Abstract: A medical image managed by a medical information management system is displayed in a layout region that is displayed on a display of an information terminal, and thumbnail images of similar cases received from a case retrieval system are displayed in a case display region. In the layout region, a display box displaying a thumbnail image of a diagnosis object case and display boxes displaying thumbnail images selected from the thumbnail images displayed in the case display region are displayed adjacent to one another.

Abstract: One embodiment of the present invention provides an apparatus for analyzing substances within a liquid. The apparatus includes an absorber that comprises one or more layers of absorbent material for absorbing the liquid and one or more sensors embedded within the one or more layers of absorbent material. The sensors are configured to provide information associated with the substances included in the absorbed liquid. The apparatus further includes electrical conductive traces coupled to the one or more sensors, thereby facilitating transmission of outputs of the sensors.

Abstract: Provided are an optical switch, an optical probe including the optical switch, and a medical imaging apparatus including the optical probe. The optical probe includes a probe body that is configured to be insertable into a body cavity, and an optical switch that is disposed in the probe body and includes a first region formed of a material having a first refractive index, and a second region that forms an interface with the first region and is configured to have a fluid is introduced into the second region, wherein the optical switch is configured to change a path of propagation of incident light according to a second refractive index of the second region.

Abstract: Disclosed is an optoacoustic probe with a coated transducer assembly. The probe includes a transducer assembly with a multi-layer coating on the active end thereof. The multi-layer coating includes a layer of parylene and at least two layers of metal. In an embodiment, the multi-layer coating includes a layer of nickel, at least one layer of parylene, and a layer of gold.

Abstract: The present invention provides devices and methods for measuring the temperature distribution of an eye using non-invasive techniques. Embodiments of the present invention utilize laser speckle cross-correlation to determine the thermal distribution of an eye.

Abstract: Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT.

Abstract: An implantable pressure sensor device (100) has a housing (10) which is at least partially made of a pressure transmitting membrane (20), and which includes one or more regions which can reversibly deform while maintaining the surface area of the membrane (20) when the internal volume of the housing (10) is changed. The housing (10) has a non-circular cross-section which can deform to a more circular shape when pressure in the internal volume increases. An inner housing is preferably situated within the housing, with its exterior spaced from the interior of the housing, and has its inner volume in fluid communication with the space between the housing and inner housing.

Abstract: The present document describes a system for equalizing the pressure of a pressure guidewire against the pressure of an aortic pressure device: the system comprising two methods of equalizing the pressure against each other, one method that involves a gain adjustment and another method that involves the addition of an offset; the method further comprising a method for detecting which method should be applied to the situation, the detecting methods including: the contribution of the operator; an algorithm detecting the first equalization from subsequent post procedure equalizations, the algorithm including various factors such as incrementing the equalization requests, measuring the elapsed time and others.

Abstract: A blood pressure cuff assembly for an ambulatory blood pressure monitor may include a hollow cuff and an elastic liner provided on the reverse side of the cuff. An airbag may be provided in the cuff. A first connection part and a second connection part may be provided on the cuff. A third connection part and a fourth connection part may be correspondingly provided on the liner. The effect of tight inside and loose outside is achieved by the combination of the elastic liner and the cuff. When worn on an upper arm, the elastic liner has an elastic deformation and consequently tightens around the upper arm so as to realize certain slip resistance, and the cuff will not slip down even tied a bit loosely when located on the upper arm. The feeling of constraint from the cuff is reduced significantly and the comfort is improved.

Abstract: A blood pressure measuring apparatus, which measures a blood pressure of a living body, includes: a cuff-pressure control unit which controls a cuff pressure of a cuff that presses a part of the living body; an oscillation signal detection unit which detects an oscillation signal from the cuff pressure; a blood pressure specification unit which specifies systolic and diastolic blood pressures as the blood pressure of the living body from the oscillation signal; and a blood pressure determination unit which determines whether systolic and diastolic blood pressures are appropriate or not.

Abstract: With the blood pressure meter of the present invention, a pump unit is connected via a first fluid path to a fluid bladder. The first fluid path extends straight in the Z direction between the pump unit and the fluid bladder, sends air supplied from the pump unit to the fluid bladder or sends air inside of the fluid bladder to a valve.

