Abstract: An apparatus and method for reprocessing a medical device includes a decontamination basin, a first flush conduit, a second flush conduit, and a manifold. The first and second flush conduits have respective first and second coupling ports configured to fluidly connect to the medical device positioned within the decontamination basin. The manifold is fluidly connected to the first and second flush conduits and configured to distribute the fluid received therein accordingly. The apparatus also includes a first valve, a second valve, and a primary pump configured to discharge the fluid into the manifold at a predetermined supply flow rate. The first and second valve are positioned respectively in the first and second flush conduits for balancing the respective flow rates discharged therefrom at a first predetermined conduit flow rate and a second predetermined conduit flow rate.

Abstract: An endoscope reprocessor includes: a treatment tank in which an endoscope is arranged; a drainage conduit including a liquid lead-out port opened in a bottom surface of the treatment tank; an on-off valve arranged in an intermediate position of the drainage conduit; a circulation conduit including a circulation port, the circulation port being opened between the on-off valve and the liquid lead-out port of the drainage conduit and in a position closer to a ground than the liquid lead-out port, the circulation conduit introducing liquid introduced from the circulation port to the treatment tank; a filter arranged in the drainage conduit and covering the circulation port; and a holding portion arranged in the filter or the drainage conduit, the holding portion holding the filter at a position at which the circulation port is covered.

Abstract: A cover (1) for a shaft of a medical scoping device comprises tubular member (2) arranged for application on the distal tip of the medical scoping device. The cover (1) comprises a plurality of projecting elements (3) spaced apart circumferentially around the tubular member (2), each projecting element having a base portion (13) and an arm portion (14). The projecting elements are pivotably mounted on the tubular member about a pivot axis. The base portion (13) comprises a detent (20), and the tubular member comprises a contact region, for example a protuberance (23), said contact region being located such that pivoting movement of the projecting element for moving the arm portion in a distal direction can effect impacting of the detent (20) on the contact region (23).

Abstract: An ophthalmic method and apparatus for noninvasive diagnosis and quantitative assessment of cataract development and/or color blindness is provided. The method and apparatus with direct feedback from the subject, or historical data, provides a quantitative method for noninvasive diagnosis and quantitative assessment of cataract development.

Abstract: A handheld smart phone includes programming for performing various vision-related tests. The smart phone includes a touch sensitive screen, microphone, speaker, other sensors, processor and persistent storage for execution of software, multiple communications network interfaces and other device interfaces. The display delivers vision tests and, together with the speaker, related audio instructions to a user. The user interacts with the vision tests by using tactile and audio commands to the device screen and microphone. The test results are assembled into a report that can be transmitted to persons of the user's choice, such as a care provider. The capability is included for transmitting results to the remainder of the system for storage, analysis, events, alerts for medical personnel's user treatment and multiple user population analysis.

Abstract: A process for assessing at least one characteristic of a user's vision includes determining a characteristic of at least one camera of a mobile device; using the at least one camera, capturing at least one image of an object; determining, with reference to a portion of the at least one image composed of the object, a distance from the mobile device to the object at a time of capture of the at least one image; and receiving input from the user in response to material presented on the object.

Abstract: A thin film analysis apparatus and method for a curved surface is disclosed. The apparatus includes an illuminator, a sample, an imaging group, one or more beamsplitters, optional focusing groups, polarization analyzers, detectors and optional display and analysis systems. The image series are recorded, preferably substantially synchronously. The system can be calibrated by as few as one reference phantom that has the same or substantially similar geometry as the sample under test. Based on calibration, a lookup table of the effective reflectance can be created, which is proportional to the portion of the light that reaches the detectors, or the mutual subtraction of the effective reflectance values of all possible combinations of the unknown optical parameters within certain search ranges of the sample. The experimentally measured results are compared with the lookup table, and optical properties, for example, the thicknesses and refractive indices of the thin film can be determined.

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

Abstract: There are included an acquiring unit configured to acquire a parameter regarding capturing of a first tomographic image of an eye to be examined, an acquiring unit configured to acquire a parameter regarding capturing of a second tomographic image of the eye to be examined, wherein capturing of the second tomographic image is being performed after capturing of the first tomographic image, and a warning unit configured to issue a warning against capturing of the second tomographic image in accordance with a comparison between the parameter regarding capturing of the first tomographic image and the parameter regarding capturing of the second tomographic image.

