Abstract: An optical imaging device may include a support structure and imaging channels, where each imaging channel may include a discrete optical imaging pathway. The optical imaging device may also include image capturing devices respectively associated with one of the imaging channels to capture a first set of digital photograph images of respective portions of the eye. In some embodiments, the first set of digital photograph images may overlap each other and may be stitched together such that the first set of digital photograph images form a first composite image with a first set of scallops. Additionally, the optical imaging device may be rotated to capture a second set of digital photograph images that overlap each other and may be stitched together such that the second set of digital photograph images form a second composite image with a second set of scallops positioned differently than the first set of scallops.

Abstract: System and method for fully automated end-to-end eye screening with automated medical acquisition and analysis. The system includes an eye imaging device, a mechanism that moves the imaging device, a computing platform that guides the movement mechanism, a user interface, and an electronic display device and/or printer to provide the screening, monitoring, and/or diagnosis report.

Abstract: A system or method for measuring human ocular performance can be implemented using an eye sensor, a head orientation sensor, and an electronic circuit. The device is configured for measuring vestibulo-ocular reflex, pupillometry, saccades, visual pursuit tracking, vergence, eyelid closure, dynamic visual acuity, retinal image stability, foveal fixation stability, focused position of the eyes or visual fixation of the eyes at any given moment and nystagmus. The eye sensor comprises a video camera that senses vertical movement and horizontal movement of at least one eye. The head orientation sensor senses pitch and yaw in the range of frequencies between 0.01 Hertz and 15 Hertz. The system is implemented as part of a faceguard.

Abstract: Various surgical hubs are disclosed. A surgical hub comprises a storage device; a processor coupled to the storage device; and a memory coupled to the processor. The memory stores instructions executable by the processor to: receive data from a surgical instrument coupled to the surgical hub; and determine a rate at which to transfer the data from the surgical hub to a remote cloud-based medical analytics network based on available storage capacity of the storage device.

Abstract: Methods for providing a chronically ill patient with medical alerts, pharmacological alerts and information are disclosed that include: providing a patient with a chronic illness; providing a mobile device comprising a GPS receiver, a display, a microprocessor and a wireless communication transceiver, the mobile device programmed to process encrypted medical data, medical tags and medical information through an application; providing a server comprising a central processing unit, a memory, a clock and a server communication transceiver that receives input from the wireless communication transceiver of the mobile device, the memory having encrypted medical data, medical tags and medical information stored therein for a plurality of chronically ill patients, the central processing unit programmed to implement the following method comprising: receiving encrypted medical data, medical tags and medical information from the mobile device; analyzing the encrypted medical data, medical tags and medical information fr

Abstract: A system includes implantable sensors and monitors and are operable to provide health-related feedback to users based on data received from the implantable sensors and monitors.

Abstract: A biological component measuring apparatus may include: a first light source configured to emit a first light of a first wavelength range onto an object; a second light source configured to emit a second light of a second wavelength range onto the object, the second wavelength range being different from the first wavelength range; a detector configured to detect the first light and the second light which are scattered from the object; and a processor configured to determine a scattering coefficient based on the detected first light, obtain blood vessel depth information based on the detected second light, and measure a biological component by correcting the scattering coefficient based on the blood vessel depth information.

Abstract: The technology is directed to an optical fiber scanner configured to be used in an observation device. The optical fiber scanner comprises an optical fiber guiding light therethrough. A vibration transmitting member is configured to transmit vibrations to the optical fiber. The vibration transmitting member includes a through hole defined therein through which the optical fiber extends. At least one piezoelectric element is disposed on an outer circumferential surface of the vibration transmitting member and vibrating a distal end portion of the optical fiber via the vibration transmitting member. A fixing member is disposed on a proximal end side of the vibration transmitting member. A tubular wire holding member includes a plurality of wires integrally attached for supplying a voltage to the piezoelectric element. The tubular wire holding member has a contact portion securing the plurality of wires to an outer peripheral surface of the piezoelectric element in contact therewith.

