Abstract: A sample cell (10) for a respired gas sensor has a single-piece injection molded main body (40) defining a gas flow path including an optical sampling bore (42), a gas inlet lumen (50) connected with the inlet end (44) of the optical sampling bore, and a gas outlet lumen (52) connected with the outlet end (46) of the optical sampling bore. The gas flow path includes at least two curved walls (100, 102, 104, 106). The sample cell may be manufactured by assembling mold pins (120, 122, 124, 126, 128) for defining the gas flow path wherein at least two mold pins (122, 124) have curved surfaces for defining the at least two curved walls of the gas flow path, and injection molding the single piece injection molded main body including removing the mold pins after defining the gas flow path including the at least two curved walls.

Abstract: A sensor-based quantification and analysis system includes an input device including a plurality of sensors that generate an input based on a force. The input device also includes a transmission device that transmits force information based on the input. The system also includes an output device that receives the force information. A processing unit selects, for each of the plurality of sensors, one of a plurality of levels of a likelihood of tissue damage based on the force and a predetermined time period. Further, the output device includes a display that presents or logs the one of the plurality of levels of the likelihood of tissue damage for each of the plurality of sensors.

Abstract: The Vaginal Canal Measurement Device is the only product of its kind to give an accurate evaluation of women's vaginal opening without the need for doctor to patient contact or guessing. The Vaginal Canal Measurement Device is uniquely designed to be a single-use product, to minimize exposure to bacteria.

Abstract: This relates to systems and methods for determining the axial orientation and location of the user's wrist using one or more sensors located on the strap, the device underbody, or both. For example, the strap can include a plurality of elastic sections and a plurality of rigid sections. Each elastic section can include one or more flex sensors. In some examples, on or more electromyography (EMG) sensors can be included to measure the user's electrical signals, and the user's muscle activity can be determined. In some examples, a plurality of strain gauges can be included to generate one or more signals indicative of any changes in shape, size, and/or physical properties of the user's wrist. In some examples, the device can include a plurality of capacitance sensors for increased granularity and/or sensitivity in measuring the amount of tension exerted by the user's wrist.

Abstract: An analyte sensing device and a mobile device incorporating an analyte sensing device are disclosed. One example of an analyte sensing device is disclosed to include a body, a sensor die, and a substantially transparent material positioned such that the sensor die is sandwiched between the body and the substantially transparent material. The sensor die may be in optical communication with the substantially transparent material and in electrical communication with the body.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.

Abstract: A system to measure sweat vapor may include a skin contact sensor, a sweat vapor sensor, and a processor. The skin contact sensor may be configured to measure one or more aspects indicative of whether the measuring device is in contact with skin of a user of the measuring device. The sweat vapor sensor may be configured to measure one or more properties of sweat vapor of the user; and the processor may be communicatively coupled to the skin contact sensor and the sweat vapor sensor. The processor may be configured to confirm operation of the measuring device based on the one or more aspects measured by the skin contact sensor, and the sweat vapor sensor receiving the sweat vapor.

Abstract: A method of initializing a sensor with a voltage sequence including a ramped voltage combined with a biphasic voltage pulse. The initialization scheme results in faster in-vitro sensor run-in and stabilization times. In various examples, the in-vitro sensor stabilization time is reduced from 200 minutes to 40-55 minutes (a reduction by a factor of least 5 as compared to a non-initialized sensor). In addition, staircase voltage initialization is implemented adaptively so that the voltage step size and sweep rates are changed depending on the state of the sensor (characterized by ISIG magnitude). As a result, individual sensors can be initialized in a customized manner rather than by using a general hardwired and harsh initialization scheme.

Abstract: An ophthalmic lens with glucose sensitive pad to indicate body glucose levels by changing color when in contact with tears from the eye includes a matrix, the matrix comprising a contact surface, the contact surface defining a micro-channel; and at least one glucose sensitive pad received in the micro-channel. A method for manufacturing an ophthalmic lens with glucose sensitive pad is also provided.

Abstract: Embodiments for synchronous communication between devices in an analyte monitoring system are disclosed. The devices can be in on body device having an analyte sensor and a reader device. The devices can communicate with each other over one or more wireless links. Systems, devices, and methods for establishing synchronization, maintaining synchronization, and reestablishing synchronization are disclosed.

Abstract: Embodiments of the invention are directed to biosensors comprising one or more encapsulated functionalized domains, where the encapsulating matrix acts as the primary interface between the biosensor and the environment. Embodiments of the invention are directed to the fabrication of the biosensor.

Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.

Abstract: According to various embodiments, a medical system and method for early detection of shock may include devices configured to provide information about multiple patient parameters. In certain embodiments, the system may receive input from a regional saturation sensor. Based on these inputs, the system may provide a diagnosis of shock and/or distinguish between various types of shock.

Abstract: Some embodiments described herein relate to a sensor that includes a first a first polymer-luminescent sensing compound configured to produce a first luminescent signal in the presence of a first analyte and a second polymer-luminescent sensing compound configured to produce a second luminescent signal in the presence of a second analyte. The second luminescent signal can have a luminescent lifetime that is at least 1.1 times greater than a luminescent lifetime of the first luminescent signal. Such temporally differences in signal can be used to deconvolute the first luminescent signal from the second luminescent signal even when, for example, the first luminescent signal and the second luminescent signal have the same or a similar emission spectrum.

Abstract: Disclosed herein are devices, apparatus, systems, methods and kits for collecting and storing a fluid sample from a subject. A device for collecting the fluid sample can include a housing comprising a recess having an opening, a vacuum chamber in the housing and in fluidic communication with the recess, and one or more piercing elements that are extendable through the opening to penetrate skin of the subject. The vacuum chamber can be configured for having a vacuum that draws the skin into the recess. The recess can be configured having a size or shape that enables an increased volume of the fluid sample to be accumulated in the skin drawn into the recess.

Abstract: A needle assembly is disclosed. The needle assembly includes a housing having a flash chamber, and having a distal end and a proximal end engageable with a specimen collection container. The assembly includes a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior. The patient end of the cannula projects at least partially from the distal end of the housing, and the cannula interior is in fluid communication with the flash chamber. The assembly further includes a shield restrainably engaged with a portion of the housing and axially transitionable over the patient cannula from a retracted position in which the patient end is exposed, to an extended position in which the patient end is shielded by at least a portion of the shield, wherein at least a portion of the flash chamber is visible in the retracted position.

Abstract: Provided is a blood collection unit suitable for accelerated blood coagulation of whole blood for subsequent autologous or allogeneic use. The blood collection unit includes an inside surface that an activation site accelerating coagulation by having a high roughness. Further provided is a blood collection unit including an inside surface that has an activation site having a high roughness area, and an interior of the blood collection unit has been prepared with a pressure of no more than 255 mBar, and preferably a pressure of no more than 130 mBar.

Abstract: There is provided a system (100) for assessing delirium in a subject. The system includes a neural activity assessment module (102) for assessing neural activity data associated with the subject. The system also includes a delirium cause assessment module (104) for assessing data relating to at least one factor of a plurality of factors which contribute to the cause of delirium. The system also includes an intervention determination module (106) for determining, based on the assessment performed by the delirium cause assessment module, at least one intervention for reducing the contribution made by the at least one factor. A computer-implemented method and an apparatus are also disclosed.

Abstract: Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate, severe, or moderate to severe traumatic brain injury (TBI), using cTnI. Also disclosed are methods for determining whether to perform a head computerized tomography on a subject by detecting levels of cTnI. Finally, also disclosed are methods of outcome in subjects suffering from a mild TBI.

Abstract: A wearable electronic device may include a device body and a device band coupled to the device body for securing the device to a wrist of a user. The wearable electronic device may also include a wrist biometric sensor carried by one of the device body and the device band. The wrist biometric sensor may include biometric sensing pixels. The wearable electronic device may also include a processor coupled to the wrist biometric sensor and configured to cooperate with the biometric sensing pixels to acquire skin texture pattern images from adjacent portions of the user's wrist, and perform at least one authentication function based upon the skin texture pattern images.

Abstract: An apparatus for evaluating the tongue strength and coordination of a subject includes an intermediate device such as a lever which is pivotably attached to a coupling device and extends into a cavity of a nipple element. The lever is detached from the nipple and pivotable in response to deformation of the nipple element by a tongue force exerted on the nipple element by a subject during a suck-swallow-breathe sequence. The coupling device includes a sensing device to wirelessly transmit sensor outputs to a mobile device paired to the sensing device. The sensing device includes at least one sealed chamber defined by a membrane and a sensor. In one example, a first membrane and sensor senses pressure change in a fluid in the apparatus, and a second membrane and sensor is actuated by the intermediate device to sense deformation of the nipple element. A method using the apparatus is provided.

