting the dose and to prevent a rotation of the dosing means back into the position which the dosing means had at the end of the priming stroke relative to the casing.Type: GrantFiled: March 20, 2015Date of Patent: December 11, 2018Assignee: TECPHARMA LICENSING AGInventors: Ulrich Moser, Jürg Hirschel, Markus Tschirren, Philipp Wälchli, Peter Stettler, Patrick Sackermann, Christian Schrul, Martin Berger, Nicolas Binggeli
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Patent number: 10149946Abstract: An assembly for use in a drug delivery device includes a cartridge, a housing and a cartridge holder. The cartridge holder is releasably attached to the housing. The assembly includes a piston rod configured to move from a start position to an end position to dispense a dose of medication when the cartridge holder is attached to the housing, and the piston rod is configured to be reset to the start position when the cartridge holder is detached from the housing. The assembly further comprises a flexible element configured to axially fix the cartridge in the cartridge holder when the cartridge holder is attached to the housing. Furthermore, the assembly comprises a guiding element in threaded engagement with the piston rod. The flexible element is configured to fix the guiding element with respect to a housing of the drug delivery device when the cartridge holder is attached to the housing.Type: GrantFiled: May 8, 2014Date of Patent: December 11, 2018Assignee: Sanofi-Aventis Deutschland GMBHInventor: Andreas Bernert
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Patent number: 10149947Abstract: A drug delivery device for setting and dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive spindle operably engageable with the piston rod during dose dispensing and a drive member axially displaceable relative to the drive spindle against the action of a spring element during dose setting and being threadedly engaged with the drive spindle to form a spindle gear.Type: GrantFiled: April 8, 2014Date of Patent: December 11, 2018Assignee: SanofiInventors: Stefan Bayer, Daniel Berning, Philippe Blank, Wolfgang Pelzer, Björn Wilden
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Patent number: 10149948Abstract: A driving and dosing device for an injection device includes: a housing, a dosing element gripped by a user, an actuating element actuable by the user to discharge the set dose, a propulsion element for acting on a piston to discharge the set dose, a spring configured to act between the propulsion element and an abutment, which is preloaded so as to discharge a maximum dischargeable product quantity in a plurality of individual discharges, a rotation element configured to rotate relative to the housing and a clutch configured for releasably engaging the rotation element. Releasing the clutch permits the rotation element to rotate relative to the housing when the actuating element is actuated, blocks the rotation of the rotation element relative to the housing when the actuating element is released, and by rotation of the rotation element, the spring is permitted to move the propulsion element in the discharge direction.Type: GrantFiled: September 30, 2014Date of Patent: December 11, 2018Assignee: TECPHARMA LICENSING AGInventors: Susanne Schenker, Ursina Streit
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Patent number: 10149949Abstract: Devices having male connectors for preventing connection to non-compatible female connectors are described. An exemplary male connector includes an elongate tip and a collar disposed coaxially around the elongate tip including a plurality of ribs disposed on either an inside surface or an outside surface of the collar for preventing entry of a non-compatible female connector into a channel formed between the elongate tip and the collar. One or more embodiments pertain to a device with a male connector and a compatible female connector including a threaded portion for engaging a corresponding threaded portion of the male connector.Type: GrantFiled: August 8, 2016Date of Patent: December 11, 2018Assignee: Becton, Dickinson and CompanyInventors: Girum Yemane Tekeste, Richard Giddes
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Patent number: 10149950Abstract: The invention relates to a small-volume nebulizer that is pre-filled with at least one unit-dose of medicine and hermetically sealed until use. The nebulizer may be sealed at the top with a removable cap that may be detached at the time of use and replaced with a patient connector. Likewise, the nebulizer may be sealed at the bottom with a bottom cap that is replaced with a gas source at the beginning of a therapeutic aerosol treatment.Type: GrantFiled: November 17, 2017Date of Patent: December 11, 2018Assignee: Caddo Medical Technologies LLCInventor: Joseph Dee Faram