Abstract: The heart rate monitor disclosed herein removes a step rate component from a measured heart rate by using one or more filtering techniques when the step rate is close to the heart rate. In general, a difference between the step rate and the heart rate is determined, and the step rate is filtered from the heart rate based on a function of the difference.

Abstract: A computer readable storage medium configured to cause a system to perform operations of computing the standard deviation of a plurality of K?1 most recent heart beat intervals and a current heart beat interval (I1) from a plurality of consecutive heart beat intervals, from a sum (S1) of K most recent heart beat intervals squared and the sum (S2) of the K most recent heart beat intervals and a Kth oldest heart beat interval (I2). The computer readable storage medium calculates an updated sum (S1?) of S1 minus I2 squared plus I1 squared and the updated sum (S2?) of S2 minus I2 plus I1, and a square root of the sum of the ratio of S1? to K and of the ratio of the square of S2? to the square of K.

Abstract: A photoelectric sensor can include: a lighting element configured to generate a first optical signal, where a second optical signal is generated by reflection of the first optical signal when emitting an object; a driving circuit configured to drive the lighting element; a photoelectric conversion circuit configured to generate a first optical current in accordance with the second optical signal; and a programmable current amplifier circuit configured to sample and hold the first optical current when the lighting element is in operation, and to generate a second optical current when the lighting element is out of operation in one detection period, where the second optical current lasts for at least one working period in the detection period, and where the second optical current represents the first optical current.

Abstract: An apparatus and a method for detecting bio-information are provided. The apparatus includes a bio-signal detector including a light emitter including a light-emitting diode (LED) and a laser diode (LD), the LED and the LD being configured to emit optical signals on an object. The bio-signal detector further includes an optical detector including a light-receiver configured to detect optical signals modulated by the object. The apparatus further includes a processor configured to process the optical signals to detect the bio-information of the object.

Abstract: A conversion circuit for converting a current signal into a first output voltage signal, where the current signal flows through a sensing component, is provided. The conversion circuit includes: a first current eliminating circuit, configured to eliminate a first current in the current signal. The first current eliminating circuit includes: a current sample and hold circuit; and a current driving circuit, coupled between the sensing component and the current sample and hold circuit; a second current eliminating circuit, coupled to the sensing component and configured to eliminate a second current in the current signal; and an integrating circuit, coupled to the sensing component and configured to integrate a third current in the current signal, and output a first input voltage signal between a first integration output terminal and a second integration output terminal.

Abstract: The invention refers to a method of determining an indicator that is representative for a patient's volume responsiveness, comprising the following steps: (i) measuring a sequence of pulse signals of a patient; (ii) determining an envelope(signal)-curve based on the sequence of measured pulse signals; (iii) determining a fit(envelope(signal))-function based on the previously determined envelope(signal)-curve, the fit(envelope(signal))-function representing an idealized curve progression of the envelope(signal)-curve without comprising pulse variations caused by ventilation or respiration induced heart-lung interaction; (iv) determining respiratory pulse variation signals corresponding to the pulse variations caused by ventilation or respiration induced heart-lung interaction; (v) determining an envelope(respiration)-curve based on the previously determined respiratory pulse variation signals; (vi) determining a fit(envelope(respiration))-function based on the previously determined envelope(respiration)-curve,

Abstract: A manometric probe, comprising: a main body (2) provided with a longitudinal axis (X); an extensible membrane (3) sealingly associated to at least two annular areas of the main body (2) so as to delimit a chamber (4) external to the main body (2); feed means (51,52) arranged so as to enable feeding of a fluid inside the chamber (4).

Abstract: A computerized method comprises statistically analyzing, using one or more processors, at least one section of a digitally recorded electroencephalography (EEG) signal that comprises an arousal segment to determine, for the arousal segment, at least one of amplitude and power at different frequencies as a function of time; selecting specified features from the results of the analysis and normalizing the selected features; and assigning, using one or more processors, an intensity scale value to the arousal segment based on the normalized selected features and a reference data set, the reference data set comprising normalized features corresponding to the normalized selected features and being generated based on a plurality of EEG signals comprising arousal segments to which intensity scale values have been assigned based on a visual inspection of the EEG signals.

