Abstract: A method for suppressing sensor noise in a spatially oversampled sensor array includes receiving spatially oversampled multi-channel sensor data from a region of interest and building a spatial model from the data for essential spatial degrees of freedom. The method further includes decomposing the data into the underlying spatial model to obtain associated amplitude components containing a mixture of original temporal waveforms of the data and, for each channel of the multi-channel sensor, estimating time-domain amplitude components using cross-validation. Next, for each channel, based on the estimated time-domain amplitude components, sensor noise and/or artifacts for that channel are identified. Finally, for each channel, the identified sensor noise and/or artifacts can be suppressed from the data.

Abstract: System and methods that cancel artifacts of stimulation signals from neural signals are disclosed. In several embodiments, the systems and methods determine a threshold value for the neural signal in the absence of artifacts. The threshold value can then be used to detect an artifact in received neural signals. In a number of embodiments, a template can be used to cancel an artifact from a neural signal in response to the neural signal being greater than the threshold value.

Abstract: A heart monitoring device comprises an enclosure with various sensors and components. The enclosure has a first groove on a top surface, sized to fit a phalange of a subject's right hand. When the device is held with the corresponding phalange keyed into the first groove, the device is in a proper orientation for recording the subject's heart activity. The device includes a plurality of electrodes configured to create one or more electrical circuits across a human heart. The electrodes include a right thumb electrode placed on a side of the enclosure for coupling to the subject's right thumb and an upper chest electrode and a lower chest electrode placed on a bottom surface of the enclosure for coupling to the subject's chest. The heart monitoring device also has a plurality of pulse oximeters placed in the first groove and configured to measure blood oxygen levels of the corresponding phalange.

Abstract: Certain aspects of the present disclosure relate to a method for compressed sensing (CS). The CS is a signal processing concept wherein significantly fewer sensor measurements than that suggested by Shannon/Nyquist sampling theorem can be used to recover signals with arbitrarily fine resolution. In this disclosure, the CS framework is applied for sensor signal processing in order to support low power robust sensors and reliable communication in Body Area Networks (BANs) for healthcare and fitness applications.

Abstract: A method of diagnosing a disorder includes obtaining a medical image of a subject. A Helmholtz Minimum Free Energy is computed from the medical image. A negative slope of the Helmholtz Minimum Free Energy is determined, from which a glial force is computed. The existence of a disorder in the subject is diagnosed if a value of the glial force is within a predetermined range. The disorder can be, for example, a brain disorder, such as Alzheimer's disease, Parkinson's disease, and/or schizophrenia. Other examples of disorders are epilepsy and rheumatoid arthritis. The subject can be, for example, a human subject.

Abstract: A method and device for differentiating heart failure risk scores that includes determining receipt of a current data transmission and acquiring patient metrics from a remote monitoring device, determining a daily heart failure risk score for each day occurring during a time period from a previous received data transmission to the current received data transmission based on the acquired patient metrics, and determining a maximum daily heart failure risk score of the determined daily heart failure risk scores during a lookback window prior to the current received data transmission. A heart failure risk score is determined for the received data transmission based on the determined maximum daily heart failure risk score, and a heart failure risk score alert is determined for the received data transmission based on the proximity of the determined maximum heart failure risk score and the current received data transmission.

Abstract: A method for predicting a future dental situation for a patient. Acquiring historical data including at least: previous time point and context parameter values. Acquiring at a time point all the data related to the current dental situation, including at least: the current time point, context parameter values at the current time point, statistical analysis of the historical data and the current data, so as to predict, at a future time point, at least one future dental situation for the current patient. Depending on the future dental situation, (re)evaluation of the benefit of an orthodontic treatment. Steps may include creating a three-dimensional digital reference model, acquiring at least one two-dimensional image, analysing each updated image and creation, searching, for each updated image, and collecting data relative to the updated reference model and relative to the orthodontic appliance.

