Patents Issued in December 27, 2018
  • Publication number: 20180369505
    Abstract: The present invention relates to a treatment device and a method for controlling the same, and provides a treatment device comprising: an insertion unit formed to be insertable in tissue after penetrating through a surface of the tissue; a displacement measuring unit for measuring displacement of the surface of the tissue, caused by an insertion of the insertion unit; and a control unit for controlling an insertion motion of the insertion unit on the basis of the displacement measured by the displacement measuring unit. According to the present invention, the device allows medical treatment in a state in which the insertion unit has been inserted to reach a precise position of a target, so as to improve an effect of medical treatment.
    Type: Application
    Filed: November 17, 2016
    Publication date: December 27, 2018
    Inventor: Kwang Chon KO
  • Publication number: 20180369506
    Abstract: Medicament delivery devices are described herein. In some embodiments, an apparatus includes a medical injector and an electronic circuit system. The medical injector includes a housing, a medicament container, and a medicament delivery member. The housing defines a first region and a second region. The first region includes the medicament container and is physically isolated from the second region. The electronic circuit system is configured to be disposed within the second region defined by the housing. The electronic circuit system is configured to output an electronic output associated with a use of the medical injector.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 27, 2018
    Applicant: kaleo, Inc.
    Inventors: Eric S. EDWARDS, Evan T. EDWARDS, Mark J. LICATA, Paul F. MEYERS, David A. WEINZIERL
  • Publication number: 20180369507
    Abstract: A medical nebulizer with improved structure, the medical nebulizer comprising a first housing and a second housing, the first housing integrally formed a first nozzle, the first nozzle has a first nozzle hole, the second housing integrally formed a second nozzle and a conical cover, the second nozzle has a second nozzle hole, the inside of the conical cover has a protrusion and an annular inclined surface, the protrusion formed a impacting surface to produce aerosol; wherein the second housing is separable assembled to the first housing, the second nozzle is located on the outside of the first nozzle, a fluid passage is formed between the first nozzle and the second nozzle, the first nozzle hole is located on the inside of the second nozzle hole, the impacting surface is located above the second nozzle hole.
    Type: Application
    Filed: August 2, 2017
    Publication date: December 27, 2018
    Inventors: Tao-Tsun HSIUNG, Xu-Xiang WANG
  • Publication number: 20180369508
    Abstract: The present invention relates to air-flow in a nebulizer head. In order to provide a nebulizer head with an improved air-flow guidance, a nebulizer head (10) comprises a housing structure (12) providing an air-flow path (16) with two opposite air-flow openings (18a, 18b), and a fluid reservoir (14) provided to accommodate a liquid from which small droplets are to be generated in order to form an aerosol, and an aerosol generator (20) with an aperture member (22) that comprises an aperture surface (24) with a plurality of apertures to provide the small droplets from the liquid. The fluid reservoir is arranged adjacent the aerosol generator such that the aperture member is in contact with the fluid. The aerosol generator is arranged within the air-flow path. At least one by-pass flow path (26) is provided between the aerosol generator and the housing structure. The air-flow path is a bidirectional path that provides a first air-flow direction (28) for inhaling, and a second air-flow direction (38) for exhaling.
    Type: Application
    Filed: December 21, 2016
    Publication date: December 27, 2018
    Inventors: DIRK ERNEST VoON HOLLEN, FILIPPO QUADRELLI, MICHAEL DUNCAN
  • Publication number: 20180369509
    Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 27, 2018
    Applicant: Stamford Devices Limited
    Inventors: Patrick Joseph POWER, Jimmy EATON-EVANS
  • Publication number: 20180369510
    Abstract: The present invention relates to an insufflator comprising an insufflation hose with an integrated heating element and a humidifying medium for use in laparoscopy, wherein the heating wire is adapted to measure the resistance and permits a refill alarm.