Abstract: Previous research has shown that the risk of sudden death due to cardiac arrhythmias can be predicted by observing the shape of recorded endocardial electrograms in response to pacing, and in particularly detecting certain small deflections in the recorded electrogram following early stimulation of the heart. A long standing problem has been the reliable detection of these small individual potentials because of the presence of noise in the recorded electrical signals created by other electrical equipment within a typical catheter laboratory. The solution described involves deriving a model of noise from a first portion of the electrogram in which a physiological signal is presumed to be absent, and transforming a second portion of the electrogram, presumed to contain a physiological signal, into the model of noise. The physiological signal can then be identified by identifying portions of signal within the second portion of the electrogram that do not conform to the model of noise.

Abstract: The present invention provides a medical electrode, which comprises an annular adhesive pad (203) to be attached to a living being, a conductive pad (205) disposed in the central hole (207) of the annular adhesive pad, a first conductive snap element (209), a conductive element (211) and a sealing film (213). The conductive element (211) is configured to establish electrical communication between the conductive pad (205) and the first conductive snap element (209) and the sealing film (213) is attached to the annular adhesive pad (203) and to fix at least a portion of the conductive element (211) between the annular adhesive pad (203) and the sealing film (213). The flexibility and/or length of the conductive element is chosen to be large enough so as to allow the first conductive snap element (209) to move without causing the conductive pad (205) to move, resulting in reliable electrical contact between the conductive pad and the skin of the living being.

Abstract: A method and an apparatus for electrophysiology catheter scheme configuration are disclosed. The method includes providing an interactive image of a heart to a user and receiving a user input of a type of catheter and a number of electrodes corresponding to the catheter. A pictorial representation of the catheter positioned inside the interactive image of the heart is generated according to the type of catheter. A pictorial representation of the electrodes as markers on the pictorial representation of the catheter is generated depending on the number of electrodes. Slot numbers of a catheter input pod are mapped to the corresponding electrodes of the catheter that are to be connected to the catheter input pod depending on the type of catheter. Intracardiac electrogram (ICEG) signal labels are assigned depending on the type of catheter, and the ICEG signal labels are marked on the interactive image of the heart to create the electrophysiology catheter scheme.

Abstract: Intracardiac electrograms are recorded using a multi-electrode catheter and respective annotations established. Within a time window a pattern comprising a monotonically increasing local activation time sequence from a set of electrograms from neighboring electrodes is detected. The set is reordered and displayed for the operator.

Abstract: A method of mapping cardiac restitution includes: receiving a plurality of EP data points including location and restitution data; identifying a subset of the EP data points forming an EP data point cluster; fitting a restitution curve to the restitution data of the EP data points forming the cluster; and identifying at least one restitution metric for a region of the cardiac surface corresponding to the cluster from the restitution curve. The restitution curve can be an exponential function using quiescent interval data (e.g., DI and/or CL) as the independent variable and cardiac repolarization activity data (e.g., APD, ARI, and/or EGM width) as the dependent variable. The parameters of the exponential function can be determined by optimizing a cost function. A graphical representation of the restitution metric can also be output on a three-dimensional model of the cardiac surface.

Abstract: A method for positioning an endovascular device in or near the heart using electrocardiogram (ECG) signals. The method includes receiving an endovascular ECG signal including a plurality of waveforms, processing the endovascular ECG signal to calculate a P-wave amplitude and a spectral power for each predetermined time period, determining a maximum P-wave amplitude and an associated maximum spectral power, associating the maximum P-wave amplitude and the maximum spectral power with a predetermined location in or near the heart, calculating a location based on a ratio of the P-wave amplitude to the maximum P-wave amplitude and a ratio of the spectral power to the maximum spectral power, and displaying the location to a user.

Abstract: The difference between the current value and the last value of an RR interval is compared with a predetermined reference differential value, and an attenuation time constant of a peak-hold section is controlled according to the comparison result.

Abstract: Computational models and methods and systems of using the model to estimate variable time delay in the sensorimotor system of a subject are provided. The computational model can estimate variable time delays in the sensorimotor system, predict sensory states based on delayed sensory feedback, and/or control the system in real time. The subject can be a human or a primate. Simulation experiments can show how the model can explain a sensorimotor system's ability to compensate for delays during online learning and control.

Abstract: Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveforms over large brain surface areas by any of the devices disclosed herein.

