Abstract: An ocular portion coupling apparatus includes: a stepped pipe on which lock balls which are pressed against an eyepiece, are slidably arranged; and a rotation ring placed turnably on a ring placing surface, the rotation ring including a cam surface, wherein the stepped pipe includes convex pieces protruding outward from an outer circumferential surface of the large diameter portion, the convex pieces including one planes, the one planes and the ring placing surface sandwiching the rotation ring, and the rotation ring includes: axis direction grooves through which the convex pieces can pass; slide planes on which the one planes are slidably arranged; and restriction portions configured to prevent the convex pieces from dropping out through the axis direction grooves.

Abstract: A multi-focal, multi-camera endoscope having a tip section including a first optical assembly for generating a first image of a body cavity; a second optical assembly for generating a second image of a body cavity; at least one illuminator associated with each of the first optical assembly and second optical assembly; and a processing system configured to: zoom the first optical assembly and thereby generate a zoomed first image in place of the first image; and automatically cause a physical display to eliminate a display of the second image and to only display said zoomed first image. To eliminate the display of the second image, the processing system reduces a power supply to the second optical assembly, reduces an illumination intensity of an illuminator associated with the second optical assembly or causes the physical display to power off, darken, or blacken.

Abstract: An inserting instrument includes a first flexible tube section having a flexibility lower than a spiral tube, a second flexible tube section having a flexibility lower than the spiral tube and equal to or higher than the first flexible tube section in a state where the second flexible tube section is not covered with the spiral tube. The flexibility of the second flexible tube section is lower than that of the first flexible tube section when the second flexible tube section is covered with the spiral tube. The inserting instrument includes a third flexible tube section provided on the proximal direction side with respect to the second flexible tube section and having a flexibility lower than the first flexible tube section.

Abstract: An actuating member for making a flexible elongate member for medical use perform a predetermined action includes a push/pull member, an operating member, and an advancing member. The push/pull member includes a first moving portion and a second moving portion, which are movable relative to each other. The push/pull member is pushed/pulled in conjunction with a movement of the first moving portion and the second moving portion. The operating member effects the movement of the first moving portion and the second moving portion. The advancing member includes a narrowed portion that moves the first moving portion and the second moving portion in conjunction with an operation of the operating member. The push/pull member makes the elongate member perform at least one of (i) an advance/retraction action and (ii) a bending action by transmitting the movement of the first moving portion and the second moving portion to the elongate member.

Abstract: A device, including a straight support element, a curved support element slidably coupled to the straight support element, and a rigid straight support element slidably coupled to the curved support element, the straight support element having a first rigidity, the curved support element having a curved portion having a second rigidity greater than the first rigidity, the rigid straight support element having a third rigidity greater than the second rigidity, when the rigid straight support element overlaps the curved portion of the curved support element an overlapped portion of the curved portion conforms to a straight shape of the rigid straight support element, when the curved portion overlaps the straight support element, an overlapped portion of the straight support element conforms to a curved shape of the curved portion, the curved portion having a rectangular cross section.

Abstract: Systems, devices and methods for producing registered images of a body lumen are provided. The system includes a first imaging device having an imager positioned at a distal end thereof, said first imaging device configured to produce a first image of a body cavity; and an imaging system, including a second imaging device having an imager positioned at a distal end thereof and configured to be positioned approximate to said imager of said first imaging device within said body cavity and configured to produce a second image; an elongated member configured to contain said second imaging device; and at least one marker configured to produce registration information in the first image and the second image.

Abstract: Bilateral illumination attachment for dental camera is a light source that is reversibly attachable to any dental camera. Bilateral illumination attachment for dental camera has two light sources that directly face each other. When properly attached to a dental camera, bilateral illumination attachment for dental camera effectuates sub-enamel illumination or bilateral illumination of a tooth, so that the dental camera may capture a photo or image of the illuminated tooth. Bilateral illumination attachment for dental camera has a specially shaped rigid body that makes a slip-fit, press-fit, or snap-fit with the exterior surface of any dental camera. The distal end of specially shaped rigid body is sterilizeable. Bilateral illumination attachment for dental camera has a plurality of replaceable tooth cups where each tooth cup contains the two light sources. Replaceable tooth cups are placed on the tooth to effectuate sub-enamel illumination or bilateral illumination. Replaceable tooth cups are sterilizeable.