Abstract: The present disclosure relates to an ophthalmic surgical microscope including a magnifying lens positioned in an optical path, a reflection inverter positioned in the optical path, and an ocular lens or eyepiece positioned in the optical path. The reflection inverter may include A Schmidt-Pechan prism or a pair of inverting lenses and a reduction lens.

Abstract: A lens-sensor array for imaging parts of an eye comprises a lens array disposed onto a sensor array. The lens array transmits a light from a lens towards the sensor array. The lens array comprises a first section configured to direct the light reflected by a first part of the eye to the sensor array, and a second section configured to direct the light reflected by a second part of the eye to the sensor array. The first section comprises first sub-sections, each first sub-section comprising at least one first lenslet. The second section comprises second sub-sections, each second sub-section comprising at least one second lenslet. The sensor array comprises sensors that detect the light from the lens array and generate sensor signals corresponding to the light reflected by the first part of the eye and the light reflected by the second part of the eye.

Abstract: An optical measurement system: passes a probe light beam through a variable focal length lens to the retina of an eye, and returns light from the retina through the variable focal length lens to a wavefront sensor; adjusts the focal length of the variable focal length lens to provide a desired characteristic to at least one of: the probe light beam, and the light returned by the retina to the wavefront sensor; passes a calibration light through the variable focal length lens to the wavefront sensor while the variable focal length lens is at the adjusted focal length to ascertain the adjusted focal length; and makes a wavefront measurement of the eye from the light returned from the retina of the eye through the variable focal length lens to the wavefront sensor, and from the adjusted focal length ascertained from the calibration light received by the wavefront sensor.

Abstract: A handheld device measures all vital signs and some hemodynamic parameters from the human body and transmits measured information wirelessly to a web-based system, where the information can be analyzed by a clinician to help diagnose a patient. The system utilizes our discovery that bio-impedance signals used to determine vital signs and hemodynamic parameters can be measured over a conduction pathway extending from the patient's wrist to a location on their thoracic cavity, e.g. their chest or navel. The device's form factor can include re-usable electrode materials to reduce costs. Measurements made by the handheld device, which use the belly button as a ‘fiducial’ marker, facilitate consistent, daily measurements, thereby reducing positioning errors that reduce accuracy of standard impedance measurements. In this and other ways, the handheld device provides an effective tool for characterizing patients with chronic diseases, such as heart failure, renal disease, and hypertension.

Abstract: A biosensor assembly that measures multiple physical parameters is disclosed. The biosensor assembly includes a first implantable probe and a first skin contacting electrode. Wherein a first physiological parameter is measured between the first implantable probe and the first skin contactable electrode.

Abstract: An eye-examining apparatus in which a visible light optical system for observing a shape of an examinee's eye and an infrared optical system for detecting a shape of the cornea of the examinee's eye are integrated. The eye-examining apparatus having an integrated optical system comprises: an infrared light source for irradiating a cornea of the examinee's eye with infrared light; a visible light source for irradiating the eye with visible light; an image detector both for detecting an image of the infrared light which is irradiated from the infrared light source and reflected from the cornea of the eye and for detecting an image of the visible light which is irradiated from the visible light source to the eye; and a visible light blocking filter inserted in an optical path of the visible light and the infrared light traveling toward the image detector for blocking the visible light.

Abstract: A configuration is provided for firmly fixing a transmitting and receiving unit for IVUS and a transmitting and receiving unit for OCT in a probe of an imaging apparatus for diagnosis in which space saving is achieved. The probe includes a cylindrical housing in which an ultrasonic wave transmitting and receiving unit is arranged on a distal side and a light transmitting and receiving unit is arranged on a proximal side. The ultrasonic wave transmitting and receiving unit and the light transmitting and receiving unit being fixed to the cylindrical housing in a state where a base of the ultrasonic wave transmitting and receiving unit and a base portion of the ball lens of the light transmitting and receiving unit are embedded in an adhesive agent.

Abstract: An MRI apparatus includes an image processor configured to generate a scout image based on an MR signal that is obtained from an object; a display configured to display slices, which respectively correspond to portions of the object, on the scout image; and an input interface configured to receive a first user input selecting at least one slice among the slices displayed in the scout image. The first user input corresponds to a user command to change a displaying property of the at least one slice to be displayed distinguishably from non-selected slices in the scout image and the display displays the slices on the scout image so that the at least one slice is displayed differently from the non-selected slices.

