Abstract: Systems and methods for preparing a ligament graft construct for a ligament reconstruction or repair procedure are provided. In general, the described techniques utilize a reinforcement material having at least one suture tail extending therefrom. The reinforcement material is a ribbon or a ribbon-like flattened portion attached to or integrally formed with the at least one suture tail. To prepare a tissue repair construct, the reinforcement material is positioned on a first surface of a graft to extend from an end thereof and the at least one suture tail, coupled to a needle, is repeatedly passed through the reinforcement material and the surface of the graft to a second surface of the graft, and around a side portion of the graft to thereby create multiple suture loops. The tissue repair construct can be formed on each end of the graft.

Abstract: Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof.

Abstract: A device for the transplantation of a Descemet's membrane includes a longitudinal tube having an inner cavity, an inlet opening through which it is possible to introduce the Descemet's membrane into the device, and an outlet opening through which it is possible to eject the Descemet's membrane from the device, especially into the anterior eye chamber of a patient, wherein the device also includes, at least in the region of the outlet opening, a separation element which protrudes from the inner wall region of the tube into the cavity, especially a first separation element, the separation element dividing the cavity at least regionally, in particular dividing it in a region close to the separation element.

Abstract: An ophthalmic device includes an optic and a haptic structure coupled with the optic. The optic includes an optic axis. The haptic structure is coupled to the optic. The haptic structure retains the ophthalmic device within a capsular bag of a patient's eye. At least a portion of the haptic structure has a cross-section and a peripheral surface forming an outer periphery of a portion of the cross-section. At least a portion of the peripheral surface contacts the capsular bag and is smoothly curved.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: An intraocular lens (IOL) has a clear optic and means for actuating change in curvature in at least a portion the clear optic. The intraocular lens (IOL) can have anterior and posterior portions spaced apart by a cavity, and an actuator for urging change in curvature in at least one of said portions, with energy provided by an energy harvesting mechanism incorporated into haptics of said IOL.

Abstract: A Bernoulli gripper for ophthalmic lenses includes a gripper body with a first cavity corresponding in shape to an optic zone of an ophthalmic lens and a first channel formed within the gripper body. The first channel penetrates the first cavity at one end and includes a first port in the gripper body at another end of the first channel. The first channel is enabled to supply a fluid medium from the first port to the first cavity at a first velocity such that the ophthalmic lens positioned with the optic zone in proximity to the first cavity is subject to a first pressure force against the first cavity by the Bernoulli effect.

Abstract: Various medical devices are disclosed. In various embodiments, a system includes a heart valve and a device that functions to minimize a possibility for suture becoming entangled with a commissure post of the heart valve during an implantation procedure. In some examples, the device is a suture guard that includes one or more features that deflect suture to help minimize entanglement of the same with the commissure posts of the heart valve. In some examples, the features operate to deflect the commissure posts radially inwardly, while in other examples, the features overlay the commissure posts without deflecting that same.

Abstract: A device prepares leaflets for cardiovascular valve reconstruction from a pericardial tissue sheet harvested from a patient. A cutting tool is adapted to cut a predetermined pattern having a selected leaflet size. The device is continuously adjustable using a plurality of slidable blade segments forming a closed periphery. Radially-slidable links are slidably attached to respective blade segments. An adjustment disc is coupled to the links, wherein rotation of the adjustment disc varies a radial position of the links to modify an overlapping of the blade segments in order to select a corresponding size of the closed periphery.

Abstract: Thin, biocompatible, high-strength, composite materials are disclosed that are suitable for use in medical devices, such as a prosthetic valve for regulating blood flow direction. In one aspect, the leaflet material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a prosthetic heart valve leaflet. The leaflet material includes a coating of a non-elastomeric TFE-PMVE copolymer.