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Patent number: 10149951Abstract: A piercing device for use in internally pierced blister delivery devices include a base, a piercer body and an internal fluid path. The internal fluid path includes one or more inlet channels into a central cavity which is connected to one or more delivery channels and exit ports. The cavity is defined by angular walls and top to create turbulence in the fluid flow and to produce a controllable spray, mist, drops, plume or stream delivery. The piercer body also provides a pointed lancet disposed in the center of the exit ports for piercing the lidstock of a formed blister.Type: GrantFiled: October 15, 2014Date of Patent: December 11, 2018Assignee: Mystic Pharmaceuticals, Inc.Inventors: Jesse Ryan Hancock, Michael Shaw
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Patent number: 10149952Abstract: A continuous positive airway pressure (CPAP) device to non-invasively treat a sleep disordered breathing disorder of a user may include a humidifier indicator backlight configured to indicate operation of a humidifier and a heated tube, the humidifier indicator backlight having an on state and an off state, a first backlit color and a second backlit color, and a first brightness and a second brightness, and the humidifier indicator backlight being configured to change between the first backlit color and the second backlit color and/or between the first brightness and the second brightness in response to user adjustment of a humidifier setting and/or a heated tube setting.Type: GrantFiled: June 1, 2015Date of Patent: December 11, 2018Assignee: RESMED LIMITEDInventors: Mark Bertinetti, David Peter Wawrzonek, Phoebe Katherine Hill, Rohan Neil Primrose, Heike Thiele, Alexander Virr, Andrew Roderick Bath, Sandra Robyn Curtis, Andrew Mikael Price
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Patent number: 10149953Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.Type: GrantFiled: August 31, 2011Date of Patent: December 11, 2018Assignee: Fisher & Paykel Healthcare LimitedInventors: Jonathan Mark Church, Simon Boulton, David Robert Kemps
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Patent number: 10149954Abstract: A kit including a device which provides breathable gas to a patient and a specific facing, the device including a unit which provides a flow of breathable gas, a processor which drives the unit, and a receiving region which receives the specific facing. The unit and the processor provide the breathable gas in at least two different modes of operation, and a specific mode of operation can be selected out of the at least two modes by attaching the specific facing onto the receiving region.Type: GrantFiled: March 11, 2014Date of Patent: December 11, 2018Assignee: RESMED LIMITEDInventors: Bernd Christoph Lang, Andreas Kirchberger, Johannes Nickol, Achim Biener, Jens Rothfuss, Johann Sebastian Burz, Robert Eibl, Christian Bayer, Craig Harris
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Patent number: 10149955Abstract: A laryngeal mask for use in a patient includes an airway tube having an inner lumen and a distal end; and a mask portion connected at a proximal end thereof to the distal end of the airway tube and having a distal tip opposite the proximal end. The mask portion includes an inflatable cuff including an anterior cuff surface configured to contact the patient's tissue when the inflatable cuff is inflated; and a wedge portion including a stabilization surface and two walls connected to the inflatable cuff and extending therefrom toward the stabilization surface, the stabilization surface extending from the distal tip of the mask portion toward the distal end of the airway tube at a wedge angle of between about 12 and 30 degrees, the wedge angle formed between the stabilization surface and the anterior cuff surface when the inflatable mask is inflated, whereby the stabilization surface is transversely and longitudinally substantially flat to stabilize the laryngeal mask in use.Type: GrantFiled: December 18, 2015Date of Patent: December 11, 2018Assignee: AMBU A/SInventors: Jan Guldberg Hansen, Troels Nicolaj Qvist, Peer Hoffmann, Erik Øllgaard Vilhelmsen, Lasse Kjeld Gjøske Petersen
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Patent number: 10149956Abstract: A bi-lateral endobronchial suctioning device includes actuating and articulating components that allow a provider to accurately suction both right and left bronchi as well as the trachea in a controlled and safe manner. A control mechanism is used to manipulate the actuating components in tubes forming a suction catheter to flex the tip of the bi-lateral endobronchial suctioning device to the left and to the right when the device is inserted through an endotracheal tube or other similar device, to enable directional control of a catheter for suctioning the lungs or trachea. The device further includes a bronchoalveolar lavage (BAL) port allowing sterile saline or other liquids or fluids to travel down the catheter lumen to assist with breaking up thick secretions which collect in the airways.Type: GrantFiled: February 28, 2015Date of Patent: December 11, 2018Inventors: John P. Ure, Richard S. Teames
