Abstract: A spectroscopy system includes a light source having an input light source, including semiconductor diodes generating an input beam with a wavelength shorter than 2.5 microns. Cladding-pumped fiber amplifiers receive the input beam and form an amplified optical beam having a spectral width. A nonlinear element broadens the spectral width of the amplified optical beam to 100 nm or more through a nonlinear effect forming an output beam that is pulsed. A filter is coupled to at least one of a lens and a mirror that receives the output beam and delivers the filtered output beam to a sample. A detection system includes detectors configured to receive the output beam reflected or transmitted from the sample. The detection system is configured to use a lock-in technique with the pulsed output beam and the spectroscopy system is adapted to detect chemicals in the sample.

Abstract: A spectrometer includes a support having a bottom wall part in which a depression including a concave curved inner surface and a peripheral part adjacent to the depression are provided, and a side wall part disposed on a side on which the depression is open with respect to the bottom wall part, a light detection element supported by the side wall part while opposing the depression, and a dispersive part disposed on the inner surface of the depression. A length of the depression in a second direction in which a plurality of grating grooves included in the dispersive part is aligned is larger than a length of the depression in a third direction orthogonal to the second direction when viewed in a first direction in which the depression and the light detection element oppose each other. An area of the peripheral part adjacent to the depression in the second direction is larger than an area of the peripheral part adjacent to the depression in the third direction when viewed in the first direction.

Abstract: A spectrophotometer is provided, which comprises a receiving part diffusing an incident light, a first broadband filter group, and a detector detecting the light having passed through the first broadband filter group, in order to easily select and detect a plurality of lights having specific wavelengths, wherein the first broadband filter group comprises a first broadband filter arranged to have a first angle with respect to an incident direction of light to enable the incident light to pass through a first wavelength band, a second broadband filter arranged to have a second angle, which is different from the first angle, with respect to an incident direction of light to enable the light having passed through the first broadband filter to pass through a second wavelength band, and a first path compensation means for adjusting a path of the light having passed through the second broadband filter to be identical to a path of the light having passed through the first broadband filter, wherein the first broadband

Abstract: A spectrometry system may include an etalon array having a first etalon and a second etalon. The first etalon may be configured to process light to at least generate a first transmission pattern. The first transmission pattern may have at least a first transmission peak corresponding to a first wavelength in an original spectrum of the light. The second etalon may be configured to process the light to at least generate a second transmission pattern. The second transmission pattern may have at least a second transmission peak corresponding to a second wavelength in the original spectrum of the light. The first etalon may have a different thickness than the second etalon in order for the first transmission pattern to have at least one transmission peak that is at a different wavelength than the second transmission pattern. The first transmission pattern and the second transmission pattern may enable a reconstruction the original spectrum of the light.

Abstract: An interference fringe pattern generator forms an interference fringe pattern from the light rays diffused from a region of an object positioned against a background. A planar array of detector pixels is arranged to capture an image of the interference fringe pattern. A storage medium records information indicative of intensity values of the image of the interference fringe pattern captured by a selected group of pixels of the planar array of detector pixels. The information is recorded as a function of the optical path difference values traversed by the diffused light rays through the interference fringe pattern generator for each of the pixels in the selected group of pixels. A processor determines the spectral characteristics of the object based on the information indicative of the intensity values recorded by the storage medium and the optical path difference values traversed by the diffused light rays.

Abstract: A luminance evaluation image 1 has a determination portion 3 configured such that luminance changes progressively between low and high luminance regions 3a and 3b defined to have luminance levels lower and higher than an upper limit of luminance displayable on the image display device 4, respectively. A chromaticity evaluation image has a determination portion configured such that chroma changes progressively between low and high chroma regions defined to have chroma levels lower and higher than an upper limit of chroma displayable on the image display device 4, respectively. At least either the luminance evaluation image or chromaticity evaluation image is displayed on the image display device 4 to evaluate characteristics of the image display device 4 from a position of a boundary B1 in the determination portion 3.

Abstract: Disclosed is an illumination device for an apparatus for establishing the color of a tooth, including in the mouth, the illumination device including a support with a lens system that includes at least one lens, an illumination unit, image capturing unit, and a front protection. The illumination unit is arranged at the periphery of the visual field of the lens system.

