Abstract: The present disclosure provides compositions and methods for accurately detecting mutations by uniquely tagging double stranded nucleic acid molecules with dual cyphers such that sequence data obtained from a sense strand can be linked to sequence data obtained from an anti-sense strand when sequenced, for example, by massively parallel sequencing methods.

Abstract: Described herein are microparticles each comprising a plurality of bound biological molecules. Further described herein is a plurality of microdroplets each comprising one or more primer vehicles. Methods of making and using these microdroplets are also reported. An exemplary microparticle is of Formula (I).

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Current procedures for the analysis of sexual assault kits are labor intensive, time consuming and deliver a success rate lower than 40%. This has resulted in rape kit backlogs of thousands. The primary challenge crime laboratories face in analyzing these cases is the separation of purified male DNA from the mixture of primarily female DNA from gynecological swabs. Effective elution of the sample from the swab and efficient separation of intact sperm cells from epithelial and other cellular debris, allow for a successful PCR amplification and short tandem repeat (STR) DNA analysis for perpetrator identification. The disclosure provides an effective and economically accessible technology for the separation of male and female cells and DNA, for example, from a gynecological swab by capillary zone electrophoresis (CZE).

Abstract: The present invention relates to a method for determining a decrease in the functions of the hippocampus by using the correlation between a micro RNA (miRNA) and an N-methyl-D-aspartate receptor (NMDAR), a method for inhibiting the decrease in the functions, and a method for screening for inhibitors of the decrease in the functions.

Abstract: The disclosure includes methods of determining the activity of an inhibitor of a target microRNA (miRNA) or of a mimic of a target microRNA. Determination of polysome occupancy in treated and control samples followed by comparing the occupancies can be used to determine a displacement value for the inhibitor or mimic of the target miRNA. The displacement value reflects the extent of a change in the levels of the target miRNA (which may include the mimic if applicable) in polysomal and non-polysomal compartments of a sample or a shift of the target miRNA between polysomal and non-polysomal compartments of a sample and can indicate the activity of the inhibitor toward the target miRNA or of the mimic toward a target RNA.

Abstract: The present invention relates to a single nucleotide polymorphism (SNP) rs3815496 or any SNP having 100% of linkage disequilibrium with this SNP as a biomarker for assessing the risk of developing adverse effects after radiotherapy in a subject, in particular acute and/or subacute dermatitis and lymphocyte apoptosis.

Abstract: The invention relates to prenatal detection methods using non-invasive techniques. In particular, it relates to prenatal diagnosis of a fetal chromosomal aneuploidy by detecting fetal and maternal nucleic acids in a maternal biological sample. More particularly, the invention applies multiplex PCR to amplify selected fractions of the respective chromosomes of maternal and fetal chromosomes. Respective amounts of suspected aneuploid chromosomal regions and reference chromosomes are determined from massive sequencing analysis followed by a statistical analysis to detect a particular aneuploidy.

Abstract: High-throughput long read sequencing is used to perform immunogenomic characterization of expressed antibody repertoires in the context of vaccination. Informatic analysis allows global characterizations of isotype distributions, determination of the lineage structure of the repertoire and measure age and antigen related mutational activity. Global analysis of the immune system's clonal structure provides direct insight into the effects of vaccination and provides a detailed molecular portrait of age-related effects.

Abstract: Provided herein is a method for identifying a genetic variant that is associated with development of a condition of interest (e.g., Alzheimer's disease), and genetic variants so identified. Methods of treatment with an active agent (e.g., with a particular active agent and/or at an earlier age) is also provided, upon detecting a genetic variant described herein. In some embodiments, the genetic variant is a deletion/insertion polymorphism (DIP) of the TOMM40 gene. Kits for determining if a subject is at increased risk of developing late onset Alzheimer's disease is also provided. Kits for determining if a subject is responsive to treatment for a condition of interest with an active agent are further provided.

Abstract: The present invention relates to the therapy, prophylaxis and diagnosis of disorders that are associated with aberrant bone mineral density, in particular osteoporosis; wherein the level of selected microRNAs in samples of patients are detected and wherein an increase or decrease of said level compared to the level of healthy indivduals is indicative of the disorder.

