Patents Issued in July 2, 2019
  • Patent number: 10335339
    Abstract: A pivoting examination chair mechanism for an examination chair related to a substantially immovable examination tool, which includes a rotation mechanism portion rotating about a first vertical axis, a rotation arm integral with, and extending from, the rotation mechanism portion, and a chair support portion attached proximate a distal end of the rotation arm and offset from the rotating base portion including a chair gimbal, in which the chair gimbal rotates around a second vertical axis and the first and second vertical axes are substantially parallel to one another, so that moving the rotation arm through 180°, the examination chair is moved about the first vertical axis to provide a clear access area to the substantially immovable examination tool.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: July 2, 2019
    Inventor: Susan Stees
  • Patent number: 10335340
    Abstract: The Mobile Dental Intelligence Center (MobiDIC) will roll up alongside the patient's Bedside or Chairside where Oral Hygiene can be performed by the patient's Caregiver, with no need to have a sink or basin in the area. Using the MobiDIC the Caregiver will be able to brush the patient's teeth, rinse and suction the patient's mouth at the Bedside or Chairside; also the Caregiver will monitor the patients Vital Signs. The unit's unique cylindrical design makes it easy for the Caregiver to wipe clean and disinfect the unit. The air, water, suction and power supply hoses are internal to the unit reducing cord entanglement and trip hazards. The MobiDIC allows the Caregiver the ability to easily connect various medical monitoring devices including Intra and Extra Oral Cameras capturing images of the patient's mouth inside and the patient's general appearance. All MobiDIC innovations will facilitate assessing the patient's current general health.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 2, 2019
    Assignee: Dr. Kevin T. Prince
    Inventor: KevinTyrone Prince
  • Patent number: 10335341
    Abstract: A walking assistance method and apparatus, in detail, a control device that may estimate a gait motion of a user based on pressure data indicating information on a pressure applied to a sole of the user, and provide a feedback corresponding to the gait motion to the user by controlling a vibrator to apply a vibration to the sole of the user, is provided.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: July 2, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Youngbo Shim, Jongwon Lee, Youngjin Park, Sunghwan Ahn, Seungyong Hyung
  • Patent number: 10335342
    Abstract: Exemplary embodiments of the present disclosure relate to systems, methods, and apparatus for vision therapy. In exemplary embodiments a visual therapy game can be rendered on one or more displays and the visual therapy game can be controlled by eye movements of the user. Visual stimuli incorporated in the visual therapy game can be rendered to facilitate vergence eye movements for the treatment of binocular dysfunctions.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: July 2, 2019
    Assignee: New Jersey Institute of Technology
    Inventors: Tara Lynn Alvarez, John Vito D'Antonio-Bertagnolli, Robert Gioia, Mitchell Scheiman, Chang Yaramothu
  • Patent number: 10335343
    Abstract: A method and devices for stimulating visceral pelvic or somatic nerves or their pathways of a female person suffering from a pelvic condition of nerve dysfunction in which non-electrical, external physical stimulation is applied to the clitoral region of the person.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: July 2, 2019
    Assignee: ParaPatch, Inc.
    Inventors: Cora St. Anne, Theodore V. Benderev
  • Patent number: 10335344
    Abstract: Provided is a technology of a handy type and small-sized massage appliance. In the massage appliance, the vibrating section which is brought in contact with the user's skin and applies vibration is covered by the dual-structured cladding material having a high flexibility. Therefore, the original massage effect such as the promotion of bloodstream, the removal of the body wastes, and recovery from fatigue can be exerted without giving damage on a sensitive diseased part or the skin. There are provided a motor 5, a vibrating piece 8 which is rotatably driven by the motor, a vibrator body 2 which includes the case 9 accommodating these components, a soft cover 20 which surrounds the outer surface of the case, and a super-soft resin 40 which is interposed between the outer surface of the case and the soft cover and integrates the case and the soft cover.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: July 2, 2019
    Assignee: TENGA CO., LTD.