Abstract: Described herein are systems and methods for noninvasive functional brain imaging using low-coherence interferometry (e.g., for the purpose of creating a brain computer interface with higher spatiotemporal resolution). One variation of a system and method comprises optical interference components and techniques using a lock-in camera. The system comprises a light source and a processor configured to rapidly phase-shift the reference light beam across a pre-selected set of phase shifts or offsets, to store a set of interference patterns associated with each of these pre-selected phase shifts, and to process these stored interference patterns to compute an estimate of the number of photons traveling between a light source and the lock-in camera detector for which the path length falls within a user-defined path length range.

Abstract: Methods, systems, and computer readable media for taking measurements of a material, including determining material anisotropy, are provided. According to one aspect, a method for determining tissue anisotropy comprises: applying, to a tissue sample, a first force having a direction and having a coronal plane normal to the direction of the force, the first force having an oval or other profile with long and short axes within the coronal plane, the long axis being oriented in a first direction within the coronal plane, and measuring a first displacement of the tissue; applying, to the tissue sample, a second force, and measuring a second displacement of the tissue; and calculating a tissue elasticity anisotropy based on the measured first and second displacements. Furthermore, by applying the first and second forces multiple times, tissue viscosity, elasticity, or other anisotropy may be calculated from the multiple displacement measurements.

Abstract: A 3D scanner system for detecting and/or visualizing cariogenic regions in teeth based on fluorescence emitted from said teeth, the 3D scanner system including data processing means configured for mapping a representation of fluorescence emitted from the teeth onto the corresponding portion of a digital 3D representation of the teeth to provide a combined digital 3D representation.

Abstract: A smart phone or tablet includes laser diodes, at least some of which may be pulsed and generate near-infrared light and include Bragg reflectors to direct light to tissue/skin. An array of laser diodes generates near-infrared light and has an assembly in front of the array that forms the light into a plurality of spots on the tissue/skin. A receiver includes detectors that receive light reflected from the tissue/skin. An infrared camera receives light reflected from the tissue/skin and generates data based on the received light. The smart phone or tablet is configured to generate a two-dimensional or three-dimensional image using at least part of the data from the infrared camera.

Abstract: A photoacoustic apparatus is the photoacoustic apparatus that receives an acoustic wave, which is generated from an object irradiated with light, at a plurality of relative positions with respect to the object using a conversion element, and acquires a photoacoustic image representing information on the object, the photoacoustic apparatus including: an imaging unit configured to acquire an optical image of the object; and a positional alignment unit configured to align positions of the photoacoustic image and the optical image based on positional relationship information, which is information representing a positional relationship between a first coordinate system in the optical image and a second coordinate system in the photoacoustic image.

Abstract: An optical scanning device includes: an optical scanning unit configured to repeatedly scan an irradiation destination of irradiation light to a predetermined trajectory; a light emission control unit configured to control light emission of the irradiation light to irradiate irradiation points to the predetermined trajectory; and a driving signal generation unit configured to generate a driving signal for driving the optical scanning unit, wherein the light emission control unit irradiates the irradiation points to the predetermined trajectory so that the irradiation points are substantially uniformly dispersed in a region in which a density of the irradiation points is relatively low in a region in which the irradiation light is irradiated.

Abstract: Employed is an information acquisition apparatus which acquires characteristic information about an object using a reception signal of acoustic waves generated by the object that is irradiated with light, the apparatus having: region acquisition unit for acquiring information indicating a plurality of regions of mutually different characteristics, in the object; sound velocity determination unit for determining sound velocity in the plurality of regions, using the information indicating the plurality of regions; and characteristic information acquisition unit for acquiring the characteristic information about the object, using the sound velocity and the reception signal.

Abstract: A measurement system (1) for characterizing sample tissue (4; 4a, 4b) in a non-invasive way comprises a stimulation device (3; 3a, 3b; 3a, 3c) for thermal stimulation of the sample tissue (4; 4a, 4b), a temperature sensor (2; 2a, 2b) for capturing at least one temperature profile of the sample tissue (4) and a computing unit (11) connected to the temperature sensor (2; 2a, 2b) for processing data delivered by the temperature sensor (2; 2a, 2b). Thermal radiation radiated by the sample tissue (4; 4a, 4b) from at least a measurement area (5) is detectable as a result of the thermal stimulation by the temperature sensor (2; 2a, 2b) during the thermal stimulation of the sample tissue (4; 4a, 4b). The stimulation device comprises a temperature regulating body (3; 3a, 3b; 3a, 3c) which is in continuous contact with the sample tissue (4; 4a, 4b) in a contact area (6) during an entire measurement period.