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Patent number: 10149957Abstract: A tracheal intubation system including a laryngoscope is disclosed. An endotracheal tube exchange system is also disclosed. In some examples, the system includes a laryngoscope, a stylet, and an endotracheal tube. In some examples the stylet is an articulating stylet. An endotracheal tube with one or more depth-assessment bands is also disclosed. An articulating stylet with one or more depth-assessment bands and an orientation mark is also disclosed. A method of positioning an endotracheal tube in a patient is also disclosed. A method of positioning a stylet for placement of an endotracheal tube is also disclosed. A method of performing an endotracheal tube exchange procedure is also disclosed.Type: GrantFiled: September 23, 2014Date of Patent: December 11, 2018Assignee: University of Utah Research FoundationInventor: Sean T. Runnels
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Patent number: 10149958Abstract: A reality system includes a display aimed at a retina, the display providing 3D images with different depth view points; a variable reflectance mirror to selectably turn on or off view of an outside environment in front of the person's eye; a processor coupled to the camera and to the variable reflectance mirror to selectably switch between augmented reality and virtual reality; and a wireless transceiver coupled to the transceiver to communicate with a remote processor.Type: GrantFiled: May 6, 2016Date of Patent: December 11, 2018Inventors: Bao Tran, Ha Tran
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Patent number: 10149959Abstract: A night light with integrated water features is provided. Changing audial frequencies are generated by the cavitation bubbles in the lower chamber and simulate the tranquil, calming effects of gently tumbling waves on a beach. The cavitation bubbles also sparkle with color when illuminated by lighting below the lower chamber, providing substantial augmentation of the visual display. Colorful beads in the bead chamber are propelled in graceful random multidirectional movements, simulating the unpredictable movements of fish. Thus, the night lamp with integrated water features may serve as a maintenance free surrogate fish bowl.Type: GrantFiled: September 26, 2017Date of Patent: December 11, 2018Inventor: Anthony A. Cibulski
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Patent number: 10149960Abstract: A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of the medical tube. Also desirably, the loop presents a substantially unobstructed pathway therethrough for the flow of material from a location in the medical tube distal to the loop to a location in the medical tube proximal to the loop regardless whether the clearance member is being translated or is at rest in the medical tube. Methods of utilizing such a device are also disclosed.Type: GrantFiled: January 19, 2015Date of Patent: December 11, 2018Assignee: CLEARFLOW, INC.Inventors: Edward M. Boyle, Jr., Nathan J. Dale, Paul C. Leonard, Alan Marc Gillinov, Sam Kiderman, William E. Cohn
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Patent number: 10149961Abstract: A catheter includes an elongate member (12) having a proximal end and a distal end. The distal end has at least one drainage opening (20). At least one of; the at least one drainage opening (20) is a single elongate opening, or is two circumferentially spaced elongate openings (FIG. 5), or is at least three staggered openings (FIG. 3), or is an array of staggered openings (FIG. 3). Alternatively or additionally, a sleeve member (10) is arranged on the elongate member (12) and is movable at least between a first position (FIG. 1) covering the at least one drainage opening (20) and a second position (FIG. 2) which allows fluid to pass into the catheter. A method of using the catheter includes inserting a catheter having a retractable sleeve (10) into a user's body and retracting the retractable sleeve (10) to expose drainage openings (20) and drain fluid from the body.Type: GrantFiled: August 28, 2009Date of Patent: December 11, 2018Assignee: C. R. Bard, Inc.Inventor: Steven Carleo
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Patent number: 10149962Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.Type: GrantFiled: March 18, 2016Date of Patent: December 11, 2018Assignee: Prytime Medical Devices, Inc.Inventors: Curtis J. Franklin, David Spencer, Todd J. Krummenacher
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Patent number: 10149963Abstract: Devices and methods are provided to conduct fluid away from or deliver fluid to an area of a treatment site of a patient's body. In one aspect of the invention, a catheter includes a terminal end with a fluid exchange portion. The terminal end may further include a diffuser. The terminal end may further include a barrier.Type: GrantFiled: January 4, 2016Date of Patent: December 11, 2018Assignee: Vital 5, LLCInventors: Thomas Wade Fallin, Jean-Sebastien Merette, Patrick Michel White
