Abstract: A medical imaging system (10) including an optical branching device (101) having a plurality of optical paths for guiding light for imaging a target comprising a biotissue, each of the optical paths corresponding to an optical port connectable to an external device for imaging, wherein at least one path of the plurality of optical paths is configured both to guide the irradiation light to the biotissue and to guide light from the biotissue, and wherein the optical branching device includes a plurality of prisms and at least one joint surface.

Abstract: A device and method for cleaning or defogging a surgical scope during minimally-invasive surgery, including a casing which houses a sponge and a heating element configured to be accessible to the surgical scope and the casing is configured to removably attach to a trocar during a surgical procedure.

Abstract: An arthroscope having an elongated core with a square radial cross section.

Abstract: A supercontinuum light source can include a seed laser arranged to provide seed pulses with a pulse frequency Fseed; a pulse frequency multiplier (PFM) arranged to multiply the seed pulses by converting pulses having the pulse frequency Fseed to pump pulses with a pulse frequency Fpump, where Fpump is larger than Fseed; and a non-linear element arranged to receive said pump pulses and convert said pump pulses to pulses of supercontinuum light. The PFM can further include a splitter for splitting pulses into first and second sub beams each having the same pulse frequency, where the PFM is configured such that the sub beams experience different delays; and a combiner for combining said first and second sub beams into a beam having the pulse frequency that is greater than said same pulse frequency. The splitter can have an uneven splitter ratio. The disclosure includes other embodiments as well.

Abstract: An exemplary system, method and computer-accessible medium can be provided that can, for example, can be provided so as to receive regarding at least one portion of an ophthalmic sample(s) based on a radiation(s) provided from the sample(s). In addition, it is possible to determine whether an inflammation marker(s) is present in a portion(s) of the sample(s) based on the information. Further, an identification can be performed as to that an abnormality(s) exists in a further anatomical structure based on the determination. The further anatomical structure can be different from the sample(s).

Abstract: An ophthalmologic information processing device includes a processor and a memory that stores computer-readable instructions. The computer-readable instructions, when executed by the processor, cause the ophthalmologic information processing device to perform processes that include setting a target position on an ocular fundus of a patient's eye, determining a position of one of a ganglion cell corresponding to a photoreceptor cell present at the target position and a photoreceptor cell corresponding to a ganglion cell present at the target position, and obtaining a first analysis result of a retina at the determined position based on one of a second analysis result and a third analysis result. The second analysis result includes an analysis result of the retina at a center point of the determined position and an analysis result of the retina at an auxiliary point. The third analysis result includes an analysis result of the retina in an analysis region.

Abstract: Provided are a method and system for identifying and classifying the owner, age and health of an optic nerve head and its vasculature based on analysis of vector relationships of blood vessels and the neuroretinal rim within an image of the optic nerve head to each other.

Abstract: There is a need for robust and portable system, and apparatus for ophthalmology. We propose use of foldable ophthalmic system. Our system will have a chin-rest (or face-rest or forehead rest) that can be folded so that the ocular device could be transported in a brief-case type casing. Our system can be used for many modalities including optical coherence tomography.

Abstract: The present disclosure relates to an apparatus for angiographic optical coherence tomography in the retina or the choroid, and a method for diagnosing diseases by using the same and, more specifically, to: an apparatus for angiographic optical coherence tomography in the retina and the choroid, capable of diagnosing, at an early stage, shock states or diseases such as those of sepsis by quickly and objectively recognizing the low perfusion of tissue; and a diagnostic method using the same.

Abstract: A storage device of an ophthalmologic image display device of an embodiment stores a three dimensional data set acquired by scanning a subject's eye using OCT. An image processor forms, based on the three dimensional data set, a B-mode image, front images, and composite front image obtained from the front images. A display controller displays the B-mode image, front images and composite front image in a predetermined layout. The display controller displays distinguishment color information for distinguishment between the front images by colors and slice area information that indicates a partial region of the B-mode image corresponding to a slice area of the three dimensional data set represented by each front image in a color according to the distinguishment color information, and displays a composite front image based on the front images, each of which is expressed by a color according to the distinguishment color information.

