Abstract: A system for monitoring and detecting the gait and other health related parameters of a user. One such parameter is monitoring of medication compliance and treatment session attendance done by a medication and liquid dispensing apparatus, which combines mechanical dispensing of medication. These parameters are provided in standard of care summaries to care providers, and are continually reported by the Optimum Recognition Blueprint as Standard of Care Summaries to care providers, as well as communicated to the end-user by the Virtual Caregiver Interface.

Abstract: One aspect of the present disclosure relates to a physical training system for injury prevention and rehabilitation. The training system can include a wearable device in communication with an external device, which can be used to train at least the athlete wearing the wearable device. The wearable device can reduce the number of sensors needed to capture motion data required for the training. For example, the wearable device can include an inertial measurement unit (IMU) device located at a position relative to a joint of an athlete to measure an inertial displacement of the joint and an optical sensor to measure an angle of the joint. The wearable device can include a wireless transceiver to communicate a characteristic of motion of the joint (determined based on data from the IMU and the optical sensor) to an external device.

Abstract: A method of analysing breathing data representing a shape of the trunk of a subject 104 as a function of time to monitor and/or analyse the subject's breathing pattern. The data is measured and processed into a data array relating to a 2-dimensional grid having grid points, a position in space of the shape at each grid point and points of time. The method includes the steps of mapping the data array onto a 2-dimensional array, decomposing the 2-dimensional array and forming a signature of the subject 104 from the decomposed 2-dimensional array representing a motion pattern.

Abstract: An optosensor includes an optoreflector (1) having a light emitting element (12) and a light receiving element (13) which are mounted on a substrate (11), a light transmitting resin (15) sealing the light emitting element (12) and the light receiving element (13), and a light blocking resin (2), and optionally further includes a light transmitting cover (20) that is disposed to face a light emitting/receiving portion of the optoreflector (1). In the optosensor, a light blocking wall (2a) and an eave (2b) are formed between the light emitting element (12) and the light receiving element (13) with the light blocking resin (2), the cave (2b) being linked to the light blocking wall (2a) to narrow an upper light emitting surface of the light emitting element (12).

Abstract: Disclosed is a system which adds biochemical sensitivity to a standard biopsy needle such that the practitioner is provided immediate feedback on the metabolism and physiology of tissue in the local environment. Disclosed is a sensor integrated biopsy device for in situ and real time tissue analysis. The sensor integrated biopsy (SIB) needle system will enable biopsy teams to measure local tissue biochemistry in real time during biopsy procedures, adding a valuable new set of parameters to augment and extend conventional image-guided procedures.

Abstract: 3D microscale metamaterial structures and methods of making. The metamaterial structure includes a polygonal structure having a plurality of panels connected to one another at structure corners. A metal resonator pattern is provided on each of the panels. The resonator patterns of neighboring panels are electromagnetically coupled to one another across a gap between the resonator patterns at the corresponding structure corner. The panels can be a polymer material, layers of graphene oxide, etc. The metamaterial structure can be a 3D octagram split-ring resonator, and is completely isotropic. The 3D metamaterial structure can be made by a self-folding process.

Abstract: A system and method for measuring an amount of blood and/or clotting in a pocket around an implantable device. The system may include a first light source configured to emit light over a first wavelength range. The system may include a first photodetector configured to output a first signal indicative of an amount of the first light received by the first photodetector. The system may include the implantable device and an external device. The implantable device may include one of the first light source and the first photodetector, and the external device may include the other of the first light source and the first photodetector. In some embodiments, the external device may include a controller configured to calculate the amount of blood/or clotting in the pocket around the implantable device using at least a measurement of the first signal.

Abstract: A method and transceiver for calibrating an analyte sensor using one or more reference measurements. In some embodiments, the method may include receiving a first reference analyte measurement (RM1) and determining whether the RM1 is unexpected. In some embodiments, the method may include, if the RM1 was determined to be unexpected, receiving a second reference analyte measurement (RM2). In some embodiments, the method may include determining whether one or more of the RM1 and the RM2 are acceptable as calibration points. In some embodiments, the method may include, if one or more of the RM1 and the RM2 are determined to be acceptable as calibration points, accepting one or more of the RM1 and the RM2 as calibration points. In some embodiments, the method may include calibrating the analyte sensor using at least one or more of the RM1 and the RM2 as calibration points.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A photometry device can include a first LED to emit light to a target in response to a first current through the first LED, a second LED to emit light to the target in response to a second current through the second LED, and an inductor, coupled to the first and second LEDs, to store energy associated with at least one of the first and second currents.