    Type: Application
    Filed: March 16, 2017
    Publication date: December 27, 2018
    Inventors: Yves KOETH, Felix MENZEL
  • Publication number: 20180369511
    Abstract: A gas conditioning unit for a surgical gas delivery device is disclosed, which includes a filter housing having an insufflation gas flow path for delivering insufflation gas to a body cavity and for facilitating pressure measurements from the body cavity, a pressurized gas flow path for delivering pressurized gas from a pump in the surgical gas delivery device to an internal nozzle in the filter housing that accelerates the pressurized gas and thereby generates a continuous pressure barrier that inhibits egress of insufflation gas from the body cavity, a vacuum return flow path for returning depressurized gas spent by the internal nozzle back to the pump under vacuum, an air entrainment flow path for drawing air into the body cavity to maintain a given pressure therein, and a smoke evacuation flow path for conveying smoke from the body cavity.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Inventors: Earl M. Zergiebel, Michael J. Augelli, Kenneth Blier, Ralph Stearns
  • Publication number: 20180369512
    Abstract: A flow governor assembly for use with a medicinal inhaler. The assembly can include a housing that defines an air flow path; a flow governor positioned in the air flow path to govern air flow in the air flow path to a target governing volumetric flow rate; and a constriction in the air flow path. The flow governor can be configured to provide a variable, or dynamic, resistance to air flow in the air flow path as a function of air pressure drop between an inlet and an outlet of the flow governor. The constriction can be configured to provide a fixed, or static, resistance to air flow in the air flow path.
    Type: Application
    Filed: December 13, 2016
    Publication date: December 27, 2018
    Inventors: CHRISTOPHER G. BLATCHFORD, ROMAIN U.G. GUION, CHRISTOPHER B.J. GROOMBRIDGE, SIMON L. CALCUTT
  • Publication number: 20180369513
    Abstract: A unit dose dry powder inhaler includes a base defining a capsule seat that holds a capsule of medicament and an air intake that is in fluid communication with the capsule seat. The intake draws air into the capsule seat to generate rapid capsule precession and centrifugal forces that fluidize and disperse powder agglomerates. Entrained powder is drawn through a grid to disperse powder agglomerates via impaction forces. An inlet funnel between the grid and a dispersion chamber tapers to a small inlet orifice into the dispersion chamber to disperse powder agglomerates via shear forces generated at the orifice. The chamber entrains powder from the inlet funnel and holds an actuator that oscillates during inhalation to disperse powder agglomerates by dynamic impaction with the actuator and increased turbulence within the chamber. A tapered outlet funnel reduces particle velocity and turbulence and provides an exit for air and aerosolized medicament.
    Type: Application
    Filed: April 17, 2018
    Publication date: December 27, 2018
    Inventors: James Hannon, Dan Deaton, Shirley Lyons, Jeffry Weers, Robert Curtis
  • Publication number: 20180369514
    Abstract: The present disclosure relates to an inhaler for dispensing metered doses of aerosolized medication from an aerosol container that contains a formulation for inhalation by a user, wherein the inhaler comprises one or more processors that are operatively coupled to a memory for monitoring and recording medication dose parameters based on consumption of the medication by the user. Exemplary dose parameters can include any or a combination of timing of dose consumption, size of each dose, frequency of doses, and effectiveness grade of the prescribed dose of medication, wherein the effectiveness grade is determined based on a feedback signal received from the user after the metered dose is consumed, wherein the feedback signal is received by the inhaler from any or a combination interface of the inhaler or from a portable computing device that the inhaler is operatively coupled with.
    Type: Application
    Filed: June 27, 2018
    Publication date: December 27, 2018
    Applicant: Resolve Digital Health Inc.
    Inventor: Robert ADELSON
  • Publication number: 20180369515
    Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 ?m, so as to target the pulmonary system of the user.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 27, 2018
    Applicant: PNEUMA RESPIRATORY, INC.
    Inventors: Louis Thomas Germinario, John H. Hebrank, Charles Eric Hunter, Jack C. Hunter, Chengjie Li, Christopher W. Maurer
  • Publication number: 20180369516
    Abstract: The present disclosure relates to a drop dispenser device comprising: a liquid reservoir for holding a liquid medicament to be vaporized; a dispensing opening through which the liquid medicament is adapted to pass during a dispensing operation of the dispenser; and a dispensing mechanism configured to generate predetermined droplets of the liquid medicament, and expel the generated droplets through the dispensing opening in a selected liquid amount and at a selected frequency, upon activation of the dispensing mechanism.
    Type: Application
    Filed: June 26, 2018
    Publication date: December 27, 2018
    Applicant: Resolve Digital Health Inc.