Abstract: A method for analyzing heart rate variability, and an apparatus and use thereof, the method for analyzing heart rate variability including collecting ECG data in vitro; digitizing and denoising the ECG data; forming the processed ECG data into a sinus NN interval sequence; selecting sinus NN interval data of 4 hours in an awake state; performing MSE calculation on the sinus NN interval sequence of 4 hours in an awake state; and extracting parameters representing the complexity of a heart rate by using MSE curves. The present invention may provide accurate and efficient screening for drug-refractory epilepsy patients who are suitable for vagus nerve stimulation surgery, thus avoiding unnecessary expenses, and avoiding missing the most opportune moment for treatment. At the same time, patients suitable for VNS surgery are selected by using MSE complexity feature parameters of ECG, thus improving the overall efficacy of VNS therapy.

Abstract: Apparatus and methods for detecting onset of cardiac arrest utilizing a perfusion monitor. Detecting cardiac arrest comprises transmitting a signal toward a user to interact with the skin of the user, receiving a reflection of the signal, generating a photoplethysmogram, and processing the photoplethysmogram to detect whether the user is experiencing cardiac arrest.

Abstract: The invention relates to a user interface of a medical diagnosis system that has at least one evaluation computer and data output means for outputting data to a user in the form of at least one image display device, wherein the user interface can be supplied in real time with EIT data from an electrical impedance tomography (EIT) system in operation on a patient and with ventilation data from an artificial respiration system in operation on the patient, wherein the user interface is in the form of a clinical user interface that is configured, by virtue of its evaluation computer, for real-time data processing of supplied EIT data and ventilation data, wherein the user interface is configured, by virtue of its evaluation computer, to take the supplied EIT data and ventilation data for the different lung areas of the patient that are recorded by the EIT system as a basis for respectively establishing whether there is a volume trauma, an atelaclasis or a normal functional state of the lung in the respective lung

Abstract: Handheld patient-monitoring device is provided that includes a touchscreen having a display area. The touchscreen is configured to present a first chart section in the display area of the touchscreen. The device is also configured to detect an input gesture on the touchscreen that is indicative of a swipe along the touchscreen. The device is also configured to replace, in response to detecting the input gesture, the first chart section with a second chart section such that the second chart section is presented in the display area and the first chart section is not presented in the display area. The second chart section has at least one parameter region that displays information relating to a respective patient parameter. Replacement of the first chart section with the second chart section is visually indicated to the user.

Abstract: Systems and methods are provided for classifying a tissue mass as malignant or benign. The method includes identifying a region of interest in the tissue mass in computed tomography (CT) imaging data, segmenting the CT imaging data to delimit at least a portion of the tissue mass into image segments, extracting a set of radiomic parameters indicative of the tissue mass. The set of radiomic parameters may include tissue mass location, tissue mass shape, tissue mass surface characteristic, or tissue mass texture distribution indicative of the amount of image segments identified.

Abstract: The disclosure relates to a system and method for reconstructing a PET image. The method may include: obtaining PET data relating to an object collected by a plurality of detector units; determining functional status of the plurality of detector units; generating reconstruction data based on the functional status of the respective detector units and the PET data; and reconstructing a PET image based on the reconstruction data.

Abstract: A system, and method, for quantitatively mapping of mitochondrial membrane potential of a tissue in a subject is provided. In some aspects, the provided method includes administering to the subject a detectably effective amount of a tracer as an emission tomography imaging agent; acquiring, using an emission tomography system, emission tomography data associated with the tissue; analyzing the emission tomography data to determine a concentration distribution of the tracer within the tissue; correlating the concentration distribution of the tracer with the membrane potential of the tissue; determining, using the correlating step, a membrane potential distribution of the tissue; and generating a report indicating the membrane potential distribution of the tissue.

Abstract: A diagnostic support suitable to be attached to a patient includes a band suitable to be wrapped around and tightened onto a portion of the patient corresponding to an area of interest of the patient and an air space incorporated in the band and suitable to expand so that, when the band is tightened onto the portion of the patient, the air space compresses and stiffens the portion of the patient.