Abstract: The present invention relates generally to a non-invasive device for monitoring blood pressure using principle of applanation tonometry. A novel device for measuring pressure pulse comprises a differential screw mechanism, a sensor module connected to the screw mechanism, and an overall enclosure housing the sensor module and the differential screw mechanism in one unit. A pair of straps is attached to the enclosure, wherein said straps as a flex lock brace through a hinge to change the angle of extension of the wrist as required. The multi component sensor module comprises of a snap-fit enclosure, which houses a tactile-based force sensitive resistor, and a mechanism to transmit the forces from the artery. The force transmission mechanism comprises of a gel layer and a gel head. The differential screw mechanism ensures precise hold down pressure in multiple stages via screwing and unscrewing steps to accurately measure the blood pressure.

Abstract: A system for estimating breathing frequency and heartbeat frequency of a subject, comprises at least one ultra-wideband (UWB) transceiver, connected to at least one hardware processor, configured to: receive a plurality of readings from the UWB transceiver, each of the readings having a time and comprising a plurality of intensity values at the time, each of the intensity values having a corresponding distance value representing a distance between the UWB transceiver and the subject; determine a Range-Doppler map from the plurality of readings; analyze the Range-Doppler map to determine a breathing frequency value of the subject; perform null steering of a plurality of Doppler-map frequencies in the Range-Doppler map to nullify the breathing frequency value and integer multiples of the breathing frequency value to obtain a plurality of combined frequencies; and determine a heartbeat frequency value for which a plurality of computed frequencies corresponds with the plurality of combined frequencies.

Abstract: Apparatus for monitoring a clinical condition of a subject is described. A motion sensor senses motion of the subject without contacting or viewing the subject, and generates a sensed motion signal responsive to the sensed motion. A signal analyzer is adapted to analyze the motion signal to identify a cough in the subject. Other applications are also described.

Abstract: Disclosed herein are devices, systems, and methods for monitoring blood pressure in the inferior vena cava (IVC) to diagnose acute decompensated heart failure (ADHF). An underlying principle of the disclosed systems and methods is that it is possible to reduce or prevent hospitalization by monitoring blood pressure in the IVC because an increase in IVC pressure is correlated with worsening renal function, causing fluid overload. Accordingly, the disclosed systems and methods monitor renal function by monitoring IVC pressure to detect early signs of ADHF by identifying increases in pressure over time. To monitor pressure in the IVC, a pressure sensor can be implanted in the IVC and can wirelessly transmit sensor data to a monitor device worn by the subject. If a pressure trend exceeds a specified threshold, the monitor device can generate an alert.

Abstract: Pressure sensing guidewire assemblies are described herein where the guidewire assembly may be comprised of an elongate guidewire body and multiple pressure sensors secured near or at a distal end of the guidewire body. The signals obtained from the guidewire connectors and aortic sensor modules may be synchronized to minimize signal acquisition delays. The signals may be further processed to equalize the pressure waveforms by shifting the connector waveform to align correctly with the aortic module waveform and improve output signals.

Abstract: A connector (140) is provided with a holding component (141), a support component (148), a terminal (144) electrically connected to a contact of a guide wire (130) held by the holding component (141), and a guide component (147) rotatable around an axial line (130A) of the guide wire (130) with respect to the support component (148). The holding component (141) is provided with a body (150) having an insertion hole (150a) for the guide wire (130) and a holding piece (151) extending along an axial line of the insertion hole (150a) from the body (150) and capable of being elastically deformed inward in a radial direction with respect to the axial line. The guide component (147) has a guide surface (165a) guiding the holding piece (151) inward in the radial direction. The holding component (141) is slid along the axis line of the insertion hole (150a) with respect to the guide component (147), whereby the holding piece abuts on the guide surface (165a) to be elastically deformed inward in the radial direction.

Abstract: The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.

Abstract: There is provided an information processing apparatus, an information processing method, and a program capable of obtaining accurate blood flow information while suppressing power consumption. The information processing apparatus includes: an estimation unit configured to estimate another kind of blood flow information associated with one kind of blood flow information from the one kind of blood flow information obtained through blood flow measurement on the basis of relation information indicating a relation between the two different kinds of blood flow information.

Abstract: The present disclosure generally relates to a portable vital monitoring system and a method for monitoring an individual's vitals using a portable vital monitoring system. The portable vital monitoring system includes a stand-alone portable vital monitoring device that allows the individual to detect or measure the individual's vitals. The stand-alone device includes a plurality of sensing devices for detecting data indicative of the individual's vitals and generating one or more signals indicative of the vital data. The system also includes a control unit connected to the sensing devices for processing the signal such that the data can be displayed to and understood by the individual. The system also includes a vital monitoring application in wireless communication with the vital monitoring device via a wireless communication module.

