Abstract: A pressurizable fluid supply apparatus may include a bag to hold a fluid. The bag may include a fluid outflow interface and a bladder positioned adjacent to the bag. The bladder may include a plurality of chambers positioned vertically in series. Adjacent chambers may be separated by dividers. The dividers may be configured to allow fluid flow between adjacent chambers under specified conditions. The bladder may further include a pressure inlet positioned at a top of the bladder.

Abstract: A system and method that identifies delayed infusion programs at an infusion pump or with a first computer and an infusion pump. The first computer receives an infusion auto-program from a remote source, transmits the infusion auto-program to the infusion pump, and sends a stale auto-program to the infusion pump. The infusion pump receives a manual infusion program, saves and executes the manual infusion program, and compares the stale auto-program to the manual infusion program to identify potential matches between the stale auto-program and the manual infusion program. The infusion pump evaluates the potential matches and determines if the potential matches are within a predefined tolerance, continues to execute the at least one manual infusion program on the infusion pump if the potential matches are within the predefined tolerance, and remotely saves differences in the manual infusion program and the at stale auto-program in a remote server for later analysis.

Abstract: An electronic device and a method of operating the electronic device are provided. The method includes sensing a weight of an intravenous (IV) fluid injected into a user; measuring a time remaining until injection of the IV fluid is completed, based on the sensed weight of the IV fluid; determining whether the measured remaining time is equal to or less than a predetermined value; and transmitting an alarm signal indicating an injection state of the IV fluid to an external device based on a result of the determining.

Abstract: A system and method to configure a rule set used in connection with a medical monitoring system for monitoring patients and patient care equipment, especially medication delivery pumps, based on a variety of conditions and parameters associated with monitored biometric information and equipment information and for providing user-defined responses to those conditions and parameters.

Abstract: A syringe includes a first syringe barrel and a second syringe barrel. Each barrel includes a delivery end to which an end piece with a channel is secured, a piston which is arranged movable in the syringe barrel and can be moved towards the delivery end in order to deliver a fluid located between the delivery end and the piston via the channel. The two syringe barrels are mechanically connected to each other such that the distance between them cannot be changed. At least one of the two end pieces can be secured to the allocated delivery end in different positions for adjustment of the distance between the two channels.

Abstract: The present invention relates to a dual-chamber pack with a first chamber comprising a container; and a second chamber comprising a reservoir, a biphasic connector, a plunger, and a plug with a breakable polymeric membrane. The container of the first chamber is prefilled with a pharmaceutically acceptable vehicle and the reservoir of the second chamber is prefilled with a solid composition of an active ingredient, wherein the solid composition of the active ingredient is mixed with the pharmaceutically acceptable vehicle to form a liquid pharmaceutical composition upon activation of the dual-chamber pack.

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container (16), and a plunger (18) positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source (42) operable to apply pressure on the plunger or the drug container to pressurize the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurized.

Abstract: An automatic injection device configured for injection of a material stored in a syringe into an injection site, the syringe including a generally cylindrical storage container and a piston disposed therewithin, whose exact initial axial position within the container is not predetermined, wherein axial forward displacement of the piston in the container forces the material forwardly out of the container, the automatic injection device including at least one spring drive assembly operative, when actuated, to initially apply a first axial force to the syringe, thereby to axially displace the syringe in a forward direction, and thereafter, responsive to driving engagement with the piston, to apply a second axial force, substantially greater than the first axial force, notwithstanding the fact that the exact axial position of the piston within the container is not predetermined, to the piston, thereby to axially forwardly displace the piston relative to the syringe.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: The present invention relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device. The mechanism includes a housing, a dosing member which during dose setting, dose resetting and dose dispensing rotates relative to the housing between a zero dose position and a maximum dose position, and an insert that is rotationally constrained to the housing. The dosing member and the insert each include at least one abutment feature contacting each other when the dosing member reaches its zero dose position during dose dispensing, and an audible and/or tactile feedback is generated by the contact of the abutment features.

Abstract: An injection device includes a housing, a resilient member adapted to provide a force necessary for ejecting a dose from the injection device, and a dose setting member operatively connected to a dose indicator which is positioned within the housing. The dose setting member and the dose indicator cooperate to set the dose to be ejected from the injection device. The dose indicator, during dose setting, is adapted to undergo a mere rotational movement within the housing and relative to the housing.

Abstract: The invention relates to a safety device (S) for a drug delivery device (1), comprising: —a support body (2) adapted to receive and hold the drug delivery device (1), —a needle shield (8) slidably arranged relative to the support body (2), —an inner locking mechanism (12) arranged inside the needle shield (8) between a front end of the needle shield (8) and a front end of the support body (2) and adapted to lock and unlock the needle shield (8).