Abstract: A method for visualizing structures inside a cochlea, comprising the steps of irradiating a cochlear bone with a first laser light to ablate portions of the cochlear bone, to form a thinned area of the cochlear bone, and imaging intracochlear structures by a second light via the thinned area of the cochlear bone to optically scan targeted structures inside the cochlea.

Abstract: The invention relates to an apparatus (1) and method for automatically determining the blood flow direction (42) in a blood vessel (14) using the fluorescence light from a fluorophore (16). Blood flow direction (42) is determined by first identifying a blood vessel structure (38) in an input frame (6) from a camera assembly (2) using a pattern recognition module (26). Blood flow direction (42) is determined from the spatial gradient (dI/dx) of the fluorescence intensity (I) along the identified blood vessel structure (38) and the temporal gradient (dI/dt). An output frame (48) is displayed on a display (36) with time-varying marker data (52) overlaid on the identified blood vessels structure (38) and representative of the blood flow direction (42).

Abstract: The present invention relates to a device for the discrimination of biological tissues, such that it is capable of carrying out the discrimination of tissue under complicated operating conditions, for example due to the presence of contaminating elements given off by a cutting operation, due to the presence of moisture in the biological tissue, or due to the presence of a non-controlled atmosphere that interferes with the results of the readings. The invention allows building more complex devices, including cutting instruments, such that it is possible to carry out a surgical intervention in a safe manner by preventing cutting into tissues that are to be avoided during said cutting operation.

Abstract: The present invention relates to a system for vital signs detection. The system comprises a radiation source (16) for emitting radiation in a limited wavelength range for illuminating a skin area of a subject and a radiation detector (12), a radiation detector (12, 30, 40) for detecting radiation reflected from a skin area of a subject (1) in response to said illumination, and for generating first and second detector signals, the first detector signal representing radiation (2) reflected from the skin area of a subject in a first wavelength subrange of said limited wavelength range of radiation (3) and the second detector signal representing radiation in a second wavelength sub-range of said limited wavelength range of radiation different from said first wavelength sub-range, and a vital signs detector (14) for detecting a vital sign from a combination of said first and second detector signals by computing the difference between said first and second detector signals.

Abstract: A method of optimizing sleep of a subject using smart-home devices may include operating a smart-home system that is configured to operate in a normal mode and a sleep mode. The method may also include determining that the smart-home system should transition into the sleep mode. The smart-home devices may use a set of default parameters when operating in the sleep mode. The method may additionally include monitoring, while in the sleep mode, a sleep cycle of the subject using the smart-home devices. The method may further include detecting behavior of the subject that indicates that the sleep cycle of the subject is being interrupted or about to be interrupted, determining an environmental control that corresponds with the behavior of the subject, and adjusting the environmental control using the smart-home devices to prevent or stop the sleep cycle of the subject from being interrupted.

Abstract: An otoscope uses differential reflected response of optical energy at an absorption range and an adjacent wavelength range to determine the presence of water (where the wavelengths are water absorption wavelength and adjacent non-absorption excitation wavelengths). In another example of the invention, the otoscope utilizes OCT in combination with absorption and non-absorption range for bacteria and water.

Abstract: The present disclosure relates to method for predicting location and depth of abnormal tissue in breast tissue by prediction system. The prediction system predicts location based on 2D thermal image generated based on temperature values and intermediate temperature values. The intermediate temperature values are estimated using triangular and rectangular patterns formed on pre-defined model of breast, thermal conductivity of breast tissue, 2D coordinates on one of triangular and rectangular patterns and temperature values at steady state of breast tissue. The depth is predicted based on 3D thermal image of breast tissue generated using temperature values and intermediate temperature values and error parameter.

Abstract: Disclosed is a photoacoustic apparatus including: a photoacoustic probe having a light irradiating unit that irradiates light onto an object and an acoustic wave receiving unit that receives an acoustic wave generated from the object by the irradiation of the light; a specific information acquiring unit that acquires specific information of the object based on the acoustic wave; an order acquiring unit that acquires an order relating to the acquisition of the specific information from an ordering system; an object information acquiring unit that acquires object information relating to the object from an electronic medical record; and a control condition determining unit that determines a control condition of photoacoustic probe based on the order and the object information.

