Abstract: A stimulating section applies stimulation to a living body. A first lead electrode and a second lead electrode are attached on the living body. A first amplifier circuit amplifies potential difference that is evoked between the first lead electrode and the second lead electrode due to the stimulation. A first switch cancels electrical connection between the first amplifier circuit and each of the first lead electrode and the second lead electrode at least while the stimulation is applied. A high-pass filter includes a capacitor (C) and filters a frequency component of an output from the first amplifier circuit that is no less than a predetermined value. A second amplifier circuit amplifies the output from the first amplifier circuit. A second switch stops charging/discharging of the capacitor (C) and decreases a gain of the second amplifier circuit at least while the first switch cancels the electrical connection.

Abstract: Devices and methods are disclosed that detect and/or prevent intraoperative full thickness penetration of anatomic walls and provide delineation of anatomic structures during surgery.

Abstract: The present disclosure is directed to a system and method for measuring impedance across a plurality of electrodes and assessing proximity or contact between electrodes of a medical device and patient tissue. In one embodiment, contact is assessed individual electrodes and cardiac tissue using bipolar electrode complex impedance measurements. Initially, baseline impedance values are established for each of the individual electrodes based on the responses of the electrodes to the applied drive signals. After establishing the baseline impedance values a series of subsequent impedance values are measured for each electrode. For each electrode, each subsequent impedance value may be compared to a previous baseline impedance value for that electrode. If a subsequent impedance value is less than the baseline impedance value for a given electrode, the baseline impedance value may be reset to the subsequent impedance value.

Abstract: Embodiments can relate to a system configured for locating and tracking the movement of a medical device (e.g., a catheter). Embodiments of the system can include use of energized induction coil assemblies located outside of a patient to generate an electronic field and/or a magnetic field to induce signals in an inductive sensor located in the tip of the catheter and/or stylet. The sensor signals can be analyzed to provide data related to the position and trajectory of the catheter tip and/or stylet as it is moved within the body. In some embodiments, the energized induction coil assemblies can be disposed in and/or on a platform that is placed on a patient's chest.

Abstract: A capsule adapted to be introduced into the digestive system and gastrointestinal (Gl) tract of a mammal which consists of a capsule shaped container consisting of a wall material capable of being bio compatible with the digestive system and being adapted to protect the electronic and sensor devices contained in the capsule. The capsule contains gas composition sensors operable at several temperature points for a short duration, a temperature sensor, a micro controller, a power source and a wireless transmission device. The capsule wall incorporates gas permeable membranes adjacent said gas sensors. The microprocessor is programmed to receive data signals from the sensors and convert the signals into gas composition and concentration data and temperature data suitable for transmission to an external computing device.

Abstract: A medical system for testing air leaks in tissue includes a housing unit, a tubular member, a source of negative pressure, a source of positive pressure, and a pressure gauge. The housing unit defines an interior chamber configured for receipt of at least a portion of an organ. The tubular member is coupled to the housing unit and includes a first end portion configured to be coupled to the portion of the organ. The source of negative pressure is configured to be in fluid communication with the interior chamber of the housing unit. The source of positive pressure is configured to be in fluid communication with the portion of the organ via attachment to a second end portion of the tubular member. The pressure gauge is in communication with the interior chamber of the housing unit and the tubular member to determine a pressure differential therebetween.

Abstract: There is provided a respiratory waveform drawing system. The system includes load detectors; a center of gravity position calculation unit; an oscillation coordinate setting unit configured to perform: obtaining a first extreme point at which a distance between an initial origin and the position of the center of gravity of the subject is maximized; obtaining a second extreme point which appears at an opposite side of the initial origin from the first extreme point, and at which a distance between the initial origin and the position of the center of gravity of the subject is maximized; setting a direction connecting the first and second extreme points as a direction of a tentative oscillation axis; and setting a midpoint between the first and second extreme points as a tentative oscillation origin; and a waveform drawing unit configured to draw the respiratory waveform.

