Abstract: A system for simulating surgical methods includes a method for thorax simulation modelling. The thorax simulation modeling is generally useful in facilitating the development and optimization of person specific surgical methods and materials.

Abstract: Methods and systems for providing feedback during a medical procedure. The 3D position and orientation of a tracked tool are determined, relative to a site of the medical procedure, based on tracking information received from a tracking system. The 3D position and orientation are mapped to a common coordinate space, to determine the 3D position and orientation relative to a field-of-view (FOV) of an optical camera that is capturing an optical image of the site. Navigational information associated with the 3D position and orientation is determined. A virtual representation of the navigational information overlaid on the FOV and displayed. The displayed virtual representation is updated when the 3D position and orientation of the tracked tool changes or when the FOV changes, in accordance with the change.

Abstract: Methods and systems for providing feedback during a medical procedure are provided. A saved optical image of a field of view (FOV) of a site of the medical procedure is obtained along with a live optical image of the FOV of the site during the medical procedure. Navigational information relative to the site of the medical procedure is determined. The navigational information is then mapped to a common coordinate space, to determine the navigational information relative to the FOV of the saved and live optical images of the surgical site. Virtual representations of the navigational information is overlaid on the saved and/or live optical images and displayed on at least one display.

Abstract: A method of compensating for motion of objects during a surgical procedure is provided. The method includes determining a pose of an anatomy of a patient; determining a pose of a surgical tool of a surgical device; defining a relationship between the pose of the anatomy and a position, an orientation, a velocity, and/or an acceleration of the surgical tool; associating the pose of the anatomy, the pose of the surgical tool, and the relationship; and updating the association in response to a motion of the anatomy and/or a motion of the surgical tool without interrupting operation of the surgical device during the surgical procedure.

Abstract: A surgical instrument for use with a robotic system that has a control unit and a shaft portion that includes an electrically conductive elongated member that is attached to a portion of the robotic system. The elongated member is configured to transmit control motions from the robotic system to an end effector.

Abstract: A snare tool manipulator system includes an elongated flexible device having a length and including a distally mounted end effector configured to perform a task. The flexible device is operable to manipulate the end effector in order to perform the task. The system also includes an elongated snare tool including a distally mounted snare device configured for grasping the flexible elongated member at a position along its length. The snare tool is operable robotically to manipulate the flexible device which in response manipulates the end effector.

Abstract: Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance are disclosed. According to an aspect, a system includes one or more controllers configured to receive an image dataset of an actual environment within which the robotic tool is positioned. The controller(s) are also configured to generate a virtual environment of the actual environment based on the image dataset. Further, the controller(s) can control display of the virtual environment including a virtual tool controllable by a user for use to control the robotic tool within the actual environment. The controller(s) can receive user input for altering a perspective view of display of the virtual environment from a first perspective view to a second perspective view. Further, the controller(s) can maintain orientation of display of the virtual tool with respect to the user during display of the first perspective view and the second perspective view of the virtual environment.

Abstract: A surgical system is provided comprising: an input device: and a controller for receiving control inputs from the input device and for providing haptic feedback at the input device, the controller configured to apply a staged transition from a first haptic feedback profile at the input device to a second haptic feedback profile at the input device.

Abstract: A surgical system is provided comprising: an input device; a first actuator and a second actuator; a controller for controlling the first actuator and the second actuator, the controller configured to apply a first scale factor to a first commanded output and a second commanded output for the first actuator the second actuator, respectively, when the first commanded output would fall outside a first predetermined working range of the first actuator, wherein the first scale factor adjusts the first commanded output to be within the first predetermined working range.

Abstract: A defibrillator storage device including a housing defining an interior storage compartment configured to hold a removable automated external defibrillator therein, a door pivotally attached to the housing, an alarm disposed within the housing, and a tether attached at a first end thereof to an interior wall of the housing and at a second end thereof to the alarm, the tether configured to be routed through a handle of the automated external defibrillator such that removal of the automated external defibrillator from the interior compartment causes the second end of the tether to be pulled from the alarm, thereby triggering the alarm.