Abstract: Provided are a composition for an acoustic wave probe which includes polysiloxane that has a vinyl group and a phenyl group, polysiloxane that has two or more Si—H groups in a molecular chain, a titanium oxide particle, and a silica particle, in which at least one of the titanium oxide particle (C) or the silica particle (D) is a particle subjected to surface treatment; a silicone resin for an acoustic wave probe; an acoustic wave probe; an acoustic wave measurement apparatus; an ultrasound diagnostic apparatus; an ultrasound probe; a photoacoustic wave measurement apparatus; and an ultrasound endoscope.

Abstract: A method monitors cardiac arrest during physical exercise and consequently activates a rescue request. The method continuously measures a user's heart rate to determine a heart rate in a sequence of predetermined time intervals, by a heart rate measurement device worn by the user; then, generating a signal representative of the heart rate detected in each interval. A motion sensor detects a user's motion condition and generates a motion signal representative of the motion detected. A portable processor receives the heart rate signal and communicates with the heart rate measurement device and with the motion sensor; then processes the signal representative of heart rate, to recognize a possible cardiac arrest condition. The processor processes the motion signal to detect a possible stillness condition. The processor activates a rescue request if both a cardiac arrest condition and a stillness condition have been recognized. A system executes the method.

Abstract: A cardiac analysis system is for use during a cardiac rehabilitation exercise. The system monitors the user's heart rate, activity level and respiration frequency and thresholds are set for these parameters. The system then determines whether or not an exercise being undertaken is suitable for cardiac rehabilitation.

Abstract: A non-invasive system and method for measuring blood pressure variability includes a cuff (20) pneumatically connected to a pump (14) to inflate the cuff to be wrapped around a limb (21) of a subject. A pressure sensor (18) is associated with the cuff for measuring cuff pressure (52). A photoplethysmogram sensor (26) attached to a fingertip in the same limb (21) of the subject and placed distal to the cuff for monitoring blood flow and recording a pulse plethysmograph signal. A control unit (12) connected to the pressure sensor (18) and the photoplethysmogram sensor (26) for simultaneously recording the cuff pressure and the plethysmograph signal such that an empirical relationship is derived between the cuff pressure and an amplitude measure of the plethysmograph signal (54) to measure short-term variation in systolic and diastolic blood pressures at a frequency corresponding to respiratory cycle.

Abstract: A method and system for determining fractional flow reserve (FFR) for a coronary artery stenosis of a patient is disclosed. In one embodiment, medical image data of the patient including the stenosis is received, a set of features for the stenosis is extracted from the medical image data of the patient, and an FFR value for the stenosis is determined based on the extracted set of features using a trained machine-learning based mapping. In another embodiment, a medical image of the patient including the stenosis of interest is received, image patches corresponding to the stenosis of interest and a coronary tree of the patient are detected, an FFR value for the stenosis of interest is determined using a trained deep neural network regressor applied directly to the detected image patches.

Abstract: Systems and methods are disclosed for using patient specific anatomical models and physiological parameters to estimate perfusion of a target tissue to guide diagnosis or treatment of cardiovascular disease. One method includes receiving a patient-specific vessel model and a patent-specific tissue model of a patient anatomy; extracting one or more patient-specific physiological parameters (e.g. blood flow, anatomical characteristics, image characteristics, etc.) from the vessel or tissue models for one or more physiological states of the patient; estimating a characteristic of the perfusion of the patient-specific tissue model (e.g., via a trained machine learning algorithm) using the patient-specific physiological parameters; and outputting the estimated perfusion characteristic to a display.

Abstract: The present disclosure provides for each of a method of characterizing divergence of a monitored flow rate of blood through an implantable blood pump, and a method of predicting an upcoming adverse cardiac event using operating data of the blood pump, such as the characterized divergence data. Predicting an upcoming adverse cardiac event may be further based on similar operating data from a plurality of other implantable blood pumps.