    Inventor: Robert ADELSON
  • Publication number: 20180369517
    Abstract: A nicotine powder delivery system includes an inhaler article and a nicotine powder capsule disposed within the inhaler article. The nicotine powder capsule rotates about a longitudinal axis when air flows through the inhaler article.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 27, 2018
    Inventor: Gerard Zuber
  • Publication number: 20180369518
    Abstract: An aspect of the present disclosure provides a piercing device for use with an inhalation device, the piercing device including: at least one perforator; a plurality of passages defined along said at least one perforator; and at least one heating mechanism incorporated into said at least one perforator, wherein docking of said piercing device with the inhalation device holding a reservoir allows said at least one perforator to access content of the reservoir, and wherein activation of said at least one heating mechanism allows generation of vapors from the content of the reservoir to be carried through at least one of said plurality of passages to a user.
    Type: Application
    Filed: June 27, 2018
    Publication date: December 27, 2018
    Applicant: Resolve Digital Health Inc.
    Inventor: Robert ADELSON
  • Publication number: 20180369519
    Abstract: The present disclosure relates to an inhaler having a container, wherein the container can include a plurality of chambers, each chamber of the plurality of chambers being filled with a liquid in a manner such that upon actuation of said inhaler, and based on selection of dosing parameter by a user, one or more liquids from respective chambers are retrieved and dispensed to said user through an opening.
    Type: Application
    Filed: June 26, 2018
    Publication date: December 27, 2018
    Applicant: Resolve Digital Health Inc.
    Inventor: Robert ADELSON
  • Publication number: 20180369520
    Abstract: A gas monitoring system for artificial ventilation includes: a sensor that is configured to produce a signal corresponding to a concentration of a predetermined gas in a portion which is in a respiratory circuit of an artificial ventilator, and through which both an inspiratory gas and an expiratory gas pass; a displaying apparatus that is communicable with the sensor; a processor; and a memory that is configured to store a command which is readable by the processor. When, during high-frequency oscillatory ventilation performed by the artificial ventilator, the command is executed by the processor, the processor is to configured to calculate a measurement value of the concentration based on the signal, and is configured to display at least one of a waveform corresponding to the signal and the measurement value on the displaying apparatus.
    Type: Application
    Filed: June 21, 2018
    Publication date: December 27, 2018
    Inventor: Toshiki AOKI
  • Publication number: 20180369521
    Abstract: A flow generator includes a housing, a blower structured to generate a flow of pressurized breathable air, and a suspension device to support the blower within the housing and provide a pressure seal between low and high pressure sides of the blower. The suspension device includes a bellows-like portion provided along the perimeter of the blower to absorb shock applied at least radially to the blower and one or more cones provided along upper and/or lower sides of the blower to absorb shock applied at least axially to the blower.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Inventors: Allan Freas VELZY, Samuel Aziz MEBASSER, Roman VINOKUR, Kevin Gene MCCULLOH, Michael David BEDNAR, Karl Yutaka IWAHASHI, David Brent SEARS, Peter Jeffrey THOMAS, Yeu-chuan HSIA, Hiroshi SUZUKI, Benjamin An Shing CHAO
  • Publication number: 20180369522
    Abstract: A respiratory treatment apparatus implements pressure delivery control settings by improved set-up procedures. In such an embodiment, a processor may automate setting of parameters for delivering a controlled flow of breathable gas. Data sets of pressure delivery parameter settings may be associated with one or more respiratory pathology indicators. The respiratory pathology indicators may each represent a different respiratory condition diagnosis. The processor may then prompt for an input of at least one of the respiratory pathology indicators. In response to the input, a particular set of pressure delivery parameter settings associated with the input respiratory pathology indicator may then serve as a basis for setting controls for delivering a controlled flow of breathable gas for respiratory treatment.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Applicant: ResMed Limited
    Inventors: David John Bassin, Glenn Richards
  • Publication number: 20180369523
    Abstract: A therapeutic vaporizer inhalation bag attachment system with an integrated valve is disclosed. The attachment system includes a body having a lumen extending between the two openings of the body, a bag coupling, and a valve positioned within the lumen. A method of using the inhalation bag attachment system is also disclosed.