Abstract: A short wave infrared polarimeter comprising a pixelated polarizer array and an Indium-Gallium-Arsenide (“InGaAs”) focal plane array.

Abstract: A temperature sensor configured to generate a temperature-indicating signal with improved accuracy over a wide temperature range is disclosed. The temperature sensor includes a first oscillator configured to generate a first oscillating signal with a first frequency that varies with a sensed temperature and a reference parameter; a second oscillator configured to generate a second oscillating signal with a second frequency that varies with the reference parameter; and a time-to-digital converter (TDC) configured to generate a digital output indicative of the sensed temperature based on a ratio of the first frequency to the second frequency. Because the first and second frequencies depend on the reference parameter, and the temperature-indicating signal is a function of the ratio of the first and second frequencies, temperature-variation in the reference parameter cancels out in the temperature-indicating signal.

Abstract: A fiber optic thermometer has a hollow body made of material of low thermal expansion and an optical fiber supported by a high thermal expansion intermediate support to form a cantilever section, a fiber optic splitter coupled to a first end of the optical fiber and a light source for directing light into the optical fiber via one branch of the optical splitter. A photodetector receives light conveyed through the optical fiber via the other branch of the optical splitter and measures intensity of the received light. A reflective target supported at a second end of the hollow body is axially aligned with the second end of the optical fiber at room temperature. Upon ambient temperature changes the cantilever section moves relative to the reflective target thereby changing the instantaneous intensity of light reflected by the target into the second end of the optical fiber and measured by the photodetector.

Abstract: This document describes techniques using, and devices embodying, radar-based force sensing. These techniques and devices can enable a great breadth of forces to be measured. Furthermore, radar-based force sensing enables those forces to use, control, and interact with devices.

Abstract: A sensor may include a bladder, and a deformable conductor disposed on the bladder such that deformation of the bladder causes deformation of the deformable conductor, wherein the bladder is constrained so as to enhance the deformation of the conductor in response to the deformation of the bladder. A method may include applying a stimulus to a bladder having a deformable conductor attached thereto, detecting a change in an electrical characteristic associated with the deformable conductor in response to the stimulus, and selectively constraining the bladder to amplify the change in electrical characteristic in response to the stimulus.

Abstract: A cable includes a longitudinal structural element including at least one of an electrical conductor and an optical conductor, and a strain sensor arranged within a bending neutral region of the cable and mechanically coupled with the longitudinal structural element. The strain sensor includes an optical fiber coated with at least one coating layer, a release layer surrounding the coating layer, and a protective layer surrounding the release layer. The release layer includes a material selected from a silicone polymer, a fluoropolymer mixture or an extruded polymer containing a slip agent.

Abstract: A novel six-dimensional force and torque sensor includes a central boss, a cylindrical housing arranged outside the central boss, and twelve elastic beams for connecting the central boss with the cylindrical housing. The twelve elastic beams are respectively provided with strain gauges as needed, and a bottom of the central boss is provided with a mounting hole for mounting a signal processing module. The present invention has the characteristics of self-decoupling, high rigidity, high natural frequency, desirable linearity, ideal repeatability and perfect hysteresis, and ability to measure a large torque (50 N·m). In addition, the sensor can be designed to have different measuring ranges and sensitivities by changing the dimensions of each of the elastic beams.

Abstract: Provided is a pressure detection device, wherein a pressure detection unit includes: a pressure detecting diaphragm; a second connection portion; and four strain resistance portions. One of either a first connection portion or the second connection portion is formed of a magnet, and the other of either the first connection portion or the second connection portion is formed of a magnet or a magnetic body. The first connection portion and the second connection portion are arranged such that the first connection portion and the second connection portion are attracted by a magnetic force in a state where a flow passage unit is mounted on the pressure detection unit. The four strain resistance portions are attached to a region of a second surface of a pressure detecting diaphragm other than a center portion.