Abstract: The present disclosure generally relates to methods and reagents for the diagnosis, prognosis or the monitoring of estrogen receptor 1 (ESR1) positive breast cancer, for example, ESR1 positive breast cancer which is responsive to endocrine therapy and/or ESR1 positive breast cancer which is refractory to endocrine therapy. The present disclosure also relates generally to treatment management of ESR1 positive breast cancer.

Abstract: Methods and kits for triaging a human papillomavirus (HPV)-positive woman into colposcopy are disclosed. The methods comprise determining the promoter methylation level of the promoter regions of a group of genes (e.g., viral and host genes) that exhibit increased promoter methylation in women having CIN2+ lesions as compared to women having no intraepithelial lesions or malignancy (NILM).

Abstract: The present invention provides methods to detect prostate cancer by detecting the RNA encoded by PCA3. The disclosure provides a method for determining a predisposition, or presence of prostate cancer comprising: (a) contacting a sample with at least one oligonucleotide that hybridizes to a PCA3 polynucleotide; (b) detecting an amount of PCA3 and second prostate-specific polynucleotides; and (c) comparing the amount of PCA3 polynucleotide that hybridizes to the oligonucleotide to a predetermined cut off value, and determining the presence or absence of prostate cancer. Diagnostic kits are provided for detecting prostate cancer or the risk of developing same comprising: (a) at least one container means containing at least one oligonucleotide probe or primer that hybridizes to PCA3 (b) at least one oligonucleotide probe or primer that hybridizes with a second prostate specific nucleic acid; and (c) reagents for detecting PCA3 and the second prostate specific nucleic acid.

Abstract: The present invention provides three new antisense long non coding RNAs (lncRNAs) that allow to diagnose prostate cancer much more accurately than the existent non-invasive diagnostic tools. So, this invention relates to the use of at least one of these antisense 1ncRNA or a combination thereof as a diagnosis marker for prostate cancer. It also relates to an in vitro method for prostate cancer diagnosis of a subject as well as to a kit for performing this method.

Abstract: Methods of evaluating tumor mutational burden in a sample, e.g., a tumor sample or a sample derived from a tumor, from a subject, are disclosed.

Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.

Abstract: The invention provides cotton event MON 88701, and plants, plant cells, seeds, plant parts, and commodity products comprising event MON 88701. The invention also provides polynucleotides specific for event MON 88701 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 88701. The invention also provides methods related to event MON 88701.

Abstract: Methods and compositions for identifying novel genes useful for modulating desired agronomic traits in plants are presented herein. The present disclosure relates to methods for identifying line-specific and cluster-specific genes from plants that show perturbation of expression in response to perturbation of expression of a primary gene, and the perturbation of expression of the line-specific or cluster-specific gene confers alterations in agronomic characteristics upon the plant.

Abstract: Systems and methods (S/M) to detect stress in stem cells are described. The S/M, including modified stem cells, assays and high throughput screens, can be used to identify compounds or other potential stressors that can negatively affect development potential.

Abstract: The present invention provides methods for detecting viral infectivity and content in an enzyme preparation. In certain embodiments, the invention relates to methods for producing a pharmaceutical pancreatic enzyme composition. In additional embodiments, the invention relates to detecting infectious porcine parvovirus (PPV) and determining PPV content in pancreatic enzyme preparations (PEPs), including pancrelipase preparations.

Abstract: The invention provides a unique subset of GH30 subfamily 8 xylanases (GH30-8) with endo-?-1,4-xylanase activity, compositions comprising an effective amount of the GH30-8 xylanases, methods of synthesis and methods of use thereof.

Abstract: The invention relates to a process for the removal of contaminants from a liquor, the process comprising: introducing a metal or ammonium hydroxide into the liquor; introducing the liquor into a reaction vessel; bubbling a carbon dioxide gas comprising at least 25% carbon dioxide through the liquor within the reaction vessel; and separating the precipitate formed by the carbonation of the metal hydroxide from the liquor, the precipitate comprising at least some of the contaminants from the liquor; wherein, on average, the liquor is resident within the reaction vessel for a period of no more than about 60 minutes. The invention also relates to a process for the removal of contaminants from a liquor, the process comprising: introducing a metal or ammonium hydroxide into the liquor and bubbling a carbon dioxide gas comprising at least 25% carbon dioxide through the liquor to fom1 a precipitate by carbonation in a period of no more than about 60 minutes.