    Inventor: Tsutomu Matsuura
  • Patent number: 10335345
    Abstract: A vibration device for generating vibration using sound pressure includes a cone paper damper generating vibration and a bobbin guiding a voice coil to allow the same to be stably provided. A connection member and a vibration probe are coupled at the center of the upper surface of the cone paper damper and the bobbin. The vibration device directly receives the vibration, which is generated from the cone paper damper, and transmits the vibration to the vibration probe. In addition, a human-body stimulation apparatus includes the vibration device having a cone paper damper for generating vibration and a bobbin for guiding a voice coil to allow the voice coil to be stably provided. The human-body stimulation apparatus receives a sound source using various forms of interfaces for storing or providing the sound source.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: July 2, 2019
    Assignee: EVOSONIC CO., LTD.
    Inventor: Jae Yeong Choe
  • Patent number: 10335346
    Abstract: Embodiments of the present invention are related to a method and device for the determination and calculation of the depth of chest compressions during the administration of cardiopulmonary resuscitation (CPR). Embodiments use an optical sensor to monitor the distance that a victim's chest is displaced during each compression throughout the administration of CPR. The optical sensor is most commonly an image sensor such as a CMOS or CCD sensor, and more specifically a CMOS image sensor capable of three-dimensional imaging based on the time-of-flight principle. An infrared emitter may illuminate the victim's body and any visible piece of ground beside the victim. As the infrared light interacts with any surfaces it encounters, it is reflected and returns to the image sensor where the time of flight of the infrared light is calculated for every pixel in the image sensor. The distance data is used to gauge the effective displacement of the victim's chest.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: July 2, 2019
    Assignee: PHYSIO-CONTROL CANADA SALES LTD.
    Inventor: Corey James Centen
  • Patent number: 10335347
    Abstract: The invention relates to a closing system for a container to be held with a single hand. The closing system includes a cap having a skirt and a transversal wall provided with an access port, and a cover substantially parallel to the cap and with a guiding member intended to be used by a user to manipulate the cover. A hinge allows a planar rotation of the cover regarding the cap from a first position to close the access port to a second position to access the access port.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: July 2, 2019
    Assignee: Becton Dickinson France
    Inventors: Franck Carrel, Lionel Maritan, Frederic Perot, Maxime Vaupres, Jean-Yves Corbin
  • Patent number: 10335348
    Abstract: A filling needle can be used in a tube set for transferring a flowable medium, in particular a pharmaceutical product. The filling needle has a needle end for temporary insertion in a filling vessel. Furthermore, the filling needle has a connector end for connecting the filling needle to a filling vessel, via which the medium can be supplied to the filling needle. An inner tube lumen of the filling needle is defined by an inner tube layer made of silicone. The result is a filling needle that can be manufactured inexpensively.
    Type: Grant
    Filed: November 12, 2016
    Date of Patent: July 2, 2019
    Assignee: Raumedic AG
    Inventors: Philipp Jordan, Steffen Hager, Dominik Erhard, Rainer Adelung, Kristin Mess, Ingo Paulowicz, Fabian Schütt
  • Patent number: 10335349
    Abstract: A container storing pills or other discrete objects and which provides restricted access to the pills. The container has a rotatable pill drum allowing selective access to pills when the drum is rotated to various dispensing positions. A rotatable combination disk or other component is provided that has a plurality of channels formed therein and which can be rotationally locked to the drum. Movable pegs engage the channels. Each dispensing position has an associated peg position combination. Rotation of the pill drum from one dispensing position to the next is blocked unless the pegs are moved into the appropriate peg position combination. The pill drum can be rotated from one dispensing position to the next using a handle or via an automatic spring loaded mechanism.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: July 2, 2019
    Assignee: Addinex Technologies, Inc.