Abstract: There is provided an injector having an improvement in a linear launching profile. The injector of the present invention is used for launching a lancet to provide a pricking. The injector of the present invention comprises a plunger capable of launching the lancet in a pricking direction, an injector housing which surrounds the plunger, and an injector cap capable of being attached and detached with respect to the injector housing. In particular, an inner face of the injector cap is provided with a rib, and the rib and the plunger moving for the pricking are capable of contacting with each other.

Abstract: A cord blood collection system is provided. The system includes a housing having an upper portion and a lower portion, the upper portion and lower portion defining a hollow interior. A peristaltic pump is disposed within the lower portion, the peristaltic pump having an input portion and an output portion. A reel member is disposed in the upper portion. A tubing member is movably coupled to the reel member, the tubing member being operably coupled to the peristaltic pump, the first end being configured to couple with a container, the second end being configured to couple with a needle.

Abstract: Provided herein are wearable and/or portable devices for the detection of at least one analyte in a body fluid. In accordance with certain aspects of the present invention, there are also provided methods for the use of invention devices for the automated administration of essential vitamins, minerals or other nutrients to a subject in need thereof. In accordance with the present invention, there are also provided body fluid sampling devices. In certain aspects of the present invention, there are also provided wearable and/or portable devices for the detection of at least one analyte in a body fluid, and the automated administration of essential vitamins, minerals or other nutrients to a subject determined to be in need thereof based on the results provided by the means for detection.

Abstract: Fluid collection/injection device comprises a body having a front end, a back end, and a main hollow section arranged between the front and back ends and a needle hub securing section arranged on the front end and being structured and arranged to receive therein a needle member. The fluid collection/injection device is structured and arranged to utilize at least an operational mode, an operational mode, and a post-use mode. In the installation mode, the needle member is coupled to the body via the needle hub securing section. In the operational mode, fluid passes through the needle member and into or out of a receptacle inserted into the main hollow section.

Abstract: A needle guard (10) has an elongate concave channel member (22) having a longitudinally extending opening between two longitudinally extending sides (30) and defining part of a passageway (36) having a forward end (40) and a rear end (64). A tongue member (24), in an open position, extends longitudinally adjacent the opening and defines at least one slot (34) between itself and at least one of the sides (30) adapted to receive at least one wing of a winged needle block. The tongue member (24) is movable to a closed position to lie within the channel member (22) to close, block or substantially close or block the passageway (36).

Abstract: One aspect of the invention provides an autonomous continuous bladder irrigation device including: a color sensor programmed to detect a color of outflow from a catheter; an occlusion unit programmed to adjustably occlude a lumen providing irrigation to the catheter; and a controller in communication with the color sensor and the occlusion unit and programmed to control the occlusion unit to titrate irrigation flow to the catheter based on the color detected by the color sensor in order achieve a specified color of outflow from the catheter.

Abstract: A method and apparatus for whole-mind cognitive interface. Such a system includes a bodily-integrated artificial cranium, computer, RF antenna, and transceiver array to seamlessly augment the human brain with artificial intelligence (AI) and permit enhanced cognitive functions, and human host feed-back-based neurological rewiring.

Abstract: A brain interaction apparatus is provided. The apparatus comprises a plurality of filaments; and a brain invasive launcher having a plurality of launching channels extending in a longitudinal direction between a proximal end and a distal end thereof. Each launching channel is configured for holding one of the plurality of filaments moveably arranged therein. At least one of the plurality of filaments is provided with a steering tip affixed to a distal end thereof. The steering tip comprises a portion tapering in a longitudinal direction of the at least one of the plurality of filaments thereby narrowing toward a distal end of the steering tip. The tapered portion is rotationally asymmetrical about a longitudinal axis of the at least one of the plurality of filaments.

Abstract: A system and method for the assessment and therapeutic treatment of neurologic function deficits through the evaluation of voluntary and involuntary neuromuscular activity and voluntary neuromuscular responses made on demand as a response to a cognitive skills test. The system permits the remote assessment and therapy of a patient through prescribed physical and cognitive skills regimens either through the remote direction of a therapist or through an artificial intelligence system that selects and modifies regimens based upon the analysis of historical data and/or real-time data. The combination of physical and cognitive therapy to require physical responses to cognitive queries is believed to improve patient outcomes by slowing, halting, or reversing the progression of certain neurological deficits.

Abstract: Embodiments of the present invention provide systems and methods for analyzing cognitive status. The method includes capturing a set of observables for a subject based on their interaction with smart objects, such as smart blocks or smart items. The method further includes accessing data sets, such as medical data about cognitive function, scientific data about cognitive function, and historical data for the subject, analyzing the set of observables, and generating a report about the cognitive abilities of the subject based on the analysis.