Abstract: A method for establishing the refraction of an eye (9) by means of a refractometer (3) is provided, in which the current visual axis (S) of the eye (9) is established before establishing the refraction, the refractometer (3) is aligned with respect to the visual axis (S) of the eye (9) and the refraction is established after the alignment. The visual axis (S) of the eye (9) is established on the basis of the position of a Purkinje image of at least one light source (41, 50) used to illuminate the eye and a relationship between the position of the Purkinje image and the visual axis (S).

Abstract: Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured to generate an augmented image by overlaying an OCT image of target location and a graphical visual element identifying the locations, wherein the graphical visual element is registered with the microscope image to aid the surgeon in advancing a distal end of the elongate probe to the target location.

Abstract: A slit lamp device for use in an ophthalmoscope includes one or more light sources for providing a light path comprised of one or more beams of: visible light and infrared (IR) light; a slit lamp control mechanism along the light path for receiving the one or more light beams and forming the one or more light beams into a slit light beam; the slit lamp control mechanism further controlling the width of the formed slit light beam; a first, narrow slit passes visible light through the slit control mechanism and a second, wider slit passes IR light though the slit control mechanism.

Abstract: A wearable radio frequency receiver device is provided, which includes a receiver antenna configured to receive an interrogation signal from a transmitter. The receiver device further includes a sensor coupled to the receiver antenna and configured to receive a physiological input from a user wearing the device and generate a sensor signal based on the physiological input, and a modulator configured to perform direct modulation on the received interrogation signal based on the sensor signal to encode the physiological input in the directly modulated interrogation signal. The receiver antenna may be configured to reflect at least a portion of the directly modulated interrogation signal as backscatter radiation. A transceiver including a transceiver antenna may be provided to receive the directly modulated interrogation signal, and the modulation receiver may be configured to process the directly modulated interrogation signal and output a decoded physiological input.

Abstract: A deep machine-learning approach is used for medical image fusion by a medical imaging system. This one approach may be used for different applications. For a given application, the same deep learning is used but with different application-specific training data. The resulting deep-learnt classifier provides a reduced feature vector in response to input of intensities of one image and displacement vectors for patches of the one image relative to another image. The output feature vector is used to determine the deformation for medical image fusion.

Abstract: A Medical Body Area Network (MBAN) (10) includes a hub device (18) with a wireless communication transceiver (34). One or more sensor devices (14) each include a physiological sensor (24) for acquiring physiological data and a wireless communication transceiver (22) configured to connect with the wireless communication transceiver (34) of the hub device (18) to wirelessly transmit acquired physiological data to the hub device (18). One or more aggregator devices (16) each include a wireless communication transceiver (30) for receiving physiological data acquired by the one or more sensor devices (14). The hub device (18) is configured to respond to not wirelessly receiving a missing data portion of physiological data acquired by a sensor device (14) by requesting and receiving the missing data portion from an aggregator device (16).

Abstract: The present invention uses a time-series waveform of biosignal information collected from the back of a person and including biological sound and vibration (back body surface pulse wave). The back body surface pulse wave is pressure vibration arising from cardiac and aortic motions, and includes ventricular systolic and diastolic information and information on vascular wall elasticity which serves as an auxiliary pump for the circulation, and is considered as a vibration system including both the damping of viscous damping friction and the damping of solid friction. The back body surface pulse wave fluctuates according to a flow rate (stroke volume) of blood pumped out from the heart, and the fluctuation of this flow rate is reflected in the amplitude of the time-series waveform of the back body surface pulse wave.