Abstract: A system for mounting a retractor tube to a spine without a guidewire is disclosed. The system includes an awl, a first dilator configured to be advanced over the awl, a retractor tube configured to be advanced over the first dilator, wherein an outer surface of the retractor tube defines a plurality of channels, and a plurality of pins adapted to be received within the plurality of channels, wherein the plurality of pins secure the retractor tube to the at least one vertebral body of the spine. A method for selectively mounting a retractor tube to a spine without a guidewire is also disclosed.

Abstract: In a method for the acquisition of optical coherence tomography image data of retina tissue of an eye (99) of a human subject using an acquisition device comprising an imaging optics (2), a first image associated with a baseline relative positioning of the eye (99) of the human subject with respect to the imaging optics (2) is acquired at a first point in time. The baseline relative positioning is stored. At a second point in time being different from the first point in time, the baseline relative positioning of the same eye (99) of the same human subject with respect to the imaging optics (2) is re-established and a second image is acquired. For re-establishing the positioning, a present relative positioning of the eye (99) of the human subject with respect to the imaging optics is determined based on a video image of an iris region of the eye.

Abstract: In one embodiment, a portable pupillometer including a testing compartment, at least one ocular disposed on the testing compartment, two or more light sources disposed in the testing compartment and forming a plurality of visual stimuli for a subject looking through the at least one ocular, at least one camera configured to capture images of a pupil of the subject via infrared detection, the images indicating pupillary responses to the two or more light sources, and an interface for connection with a computing device external to the pupillometer, the interface adapted to (i) provide, to the computing device, images from the at least one camera, and (ii) receive, from the computing device, control signals for controlling the plurality of light sources.

Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

Abstract: A wide field fundus camera is disclosed to implement multiple illumination beam projectors and to capture multiple retinal images at a various viewing angles to mimic wide field retinal examination with an indirect ophthalmoscope. The wide field fundus camera may incorporate a consumer image recording device with fast auto focusing so as to make the device quick to respond and easy to use. The wide field fundus camera may include narrow and broad slit beam illuminations to enhance autofocusing and imaging through less transparent crystalline lens and through haze due to Purkinje reflections from crystalline lens surfaces. Control of multiple illumination beam projectors in a programmable manner can be used to assess alignment of each illumination beam projector with the eye and to capture said multiple retinal images. Furthermore, a method is disclosed to montage said multiple retinal images into a single montage and to remove haze and reflections.

Abstract: A non-sliding, non-sutured hands-free contact lens assembly for ophthalmic procedures utilizes a number of microstructures strategically placed on the bottom of either the contact lens or the bottom of a contact lens holder ring. After the contact lens, or the contact lens assembled with the contact lens holder ring, is placed on the cornea of the eye and centered, a surgeon applies downward pressure either on the contact lens itself or on the lens holder ring. This secures the lens assembly to the cornea due to increased friction between the microstructures and the tissues of the eye when the microstructures penetrate through the tear film and, optionally, viscous solution film and into the contact with superficial layer of cornea or other parts of the eye, thus temporarily anchoring the contact lens, or lens holder, to the desired surgical site.

Abstract: According to one embodiment, an ophthalmologic apparatus includes an optical system, a support, a drive unit, an alignment optical system, two or more imaging units, an analyzer, and a controller. The optical system acquires data of an eye. The support is configured to support the face of a subject. The drive unit moves the optical system and the support relative to each other. The alignment optical system projects an indicator for performing alignment of the optical system with respect to the eye onto the anterior segment of the eye. The imaging units photograph the anterior segment of the eye, onto which the indicator is being projected, substantially simultaneously from different directions. The analyzer analyzes two or more photography images captured substantially simultaneously by the imaging units to specify the position of the eye. The controller controls the drive unit based on the position specified by the analyzer.

Abstract: The present invention provides a method for assessing bowel function in a patient, comprising providing the patient with a numeric analog scale for at least one parameter which is a measure of bowel function; causing the patient to indicate on the numeric analog scale the amount and/or intensity of the parameter being experienced; and observing the amount and/or intensity of the at least one parameter indicated on the numeric analog scale in order to assess bowel function.