    Type: Application
    Filed: June 29, 2018
    Publication date: December 27, 2018
    Inventors: Robert Irving Pratt, JR., Joshua Smith Young
  • Publication number: 20180369524
    Abstract: The invention relates to an ergonomic foot pedal and to apparatuses for manual ventilation. In an embodiment, the invention provides a compact and integrated foot pedal that enables a care provider to provide positive pressure ventilation to a subject's airways and lungs, and to optionally apply suction for the purpose of aspirating mucous, secretions, meconium, blood, fluids or other such materials from a patient—specifically from airways.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 27, 2018
    Applicant: SECRETARY, DEPARTMENT OF BIOTECHNOLOGY
    Inventors: Avijit BANSAL, Ayesha CHAUDHARY, Dinesh KUMAR, Sahaj GHOSE, Amit KUMAR
  • Publication number: 20180369525
    Abstract: An anesthesia ventilator, for the automated ventilation of a patient, includes an expiratory port and an inspiratory port for connecting a ventilation tube facing the patient for a breathing gas, a breathing gas delivery unit, at least one breathing gas sensor for detecting an anesthetic gas concentration, at least one pressure sensor for detecting a pressure of the breathing gas, as well as at least one computer. The computer is configured to actuate the breathing gas delivery unit as a function of the detected pressure of a preset desired pressure value. The computer is further configured to perform an adaptation of the desired pressure value as a function of the detected anesthetic gas concentration.
    Type: Application
    Filed: November 21, 2016
    Publication date: December 27, 2018
    Inventors: Wilfried BUSCHKE, Christoph HÖRMANN, Stefan MERSMANN
  • Publication number: 20180369526
    Abstract: An airway suction inlet port. The airway suction inlet port includes a housing having at least one sidewall defining an interior volume, wherein a port having a membrane thereacross is disposed on the sidewall. The port provides access to the interior volume, such that the membrane forms an airtight seal about a catheter inserted therethrough. An inlet is disposed on the housing, the inlet affixed to a bag-valve system such that air can be forced from the bag-valve system through the inlet. An outlet is disposed on the housing, the outlet capable of securing to an endotracheal tube. The catheter can then be fed through port and the outlet and into the endotracheal tube to provide suction internal to the endotracheal tube.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Inventors: Paul A. McGowan, Pamela Michelle McGowan Barker
  • Publication number: 20180369527
    Abstract: A speaking valve adapter is disclosed for assisting with speech or language expression during the respiratory recovery of a human. The speaking valve adapter including a speaking valve port, the port being orthogonal to a first interface port, the first interface port adapted to support tracheostomy or endotracheal tubing, a second interface port adapted to support at least one of a suction tubing and a bronchoscopy tubing, and a third interface port adapted to support a connection to a ventilator. The speaking valve adapter may be used by the patient for introduction of at least one of sounds and words while connected to the ventilator. A corresponding respiratory management system which implements the speaking valve adapter and configurable ventilator settings adapted for assisting with more effective speech or language expression during patient recovery or use is also disclosed.
    Type: Application
    Filed: August 3, 2018
    Publication date: December 27, 2018
    Inventor: Frank H. Arlinghaus, JR.
  • Publication number: 20180369528
    Abstract: A customized sealing member is for a customized mask. The customized mask includes a support member. The customized sealing member is manufactured by the process of generating surface geometry data of a face of a patient, the surface geometry data corresponding to and representing a surface geometry of the face of the patient; providing a directing apparatus shaped according to the surface geometry data, the directing apparatus being structured to receive and direct a stock of material; and inserting the stock of material into the directing apparatus in order to produce the customized sealing member.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 27, 2018
    Inventor: Elizabeth Powell Margaria
  • Publication number: 20180369529
    Abstract: A customized mask is manufactured by the process of: generating surface geometry data of a face of a patient, the surface geometry data corresponding to and representing a surface geometry of the face of the patient; generating original cushion geometry data using the surface geometry data; generating modified cushion geometry data using the original cushion geometry data; producing a rigid support member using the modified cushion geometry data such that it is shaped according to the modified cushion geometry data, the support member being made of a unitary material; and coupling a sealing flap to the support member, the sealing flap being structured to engage the face of the patient.
    Type: Application
    Filed: December 21, 2016
    Publication date: December 27, 2018
    Inventors: JONATHAN SAYER GRASHOW, LAUREN PATRICIA CHODKOWSKI
  • Publication number: 20180369530
    Abstract: A customized sealing member is for a customized mask of a pressure support system. The steps to manufacture the customized sealing member include generating surface geometry data of a face of a patient, the surface geometry data corresponding to and representing a surface geometry of the face of the patient; generating customization data using the surface geometry data, the customization data representing how a seal blank should be modified for the patient; and customizing the seal blank using the customization data such that the customized seal blank is shaped according to the customization data.
