Abstract: The present invention provides an antibody for detecting mesothelioma and an antibody having high specificity to mesothelioma and high sensitivity thereto. The present invention also provides a method of diagnosis of mesothelioma by using the antibody, a reagent containing the antibody for use in diagnosis of mesothelioma, and a kit comprising the antibody for use in diagnosis of mesothelioma. Further, the present invention provides a marker for use in diagnosis of mesothelioma. Furthermore, the present invention provides a pharmaceutical composition containing the antibody according to the present invention or an antigen-binding fragment thereof for use in treatment of mesothelioma. An antibody that binds to a glycosylated HEG1 protein obtained from mesothelioma.

Abstract: The present disclosure relates to the treatment of cancers and, more particularly, to the treatment of ADAM17 substrate dependant cancers which are refractory. The pharmaceutical composition contains an ADAM17 antibody (it recognizes an epitope within the membrane proximal domain of ADAM17 localized between the residues 564 and 642) characterized by the sequences of its variable chains.

Abstract: A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided.

Abstract: This method for aiding Alzheimer's detection provided by the present invention includes: determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. A difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing Alzheimer's.

Abstract: The invention relates to fine and uniform copolymer powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having a defined particle size distribution. In particular; it relates to powders that are suitably used in the areas of oral care and pharmaceuticals and to methods for preparing the powders. Provided is a composition of powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having: (i) a Dv50 of less than or equal to 25 microns; a Dv90 of less than or equal to 50 microns; and (ii) a particle uniformity reflected by a Dv90/Dv10 ratio of less than or equal to 10.

Abstract: A curable composition capable of manufacturing a cured product having a high refractive index is provided. The curable composition contains a polymerizable compound represented by formula (1) and inorganic particles. In formula (1), La represents a divalent linking group, and the divalent linking group includes at least one of a divalent aromatic group, a divalent polycyclic aliphatic group and an alkylene group having an aromatic group, Ar represents an aromatic group, and R represents an aromatic group optionally having one or more substituents or a polycyclic aliphatic group optionally having one or more substituents.

Abstract: The present invention relates to a superabsorbent polymer having excellent short time free absorbency. The superabsorbent polymer may exhibit excellent centrifuge retention capacity and absorbency under load, as well as excellent short time free absorbency. Thus, it can fundamentally solve the problems of the existing superabsorbent polymer and technical requirement of the art, and can provide various hygienic goods exhibiting more excellent properties.

Abstract: The present invention relates to a modifier represented by Formula 1, a method of preparing the same, a modified conjugated diene-based polymer having a high modification ratio which includes a modifier-derived functional group, and a method of preparing the polymer.

Abstract: A conductive polymer formed by the photochemical condensation polymerization of polyacetylene. E,E,1,4-diiodobuta-1,4-diene ICH=CH?CH+CHI (DIBD) in a crystalline urea inclusion compound is illuminated with low power broad spectrum pulsed UV visible radiation to form an irradiated DIBD urea inclusion compound that exhibits superconductivity and can be configured into an energy storage device that is rechargeable via magnetic induction. Altnernatively, (E,E,E)-1,6-diiodohexa-1,3-5-triene may be used as the guest monomer that is polymerized in the crystalline urea inclusion compound and the resulting polyacetylene urea composite crystal may be formed into a circuit for use as a superconductor.

Abstract: A polymer composition adapted for use in injection stretch blow molding may include a metallocene random propylene-based copolymer in the absence of a clarifier. The metallocene random propylene-based copolymer may exhibit a melting point of from 105° C. to less than 175° C., a recrystallization temperature ranging from 85° C. to 100° C. as measured by DSC, a microtacticity ranging from 89% to 99%, a molecular weight (Mw) ranging from 170,000 to 210,000, and a melt flow rate of from about 1 dg/min. to about 40 dg/min. A method of forming an injection stretch blow molded (ISBM) article may include providing the metallocene random propylene-based copolymer, injection molding the metallocene random propylene-based copolymer in the absence of a clarifier into a preform, and stretch-blowing the preform into an article.

Abstract: Process for producing an aqueous binder comprising at least one polycarboxylic acid, at least one compound having at least two hydroxyl groups, and at least one phosphorus compound.

Abstract: A process for preparing moisture curable compounds and moisture curable compositions prepared from the product of that process is provided.