Abstract: A sensor (2) is provided, having an acoustic resonator (18) for containing a fluid such as air and at least one transducer (22, 24) arranged to emit an acoustic signal into the acoustic resonator (18) in response to an excitation signal provided to the transducer (22, 24) by an electronic unit (4). The electronic unit (4) receives a response signal from at least one transducer (22, 24), and processes the excitation signal and the response signal to derive the acoustic signal response of the acoustic resonator. The pressure and/or temperature of the fluid may be derived from the acoustic signal response. More specifically, the electronic unit (4) may derive the temperature of fluid inside the acoustic resonator (18) by obtaining the resonant frequencies of the acoustic signal inside the acoustic resonator (18), or may derive the barometric pressure from the acoustic signal response in the vicinity of the fundamental frequency and its harmonics.

Abstract: A pressure detection device includes: a piezoelectric element that detects a pressure change via a diaphragm head or the like; a circuit board that is provided with a processing circuit that performs electrical processing with respect to a charge signal outputted from the piezoelectric element; a conductive housing member, which has conductivity and is disposed to cover (house) the circuit board, and which is connected to the ground of the circuit board; and a housing (a leading end side housing, the diaphragm head and a rear end side housing), which houses the piezoelectric element, the circuit board and the housing member, and which is electrically insulated from the piezoelectric element, the circuit board and the housing member.

Abstract: The invention relates to a wheel-force dynamometer (1) for the measurement by means of force sensors (6) of forces and torques that act upon a vehicle tire (2a) and a vehicle wheel (2), wherein the vehicle wheel (2) is mounted to rotate by means of a wheel axle. The wheel-force dynamometer (1) according to the invention is characterized in that the wheel axle is in the form of a rotor (3) which is hydrostatically mounted, axially fixed and able to rotate in the circumferential direction, in a rigid and positionally fixed housing (5).

Abstract: The electric cable (1) detecting presence of liquids includes at least two conductors (2, 2?) that are under dry conditions mutually electrically insulated with an insulation material and in presence of liquids they form a closed electric circuit. The insulation material is at least one paper shell (3) arranged in the form of a helix around at least one of the conductors (2, 2?).

Abstract: A leakage inspection method and leakage inspection device for container to be inspected are provided. When a container to be inspected having a deformable flexible part is to be inspected for leakage, the container to be inspected is filled with an inspection gas containing helium, the container to be inspected, which has been filled with the inspection gas, is disposed in an inspection chamber partitioned from the outside, and an upward flow of a carrier gas is formed from the lower part to the upper part of the container to be inspected. A leakage of the inspection gas filled in the container to be inspected is then detected on the basis of the result of measuring the concentration of helium in the carrier gas collected at a position higher than a position where the carrier gas is fed into the inspection chamber.

Abstract: Systems, devices, and methods for leak testing surgical conduit grafts or valved conduits such as aortic-valved conduits with a pressurized gas such as air. Air is non-destructive and especially useful for leak testing conduits that have coatings or sealants that may be functionally impacted when exposed to fluids such as water or saline. Open ends of the conduit are clamped and sealed, and a pressurized gas introduced into an inner lumen thereof. A change in mass flow rate is measured to quantify the leakage. One end of a tubular conduit may be clamped to a fixed manifold, and the opposite end to a manifold slidably mounted to accommodate any conduit elongation when pressurized. The clamping and sealing structure may be pneumatic and/or mechanical, and complementary contoured clamp members may be used to seal a scalloped external sealing ring of an aortic conduit.

Abstract: A leakage monitoring system for geomembranes comprises a power supply unit having two supply electrodes made from a nonmetallic conductive material and respectively connected to a membrane top and a membrane bottom of a primary geomembrane; a plurality of monitoring sensor electrodes made from the nonmetallic conductive material, uniformly arranged below the primary geomembrane and used for acquiring potentials at corresponding positions below the primary geomembrane; a data acquisition unit used for acquiring potential data of each monitoring sensing electrode; and a control and analysis unit used for analyzing the potential data of each monitoring sensor electrode acquired by the data acquisition unit, determining an abnormal potential area below the primary geomembrane to determine a leakage position of the primary geomembrane and giving an alarm. The abnormal potential area below the geomembrane can be determined to determine the specific leakage position of the geomembrane and give the alarm.