Abstract: Methods and systems of displaying flow-volume loops of a patient and variability of the flow-volume loops across measured breaths are disclosed. The methods comprise obtaining a physiological dataset of the patient on a data acquisition device, applying a smoothing and curve fitting algorithm to the physiological dataset on a processing device to obtain real-time volume and flow data at a plurality of time instances, applying a visualization algorithm on the processing device to the volume and flow data to create a series of flow-volume loops based on the volume and flow data, and outputting a plot of the flow-volume loops on a display device to aid evaluation or diagnosis of the patient.

Abstract: Systems and methods for measurement of end tidal carbon dioxide, including a device having a body and a tubular gas line. The body is adapted to be attached to a patient airway and has a first gas line securing portion which has an aperture through it and is adapted to secure the gas line to the body. The tubular gas line is secured in the aperture. The tubular gas line has a proximal portion extending from a proximal end of the aperture and has a proximal end which is adapted to be connected to an end tidal CO2 monitor. The tubular gas line also has a distal portion extending from a distal end of the aperture and having a distal end which provides an inlet for end tidal CO2 exhaled by a patient.

Abstract: Apparatus is disclosed for measuring the circumference of a limb of an individual, e.g., the individual's arm and/or calf. The apparatus uses one or more magnetic strips which surround the limb and contain magnetic coding of length information. Tension is applied to the magnetic strip by a tensioning assembly, which can be a pressure cuff or a stepping motor, and a magnetic read head reads the magnetic coding of length information from the strip. When used in a bioimpedance analysis procedure, the length information can be used to convert measured voltage differences into normalized bioimpedance values, e.g., resistivity values.

Abstract: A portable laser height measuring system including an upper assembly including an elongated top flat plate attached to an upper back plate, wherein the elongated top flat plate includes a top side and an underside is disclosed herein. A separate lower assembly including a base is attached to a bottom backplate. A laser measurement device is affixed to the elongated top flat surface. A leveling device is mounted at one end of the elongated top flat plate proximate the laser measurement device; and a data collection device is electronically coupled to receive signals from the laser measurement device.

Abstract: A system for managing subject data relating to a body status of a subject, the system including one or more subject databases storing subject data for a plurality of subjects, the subject data being indicative of body status indicator and measured body parameter values of the subject and one or more processing devices that receives collected subject data from a client device via a communications network, the client device receiving measurement data indicative of at least one measured body parameter value of a subject from a measuring device, and the collected subject data being indicative of at least one of the measurement data and the at least one measured body parameter value and determines an identity of the subject, updates the subject data for the subject using the collected subject data and retrieves retrieved subject data for the subject, the retrieved subject data being indicative of measured body parameter values for the respective subject and being used to derive a body status indicator indicative o

Abstract: A body movement feedback system including at least one position sensor operative to sense in real time at least relative positions of mutually articulated body portions of a user and to provide sensor outputs, a mutually articulated body portion position processor, receiving the sensor outputs of the at least one position sensor and providing processor outputs representing relative movements of the mutually articulated body portions and a real time user feedback generator operative to generate predetermined feedback to the user in response to predetermined selected movements of the mutually articulated body portions.

Abstract: An object is to appropriately detect various activities of a detection target. An electronic device transmits information characterizing the activity of a detection target, and an activity detection device acquires, from its sensor section, a sensing motion signal that is motion information which successively fluctuates in accordance with motions of the detection target as first information. The activity detection device also acquires, from the electronic device, the information characterizing the activity of the detection target as second information, and identifies the type of the activity of the detection target by using the acquired first and second information.

Abstract: A fingerprint reading device that can suppress a position shift of a finger, that includes: a placement portion on which a finger is placed; a reading face; a pair of light sources provided on the placement portion and that irradiate the finger with lights; and a reading unit that captures and reads a fingerprint of the finger in contact with the reading face in accordance with lights scattered in the finger and emitted from a surface of the finger, the pair of light sources are provided on both ends of the reading face that are opposed to each other in a width direction of the placement portion and have light guiding parts formed in a front-back direction of the placement portion, respectively, and the light guiding parts are formed so as to extend up to above the ends of the reading face.