Abstract: Sweeteners made from the co-crystallization of 3-(4-amino-2,2-dioxide-1H-benzo[c][1,2,6]thiadiazin-5-yloxy)-2?,2?-dimethyl-N-propylpropanamide (Compound I) having the structure: or salt thereof, with sugar in various ratios. The sugar co-crystallized sweeteners are very soluble in water and have no dusting problems.

Abstract: A method for producing liquid pig iron (1), includes reducing iron-oxide-containing feed materials (2) to form a partially reduced first iron product (3) in a first reduction system (4), introducing the partially reduced first iron product (3), a first oxygen-containing gas (9, 9a), and a first carbon carrier (10) into a melter gasifier (11), introducing a second gaseous and/or liquid carbon carrier (13) and a second oxygen-containing gas (9b) into a mixing region (18) within the melter gasifier (11) above the fixed bed of the melter gasifier, mixing the second gaseous and/or liquid carbon carrier (13) with the second oxygen-containing gas (9b) in the mixing region (18), wherein the combustion air ratio is set in the range of 0.2 to 0.4, preferably between 0.3 and 0.

Abstract: A slag conditioner for electric arc furnace steel production comprising a carbonate-containing material with the balance being a reducing agent that comprises a reducing element that is easily oxidized in an exothermic reaction. The slag conditioner may further include carbonaceous material and/or an MgO-containing material. The slag conditioners may be in particulate, pellet, or briquette form. Also, a method of conditioning the slag in an electric arc furnace where steel in being produced, the method comprising introducing the particulate or pellet slag conditioners into the slag or into an interface between the slag and the molten metal or charging the briquette slag conditioners into the top of the furnace.

Abstract: A production method for smelting clean steel from full-scrap steel using duplex electric arc furnaces, which belongs to the field of electric arc furnace steelmaking. This method makes electric arc furnaces located in two positions be connected in series, wherein the electric arc furnace in a first position is dephosphorization electric arc furnace, and the electric arc furnace in a second position is decarbonization electric arc furnace.

Abstract: The invention relates to granules composed of agglomerated reactive bulk material and a binder matrix, the binder matrix comprising as binder an organic or inorganic salt.

Abstract: The invention relates to a method and to a device for heat treating a metal component. The method comprises at least the following steps: a) heating the component; b) setting a temperature difference between at least one first sub-region and at least one second sub-region of the component; c) at least partially forming and/or cooling the component in a press hardening tool; and d) mechanically post-processing the at least one first sub-region of the component.

Abstract: Provided are a high-speed tool steel having excellent hot workability, and excellent damage resistance when made into various tools; a material for tools, and a method for producing the same. The high-speed tool steel contains, in mass %, 0.9-1.2% of C, 0.1-1.0% of Si, 1.0% or less of Mn, 3.0-5.0% of Cr, 2.1-3.5% of W, 9.0-10.0% of Mo, 0.9-1.2% of V, 5.0-10.0% of Co, 0.020% or less of N, and the remainder being Fe and impurities, wherein an M value calculated by a formula satisfies ?1.5?M value?1.5. Formula: M value=?9.500+9.334[% C]?0.275[% Si]?0.566[% W]?0.404[% Mo]+3.980[% V]+0.166[% Co], where the characters in brackets [ ] indicate the contained amounts (mass %) of the respective elements. The present invention also pertains to: a material for tools, which is obtained by using the high-speed tool steel; and a method for producing the material for tools.

Abstract: The present invention provides a high-strength steel and a production method therefor, the high-strength steel: comprising, in wt %, C: 0.05-0.09%, Mn: 1.5-2.2%, Ni: 0.3-1.2%, Nb: 0.005-0.04%, Ti: 0.005-0.004%, Cu: 0.1-0.8%, Si: 0.05-0.03%, Al: 0.005-0.05%, P: 100 ppm or less, S: 40 ppm or less, and a remainder made up by Fe and other inevitable impurities; having a center part microstructure comprising an acicular ferrite and granular bainite mixed-phase, upper bainite, and a remainder made up by one type or more selected from the group consisting of ferrite, pearlite, and a martensite-austenite (MA) constituent; having, in a 2 mm or less subsurface region, a surface part microstructure comprising ferrite and a remainder made up by one type or more among bainite and martensite, and having a welding heat affected zone, which is formed during welding, that comprises, in area %, 5% or less of a martensite-austenite constituent.