    Type: Application
    Filed: December 12, 2016
    Publication date: December 27, 2018
    Inventor: LAUREN PATRICIA CHODKOWSKI
  • Publication number: 20180369531
    Abstract: A portable oxygen concentrator designed for medical use where the adsorbent beds, are designed to be replaced by a patient. The concentrator is designed so that the power supply and adsorbent bed mount is one module and the compressor and air filter are part of another module configured to provide a unitary cooling and air supply system. Replacement beds may be installed easily by patients, and all gas seals will function properly after installation.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Inventors: Brenton Alan Taylor, Peter Hansen, John Russell Stump, Patrick Fitzlindon Burgess, Daniel Wayne Chin
  • Publication number: 20180369532
    Abstract: Oxygen concentrator apparatus and method of use are described herein. The oxygen concentration may include at least one canister; gas separation adsorbent disposed in at least one canister, and a compression system. The compression system may include at least one compressor coupled to the at least one canister. The compressor may include a first rotor comprising at least two projections and a second rotor comprising at least two recesses. During rotation of the first and second rotors, gas moves through the compressor to at least one of the canisters. In the canisters, gas separation adsorbent may separate at least some nitrogen from air produce oxygen enriched gas.
    Type: Application
    Filed: December 16, 2016
    Publication date: December 27, 2018
    Inventor: Dragan Nebrigic
  • Publication number: 20180369533
    Abstract: A breathing tube for a patient ventilator system providing humidified breathable gas is provided, the tube including inhalation and exhalation pathways formed in part by inhalation and exhalation tubes. A coupler member is attached at one end to the exhalation tube and forms part of the exhalation pathway, the coupler member has an integrated coupler-member electrical heating device electrically connected to the tube-portion electrical heating device. A connecting piece is detachably attachable to the other end of the coupler member and forms a part of the exhalation pathway, the connecting piece and coupler member together forming a hollow space therewithin extending from within the connecting piece to within the coupler member. A filter element is within the hollow space and extends from within the connecting piece into the coupler member, the coupler-member heating device is along the hollow space, surrounding the filter element, and adapted to heat the filter element.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Applicant: HAMILTON Medical AG
    Inventor: Rudolf BUECHI
  • Publication number: 20180369534
    Abstract: A resuscitator includes a flow control unit (5). The unit includes: (a) a peak inspirational pressure valve and controller (“PIP valve”) for controlling the pressure of gas delivered to the lungs of a patient, such as an infant, during inhalation so that the pressure does not exceed a selected PIP pressure, (b) a positive end-expiratory pressure valve and flow controller (“PEEP valve”) for allowing gas flow from the lungs through the PEEP valve during exhalation when the pressure in the lungs is above a selected PEEP pressure, and (c) a blow-off pressure relief valve that opens automatically if the gas pressure being delivered to the lungs exceeds a selected safe operation blow-off pressure that is higher than the selected PIP pressure.
    Type: Application
    Filed: November 10, 2016
    Publication date: December 27, 2018
    Inventor: Ian BIRD
  • Publication number: 20180369535
    Abstract: A breath powered positive airway pressure device having an expiratory chamber for receiving expired air from a user. The chamber has at least one resiliently flexible surface that is configured to expand to accommodate the expired air, so that the pressure within the chamber gradually increases during expiration. The device may also include an inspiratory chamber for holding air to be inspired, wherein the at least one resiliently flexible surface forms a flexible partition separating the expiratory chamber from the inspiratory chamber. The flexible partition is configured to expand into the inspiratory chamber during expiration, so that the air that is held within the inspiratory chamber also becomes pressurized during expiration.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 27, 2018
    Inventor: George VOLGYESI
  • Publication number: 20180369536
    Abstract: Methods, devices and systems for improving sleep (including reducing sleep onset and maintenance of sleep duration), enhancing, or increasing sleep, including (but not limited to) treating sleeping disorders such as insomnia.