Abstract: An automatic injection device including a housing element, at least one resilient element arranged to be located within the housing element, a syringe including at least one syringe piston, a needle guard adapted for selectable positioning with respect to the housing element and a selectable driving element adapted, when actuated, to be driven by the at least one resilient element for initially displacing the syringe relative to the housing element from a non-penetration position to a penetration position and thereafter displacing the at least one syringe piston in the syringe to effect drug delivery and displacing the needle guard into a needle guarding position.

Abstract: An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element.

Abstract: A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit, a waste conduit and/or an energy delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip and a plurality of needles generally positioned within the peripheral lip. The tip also comprises at least one opening in fluid communication with a fluid delivery conduit, at least one opening in fluid communication with a waste conduit and/or an energy contact point in electrical communication with an energy contact point and energy conduit in the main body portion. The plurality of needles may be movable with respect to the peripheral lip through the use of a pneumatic or other force.

Abstract: A dispensing device includes a container with a receiving space containing a dispensable medium extractable via a dispensing element. A control body (19) with a connecting body (11) is longitudinally displaceable in a housing part (9), from an inactive base position to an active extraction position by a rotational movement. A media-carrying connection is created between the receiving space and the dispensing element. A control part of the control body (19) can be attached to a control path (54) of the connecting body (11). When the control body (19) moves rotationally relative to the housing part (9), each control part follows the rotational movement in an axially unchanged manner and brings the connecting body from the base position to an extraction position via each associable control path (54) of the connecting body (11). The control path comprises a slope.

Abstract: A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.

Abstract: A puncture assisting device includes a pair of plate-like pinching portions that face each other, and that are attached to each other so as to be openable and closeable; a biasing portion that biases the pair of pinching portions to be in a closed position; a pair of gripping portions configured to operate the pair of pinching portions to be in an open position; and a rod insertion portion that is disposed between the pair of pinching portions, the rod insertion portion being configured such that a rod portion of a syringe is insertable into the rod insertion portion to widen a gap between the pair of pinching portions.

Abstract: The invention generally relates to catheter systems and methods for guided formation of vascular access sites (such as fistulas and grafts). According to certain aspects, a catheter system for forming a vascular access site include an elongate body comprising a distal end and configured to be inserted into a first vessel. The elongate body includes an exit port along its side that is proximal to the distal end. An imaging assembly is associated with the elongate body and configured to generate image data of the first vessel and a second vessel positioned next to the first vessel. For vascular access formation, a penetrating member of the catheter system extends out of the exit port and through a wall of the first vessel and a wall of the second vessel.

Abstract: A prefilled syringe includes: a syringe barrel including a syringe barrel body and an outer barrel; a cap; a gasket; and a plunger which allows the gasket to slide by pressing a press portion located on the base end of a shaft to discharge a drug solution inside the syringe barrel body. The outer barrel has a window and a mask which hides the inside of the outer barrel on a wall thereof. A part of the shaft has a mark which has a color different from the color of other parts of the plunger. The mark is covered with the mask and is not visually recognizable through the window before discharge of the drug solution. The outer peripheral surface of the mark is visually recognizable through the window along with movement of the plunger when the discharge of the drug solution is completed.

Abstract: A surgical spray instrument is disclosed comprising a main body connectable to a transfer tube; a propellant actuator for selectively releasing propellant from the main body and along the transfer tube and out through a distal end thereof. An ion emitter is arranged along the tube, the ion emitter having an ion emission zone. This enables the directed and concentrated delivery of therapeutic, pharmacological and diagnostic agents to tissues inside or outside of the body. There is further disclosed a surgical assembly for enabling uniform deposition of a particulate material to a surface of an intracorporeal cavity of a patient. The surgical assembly comprises an ion emitter; a dispenser having an outlet locatable within the cavity and for dispensing the particulate material therefrom, and a processor for determining a location of the ion emission zone of the ion emitter in dependence upon the position of the outlet of the distributor within the cavity to provide for the uniform deposition.

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: An improved dry-powder inhalation device having a casing having an air inlet located at a first terminus; a powder delivery port located at a second terminus, which is positioned distal to the air inlet; and an elongated support panel located within an interior of the casing and being fitted within the casing so as to partially rotate therein about a single axis. The support panel has at least one compartment containing dry-powder located proximally to the second terminus, and the casing has a plurality of needle-like structures located proximal to the delivery port and arranged above the dry-powder compartment. The compartment with a dry-powder includes a blister structure encasing the dry-powder, whereby airflow through the device causes the elongated support panel to partially rotate repeatedly within the casing, thereby striking the plurality of needle-like structures and releasing the dry-powder in the airflow.