    Inventors: Stanislav Roslyakov, Jay Howard Schiff
  • Patent number: 10335350
    Abstract: A new and improved pacifier provides bristle like structures which discourages continued use of the pacifier by a child of appropriate age.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: July 2, 2019
    Inventor: Soheil Khodadadi
  • Patent number: 10335351
    Abstract: A personal care article can include a composition and a substrate. The article can be compliant to a surface.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: July 2, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Edward Dewey Smith, III, Shawn David McConaughy
  • Patent number: 10335352
    Abstract: The subject of the present disclosure is agents for oxidative hair coloring containing from about 70 about 95 wt. % water, oxidation dye precursor(s), alkalizing agent, from about 0.1-about 2 wt. % anionic, zwitterionic or amphoteric surfactant, and a mixture of sodium polyacrylate, crosslinked copolymers of acrylic acid and non-ethoxylated esters of acrylic acid with linear C10-C30-monoalcohols, branched C10-C50-alcohol and linear, saturated C8-C22-alkan-1-ol, wherein the dye receives optimal viscosity for application and the consistency of a cream-like gel with outstanding haptics.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 2, 2019
    Assignee: Henkel AG & Co. KGaA
    Inventors: Juergen Schoepgens, Burkhard Mueller
  • Patent number: 10335353
    Abstract: The subject of the present disclosure is agents for oxidative hair dyeing containing from about 70-about 86 wt. % water, oxidation dye precursor(s), alkalizing agent and a specific mixture of a crosslinked copolymer of acrylic acid and non-ethoxylated esters of acrylic acid with linear C10-C30-monoalcohols, surfactic, cationic or zwitterionic polymer and linear, saturated C8-C22-alkan-1-ol, wherein the dye obtains the optimal viscosity for application and the consistency of a gel-like cream with outstanding haptics.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 2, 2019
    Assignee: Henkel AG & Co. KGaA
    Inventors: Juergen Schoepgens, Burkhard Mueller
  • Patent number: 10335354
    Abstract: The invention provides the use of at least one alkyl-phthalide or a plant extract comprising mainly said alkyl-phthalide for the topical cosmetic treatment of the skin and of the scalp, in particular an anti-dandruff treatment. According to the invention, a CO2 supercritical extract of Apium graveolens seeds consisting mainly of sedanenolide may be used.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: July 2, 2019
    Assignee: SEDERMA
    Inventors: Olga Gracioso, Caroline Ringenbach, Thibault Marchand, Philippe Mondon, Nicolas Barriere
  • Patent number: 10335355
    Abstract: The invention thus relates to the cosmetic use of a siliceous material that may be obtained by hydrolysis and condensation, in the presence of water, of at least one tetraalkoxysilane of formula (I) below: Si(OR1)4 (I) and of at least one aminoalkyl-trialkoxysilane of formula (II) below: R2Si(OR3)3 (II) R1 denotes a linear or branched C1-C4 alkyl group; R2 denotes a linear or branched, saturated or unsaturated C1-C6 hydrocarbon-based group, a cyclic C3-C5 hydro-carbon-based group, or denotes a C6-C9 aryl or C6-C9 aryloxy group; the said radicals being substituted with an amino group NH2 or NHR with R denoting a linear or branched C1-C4 alkyl group; R3 denotes a linear or branched C1-C4 alkyl group; the said material being other than a molecularly imprinted polymer.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: July 2, 2019
    Assignee: L'OREAL
    Inventor: Andrew Greaves
  • Patent number: 10335356
    Abstract: The present invention discloses a use of neohesperidin or a neohesperidin-containing plant extract in the manufacture of a product for improving and/or promoting skin microcirculation, or for eliminating and/or alleviating diseases or conditions associated with poor skin microcirculation. The present invention also discloses a composition comprising an effective amount of neohesperidin or a neohesperidin-containing plant extract, and to a method for improving and/or promoting skin microcirculation, or eliminating and/or alleviating diseases or conditions associated with poor skin microcirculation, by using neohesperidin. The skin microcirculation of the present invention is preferably eye skin microcirculation.
    Type: Grant
    Filed: November 25, 2011
    Date of Patent: July 2, 2019
    Assignee: Natural Medicine Institute of Zhejiang Yangshengtang Co., Ltd.