    Type: Application
    Filed: July 26, 2018
    Publication date: December 27, 2018
    Inventors: Rick W. WALKER, Edward P.G. DOUGHERTRY, Jason A. BELTON, Robert E, TUCKER, Jeffrey J. SCHIRM
  • Publication number: 20180369537
    Abstract: Catheters, sheaths, or other tubular devices are provided that include a proximal end, a distal end sized for introduction into a patient's body, and a steerable distal portion carrying a plurality of electrodes. The tubular device includes a primary lumen extending between the proximal and distal ends; a steering element lumen adjacent the primary lumen; a plurality of wires extending proximally from the electrodes, and reinforcement members including windings extending helically along at least the distal portion, at least some of the windings passing between the primary and steering element lumens and wires, and at least some of the windings surrounding the primary lumen and one or both of the steering element lumen and the wires. In one embodiment, a steering element is slidably disposed within the auxiliary lumen. Apparatus and methods for making such tubular devices are also provided.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Inventors: Stephen A. Leeflang, Christian S. Eversull
  • Publication number: 20180369538
    Abstract: Provided is a catheter to be inserted into an object. The catheter includes a main body having a tubular shape and an expansion layer formed on an outer circumferential surface of the main body, and the expansion layer contains an expandable material which is expanded by contact with a liquid.
    Type: Application
    Filed: November 4, 2016
    Publication date: December 27, 2018
    Applicants: The Asan Foundation, AJOU University Industry-Academic Cooperation Foundation, University of Ulsan Foundation for Industry Cooperation
    Inventors: Deok Hee LEE, Ji Hoon SHIN, Seon Moon HWANG, Tae Il KIM, Ga Young LEE, Eun Joung KIM, Jin Ho YOON, Seng Yong CHUN, Ki Dong PARK, Yun Ki LEE
  • Publication number: 20180369539
    Abstract: A biologics delivery device and method of use for promoting angiogenesis in occluded vessels and ischemic tissue of a patient are provided, wherein the biologics delivery device includes a catheter having a proximal end, a distal region having a distal end, and a side wall defining a catheter lumen; an expandable member disposed in the distal region, the expandable member configured to support a subintimal space in an occluded blood vessel of a patient, and to transition between a collapsed state and an expanded state; and a hollow needle having a penetration tip deployable from inside the catheter lumen to outside the catheter lumen, and into tissue surrounding the occluded blood vessel, wherein the expandable member in the expanded state allows the flow of oxygenated blood to the occluded blood vessel. Methods of using the inventive biologics delivery device also are provided to deposit the biologic from a subintimal space to tissue surrounding the occluded blood vessel.
    Type: Application
    Filed: August 29, 2018
    Publication date: December 27, 2018
    Inventors: Krishna ROCHA-SINGH, Krishna MARTINEZ-SINGH
  • Publication number: 20180369540
    Abstract: A catheter assembly includes: a catheter; a catheter hub connected to the catheter; an inner needle removably disposed in the catheter; a needle hub connected to the inner needle; and a deflection suppressing member that suppresses deflection of the inner needle by supporting the inner needle via the catheter at a location distal of the catheter hub. The deflection suppressing member is supported so as to be movable relative to the needle hub in an axial direction.
    Type: Application
    Filed: August 14, 2018
    Publication date: December 27, 2018
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Toshiya ASAI
  • Publication number: 20180369541
    Abstract: A method for measuring a distance in a body vessel and introducing an implant into the body vessel, the method comprising: providing a guide wire, wherein the guide wire comprises a proximal end and a distal end, wherein the distal end comprises a spiral which has at least two adjoining spiral sections as markings, wherein at least a surface of one spiral section comprises a first material and at least a surface of the second spiral section comprises a second material, and further wherein the first material is different than the second material; inserting the guide wire into the body vessel; measuring the distance in the body vessel using the markings on the guide wire; and delivering the implant over the guide wire to the body vessel.
    Type: Application
    Filed: April 13, 2018
    Publication date: December 27, 2018
    Inventor: Michael Braun
  • Publication number: 20180369542
    Abstract: A guide wire is disclosed, the guide wire including a flexible wire main body, a coil that is intermediately disposed in a longitudinal direction of the wire main body in an outer periphery of the wire main body, and a support portion that supports at least one of a distal end and a proximal end of the coil so as to be rotatable around a central axis O of the wire main body. In a natural state where an external force is not supplied to the guide wire, the support portion supports in a state where an inner peripheral portion of the coil and an outer peripheral portion of the wire main body are separated from each other.