Abstract: Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm.

Abstract: Provided is a device and method for diagnosing a blood circulation disturbance. The device includes a measurement unit configured to measure a first signal and a second signal associated with a cardiac impulse of a patient at two different points in a body of the patient, a matching unit configured to match cycles of the first signal and the second signal, and a diagnosis unit configured to acquire reference points included in the matched cycles of the first signal and the second signal and to diagnose the blood circulation disturbance of the patient using a time difference between the reference points.

Abstract: Devices, systems, and methods for filtering medical device noise artifacts from circulatory waveform signals are disclosed. A circulatory pressure is measured and transformed from the time domain to the frequency domain for analysis to determine patient status. To avoid artifacts of the pumping, the time-domain measurements are filtered to generate a filtered time-domain signal, by removing active pumping periods. The filtered time-domain signal is transformed into a frequency-domain signal, which is analyzed based upon peaks indicating respiratory rate, heart rate, or harmonics thereof. Peaks may be adjusted based on a ratio that considers removed signals. A metric of patient status is then determined from the peaks or corresponding frequencies. The patient status may be related to blood volume of the patient and may be used to control pump operation.

Abstract: Systems and methods are provided for operating a physiological monitoring system that comprises a distributed algorithm. The physiological monitoring system ma comprise a sensor and a physiological monitor that may be communicatively coupled with the sensor. The sensor may store a first executable code segment and the physiological monitor may store a second executable code segment. The physiological monitor may be configured to receive the first executable code segment and execute the first and second executable code segments to determine at least one physiological parameter of a subject based on physiological signal provided by the sensor. The physiological monitor may be configured to delete or deactivate the first executable code segment. The physiological monitor may also store a configurable algorithm stage that may be configured based on algorithm configuration data received from the sensor.

Abstract: An optical proximity sensor assembly includes an optical proximity sensor with an IR LED emitting light having an infrared wavelength, an IR photo detector sensitive to the infrared wavelength, an optical barrier blocking direct light rays from the LED to the IR photo detector and permitting reflected light rays to reach the at least one photo detector; and an electronic integrated circuit with an amplifier for amplifying a signal detected by the photo detector, an analog to digital converter, LED drivers, noise reduction and ambient light cancellation circuitry, and a digital interface for communication with a microcontroller. The optical proximity sensor is accommodated on a wearable carrier. A single sensor may include a plurality of identical or different LEDs, a plurality of photodiodes, or both. Also, several sensors may be placed on a person's skin along a vascular path to obtain data relating to blood flow and artery stiffness.

Abstract: A capacitive accelerometer device is provided, and includes a capacitive accelerometer module, a display device and a signal line. The capacitive accelerometer module includes one or more capacitive accelerometers for sensing an arterial acceleration pulse wave of a user. The display device includes a displayer and a speaker. The displayer is used to display the arterial acceleration pulse wave of the user. The speaker emits an audible signal according to a change value of the arterial acceleration pulse wave. The display device electrically connects to the capacitive accelerometer module via the signal line. The display device automatically senses the arterial acceleration pulse wave of the user and correspondingly generates the change value. The display device generates a prompt signal when the change value is equal to or larger than a predetermined value.

Abstract: Mechanisms are provided to implement an automated echocardiograph measurement extraction system. The automated echocardiograph measurement extraction system receives medical imaging data comprising one or more medical images and inputs the one or more medical images into a deep learning network. The deep learning network automatically processes the one or more medical images to generate an extracted echocardiograph measurement vector output comprising one or more values for echocardiograph measurements extracted from the one or more medical images. The deep learning network outputs the extracted echocardiograph measurement vector output to a medical image viewer.

Abstract: Electroanatomic mapping of the epicardium includes acquiring first and second electroanatomic data from first and second epicardial locations, acquiring a closed 3-dimensional image of the epicardium and modeling the image as a 3-dimensional triangular mesh. The first and second locations align with front-facing triangles and rear-facing triangles of the mesh. The second locations are projected from the rear-facing triangles onto the closest front-facing triangles. The first and second electroanatomic data are displayed on the front-facing triangles and the closest front-facing triangles, respectively.