Abstract: A medical imaging system for determining a scan orientation is provided. The system comprises: a computing device; a display device; an input device; and, an imaging device, the computing device configured to: instruct the imaging device to acquire at least a sagittal scout scan, an axial scout scan and a coronal scout scan, based on an initial frame of reference; render, at the display device: a two-dimensional representation of each of the scout scans and initial respective selections of a portion of each of the scout scans, oriented according to the initial frame of reference; receive, from the input device, a respective reorientation of one or more of the initial respective selections; transform the initial frame of reference using the respective to produce a reoriented frame of reference; and, instruct the imaging device to acquire further images based on the reoriented frame of reference.

Abstract: Detecting a movable object in a location includes providing a first 3D representation of at least part of a surface; providing a second 3D representation of at least part of the surface; determining for the first 3D representation a first excluded volume in space where no surface can be present; determining for the second 3D representation a second excluded volume in space where no surface can be present; if a portion of the surface in the first 3D representation is located in space in the second excluded volume, the portion of the surface in the first 3D representation is disregarded in the generation of the virtual 3D model, and/or if a portion of the surface in the second 3D representation is located in space in the first excluded volume, the portion of the surface in the second 3D representation is disregarded in the generation of the virtual 3D model.

Abstract: A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating the emission of fluorescence, due to one or more endogenous fluorophors in the tissue. Fluorescence anisotropy is then calculated. Such measurements of fluorescence anisotropy are then used to assess the functional status of the tissue, and to identify the existence and severity of disease states. Such assessment can be made by comparing a fluorescence anisotropy profile with a known profile of a control.

Abstract: A method for an optical elastography system converts digital images of an actuated breast into a description of surface motion. The surface motion can subsequently be used to ascertain whether the breast has regions of abnormal stiffness, e.g., indicating a significant likelihood of breast cancer. The steps of the method use a model based segmentation to identify profile of the breast in each image, and for each pair of images computing skin surface motion using an optical flow algorithm. This method eliminates a preliminary step of placing fiducial markers on the subject.

Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.

Abstract: A photoacoustic apparatus includes a light irradiation unit configured to irradiate a first irradiation region of a subject with first intensity modulated light corresponding to a first coding sequence and to irradiate a second irradiation region of the subject with second intensity modulated light corresponding to a second coding sequence, a reception unit configured to receive photoacoustic waves generated when the subject is irradiated with the first and the second intensity modulated light and output a first signal, and a processing unit configured to perform decoding processing on the first signal based on information on the first and the second coding sequences to acquire a first decoded signal corresponding to the first irradiation region or a second decoded signal corresponding to the second irradiation region.

Abstract: A subject information acquisition apparatus includes a light irradiation unit configured to irradiate a subject with light, a probe configured to detect an acoustic wave generated in the subject due to the irradiation of the light, a moving unit configured to change a relative position between the probe and the subject, and a control unit configured to control the moving unit to move the probe so that the probe makes a movement along a path a plurality of times. The moving unit is controlled so that the relative position of the probe with respect to the subject when the subject is irradiated with the light during a first movement along the path differs from the relative position of the probe with respect to the subject when the subject is irradiated with the light during a second movement along the path successively performed after the first movement along the path.

Abstract: A device and a method which monitors the pulse transit time of a heart beat is disclosed, i.e. the time taken for a heart impulse to travel from the heart to a limb of a subject. The time taken to travel is calibrated to blood pressure of the subject by a pre-determined formula. However, the calibration is augmented by empirical observations, obtaining several optional calibrations. The most suitable of the calibrations is selected to interpret each pulse transit time reading based on proximity of the pulse transit time. Hence, it is possible that every pulse transit time reading may use a different calibration. The method diminishes the effect of physiological change in the subject which causes drift in a solely formula based calibration.

Abstract: There is set forth herein an apparatus comprising: a non-contacting array of sensors adapted for positioning at a position spaced from and proximate a position of a patient; and a signal processing circuit in communication with the array of sensors, wherein the signal processing circuit is configured for: generating a plurality of time varying signals using the array of sensors; processing the plurality of time varying signals; and outputting one or more indicator based on the processing. The apparatus can be adapted for use in a variety of applications including emergency applications such as live birth applications in which neonate resuscitation protocols are observed.