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Patent number: 10149964Abstract: An easily removable, non-irritating stretchable sleeve or chest wrap for protecting and securing a PICC line or chest catheter tubing and cap extending externally from the insertion point. The sleeve or chest wrap is easily attached to a patient's arm or body, securing the small length of the external PICC line or the central venous catheter, protecting the tubing and cap from external contaminants, and allowing easy access to the PICC line or the central venous catheter for administration of drugs or nutrients, and access for blood draws. This sleeve allows the patient freedom of movement and is comfortable enough to prevent skin irritation over long-term usage.Type: GrantFiled: July 10, 2012Date of Patent: December 11, 2018Inventors: Michael Fitzgerald, Kezia Fitzgerald
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Patent number: 10149965Abstract: A guide wire is described for navigating body channels such as vessels. The guide wire can include an elongated member having a proximal portion and a distal portion, and a fluid passage to transport a fluid from the proximal portion to the distal portion. The distal portion of the elongated member can include a shape memory material with two way memory effect. The shape memory material can have a transition temperature less than a body temperature such that the distal portion has a first shape at the body temperature and a second shape different from the first shape at a temperature less than the transition temperature.Type: GrantFiled: July 8, 2014Date of Patent: December 11, 2018Assignee: COOK MEDICAL TECHNOLOGIES LLCInventor: Himanshu Suri
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Patent number: 10149966Abstract: A reduced pressure treatment system includes a liquid-collection canister for collecting liquid from a tissue site to which reduced pressure treatment is applied. The canister includes a first space configured to collect the liquid from the tissue site and a filter having a frame and a non-planar filter element. The filter defines a second space within the canister separated from the first space by the filter element. The filter element substantially prevents liquid from passing from the first space into the second space. The filter element substantially allows gaseous communication between the first space and the second space when the second space is exposed to a reduced pressure.Type: GrantFiled: November 11, 2015Date of Patent: December 11, 2018Assignee: KCI Licensing, Inc.Inventors: Christopher Brian Locke, Aidan Marcus Tout, Benjamin Andrew Pratt
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Patent number: 10149967Abstract: Today's suppositories are typically packaged individually for digital administration into the anal canal of a patient. A suppository applicator described herein, which works with individually packaged suppositories, can alternatively be shipped in a prepackaged operational arrangement with a suppository to enable the patient to administer the suppository through use of the applicator in a single operation after opening a hygienic wrapper containing the applicator-suppository combination. A method for manufacturing a suppository includes manufacturing the suppository in the presence of and in contact with an element configured to be used to insert the suppository into a body cavity. The method may include using the element to define a shape of the suppository during the manufacturing.Type: GrantFiled: October 18, 2013Date of Patent: December 11, 2018Assignee: Cristcot LLCInventors: Jennifer J. Davagian, Mark C. Ensign
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Patent number: 10149968Abstract: A method for treating a subject diagnosed with a cancer or other disorder comprising a hyperproliferative tissue is described herein. The method includes localized delivery of a material which contains a therapeutically effective agent and/or moiety. The localized delivery of the agent is achieved using a catheter-based delivery system and an implant. An implant can include a support component, a cover component, and a valve component. The valve component can be operable to permit flow through the implant. The implant can be delivered on a catheter, with one of the ends of the implant being selectively expanded to permit temporary occlusion of a vessel while delivering a material through the valve component to a downstream target region. The other end of the implant can thereafter be released such that the implant occludes the vessel, or the implant can be removed from the vessel entirely.Type: GrantFiled: December 17, 2015Date of Patent: December 11, 2018Assignee: ArtVentive Medical Group, Inc.Inventor: Leon Rudakov
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Patent number: 10149969Abstract: The appliance includes an appliance body/handle and an interface assembly for receiving a detachable workpiece. The body/handle includes a signal-generating assembly with electrical connections to the appliance body interface. The signal-generating assembly is controlled by a microprocessor, which generates signals adapted to control and operate the workpiece which is attached to the appliance. A plurality of workpieces are included which are individually adapted for treating various spot skin irregularities. The appliance further includes a system for identifying the workpiece attached, so that appropriate operating signals can be generated and provided to the attached workpiece.Type: GrantFiled: September 25, 2014Date of Patent: December 11, 2018Assignee: L'OréalInventors: Joseph Grez, Zane Miller, Scott Straka, James Christopher McInnes