    Inventors: Liu Hu, Hongying Lan
  • Patent number: 10335357
    Abstract: A water-in-oil emulsion comprising less than 60% water, and wherein said emulsion comprises an oil phase and a water phase, and wherein the water phase comprises a dipeptide selected from the group consisting of acetyl dipeptide (1) cetyl ester, acetyl dipeptide (3) aminohexanoate, azelaoyl bisdipeptide (10), coumaroyl dipeptide (3), dicetyl dipeptide (9), dipeptide diamino butyroyl benzylamide diacetate, dipeptide (1), dipeptide (10), dipeptide (11), dipeptide (12), dipeptide (15), dipeptide (16), dipeptide (17), dipeptide (18), dipeptide (19), dipeptide (2), dipeptide (20), dipeptide (3), dipeptide (4), dipeptide (5), dipeptide (6), dipeptide (7), dipeptide (8), dipeptide (8) HCL, dipeptide (9), hexanoyl dipeptide (3) norleucine acetate, methyl undecylenoyl dipeptide (16), nicotinoyl dipeptide (22), nicotinoyl dipeptide (23), nicotinoyl dipeptide (24), nicotinoyl dipeptide (26), oleoyl dipeptide (15), palmitoyl dipeptide (10), palmitoyl dipeptide (13), palmitoyl dipeptidel (7), palmitoyl dipeptide (5) diami
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: July 2, 2019
    Assignee: THE BOOTS COMPANY PLC
    Inventors: Paul James Tomlinson, Mark Johnson, Michael David Bell
  • Patent number: 10335358
    Abstract: A hair cosmetic comprising the following ingredients (A) and (B): (A) a cationic polymer having a charge density of 5.0 to 7.0 meq/g and (B) an anionic polysaccharide derivative wherein a part of the H atoms of the OH group of a polysaccharide compound having the constituent unit described below are substituted with a —(CH2)mCOO? group (m is an integer of 1 to 5) at an average substitution degree of 0.5 to 2.0 per constituent unit, and wherein optionally a part of the H atoms of the remaining —OH groups are substituted with C1-40 alkyl groups and/or alkylene groups, wherein the viscosity of the ingredient (B) in a 2 mass % aqueous solution (25° C.) is 0.5 to 800 mPa·s wherein R? represents a C2-4 alkylene group optionally substituted with an —OH group, and n represents a number by which the average number of added moles of R?O per constituent unit is 0 to 10.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: July 2, 2019
    Assignee: KAO CORPORATION
    Inventors: Yu Horie, Kenji Hozumi, Takashi Mizooku, Hiroto Tanamachi
  • Patent number: 10335359
    Abstract: A hair fixative composition includes at least one carboxylated cellulose ester based polyglucose polymer, an alcohol based solvent system, and a cosmetically acceptable additive. The polyglucose polymer is obtained by reacting at least one cellulose ester with a non-aromatic cyclic anhydride and neutralizing the reaction product thereof. The polyglucose polymer is soluble in the alcohol based solvent system.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: July 2, 2019
    Assignee: AKZO NOBEL CHEMICALS INTERNATIONAL B.V.
    Inventor: Hanamanthsa Bevinakatti
  • Patent number: 10335360
    Abstract: A disposable toothbrush having a toothpaste composition distributed over the bristles of the toothbrush without the use of metal graft initiators and catalysts, and in which the toothpaste and the flavoring is maintained for an extended period of time.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: July 2, 2019
    Inventor: Steven Zaken
  • Patent number: 10335361
    Abstract: A cosmetic process for making-up and/or caring for skin and/or lips, includes the application to skin and/or lips of a cosmetic composition including, in a physiologically acceptable medium, at least one supramolecular polymer and at least one hydrophobic film-forming polymer. Particular compositions may be used in the process.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: July 2, 2019
    Assignee: L'OREAL
    Inventors: Roberto Cavazzuti, Nathalie Geffroy, Gaelle Brun
  • Patent number: 10335362
    Abstract: The purpose of the present invention is to provide a water-in-oil type cosmetic which ensures emulsion stability in the case where a volatile hydrocarbon oil component is added, has excellent texture such as not leaving a greasy feeling, and is highly compatible with the skin. The present invention relates to a water-in-oil type emulsified cosmetic comprising: (A) 20 to 30 mass % of an oil component; (B) a fatty acid ester having an HLB of 5 to 10; (C) a nonionic surfactant having an HLB of 1 to 4; (D) an organic modified clay mineral; and (E) water, wherein volatile hydrocarbon oil accounts for 10 mass % or more of the oil component (A) and silicone oil is not contained.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: July 2, 2019
    Assignee: SHISEIDO COMPANY, LTD.