Abstract: Embodiments of the present invention provide a circuit board enclosed in an encasing with processors and memory, configured to receive and analyze data, and containing computer logic capable of receiving and analyzing data.

Abstract: Embodiments of the present invention provide systems and methods for analyzing cognitive status. The method includes capturing a set of observables for a subject based on their interaction with smart objects, such as smart blocks or smart items. The method further includes accessing data sets, such as medical data about cognitive function, scientific data about cognitive function, and historical data for the subject, analyzing the set of observables, and generating a report about the cognitive abilities of the subject based on the analysis.

Abstract: This disclosure provides methods, reagents, and diagnostic and prognostic markers useful for non-invasive identification, diagnosis, and therapeutic intervention in individuals with epilepsy. More particularly, the disclosure uses specific metabolites measured by magnetic resonance spectroscopy in brain tissue to detect epileptic brain regions.

Abstract: The present invention relates to a wearable device for determining electro-dermal activity of a subject (1). The device (10) comprises a light source (11) for emitting light including infrared light in the wavelength range between 750 and 950 nm into tissue of the subject, a light sensor (12) for receiving at least part of the emitted light after an interaction of the emitted light with the tissue, an evaluation unit (13) for determining the electro-dermal activity from the received light, and a support (14) for carrying the light source (11), the light sensor (12) and the evaluation unit (13), wherein the light source and the light sensor are arranged at a predetermined distance from each other.

Abstract: The invention concerns wearable electronic devices, systems and methods for sports performance monitoring. In one embodiment, the invention provides a device comprising a heartbeat sensor for providing a heartbeat signal, a motion sensor for providing a motion signal and processing means adapted to calculate at least one performance parameter depicting said sports performance and/or the person using temporal characteristics of periodic features of the heartbeat signal compared with temporal characteristics of periodic features in the motion signal. The invention allows for utilization of an existing relation between cadence and heart rate for characterizing the performance or the person in a novel way.

Abstract: A method of and apparatus for processing optical coherence tomography (OCT) scans through a subject's skin (7), the method comprising: receiving at least one OCT scan through the subject's skin (7), each scan representing an OCT signal in a slice through the subject's skin; processing each OCT scan so as to determine the presence of at least one blood vessel (9) in each scan; determining a diameter of at least one of the at least one blood vessels (9) whose presence has been determined; and typically determining a depth profile of blood vessel density for different vessel diameters.

Abstract: The present disclosure pertains to a system configured to determine sleep stages in a subject based on cardiac artifact information and brain activity information in EEG signals. Cardiac artifacts present in EEG signals can cause erroneous sleep stage determinations which may result in inopportune sensory stimulation during sleep, no stimulation at all, discarding long periods of EEG signal information, and/or other events. The present system enhances real-time sleep stage determinations compared to prior art systems and/or provides other advantages because the present system determines the current sleep stage of the subject based on both cardiac activity information and brain activity information included in the EEG signals.

Abstract: Peripheral oedema causes a swelling of the legs of a patient due to an abnormal accumulation of fluids in the interstitium of the patient. Oedema is directly related to heart diseases, kidney and liver problems and pathological conditions. As such, is a useful indicator of a person's overall health. Oedema is typically assessed by a subjective manual test administered by a medical professional. As such, an objective assessment of oedema is often difficult to make. The present disclosure concerns a device for tissue condition measurement. The device enables an objective assessment of oedema to be made, by providing to a medical professional, or a medical ancillary worker, with information useful to judge the presence of oedema.

Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.

Abstract: The disclosure describes a wearable, low-cost and low-power Electrical Impedance Tomography system for gesture recognition. The system measures cross-sectional bio-impedance using electrodes on wearers' skin. Using all-pairs measurements, the interior impedance distribution is recovered, which is then fed to a hand gesture classifier. This system also solves the problem of poor accuracy of gesture recognition often observed with other gesture recognition approaches.

Abstract: An earpiece includes an earpiece housing, at least one biometric sensor disposed within the earpiece, a wireless transceiver disposed within the earpiece for voice communications, an intelligent control operatively connected to the at least one biometric sensor and the wireless transceiver, a speaker operatively connected to the intelligent control, and at least one microphone operatively connected to the intelligent control. The earpiece is configured to monitor biometrics of a user using the at least one biometric sensor, communicate biometric data to the user, detect a crisis level event, and communicate occurrence of the crisis level event using the wireless transceiver.