Abstract: Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having synthetic leaflets that are configured to promote and encourage tissue ingrowth thereon and/or therein. The leaflets are coupled to a leaflet frame to form a prosthetic valve suitable for use in biological anatomy.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a valved conduit. The valved conduit may include at least one leaflet and an interior surface that mitigates against thrombus formation within the conduit.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a prosthetic valve. The prosthetic valve may include a jacket configured to cover at least one of gaps, spaces, or interfaces in a frame or between one or more leaflets attached to the frame.

Abstract: Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having a leaflet frame and a leaflet construct including one or more leaflets. In some examples, the leaflet construct is coupled to the leaflet frame via a retention element. In some examples, the retention element is in the form of an outer frame that is coaxially arranged with the leaflet frame.

Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.

Abstract: Apparatus and methods are described herein for use in the transfemoral delivery and deployment of a prosthetic mitral valve. In some embodiments, a method includes inverting an outer frame of a prosthetic mitral valve when in a biased expanded configuration. After inverting the outer frame, the prosthetic mitral valve is inserted into a lumen of a delivery sheath such that the mitral valve is moved to a collapsed configuration. The delivery sheath is inserted into a femoral vein and moved through the femoral vein and a septum of a heart until a distal end of the delivery sheath is disposed in the left atrium of the heart. The prosthetic mitral valve is moved distally out of the delivery sheath such that the inverted outer frame reverts and the prosthetic mitral valve assumes its biased expanded configuration. The prosthetic mitral valve is then positioned within a mitral annulus of the heart.

Abstract: Various examples relate to a transcatheter delivery system including a sheath, a delivery catheter, and an implantable device (e.g., a prosthetic valve, a stent, a stent graft, occluder, or vascular filter) maintained in a collapsed configuration by the delivery catheter. The delivery catheter includes a plurality of fiber guides separated by one or more reduced profile sections each having a smaller transverse outer profile than the transverse outer profiles of the fiber guides.

Abstract: A dual member stent-valve for transcatheter delivery to a native heart valve needing replacement. A first component is attached to the native annulus upstream of the native leaflets maintaining native leaflet function, and is held to the native annulus by barbs that are activated by a torus balloon after the first component is fully expanded. The torus balloon can be implanted along with the support frame. A limiting cable restricts further expansion of the first component and holds a second component that contains the replacement leaflets.

Abstract: A method for improving the function of a valve in the heart of a patient, comprising attaching, to a leaflet of the valve, an element that is responsive to a magnetic field; positioning, outside of the heart of the patient, a coil connected to a source of electric energy; activating the source of electric energy to provide an oscillating current in the coil; and thereby providing an oscillating magnetic field through the coil to effect movement of the element and the leaflet.

Abstract: One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein said porous region exhibits a nano-textured surface.

Abstract: Methods and apparatuses for performing an orthopedic procedure in the sacroiliac region are disclosed. In one form, an aperture is formed that at least partially extends through at least one of an ilium and a sacrum. An undercutting system is inserted into the aperture. The undercutting system includes an insertion apparatus, a probe assembly and a cutting assembly. The probe assembly is moved with respect to the insertion apparatus from a retracted position to an extended position. The probe assembly is manipulated within a joint between the ilium and the sacrum while the probe assembly is in the extended position. The cutting assembly is moved with respect to the insertion apparatus from a retracted position to an extended position. The cutting assembly is manipulated within the joint between the ilium and the sacrum while the cutting assembly is in the extended position to form a fusion region.

Abstract: The present disclosure provides a hipbone prosthesis, comprising: a prosthesis main body (10), the prosthesis main body (10) being of an arched structure, the prosthesis main body including a first end portion (11) and a second end portion, and the first end portion (11) being contacted and matched with a sacrum (1); and an acetabular cup (20) and a connecting device (30), the acetabular cup (20) being connected with the second end portion in a position adjustable manner via the connecting device (30). According to the technical solutions of the present disclosure, the problems of unreliable supporting and easy fatigue break of a screw-rod system in the related technology are effectively solved.

Abstract: A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.