Abstract: Described and disclosed herein are various embodiments of systems, devices, components and methods configured to employ acoustic coordinated reset neuromodulation therapies that are capable of adjusting or modulating at least one of the intensity, auditory filter bandwidth, and center frequency of therapeutic stimulation signals delivered to an individual patient, where in one embodiment such signals are tuned to have intensities that are above or slightly above the individual patient's hearing threshold.

Abstract: The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.

Abstract: Analyte monitoring systems, devices, and methods associated with analyte monitoring devices, and devices incorporating the same are provided. Various graphical user interfaces (GUI) and navigation flows are provided for performing various features, activities, functions, etc., associated with the analyte monitoring device or system. Intuitive navigation is provided to enhance the interpretation of analyte measurements.

Abstract: The disclosed invention includes methods to employ wearable biosensing devices to accomplish the following: 1) screen for the presence of a disease or infection, including pre-symptomatic detection, and determination of the type (e.g., viral, bacterial, or fungal) of disease or infection present; 2) confirm the antigen and monitor the progress of an active infection; and 3) monitor the efficacy of a treatment program for a disease or infection. Such methods rely on the detection, in sweat or other biofluids, of proteins, nucleotides, DNA polymerases, proteases, group-specific antigens, antibodies, cytokines, or other molecules, that are produced by the body as part of the innate or adaptive immune responses to an infectious agent, or the infectious agent itself, its products, or derivatives. Some embodiments comprise a method of using such a biosensing device as a biosentinel against biological threats.

Abstract: The invention provides for a system for in vivo real time measurement of NADH recovery kinetics, comprising: 1) a specific pulse sequence to non-destructively, yet effectively, photobleach NADH for measurement of NADH recovery kinetics; 2) illumination light parameters to acquire NADH fluorescence before and after photobleaching, without causing fluorescence bleaching artifacts, for measurement of NADH recovery kinetics; and 3) configurations for devices capable of photobleaching NADH by at least 10% within tissues for effective measurement of NADH recovery kinetics in tissues within a living subject or excised tissues and organs.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract: The present invention described a system for an energized ophthalmic device with a media insert that includes microfluidic elements upon or within the media insert. In some embodiments, the microfluidic elements may be useful for the purpose of analyzing an analyte such as glucose in a fluid sample. In addition, some embodiments can function with a medicament administering device to treat an abnormal condition identified during the analyte analysis in the fluid sample.

Abstract: The disclosed invention includes a biofluid sensing device capable of passively or actively regulating an operating temperature of one or more sensors. The device includes at least one biofluid sensor in a thermally isolated environment and at least one temperature sensor to measure sensor environment temperature. Some embodiments include at least one thermal adjustor to regulate the sensor temperature by actively regulating the sensor environment temperature in response to a signal from the temperature sensor. The invention also includes a method of regulating temperature for a biofluid sensing device having a sensor for measuring an analyte in the biofluid. The method includes measuring a biofluid sensor temperature, regulating the sensor temperature to within a selected range of the measured sensor temperature, and maintaining sensor temperature within the selected range of the measured temperature throughout device operation. In some embodiments, the measured temperature is a calibration temperature.

Abstract: A computer-implemented method includes: receiving, by a computing device, information identifying a user's activity; determining, by the computing device, the user's tasks based on the information identifying the user's activity; determining, by the computing device, the user's context switches based on the user's tasks; receiving, by the computing device, biometrics data associated with the user via an application programming interface (API); determining, by the computing device, the user's stress levels at various times based on the biometrics data; storing, by the computing device, information linking the user's stress level with the user's context switches; and outputting, by the computing device, the information linking the user's stress level with the user's context switches.

