Abstract: A system and method for medical premonitory event estimation includes one or more processors to perform operations comprising: acquiring a first set of physiological information of a subject, and a second set of physiological information of the subject received during a second period of time; calculating first and second risk scores associated with estimating a risk of a potential cardiac arrhythmia event for the subject based on applying the first and second sets of physiological information to one or more machine learning classifier models, providing at least the first and second risk scores associated with the potential cardiac arrhythmia event as a time changing series of risk scores, and classifying the first and second risk scores associated with estimating the risk of the potential cardiac arrhythmia event for the subject based on the one or more thresholds.

Abstract: Medical devices, software and methods are provided, for making a decision as to whether to pause patient chest compression treatment in connection with administering electric shock therapy to the patient. The decision is made depending whether signal spikes identified in the ECG data are determined to be QRS complexes, or merely likely impulsive artifact caused by the chest compressions.

Abstract: Provided is an electrode sheet allowing easy connection of a wiring that is extended, when required, to a measurement position on a living body. The electrode sheet (main sheet (1), auxiliary sheet (10)) includes a sheet-shaped flexible substrate (2, 11), wirings (3, 12) formed on the flexible substrate (2, 11), electrodes (5, 14) formed on the flexible substrate (2, 11) and electrically connected to the wirings (3, 12), and an insulating layer (4, 13) laid on the flexible substrate (2, 11) in such a manner that the wirings (3, 12) are overlaid with the insulating layer (4, 13) while the electrodes (5, 14) are exposed. The electrodes (5, 14) are formed of a conductive material in which conductive particles are dispersed in a thermoplastic resin.

Abstract: The present disclosure pertains to a system configured to deliver sensory stimulation to a user to enhance a target cognitive domain during a sleep session. Example target cognitive domains include memory consolidation, vigilance, verbal fluency, sleepiness, and/or other target cognitive domains. The stimulation is adjusted based on the target cognitive domain to be enhanced. Responsive to one or more brain activity parameters indicating the user is in sufficiently deep sleep, the system is configured to cause one or more sensory stimulators to provide sensory stimulation to the user according to a stimulation strategy associated with the target cognitive domain. The system is configured to determine the effect of the sensory stimulation provided to the user using a quantification method associated with the stimulation strategy and the target cognitive domain. The system includes one or more sensory stimulators, one or more sensors, one or more hardware processors, and/or other components.

Abstract: Example apparatuses, systems, and methods for detecting a muscle tissue ischemia event are provided. An example apparatus may include an electromyography (EMG) sensor applied to the patient to detect electrical activity in the muscle tissue. The apparatus may also include processing circuitry in communication with the EMG sensor and configured to receive EMG signals from the EMG sensor and detect characteristics within the EMG signals indicating oxygen depletion within the muscle tissue of the patient. The characteristics may include a signal power level of the EMG signals increasing by at least a threshold value at a select frequency or with respect to a select band of frequencies. The processing circuitry may be further configured to trigger an output, in response to detecting the characteristics, indicating that the oxygen depletion in the muscle tissue is indicative of an ischemia event.

Abstract: A system for providing information about a patient's heart includes one or more electrodes that receive signals from electrical activity of the heart over one or more heart beat cycles. The system is characterized by an electronic processor coupled to the one or more electrodes to: receive the signals from the one or more electrodes; execute an automated set-up routine that processes the signals to automatically provide at least some set-up results for new mapping configurations; and/or process the signals with beat detection and beat acceptance criteria for new or existing mapping configurations to provide information about how well the signals match one or more of the new or existing mapping configurations.

Abstract: Techniques are disclosed for detecting knowledge based on brainwave response to external stimulation. A subject can be exposed to stimuli and brainwave responses indicating a p-300 signal can be detected. Further stimuli or sequences of stimuli can be selected be presented to the subject based on the category correlated with the stimuli that indicate a p-300 response.

Abstract: Devices and methods are disclosed which relate to the detection of cardiovascular efficiency and risk of disease. The rate of volumetric change of the heart can be determined by measuring the parallel conductance across electrodes attached to the heart. Measurements from a lumen would consider the total conductance. The rate of volumetric or lumen cross-section area change can then be compared to an average model to determine the health of a patient.

Abstract: One embodiment of the present application sets forth a method for predicting recurrence of cancerous cells in a patient that includes measuring, by a first subset of electrodes included in an electrode array operating at a first frequency, a first impedance of a first section of a first sample of tissue excised from the patient, computing a first Cole relaxation frequency for the first section of the first sample based on the first impedance, and generating a first prediction relating to cancerous cells in the patient based at least in part on the first Cole relaxation frequency.

Abstract: An impedance chip detection system for biological testing includes a sensor and a portable detector. The sensor includes an absorbing layer, a sensing layer, and a transmitting layer, and the detector includes a detection slot, a control module provided for an impedance measurement and calculation of a specimen, and a display module for displaying a detection result of the specimen, so that after the sensor is plugged into the detection slot, the sensor performs an impedance measurement and calculation of the specimen and the detector displays the detection result.