    Inventors: Kazutaka Sasaki, Takayuki Omura, Masaki Kitajima
  • Patent number: 10335363
    Abstract: Topical skin care compositions that include bioactive ingredients derived from achachairu and methods of making the same. The bioactive compositions (ingredients) of the present invention may be free of or substantially free of benzophenones and/or protein, and may exhibit anti-inflammatory, anti-oxidant, and/or anti-aging properties. The achachairu ingredient may be in the form of a serum fraction and/or an extract.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: July 2, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Rosemarie Osborne, Lisa Ann Mullins, Michael Koganov
  • Patent number: 10335364
    Abstract: A preparation for topical application comprising glycerol and plant tannins, wherein the plant tannins have the capacity to bind to glycerol so that the glycerol has filmogen quality.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: July 2, 2019
    Inventors: Remi Shrivastava, Lea Shrivastava, Ravi Shrivastava
  • Patent number: 10335365
    Abstract: The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO: 1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.
    Type: Grant
    Filed: January 7, 2017
    Date of Patent: July 2, 2019
    Assignees: The Regents ot the Univershy of California, The United States of America as represented by the Department of Veteran Affairs (Washington DC)
    Inventors: Chong-Xian Pan, Hongyong Zhang, Kit S. Lam, Olulanu H. Aina
  • Patent number: 10335366
    Abstract: The present invention is directed to an injectable intramuscular depot composition suitable for forming an in situ solid implant in a body, comprising a drug which is risperidone and/or paliperidone or any pharmaceutically acceptable salt thereof in any combination, a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid of about 50:50 and a DMSO solvent, wherein the composition releases the drug with an immediate onset of action and continuously for at least 4 weeks and wherein the composition has a pharmacokinetic profile in vivo that makes it suitable to be administered each 4 weeks or even longer periods.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: July 2, 2019
    Assignee: Laboratorios Farmacéuticos Rovi, S.A.
    Inventors: Ibon Gutierro Aduriz, Guillermo Franco Rodríguez
  • Patent number: 10335367
    Abstract: Selected anticholinergic zwittehons are administered to slow the progression of myopia in children and to treat myopia generally.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: July 2, 2019
    Assignee: BODOR LABORATORIES, INC.
    Inventor: Nicholas S. Bodor
  • Patent number: 10335368
    Abstract: The present invention is directed to compositions and methods for delivering a tissue scaffold comprising ultrasound-triggerable agents to an individual.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: July 2, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Mario L. Fabiilli, Christopher Wilson, Frederic Padilla, Francisco Martin-Saavedra
  • Patent number: 10335369
    Abstract: The invention relates to granules and pharmaceutical compositions comprising a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant obtained by mixing hereof for more than 5 minutes prior to granulation as well as processes for their preparation and use thereof in medicine.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 2, 2019
    Assignee: Novo Nordisk A/S
    Inventor: Thomas Vilhelmsen
  • Patent number: 10335370
    Abstract: The present disclosure provides a controlled release composition comprising a plurality of microparticles and a matrix, wherein: the plurality of microparticles comprises a first material; the matrix comprises a second material; and the melting temperature of the first material is higher than the melting temperature of the second material. Also provided are methods of making and using the same.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: July 2, 2019
    Inventors: Jianjian Xu, Shiliang Wang, Manzhi Ding
  • Patent number: 10335371
    Abstract: The present invention relates to solid pharmaceutical dosage forms suitable for use as drinking water medication. More in particular, the present invention provides solid pharmaceutical dosage forms comprising a pharmaceutically active agent, a non-ionic surfactant having an Hydrophilic Lipophilic Balance (HLB) of at least 8, and a maltodextrin. The present invention also provides the use of such pharmaceutical dosage forms in veterinary medicine, more in particular as drinking water medication; as well as methods for preparing such pharmaceutical dosage forms.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: July 2, 2019
    Assignees: Universiteit Gent, Orotech NV
    Inventors: Jean-Paul Remon, Chris Vervaet, Brenda Vermeulen
  • Patent number: 10335372