Abstract: An integrated controller for an environmental testing system simultaneously controls and synchronizes vibration, temperature, and humidity in an environment test chamber over a specified reliability test duration, and performs condition-based measurement and processing of vibration data obtained from the environment test chamber for one or more specified trigger conditions. The controller executes a combined run schedule using a single internal clock and a hardware processor, to generate parameter control commands for the environment test chamber that remain synchronized to the single internal clock over the duration of a test, even one that lasts for weeks or months. This permits multi-variate processing of measured instantaneous values of temperature, humidity, and vibration to obtain, e.g., condition-dependent vibration power spectra and averages for available conditions of temperature, humidity, or both.

Abstract: A system for calibrating a test vibration transducer having at least one vibration measurement channel, including a vibration generator, a reference vibration transducer, a fastening device for rigidly coupling the reference vibration transducer to the test vibration transducer, in order to set the reference vibration transducer and the test vibration transducer into vibrations jointly. The vibration generator, and an analysis unit, wherein the reference vibration transducer is designed to output a corresponding reference measurement channel for each vibration measurement channel of the test vibration transducer and also at least one additional reference measurement channel for an additional degree of freedom to the analysis unit. The analysis unit has an input for each vibration measurement channel of the test vibration transducer and is designed to offset the vibration measurement signals of the test vibration transducer with the reference signals.

Abstract: The present invention relates to an optical time domain reflectometer using, as a optical source, a polymer wavelength tunable laser which tunes the wavelength of an optical signal by using polymer grating. The optical time domain reflectometer of the present invention tunes the wavelength of a polymer wavelength tunable laser that outputs a constant optical signal and inspects cutting, reflection, and damage of an optical line by separating an optical signal returning from the optical line by an optical filter having a specific central wavelength. Since a optical source having a constant light intensity is used, the present invention has an effect of reducing the nonlinear effect generated in an optical line.

Abstract: A method for estimating life of a piston ring includes obtaining a reference profile of the piston ring. The reference profile comprises a plurality of reference fiducials. The method further includes receiving a measured profile of the piston ring. The measured profile comprises a plurality of measured fiducials. The method further includes aligning the measured profile with the reference profile based on one or more of the plurality of reference fiducials and one or more of the plurality of measured fiducials. The method also includes determining one or more wear parameters based on the aligned measured profile and the reference profile. The method also includes generating a wear model based on the one or more wear parameters. The method also includes estimating a life of the piston ring based on the wear model.

Abstract: A device includes a main body and at least one actuating and sensing module. A length of the main body is 5˜40 mm. A width of the main body is 5˜27 mm. A height of the main body is 2˜10 mm. The actuating and sensing module is disposed in the main body. The actuating and sensing module includes a carrier, at least one sensor, at least one actuating device, a driving and transmitting controller and a battery. The sensor, the actuating device, the driving and transmitting controller and the battery are disposed on the carrier. The actuating device is disposed on one side of the sensor. The actuating device includes at least one guiding channel. The actuating device is enabled to transport fluid to flow toward the sensor through the guiding channel so as to make the fluid measured by the sensor.

Abstract: A method of determining particulate content in a hydraulic fluid contained in a hydraulic circuit the circuit having a standard hydraulic sampling output for sample collection comprising the steps of: connecting the sampling output to an adapter having a body unit with an internal press risible volume, an input and an output to the volume, and valve means whereby the input and output are either linked to one another or isolated from one another; the connection to the sampling output being by way of the adapter inlet; connecting the output of the adapter to a particle counter to provide an operable sampling combination; operating the valve means to provide for the input and the output of the adapter to be coupled to allow the controlled flow of pressurised hydraulic fluid from the sampling output to the counter so as to provide a sample of the fluid for analysis by the counter.

Abstract: Provided is a method for selectively separating samples from a substrate. The method includes: providing a substrate mounted with samples; selecting one or more desired target areas from areas of a layer of the samples; patterning an energy source so as to correspond to the target areas; and extracting energy from the patterned energy source, applying the extracted energy to the target areas such that target samples corresponding to the target areas are released from the substrate, and recovering the target samples.