Abstract: The present disclosure provides systems and methods for generating an electrophysiological map of a geometric structure. The system includes a computer-based model construction system configured to acquire electrical information at a plurality of diagnostic landmark points, assign a color value, based on the acquired electrical information, to each of the diagnostic landmark points, create a first 3D texture region storing floats for a weighted physiological metric, create a second 3D texture region storing floats for a total weight, for each diagnostic landmark point, additively blend the color value of the diagnostic landmark point into voxels of the first 3D texture region that are within a predetermined distance, normalize the colored voxels using the second 3D texture region to generate a normalized 3D texture map, generate the electrophysiological map from the normalized 3D texture map and a surface of the geometric structure, and display the generated electrophysiological map.

Abstract: We disclose a portable wearable device for measuring electrocardiographic signals, the device comprising a first portion comprising at least two electrodes; a second portion comprising at least three electrodes; the first portion and the second portion being vertically spaced from one another; a controller configured to take: a first potential difference measurement using one of the electrodes of the first portion and one of the electrodes of the second portion; a second potential difference measurement using one other of the electrodes of the first portion and one other of the electrodes of the second portion; and a third potential difference measurement using one other of the electrodes of the first portion and one other of the electrodes of the second portion. The controller is configured to simultaneously take the first, second and third potential difference measurements at three independent positions of a user's body.

Abstract: Systems, methods, and interfaces are described herein for assisting a user in noninvasive evaluation of patients for cardiac therapy and noninvasive evaluation of cardiac therapy being delivered. The systems, methods, and interfaces may provide graphical representations of cardiac electrical activation times about one or more portions of human anatomy and one or more cardiac health metrics.

Abstract: Systems and methods of processing raw electrocardiogram (ECG) waveform data of a patient into estimated real-time ECG waveform data. The method includes sensing at least one physical non-cardiac influence on the raw ECG waveform data, constructing a time domain computer model of the at least one physical, non-cardiac influence on the raw ECG waveform data, and adaptively filtering the raw ECG waveform data in the time domain using the constructed time domain computer model of the at least one physical non-cardiac influence on the raw ECG waveform data to form the estimated real-time ECG waveform data. The system can include an ECG device for collecting raw ECG waveform data, at least two ECG electrodes positioned on the patient and electrically coupled to the ECG device, and a processor coupled to the ECG device and configured to compute a time domain model of an artifact created by chest compressions.

Abstract: Disclosed are various examples and embodiments of a multiple configuration electrophysiological (EP) mapping catheter, and systems, devices, components and methods associated therewith. In some embodiments, the catheter is capable of being controllably deployed by a user inside or near a patient's heart in different geometric configurations according to the particular EP sensing and ablation requirements and needs at hand. For example, in some embodiments one and the same EP mapping catheter can be used to sense localized electrical signals originating in or near a patient's pulmonary vein or artery, and also to sense high-or-medium-spatial resolution electrical signals in the patient's atrium.

Abstract: An elongate medical device may comprise an elongate tubular body, an electrode, and a trace. The elongate tubular body may comprise a distal end portion and a proximal end portion, the body defining a longitudinal axis. The electrode may comprise electrically-conductive ink extending circumferentially about a portion of the distal end portion. The trace may comprise electrically-conductive ink, electrically coupled with the electrode, extending proximally from the electrode.

Abstract: In situations in which an implantable medical device (e.g., a subcutaneous ICD) is co-implanted with a leadless pacing device (LPD), it may be important that the subcutaneous ICD knows when the LPD is delivering pacing, such as anti-tachycardia pacing (ATP). Techniques are described herein for detecting, with the ICD and based on the sensed electrical signal, pacing pulses and adjusting operation to account for the detected pulses, e.g., blanking the sensed electrical signal or modifying a tachyarrhythmia detection algorithm. In one example, the ICD includes a first pace pulse detector configured to obtain a sensed electrical signal and analyze the sensed electrical signal to detect a first type of pulses having a first set of characteristics and a second pace pulse detector configured to obtain the sensed electrical signal and analyze the sensed electrical signal to detect a second type of pulses having a second set of characteristics.

Abstract: The invention refers to an apparatus that determines the abnormal electrical potential points which appear in the ventricular myocardium, particularly the left ventricle, which are capable of generating arrhythmias with a serious impact. The apparatus may assist the physician in objectively identifying, in real time, of the points which require ablating. The apparatus to determine the points of abnormal electrical potential from the ventricular myocardium contains an amplification and analogue filtering module, an analogue to digital signal converter, a hardware device which contains a microchip for digital processing, by means of a software, of signals received from an EKG and a catheter, with a display for the visualization of the signals received from the EKG and the catheter, as well as the abnormal electrical potentials found in the ventricular myocardium, identified via the software.