Abstract: A spectrometer includes an illuminating section; a receiving section configured to detect radiation reflected from an object including an optically inhomogeneous scattering medium; a hardware section configured to obtain a solution of an inverse problem to reconstruct an absorption spectrum of the optically inhomogeneous scattering medium, wherein the illuminating section includes at least one light-emitting diode source, a radiation spectral curve of which is divided, by at least two spectral filters having different spectral transmission curves, into at least two spectral regions, to form an equivalent radiation spectrum from at least two spectral sources, and wherein the hardware section applies the solution of the inverse problem based on information about a spectral content of the radiation of the illuminating section, a signal obtained in a form of a response from the optically inhomogeneous scattering medium, and a spectral sensitivity curve of the receiving section.

Abstract: A photobiomedical measurement apparatus includes a measurement point determination module to determine a specified position in a brain surface image as a measurement point by designating the specified position in the brain surface image with an input device, an estimated point determination module to determine a specific position in a scalp surface image as an estimated point(s) based on the measurement point (m) and displaying an image of the estimated point (s); and a position-guiding module that displays, on the scalp surface image pathway images (L1, L2), which represent the shortest pathways along the scalp surface between the estimated point (s) and reference points on the scalp surface image corresponding to reference points of the subject.

Abstract: Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at a plurality of temporal delays. A cross-correlation function of at least one of amplitude, phase and intensity of a scattered optical field is derived for a plurality of depths relative to the specified surface. A mean cross-correlation function is then derived for each depth and fit to obtain a diffusion coefficient, from which a relative viscosity characterizing the fluid is derived.

Abstract: Proposed is a method for in-line testing and surface analysis of test material with participation of Raman spectroscopy wherein the apparatus has a column with a plurality of test units at least one of which is a wear test unit and another is a Raman spectrometer. The sample is located on a rotary table under the test units. By sequentially removing the material of the sample to a predetermined depth and then conducting the surface analysis with the use of the Raman spectrometer, it becomes possible to analyze distribution of the material components in the depth direction from the surface of the sample.

Abstract: In an example, an apparatus includes an elongated assembly, at least a portion of which is sized, shaped, or otherwise configured to be inserted into a human body to measure a physiological parameter at an internal location within the body. The elongated assembly can include an elongated member. The elongated assembly can include an optical fiber pressure sensor, located at a distal portion of the elongated member. The elongated assembly can include a housing disposed about the optical fiber pressure sensor. The elongated assembly can include a guidewire tube, coupled to the housing, the guidewire tube defining a receptacle sized and shaped to accept a guidewire to permit the distal portion of the elongated member to slide along the guidewire during insertion of the elongated assembly into the human body.

Abstract: In an embodiment, an apparatus for opto-acoustic imaging includes a first contact area adapted to apply a first pressure to a surface of an imaging volume of a subject and a second contact area adapted to apply a second pressure to the surface. The second contact area is configured to provide decreased blood exit from the imaging volume by restricting flow relative to the first contact area. An optical energy output port is provided to illuminate the imaging volume to produce opto-acoustic signals from an absorbed optical energy of blood in the imaging volume. The opto-acoustic signals are detected by one or more ultrasound transducers and processed by a processor to generate images of the volume. An image generated by processing the detected opto-acoustic signals is output on a display.

Abstract: The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.

Abstract: Systems and methods for monitoring various physiological and environmental factors, as well as systems and methods for using this information for a plurality of useful purposes, are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed. This information is then used to support a variety of useful methods, such as clinical trials, marketing studies, biofeedback, entertainment, and others.

Abstract: A method and system for determining fractional flow reserve (FFR) for a coronary artery stenosis of a patient is disclosed. In one embodiment, medical image data of the patient including the stenosis is received, a set of features for the stenosis is extracted from the medical image data of the patient, and an FFR value for the stenosis is determined based on the extracted set of features using a trained machine-learning based mapping. In another embodiment, a medical image of the patient including the stenosis of interest is received, image patches corresponding to the stenosis of interest and a coronary tree of the patient are detected, an FFR value for the stenosis of interest is determined using a trained deep neural network regressor applied directly to the detected image patches.