Abstract: A multiple frame imaging system comprising: radiation source; a detector having an input area; a monitor configured to display detected images; means for determining at least one Region of Interest (ROI) of an object on the displayed image; and a collimator comprising means for projecting the at least one region of interest (ROI) on at least one selected fraction of the input area exposed by said x-ray source, the collimator comprising at least three essentially non-overlapping plates mounted in a plane generally parallel to the detector input surface plane, wherein each plate comprises a first edge in contact with an edge of a first neighboring plate and a second edge adjacent to said first edge in contact with an edge of a second neighboring plate; and means for moving each one of the plates.

Abstract: A radiological imaging device including a gantry suitable to perform the radiological imaging. The gantry includes a source suitable to emit radiation and a detector suitable to receive the radiation. The radiological imaging device further includes a control station suitable to control the functioning of the source and the detector. Also, the radiological imaging device includes an articulated arm suitable to move the gantry in relation to the control station to define various configurations. These configurations include an operating configuration wherein the gantry is distanced from the control station and a rest configuration wherein the gantry is alongside the control station limiting the overall dimensions of the device.

Abstract: A mobile radiation image capturing system includes a radiation generation unit that generates X-ray radiation; a mobile carriage on which the radiation generation unit is mounted; a drive unit that moves the carriage by linear motion in two dimensions and/or by rotation; at least one detection unit that captures a radiation image of an object; at least one sensor unit that determines an orientation and/or a position of the radiation generation unit and the detection unit relative to each other; at least one output unit that output information to a user; and a processing unit that, based on the orientation and/or position of the radiation generation unit and the detection unit relative to each other, determines whether the radiation generation unit and the detection unit have a predetermined orientation and/or position relative to each other and, if not, determines a positioning information on how to move the carriage and/or the radiation generation unit.

Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.

Abstract: In a method for diagnosing and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a larger lesion curvature to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a smaller lesion curvature is to be treated next, then treating the lesions substantially continuously.

Abstract: Methods of diagnosis, prognosis, and treatment of a neurological disease using cribriform plate morphology are provided.

Abstract: A method of providing by a diagnostic medical imaging device, medical image data representing a diagnostic medical image of the tissue of the patient.

Abstract: A medical X-ray CT imaging apparatus includes an X-ray generator that generates a cone beam, an X-ray detector, a support that supports the X-ray generator and the X-ray detector while the X-ray generator and the X-ray detector are opposed to each other, a turning drive unit that turns the X-ray generator and the X-ray detector, which are supported by the support, an imaging information receiving unit, and an X-ray output condition setting unit. The imaging information receiving unit receives an imaging area setting relating to at least one of a size of an imaging area, an imaging purpose, and an imaging region. The X-ray output condition setting unit automatically sets an output condition of the X-ray generator according to at least one of the size of the imaging area, the imaging purpose, and the imaging region, which are received by the imaging information receiving unit.

Abstract: A radiography guide system includes a patient image providing unit for providing, on a screen, one piece of information among information on the position where a virtual patient is to be placed, a radiographic direction, and a radiographic angle, and a patient image which represents, as a three-dimensional image, the virtual patient's posture corresponding to a viewing angle, and an overlay image providing unit for generating an external image which represents, as a three-dimensional image, the appearance of the virtual patient's body according to the position information, the radiographic direction, and the radiographic angle, an internal image which represents the skeleton structure of the body as a three-dimensional image, and a radiographic image of the body. The overlay image providing unit provides, on the screen, an overlay image which overlappingly represents the internal image, the external image, and the radiographic image in the state where the images are registered.

Abstract: A radiation image capturing system includes a processing unit that determines at least three distances between at least one first distance sensor provided at a radiation generation unit and at least three second distance sensors provided at a detection unit based on one or more signals emitted by the first distance sensor, and that determines an orientation of the radiation generation unit and the detection unit relative to each other based on inclination information provided by a first sensor unit provided at the radiation generation unit and a second sensor unit provided at the detection unit. Alternatively, the processing unit determines distances between at least three first distance sensors provided at the radiation generation unit and at least three second distance sensors provided at the detection unit based on signals emitted by the at least three first distance sensors to determine an orientation of the radiation generation unit and the detection unit relative to each other.