Abstract: A cognitive urinary tract microcomputer is provided. The cognitive urinary tract microcomputer includes a propulsion device for moving the cognitive urinary tract microcomputer through a urinary tract. The cognitive urinary tract microcomputer further includes an image sensor for capturing images of the urinary tract. The cognitive urinary tract microcomputer also includes a computer having an image processor and a memory. The memory stores a cognitive algorithm executed by the image processor for comparing images of normal urinary tract segments to the captured images to detect abnormalities in the urinary tract and provide an indication of the abnormalities to a user.

Abstract: A hemoencepholagraphy neurofeedback device includes a headband assembly, and a circuit board coupled to said headband strap. The circuit board includes at least a pair of light emitting diodes, a receiver and a microprocessor. The pair of diodes includes a red light and an infrared light. When the pair of light emitting diodes are emitted onto a user's forehead, the receiver measures the amount of light returned from the forehead, and a display device or software application displays the microprocessor's calculation of the amount of blood flow in the area of the user's forehead. The neurofeedback device may be wirelessly connected to a mobile device or software application. The neurofeedback device allows the user to quantify the amount of blood flow in the brain, causing the growth of new blood vessels in the brain in the areas where the neurofeedback is used.

Abstract: A system and method for detecting brain concussion includes detecting and measuring of acceleration at one or more points on a subject's head. Sensors, which can be accelerometers placed against the head, detect and measure natural motions of the patient's head due to blood flow in the brain and resultant movement of tissue in the brain. The acceleration data are then analyzed, including as to frequency of motions of the skull at the subject location in a frequency range of about 1 to 20 Hz. An observation is then made, as compared with data corresponding to non-concussion, of a change in frequency response pattern exhibited when accelerations are plotted as a function of time or frequency, to identify probable concussion if the frequency response pattern indicates concussion. Preferably the observation and comparison are made by a computer using an algorithm.

Abstract: A device is provided for diagnostic measurement by simultaneous multimodal analysis of a subject's head wherein the cerebral blood flow variations as well as the concentration level of oxygenation in the subject's blood are used to determine the presence and the pathophysiology of neurocognitive disorders, including the neurodegenerative disease referred to as Alzheimer's disease.

Abstract: A method and system for detecting a probability of psychogenic non-epileptic seizures comprising a portable battery powered device placed on the body of a patient and means for manually logging detected seizures within a time period. The device may advantagely comprise a seizure detection algorithm which automatically records seizures detected within that time period. The two sets of data may then be transferred to a second device where the logged time stamps are matched to the recorded time stamps for determining if the detected seizure is a GTCS or might be a PNES. This provides a cheap and simple method for registering a probability of PNES by using a seizure detection device comprising an EMG-sensor or an accelerometer.

Abstract: There are provided a micro-needle patch for diagnosing and treating an allergy disease which can easily and effectively inject an allergen into a dermal layer of an entity, a method for producing the micro-needle patch, and a method for diagnosing an allergy disease using the micro-needle patch. The micro-needle patch includes a plurality of micro-needles constructed to inject an allergen into an entity; and a pad for supporting the plurality of micro-needles. The micro-needle patch in accordance with the present disclosure may inject the allergen easily and effectively into the dermis of the entity, thereby to allow diagnosing or treating the allergy disease easily and efficiently without causing great pain to the patient. Further, controlling the type and content of the allergen contained in the micro-needle patch may allow diagnosing or treating allergy diseases accurately.

Abstract: A method of treating sepsis and septic shock is using a passive simulated exercise device is disclosed. The exercise device functions to increase pulsatile shear stress (friction) to the vascular endothelium. Increased shear stress stimulates release of beneficial mediators from the endothelium into the circulation that promote integrity of the endothelial barrier as well as to prevent its disruption by suppressing inflammation and oxidative stress. The latter is the basis for the deleterious effects of sepsis and septic shock. Failure to control integrity of the endothelial barrier promotes excessive leakage of fluid and proteins from the vasculature into surrounding interstitial fluid that can rapidly escalate into major morbidity, shock and death.