Abstract: An FPC compartment in a left rim is slit-shaped. A left FPC positioning member supports a flexible printed circuit (FPC) in the FPC compartment such that a main surface of the FPC extends substantially horizontally. The FPC supported in the FPC compartment is twisted by substantially 90° at an entrance to a left hinge. The FPC extends around a hinge pin and is received in a left electronic-component compartment. The FPC is held in the left electronic-component compartment such that the main surface of the FPC extends substantially vertically. A left end piece located adjacent to the left hinge has a left cavity accommodating a left deformable bend of the FPC.

Abstract: An evoked potential monitoring system including a control unit having stimulator circuitry and a probe assembly coupled to the control unit. The probe assembly includes a stimulus probe and a stimulator handpiece selectively coupled to the stimulus probe. The handpiece includes a handle, control circuitry, and a switch. The control circuitry is electrically coupled to the stimulator circuitry. The switch is electrically coupled to the control circuitry and extends to an exterior portion of the handle. In this regard, movement of the switch remotely controls the stimulator circuitry to continuously increment or decrement a stimulation energy level delivered to the stimulus probe over a series of discrete, incremental steps.

Abstract: The disclosure describes an apparatus for testing the integrity of mammary tissues comprising one or more transmission antennas configured to strike a mammary tissue with a main electromagnetic field in the microwave frequency band, one or more reception antennas configured to pick up a corresponding reflected electromagnetic field, a processing unit comprising a first operating module configured to determine a main parameter representing an electrical discontinuity of the mammary tissue, and a second operating module configured to generate a signal representing a non-integrity of the mammary tissue.

Abstract: Methods and system for performing magnetic induction tomography imaging of an object are provided. An apparatus includes an array of unit cells and a control circuit coupled to the array of unit cells. The array of unit cells can generate a first magnetic field using an excitation pattern in the direction of a target object and sense a second magnetic field induced in the target object by the first magnetic field. The control circuit can determine a minimum of the first magnetic field. The minimum may correspond to a higher conductivity region of the target object. The control circuit can adjust the excitation pattern based on the higher conductivity region of the target object.

Abstract: In a method, a local coil, and an apparatus for magnetic resonance imaging, an examination subject is situated in a patient receiving area of the apparatus, together with at least one marker element. The apparatus is operated to perform a radio-frequency excitation of the at least one marker element, and to read out magnetic resonance signals that are emitted by the at least one marker element. An image data acquisition scanner of the magnetic resonance apparatus is adjusted using the magnetic resonance signals that have been read out. Magnetic resonance image data are acquired from the subject by operation of the adjusted image data acquisition scanner.

Abstract: A strap-fastening apparatus for fastening safety straps is provided, wherein the strap-fastening apparatus has at least one fastening rail and at least one fastening clip. The at least one fastening clip has a strap-fastening element and the strap-fastening element, in a state of the at least one fastening clip arranged with the at least one fastening rail, is arranged within the at least one fastening rail.

Abstract: A device for taking a measurement of a dimension of a part of the body of a patient, includes: an electronic tape measure having a portable housing, a winder accommodated in the housing, a tape which is partially wound on the winder and of which a portion, called the “unwound portion”, extends outside the housing, and a measuring module for a measurement, relative to the unwound portion; a consistency control module for checking the consistency of the measurement by at least one consistency rule and at least one context datum; and an alert module for delivering an alert if an inconsistency is detected by the consistency control module.

Abstract: The present invention is a system and method to collect and analyze data produced through biometric and psychometric tasks on interactive computing devices. The collected biometric data can be used to quantify motor skills and to generate statistics that correlate with or predict ability in other functional domains. The biometric data tasks and data collection can be incidental to user interaction with a computing device using a touchpad or other input device—such as users drawing lines to connecting screen elements while using the user interface of an application on a computing device.

Abstract: A method for an assessment of a movement of a limb-related point in a predetermined 3D space effected by a user displacing the limb in the 3D space is provided. The method includes the steps of providing display surfaces in the 3D space around the user, providing a limb position point connected to a portion of the user's limb associated to the limb-related point, and providing sensors to detect the limb position point in the 3D space in relation to the joint. A computer program calculates a direction defined by a straight line between the joint and the limb-related point and provides a representation of the position of the limb-related point in the 3D space as a function of a distance between the joint and the limb-related point on one of the display surfaces on the line.