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Patent number: 10149970Abstract: A method for delivering liquid into the pores of recipient human skin is provided. The method comprises delivering, via a nozzle, at least one stream of the liquid under pressure to the pores, the stream having a cross-section with a diameter no greater than about 50 ?m, applying a negative pressure across an area of the skin being treated, rotating the nozzle relative to the area at a speed up to about 200 revolutions per minute, contacting an electrode connected to a first terminal of a power source, having a first electric charge, to the skin, and contacting a second terminal of the power source, having a second electric charge, opposite the first electric charge, to the liquid, thereby imparting an electrical current between about 0.2 mA and 0.3 mA to the skin in the vicinity of the pores. The delivering, applying, rotating, and contactings occur simultaneously.Type: GrantFiled: September 7, 2014Date of Patent: December 11, 2018Inventor: Michael Tavger
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Patent number: 10149971Abstract: Various embodiments of an antimicrobial stopcock medical connector is provided. More specifically, the present invention relates to a stopcock tap having fluid channels provided on portions of the outer surface of the stopcock tap, whereby fluid bypasses the stopcock through the fluid channels by flowing between the outer surface of the stopcock tap and the inner surface of the stopcock housing. Some embodiments further comprise an antimicrobial coating or insert that is provided in the one or more fluid channel, whereby fluid flowing through the fluid channels contacts the antimicrobial coating or an antimicrobial agent that is eluted from the antimicrobial coating. Further still, some embodiments of the present invention comprise an antimicrobial groove that is positioned opposite the fluid channel, whereby when the stopcock is in an “off” position, the antimicrobial groove contacts fluid within a blocked port thereby preventing microbial growth therein.Type: GrantFiled: April 23, 2014Date of Patent: December 11, 2018Assignee: Becton, Dickinson and CompanyInventors: Huibin Liu, Bryan Fred Bihlmaier, Janice Lin
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Patent number: 10149972Abstract: An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a first plurality of electrically isolated electrodes called field-shaping electrodes that are located under the surface of the supporting structure, and a second plurality of ordinary electrically stimulating electrodes called active electrodes, that are located at the surface of the supporting structure, capable of injecting electric charges in the space surrounding the supporting structure. Both types of electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field, which has consequence on the path of the stimulating currents injected by active electrodes.Type: GrantFiled: February 9, 2016Date of Patent: December 11, 2018Inventor: Sergio Lara Pereira Monteiro
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Patent number: 10149973Abstract: A multipart, non-uniform patient contact interface and method of use are disclosed.Type: GrantFiled: June 12, 2014Date of Patent: December 11, 2018Assignee: CARDIOTHRIVE, INC.Inventors: Douglas M. Raymond, Peter D. Gray, Walter T. Savage, Shelley J. Savage
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Patent number: 10149974Abstract: A sub-epidermal electric warning device has electrodes penetrating through the patient's epidermis and bipolar electric warning signals are transmitted to the sub-epidermal tissue by these electrodes. A device for surveillance of vital signs, analyte levels, or treatment parameters is using a sub-epidermal electric warning device for notifying the patient in situations requiring intervention.Type: GrantFiled: June 12, 2013Date of Patent: December 11, 2018Assignee: PHARMASENS AGInventors: Paul Hadvary, Hansjorg Tschirky, Rudolf Dinger, Jean-Pierre Michot
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Patent number: 10149975Abstract: A transcutaneous electronic nerve stimulation device configured to provide therapy to a patient includes a control unit assembly, a power source, and a therapy plate electrically coupled to the power source. The therapy plate includes an electrical source configured to deliver electrical stimulation to the patient, a heat source configured to deliver heat to the patient, and a radiation source configured to deliver radiation to the patient. The transcutaneous electronic nerve stimulation device further includes a rigid connector electrically coupling the therapy plate to the power source such that the therapy plate is fixed relative to the power source.Type: GrantFiled: March 1, 2016Date of Patent: December 11, 2018Assignee: EASYWELL BIOMEDICALS, INC.Inventor: Cheng-Lin Chuang