Abstract: A method and a system for monitoring healthcare garments (3), wherein the method comprises the steps of: providing a temperature sensor (1) on or in a healthcare garment, sensing the temperature of the healthcare garment by means of the temperature sensor, transferring temperature data relating to the sensed temperature over at least one network (5) and a wireless interface (7) from the temperature sensor to a base station (4), and based on the transferred temperature data, determining information relating to a usage cycle of said healthcare garment.

Abstract: An optical measurement device with pressure feedback function includes an optical detecting module and a stretchable connective belt. The optical detecting module is adapted to output at least one optical detecting signal to detect pressure applied on an object. The stretchable connective belt is assembled with the optical detecting module and utilized to tie the optical detecting module on the object, and the stretchable connective belt is deformed to vary the pressure generated by the optical detecting module.

Abstract: [Object] To realize a system that can more accurately analyze a movement of a body with a simpler configuration. [Solution] An information processing device includes: a first member that includes a substantially plate-shaped casing and a predetermined detection unit; a second member that includes a substantially plate-shaped casing and that holds a battery inside the second member; and a connection unit that includes an elastic body and connects a part of an outer circumferential end surface of the first member to a part of an outer circumferential end surface of the second member such that a surface direction of one surface of the first member substantially matches a surface direction of one surface of the second member. The information processing device is worn on a predetermined body part such that the one surface of the first member and the one surface of the second member are located on a side of the body part.

Abstract: A method of processing signals from an accelerated MRI scan of a dynamic event occurring in the body of a human patient. The patient is subjected to an MRI examination which includes the relevant portion of his body. Those voxels for which there is no substantially no change over the time of the scan are identified and subtracted from the overall scan signal.

Abstract: In embodiments, an external medical device is intended to care for a patient. If it receives an input that signifies that ventilation artifact is present in a signal of the patient, it transmits a corrective signal responsive to the received input. In further embodiments, a patient signal is received, which is generated from a patient while the patient is or was receiving chest compressions at a frequency Fc, and also receiving ventilations at frequency Fv. At least one filter mechanism may be applied to the patient signal to substantially remove artifacts at a) frequency Fc, b) a higher harmonic of frequency Fc, and c) a third frequency substantially equaling frequency Fc plus or minus frequency Fv, while substantially passing other frequencies between them. As a result, the patient signal can be cleaner, for diagnosing the patient's state more accurately.

Abstract: A system includes a sensor configured to sense physiological information from a subject, and a signal processor configured to process signals from the sensor into a serial data stream of physiological information and sensor performance information. An electronic device having a display is configured to receive the serial data stream and display the physiological information simultaneously with the sensor performance information via the display.

Abstract: The present invention relates to a device, system and method for determining a vital sign of a person. To improve accuracy and reliability of vital sign determination, the device comprises an input unit (20) for obtaining a vital sign related signal of at least a body part of the person, from which a vital sign can be derived, a body part position determining unit (21) for determining if said body part of the person is in contact with a support or not and generating a contact signal indicating if said body part is in contact with the support or not, a quality metric setting unit (22) for setting, based on said contact signal, a quality metric for use in the determination of a vital sign of the person, and a vital sign deriving unit (23) for deriving a vital sign from the obtained vital sign related signal, wherein the set quality metric is used in the derivation of the vital sign and/or in a judgment of the reliability of a derived vital.

Abstract: Provided are an electronic device, a signal processing method thereof, a biological signal measurement system, and a non-transitory computer readable recording medium. The electronic device, according to one embodiment of the present disclosure, comprises: a sensor for measuring a biological signal of a user; and a processor for determining the periodicity of the measured biological signal, and selectively compressing the measured biological signal according to the determined periodicity.

Abstract: The present invention is configured to compare an output result of frequency analysis of a frequency gradient time-series waveform of a biosignal with preset corresponding data of output results of brain waves of different biological states to the output result. Accordingly, it is possible to estimate a time-series variation of a biological state which is specified by a brain wave state and brain waves by using a biological index other than brain waves, in particular, a result of frequency analysis of a frequency gradient time-series waveform of a biosignal reflecting an autonomic nervous function. Using an electroencephalograph is not required, and thus it is possible to estimate brain waves and a biological state corresponding to brain waves easily and rapidly.

Abstract: Systems and methods for diagnosing or monitoring progress of a pathology using laser induced breakdown spectroscopy (LIBS) and machine learning are disclosed.

Abstract: Analyte sensor faults are detected. Datasets of glucose values sensor electronics are coupled to a glucose sensor in fluid contact with interstitial fluid under a skin surface. Baseline median glucose value and glucose variability values are computed, based on the first dataset. A baseline data point is stored. Evaluation median glucose value and variability are computed, based on the second dataset of glucose values. An evaluation data point is stored. A magnitude of a vector that extends between the baseline data point and the evaluation data point is computed. A component of the magnitude of the vector that is parallel to a hypoglycemia risk contour line is computed and compared to a predefined threshold value. An indication that a sensor fault has been detected if the component is greater than a threshold is displayed.