    Abstract: Antiviral compositions comprising a modified nuclease, or a plurality of such modified nucleases having at least one non-natural amino acid residue substituted for a naturally occurring amino acid in a parent nuclease are provided, as are methods of use and kits providing unit dosages of such compositions.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: July 2, 2019
    Inventor: Jacob G. Applebaum
  • Patent number: 10335373
    Abstract: A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected from the group consisting of nonionic acrylic polymers and waxy materials and which provides prolonged release of the pharmacologically active ingredient, resistance against solvent extraction, resistance against grinding, and resistance against dose-dumping in aqueous ethanol.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 2, 2019
    Assignee: GRUNENTHAL GMBH
    Inventors: Klaus Wening, Lutz Barnscheid, Sebastian Schwier
  • Patent number: 10335374
    Abstract: Bacterial resistance to antibiotics is increasing worldwide creating a global threat. Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, is a bacterial infectious disease that results in over one million deaths annually. The discovery outlined here involves a tablet composition for patient administration and subsequently a new paradigm in drug delivery vehicles in vivo and in vitro and is applied to existing TB antibiotics in order to increase their efficacy. The drug delivery system is a three component complex that is administered with the TB antibiotic or a combination of TB antibiotics. The components are a saccharide or saccharides, a transition metal ion or a combination of metal ions that can bind a nitrogen and/or oxygen atom(s), and a water soluble polymer capable of aggregating and enclosing the other constituents. The three component molecular delivery approach has demonstrated ability to overcome M. tuberculosis bacterial resistance to an existing antibiotic.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: July 2, 2019
    Assignee: University System of Georgia, Valdosta State University
    Inventors: Thomas J. Manning, Sydney E. B. Plummer, Tess A. Baker
  • Patent number: 10335375
    Abstract: Described herein are abuse deterrent oral pharmaceutical compositions, methods for making the same, and methods of treatment using such compositions. In particular, oral pharmaceutical compositions that mitigate the risk of overingestion of one or more active pharmaceutical ingredients are described.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: July 2, 2019
    Assignee: Patheon Softgels, Inc.
    Inventors: Justin Hughey, Jason Vaughn
  • Patent number: 10335376
    Abstract: The present invention relates to a capsule composition of raloxifene comprising multiparticulates comprising a) a core comprising raloxifene, and b) a taste-masking coating present in amount of from about 0.5% to about 50% w/w based on the core weight.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: July 2, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Ujjwal Ranjan, Mona Dhaliwal, Mukesh Kumar Garg
  • Patent number: 10335377
    Abstract: The invention relates to a medical product for a fastening duration of at least 7 days having good skin compatibility. The medical product includes a central adhesive compartment (3) and an over-patch. The over-patch is free of active ingredients and is formed from a water-vapor-permeable back layer (1) and an adhesive polymer layer (2) that is free of active ingredients. The invention further relates to a method for the production of the foregoing medical product, and to kits of parts containing laminates of layers 1 and 2.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: July 2, 2019
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Gerhard Ritzdorf, Thomas Hille, Petra Botzem, Gabriel Wauer, Marlene Fuhrmann
  • Patent number: 10335378
    Abstract: Pharmaceutical compositions and methods of use therefor for reducing the desire to engage in smoking are disclosed. More specifically, the pharmaceutical composition utilizes an active ingredient to reduce the side effects of smoking cessation and to limit the molecular feedback caused by nicotine-mediated activation of acetylcholine receptors.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: July 2, 2019
    Assignee: Altria Client Services LLC
    Inventors: Gerd Kobal, Justin Heynekamp, Peter Reeh, Munmaya K. Mishra, Tetyana Kichko
  • Patent number: 10335379
    Abstract: The present invention relates to an oral dosage form for administration of ketamine and a method of preparing an oral dosage form for administration of ketamine, preferably once or twice a day.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: July 2, 2019
    Assignee: Develco Pharma Schweiz AG