Abstract: A medical kit (100) includes a package (105) having a housing (501) and a lid (103). One or more medical implements (1001,1101,1201,1301) for treating a skin tear wound are arranged in a stacked configuration within the package. An instructional labeling system (106) is coupled to the lid. The instructional labeling system can include an identification (107) of a skin tear type the one or more medical implements are designed to treat, a description (108) of the skin tear type, printed instructions (110) defining one or more steps (111,112,113,114) instructing when to use each medical implement within the package to treat the skin tear wound, and one or more removable adhesive labels (115,116).

Abstract: An endoscope includes: a rigid distal structure portion; a rotational portion; an exterior member; a bearing opposed to the exterior member and recessed from an outer surface of the distal structure portion, the bearing being; and a preventing portion. The bearing is configured to receive and support the rotational shaft and to displace the rotational shaft from the distal structure portion by the exterior member being removed from the distal structure portion. The preventing portion provided on one of the rotational portion and the distal structure portion, and configured to prevent disengagement of the rotational portion by coming in contact with the other of the rotational portion and the distal structure portion when the rotational shaft is displaced from the bearing.

Abstract: A station for tomotactic-guided biopsy in prone includes a table with an aperture, and a tomosynthesis imaging system. A biopsy gun can be mounted on a stage arm assembly disposed below the table. The imaging system and stage arm assembly can be independently rotated and linearly repositioned in one or more dimensions, thereby allowing the tomotactic scan axis to be located relative to a breast being imaged.

Abstract: The embodiments provide a surgical marking system for measuring and marking the location of various anatomical landmarks/bones on patient's skin before a surgical procedure. The system includes a shaft having a plurality of metallic markings and a radiographical pointer tip which is visible on fluoroscopic x-ray images. The shaft further includes a fluid reservoir for marking the location of an incision so that it is visible through fluoroscopic imaging technology and which provides a temporary marking agent that readily disappears after the surgical procedure has completed.

Abstract: A medical observation apparatus (10) includes an imaging section (140), an arm section (110), and a control section (210). The imaging section (140) captures an observation target. The arm section (110) includes multiple links and joint sections (130) that join the links to each other, and supports the imaging section (140). The control section (210) controls a torque that drives the joint sections (130). When a surgeon imparts an external force to the arm section (110) or the imaging section (140), a torque (external torque) due to the external force acts on the joint sections (130). When a torque detection section (134) of the joint sections (130) detects the external torque, the control section (210) outputs a torque command value (?) such that a joint driving section (131) produces a torque in the same direction as the external torque. The torque command value (?) includes a component that cancels out a torque that a cable (495) twisted inside the joint sections (130) produces due to a restoring force.

Abstract: A subassembly for a dental care or surgical handpiece comprises a push button (16) comprising a contact surface (23) adapted to receive a manual pressure able to actuate the push button (16) slidably in a sliding direction. This subassembly further comprises a piece (21) for retaining the push button (16), as well as a bayonet device (28a, 33, 35) able to keep assembled the push button (16) and the retaining piece (21).

Abstract: In an embodiment, an input indicating a location selected by a health care professional on an image rendered with respect to a viewport mapped onto an immersive photographic model of a patient's mouth to indicate a position to place an orthodontic bracket on a patient's tooth is received. A ray is extended from a focal point of the viewport at a direction determined based on the input. An intersection of the ray in a three-dimensional space is determined. The intersection indicates a position to place the orthodontic bracket on the patient's tooth.

Abstract: Arrangement includes a bracket having a pad and a bracket body having a slot for receiving an orthodontic wire, as well as, allocated to the bracket, a clip of a shape-memory material for closing and releasing of the slot of the bracket, for holding the orthodontic wire in a closing position in the slot, respectively to release it in an opening position for withdrawal from the slot. A first free end of the clip is a fixation end, which is rigidly connected to the bracket, and a second end of the clip is a free end which in the opening position lies against the bracket, releasing the slot, and in the closing position lies against the bracket, overlapping the slot.