Abstract: Some embodiments include a system and method of analyzing and providing a patient's spinal alignment information and therapeutic device data. In some embodiments, the system and/or method can obtaining initial patient data, and acquire spinal alignment contour information. In some embodiments, the system and/or method can assess localized anatomical features of the patient, and obtain anatomical region data. In some embodiments, the system and/or method can analyze the localized anatomy and therapeutic device location and contouring. In some embodiments, the system and/or method can output localized anatomical analyses and therapeutic device contouring data on a display.

Abstract: A method of providing audio feedback in response to a user performance using an earpiece includes steps of identifying a manual work operation to be performed by the user, wherein the identifying the manual work operation is performed by the earpiece, monitoring performance of the manual work operation by the user, wherein the monitoring the performance of the work operation is performed by the earpiece, generating 3D sound cues at the earpiece to assist in the performance of the manual work operation by the user, and outputting the 3D sound cues to the user at one or more speakers of the earpiece during the performance of the manual work operation by the user.

Abstract: A system comprising: a wrist-worn device configured to be worn on the wrist of a rescuer performing cardiopulmonary resuscitation (CPR), the wrist-worn device including: one or more sensors coupled with the wrist-worn device, the one or more sensors being configured to sense one or more parameters indicative of a fatigue level of the rescuer; and a sensor interface configured to provide the sensed parameters to one or more external computing devices via an interface; and a wearable computing device configured to be worn by a rescuer, the wearable computing device including: a device interface for receiving information related to CPR; and a display for displaying an indication of the received information.

Abstract: A method of determining sleep statistics for a subject includes the steps of: collecting cardio-respiratory information of the subject; extracting features from the cardio-respiratory information; determining sleep stages of the subject by using at least some of the extracted features; determining an estimated total sleep time of the subject based on the determined sleep stages; and determining sleep statistics of the subject using the estimated total sleep time.

Abstract: Objective Pulmonary Function (PF) evaluation for respiratory fatigue is vital to the diagnosis and management of many pediatric respiratory diseases in the intensive care, emergency and outpatient settings. A non-invasive PF instrument utilizes sensors and software to access respiratory breathing patterns, vital parameters, asynchrony and measures the work of breathing. Software algorithms predict respiratory fatigue. The hardware includes a microcircuit board that individually links to rib cage (RC) and abdominal (ABD) inductance bands. The bands wirelessly transmit changes in RC and ABD circumference. Point-of-care, real-time indices of respiratory work, breathing patterns and respiratory fatigue indices are developed on a user-friendly graphical user interface. The diagnostic data can later be securely emailed as an attachment for entry into patients' electronic medical records or sent to a caretaker's computer, or used directly to control a respiratory therapy device.

Abstract: Various embodiments of the present technology generally relate to a single monolithic IC to perform simultaneous optogenetic neural inhibition and extracellular electrophysiological recording in-vivo. Some embodiments include a low input capacitance (e.g., 9.7 pF) amplifier particularly tailored for the use of high-impedance electrodes to conduct single neuron extracellular recording integrated with programmable high current drivers for optogenetic stimulation or inhibition on the same IC chip. Some embodiments use a noise model to guide the IC design process to obtain parameters for optimal signal-to-noise ratio. The performance of the IC chip was demonstrated on an anesthetized gerbil expressed with inhibitory optogenetic protein (Halorhodopsin). Spontaneous action potentials from the fifth nerve of the brainstem were recorded by the amplifier and were subsequently inhibited by laser illumination.

Abstract: Methods, systems, and apparatus for assessing a state of an epilepsy disease or a comorbidity thereof are provided. The methods comprise receiving at least one autonomic index, neurologic index, stress marker index, psychiatric index, endocrine index, adverse effect of therapy index, physical fitness index, or quality of life index of a patient; comparing the at least one index to at least one reference value; and assessing a state of an epilepsy disease or a body system of the patient based on the comparison. A computer readable program storage device encoded with instructions that, when executed by a computer, perform the method described above is also provided. A medical device system capable of implementing the method described above is also provided.

Abstract: Methods and apparatus for determining the efficacy of a drug by diagnosing cardiovascular health in a patient by monitoring changes in skin redness levels, which is associated with perfusion and ability of circulatory system to adapt to physical exertion. Color detectors including colorimeters and spectrophotometers may be used to monitor and quantify skin color. Wet run solutions such as acetylcholine solutions may be applied to the skin area being monitored. Skin redness can be monitored during the course of exercise or a stress test, as well as during recovery. Wearable color detector devices can be worn by patients during exercise.