Abstract: A high strength hot dip galvanised steel strip consisting, in mass percent, of the following elements: 0.10-0.21% C, 1.45-2.20% Mn, max. 1.50% Si, 0.1-1.50% Al, 0.001-0.04% P, 0.0005-0.005% B, 0.005-0.30% V, max. 0.015% N, max. 0.05% S, and, optionally, one or more elements: max. 0.004% Ca, max. 0.10% Nb, max. 0.50% Cr, max. 0.20% Mo, max. 0.20%, Ni, max. 0.20% Cu, and max. 0.20% Ti the balance of the composition consisting of Fe and inevitable impurities. The steel has good surface finish and increased mechanical strength, in particular high overall strength, ductility and plasticity. It also relates to a process for the manufacture of a high strength hot dip galvanised steel strip and to the products thereof.

Abstract: Provided are a material for cold rolled stainless steel sheets having sufficient corrosion resistance, excellent surface quality, excellent formability, and excellent ridging resistance; a method for manufacturing the same; and a cold rolled steel sheet. A material for cold rolled stainless steel sheets according to the present invention contains C: 0.005% to 0.025%, Si: 0.02% to 0.50%, Mn: 0.55% to 1.0%, P: 0.040% or less, S: 0.01% or less, Cr: 15.5% to 18.0%, Ni: 0.01% to 1.0%, Al: 0.001% to 0.10%, and N: 0.005% to 0.025% on a mass basis, the remainder being Fe and inevitable impurities, and has a metallographic structure containing 5% to 20% of a martensite phase in terms of volume fraction, the remainder being a ferrite phase.

Abstract: Provided is an ultra high-strength steel sheet having excellent hole expandability. The ultra high-strength steel sheet includes: 0.15 to 0.30% of C, 1.0 to 3.0% of Si, 3.0 to 5.0% of Mn, 0.020% or less of P, 0.010% or less of S, 0.01 to 3.0% of Al, and 0.020% or less of N (excluding 0%) by weight, with the remainder consisting of Fe and other inevitable impurities, wherein a microstructure contains 5% to 20% by area fraction of retained austenite with the remainder including ferrite, bainite and fresh martensite.

Abstract: A method for thermal processing rails including casting a rail from a metal, allowing the rail casting to cool to a temperature within a predetermined range, immediately placing the rail casting, when at the temperature, into a first chamber having gaseous nitrogen, cooling the rail casting to about ?300 degrees using the gaseous nitrogen, allowing the rail casting to soak in a second chamber having liquid nitrogen and allowing the rail casting to reach room temperature.

Abstract: Methods for induction surface hardening of a ring surface of a work piece. The ring surface and a hardening device have an induction coil moved relative to one another in a treatment direction in a feed mode. A sprinkler located downstream of the induction coil in the direction of treatment serves to heat the ring surface, starting from an initial zone to a final zone, with the induction coil and then hardens it by cooling the ring surface with the sprinkler. An unhardened soft zone is provided between the initial zone and the end zone. The supplementary induction coil, the induction coil and the sprinkler are activated and deactivated separately at the start of hardening and at the end of hardening, respectively, the speed between the hardening device and the work piece and/or the power supplied to the supplementary induction coil and the induction coil varied at the same time.

Abstract: In an austenitic stainless steel sheet, the arithmetic average roughness Ra is 0.2 ?m or more and 1.2 ?m or less. In addition, the dull pattern transfer rate on the steel sheet surface is 15% or more and 70% or less. Furthermore, micropits with a depth of 0.5 ?m or more and an open area of 10 ?m2 or more which are formed on the steel sheet surface have an existing density of 10.0 or less per 0.01 mm2 and an open area ratio of 1.0% or less. In addition, a film formed on the steel sheet surface is constituted from an oxide containing SiO2 as a main constituent, which oxide contains at least Si, N, Al, Mn, Cr, Fe, Nb, Ti and O as film-forming elements other than C, wherein the Si content is 10 at % or more, and the N content is 10 at % or less.