Abstract: A system and method for quantitatively assessing a press fit value (and provide a mechanism to evaluate optimal quantitative values) of any implant/bone interface regardless the variables involved including bone site preparation, material properties of bone and implant, implant geometry and coefficient of friction of the implant-bone interface without requiring a visual positional assessment of a depth of insertion. The following description is presented to enable one of ordinary skill in the art to make and use the invention and is provided in the context of a patent application and its requirements.

Abstract: An ultrasound imaging apparatus includes a probe configured to receive ultrasound data from a lung of a fetus; a processor configured to obtain Doppler data based on the ultrasound data, to measure a value about at least one parameter used to estimate lung maturity of the fetus, and to estimate the fetal lung maturity by using the measured value about at least one parameter; and a display configured to display a result of estimated lung maturity.

Abstract: For cardiac flow detection in echocardiography, by detecting one or more valves, sampling planes or flow regions spaced from the valve and/or based on multiple valves are identified. A confidence of the detection may be used to indicate confidence of calculated quantities and/or to place the sampling planes.

Abstract: The invention is a device, system, and method for monitoring function of heart valves. The invention includes a disposable patch having simple transducers and simple processing for monitoring heart valve performance via echo Doppler and processing the data to determine blood flow velocities and/or blood flow gradients.

Abstract: A device for 3-D imaging of the oral cavity for purposes of implant positioning, and in particular, a dental ultrasound scanner connected to a registration device that provides coordinates for realigning ultrasound images. The ultrasound scanner includes transducers having frequencies of 18 megahertz or higher and wavelengths of 80 microns or less. The reference device may be used as a surgical guide or a separate surgical guide may be created.

Abstract: A computer-implemented system for facilitating echocardiographic image analysis is disclosed. The system includes at least one processor configured to receive signals representing a first at least one echocardiographic image, associate the image with a first view category of a plurality of predetermined view categories, determine, based on the first at least one echocardiographic image and the first view category, a first quality assessment value representing a view category specific quality assessment of the first at least one echocardiographic image, and produce signals representing the first quality assessment value for causing the first quality assessment value to be associated with the first at least one echocardiographic image. The at least one processor may also be configured to do the above steps for a second at least one echocardiographic and a second view category that is different from the first view category image. Other systems, methods, and computer-readable media are also disclosed.

Abstract: A streak image enhancing unit subjects an ultrasound image representing a blood vessel to processing using a two-dimensional filter that is longer in the long axis direction of the blood vessel than in the short axis direction thereof so as to enhance a streak image corresponding to the long axis direction. A trace line candidate extracting unit extracts from the ultrasound image with the enhanced streak image a plurality of trace line candidates on the basis of the output values of the two-dimensional filter. A trace line selecting unit selects two trace lines corresponding to the inner boundary of the tunica intima and the boundary between the tunica media and the tunica externa of the blood vessel out of the plurality of trace line candidates on the basis of an evaluation value relating to continuity acquired for each trace candidate.

Abstract: Provided is an ultrasound diagnostic apparatus including a probe configured to induce displacement in tissue of an object by irradiating a first focused beam of a first frequency to the object; and a processor configured to obtain a first ultrasound image of the object in which displacement has been induced; to determine whether the induced displacement is appropriate based on the obtained first ultrasound image; when the induced displacement is not appropriate, to control the probe to irradiate a second focused beam of a second frequency different from the first frequency to the object, so as to induce displacement in the tissue of the object; and to process a second ultrasound image of the object in which displacement has been induced by the second focused beam.