Abstract: A medicament delivery device comprises a dosing chamber configured to contain dry powder medicament, a transducer and a controller electrically coupled to the transducer. The medicament delivery device is capable of delivering a therapeutically effective dose of dry powder medicament in response to between 2-20 tidal inhalations, the dose preferably having a mass median aerodynamic diameter (MMAD) of about 6 microns or less and a fine particle fraction of at least 30%.

Abstract: A PAP system is adapted for treatment of respiratory disease or sleep disordered breathing. The PAP system includes headgear, a patient interface and a flow generator. The flow generator includes a blower adapted to provide pressurized breathable gas to a patient through the patient interface. The blower is at least partially vibrationally isolated from the patient's head by at least one foam layer mounted within the flow generator to secure the blower. The at least one foam layer is adapted to reduce the amount of transmitted vibration received by the patient. The flow generator further includes a mounting structure limiting an extent of a compression of the at least one foam layer due to the weight of the blower. The mounting structure includes at least one protrusion extending from an interior surface of the flow generator toward the blower.

Abstract: A ventilator includes first and second pathways, a conduit and a controller. The first pathway (120) is configured to supply a first gas and the second pathway (140) is configured to supply a second gas, where the second gas is mixed with the first gas to produce mixed gas having a predetermined percentage of the second gas. The conduit (166) is configured to provide the mixed gas from the first and second pathways to an access port during an inspiratory phase, and to provide discharged gas from the access port to the first pathway during an expiratory phase. The controller (180) is configured to delay supply of the second gas from the second pathway for a delay time in order to maintain the predetermined percentage of the second gas in the mixed gas provided to the access port during a subsequent inspiratory phase.

Abstract: The volume of a pressure equalization balloon is connected to a further volume, the pressure of which is intended to remain as constant as possible. To keep the cuff pressure in the pressure range of between roughly 20 mbar and 30 mbar, the equalization balloon is produced from a thermoplastic polymer (TPE) and is overstretched past the maximum intended control volume before first use and is then relaxed to the range of the control volume.

Abstract: A mask cushion or a mask assembly therewith provides a comfortable and effective seal for provision of a gas therapy by a respiratory treatment apparatus. The mask cushion (102) may be integrated with or coupled to a mask frame. The mask cushion typically includes an inner cushion component (104). The mask cushion also includes a patient facial-contact side portion with a chamber (108) and a barrier (106) to form the chamber that may be flexible. The chamber may serve as an outer layer with respect to the inner cushion component. The chamber may be partially or completely filled with a gas, fluid or gel. The inner cushion may be formed with a soft flexible material such as an elastomer or foam, etc. The barrier may be a membrane and may also be soft flexible material.

Abstract: This invention relates to a respiratory mask for delivering an inhalation fluid to the airways of a wearer. The respiratory mask includes a body of generally concave shape and having a peripheral edge, the body being adapted to provide a cavity in use about the mouth and nose of a wearer such that the inhalation fluid can be inhaled by the wearer from the cavity. The respiratory mask includes a resilient seal formation depending from at least a portion of the peripheral edge. The resilient seal formation includes both an inwardly and outwardly depending lip portion relative to the peripheral edge of the body. The mask may accommodate a range of facial dimensions whilst still retaining an effective seal.

Abstract: An embodiment of the disclosure provides a universal sealing apparatus for one or more cannulas. The apparatus includes a first portion, a second portion, and a third portion. The first and second portions are configured to removably adhere directly or indirectly to a nose. The third portion is coupled to the first and second portions. The third portion removably couples to one or more cannulas and places a force upon a base of flared portions of the one or more cannulas when the first and second portions are adhered to the nose. The force maintains a fluid seal of the one or more cannulas within one or more respective nostrils of the nose.

Abstract: Medical breathing tubes have a tubular body that defines a lumen extending between open terminal ends of the tubular body. An internal form is enclosed within the lumen and supportive of the tubular body. The internal form may be a coated encapsulated internal form where the coating secures the internal form to the tubular body. The internal form may provide for a series of alternative crests and troughs of the tubular body. A patient interface and/or a securement system may be attached to the tubular body.

Abstract: A respiratory assistance apparatus includes a flow generator and a humidifier. The humidifier includes a humidification chamber. The humidification chamber comprises a water tub that is configured to receive a volume of water. A lid is hingedly coupled to the water tub for enclosing a volume contained within the water tub.