Abstract: Systems and methods are provided for assessing patient blood flow using video image processing. According to one aspect, a method of analyzing at least one blood flow characteristic of a patient includes capturing a video including a plurality of frames of an arterio-venous (AV) fistula on the patient; amplifying motion in the video to produce a motion-amplified video; determining a difference in intensity between consecutive frames in the motion-amplified video to produce a time-function of an amplitude of the optic flow representing movement in an area of interest on the patient; and determining the at least one blood flow characteristic of the patient based on the time-function.

Abstract: MRI techniques seek to simultaneously measure physiological parameters in multiple directions, requiring the application of multiple encoding magnetic field gradient waveforms. The use of multiple encoding waveforms degrades the temporal resolution of the measurement, or may distort the results depending on the methodology used to derive physiological parameters from the measured data. The disclosed Direct Inversion Reconstruction Method (DiR) provides distortion-free velocity images with high temporal resolution, without changing the method of acquiring the phase data. The disclosed method provides a more stable and accurate recovery of phase-based dynamic magnetic resonance signals with higher temporal resolution than current state-of-the-art methods.

Abstract: Provided is a highly reliable technique for the evaluation of ischemic conditions. A preferred embodiment is a nuclear medicine measurement protocol in which the administration of a radiopharmaceutical agent and radiation measurement are performed twice at rest and under stress. In the nuclear medicine measurement protocol, radiation collection is performed without radiopharmaceutical agent administration before the second radiopharmaceutical agent administration, and the result is used to correct the nuclear medicine measurement result after the second radiopharmaceutical agent administration.

Abstract: A system for managing care of a person receiving emergency cardiac assistance includes one or more capacitors arranged to deliver a defibrillating shock to a person; one or more electronic ports for receiving a plurality of signals from sensors for obtaining indications of an electrocardiogram (ECG) for the person; and a patient treatment module executable on one or more computer processors using code stored in non-transitory media and to provide a determination of a likelihood of success from delivering a future defibrillating shock to the person with the one or more capacitors, using a mathematical computation applied to a vector value defined by signals from at least two of the plurality of signals.

Abstract: Disclosed herein are techniques for graphically indicating aspects of rotors (such as pivot points of rotors) associated with atrial or ventricular fibrillation. Embodiments can include receiving, using a processor, an electrogram for each of a plurality of spatial locations in a heart, each electrogram comprising time series data including a plurality of electrical potential readings over time. Embodiments can also include generating, from the time series data, an entropy dataset including a plurality of Shannon entropy values corresponding to the plurality of spatial locations in the heart. Also, examples can include generating, from the entropy dataset, an entropy map including a plurality of graphical indications of the Shannon entropy values at the plurality of spatial locations in the heart, wherein the entropy map can include an image of the heart and graphical indications of locations of aspects of rotors in the heart (such as pivot point of rotors).

Abstract: The present disclosure provides a GPU-based parallel electrocardiogram signal analysis method, comprising: performing a filtering process of electrocardiogram signals through a long interval artifact removal and a short interval artifact removal; performing a QRS detection of the filtering-processed electrocardiogram signals through an R-wave position extraction, a QRS complex start and end positions extraction and a QRS complex width extraction; performing an abnormal waveform classification of the QRS-detected electrocardiogram signals through template creation; wherein at least one of the long interval artifact removal, the short interval artifact removal, the R-wave position extraction, the QRS complex width extraction and the creation template is performed by a multiple threads at a GPU device side in parallel, any thread being read through its unique index number to process corresponding data.

Abstract: A breast cancer imaging device with microwave surface impedance is a device which is used for imaging tumors in breast tissue using harmless electromagnetic waves in microwave band. It performs this function by using harmless electromagnetic waves without using X-ray. Thus, it can be performed in desired frequency, as many times as desired. Since compressing the breasts is no longer required, it is not a painful imaging process for the patient; moreover, it does not fail to detect the tumors that are close to the rib cage.