Abstract: A system for scanning a dental arch of a patient includes a reference element having a reference pattern thereon; a holding mechanism configured to hold the reference element in a fixed position inside the patient's oral cavity adjacent to and spaced from the dental arch, wherein the holding mechanism is configured to be installed on the patient without contacting an occlusal surface of the dental arch; and an intra-oral scanner configured to scan the dental arch and an adjacent portion of the reference element to obtain a scanned image comprising the scanned portion of the dental arch and the scanned adjacent portion of the reference pattern.

Abstract: A dispenser for dispensing a liquid such as a tooth whitening gel can include a plunger and a housing having a first chamber that receives a first arm of the plunger and a second chamber that receives a second arm of the plunger. The housing can further include a first channel in fluid communication with the first chamber, a second channel in fluid communication with the second chamber, and a third channel formed at an intersection of the first and second channels. The housing can further include a static mixer than mixes a first liquid from the first chamber with a second liquid from the second chamber. The plunger may be disposed along a first axis and the third channel may be disposed along a second axis that intersects the first axis at an angle of between 10° and 170°.

Abstract: A teeth cleaning device for simultaneously cleaning multiple teeth, of a user includes a mouth insert for inserting into the mouth of the user, a plurality of cleaning structures attached to the mouth insert or integrally formed together with the mouth insert, a coupling element attached to the mouth insert; a drive device. The drive device includes a vibration motor, which can be connected to the coupling element such that the vibration motor vibrates the mouth insert during the operation of the teeth cleaning device, and a cleaning program selection element for selecting a cleaning program that defines a vibration frequency of the vibration motor within a specified frequency range and/or a vibration amplitude of the vibration motor within a specified amplitude range. The disclosure further relates to a method for producing such a teeth cleaning device.

Abstract: A toothbrush (10) includes a brushhead (18), a first force sensor (30A) for measuring a first force exerted by the brushhead at a first angle relative to a tooth and a second force sensor (30B) for measuring a second force exerted by the brushhead at a second angle relative to the tooth, the second angle being different than the first angle, and a processing unit (26). The processing unit is structured to: (i) receive first information indicative of the first force as measured by the first force sensor, (ii) receive second information indicative of the second force as measured by the second force sensor, and (iii) determine information regarding a current brushing angle of the brushhead based on the first information and the second information.

Abstract: A removable toothbrush head for an electric toothbrush includes a bristle carrier and an elongated neck. One end portion of the elongated neck includes an opening for connection to an electric toothbrush handle, and another end portion comprises a neck hub configured to rotatably support the bristle carrier. Also included is a driven brush shaft disposed longitudinally within the elongated neck. The brush shaft is configured to interact with the bristle carrier at a distal end portion of the brush shaft, which includes a pivot extension extending therefrom and spaced apart from the longitudinal axis of the brush shaft, as well as a bristle carrier interface positioned at least partially along the longitudinal axis of the brush shaft and configured to cause partial rotational motion of the bristle carrier when the brush shaft is driven by an electric toothbrush handle.

Abstract: A dental curing light includes a device body that efficiently conducts heat away from the light emitting diode portion of the curing light. The device body includes a proximal gripping end and a distal head end. The device body is formed from a thermally conductive body material. Excellent heat conduction away from the LED dies is achieved using a thermally conductive layer disposed over the device body. The thermally conductive layer serves as a conduit to quickly conduct heat away from the LED dies for dissipation within the material of the device body In this manner, the material of the device body serves as a highly efficient heat dissipater. The surface area coupling the thermally conductive layer to the device body is sufficiently large that a majority (e g, substantially all) of heat being conducted by the thermally conductive layer is transferred to the device body during operation of the device.

Abstract: The present disclosure relates to a phototherapy device that can deliver light to tissues to activate photoactive agents that have been applied to the tissues or that are included within a fiber optic tip member of the device which may be coupled to a light source using a sleeve. The present disclosure also relates to methods of phototherapy using the phototherapy device such as anti-bactericidal treatment, anti-fungal treatment, anti-parasitic treatment, anti-viral treatment.