Abstract: Disclosed herein are patellar implants and methods to prepare bone for receiving the same. The patellar implant may include an articulating surface with an elliptically shaped median ridge. The anterior surface of the patellar implant may have a non-planar surface to engage with a resected natural patella. The non-planar surface may allow for varying thickness of the patellar implant. The patellar implant may include dual attachment features to secure patellar implant to a resected patella by onlay and inlay techniques. A method for attaching a patellar implant to a patella may include onlay and inlay techniques and may further include bone preparation at the implant-bone interface.

Abstract: A glenoid component in one embodiment includes a base component with a planar upper circular rim defining a first plane, a receptacle opening to the first plane, a lower planar circular surface defining a second plane parallel to the first plane, and a conical outer wall extending from the upper circular rim to the lower planar circular surface. The glenoid component includes an articulating component with an upper articulating surface and a lower coupling portion configured to be inserted into the receptacle.

Abstract: A glenosphere includes a body, a first surface, and a cavity defined with the body. The body defines a center and an engagement axis, the engagement axis spaced by an offset from the center. The first surface includes a first rim positioned radially outward from a second rim, a base surface portion, and a hood surface portion extending from the base surface portion and oriented at an obtuse angle relative to the base surface portion. The body defines a hood portion extending from the hood surface portion to a plane including the base surface portion. The cavity has a perimeter defined by the second rim, and includes a first cavity portion configured to receive an attachment structure attachable to a bone, and a second cavity portion configured to engage an engagement member of the attachment structure and oriented along the engagement axis.

Abstract: An intervertebral implant for being implanted between adjacent vertebrae is provided. The implant includes a generally elongate implant body having a length extending between opposite longitudinal ends thereof, a superior face and an inferior face. The superior face and inferior face include cortical teeth adjacent to the implant body longitudinal ends. Additionally, the superior and inferior faces include longitudinally central teeth intermediate the cortical teeth and have bone engaging ends. The central teeth have a sharper configuration than that of the cortical teeth bone engaging ends for biting into the softer central bone material of the vertebrae. The cortical teeth are arranged in a first density per unit area and the central teeth are arranged in a second density per unit area that is less than the first density.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first footplate includes a first surface oriented toward the first member, a second surface oriented away from the first member, and a sidewall extending between the first surface and the second surface. The first surface includes an alignment slot facing the first member. The alignment slot is open through the sidewall of the first footplate and configured to slidingly engage the first member to orient the first footplate relative to the first member.

Abstract: A vertebral body replacement device includes a first member and a first footplate detachably connectable to the first member, a second member and a second footplate detachably connectable to the second member, and a central member detachably connectable to the first member. The first member is axially displaceable relative to the second member in response to rotation of the central member relative to the first member to adjust the length of the vertebral body replacement device. The first member includes a pair of first fastener holes and a pair of second fastener holes angularly offset from the first fastener holes. The first footplate includes an aperture configured to align with one of the first fastener holes to orient the footplate in a first position or one of the second fastener holes to orient the footplate in a second position.

Abstract: The invention provides an impactor for transmitting an assembly force to a component of an orthopaedic implant. The impactor has first and second telescoping parts which are biased apart by means of a main spring. The main spring is compressed when an assembly force is applied to the parts. An indicator is latched against movement until it is released when the extent of the compression of the main spring by the application of an assembly force exceeds a threshold. The indicator then moves to provide the user with an indication that a minimum assembly force has been applied.

Abstract: Orthopedic devices are described including polymer compositions used to make the devices. The polymer composition contains a polyoxymethylene polymer in combination with various additives that prevent against agglomerations and spotting even when the composition contains significant amounts of coloring agents and/or waxes. In addition, the polymer composition has reduced formaldehyde emissions and excellent thermal stability properties.

Abstract: The present invention provides a method of manufacturing a customized breast prosthesis in such a manner as to perform three-dimensional scanning of user's body and apply the same shape, the same volume, and the same density as the actual breast to have the same weight, a system for manufacturing the same, a computer program and computer-readable record medium for the same, a customized breast prosthesis manufacture by the above method, and a customized correction brassiere for accommodating the customized breast prosthesis.