Abstract: A wound measurement and tracking system includes a surface measurement indicator where the surface measurement indicator is configured to collect wound information from a wound. A transmitter device is provided that is connected with the surface measurement indicator and is configured to transmit wound information to a data processor. A tunneling depth indicator is provided where the tunneling depth indicator measures tunneling and undermining of the wound. A transmitter device is connected with the tunneling depth indicator that is configured to transmit tunneling and undermining information from the wound to a data processor. And a data processor is provided that is conformed to connect with both of the transmitter devices where the data processor includes data processing software configured for comparison and analysis of wound information.

Abstract: A cryogenic cooling apparatus comprises a supply gas line and a return gas line adapted to be coupled to a compressor. A coupling element is positioned in gaseous communication with the supply and return gas lines, the coupling element being adapted in use to supply gas to a mechanical refrigerator so that the pressure of said supplied gas is modulated by the coupling element in a cyclical manner. A sensing system is used to monitor the operational state of the mechanical refrigerator and a control system modulates the frequency of the cyclical gas pressure supplied by the coupling element in accordance with the monitored operational state. The mechanical refrigerator has a first cooled stage and a second cooled stage, the second cooled stage being adapted to be coupled thermally with target apparatus to be cooled.

Abstract: An MRI prep scan acquires plural sets of echo signals at a plurality of cardiac time phases which are mutually different from each other for each slice and used to generate a plurality of respectively corresponding prep images. Reference information is acquired and displayed for determining a first cardiac time phase and a second cardiac time phase on the basis of the prep images. The first and second cardiac time phases are set in response to an operator's specification. An imaging scan section for acquiring imaging echo signals by performing an imaging scan is performed upon each of the first and second cardiac time phases to acquire imaging echo signals. A first image is generated based on an echo signal of the first cardiac time phase and a second image is generated based on an echo signal of the second cardiac time phase. A differential image is acquired by calculating a difference between the first image and the second image.

Abstract: An elongate medical device includes a sensor configured to detect one or more characteristics of an electromagnetic field in which the device is disposed. The sensor includes an electrically-insulative substrate, rectangular in shape, and a patterned, conductive trace disposed on the substrate. The patterned trace includes a plurality of diagonal sections parallel to one another, arranged with a relatively low pitch. The substrate is wrapped into a cylindrical shape thereby forming a three-dimensional spiral capable of functioning as a micro-electromagnetic sensor. A medical positioning system is responsive to the signal from the sensor to determine a position and/or orientation of the sensor.

Abstract: A surgical navigation system comprising a signal receiver communicatively coupled to a primary processor, the primary processor programmed to utilize a sequential Monte Carlo algorithm to calculate changes in three dimensional position of an inertial measurement unit mounted to a surgical tool, the processor communicatively coupled to a first memory storing tool data unique to each of a plurality of surgical tools, and a second memory storing a model data sufficient to construct a three dimensional model of an anatomical feature, the primary processor communicatively coupled to a display providing visual feedback regarding the three dimensional position of the surgical tool with respect to the anatomical feature.

Abstract: A system, method, and apparatus is provided for estimating a risk of falls from pressure sensor data and inertial sensor data. A classifier function may be generated to relate the inertial sensor and the pressure sensor data with the falls risk (e.g., falls risk or prospective falls data) of the person who generated the pressure sensor data and inertial sensor data. The classifier function may be used to predict a person's risk of falls based on inputs of pressure sensor data and inertial sensor data. Separate classifier functions may be generated for men and women, or separate classifier functions may be generated for patients who closed their eyes while data was being collected and for patients who opened their eyes while data was being collected.

Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.

Abstract: The invention relates to a system and method for measuring the biomechanical state of a subject using various sensors simultaneously with providing the subject with visual exercises for rehabilitation and assessment of disequilibrium, balance and motion disorders. The biomechanical state of a subject is measured during the subject's performance of a predetermined task. Such measurements are useful for the assessment of disequilibrium, balance and motion disorders and are also useful for the determination of therapeutic application of vibrotactile, auditory, or visual feedback to a subject during the subject's attempt to perform a predetermined task. An intelligent controller compares the subject's biomechanical state to a predetermined parameter to determine a variance. If the variance exceeds a threshold, feedback in the form of visual feedback, vibrotactile feedback or auditory feedback may be provided to the subject as a therapeutic means for enabling the subject to compensate for disorder effects.