Abstract: An implant adapted to treat urinary incontinence includes a support material, a suture, and an anchor. The support material is provided to support the urethra when implanted in a patient. The suture is inserted through the support material and includes a first trailing end portion and a second trailing end portion. The anchor has a body, a fin extending from the body with an eyelet formed in the fin and the suture passed through the eyelet of the fin, and a gripping tab removably attached to the fin. The gripping tab is removable from the fin prior to insertion of the anchor into tissue.

Abstract: A mechanical prosthetic heart valve assembly for the provision of surface anticoagulation by generating an electrostatic field of a plurality of negatively charged ions thereon, acting as neo-endothelium on the mechanical prosthetic heart valve, referred as Surface Anticoagulation by Electrical Neo-endothelialization (SAEN). The mechanical prosthetic heart valve assembly comprises a mechanical prosthetic heart valve housing; a pair of mechanical prosthetic heart valve discs; a mechanical prosthetic heart valve sewing ring; an implantable pulse generator serving as a source of electricity for generating the electrostatic field of the plurality of negatively charged ions thereon the surface of the mechanical prosthetic heart valve; a pulse generator bipolar lead connected to the outer surface of the mechanical prosthetic heart valve housing (102), using an electrode; and a polytetrafluoroethylene (PTFE) graft sutured to margins of a fenestration on the mechanical prosthetic heart valve sewing ring.

Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.

Abstract: A biodegradable device capable of producing a high radial force is described. Such a force will be created in devices made of relatively inelastic materials that are to be deployed to the vasculature or a body cavity in a patient. As the halves of the devices move together subject to a longitudinal force, at the point where they are in contact and unable to move closer together in the longitudinal direction, a radial force is created. The devices may have a tension element that assists in bringing the device halves together and which may partially and optionally remain within the body of the device.

Abstract: Methods are disclosed for forming tissue engineered, tubular gut-sphincter complexes from intestinal circular smooth muscle cells, sphincteric smooth muscle cells and enteric neural progenitor cells. The intestinal smooth muscle cells and neural progenitor cells can be seeded on a mold with a surface texture that induces longitudinal alignment of the intestinal smooth muscle cells and co-cultured until an innervated aligned smooth muscle sheet is obtained. The innervated smooth muscle sheet can then be wrapped around a tubular scaffold to form an intestinal tissue construct. Additionally, the sphincteric smooth muscle cells and additional enteric neural progenitor cells can be mixed in a biocompatiable gel solution, and the gel and admixed cells applied to a mold having a central post such that the sphinteric smooth muscle and neural progenitor cells can be cultured to form an innervated sphincter construct around the mold post.

Abstract: A prosthetic aortic root replacement graft for preserving the native aortic valve that includes a biocompatible flexible material having a) a tubular superior segment (3), with an upper free edge (2) for anastomosis of the prosthesis to the aortic arch, and a lower edge (4); b) a hollow medial segment (5) with an upper edge (6) that is connected to the lower edge (4) of the superior segment (3) and a lower edge (8); and c) optionally a tubular inferior segment (10). The medial segment (5) includes three triangular-like tongues (7) tapering towards the upper edge (6) and three bulges (12). The bulges (12) and the tongues (7) are in an alternating arrangement.

Abstract: Provided is a medical fabric that is thin, and has both high tear strength and low water permeability. The medical fabric is characterized in that multifilament yarns having a total fineness of 7-80 dtex are disposed in the warp and weft, the single yarn fineness of at least one of the multifilament yarns among the warp and weft is 0.5 dtex or less, the twist factor A of the weft is 50-2,000, the thickness is 10-90 ?m, and the water permeability both before and after puncture by a needle is 300 cc/min/cm2 or less.

Abstract: Various joint replacements are disclosed herein, as are methods of use thereof. The joint replacements can have a flexible band or multiple flexible bands that can link together a first part of the joint replacement and a second part of the joint replacement. The flexible band or bands can be tensioned to establish proper tension in the patient's joint. In certain circumstances, the joint replacement can be a shoulder joint replacement.

Abstract: A more versatile and anatomically correct breast implant is described. The breast implant comprises a container filled with a liquid or gel filling material and a support member coupled to the container, wherein the support member is an integral part of the container.