Abstract: The invention relates to polymers derived at least from one: (A) one N-vinyl amide unit, and (B) one hydroxyl-containing acrylate unit, and to polymers derived at least from: (A) N-vinyl-2-caprolactam, and (B) one non-acrylate unit having: (i) at least one hydroxyl group, and/or (ii) at least one functional group convertible to a hydroxyl group wherein at least one group is converted to hydroxyl functionality in the final polymer product. Such polymers may exhibit degradability, e.g., in seawater or soil environments. In preferred embodiments, these polymers and compositions thereof are used in oilfield applications, such as an inhibitor of gas hydrates and/or a kinetic inhibitor of gas hydrates. The polymer can assume alternating, block, and/or random configurations of the repeating units, with at least one ester group. The chemical structure subscripts m, and n may be any integer equal to or greater than 1.

Abstract: A copolymer latex of a copolymer comprising 50 to 88 wt % of a conjugated diene monomer unit, 10 to 40 wt % of an ethylenically unsaturated nitrile monomer unit, and 2 to 10 wt % of an ethylenically unsaturated acid monomer unit, the copolymer latex having an insoluble content in methyl ethyl ketone of 70 wt % or less and a swelling degree in methyl ethyl ketone of 40 times or more when the copolymer is formed into a dry film.

Abstract: A composition for an encapsulant according to an embodiment of the present application comprises: 1) a silicone resin; 2) one or more moisture absorbents; 3) one or more photoinitiators; and 4) a monomer capable of dissolving the photoinitiators.

Abstract: Thermoplastic polymer compositions having enhanced properties, as well as methods of making and using the same, are provided. Thermoplastic polymers according to some aspects of the present invention may be rigid, but may also be suitable for use in applications requiring a thermoplastic polymer resin. Thermoplastic polymers according to various aspects of the present invention may be useful in preparing shaped articles such as, for example, sheets, films, tubes, preforms, bottles, profiles, and other similar articles.

Abstract: An aromatic polyester polyol having a nominal functionality of at least about 2 is produced from the esterification reaction of a phthalate-based composition containing less than 50 mol % of ortho-phthalic acid or phthalic anhydride, with a hydroxyl material containing at least 20 mol % of at least one branched aliphatic diol, and optionally transesterified with at least one hydrophobic material. The polyester polyol has improved shelf-life stability as demonstrated by the polyester polyol remaining clear and homogeneous for at least 6 months when stored at room temperature. The polyester polyol, when incorporated into a polyol foam-forming resin composition in an amount of at least 40 wt %, results in polyurethane and polyisocyanurate foams that exhibit low smoke and weight loss upon burning conditions.

Abstract: A fiber formed from a resin including a silicone-modified polyurethane resin comprising the reaction products of a polyol (A), a chain extender (B), an active-hydrogen-group-containing organopolysiloxane (C), and a polyisocyanate (D), wherein the active-hydrogen-group-containing organopolysiloxane (C) contains an active-hydrogen-group-containing organopolysiloxane (C-1) having a carbinol group at only one terminal.

Abstract: A crosslinked polyurethane obtainable by a process is disclosed wherein polyisocyanates are mixed with polymeric compounds having at least two hydrogen atoms reactive toward isocyanate groups and comprising at least one diene block copolymer which has at least two hydrogen atoms reactive toward isocyanate and has a polydiene main chain and at least one side chain or terminal chain composed of a polyether and/or a polyester, where the proportion by weight of the polydiene main chain is, based on the total weight of the diene block copolymer, from 25 to 95% by weight, to give a reaction mixture that is cured. Composites and blends composed of crosslinked polyurethane and rubber are also disclosed, as well as the use of crosslinked polyurethane in the production of tires or parts of tires, cable sheathing, shoe sole, roller or hose.

Abstract: A process for the preparation of insulation systems for electrical engineering by automatic pressure gelation (APG) or vacuum casting, wherein a multiple component thermosetting resin composition is used, said resin composition comprising (A) at least one epoxy resin, (B) at least one carboxylic acid anhydride curing agent, and (C) 2,4,6-tris(dimethylaminomethyl)phenol, provides encased articles exhibiting good mechanical, electrical and dielectrical properties, which can be used as, for example, insulators, bushings, switchgears and instrument transformers.

Abstract: A composition with improved adhesive and sealant properties comprises a) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1; wherein the content of grafted anhydride in the composition is less than 0.05 mol/mol of polyacid.