Abstract: Method and systems provide for reliable, convenient, and cost-effective personalized assessment of hemodynamic status in the ambulatory heart failure patient. The method and apparatus use pulse contour analysis of data obtained through observation of the patient for determination of hemodynamic status, and for determination of day-to-day changes in hemodynamic status. Observational assessment of the patient includes monitoring during activities of daily living including sleeping, sitting and standing. These activities create changes in venous return that are used to evaluate cardiac function or changes in cardiac function. The method and system infer body position by using position and motion information obtained by the system. Changes in cardiac function over time or due to changes in body pose are evaluated for the assessment of hemodynamic status, with a focus on changes resulting from fluid overload.

Abstract: A charging method using an electrode of a biometric sensor, and an electronic device using the same are provided. A wearable electronic device includes a housing, at least one electrode exposed outwards from one surface of the housing, a battery provided inside the housing, a charger circuit connected electrically to the battery, at least one sensor, a switch configured to connect the charger circuit or the at least one sensor to the at least one electrode, and a processor connected electrically to the charger circuit, the at least one sensor, and the switch. The processor is configured to determine whether the wearable electronic device is coupled to a body, based on a signal acquired through the at least one sensor, and control the switch to connect the charger circuit or the at least one sensor to the at least one electrode in correspondence with a result of the determination.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: Disclosed is a method to measure a patient's blood pressure by a blood pressure measurement system utilizing a finger cuff, in which the finger cuff includes a light emitting diode (LED)—photodiode (PD) pair and a bladder. The method comprises: placing the finger cuff around the patient's finger such that the bladder and the LED-PD pair aid in measuring the patient's blood pressure by the blood pressure measurement system; and applying heat generated by a heating element to the finger of the patient to increase the temperature of the finger, wherein the heating element generates heat at a predetermined temperature. Also, in some embodiments, the heating element also includes warming the hand and the wrist.

Abstract: A physiological signal sensor to measure life signs includes at least one first and one second Doppler detectors, at least one first amplification filter, at least one second amplification filter, a processor, and a transceiver. Data from the physiological signal sensor is sent to the first and second Doppler detectors to detect first and second physiological signals from different locations on a living body. The two physiological signals are sent to the first and second amplification filters and amplified and filtered, and converted to obtain a first and second digital sensed signal. Digital signal processing is carried out on the digital sensed signals to obtain first and second physiological information which are outputted via the transceiver.

Abstract: An information processing apparatus is described. This determines a physiological parameter of an individual, the apparatus comprising: image circuitry configured to obtain a series of images of a skin exposed region of the individual; and processing circuitry configured to perform a periodogram on at least one of the red, green and blue channels of the skin exposed region of the series of images to obtain frequency components of the channel; and to determine the physiological parameter based on the periodogram.

Abstract: A watch or other type of portable electronic console that employs a number of different functions in order to improve its usability. The watch may, for example, allow a user to connect the watch to one or more remote electronic devices, such as an electronic performance sensor or MP3 player. The watch then displays information related to the connected electronic devices. Still further, the watch may allow a user to control the operation of one or more connected remote electronic devices. Thus, if the watch is connected to a remote speed/distance monitor employing a calibration variable, then the watch may allow the user to adjust the calibration variable.

Abstract: The present disclosure provides methods and systems for diagnosing and treating fibromyalgia in a patient. In one method, a pressure value is obtained for the patient, wherein the pressure value is determined by inserting a needle of a device into a location in the patient, injecting saline solution into the patient at the location, and measuring a pressure at the location: and fibromyalgia is diagnosed in the patient if the pressure at the location exceeds a threshold pressure value. The present disclosure also provides a device for use in the methods of the disclosure. One such device includes a needle, a syringe including a saline solution, a tube positioned between the syringe and the needle, and a pressure sensor configured to obtain a pressure value at a muscle location of a patient.