Abstract: The present disclosure describes ultrasound imaging systems and methods that may be used to image, for example, breast tissue. An ultrasound imaging system according to one embodiment may include a probe, a sensor attached to the probe and operatively associated with a position tracking system, a processor configured to receive probe position data from the position tracking system. The user interface may be configured to provide instructions for placement of the probe at a plurality of anatomical landmarks of a selected breast of the subject and receive user input to record the spatial location of the probe at each of the plurality of anatomical landmarks. The processor may be configured to determine a scan area based on the spatial location of the probe at each of the plurality of anatomical landmarks and generate a scan pattern for the selected breast. The processor may be further configured to monitor movement of the probe.

Abstract: Ultrasound imaging devices, systems and methods are provided. In some embodiments, the ultrasound imaging devices include a flexible elongate member including a proximal portion and a distal portion, the distal portion configured to be positioned within a body of a patient, an ultrasound imaging element disposed at the distal portion of the flexible elongate member and configured to obtain imaging data from within the body of the patient; and a handle coupled to the proximal portion of the flexible elongate member. The handle includes an accelerometer configured to determine an orientation of the ultrasound imaging element.

Abstract: A system, method, and non-transitory computer-readable medium The system includes a processor configured to receive ultrasound data from an ultrasound reflected wave reflected from specimen features in an organic specimen resultant from an ultrasound incident wave transmitted into the organic specimen; to identify each region having data obtained from anatomic model data related to the organic specimen that satisfies selection criteria in comparison to the received ultrasound data; and to repeat consecutively, if the number of identified regions is not equal to one and the number of times the selection criteria are adjusted is less than a specified maximum number of adjustments, removal of identified status from each identified region, adjustment of the selection criteria in accordance with adjustment rules and identification of each region having data obtained from anatomic model data that satisfies the adjusted selection criteria in comparison to the received ultrasound data.

Abstract: Various embodiments of a breast ultrasound scanning apparatus are provided. In one embodiment, a system comprises an imaging assembly comprising an ultrasound transducer, a frame housing the imaging assembly, and a membrane directly and removably coupled to the frame. In this way, the cost of performing an ultrasound scan with the imaging assembly may be reduced while the comfort for a patient being scanned with the imaging assembly is increased.

Abstract: An ultrasound endoscope includes: an ultrasound transducer; a balloon groove in which a balloon band is fitted; a contact portion that constitutes a bottom surface of the balloon groove; a first wall portion that constitutes a proximal end side of the balloon groove and in which a first distance that is a distance from a center of a cross section orthogonal to an extension direction of the insertion portion to an outer circumference of the first wall portion is larger than a second distance that is a distance from the center of the cross section to the bottom surface; and a second wall portion that constitutes a distal end side of the balloon groove, in which a distance from the center of the cross section to an outer circumference of the second wall portion is larger than the second distance, and that includes a notch portion.

Abstract: A medical image transmitting method includes obtaining a medical image generated by imaging an object; performing a first determination to determine whether the object has an abnormality, based on the medical image; performing a second determination to determine, based on the first determination, whether to transmit at least one assistance image associated with the medical image; and when the object has no abnormalities, transmitting, to an external apparatus, the medical image, thereby minimizing a data processing amount and a data transmission amount.

Abstract: The invention provides novel targeted particles as contrast agents for use in molecular imaging of vulnerable plaque, and methods of preparation and application thereof.

Abstract: For viscoelastic estimation with ultrasound, shear wave speed is measured for different locations in a region of interest. For each location, the shear wave speed is estimated without frequency band division. A distribution of shear wave speeds in the region of interest is matched a modeled distribution corresponding to a particular value of the viscoelastic property.

Abstract: Systems and methods for estimating cardiac strain and displacement using ultrasound are disclosed. According to an aspect, a method includes receiving frames of images acquired from a subject over a period of time. The method also includes determining, in the frames of images, speckles of features of the subject. Further, the method includes tracking bulk movement of the speckles in the frame of images. The method also includes determining displacement of at least a portion of the subject based on the tracked bulk movement.