Abstract: A high strength steel sheet having excellent surface quality and formability with a tensile strength of 980 MPa or more and a TS-El balance of 30000 MPa % or more is provided. A high strength steel sheet comprises: a chemical composition containing C: 0.08% to 0.30%, Si: 2.0% or less, Mn: more than 3.0% and 10.0% or less, P: 0.05% or less, S: 0.01% or less, Al: 1.5% or less, Ti: 0.010% to 0.300%, and N: 0.0020% to 0.0100% in a range satisfying 1.1?(Ti+Mn1/2/400)/(0.01+5N)?6.0; and a microstructure including a retained austenite phase and a ferrite phase, wherein a ratio ?Mn/?Mn of an average Mn concentration (?Mn) of the retained austenite phase to an average Mn concentration (?Mn) of the ferrite phase is 1.5 or more.

Abstract: The hot-rolled Nb-containing ferritic stainless steel sheet of the present invention has a composition containing C: 0.030 mass % or less, Si: 2.00 mass % or less, Mn: 2.00 mass % or less, P: 0.050 mass % or less, S: 0.040 mass % or less, Cr: 10.00 mass % to 25.00 mass %, N: 0.030 mass % or less and Nb: 0.01 mass % to 0.80 mass %, with the balance being made up of Fe and unavoidable impurities. In this hot-rolled Nb-containing ferritic stainless steel sheet, the precipitation amount of Nb carbonitrides is 0.2 mass % or more, and the number of Laves phases having a grain size of 0.1 ?m or less is 10 or fewer per 10 ?m2 of surface area.

Abstract: Provided is a cold-rolled steel sheet manufactured by a cold-rolled steel sheet manufacturing method comprising a continuous annealing step, which has a composition comprising, by weight %: C: 0.1-0.15%; Si: 0.2% or less (including 0%); Mn: 2.3-3.0%; P: 0.001-0.10%; S: 0.010% or less (including 0%); Sol.Al: 0.01-0.10%; N: 0.010% or less (excluding 0%); Cr: 0.3-0.9%; B: 0.0010-0.0030%; Ti: 0.01-0.03%; Nb:0.01-0.03%; the balance being Fe and other impurities, and satisfies following relationship 1. [relationship 1] 1650?5541.4C+239Mn+169.1Cr+0.74SS?1.36RCS?1688, in which microstructure comprises, in area %, at least 90% of martensite and tempered martensite; and 10% or less of ferrite and bainite, in which the fraction of the tempered martensite in the martensite and the tempered martensite is 90% or more, in area %, and the ratio (b/a) of the C+Mn concentration (a) in the martensite to the C+Mn concentration (b) in the ferrite and the bainite is 0.65 or more.

Abstract: A thick steel plate for high heat input welding and having great heat-affected area toughness and a manufacturing method therefor, comprising the steps of smelting, casting, rolling, and cooling. Chemical composition is properly controlled for the steel plate and satisfies 1?Ti/N?6 and Mg/Ti>0.017, where effective S content in steel=S?1.3 Mg?0.8 Ca?0.34 REM?0.35 Zr, and effective S content in steel: 0.0003-0.003%; finely dispersed inclusions may be formed in the steel plate, and the amount of composite inclusion MgO+Ti2O3+MnS in the steel plate is controlled at a proportion greater than or equal to 5%. The tensile strength of a base material so acquired is ?510 MPa, insofar as welding input energy is 200?400 kJ/cm, the average Charpy impact work of the steel plate at ?40 ° C. is 100 J or more, at the same time, the average Charpy aging impact work of the base material of ½ thickness at ?40° C. is 46 J or more.

Abstract: Disclosed herein is a high-strength galvannealed steel sheet having a galvannealed layer on a surface of a base steel sheet and containing predetermined steel components. The steel sheet sequentially has, from the interface of the base steel sheet and the galvannealed layer, towards the base steel sheet: an internal oxide layer and containing at least one oxide selected from the group consisting of Si and Mn; a soft layer including the internal oxide layer, and satisfying a predetermined Vickers hardness; and a hard layer made up of a structure mainly composed of martensite. The average depth D of the soft layer is 20 ?m or greater, and the average depth d of the internal oxide layer is 4 ?m or greater and smaller than D. A coefficient of variation of KAM of the base steel sheet at the portion t/4 is 0.66 or less.