Abstract: A bio-signal measuring apparatus includes an optical sensor including a photodetector and a light source array disposed around the photodetector, a first electrode disposed between the photodetector and the light source array, and a second electrode disposed on an outer periphery of the light source array. The bio-signal measuring apparatus further includes an impedance measurer configured to measure an impedance of an object, using the first electrode and the second electrode, and a processor configured to determine a contact state between the object and the optical sensor, based on the measured impedance.

Abstract: Devices, systems, and methods for pulse wave velocity determination are disclosed. The apparatus includes an intravascular device that can be positioned within a vessel. The intravascular device includes a flexible elongate member having a proximal portion and a distal portion. A pressure sensor can be coupled to the distal portion of the flexible elongate member. The pressure sensor can monitor pressure within the vessel. At least one imaging element can be coupled to the distal portion of the flexible elongate member. The imaging element can monitor the wall thickness of the vessel. A processing system in communication with the intravascular device can control the monitoring of the pressure and the monitoring of the wall thickness of the vessel. The processing system can receive pressure data and wall thickness data and determine a pulse wave velocity of fluid within the vessel.

Abstract: Disclosed is a system that includes pressure sensors to assist in monitoring pressure at a selected location. Pressure sensors may be applied to or incorporated into catheters and/or shunts positioned within a patient. A monitoring system may then receive signals from the pressure sensors to monitor pressure at the location over time.

Abstract: A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Abstract: An information processing device, a biomedical-signal measuring system, and a recording medium storing program code for causing a computer to execute a biomedical signal display method. The information processing device includes circuitry to display, on a display device, a first waveform display area indicating a waveform that indicates changes over time in a biomedical signal, and display a distribution display area indicating a distribution of the biomedical signal. Once input data indicating selection of a certain point of the waveform displayed in the first waveform display area is accepted, the circuitry displays the distribution display area based on the input data when the distribution display area is hidden from view, and the circuitry updates the distribution indicated in the distribution display area before the input data is accepted to a distribution based on the input data and displays the updated distribution when the distribution display area is being displayed.

Abstract: A method of transplanting a desired emotional state from a donor to a recipient, comprising determining an emotional state of the donor; recording neural correlates of the emotional state of the donor who is in the desired emotional state; analyzing neural correlates of the emotional state of the donor to decode at least one of a temporal and a spatial pattern corresponding to the desirable emotional state; converting said at least one of a temporal and a spatial pattern corresponding to the desirable emotional state into a neurostimulation pattern; storing the neurostimulation pattern in the nonvolatile memory; retrieving the neurostimulation pattern from the nonvolatile memory; stimulating the recipient's brain with at least one stimulus modulated with the neurostimulation pattern to induce the desired emotional state in the recipient.

Abstract: An electrical activity monitoring system that includes an sensor sub-system having first and second capacitive electrodes that are configured to electrically couple to a subject's skin and detect electrical signals of a subject, a conductive layer is configured to couple to an anatomical region of the subject and generate an anatomical reference signal, a control module that is programmed to control the sensor sub-system and determine physiological characteristics as a function of signals transmitted from the sensor sub-system.

Abstract: A method includes forming a film, forming a first pattern of two or more vias at least partially through the film, attaching the film to a first support structure, the first support structure comprising an adhesive layer formed over a first carrier, wherein attaching the film to the first support structure comprises bonding a first surface of the film to the adhesive layer of the first support structure, wherein the film is stretchable in at least a first direction along the first surface, and wherein the first carrier maintains the first pattern of vias within a given threshold distortion following a given process conducted after attaching the film to the first support structure.

Abstract: Disclosed herein are a system and a method for volitional electromyography (vEMG) signal detection from an EMG signal when functional electrical stimulation (FES) is applied. The system for vEMG signal detection includes a receiver for receiving data from an EMG electrode when FES is applied, a memory for storing a program for detecting a vEMG signal using the received data, and a processor for executing the program, wherein the processor cuts the data received from the EMG electrode disposed at a predetermined position, calculates a difference between data for previous FES and data for current FES, and detects the vEMG signal using the calculated difference.