Abstract: An object is to provide an electrode catheter excellent in terms of torque transmission compared with a hitherto publicly known electrode catheter. An electrode catheter of the present invention comprises a catheter shaft 10; ring-shaped electrodes 201 to 210; and leads 301 to 310 of the ring-shaped electrodes 201 to 210, in which the catheter shaft 10 is constituted by an inside tube 11 that has a guide-wire lumen 11L and an outside tube 13 that forms a lumen 12L into which the leads 301 to 310 are inserted, the outside tube 13 being configured by a braided tube reinforced by a braid 135 made of a resin throughout the entire length thereof; in which side holes 15 are formed in the tube wall of the outside tube 13 at the distal end part 101 of the catheter shaft 10 in correspondence to the attachment positions of the ring-shaped electrodes 201 to 210; and in which the leads 301 to 310 enter the lumen 12L through the side holes 15 and extend in said lumen 12L.

Abstract: Computerized systems for automatically plotting electrocardiogram on a display device. The device may be polled to determine the configuration of the display, such as a screen height, length, resolution, etc. The display is divided into axes of a grid at particular spatial intervals fit to the display to form a dynamically-oriented background grid. The ECG signal is then plotted with data points corresponding in real time to the signal on the background grid to plot the ECG signal on the background grid, wherein the dividing and the synchronizing dynamically repositioning each grid line and each incoming data point based on a configuration of the display.

Abstract: A computer-implemented method and system is disclosed for modifying the properties of a consumable liquid to preventively treat or functionally correct human health conditions. The system includes a database storing human health conditions and an electronic device having a processor communicatively coupled to the database. The electronic device captures at least one visual image or video of a face of a person over a defined period of time via a digital camera. The captured images or video are processed by the electronic device to obtain the person's cardiointervalogram. From the cardiointervalogram, the electronic device identifies a particular human health condition of the person by comparing slow wave parameters of the cardiointervalogram to the corresponding human health conditions stored in the database. The electronic device then determines specified properties for light waves and/or acoustic waves based on the identified health condition(s).

Abstract: A method for determining a lowest stimulation threshold current level in a group of channels of a neuromonitoring device. The method includes stimulating tissue at a current level from a predetermined range of current levels as a sequence of pulses delivered at a frequency. The stimulating includes increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse by a first current increment. The method includes determining that a first evocation pulse from the sequence of pulses evokes a first muscular response. The method includes stimulating the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response. The stimulating includes decreasing the frequency of the delivery of each pulse in the sequence of pulses and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment.

Abstract: Disclosed is a portable monitoring module and a monitoring method utilizing the module for monitoring a plurality of electrical biosignals of a person. The module includes a measurement for measuring an electrical biosignal from the at least two electrodes, a wireless communication unit, and a processing unit. The processing unit selects a biosignal type to be monitored from a list of types supported by the monitoring module, store samples of biosignal data generated by the measurement unit, detect an indicator pattern within the biosignal data, wherein the indicator pattern represents an indication of a possible event of the selected biosignal type, and send a set of biosignal data wirelessly to a validation system. The set of biosignal data represents a sequence of samples of biosignal data related to the detected indicator pattern, and the validation system confirms the presence of the event in the received set of biosignal data.

Abstract: A system and method for non-invasively monitoring the hemodynamic state of a patient by determining on a beat-by-beat basis the ratio of lusitropic function to inotropic function as an index of myocardial well-being or pathology for use by clinicians in the hospital or by the patient at home. In one embodiment of the system a smartphone running an application program that is connected through the internet to the cloud processes electronic signals, first, from an electrocardiogram device monitoring electrical cardiac activity, and second, from a seismocardiogram device monitoring mechanical cardiac activity in order to determine such ratio as an instantaneous measurement of the hemodynamic state of the patient, including such states as sepsis, myocardial ischemia, and heart failure.

Abstract: Computational models and methods and systems of using the model to estimate variable time delay in the sensorimotor system of a subject are provided. The computational model can estimate variable time delays in the sensorimotor system, predict sensory states based on delayed sensory feedback, and/or control the system in real time. The subject can be a human or a primate. Simulation experiments can show how the model can explain a sensorimotor system's ability to compensate for delays during online learning and control.