Abstract: An intraoral moisture measuring device includes: a swing member that swings with respect to a main body about a predetermined swing center; a moisture amount detection unit provided at a tip of the swing member, for detecting a moisture amount by being directly or indirectly abutted against a measurement site in a mouth; and a biasing member for biasing the swing member in one of swing directions. Consequently, the intraoral moisture measuring device is capable of measuring intraoral moisture in a simple and highly-accurate manner.

Abstract: A breast volume measurement apparatus includes a volume measurement section, a nipple spacing, an opening for intervention, a plurality of tissue control gaps, and a plurality of fixation channels. The breast volume measurement apparatus is developed in order to ensure symmetry between two breasts during therapeutic or cosmetic breast surgery and to guide the surgeon in terms of breast size reduction ratios.

Abstract: Devices and methods for determining the thickness of hair are provided. An exemplary device includes a computing unit with a processor and a local memory. The processor is connected to the local memory and configured to read data from and/or to write data into the local memory. The device further includes a user input/output unit configured for interaction with a user. Also, the computing unit includes an image data input interface for receiving image data of at least one individual hair. The image data input interface is connected to the processor. Further, the computing unit includes a user interface connected to the user input/output unit and to the processor. The computing unit is configured to process the image data of the at least one individual hair to create hair thickness values of the at least one individual hair and to output the hair thickness values to the user interface.

Abstract: Methods, systems, and computer readable media for non-invasively predicting patient-specific mechanical competence at an anatomical site. In some examples, a method includes receiving images from the anatomical site of a patient; using computational analysis of the images to simulate mechanical loading at the anatomical site; and generating, based on the analysis, an indication of stiffness, strength, resilience or toughness under the mechanical loading conditions.

Abstract: A method of generating a correction plan for a knee of a patient includes obtaining a ratio of reference bone density to reference ligament tension in a reference population. A bone of the knee of the patient may be imaged. From the image of the bone, a first dataset may be determined including at least one site of ligament attachment and existing dwell points of a medial femoral condyle and lateral femoral condyle of the patient on a tibia of the patient. Desired positions of contact in three dimensions of the femoral condyles of the patient with the tibia of the patient may be obtained by determining a relationship in which a ratio of bone density to ligament tension of the patient is substantially equal to the ratio of reference bone density to reference ligament tension.

Abstract: A system 1, a corresponding method and computer program for assisting exercising of a subject 7 is provided. The system comprises: an exercise state providing unit 10 for providing an exercise state of the subject 7 for or during an exercise session, a fatigue level determination unit 20 for determining a fatigue level of the subject 7 based on the exercise state of the subject 7, a fatigue level threshold determination unit 30 for determining a fatigue level threshold for the subject 7 for the exercise session, and an evaluation unit 40 for evaluating the fatigue level in comparison to the fatigue level threshold. It provides a more versatile system 1 for assisting exercising of a subject 7 and further provides an improved exercising assistance for the subject 7.

Abstract: This terminal device is provided with: a biological signal acquisition unit which acquires a biological signal of a person to be measured; a biological information acquisition unit which acquires, on the basis of the acquired biological signal, biological information on the person to be measured; a determination unit which determines whether the biological information on the person to be measured is accurate in the time period in which the biological signal is measured; and a control unit which changes the handling of the biological signal or the biological information according to the determination result from the determination unit.

Abstract: The present invention relates to a determination system, a corresponding determination method and a computer program for determining a sleep stage of a subject. The determination system comprises a cardiorespiratory signal providing unit (10), an actigraphy data providing unit (20), a first sleep stage determination unit (30) for determining the sleep stage based on a cardiorespiratory signal, and a second sleep stage determination unit (40) for determining the sleep stage based on actigraphy data. The first sleep stage determination unit (30) determines a sleep onset latency (SOL) of the subject. The sleep stage of the subject is determined using the first sleep stage determination unit (30) up to the SOL and the second sleep stage determination unit (40) after the SOL. The determination system and corresponding method allow for a more reliable determination of a sleep stage of subject, in particular improve the determination of the SOL of the subject.