Abstract: The disclosed invention includes integrative electrochemical aptamer-based sensors for use in wearable biofluid sensing devices. The disclosed integrative EAB sensors are configured to detect very low concentrations of target analytes in a sweat or biofluid sample by aggregating signals from individual sensing elements over time until a signal threshold is reached. Signal aggregation is accomplished through various retention structures that extend the time sensing elements retain target analyte molecules. Embodiments include attaching complementary primers and functional groups to the aptamer, covering such retention structures with blockers until analyte capture, or coating the sensor electrode with a hydrophilic and hydrophobic monolayer. The invention also includes methods of using the disclosed integrative sensors. Some embodiments of the disclosed method include tracking time to signal threshold to estimate analyte concentration.

Abstract: The exemplified intrinsic phase space tomography methods and systems facilitate the analysis and evaluation of complex, quasi-periodic system by generating computed phase-space tomographic images as a representation of the dynamics of the quasi-periodic cardiac systems. The computed phase-space tomographic images can be presented to a physician to assist in the assessment of presence or non-presence of disease. In some embodiments, the phase space tomographic images are used as input to a trained neural network classifier configured to assess for presence or non-presence of significant coronary artery disease.

Abstract: Provided is a body composition analyzing apparatus by using an impedance of a half of an upper body. According to an example embodiment, the body composition analyzing apparatus includes a first electrode part which comes into contact with a half of an upper body of an object, a second electrode part which comes into contact with the half of the upper body, a measurer configured to apply a current to each of the electrode parts, and to measure an impedance of the half of the upper body of the object by measuring a voltage of each of the electrode parts, and an analyzer configured to analyze body composition of the object based on the measured impedance of the half of the upper body.

Abstract: A powered surgical cutting and stapling instrument is disclosed. The instrument includes at least one sensor to measure at least one parameter associated with the instrument, at least one processor, and a memory operatively associated with the processor. The memory includes machine executable instructions that when executed by the processor cause the processor to monitor the at least one sensor over a predetermined time period and determine a rate of change of the measured parameter.

Abstract: Generally, an animal monitoring device configured as a bolus for oral administration to reside in the reticulorumen of a ruminant animal having a memory element, a processor in communication with the memory element and a computer code contained in the memory element including a power management module executable by the processor to regulate power use by the bolus based on determination of remaining energy stored in an energy source and the determined power requirements over a pre-determined life cycle of the bolus.

Abstract: A micro acetone detecting device is provided. The micro acetone detecting device includes a circuit board, a casing, an acetone sensor and an air pump. The casing has a first through hole and a second through hole. The casing is assembled on the circuit board, and an interior of the casing and the circuit board define an accommodation space. The acetone sensor is disposed in the accommodation space and electrically connected to the circuit board. The air pump is disposed in the accommodation space and electrically connected to the circuit board. When the air pump is actuated to change the pressure of the gas in the accommodation space, the gas flows into the accommodation space through the first through hole, and the gas in the accommodation space is measured by the acetone sensor to obtain an acetone concentration, and then the gas is discharged out through the second through hole.

Abstract: Computers are that include interfaces configured to acquire data indicating a pulse or heartbeat of an animal, and processors configured to determine whether a prescribed condition is satisfied or not based on the data indicating the pulse or the heartbeat of the animal, and calculate a respiratory rate in a period of time for which the prescribed condition is satisfied, are provided.

Abstract: A breath test device capable of correctly and easily performing a diagnosis of COPD in routine checkups, including: a flow path for flowing a respiratory gas of an examinee; an airway member having a pair of detection windows facing each other across the flow path; a gas sensor having a light emitting section that emits an infrared ray to the flow path through one of the detection windows and a light receiving section that receives the infrared ray emitted by the light emitting section through the other detection window; and a mouthpiece connected to the airway member in a state of communicating with the flow path, wherein the airway member and the gas sensor are integrally constituted by mounting the gas sensor on the airway member.

Abstract: Axial stress or similar properties in a stressed connective tissue may be assessed during surgery by excitation of the ligament to create a shear wave allowing measurement of the shear wave velocity which has been identified as having a component related to axial stress.