Abstract: A dual-hardness clad steel plate. One surface of the steel plate is a high-hardness layer, the other surface of the steel plate is a low-hardness layer, and a combination of atoms is achieved between the high-hardness layer and the low-hardness layer by rolling bonding, wherein Mn13 steel is adopted for the low-hardness layer, and the Brinell hardness of the high-hardness layer is greater than 600. Further disclosed is a production method of the dual-hardness clad steel plate, comprising: 1) respectively preparing a high-hardness layer slab and a low-hardness layer slab; 2) assembling: preprocessing combined faces of the slabs, carrying out peripheral welded sealing on joint faces of the slabs, and carrying out vacuumizing treatment on a composite slab after welded sealing; 3) heating; 4) carrying out composite rolling; 5) cooling; and 6) carrying out thermal treatment, wherein the heating temperature is 1050-1100° C.

Abstract: A continuous annealing furnace for annealing steel strips has a reaction chamber wherein the steel strips are transported vertically, the reaction chamber having openings supplied with a reactant, also called reactant openings, located at the top or at the bottom of the reaction chamber, wherein the reaction chamber further has other openings supplied with an inert gas, also called inert gas openings, the inert gas openings being located on the lateral sides of the reaction chamber.

Abstract: Apparatus for heat treating magnetic wire includes a wire supply unit, a wire property measuring unit, a wire tensile force measuring unit, a heat treatment unit, and a wire winding unit. The wire supply unit includes a supply bobbin, a supply rotary part, a wire reel, and a tension roller. The wire property measuring unit includes a size measuring device, an after measurement capstan, and a wire reel and measures a size of the wire prior to the heat treatment. The wire tensile force measuring unit includes a tensile force measuring device, a tension roller, and a wire reel. The wire heat treatment unit includes a heat treatment furnace, a temperature measuring device, an after heat treatment capstan, and a wire reel. The wire winding unit includes a winding bobbin, a winding rotary part that rotates the winding bobbin, a tension roller, and a wire reel.

Abstract: A vehicle component strength zone forming method is provided. The method includes identifying a condition of a blank via sensors at a furnace inlet. The method further includes outputting, by a controller, furnace command signals based on a predetermined thermal treatment schedule for the identified condition of the blank to heat a first blank portion to form a fully martensitic microstructure and heat a second blank portion to form a microstructure having one or more of ferrite, pearlite, and austenite. The method may further include outputting the furnace command signals based on furnace temperature variations detected by furnace sensors in communication with the controller. The method may further include outputting the furnace command signals based on one or more of a detected blank chemical composition, a detected type of blank coating, a detected blank thickness, and a detected blank material type.

Abstract: Apparatus for heat treating magnetic wire includes a wire supply unit, a wire property measuring unit, a wire tensile force measuring unit, a heat treatment unit, and a wire winding unit. The wire supply unit includes a supply bobbin, a supply rotary part, a wire reel, and a tension roller. The wire property measuring unit includes a size measuring device, an after measurement capstan, and a wire reel and measures a size of the wire prior to the heat treatment. The wire tensile force measuring unit includes a tensile force measuring device, a tension roller, and a wire reel. The wire heat treatment unit includes a heat treatment furnace, a temperature measuring device, an after heat treatment capstan, and a wire reel. The wire winding unit includes a winding bobbin, a winding rotary part that rotates the winding bobbin, a tension roller, and a wire reel.

Abstract: Disclosed is a method of recovering rare earth, aluminum and silicon from rare earth-containing aluminum-silicon scrap. The method comprises: S1, acid-leaching the rare earth-containing aluminum-silicon scrap with an inorganic acid aqueous solution to obtain a silicon-rich slag and acid leached solution containing rare earth and aluminum element; S2, adding an alkaline substance into the acid leached solution containing the rare earth and aluminum element and controlling a PH value of the acid leaching solution between 3.5 to 5.2, performing a solid-liquid separation to obtain a aluminum hydroxide-containing precipitate and a rare earth-containing solution filter; S3, reacting the aluminum hydroxide containing precipitate with sodium hydroxidee to obtain sodium metaaluminate solution and aluminum-silicon slag, and preparing a rare earth compound product with the rare earth-containing filtrate.