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Patent number: 10149976Abstract: A method for implanting a wireless neural stimulator device, the method including: making a surgical incision or a percutaneous opening on a patient's skin; inserting an assembly of an introducer or needle and a needle stylet through the surgical incision or a percutaneous opening and underneath the patient's skin, the needle stylet mounted in an inner lumen of the introducer or needle; withdrawing the needle stylet from the inner lumen of the introducer or needle when the assembly is in place; inserting the wireless neural stimulator device through an inner lumen of the introducer or needle and into the patient's tissue; and withdrawing the introducer from the surgical incision or percutaneous opening.Type: GrantFiled: March 7, 2016Date of Patent: December 11, 2018Assignee: Micron Devices LLCInventors: Chad David Andresen, Laura Tyler Perryman
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Patent number: 10149977Abstract: Spinal cord stimulation (SCS) system having a recharging system with self-alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsource, and IPG control through software on Smartphone/mobile device and tablet hardware during trial and permanent implants. SCS system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) providing concurrent, but unique stimulation fields. SCS system can include a replenishable power source, rechargeable using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery, can charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. A bi-directional telemetry link informs the patient or clinician the status of the system, including the state of charge of the IPG battery.Type: GrantFiled: September 30, 2016Date of Patent: December 11, 2018Assignee: Cirtec Medical Corp.Inventors: Saif Khalil, Raghavendra Angara, Miles Curtis, Christopher Biele, Daniel Fellmeth
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Patent number: 10149978Abstract: Short pulse width spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, modulation signal has pulse widths in the range of from about 10 microseconds to about 50 microseconds may be applied to the patient's spinal cord region to address chronic pain without using paresthesia or tingling to mask or cover the patient's sensation of pain. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.Type: GrantFiled: November 6, 2014Date of Patent: December 11, 2018Assignee: Nevro Corp.Inventor: Sangsoo Wesley Park
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Patent number: 10149979Abstract: Techniques for determining the location of a physiological midline are disclosed. A first technique evaluates the response to stimulation of spinal electrodes at peripheral electrodes on different sides of the body. In this technique, a spinal electrode's position relative to a physiological midline is determined based on a relationship between responses to its stimulation observed on different sides of the body. A second technique evaluates the response of spinal electrodes to stimulation of peripheral electrodes on different sides of the body. In this technique, a spinal electrode's position relative to a physiological midline is determined based on the different responses that it observes to stimulation on different sides of the body.Type: GrantFiled: March 23, 2017Date of Patent: December 11, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Raul Serrano Carmona, Bradley Hershey
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Patent number: 10149980Abstract: A high density electrical connector system is disclosed which may make use of first and second connector components. The first connector component has a first substrate with a first plurality of electrical feedthroughs and at least a first plurality of electrically conductive bond pads in communication with the first plurality of electrical feedthroughs. The second connector component has a second substrate with a second plurality of electrical feedthroughs and at least a second plurality of electrically conductive bond pads in communication with the second plurality of electrical feedthroughs. An electrical coupling subsystem is disposed between the first and second connector components and makes electrical contact between associated pairs of the first and second pluralities of electrically conductive bond pads. A plurality of fasteners may be used for clamping the first and second connector components in facing relationship.Type: GrantFiled: June 24, 2015Date of Patent: December 11, 2018Assignee: Lawrence Livermore National Security, LLCInventors: Kedar G. Shah, Satinderpall S. Pannu, Susant Patra