Abstract: Systems and methods of managing a plurality of patients undergoing titration using a management device. The method includes receiving, via a processor of a management device, a plurality of patient information from the plurality of patients, evaluating, via the processor of the management device, each patient based on patient information, determining, via the processor of the management device, a status of each patient, where the status is based on a progression of the titration based on titration assist parameters and determining, via the processor of the management device, a priority of each patient based on patient status. In some embodiments the method includes sorting that patients based on user input. In some embodiments, the plurality of patient information is received via remote communication with at least one of a programming device, an implantable medical device, or a home management device.

Abstract: The invention provides a system (100a) for tracking infant development, the system comprising: —a portable device (101) including a camera and a processing unit, and —a weighing scale (102), preferably comprising a wireless transceiver; wherein the weighing scale is configured to measure the weight of an infant and to transmit the measured weight information to the portable device; and wherein the portable device is configured to —capture (401) an image of the infant; —combine the received weight information and information derived from the image of the infant to obtain (404) infant development statistics; and —store (403) the image and the obtained infant development statistics in a storage; wherein the information derived from the image includes at least one of the height of the infant and the head circumference of the infant. The invention further provides a portable device, a weighing scale, and a computer readable medium.

Abstract: A method for preventing obesity related to infection by an adipogenic adenovirus includes obtaining a sample from a person, assaying the sample to determine whether the person has been previously infected with an adipogenic adenovirus, and if the person has not been previously infected, providing the person with at least one sensor positioned to detect when a person's hand approaches a predetermined distance from the person's face. By warning the person of undesired hand-to-face contacts, the person is able to reduce the incidence of obesity related infections. Other embodiments are directed to a kit for preventing obesity caused by infection with an adipogenic adenovirus, such kit including a container for assaying an agent indicating the presence of antibodies to Ad-36, and a sensor positioned on an item selected from the group consisting of one of a hat, a writing instrument, eye glasses, a belt, sunglasses, a bra, a shirt, and a tie.

Abstract: An image processing apparatus (IP) comprising an input port (IN) for receiving projection data through respective 3D locations in an imaging region, said projection date collected in a scan operation by an imaging apparatus (IM). An image segment generator (IGS) of said apparatus (IP) is configured to generate, based on said projection data, a first image segment for said 3D locations. A visualizer (VIZ) configured to effect displaying said first image segment on a display device before or whilst the image apparatus collects projection data for a different 3D location.

Abstract: An imaging apparatus and a positioning apparatus that include an imaging unit for imaging a detected part of a body to be detected; and a distance positioning unit having at least two signal positioning devices, i.e., a signal generator and a signal detector, wherein one signal positioning device is arranged at the detected part, the other signal positioning device is arranged at a position where a predetermined position relationship exists relative to the imaging unit. The position of the detected part in at least one direction in a three-dimensional space relative to the imaging unit is obtained according to a measured distance between the two signal positioning devices. The imaging apparatus and the positioning apparatus reduce pre-positioning imaging sequence workload, and the risk of radiation on the body to be detected is avoided.

Abstract: An X-ray imaging apparatus and control method for the same relate to a mobile X-ray imaging apparatus that allows a user to recognize whether the X-ray imaging apparatus is in an appropriate imaging distance from an object. The X-ray imaging apparatus includes an X-ray source, an input unit that receives distance information between the X-ray source and an X-ray detector, a reference light emitter that irradiates a light from the X-ray source in a direction where the X-ray detector is placed, at least one auxiliary light emitter that irradiates a light that overlaps with a light from the reference light emitter; and a controller that determines an auxiliary light emitter corresponding to the distance information among the at least one auxiliary light emitter, and controls the reference light emitter and the determined auxiliary light emitter so that the reference light emitter and the determined auxiliary light emitter irradiate a light.

Abstract: A method for controlling x-ray frame rate of an imaging system for a catheter procedure system includes generating a first control signal that indicates a first frame rate and providng the first control signal to an imaging system. The imaging system obtains a first set of images at the first frame rate based on the first control signal. At least one parameter of a catheter procedure performed by the catheter procedure system is determined and a second control signal is generated based on the at least one parameter of the catheter procedure. The second control signal indicates a second frame rate. The second control signal is provides to the imaging system to adjust the first frame rate to the second frame rate. The imaging system obtains a second set of images at the second frame rate and displays the second set of images on a display.