    Inventors: Sascha Andor Manthei, Helene Rey, Marc Fischer, Olaf Mundszinger
  • Patent number: 10335380
    Abstract: The present findings point to mutant HSCs as the cause of BM neuroglial damage that compromises MSC survival and function, critically contributing to MPN pathogenesis. In this sense, the present invention shows that the niche damage triggered by the mutant HSC is essential for the development of a haematopoietic malignancy previously considered to be caused by the HSC alone. Targeting HSC niche-forming MSCs and their neural regulation paves the way to more efficient therapeutic strategies in MPN. For this purpose, the present invention shows that an efficient therapeutic strategy for the treatment of MPN lies on the administration of neuroprotective compounds, such as 4-methylcatechol, capable of protecting BM sympathetic nerve fibers. Additionally, another efficient therapeutic strategy is shown herein as the administration of selective ?3-adrenergic agonists such as BRL37344 or Mirabegron, since this strategy will compensate for deficient sympathetic stimulation of nestin+ MSCs.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: July 2, 2019
    Assignee: CNIC Fundacion Centro Nacional De Investigaciones Cardiovasculares Carlos III
    Inventors: Simon Mendez Ferrer, Lorena Arranz Salas, Joan Isern Marin
  • Patent number: 10335381
    Abstract: A stabilized formulation of triamcinolone acetonide in a bioadhesive base material is provided. The present invention further includes a method of producing a stabilized non-aqueous TAA formulation and methods of measuring the stability of such TAA formulations.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: July 2, 2019
    Assignee: University of Mississippi
    Inventors: Michael A Repka, Angela Sutterer
  • Patent number: 10335382
    Abstract: In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-?-synthase (CBS) inhibitor, or a hydrogen sulfide neutralizing agent to a patient having a cancer associated with elevated production of hydrogen sulfide.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: July 2, 2019
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Mark Hellmich, Jia Zhou, Csaba Szabo
  • Patent number: 10335383
    Abstract: Exemplary embodiments provide oat fractions, and methods of producing the oat fractions, of the species Avena Sativa that has a concentration of total Avenanthramides that is from about 2 to about 25 wt. %, and up to about 30 wt. % or more, higher than the concentration before treatment with infrared energy. The higher concentration is achieved without treatment with enzymes or exposure to fungal agents to increase the concentration of total Avenanthramides. Instead, the enhanced concentration of Avenanthramides is achieved through exposure to infrared energy for a selected period of time.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: July 2, 2019
    Assignee: The Quaker Oats Company
    Inventors: YiFang Chu, Jodee Johnson, Marianne O'Shea
  • Patent number: 10335384
    Abstract: An anxiolytic composition includes a synergistic combination of one or more of an extract of magnolia, an extract of phellodendron, an L-theanine, a whey protein composition, and/or an s-adenosylmethionine (SAMe).
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: July 2, 2019
    Assignee: NUTRAMAX LABORATORIES, INC.
    Inventors: Todd Henderson, David Griffin, David Bledsoe
  • Patent number: 10335385
    Abstract: Provided are compositions and methods for producing stable foods and beverages that contain high concentrations of additives such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols and carotenoids; oil soluble vitamins; alpha lipoic acid; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: July 2, 2019
    Assignees: Virun, Inc., Hormel Foods Corporation
    Inventors: Philip J. Bromley, Chetan S. Rao
  • Patent number: 10335386
    Abstract: The present invention relates to extracted plant lipid, comprising fatty acids in an esterified form.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: July 2, 2019
    Assignees: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, GRAINS RESEARCH AND DEVELOPMENT CORPORATION, NUSEED PTY LTD
    Inventors: James Robertson Petrie, Surinder Pal Singh, Robert Charles de Feyter
  • Patent number: 10335387
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: July 2, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 10335388
    Abstract: The present invention provides methods and pharmaceutical compositions for treating proliferative disorders. The method involves step of administering to said subject a HIF-2alpha inhibitor and an immunotherapeutic agent.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: July 2, 2019
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: John A. Josey, Eli M. Wallace, Guangzhou Han