Abstract: The invention relates to a device for neurovascular stimulation, at least comprising: at least one brain activity sensor, at least one cardiovascular sensor, at least one computing unit and at least one output unit. The computing unit comprises at least one task algorithm, wherein signals of at least the brain activity sensor and the cardiovascular sensor can be received by the computing unit, and wherein a task, which is in correlation with at least the signals from at least the brain activity sensor and the signals of the cardiovascular sensor, can be determined by means of the task algorithm and can be output by means of the output unit.

Abstract: A sensor module for a wearable vital sign monitoring device is disclosed. The sensor module includes a substrate having a first side and a second side opposite the first side. The sensor module also includes a sensor die mounted to the first side of the substrate. The sensor die is configured to monitor a vital sign of a user. The sensor module further includes a waterproof coating that conformally covers the sensor die, at least a portion of the first side of the substrate, and at least a portion of the second side of the substrate.

Abstract: A method and device that provide improved visualization of soft tissue, such as renal arteries, renal veins and lymph nodes in guiding catheter placement and positioning in the renal region or vasculature. The method and device enable visualization of an electrophysiology catheter application in the renal region which provides for improved imaging of renal structures, including renal arteries, along with one or more adjacent anatomical structures, including renal veins, lymph nodes, other adjacent organs and and/or other adjacent soft tissues that may adversely impact the formation of a lesion during a catheter ablation procedure in or around a renal artery.

Abstract: Provided herein are methods for analyzing in vivo a brain circuit. A method of the present disclosure may include using optogenetics to stimulate a first region of a brain of an individual, in conjunction with functional magnetic resonance imaging (fMRI) of different regions of the brain to determine a dynamic functional connection between individual neurons of the first region and a second region of the brain. The method may further include identifying a third region of the brain, the neurons of which region mediate the dynamic functional connection between the first and second regions.

Abstract: The present disclosure provides apparatuses and computer readable media for measuring sub-epidermal moisture in patients to determine damaged tissue for clinical intervention. The present disclosure also provides methods for determining damaged tissue.

Abstract: Devices and methods are provided for non-invasive goal oriented and personalized monitoring of substance consumption directed towards aiding reduction of substance intake by a user. Based on the substance consumption characteristics and the user's profile, the user's substance consumption profile is identified and average amount of the substance in the body at a given time is computed. A threshold corresponding to amount of substance the body can sustain is then computed based on goals set by the user and the substance consumption characteristics and the user's profile. Alerts can be generated and transmitted to the user based on pre-determined conditions to help the user achieve his set goals.

Abstract: An electronic incentive spirometer has a base and a sensing device. The base is provided with a breathing tube and at least one vertical tube. A floating ball is disposed in the vertical tube, one end of the vertical tube connected to the breathing tube. The sensing device is disposed on the vertical tube of the base, has a sensing unit corresponding with the vertical tube and a control circuit, and the sensing unit is electrically connected to the control circuit.

Abstract: A walking assistance method may include measuring a current gait motion of a user, defining a state variable based on the current gait motion, setting a delay that is a feedback element for the state variable, and generating a torque profile based on the state variable and the delay.

Abstract: The present invention relates to a patient off-bed notification system, which includes a pressure-sensitive sensor pad, a signal converter, and a signal transmitter. The pressure-sensitive sensor pad includes an upper conductive layer, a bottom conductive layer, and an insulating layer arranged therebetween, where the upper conductive layer and the bottom conductive layer can generate an electrical signal due to a pressure change. The signal converter is used to receive the electrical signal from the pressure-sensitive sensor pad and perform operational analysis to produce a corresponding patient status signal. The signal transmitter transmits the patient status signal from the signal converter to a server, and the server displays or/and stores corresponding information according to the patient status signal. Thus, patient's statuses in bed can be known at any time, and the harm caused when the patient leaves the bed alone can be minimized, thus effectively improving the work efficiency of caregivers.