Abstract: Methods of exerting magnetic forces to collect and manipulate magnetic particles disposed in a portion of subsurface vasculature using a wearable device are provided. The wearable device is configured to change the exerted magnetic force over time. For example, the exerted magnetic force could be sufficient to collect the magnetic particles during a first period of time and low enough to release the magnetic particles during a second period of time. The exerted magnetic force could be changed over time to vary some effect on the magnetic particles, for example to control a rate of release of collected magnetic particles. In some embodiments, the magnetic particles are configured to bind to an analyte of interest. The collection and manipulation of the magnetic particles can enable detection of one or more properties of the analyte, modification of the analyte, and/or extraction of the analyte bound to the magnetic particles.

Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract: Method and apparatus for determining and outputting projected alarms or notifications associated with anticipated hyperglycemic or hypoglycemic conditions are provided. Systems and kits employing the devices described herein executing the one or more routines described are also provided.

Abstract: Near-infrared spectroscopy (NIRS) is used to measure parameters such as pH of muscle tissue of a patient that is affected by a cardiac arrest. Analysis of the pH and other parameters such as SmO2 facilitates distinguishing between an arrhythmia arrest and an asphyxia arrest.

Abstract: The invention relates to a dialysis machine having the capability of determining a predialytic property in the blood of a dialysis patient which has an extracorporeal blood circuit, a dialyzate circuit, a dialyzer and a processing unit, wherein at least one sensor for determining a property of the dialyzate is arranged in the dialyzate circuit. The processing unit is configured such that temporal evaluation ranges are fixed during an initial phase of the dialysis treatment, in which temporal evaluation ranges all stability criteria from a predefined group are satisfied; and in that only measured values determined by the at least one sensor within these temporal evaluation ranges are used for determining a predialytic property of the patient's blood.

Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.

Abstract: An apparatus for eliciting a blood sample is presented having a lancet for lancing a body part of a user and a cleaning member of absorbent material operable to clean a surface of the body part, the apparatus being configured such that in use the lancet is moved to lance a body part of a user and subsequently the cleaning member is moved to contact the body part of the user so as to remove blood from the surface of the body part prior to collection of the blood sample from the surface of the body part.

Abstract: A needle assembly is disclosed. The needle assembly includes a housing having a flash chamber, and having a distal end and a proximal end engageable with a specimen collection container. The assembly includes a cannula having a patient end, a non-patient end, and a sidewall extending therebetween defining a cannula interior. The patient end of the cannula projects at least partially from the distal end of the housing, and the cannula interior is in fluid communication with the flash chamber. The assembly further includes a shield restrainably engaged with a portion of the housing and axially transitionable over the patient cannula from a retracted position in which the patient end is exposed, to an extended position in which the patient end is shielded by at least a portion of the shield, wherein at least a portion of the flash chamber is visible in the retracted position.

Abstract: A system for detecting an incontinence event includes a pad which is deployable on a mattress and which, as deployed, has an open circuit comprised of a first conductor extending from a first terminal of an RFID inlay, and a second conductor extending from a second terminal of the RFID inlay. The system also includes an RFID reader subsystem having an array of two or more spatially distributed antennas. The detection system commands spatially and temporally varying transmission of energy from the antenna array at a variety of powers and frequency settings. The detection system monitors the antenna array for a return signal resulting from the transmission. The return signal has a moisture status indicator which indicates whether or not liquid is present on the pad. The detection system also causes communication of a WET or DRY status to a destination. The reported WET or DRY status depends on the moisture status indicator.

Abstract: A method for identifying changes in an epilepsy patient's disease state, comprising: receiving at least one body data stream; determining at least one body index from the at least one body data stream; detecting a plurality of seizure events from the at least one body index; determining at least one seizure metric value for each seizure event; performing a first classification analysis of the plurality of seizure events from the at least one seizure metric value; detecting at least one additional seizure event from the at least one determined index; determining at least one seizure metric value for each additional seizure event, performing a second classification analysis of the plurality of seizure events and the at least one additional seizure event based upon the at least one seizure metric value; comparing the results of the first classification analysis and the second classification analysis; and performing a further action.