Abstract: Disclosed herein a system and a method to detect an amputee's hand muscles movements for controlling an artificial limb prosthesis. The system may comprise a plurality of passive tag positions and wearable band with a plurality of on-board position readers. The plurality of on-board position readers may be configured to capture data associated with a first plurality of passive tags positions at a first moment, and capture data associated with a second plurality of passive tags positions at a second moment. The system may further include one or more processors configured to detect at least one of the muscle contraction, the muscle relaxation, and the muscle inactivity based on the data captured at the first moment and at the second moment, and thereby control the artificial hand prosthesis movements responsive to detection at least one of the muscle contraction, the muscle relaxation, and the muscle inactivity.

Abstract: System and method for analyzing components of one or more items at a time based on the analysis of image data and item component data and deciphering that data for the user. A user can use a computing device for item data input and the system recognizes or identifies items by image recognition, optical character recognition, voice recognition, typed query, barcode scan or a combination of those to analyze the item and return analysis of each item to the user's computing device through visual display, audible communication or a combination of both visual display and audible communication. System and method for analyzing items, recognizing or identifying the images of items, and analyzing the components of items is executed by referencing image databases, image recognition services, application program interfaces (APIs) and through machine learning to provide the user with analysis of items by processing the data that corresponds with those items.

Abstract: Devices, methods, computer-readable media, and systems for determining an identity of a food are disclosed. For example, a method may receive at least one property of at least one component in a sample of a food from an intra-oral device including a spectrometer, the at least one property obtained via the spectrometer, compares the at least one property to a plurality of food signatures, and determines the identity of the food based upon the comparing. In another example, a system may include an intra-oral device and a wireless device. The intra-oral device may include a spectrometer for measuring at least one property of at least one component in a sample of a food. The wireless device may include a processor for receiving the at least one property, comparing the at least one property to a plurality of food signatures, and determining the identity of the food based upon the comparing.

Abstract: A method of determining data model for use in predicting a state of a user based on collected biometric data collected via a sensor platform, the method comprising receiving from sensors of the sensor platform a plurality of the biometric data; extracting a plurality of representative features from the plurality of biometric data; receiving a plurality of user affect parameters associated with the plurality of representative features; correlating the plurality of user affect parameters with the plurality of representative features to determine a set of representative feature-affect pairings for the data model as a plurality of model data parameters; and storing the data model for subsequent use in determining the real time state of the user.

Abstract: The disclosure features adaptive sleeves that include a sensor, an electronic processor connected to the sensor, an adjustable voltage source connected to the electronic processor, and a sleeve formed of a fabric material and including one or more deformable elements attached to or embedded within the fabric material and connected to the adjustable voltage source, where during operation of the adaptive sleeve, the electronic processor is configured to apply a force to a portion of a body of a sleeve wearer in proximity to a contracted muscle in the wearer's body by receiving an input electrical signal from the sensor, and adjusting the voltage source to apply an output electrical signal to the one or more deformable elements, the output electrical signal having a magnitude that is correlated with a magnitude of the input electrical signal.

Abstract: A measurement apparatus (100) for measuring biological information by a measured part being contacted to a contact portion includes sensors (160, 170) that acquire biological measurement output from the measured part and a controller (180) that calculates a correction coefficient, for calculating the biological information, on the basis of the biological measurement output acquired by the sensors (160, 170) and calculates the biological information on the basis of the calculated correction coefficient and the biological measurement output acquired by the sensors.

Abstract: Provided are devices and methods suitable for immobilizing tissue and for use in non-invasive methods of assessing lower urinary tract symptoms as well as in surgical application.

Abstract: An apparatus capable of determining the force applied to the tip of an electrical impedance spectroscopy probe comprises: ?an elongate probe comprising a probe tip attached to a handle, the probe tip having a substantially planar distal end for contacting human or animal tissue; ?a load cell located in said handle and capable of measuring a force Floadcell applied axially along a longitudinal axis when said probe tip is in contact with said human or animal tissue; ?an accelerometer located in the handle for measuring a gravity vector Aaxial; ?processing means for compensating for the mass of the probe tip using said measured force and gravity vector to produce a calibrated measurement of force F applied to said probe tip.

Abstract: An information processing device, an information processing method, and a recording medium storing an information processing program. The information processing device and the information processing method include obtaining measurement data, accepting a specification of time in the measurement data as a specified time, reducing noise from the measurement data using each one of a plurality of methods, evaluating a result of noise reduction at the specified time, the noise reduction being performed using each one of the plurality of methods, and selecting one of the plurality of methods based on the evaluated result of noise reduction. The recording medium storing the information processing program for causing a computer to execute the information processing method.