Abstract: A laminate useful as a component of a medical implant, for example, useful as a component of an inflatable tissue expander. The laminate includes a base layer, an intermediate layer, and a top layer. When used as a component of a tissue expander, the laminate enables an internal chamber pressure of about 2.5 psi with an expander exterior compressive force of about 40 lbs.

Abstract: A breast implant is provided which includes a filling, or core having a lower overall density relative to silicone gel-filled or saline-filled implant. The core may be a composite including flexible, bodies, for example, air-containing, or gas-containing, bodies, and a gel medium between or around the bodies.

Abstract: Prosthetic capsular devices (e.g., bag, bowl, housing, structure, cage, frame) include technology devices such as a computer, virtual reality device, display device, WiFi/internet access device, image receiving device, biometric sensor device, game device, image viewers or senders, GPSs, e-mail devices, combinations thereof, and/or the like. The technology devices can be used in combination with an intraocular lens. The output from the technology device(s) can be fed to the retina of the user to provide a visual image, can be otherwise connected to the user, and/or can be used to control the properties of the intraocular lens or of the prosthetic capsular device.

Abstract: An intraocular lens includes an annular housing coupled to a first window to form a lensing cavity. Disposed within the lensing cavity is two immiscible liquids, including a first liquid and a second liquid which form a meniscus at an immiscibility interface between the first liquid and the second liquid within the lensing cavity. The intraocular lens includes a flexible reservoir to store a variable portion of the first liquid. The flexible reservoir is disposed about at least a portion of a periphery of the annular housing. The intraocular lens also includes at least one channel linking the flexible reservoir to the lensing cavity to permit a transfer of the first liquid between the flexible reservoir and the lensing cavity. The transfer of the first liquid changes a curvature of the meniscus to adjust optical power of the intraocular lens.

Abstract: An exemplary valve repair device for repairing a native valve of a patient includes a pair of paddles, a coaption element, and a covering. The coaption element has a first end portion and a second end portion. The coaption element is connected to the pair of paddles. The covering is disposed over the caption element. The covering prevents blood from flowing through the caption element.

Abstract: An exemplary valve repair system for repairing a native valve of a patient during a non-open-heart procedure includes a delivery device and a valve repair device. The delivery device includes a catheter, an actuation shaft, and a coupler. The valve repair device is configured to be delivered through the catheter. The valve repair device is configured to attach to a native valve of a patient. The valve repair device includes a coaption element having a first end portion and a second end portion, a proximal collar attached to the first end portion of the coaption element, first and second paddles connected to the coaption element, and a distal collar connected to the first and second paddles. The coupler is releasably connected to the proximal collar. The actuation shaft extends through the coupler, the proximal collar, and the coaption element. The actuation shaft is releasably connected to the distal collar.

Abstract: An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis.

Abstract: A catheter is transluminally advanced to a heart of a subject. Via the catheter, a prosthetic valve is advanced to the native valve. The prosthetic valve includes an upstream skirt, and a downstream skirt that has a first portion and a second portion. The first portion defines a lumen therethrough. The second portion circumscribes the first portion, and defines a plurality of anchoring arms that are coupled to the second portion. A plurality of prosthetic leaflets, within the lumen, are attached to the first portion. The upstream skirt is expanded in the atrium, and the anchoring arms are expanded in the ventricle, the anchoring arms extending radially outward and toward the upstream skirt. Subsequently, native valve tissue is squeezed between the upstream skirt and the anchoring arms by causing the anchoring arms to move with respect to the prosthetic leaflets, and toward the upstream skirt.

Abstract: Some embodiments relate to Some embodiments relate to an integrated ultrasound guided delivery system for positioning or repositioning of a transcatheter heart valve including: a delivery catheter coupled to the transcatheter heart valve, and an intravascular ultrasound (IVUS) catheter operably coupled to the delivery catheter, wherein the IVUS catheter includes an ultrasound transducer tip that is aligned with a base of leaflets of the transcatheter heart valve. Also disclosed is a method for positioning or repositioning a transcatheter heart valve at a target site in a subject including: providing an integrated ultrasound guided delivery system as disclosed herein; advancing the transcatheter heart valve in the vicinity of a native valve, viewing the native valve and the target site in real-time with the IVUS catheter, and deploying the transcatheter heart valve at the target site aiming to maintain a conformal placement within the native valve annulus, thereby avoiding or minimizing paravalvular leak.