Abstract: A jointed mechanical device is provided. The device includes at least one element having a fixed end and a deflectable end. The device also includes at least one actuating structure having a first end coupled to at least the deflectable end of the element, where the actuating structure includes at least one elastic element in series with at least one non-elastic element. The device further includes at least one force actuator configured to apply an actuator force to a second end of the actuating structure. Additionally, the device includes a control system for adjusting an operation of the force actuator based at least one actuation input, an amount of the actuator force, and an amount of displacement generated by the force actuator.

Abstract: System, methods, and other embodiments described herein relate to a device for providing mobility assistance to a user. In one embodiment, a mobility system includes a support component including at least a waist device that is configured to secure the mobility system to the user at a waist area of the user. The mobility system includes a limb attached to the support component and extendable from the support component to a floor when the user is in a standing position. The limb is configured to support the user by providing a rigid structure between the floor and the user. The limb is configured to assist the user in transitioning from a seated position to the standing position by applying a substantially upward force to the user through the support component when transitioning to the standing position.

Abstract: A prosthetic foot includes a base spring, a top spring assembly, a connector assembly, and a heel cushion. The top spring assembly includes first and second spring members, and first and second bond connections. The second spring member extends parallel with and spaced apart from the first spring member. The first bond connection is between distal ends of the first and second spring members, and the second bond connection is between a distal end of the second spring member and a top surface of the base spring. The top spring assembly has a first portion arranged horizontally, and a second portion arranged vertically. The connector is connected to a proximal end of the top spring assembly to connect the prosthetic foot to a lower limb prosthesis. The heel cushion is mounted to the base spring at a location spaced forward of a heel end of the base spring.

Abstract: A prosthetic socket system includes a distal seal positionable between an interior surface of a prosthetic socket defining a pin bore and a distal end of a prosthetic liner carrying an attachment pin arranged to extend through the pin bore. The distal seal includes a base proximate to the attachment pin and defining an opening configured to receive and surround the attachment pin, a sealing portion extending distally from an outer radial portion of the base, and a variable clearance defined between the sealing portion and the base. The sealing portion is adapted to form a seal around the attachment pin and prevent fluid flow through the pin bore by deflecting relative to the base when the sealing portion engages the interior surface of the prosthetic socket.

Abstract: A prosthetic socket system includes a prosthetic lock assembly having a lock body defining a pin hole adapted to receive an attachment pin, and a locking device in the lock body. The locking device is engageable with the attachment pin to unidirectionally lock the attachment pin in the lock body while permitting insertion of the attachment pin in the lock body. A valve assembly is positioned in the lock body that is movable between a closed position and an open position in which the valve assembly is unsealed so that air moves into the lock body via the valve assembly. A release mechanism positioned in the lock body is arranged to both release the locking device from the attachment pin and move the valve assembly to the open position by translating the locking device in the lock body.

Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

Abstract: A bioabsorable stent is disclosed. The stent is made of a polymer and/or non-polymer material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.

Abstract: A braided stent system includes a stent body having a lumen formed by a plurality of braided members with interstices formed therebetween and a first expansion ring connected to the lumen of the stent body. The first expansion ring may include a frame defined by a plurality of interconnected support assemblies that are selectively positioned to impart an outwardly expanding radial force to the stent body, each support assembly can include a plurality of legs joined at a first intersection and connected to one of the other interconnected support assemblies at a second intersection opposite the first intersection. Each support assembly can include a claw portion mechanically connected to one or more of the interstices of the stent body so that the frame imparts an outward radial expansion force of the stent to facilitate use and delivery of the stent.

Abstract: An example medical device is disclosed. An example medical device includes an expandable stent. The stent includes a tubular scaffold formed of one or more interwoven filament. The tubular scaffold includes an inner surface and a flexible valve extending radially inward from the inner surface of the scaffold. Further, the valve is configured to shift between a closed configuration and an open configuration and the one or more filaments of the scaffold bias the valve to the closed configuration while in a nominally deployed state.