    Type: Application
    Filed: August 3, 2018
    Publication date: December 27, 2018
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Jo FUJIKI
  • Publication number: 20180369543
    Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 27, 2018
    Inventors: Angela Susan CRALL, Scott Lee RANDALL, Robert RIGHI, Sean WALL
  • Publication number: 20180369544
    Abstract: A system for supporting or dilating a body vessel includes a balloon catheter with a shaft having a delivery lumen in communication with an interior of the balloon. The balloon includes holes formed in the outer wall of the balloon. Additional or daughter balloons are delivered through the delivery lumen into the cavity of the balloon and through the holes into engagement with the holes. The daughter balloons are inflatable to seal against the holes, and the main balloon is subsequently inflatable when sealed by the daughter balloons. The daughter balloons may be delivered to branch vessels to provide support in addition to the inflation of the main balloon. The system may include preloaded wires extending through the delivery lumen and through the holes, and the daughter balloons can be delivered over the wires to the desired location.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 27, 2018
    Applicant: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Blayne A. Roeder
  • Publication number: 20180369545
    Abstract: A system for providing lumen support and dilation includes a balloon catheter having an inner balloon and an outer mesh bonded to the shaft, with the mesh surrounding the inner balloon and defining an intermediate space therebetween. The mesh may have holes formed in an outer wall, with the inner balloon being free from holes. The shaft includes a delivery lumen in communication with the intermediate space. Daughter balloons are deliverable into the intermediate space through the delivery lumen and into engagement with holes formed in the mesh, where the daughter balloons are inflated and retained by the holes of the mesh. The catheter may include one or more preloaded wires extending through the delivery lumen and into the intermediate space and through the holes, such that the daughter balloons are deliverable over the wires into the corresponding hole.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 27, 2018
    Applicant: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Elizabeth A. Eaton
  • Publication number: 20180369546
    Abstract: A system for providing dilation and support to a body vessel includes a shaft having two compliant balloons attached to the shaft and spaced apart longitudinally from each and defining a longitudinal intermediate space between them. The shaft includes an inflation lumen for inflating the balloons and a delivery lumen for delivering secondary balloons into the intermediate space. The shaft includes side-ports that provide communication from the delivery lumen. Secondary balloons are deliverable over wires that extend through the delivery lumen and out of the side-ports, with the secondary balloons delivered through the side ports and to a desired location and inflated in the intermediate space or adjacent the intermediate space, such as to branch vessels. The compliant balloons are inflatable toward each other to take up the intermediate and conform to the shape of the body vessel and the secondary balloons.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 27, 2018
    Applicant: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Elizabeth A. Eaton
  • Publication number: 20180369547
    Abstract: A medical balloon for a balloon catheter is described. The balloon has at least a first layer made from a first material and a second layer made from a second material, said first and second layers being in overlying relationship with one another and being integral with one another; wherein the first layer has a softening or melting temperature which is higher than a softening or melting temperature of the second layer. A method of forming the medical balloon is also described, including locating a raw tubing in a mold; preheating and inflating the raw tubing so as to cause it to stretch; heating the raw tubing to soften or melt the second layer; setting the inflated raw tubing to form the medical balloon; and cooling the set balloon.