Abstract: A method for replacing a first sheath, whose distal end is positioned inside a vessel and whose proximal end is positioned outside the skin of a patient, with a second sheath may involve inserting a dilator over a guidewire and into the first sheath until a distal end of the dilator and a distal end of the guidewire are positioned inside the vessel. The dilator may be hubless or include a removable hub. The method may further involve removing the first sheath, thereby leaving only the dilator and the guidewire in place. After removing the first sheath, a second sheath may be passed over the dilator and the guidewire until the distal end of the second sheath is positioned inside the vessel. The method may further involve removing the dilator and the guidewire, leaving only the second sheath in place.

Abstract: Anchor assemblies for endovascular introduction and implantation for tethering a replacement heart valve to a cardiac wall. An anchor delivery system introduces the assembly. The anchor may be either implanted with a tether connected thereto or implanted and then connected to a tether. If the latter, a tether assembly is mounted to the implanted anchor to connect the anchor to the valve. The anchors may be implanted into any cardiac wall including the interventricular septum or the epicardial space and the valve may replace the mitral or tricuspid valve.

Abstract: Delivery devices for delivering a stented prosthesis to a target site are disclosed. Certain disclosed delivery devices include a handle assembly including an actuator, a shaft assembly interconnected to the handle assembly, and are configured to releasably retain the stented prosthesis to the delivery device with at least one elongate tension member. The delivery devices further include a torque shaft that is configured to apply and adjust the amount of tension in the each tension member. For example, the torque shaft can be configured to wind and unwind each elongate tension member around the torque shaft to correspondingly compress and expand the stented prosthesis. The torque shaft can be controlled with an actuator provided in the handle assembly, for example. In some embodiments, the actuator is further configured to axially move the torque shaft.

Abstract: An exemplary valve repair device for repairing a native valve of a patient has a paddle frame, an inner paddle, and an outer paddle. The outer paddle is connected to the inner paddle. The inner and outer paddles are connected to the paddle frame at a connection between the inner paddle and the outer paddle. A portion of the inner paddle is moveable away from a portion of the outer paddle to open the inner and outer paddles.

Abstract: In an exemplary method of implanting a valve repair device on a mitral valve of a patient, first and second clasps of the valve repair device are closed to grasp the leaflets of the mitral valve. First and second paddles of the valve repair device are closed to bring the leaflets of the mitral valve into contact with a coaption element.

Abstract: A kit for deploying a bone implant at a surgical site is provided. The kit comprises a first sleeve having an interior surface that defines a channel, and a second sleeve having an outer surface and an inner surface. The inner surface of the second sleeve defines an inner channel. The outer surface of the second sleeve is configured to slidably engage the interior surface of the channel of the first sleeve. A bone implant is also provided comprising a mesh material. The mesh material is disposed in a portion of the channel of the first sleeve or disposed in a portion of the inner channel of the second sleeve or disposed in both the portion of the channel of the first sleeve and the portion of the inner channel of the second sleeve, such that sliding the outer surface of the second sleeve deploys the bone implant at the surgical site. Bone implants and methods of implantation are also provided.

Abstract: Mould and method for realizing a temporary prosthesis of hip or shoulder, which comprises a shaft and a head. The mould comprises: a first mould portion (1) comprising a first half-shell (2); a second mould portion (3) comprising a second half-shell (4); the first mould portion (1) and the second mould portion (3) being able to be coupled with respect to each other so that the first and second half-shell (2, 4) are counter-faced and define a chamber (5) which conforms a shaft portion (5a), a head portion (5b) and an opening (5c) for injection of a fluid (preferably viscous) material; fixing means (6) for fixing the first and the second portion (1, 3); a first insert (7) comprising a cap portion (8) which is realized as a unique body, is dimensioned to be inserted in the head portion (5b) and is conformed to give shape to the head of the prosthesis.