Abstract: All metal stent grafts and covered stents having either a single structural supporting stent member with concentrically positioned graft members on the luminal and abluminal surfaces of the stent member or a single graft member with concentrically positioned structural supporting stent members on the luminal and abluminal surfaces of the graft member are provided.

Abstract: A bidirectional twistable stent is disclosed. The stent comprises a cylinder-shaped stent body having a plurality of axially arranged rows of struts encircling a central lumen and a plurality of flex connectors that connect at least two adjacent rows of struts in such a manner that allows the stent to be twisted clockwise or counter clockwise without causing deformation of any struts in the stent body. Also disclosed are the method of making the stent, method of using the stent, and a kit containing the stent.

Abstract: A method and assembly are provided for securing a stent within a vessel of a subject. The method includes moving the stent to a position along the vessel and inflating a balloon positioned on a downstream side of the stent. The method further includes deploying the stent at the position and verifying that the deployed stent does not float from the position in a downstream direction relative to the inflated balloon. The method further includes deflating the balloon. The assembly includes the stent, a plurality of channels internal to the stent and a deployment mechanism configured to deploy the stent when the stent is positioned in the vessel of the subject. In another embodiment, a system is provided that includes the assembly, a guide wire, a balloon lumen, an inlet port to inject fluid into the balloon lumen and a handle operatively coupled to the deployment mechanism.

Abstract: A prosthesis for attachment in a passage surrounded by tissue, which includes a tubular element with a proximal and distal flange which extend around the tubular element. The distal and proximal flange have a radial position, in which they project in a radially outward direction in order to clamp tissue surrounding the passage between the distal and proximal flange. The distal flange and proximal flange consist of distal flange feet respectively proximal flange feet. The distal and proximal flange feet are bendable from the radial position, against a pre-tension created by the memory material, to an extended position, in which the distal and proximal flange feet extend in the longitudinal direction of the tubular element and are fixable in this extended position, in order to return to the radial position under the influence of the pre-tension once the fixing has been undone.

Abstract: A vascular stent conveying system includes a housing, an outer cannula, a cleaning tube, an inner cannula, and a driving assembly. The outer cannula is located outside the housing and is connected to a first end of the housing. The cleaning tube is connected to a second end of the housing, a first end of the cleaning tube is located in the housing, and a second end of the cleaning tube extends out of the housing. A part of the inner cannula is located in the housing, a first end of the inner cannula extends into the outer cannula, and a second end of the inner cannula extends from the first end of the cleaning tube to a tube chamber of the cleaning tube. A part of the driving assembly is located in the housing, and operably engaged with a part of the inner cannula located in the housing.

Abstract: Various embodiments are described for a stent delivery device that utilizes a push button using a slot and pin on a shuttle with a rack for slow retraction of the outer sheath as well as a flanged member connected to the outer sheath for fast retraction of the outer sheath during delivery of a self-expanding implantable device such as a stent or stent graft.

Abstract: A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. The catheter shaft may include an inner member having a distal region and a deployment sheath disposed about the inner member. A stent may be disposed between along the distal region of the inner member. A handle may be coupled to the catheter shaft. An actuation mechanism may be coupled to the handle for proximally retracting the deployment sheath. The actuation mechanism may be designed to shift relative to the handle from a pre-deployment position, along an early deployment region, and along a full deployment region. The medical device may also include a force reduction member for applying a force to the actuation mechanism while the actuation mechanism is disposed along the early deployment region.

Abstract: A device for treating obesity by limiting absorption of food through a wall of a duodenum of a patient including a sleeve inserted into the duodenum of a patient. The sleeve includes a plurality of first blocking areas and a plurality of first food absorption areas, the first blocking areas providing duodenum wall covers to prevent food absorption through the duodenum wall and the first blocking areas together defining a first total blocking area. The first food absorption areas providing access to the duodenum wall to enable food absorption through the duodenum wall and the first food absorption areas together defining a first total absorption area.