Abstract: A method for creating a mother wavelet function. The method includes preparing a plurality of vectors, extracting a kernel from the plurality of vectors, and extracting the mother wavelet function from the kernel. The kernel includes a mode value of a vector of the plurality of vectors.

Abstract: The present invention relates to a device, system and a method for generating a photoplethysmographic image carrying vital sign information of a subject.

Abstract: An electronic blood pressure monitor includes: a vibration sensor that includes a film shape, the vibration sensor detecting vibrations of a body surface, the vibration sensor converting the detected vibrations to an electrical signal corresponding to pressure generated in a thickness direction of the vibration sensor to output the electrical signal; and a stethoscope filter that passes a signal of a first predetermined frequency band among the output electrical signal, the first predetermined frequency band being determined based on a frequency characteristic of a stethoscope.

Abstract: Circuits are provided for detecting an electrosurgical unit signal. An example circuit includes: a filter configured to process a floating ground signal associated with measuring a bio potential signal of a patient, and a detector configured to output a sensing signal based at least in part on the floating grounding and the Earth ground for detecting an electrosurgical unit signal.

Abstract: A physiological monitoring device is provided. The physiological monitoring device includes a physiological sensor, a quality estimator, and a feature extractor. The physiological sensor is configured to sense a physiological feature to generate a bio-signal. The quality estimator estimates quality of the bio-signal. The feature extractor receives the bio-signal and performs a predetermined operation to the bio-signal to obtain feature data. The amount of computation induced by the predetermined operation tier the feature extractor is changed according to the estimated quality of the bio-signal.

Abstract: The invention is an electronic sphygmomanometer that dynamically calibrates for a real-time standard blood pressure reference value, which is determined based on the objective condition of human blood pressure fluctuation influenced by various factors such as age, date and time of measurement, and establishes age/blood pressure reference value, date/blood pressure reference value and time/blood pressure reference. The value database, or through mathematical operations, obtains the real-time standard blood pressure reference value under the specific conditions of the subject's age, test date, and test time, and calibrates it as a benchmark for judging the abnormality state of the real-time blood pressure measurement value. This improves the ability of the sphygmomanometer in producing an accurate judgement of the subject's blood pressure, and reduces the margin of error for false positive tests or false negative tests.

Abstract: A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material.

Abstract: Disclosed are methods, apparatuses, and systems for performing physiological parameter signal fusion. By respectively analyzing a plurality of input physiological parameter signals, and obtaining a feature of each physiological parameter signal; according to the feature of each physiological parameter signal, obtaining and outputting a fusion state of the plurality of the physiological parameter signals; if the fusion state is a fusion of the at least two physiological parameter signals with the first physiological parameter signal is dominant, highlighting the first physiological parameter signal; and if the fusion state is a fusion of the at least two physiological parameter signals with the second physiological parameter signal is dominant, highlighting the second physiological parameter signal.

Abstract: A method and an apparatus for calculating a biometric index using biometric information are disclosed. An apparatus for calculating a biometric index using biometric information is provided, the apparatus comprising: a transmission/reception unit for receiving biometric information collected by a user terminal or a biometric information collection apparatus; a storage unit for storing an index calculation formula for calculating a biometric index and a daily body index using the biometric information and daily body index; an extraction unit for extracting the stored biometric information and index calculation formula; and a calculation unit for calculating a biometric index and a daily body index using the received biometric information and the predetermined index calculation formula, wherein the biometric index includes one or more of an eating behaviour index, an activity index, a sleep index and a heart rate variability index, and calculates the daily body index using the biometric index.

Abstract: A method of estimating oxygen saturation includes illuminating a target site with light of three different wavelengths, for example green, red and infrared, and detecting light returned from the site at each of the wavelengths. The method distinguishes between cardiac pulsatility and nonpulsatility based on a parameter of the return light of the shortest wavelength. The method formulates an estimate of oxygen saturation as a function of a parameter of the light of the two longer wavelengths taken at both a period of pulsatility and at a period of nonpulsatility. An oximeter adapted to carry out the method is also disclosed. Aspects of the method and oximeter may be used to estimate other physiological parameters.

Abstract: A physiological parameter display method may include: controlling the terminal to enter into one of multiple different working modes; obtaining a physiological parameter analysis result corresponding to the current working mode; and presenting corresponding output information according to the received physiological parameter analysis result, wherein the output information includes the received physiological parameter analysis result.