Abstract: The invention generally relates to a continuous anesthesia nerve conduction apparatus and method thereof, and more particularly to a method and system for use in administering a continuous flow or intermittent bolus of anesthetic agent to facilitate a continuous or prolonged nerve block. In one embodiment, the apparatus includes a sheath having a proximal end, a distal end and at least one lumen extending from the proximal end to the distal end. The sheath also includes an embedded conductive element for transmitting an electrical signal from a proximal portion of the sheath to a distal portion of the sheath. A cannula is arranged in the at least one lumen of the sheath and has a distal end protruding from a distal portion of the sheath. The cannula is electrically coupled to at least a portion of the embedded conductive element and is configured to provide nerve stimulation.

Abstract: A treatment system includes a delivery device which delivers a combination of a breathing gas and frozen ice or other particles to a patient in order to induce hypothermia. The treatment system also includes a temperature system for measuring the temperature of exhaled gases and a controller which can adjust the duration or rate at which the ice particles are delivered in order to control the patient's core temperature based on the measured exhalation gas temperature.

Abstract: A catheter assembly is disclosed, comprising a catheter, such as a urinary catheter, which at least a partly is provided with a hydrophilic coating. The catheter assembly further comprises a wetting fluid. The receptacle is in direct contact with the hydrophilic coating of the catheter over essentially the entire length of the part of the catheter being provided with the hydrophilic coating. This may e.g. be achieved by using a shrink wrap material. In order to accomplish adequate wetting, channels or the like may be provided on the inner surface of the receptacle or the outer surface of the catheter.

Abstract: A stabilized catheter tube for insertion into a body of a patient. The catheter tube includes a distal portion that remains stable during fluid infusion into the patient, thus reducing or eliminating whipping of the catheter distal tip. In one embodiment, the catheter tube defines at least one lumen and is formed from a tube material that defines a proximal portion and a distal portion of the catheter tube. The catheter tube is configured such that the arithmetic product of an elastic modulus and an area moment of inertia for the distal portion of the catheter tube is greater relative the arithmetic product of an elastic modulus and an area moment of inertia for the proximal portion of the tube. In one embodiment, the catheter tube is operably attached to an implantable access port and includes an enlarged distal portion relative a proximal portion of the catheter tube.

Abstract: Catheters and methods for supporting a guidewire or delivering a radiopaque, diagnostic or therapeutic agent through a vessel stenosis or other tortuous anatomy are disclosed. A catheter can comprise an elongate shaft body and a tip member disposed at a distal end of the shaft body. The shaft body can extend from a proximal end to the distal end and can define an inner lumen. The shaft body can include a liner, a braid member surrounding the liner, a multi-layer coil surrounding the braid member, and a polymer cover surrounding the multi-layer coil. An outer surface portion of the polymer cover can include one or more helical threads, which can be enveloped in an outer wrapper. The tip member can be made from a metal or a polymer. Polymer tip members can include a hard or semi-hard distal tip.

Abstract: An introducer sheath is disclosed having a high centering performance that is relatively easily capable of introducing an elongated body such as a catheter into an appropriate position, and is capable of appropriately maintaining hemostasis and insertibility of a valve body. The introducer sheath includes a tubular member provided with a hollow section through which an elongated body is freely insertable, a hub that includes an inner space which communicates with the hollow section of the tubular member and is provided on a proximal side of the tubular member, a valve body that is placed in the inner space of the hub, and an annular member that contacts with the valve body to fix the valve body to the inner space and includes a through-hole into which the elongated body can be inserted.

Abstract: A single or multiple lumen catheter is disclosed which includes an expandable lumen. The expandable lumen is movable from a collapsed or sealed configuration to an open or expanded configuration. In the open configuration, the expandable lumen is dimensioned to receive a guidewire or stylet or facilitate the introduction of fluids into a patient.

Abstract: A medical system including a catheter containing a mechanical system that is remotely operable uses a sensor to at least partly measure a pose of the catheter and a control system coupled to the mechanical system. The control system has multiple operating modes including one or more holding modes in which the control system operates the mechanical system to maintain a working configuration of the catheter based on feedback from the sensor.

Abstract: A catheter having an internal advancing mechanism that can advance stiffening wires or other devices, has a catheter with a catheter body, a tip section distal the catheter body, a device extending through at least the catheter body, and a control handle proximal the catheter body, where the control handle has an advancing mechanism with a threaded member, an adjustment member, and a guided member to which the device is connected, and the advancing mechanism is configured to advance and retract the device along the catheter body as controlled by a user. Each of the threaded member and the adjustment member has a generally cylindrical configuration. The threaded member has an outer surface configured with a helical guide channel. The adjustment member is configured to guide the guided member to move within the helical guide channel to advance and retract the device. The adjustment member can be rotatable over the threaded member by the user to control advancement and retraction of the device.