    Type: Application
    Filed: August 29, 2018
    Publication date: December 27, 2018
    Applicant: Cook Medical Technologies LLC
    Inventors: David A. Drewes, Steen Aggerholm, Tue Thuren Bödewadt, Thomas Lysgaard
  • Publication number: 20180369548
    Abstract: A system for providing lumen support and dilation includes a balloon catheter having an inner balloon and an outer balloon bonded to the shaft, with the outer balloon subsuming the inner balloon and defining an intermediate space therebetween. The outer balloon may have holes formed in an outer wall, with the inner balloon being free from holes. The shaft includes a delivery lumen in communication with the intermediate space. Daughter balloons are deliverable into the intermediate space through the delivery lumen and into engagement with holes formed in the outer balloon, where the daughter balloons are inflated and retained by the holes of the outer balloon. The catheter may include one or more preloaded wires extending through the delivery lumen and into the intermediate space and through the holes, such that the daughter balloons are deliverable over the wires into the corresponding hole.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 27, 2018
    Applicant: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Elizabeth A. Eaton
  • Publication number: 20180369549
    Abstract: Methods and devices are provided for inhibiting nerves when activating brown adipose tissue (BAT). In general, a first nerve type (e.g., sympathetic nerves) innervating BAT can be activated while at least one other nerve type (e.g., parasympathetic nerves and/or sensory nerves) innervating BAT is being suppressed. A first neuromodulator (e.g., an electrical signal, a chemical, a light, cooling, etc.) can be applied to activate the first nerve type, and a second neuromodulator can be applied to inhibit the at least one other nerve type. In this way, parasympathetic nerves and/or sensory nerves innervating BAT can be inhibited when activating sympathetic nerves innervating BAT.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 27, 2018
    Inventors: Jason L. Harris, Tamara C. Baynham
  • Publication number: 20180369550
    Abstract: A steam therapy equipment including a vessel for heating a mixture of water and organic materials, a compressor to inject pressurized air into the vessel producing pressurized steam. The pressurized steam is conducted into the equipment via one or more valves. The therapy equipment is formed from at least one panel and may include a supporting frame. The therapy equipment includes a temperature sensor to measure the temperature inside the therapy equipment when pressurized steam is admitted via the valves. A patient enters the equipment and is exposed to the pressurized steam, causing dilation of the skin pores of the patient, whereby toxins are removed from the patient. One or more applicators may conduct pressurized steam to specific portions of the body of the patient. The patient may be provided with a portion of the mixture to consume as part of the steam therapy treatment.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Inventor: Basil C. Ogbu
  • Publication number: 20180369551
    Abstract: A steam therapy equipment including a vessel for heating a mixture of water and organic materials, a compressor to inject pressurized air into the vessel producing pressurized steam. The pressurized steam is conducted into the equipment via one or more valves. The therapy equipment is formed from at least one panel and may include a supporting frame. The therapy equipment includes a temperature sensor to measure the temperature inside the therapy equipment when pressurized steam is admitted via the valves. A patient enters the equipment and is exposed to the pressurized steam, causing dilation of the skin pores of the patient, whereby toxins are removed from the patient. One or more applicators may conduct pressurized steam to specific portions of the body of the patient. The patient may be provided with a portion of the mixture to consume as part of the steam therapy treatment.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Inventor: Basil C. Ogbu
  • Publication number: 20180369552
    Abstract: A transdermal delivery device comprising a roller, at least one microneedle supported by the roller, and at least one reservoir for a liquid pharmaceutical composition; wherein movement of the roller over the skin of a patient will cause it to rotate and bring the at least one microneedle into contact with the skin of the patient and to bring the at least one microneedle into fluid communication with the at least one reservoir. A method of assembling a transdermal delivery device comprising attaching the at least one microneedle to the device and attaching the at least one reservoir to the device. A method of administering a liquid pharmaceutical composition to a patient using a transdermal delivery device.
    Type: Application
    Filed: January 24, 2017
    Publication date: December 27, 2018
    Applicant: NDM TECHNOLOGIES LIMITED
    Inventors: Dewan Fazlul Hoque CHOWDHURY, Waqas Akbar LUGHMANI, Savvas VOULGARIS
  • Publication number: 20180369553
    Abstract: A microneedling machine for tattooing is disclosed, which has a substantially radially symmetric exterior shape and may include subcomponents that can be disassembled and sterilized. The machine may include an adjustment mechanism for configuring the impact of the microneedle into skin. The machine may also include a motion translation device adapted to change rotational motion of the drive shaft or motor into linear reciprocating motion of the microneedle.
    Type: Application
    Filed: August 29, 2018
    Publication date: December 27, 2018
    Inventor: GASTON SICILIANO
  • Publication number: 20180369554
    Abstract: A patient may be treated by implanting a combined arterial venous fistula graft implant in a limb of the patient. The combined implant includes a body with a vessel segment in contact with an artery and a first tubular segment for attachment to an end of a vein to form an arterial venous fistula, and a second tubular segment with an attached segment of artificial tubing for attachment to the vein at a second location to form an arterial venous graft. The arterial venous graft may be exclusively used to form hemodialysis for a period of time after the implanting step, while the arterial venous fistula matures.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 27, 2018
    Inventors: Barrett Davis, Kalub Hahne