Abstract: An ultrasound diagnostic apparatus includes a transmitter, a receiver and a hardware processor. The transmitter outputs a drive signal for a C-mode image to an ultrasound probe. The receiver obtains a reception signal from the probe. The processor sets at least one mask in a frame of packet data of the reception signal; calculates a covariance matrix from a plurality of packet data included in the mask; calculates an eigenvector for the mask from the covariance matrix; calculates a first filter coefficient for the packet data by using the eigenvector and a gain matrix; performs interpolation on the first filter coefficient to calculate a second filter coefficient for packet data of each position in the frame; filters the packet data of the position by using the second filter coefficient; and generates C-mode image data from the filtered packet data.

Abstract: A monitoring system comprises an ultrasonic imaging, an electrocardiograph monitoring module, a data processing module, and an output module. The ultrasonic imaging module is used for obtaining an echocardiogram of heart; the data processing module serves to receive the echocardiogram and obtaining, according to the echocardiogram, mechanical motion identifiers of atriums and ventricles; the data processing module outputs in real-time the mechanical motion identifiers for atriums and ventricles, together with electrocardiogram information, to the output module in a comparative manner.

Abstract: The present invention provides an ultrasound imaging method, comprising: selecting an initial ultrasound image frame; marking a plurality of marking points on the initial ultrasound image frame; tracking updated positions of the marking points in subsequent ultrasound image frames; displaying updated marking points at the updated positions.

Abstract: Described herein are chargers for wirelessly charging an ultrasound imaging device. The charger may include a base member, a transmitter coil coupled to the base member, and a cradle extending from the top surface of the base member and including a surface configured to receive the ultrasound imaging device, where the first surface is disposed a vertical distance above the top surface of the base member. The cradle may be configured such that no portion of the ultrasound imaging device contacts the top surface of the base member when the cradle holds the ultrasound imaging device. The cradle may be configured to hold the ultrasound imaging device so as to substantially maintain alignment of a receiver coil of the ultrasound imaging device with the transmitter coil.

Abstract: The liquid sample capture apparatus captures a sample of a liquid and holds the sample for optical analysis. The apparatus may include a mount which is traversed by a sample conduit. The mount may have an elongated shape and two ferrules may be placed within the mount along the longitudinal axis of the mount. An end of each of the ferrules may extend into the sample conduit forming a narrowing of the sample conduit which holds the liquid and prevents it from escaping prior to analysis. The opposite ends of the ferrules may each be connected to an optical cable. The optical cables may be connected to an analytical device, for example, a spectrometer. The apparatus may be mounted within a toilet bowl where it may capture and analyze a urine sample.

Abstract: An apparatus includes a transfer adapter, a puncture member, a disinfection member, and a fluid reservoir. The transfer adapter has a proximal end portion and a distal end portion, and defines an inner volume configured to receive the puncture member. The transfer adapter is coupled to the disinfection member. The distal end portion of the transfer adapter includes a port fluidically coupled to the puncture member and configured to be placed in fluid communication with a bodily-fluid of a patient. The proximal end portion is configured to receive a portion of the fluid reservoir to allow the fluid reservoir to be moved within the inner volume between a first position, in which a surface of the fluid reservoir is placed in contact with the disinfection member, and a second position, in which the puncture member punctures the surface to place the puncture member in fluid communication with the fluid reservoir.

Abstract: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.

Abstract: A biopsy device includes a hollow needle, and a sample-receiving device that is movable in the hollow needle. A power-driven element having a motor is provided. A transport device is drivably coupled to the motor. The transport device includes a toothed flexible member drivably engaged with a drive gear. The toothed flexible member has a distal portion coupled to the sample-receiving device. The toothed flexible member is configured to move the sample-receiving device in the hollow needle between an extended position and a retracted position. The toothed flexible member has a proximal portion that extends proximal to the proximal end of the hollow needle. A housing element has a helical coiling-up groove configured to accommodate the proximal portion of the toothed flexible member when the sample-receiving device is retracted to the retracted position.