Abstract: Disclosed is a method and a system implementing the method for determining an optimal time window for sleep of a person. The method includes receiving samples of a distal skin temperature of the person, and detecting a temperature change pattern in the samples of distal skin temperature. The temperature change pattern indicates a reference point within the circadian rhythm. The optimal time window for sleep is determined on the basis of the indicated reference point. The temperature change pattern is in the form of a drop in the distal skin temperature followed an increase in the distal skin temperature, where the drop and the increase occur within a time window of ten minutes or less.

Abstract: A method for evaluating skin conditions on a skin area of a user using an ultraviolet light device that can connect to a mobile device and a user input is disclosed. The method for evaluating skin conditions includes the steps of illuminating the skin area of the user with the ultraviolet light device operated by the mobile device, capturing an image of the illuminated skin area with an image capture device, processing the image with a processing program to determine the level of fluorescence on the skin area, and mapping progress of treatment of the skin condition based on the processed image compared to a control image.

Abstract: Systems and methods for classifying breathing disorders of subjects are based on the respiratory response to a change in a pressure level of a pressurized flow of breathable gas. The change presents a breathing challenge to a subject. The challenge may be limited to the inspiratory breathing phase. The inspiratory pressure level may be lower than the expiratory pressure level during challenges.

Abstract: The present invention relates to a mind-altering substance testing unit. The unit includes a display module for displaying an indication of a drug or alcohol. A sensor module is releasably fastened to the display module and includes sensors for sensing the drug and alcohol. The unit also includes a sample cartridge for receiving a sample and for releasably fastening to the sensor module so that the sensor module can sense the drug. Advantageously, the same testing unit can be used to sense alcohol and the drug avoiding the need for separate testing units.

Abstract: An information processing apparatus includes: a memory; and a processor coupled to the memory and configured to: acquire activity amount data corresponding to activity of a subject which is measured by an activity amount meter; and detect a biorhythm of the subject from a result of frequency analysis of a time waveform of the activity amount data and visualize information on an action recommended to the subject with respect to the detected biorhythm.

Abstract: A skin observation system includes a helmet to be placed over the head of a user, a mirror disposed within the helmet in a direct line of sight of the user wearing the helmet, at least one lighting device disposed within the helmet for illuminating the face of the user, a shield disposed within the helmet for shielding the eyes of the user from light emitted by the at least one lighting device, and a filter disposed within the helmet for filtering components of the light emitted by the at least one lighting device. The lighting device is preferably a plurality of laser diodes and the filter is preferably a UV filter. The mirror preferably has a concave surface facing the user.

Abstract: A sensor is disclosed comprising, in at least one embodiment an electrode, a track and an electrical connector, wherein, the track is comprising an electrically conductive flexible and elastic material that comprises an electrically conductive material that is non-contiguous that when stretched is able to transmit an electrical signal from an electrode to an electrical connector and from an electrical connector to an electrode.

Abstract: The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home.

Abstract: An apparatus and wearable electronic device wherein the apparatus comprises: a flexible member arranged to be wrapped around part of a subject's body, the flexible member comprising a first end portion and a second end portion; a magnetic arrangement embedded within the flexible member wherein the magnetic arrangement comprises at least one magnet positioned within the first end portion of the flexible member and at least one magnetic portion positioned within the second end portion of the flexible member; and wherein the magnetic arrangement is arranged to hold the first end portion of the flexible member in position relative to the second end portion when the flexible member is bent so that the first end portion and the second end portion overlap.

Abstract: An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

Abstract: A method and system for low-distortion denoising of an ECG signal are disclosed. The method comprises determining at least one beat of the ECG signal for denoising using a beat selection logic and denoising the at least one beat using at least one ensemble averaging filter. The system includes a sensor to detect the ECG signal, a processor coupled to the sensor, wherein the processor includes a beat selection logic unit, and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to determine at least one beat of the ECG signal for denoising using a beat selection logic and to denoise the at least one beat using at least one ensemble averaging filter.