Abstract: A real-time imaging method and system for monitoring an assay process performed on a biological sample is described. In some embodiments, the method and system can be used to measure and control a reagent volume confined to a space between a cover and a substrate, which is particularly useful for controlling for evaporation in a thin-film staining environment. In particular embodiments, the disclosed reagent volume sensing and replenishment method and system are resistant to system noises generated during operation, for example, system noise due to vibration, field of view blockage by dispenser systems, differences in reagent colors, and changing tissue colors.

Abstract: The present disclosure relates to a blood staining patch, a method and device for a blood test using the same, and more particularly, to a patch configured to contain a staining reagent for staining blood and a method and device for economically testing blood using the same. A blood testing method according to an aspect of the present disclosure, which is a blood testing method in which a patch, which includes a mesh structure forming micro-cavities and is configured to contain a staining reagent for staining staining targets present in blood in the micro-cavities, is used to perform a blood test through staining of the staining target, includes placing blood in a reaction region, and providing the staining reagent to the reaction region using the patch configured to contain the staining reagent.

Abstract: A method including: providing a sample with M components to be labeled, where M>2; labeling the components with N stains, where N<M so that at least two components are labeled with a common stain; obtaining a set of spectral images of the sample; classifying different parts of the sample into respective classes that distinguish the commonly stained components based on the set of spectral images; and determining relative amounts of multiple ones of the M components in different regions of the sample. Related apparatus are also disclosed.

Abstract: The present disclosure relates to a diagnostic method and a device performing the same. According to an aspect of the present disclosure, a diagnostic device is a diagnostic device that uses a test kit including a specimen plate having a specimen region in which a specimen is smeared and a patch plate configured to store a contact-type patch, which comes into contact with the specimen to stain the specimen, and the diagnostic device includes a body having a loading region in which the test kit is placed, a moving unit configured to move the patch plate and the specimen plate of the test kit relative to each other so that the specimen placed in the test kit is smeared in the specimen region, and a contact unit configured to move a structure of the test kit such that the contact-type patch comes into contact with the smeared specimen so that the smeared specimen is stained.

Abstract: An enzymatic sample purifier comprises a reaction chamber containing an enzyme, a product chamber and a separator. The reaction chamber has a port to receive a sample comprising a protein degradation product. The separator retains polypeptides resulting from reaction of the protein degradation product with the enzyme in the reaction chamber and facilitates transport of purified remaining portions of the sample comprising a target analyte to the product chamber.

Abstract: A particle electrical mobility classifier is provided for the classification of particles (e.g., particles less than 1 ??? in size) based on their electrical mobility. The particle classification zone is curved. In an exemplary embodiment, two metal concentric cylinders, separated by an annular insulation spacer, establish a particle classification zone. A DC electrical field is supplied by the cylinders in the circular classification zone. An example classifier can be operated in different modes such as: (1) as a particle precipitator; (2) as a particle electrical mobility separator, and (3) as a differential mobility classifier. The curved classification zone results in a particle classifier having an extended particle sizing range as compared to their counterparts in classical configurations. The curve of the classification channel (in the flow direction) may be in any of several configurations (e.g., circular, wavy, spiral, or helical).

Abstract: A system and method for accurately and efficiently testing a HEPA filter in a sterile environment, such as a clean room, by creating a closed-loop system. The system includes a multi-port interface including at least a challenge port and a verification port, each port being in communication with an area upstream from the HEPA filter. Through the challenge port, test substances are introduced to a supply air duct that is in communication with a HEPA filter. Through the verification port, a concentration of the test substances can be measured for comparison with a concentration that passed through the HEPA filter, i.e. downstream from the HEPA filter. As such, test substances can be dispersed throughout the air conditioning system before interacting with the HEPA filter, and accurately measured. The closed loop between the ports provides an accurate measurement of the concentration of test substances to test the HEPA filter.