Abstract: A hearing test system comprising an computerized device (100) having an electro-acoustical output transducer (104) and a graphical user interface (102) and further being adapted to estimate a hearing loss of an individual test person. The invention also relates to a non-transitory computer readable medium carrying instructions which, when executed by a computer, cause a hearing loss of an individual test person to be estimated and a method of estimating a hearing loss.

Abstract: We disclose a system which may be used to analyze data collected from a customized test strip. The customized test strip may include a set of reaction pads which are selected to address the medical needs of a specific user. The system may include a data analysis platform which analyzes the data and proposes a second customized test strip. The second test strip may comprise of a set of reaction pads that the data analysis platform selects for the user based on the analysis of the first customized test strip. The data analysis platform may propose that additional diagnostic metrics be collected from the user to assist in diagnosis. The customized test strips and the additional diagnostic metrics may be within a medical toilet.

Abstract: The invention addresses confounding difficulties involving continuous sweat analyte measurement. Specifically, the present invention provides: at least one component capable of monitoring whether a sweat sensing device is in sufficient contact with a wearer's skin to allow proper device operation; at least one component capable of monitoring whether the device is operating on a wearer's skin; at least one means of determining whether the device wearer is a target individual within a probability range; at least one component capable of generating and communicating alert messages to the device user(s) related to: wearer safety, wearer physiological condition, compliance with a requirement to wear a device, device operation; compliance with a behavior requirement, or other purposes that may be derived from sweat sensor data; and the ability to utilize aggregated sweat sensor data that may be correlated with information external to the device to enhance the predictive capabilities of the device.

Abstract: A rectangular parallelepiped-shaped cartridge main body having a protective cap removably attached to a first end side thereof has a puncture needle retainer that retains a puncture needle provided at the back of a puncture opening provided on the first end side of the cartridge main body such that the puncture needle is slidable toward the puncture opening. Furthermore, a sensor unit having a depositing opening is provided on the first end side of the cartridge main body. The sensor unit has an introduction promoting hole that communicates with an introduction channel communicating with the depositing opening and that opens to the surface of the cartridge main body. The protective cap is provided with a puncture needle protector that covers the puncture needle, a sensor protector that covers the depositing opening of the sensor unit, and a sensor protector that covers the introduction promoting hole.

Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: Systems, methods, and devices of the various embodiments provide a pulse oximeter capable of taking blood oxygen readings based on readings from an accelerometer. The various embodiments may provide an electronic patch including a pulse oximeter and accelerometer connected to a processor, wherein the processor is configured with processor executable instructions to control the operation of the pulse oximeter based at least in part on data received from the accelerometer. In various embodiments the electronic patch may further include a coin cell battery, or other low power source, that may power the pulse oximeter.

Abstract: A tissue oximetry system employing diffuse optical spectroscopy includes an optical subsystem and an electronics and processing subsystem, together generating modulated optical signals processing a response optical signal in order to obtain measurements of blood oxygen values for a tissue from per-wavelength absorption values. Signal sources generate RF modulation signals, and ADC circuitry generates streams of digital sample values from analog detection signals.

Abstract: Embodiments of the present disclosure relate to reusable medical sensors. According to certain embodiments, the medical sensor may include a sensor housing, an emitter disposed in the sensor housing, the emitter being configured to direct light through the tissue of a patient, and a detector disposed in the sensor housing, the detector being configured to detect light from the emitter after the light has passed through the tissue of the patient and to convert the detected light to an electrical signal. The sensor may also include a dye disposed in the sensor housing, wherein the dye is configured to exit the sensor housing when the sensor housing is damaged and is within a solution.

Abstract: An apparatus for eliciting a blood sample comprises a housing, an aperture in a wall of the housing, an aperture cover moveable between a first position in which the aperture is covered and a second position in which the aperture is uncovered, the aperture cover comprising a sealing member configured to seal the aperture on a first side of the wall when the aperture cover is in the first position and a user-contactable part extending from the sealing member through the aperture to the second side of the wall and configured to allow a user to move the aperture cover between the first and second positions.