Abstract: A method includes receiving one or more signals indicative of a position of a distal-end assembly of a medical probe within an organ of a patient. Based on the received signals, an inner volume that is confined within the distal-end assembly is determined. An anatomical map of the organ is updated, to denote the inner volume of the distal-end assembly as belonging to an interior of the organ.

Abstract: A method for estimating a pose of an oral hygiene device including a pattern and a plurality of groups of visual markers relative to a location includes (i) receiving image data reproducible as an image of at least a portion of the oral hygiene device; (ii) analyzing the image data to identify a region of interest within the image; (iii) identifying, using at least one of the one or more processors, all candidate visual markers within the region of interest; (iv) obtaining a first proposed three-dimensional pose of the oral hygiene device; (v) validating the first proposed three-dimensional pose of the oral hygiene device; and (vi) obtaining a second proposed three-dimensional pose of the oral hygiene device based on the validated first proposed three-dimensional pose.

Abstract: Disclosed herein are devices and systems for intraoral visualization. In one aspect, an intraoral visualization system includes at least one intraoral visualization device, each intraoral visualization device comprising: a casing comprising a base and a head; at least one imaging device contained within the head, the at least one imaging device configured to capture video data; a plurality of lighting units contained within the head, each lighting unit comprising a discrete lighting source; a communications module; a power module; and at least one switch in operative communication with and configured to control operation of at least one of: the at least one imaging device or the plurality of lighting units. Also disclosed herein are methods for using the disclosed intraoral visualization devices and systems.

Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the the first and second measurement portions.

Abstract: A surgical image acquisition system includes multiple illumination sources, each source emitting light at a specified wavelength, a light sensor to receive light reflected from a tissue sample illuminated by each of the illumination sources, and a computing system. The computing system may receive data from the light sensor when the tissue sample is illuminated by the illumination sources, and calculate structural data related to one or more characteristics of a structure within the tissue. The structural data may be a surface characteristic such as a surface roughness or a structure composition such as a collagen and elastin composition. The computer system may further transmit the structural data to a smart surgical device. The smart devices may include a smart stapler, a smart RF sealing device, or a smart ultrasonic cutting device. The system may include a controller and computer enabled instructions to accomplish the above.

Abstract: An image acquisition system includes a plurality of illumination sources, each configured to emit light having a specified central wavelength, a first light sensing element having a first field of view and configured to receive illumination reflected from a portion of a surgical site, a second light sensing element having a second field of view and configured to receive illumination reflected from a second portion of the surgical site, and a computing system. The computing system is configured to receive data from the first light sensing element and from the second light sensing element, compute imaging data based on the data received from the first and second light sensing elements, and transmit the imaging data for receipt by a display system. The second field of view may overlap at least a portion of the first field of view. A control system of the image acquisition system may function similarly.

Abstract: A compact perfusion scanner and method of characterizing tissue health status are disclosed that incorporate pressure sensing components in conjunction with the optical sensors to monitor the level of applied pressure on target tissue for precise skin/tissue blood perfusion measurements and oximetry. The systems and methods allow perfusion imaging and perfusion mapping (geometric and temporal), signal processing and pattern recognition, noise cancelling and data fusion of perfusion data, scanner position and pressure readings.

Abstract: A system and method for preparing a diagnostic fluid sample for use with a fluid assay system. The method comprises the steps of: amplifying the fluid sample to increase the number of cells subject to being tested; drawing a first volume of the fluid sample into a first syringe of a dual-barrel syringe and dispensing the first volume of the fluid sample through a media filter. The method further comprises the steps of placing the bacteria-laced filter into a lysis module; dispensing a first portion of a lysis buffer into the lysis module from the second syringe of the dual-barrel syringe; and dispensing a second portion of the lysis buffer through the media filter into a disposable cartridge of a fluid assay system.

Abstract: An apparatus for eliciting a blood sample comprises a housing, an aperture in a wall of the housing, an aperture cover moveable between a first position in which the aperture is covered and a second position in which the aperture is uncovered, the aperture cover comprising a sealing member configured to seal the aperture on a first side of the wall when the aperture cover is in the first position and a user-contactable part extending from the sealing member through the aperture to the second side of the wall and configured to allow a user to move the aperture cover between the first and second positions.