Abstract: An acoustic separation device for reagent manipulation a standing acoustic including a wave generating device and pairs of perforated pseudo walls comprising a longitudinal standing bulk acoustic wave (LSBAW) channel. The LSBAW channel provides local pressure field amplification to overcome drag forces arising from reagent flow. Further, method for manipulating a reagent under continuous flow conditions microcarrier particles locally confined in an acoustic separation device comprising an inlet and an outlet, a fluid routing layer coupled to a channel, a plurality of loading wells configured to hold a plurality of substances required for a desired synthesis, and a controller configured to distribute the plurality of substances held by the loading wells in a desired sequence. The device for antibody manipulation further comprises an ultrasound actuator, and a channel wherein the channel is separated from the ultrasound actuator.

Abstract: A system and method include a resonator device including walls forming a channel, where the walls are shaped to simultaneously confine light in an optical mode and to confine vibration in a mechanical mode, and where the mechanical mode is selected so that vibration in the mechanical mode can couple to the optical mode. A waveguide is coupled with the resonator device for guiding a probe light through the resonator device. An electro-mechanical actuation mechanism provides a mechanical drive force to the resonator device. A photodetector measure light outputted by the waveguide after passing through the resonator device, the outputted light including a modulated version of the probe light based on passing through the resonator device and interacting with a fluid, or a fluid containing a particle, contained by the channel of the resonator device.

Abstract: This present invention relates generally to devices, systems, and methods for performing bioimaging at the microscopic scale and, more particularly, to devices and systems including a disposable testing device configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device. In some aspects, a method is provided for performing a differential blood cell count. The method including moving a blood sample into a sample testing conduit having a first wall formed from at least a portion of an imager chip, a second wall formed from a transparent material layer, and a plurality of spacer elements. The method further including driving a light emitter to project light through the chamber, recording an output signal of at least one of absorbance and fluorescence, and converting the output signal to a number count or percentage for each type of cell in the blood sample.

Abstract: A system for measuring corrosion and corrosion-erosion rates in a high temperature, high pressure multiphase dynamic environment includes a plurality of ring-shaped test coupons disposed within a test vessel in a vertical arrangement relative to one another. A test fluid mixture is added to the vessel and the temperature and pressure are maintained such that the mixture exists in a multiphase condition that has a vertical stratification such that each test coupon is exposed to a different phase and/or combination of phases of the fluid. Impellers can be used to stir the fluid to provide a dynamic environment. The fluid can include particulate matter to simulate real world test conditions. Separator plates can be disposed at different vertical locations within the vessel to maintain separation between various phases of the fluids and further restrict particulate matter from migrating between sections of the test system.

Abstract: A system for testing adhesive is disclosed, comprising a pull testing machine and a rigid spine. The rigid spine has a face extending along a longitudinal axis between a first and second projection, and one of the projections is moveable relative to the other. The face is configured to support a substrate, with a flexible media adhered to the substrate. The rigid spine also has a coupler configured to connect the spine to the pull testing machine.

Abstract: A bond test apparatus comprises a test tool assembly 200 comprising a test tool 40 configured to contact a bond during a bond test, a flexure 80 coupled to the test tool assembly, and a sensor. The sensor is configured to provide a measurement of a displacement of a first end of the flexure 80 relative to a second end of the flexure on application of a force to the flexure, and a processor is configured to receive a displacement signal from the sensor and, based on the displacement signal and optionally a known stiffness of the flexure, to determine the force on the flexure. A cartridge for a bond test apparatus, a method of measuring a force in a bond test apparatus, and a method of measuring the closing force on the jaws of a bond test tool are also provided.

Abstract: Provided are a diagnostic device and the like for easily diagnosing the condition of the interior of a pipeline. This diagnostic device is provided with: a frictional loss calculating unit which, on the basis of the pressure of a fluid in the pipeline, finds a pressure frictional loss; and a diagnosing unit which diagnoses the condition of the inner surface of the pipeline on the basis of the frictional loss.

Abstract: An optical sensing device includes a substrate; a first dielectric layer extending thereon; a plurality of pairs of opposite antennas patterned on the first layer; and a second dielectric layer that covers all of the antennas. Opposite antennas are, in each of the pairs, separated by a gap g, which, on average, is between 1 nm and 50 nm, as measured in a direction x parallel to a main plane of the substrate. The pairs of antennas have different geometries. The second layer covers all the antennas and defines an electro-magnetic field enhancement volume between the opposite antennas of each of the pairs, thanks to the gap. Electro-magnetic radiation can be concentrated in each volume, making it possible to optically sense an analyte via opposite antennas of each of the pairs. Such a device allows analytes to be funneled and guided into the field-enhanced volumes for deterministic sensing.