Abstract: Provided herein are methods and systems for producing biodegradable beta-propiolactone-based polyester polymers from renewable EO and CO on an industrial scale.

Abstract: Provided is a polyorganosiloxane, wherein a value obtained by integrating dw/d log(M) from 2.5?log(M)?3.

Abstract: The present invention relates to composition comprising an aqueous dispersion of microspheres and a class of a nonionic polyalkylene oxide of a distyryl or tristyryl phenol or an anionic polyalkylene oxide salt of a distyryl or tristyryl phenol and a process for preparing the composition. The microspheres have an average particle size in the range of from 1 ?m to 25 ?m, as well as a low coefficient of variation and low gel concentration; the composition is useful in coatings applications, especially where a matte finish is desired.

Abstract: A terminally modified imide oligomer is represented by a specific formula including a 2-phenyl-4,4?-diaminodiphenylether residue or a 4-phenoxy-1,3-diaminobenzene residue. A varnish is obtained by dissolving the terminally modified imide oligomer. A cured product is obtained by heat-curing the terminally modified imide oligomer, and a film including the cured product has a tensile elongation at break of 10% or more. An imide prepreg is obtained by impregnating fibers with the varnish and then drying the impregnated fibers. A fiber-reinforced composite material is obtained by layering and then heat-curing the imide prepreg.

Abstract: A thermoplastic aromatic polysulfone is obtained by polymerizing a dihalogeno compound (A) and a dihydric phenol (B). The ratio (Mw/Mn) between a number average molecular weight (Mn) and a weight average molecular weight (Mw) is at least 1.91, and the number average molecular weight (Mn) is at least 6,000 and less than 14,000, In (A) and (B), each of X and X? independently represents a halogen atom; each of R1, R2, R3 and R4 independently represents an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms; each of n1, n2, n3 and n4 independently represents an integer of 0 to 4; and when n1, n2, n3 or n4 is an integer of 2 to 4, a plurality of R1, R2, R3 or R4 groups may be the same or different from each other.

Abstract: The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.

Abstract: The invention relates to a method to reduce or prevent agglomeration of polyisobutylene particles in aqueous media by LCST compounds and highly pure polyisobutylenes obtained thereby. The invention furthier relates to polyisobutylene products comprising the same or derived therefrom.

Abstract: The invention relates to a process for modifying polymer particles of an aqueous polymer dispersion in which positively or negatively charged polymer particles are provided with an inorganic salt shell. The inorganic shell leads to an improved drying ability and storage stability of the latex and improves the storage stability of the resulting polymer powder. The obtained polymer powder exhibits an improved viscosity and faster skin-forming time in the final application and is therefore particularly useful in a building material composition.

Abstract: The invention provides for a method manufacturing artificial turf infill (602), wherein the method comprises providing (700) an initial composition (1120) comprising a granulate (1006), at least one type of pigment, and a fluid binding agent. The fluid binding agent comprises at least one type of polymer component. The method further comprises mixing (702) the initial composition; adding (704) water and a catalyst to the initial composition during the mixing of the initial composition to cure the fluid binding agent and the at least one type of pigment into an initial coating (200) of the granulate. The method further comprises providing (706) a subsequent composition (1122) comprising the granulate with the initial coating, the at least one type of pigment, and the fluid binding agent. The method further comprises mixing (708) the subsequent composition.

Abstract: A color-changing polymeric material is provided. The material is formed from a thermoplastic composition containing a continuous phase that includes a matrix polymer, colorant, microinclusion additive, and nanoinclusion additive, wherein the microinclusion additive and nanoinclusion additive are dispersed within the continuous phase in the form of discrete domains. A porous network is formed in the polymeric material when subjected to a deformational strain in a solid state. The polymeric material exhibits a first color prior to being subjected to the deformational strain and a second color after being subjected to the deformational strain, the first color being different than the second color.

Abstract: A resin composition is provided. The resin composition comprises the following components: (A) epoxy resin; (B) a cross-linking agent; (C) bismaleimide resin (BMI) represented by the following formula (I): wherein R1 is an organic group; and (D) a resin represented by the following formula (II): wherein n is an integer of 1 to 10.