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Patent number: 10149981Abstract: The current technology relates to a shock deferral unit that is portable by an ambulatory patient. The shock deferral unit has a bi-directional communication device configured to receive a notification of an impending shock from a defibrillator and configured to send an instruction to defer the impending shock to the defibrillator. An authentication interface is configured to receive authentication data from a user. A user instruction interface is configured to receive the instruction to defer the impending shock from the user. An authentication device is configured to authenticate the user based on the authentication data and instruct the bi-directional communication device to send the instruction to defer a shock upon authentication and receipt of the instruction to defer the shock.Type: GrantFiled: May 2, 2017Date of Patent: December 11, 2018Assignee: Cardiac Pacemakers, Inc.Inventors: Jeffrey E. Stahmann, Dan C. Goldman
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Patent number: 10149982Abstract: A method of treating and preventing a neurological disorder, such as Alzheimer's disease, in a subject in need thereof by positioning an electromagnetic field emitting source proximal to the subject and exposing the subject to an electromagnetic field having a predetermined frequency (preferably ?300-3,000 MHz) for a predetermined absorption period (preferably greater than ?3 days). Each individual treatment (comprising exposure to the predetermined frequency for the predetermined absorption period) is continued at a predetermined schedule for a predetermined treatment period. The EMF can have a specific absorption rate up to about 8 W/kg. The methodology enhances cognition in the subject and/or treats/prevents the underlying neurological disorder or a symptom thereof.Type: GrantFiled: December 21, 2015Date of Patent: December 11, 2018Assignees: University of South Florida, The United States of America as represented by the Department of Veterans AffairsInventors: Gary W. Arendash, Chuanhai Cao, Jun Tan
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Patent number: 10149983Abstract: A tanning or a phototherapy system including a light source including light emitting elements configured to emit ultraviolet (UV) light having different peak wavelengths, a controller configured to control luminous characteristics of the light source, and a sensor configured to sense at least one of the luminous characteristics of the light source and a user's skin condition, in which the luminous characteristics of the light source are controlled by the controller based on the user's skin condition sensed by the sensor, and controlling the luminous characteristics comprises increasing or decreasing luminous intensity of one or more of the light emitting elements.Type: GrantFiled: June 20, 2016Date of Patent: December 11, 2018Assignees: Seoul Viosys Co., Ltd., Sensor Electronic Technology, Inc.Inventors: Emmanuel Lakios, Max Shatalov, Timothy Bettles, Alex Dobrinsky
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Patent number: 10149984Abstract: The system for treating a region of the epidermis, comprising: —at least one laser energy source; —a time control device to generate a laser beam; —a laser energy focusing system arranged and produced to direct a laser beam on said region of the epidermis. The control device generates a laser beam comprising a plurality of composite pulses, emitted at a base frequency, each composite pulse comprising a sequence of sub-pulses at a higher frequency than said base frequency.Type: GrantFiled: February 9, 2012Date of Patent: December 11, 2018Assignee: EL.EN. S.P.A.Inventors: Stefano Modi, Maurizio Scortecci, Damiano Fortuna, Tiziano Zingoni, Leonardo Masotti, Gabriele Clementi, Nicola Zerbinati
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Patent number: 10149985Abstract: There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.Type: GrantFiled: May 24, 2016Date of Patent: December 11, 2018Assignee: KLOX TECHNOLOGIES INC.Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
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Patent number: 10149986Abstract: The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular properties such as vascular tone, arterial diameter, and vascular growth.Type: GrantFiled: June 26, 2017Date of Patent: December 11, 2018Assignees: Brown University, Massachusetts Institute of TechnologyInventors: Tyler C. Brown, Christopher I. Moore
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Patent number: 10149987Abstract: A method for generating synthetic electron density information based on an acquired magnetic resonance, MR, image stack is disclosed.Type: GrantFiled: May 4, 2015Date of Patent: December 11, 2018Assignee: SPECTRONIC ABInventor: Carl Siversson
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Patent number: 10149988Abstract: An x-ray apparatus includes a source configured to generate electrons, a target configured to produce x-rays upon impingement of electrons, and a detector configured to detect electrons penetrating the target or reflected from the incident face of the target, indicative of damage to the target.Type: GrantFiled: March 18, 2016Date of Patent: December 11, 2018Assignee: Varian Medical Systems, Inc.Inventor: Raymond D. McIntyre