Abstract: Systems and methods of the present disclosure are directed to detecting species within a fluid using a multi-pass absorption cell and a spectrometer. The absorption cell includes a plurality of mirrors arranged in a manner such that a detection light traverses multiple passes through the fluid within the absorption cell. In some implementations, the detection light is reflected by the plurality of mirrors to form optical paths in more than one plane. The system also includes an electronic unit configured to receive and process spectral data from the spectrometer. In some implementations, the electronic unit communicates with at least one computational unit over a communication interface to send a portion of the spectral data for processing. The electronic unit may also receive processed data from the computational unit.

Abstract: Systems and methods of the present disclosure are directed to detecting species within a fluid using a multi-pass absorption cell and a spectrometer. The absorption cell includes a plurality of mirrors arranged in a manner such that a detection light traverses multiple passes through the fluid within the absorption cell. In some implementations, the detection light is reflected by the plurality of mirrors to form optical paths in more than one plane. The system also includes an electronic unit configured to receive and process spectral data from the spectrometer. In some implementations, the electronic unit communicates with at least one computational unit over a communication interface to send a portion of the spectral data for processing. The electronic unit may also receive processed data from the computational unit.

Abstract: A flow cell assembly (16) for a fluid analyzer (14) that analyzes a sample (12) includes (i) a base (350) that includes a base window (350B); (ii) a cap (352) having a cap window (352B) that is spaced apart from the base window (350B); and (iii) a gasket (360) that is secured to and positioned between the base (350) and the cap (352), the gasket (360) having a gasket body (360A) that includes a gasket opening (360B). The gasket body (360A), the base (350) and the cap (352) cooperate to define a flow cell chamber (362). Moreover, an inlet passageway (366) extends into the flow cell chamber (362) to direct the sample (12) into the flow cell chamber (362); and an outlet passageway (368) extends into the flow cell chamber (362) to allow the sample (12) to exit the flow cell chamber (362).

Abstract: Pump-probe spectroscopy systems are provided. In an embodiment, such a system comprises an optical subsystem configured to generate a pulsed pump beam and a pulsed probe beam, the pulsed probe beam having a probe pulse frequency ? of at least 20 kHz; a detector subsystem configured to detect a sample signal induced by the pulsed pump beam and the pulsed probe beam; a chopper configured to adjust the frequency of the pump beam to ?/2, wherein the chopper is synchronized with a detector of the detector subsystem but is unsynchronized with the pulsed probe beam; and a data acquisition subsystem configured to initiate acquisition of image data by the detector based on a trigger signal derived from the pulsed pump beam.

Abstract: A non-destructive method of estimating hematocrit (Hct) of whole blood from a dried blood sample prepared from the whole blood, the method comprising: a) determining the amount of hemoglobin derivatives comprising oxyhemoglobin, methemoglobin and hemichrome (total hemoglobin) in a dried blood sample, wherein the sum of the amounts of the hemoglobin derivatives remains constant in the dried blood sample in function of time, and b) estimating the hematocrit from the sum of the amounts of the hemoglobin derivatives, wherein the hematocrit is estimated using a calibration curve providing a correlation between hematocrit and the amount of the hemoglobin derivatives in a dried blood sample. The amount of the hemoglobin derivatives is preferably determined by measuring the reflectance, absorbance, or transmittance of the dried blood sample at the quasi-isosbestic point of the hemoglobin derivatives about 589 nm or at multiple wavelengths within the range of 450 to 750 nm.

Abstract: A compact spectrometer system comprising a light source and a spectrometer module and methods of using a spectrometer to determine information related to a property of a mixture are provided. One or more light sources are used to direct light into a mixture. One or more spectrometer modules are used to receive light from a mixture. One or more spectra are measured in response to the received light. A property of the mixture is determined in response to measured spectra.