Abstract: A fiber-reinforced polyamide resin base material comprises continuous reinforcing fibers, or comprises a reinforcing fiber base material in which discontinuous reinforcing fibers are dispersed, impregnated with a polyamide resin. In the polyamide resin, at least part of the polymer constituting the polyamide resin is an end-modified polyamide resin having, at an end group of the polymer, a structure constituted by a structural unit different from a repeating structural unit constituting the backbone of the polymer. A fiber-reinforced polyamide resin base material having an excellent impregnation property and thermal stability, less void, and excellent surface quality is provided.

Abstract: A foaming process for converting fibrous material into a cellular foam structure includes mixing fibrous material and a solvent-based binding agent to form a mixture; saturating the mixture with a pressurized gas to form a gas-saturated mixture; expanding the gas-saturated mixture by reducing the pressure of the pressurized gas to form an expanded mixture with voids in the fibrous material; and curing the expanded mixture to set the fibrous material and drive off the solvent to provide a stable network of fibrous material having cushioning properties.

Abstract: Methods of treating carbon nanotubes include disposing a plurality of carbon nanotubes in a chamber; reducing a pressure of an atmosphere within the chamber; increasing a temperature within the chamber; and removing gases from interstices within at least some of the plurality of carbon nanotubes. A composition of matter includes a plurality of carbon nanotubes defining interstices therein; an inert gas disposed within at least some of the interstices in the carbon nanotubes; and a matrix material mixed with the plurality of carbon nanotubes.

Abstract: A polymer hybrid material, a film comprising the polymer hybrid material, the use of the polymer hybrid material, a splitting method using the polymer hybrid material, and a method for producing the polymer hybrid material are provided for increasing the total yield, i.e. the efficiency with respect to the raw materials used and other resources such as energy and workforce, of a splitting method. The polymer hybrid material for use in a splitting method has at least two solid-body sections produced from a solid-body starting material. The polymer hybrid material comprises a polymer matrix and a first filler and a second filler embedded into the polymer matrix.

Abstract: Provided are an adhesive film, and an organic electronic device (OED) encapsulation product using the same. Dimensional stability, lifespan, and durability may be enhanced even when a panel of an organic electronic device is large-sized and formed as a thin film by controlling dimensional tolerance and edge angular tolerance of the adhesive film, thereby ensuring long-term reliability, and process yields may be enhanced when the adhesive film is applied to an automation process.

Abstract: A fan containing a polyester resin composition containing a thermoplastic polyester resin (A) constituted of a dicarboxylic acid component and a diol component, including, for example, polybutylene terephthalate resin, polytrimethylene terephthalate resin, polyethylene terephthalate resin, and the like, one or more members selected from the group consisting of plasticizers and elastomers (B), and an inorganic filler (C). Since the fan of the present invention has a short vibration time even while having a high flexural modulus as a structural member, in the manufactured product equipment or apparatus or structured article that generates vibrations or noises, even when a fan is placed in the surroundings of the sources of vibrations or noises, the generated vibrations are damped and consequently excellent effects are exhibited that extraneous vibrations pertaining to properties of manufactured products or apparatus or unpleasant vibrations or vibrating sounds or noises are reduced.

Abstract: A crystalline pigment or colorant composition having high color intensity and/or low sugar content, and methods and processes of preparation. The composition may comprise purified fruit and/or vegetable color juices.

Abstract: The present invention relates to phosphoric ester preparations with reduced hygroscopicity, to use of these as flame retardants and hydraulic fluids, and to polyurethanes which comprise the phosphoric ester preparations of the invention.

Abstract: A flame-retardant microcapsule with a shell containing a cyclic phosphazene molecule, a process for forming a flame-retardant microcapsule with a shell containing a cyclic phosphazene molecule, and an article of manufacture including a flame-retardant microcapsule with a shell containing a cyclic phosphazene molecule are disclosed. The process for forming the flame-retardant microcapsule with the shell containing the cyclic phosphazene molecule may include providing a cyclic phosphazene molecule, forming an aqueous mixture containing the cyclic phosphazene molecule, adding a payload agent into the aqueous mixture, and adding a curing agent into the aqueous mixture.

Abstract: Provided herein, inter alia, are a carbon fiber-reinforced polymer composite and a method for manufacturing the same. The carbon fiber-reinforced polymer composite may improve interfacial bonding force by modifying the surface of carbon fibers with an amphiphilic block copolymer and then forming a composite of the surface-modified carbon fibers with a polymer.