Abstract: A catheter holder assembly for selectively holding a portion of a one or more catheter tubes to a head of a user. Comprising head mount assembly, a one or more catheter holders, the one or more catheter tubes, a catheter. The one or more catheter holders comprise a first catheter holder. The one or more catheter holders are attached to the head mount assembly. Head mount assembly is configured to releaseably attach to the head of the user. The one or more catheter holders releaseably hold the one or more catheter tubes. The one or more catheter tubes each comprise the catheter at a first end being a downstream of the one or more catheter holders and an IV bag at a second end being an upstream of the one or more catheter holders. The catheter is configured to attach to a portion of the user at an insertion point.

Abstract: A catheter assembly includes a hollow catheter; a catheter hub configured to fix and hold the catheter; an inner needle including a needle tip and configured to be removably inserted through an inside of the catheter; a needle hub configured to fix and hold the inner needle; and a catheter operation member capable of moving the catheter relative to the inner needle. The catheter operation member includes a holding portion configured to directly hold the catheter in a detachable manner.

Abstract: A method involves puncturing a blood vessel of a patient with the sharp needle point of an inner needle, axially advancing a guide wire operating member connected to a guide wire to axially advance the guide wire relative to the inner needle to move the guide wire along the blood vessel, and axially advancing a catheter operating member connected to a catheter to axially advance the catheter in the distal direction relative to both the inner needle and the guide wire such that the distal end of the catheter is positioned at a target position in the blood vessel.

Abstract: A device for emptying stool from the rectum of a patient by means of a shaft body which is introduced into the bowel via the anus and is able to buckle or fold axially and radially, and which is provided with a dumbbell- or hourglass-shaped balloon body for assuring the transanal positioning of the device. The invention comprising a design of, and choice of material, for the shaft body and the balloon envelope, and by the positioning of the balloon body on the shaft body, wherein the axial deflection of the free forward end of the shaft body is limited and an uncontrolled deflection of the shaft is prevented, and the probability of perforation of the bowel wall under the effect of force acting on the shaft body from an axial direction is reduced by the intestinal tube.

Abstract: An inflation device that may comprise multiple plungers is disclosed. The inflation device may have multiple configurations wherein certain plungers are locked with respect to a body of the inflation device while others are configured to be displaceable within the body. Each plunger may be configured with a different effective surface area, allowing a practitioner to vary the amount of force required to attain certain pressures.

Abstract: A coating apparatus for coating the balloon portion of a balloon catheter is described. The coating apparatus includes a rotatable member in which the catheter portion of the balloon catheter is mounted and fixed, and which causes rotation of the balloon catheter. The apparatus also includes a support member in which the distal tip of the catheter is inserted and free to rotate; and a spray nozzle directing sprayed material on the balloon surface. The inventive configuration of the coating apparatus allows the balloon catheter to be rotated along its axis with insubstantial or no wobble, which significantly improves the quality of the coating applied to the surface of the balloon.

Abstract: A dilation catheter comprises a handle, a guidewire, a dilation catheter, a guidewire movement mechanism, and dilation catheter movement actuator. The guidewire movement mechanism is configured to translate to thereby cause translation of the guidewire relative to the handle. The dilation catheter movement mechanism is configured to translate to thereby cause translation of the dilation catheter relative to the handle. The guidewire movement mechanism also includes a rotation mechanism configured to impart rotation upon the guidewire. The rotation mechanism may include features configured to limit the amount that the guidewire may rotate. The rotation mechanism may also include features configured to convert linear movement of an actuator into rotational movement of the guidewire. The dilation catheter may include features configured to provide for side entry of the guidewire into the dilation catheter.

Abstract: Inventive embodiments disclosed herein include a catheter for dilating a sinus cavity lumen. The catheter includes a guide tube, having a proximal end and a distal end, that terminates in a distal tip; a sleeve member annularly positioned over the guide tube, wherein the sleeve member is movable relative to the guide tube and is capable of being advanced over the guide tube; and a balloon coupled to the sleeve member, wherein the balloon can be extendable and inflated at or beyond the end of the guide tube.

Abstract: Provided are devices for therapeutic interaction with an Abreu brain thermal tunnel (ABTT) terminus. Such devices are configured to provide one or more drugs to an ABTT terminus, and may provide heat to or remove heat from the ABTT terminus while providing the one or more drugs.