Abstract: The present invention relates to processes for making compatibilized high aspect ratio barrier additives and polymer compositions that comprise compatibilized high aspect ratio barrier additives. The invention also relates to compositions produced by these processes, and articles formed from polymer compositions of this invention. The barrier additives provide passive barriers to gas molecules such as oxygen and carbon dioxide minimizing transit of such molecules through sidewalls of polymer articles containing the barrier additives.

Abstract: Provided is a rubber composition which contains a diene rubber and a reinforcing filler, and the diene rubber contains a styrene-butadiene copolymer component including at least one type of styrene-butadiene copolymer and satisfying the following requirements: (1) the bonded styrene content is from 5 to 50 wt. %; (2) among components obtained by ozone decomposition, a content of a decomposed component V1 containing one 1,2-bonded butadiene-derived unit out of a total of 100 mol % of decomposed components containing styrene-derived units and/or 1,2-bonded butadiene-derived units is not less than 25 mol %; (3) among components obtained by ozone decomposition, a content of a decomposed component S2V1 containing two styrene-derived units and one 1,2-bonded butadiene-derived unit out of a total of 100 mol % of decomposed components containing styrene-derived units and/or 1,2-bonded butadiene-derived units is less than 5 mol %; and (4) a vinyl content of a butadiene moiety is not less than 50%.

Abstract: The invention relates a pipe for the transport of water with improved resistance to chlorinated disinfectants. The pipe is produced with a polymer composition comprising polyethylene and zinc sulfide.

Abstract: A polymer composition is provided. The polymer composition includes a polyolefin, at least 30% by weight of a thermoplastic elastomer, and a filler material. When the polymer composition is formed into an article having a longitudinal axis, the polymer composition has an average coefficient of thermal expansion along a longitudinal axis of less than or equal to 150×10?6 m/mK as measured from ?40° C. to 25° C. Further, the polymer composition has an elastic modulus of less than 3000 MPa as measured using dynamic mechanical analysis (ASTM D4065), and the polymer composition has an elongation at break of greater than 200% along the longitudinal axis (measured according to ASTM D638). An article made from the polymer composition and a cable including the polymer composition are also provided.

Abstract: The present invention relates to a polymer composition with flame retardant activity, to a use of the polymer composition for producing an article, to an article comprising the polymer composition, preferably to an article which comprises a layer element comprising at least one layer which comprises the polymer composition.

Abstract: The invention pertains to a (per)fluoroelastomer composition comprising at least one (per)fluoroelastomer [(per)fluoroelastomer (A)] matrix comprising particles of at least one perfluoropolymer [polymer (F)] having a melt flow index (MFI), measured at 372° C. under a 5 Kg load according to ASTM D1238 standard, of less than 10 g/10 min, said particles having an average size of less than 100 nm.

Abstract: Provided is an optical component comprising a methacrylic resin composition having excellent surface processability and displaying excellent preservability of formed surface processing. The optical component contain a methacrylic resin including a structural unit (X) having a cyclic structure-containing main chain that is at least one selected from the group consisting of an N-substituted maleimide monomer-derived structural unit, a glutarimide-based structural unit, and a lactone ring structural unit. The methacrylic resin composition has a Vicat softening temperature of 120° C. to 160° C. Among methacrylic acid ester monomer-derived structural units, a ratio (S/H) of the integrated intensity (S) of a syndiotactic fraction (rr) relative to the integrated intensity (H) of a heterotactic fraction (mr), as determined by 1H-NMR measurement, is 1.20 to 1.50. The amount of methanol-soluble content is 5 mass % or less relative to 100 mass %, in total, of methanol-soluble content and methanol-insoluble content.

Abstract: The present disclosure relates to a phosphorus compound represented by the following Chemical Formula 1. In the above Chemical Formula 1, Ar is aryl and R1, R2, R3, R4, R5, and R6 are each independently H, substitutable linear or branched C1-C20 alkyl and substitutable C6-C20 aryl, the aryl includes a member selected from the group consisting of phenyl, biphenyl, naphthalene, fluorene, anthracene, phenanthrene, pyrene, fluoranthen, chrysene, benzofluoranthen, perylene, quinoline, indenoanthracene, indenophenanthrene, hydroanthracene, dibenzothiophen, dibenzofuran, and combinations thereof, and the substitution is substitution with C1-C6 alkyl or C6-C20 aryl, but may not be limited thereto.