Abstract: A magnetic resonance imaging apparatus includes a magnet assembly; a base disposed adjacent to the magnet assembly; a seating member on which an object is to be seated and configured to be rotatably disposed on the base; and an elastic assembly configured to elastically support the seating member on the base to compensate for a load of the object. The elastic assembly includes: an elastic unit having a first end connected to the seating member and configured to generate an elastic force; and a control device disposed on the base and configured to guide a second end opposite to the first end of the elastic unit to adjust an angle between the seating member and the elastic unit.

Abstract: An imaging compatible device for applying a plurality of different loads to a foot for evaluating the Lisfranc joint of a patient is configured to move the ball of the foot in an axial direction, a lateral direction, and a torsional direction to assess a state of the Lisfranc joint.

Abstract: Disclosed are a detection device and a detection method for recognition of a location of an affected part. The detection device includes: a clip (100) attached to an affected part through an endoscopic tool and including an electronic marker (110); and a probe (200) including a measurement unit (210) configured to recognize the electronic marker (110) and which approaches the affected part from an outside of the affected part.

Abstract: The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device.

Abstract: A wearable monitoring system and associated method that is configured to (i) determine three dimensional displacement of the spine of a subject's chest wall with respect to the subject's spine, (ii) process the three dimensional anatomical data, (iii) determine at least one respiratory parameter associated with the monitored subject and value thereof as a function of the three dimensional anatomical data, and (iv) determine a respiratory disorder as a function of the determined respiratory parameter and value thereof.

Abstract: A wearable respiration monitoring system having a transmitter coil that is adapted to generate and transmit multi-frequency AC magnetic fields and a plurality of receiving coils adapted to detect variable strengths in the AC magnetic fields and generate AC magnetic field strength signals representing anatomical displacements of a monitored subject. The wearable monitoring system further having an electronics module that is adapted to receive the AC magnetic field strength signals and determine at least one respiratory disorder associated with the monitored subject as a function of the AC magnetic field strength signals.

Abstract: The health-monitoring system includes one or more cameras which collect graphic data and a controller which calculates body proportion measurements based on the graphic data. Specifically, the health-monitoring system measures a user's body parts and their relative positions. These measurements may be combined with those collected by other devices and sensors within the system which conduct other health-related measurements. The other devices and sensors may be housed within a container and a least one of the cameras may also be housed within the container. In some embodiments, the container is a fixture, such as a bathroom medicine cabinet . The camera may be invisible to a user as positioned within the fixture. Consequently, the user may move and behave normally without changes which may occur due to being self-conscious of the camera. Calculations may occur within the controller or on a remote server to which data is transmitted.

Abstract: A wearable patient monitoring device in a patient monitoring system includes motion sensors generating sensor output signals in response to sensed patient motion, and a processor that processes the sensor output signals according to a template-matching monitoring process that includes (1) detecting occurrence of a first event of a multi-event movement based on first values of the sensor output signals, the multi-event movement having a finite-state-machine (FSM) representation as a sequence of states corresponding to events and expected values of the sensor output signals of the multi-event movement, (2) detecting occurrence of remaining events of the multi-event movement based on a sequence of subsequent values of the sensor output signals, and (3) upon detecting a last event of the multi-event movement, generating an output signal indicating detection of the patient performing the multi-event movement.

Abstract: A method of predicting daily living activities performance of a person with disabilities includes establishing a rehabilitation assessments panel based on a plurality of rehabilitation evaluation scales and laboratory data; evaluating a plurality of persons with disabilities by the rehabilitation assessments panel; entering assessment results and the corresponding activities of daily living (ADL) performance into a machine learning platform; utilizing variable selection methods to select a plurality of variables having optimal classification performance from the rehabilitation assessments panel; executing a machine learning algorithm to create an ADL prediction model based on the selected variables; evaluating a participant in terms of the rehabilitation assessments panel; and entering assessment results into the ADL prediction model for calculation, thereby obtaining a prediction result of future ADL performance for the participant.

Abstract: An action recognition system is illustrated. The action recognition system has an annular body, at least one light emitting unit, at least one light sensing unit and an action recognition module. The annular body is worn on a movable part of a user. One end of the light emitting unit is exposed on an inner side of the annular body, wherein the light emitting unit emits a first light beam illuminating at least a portion of the movable part. One end of the light sensing unit is exposed on the inner side of the annular body. The light sensing unit operatively senses a second light beam reflected by the at least portion of the movable part and generates a light sensing signal. The action recognition module is configured to operatively determine an action of the user according to the light sensing signal.

Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.

Abstract: Sensing and infusion devices are described. In one embodiment, a sensing and infusion device may include an implantable segment having a sensor. The sensing and infusion device may also include a catheter, and a sensor channel may be formed in the catheter. The sensor channel may be configured to retain at least a portion of the implantable segment.

Abstract: [Object] To provide an enzyme sensor and an electronic device that can more accurately measure the amount of the enzyme contained in the body fluid of the subject. [Solution] An enzyme sensor including: a pair of electrodes; an electron transfer layer held between the pair of electrodes; and an electron generating capsule in which a membrane containing at least a substrate of an enzyme to be detected encloses at least one or more kinds of enzymes other than the enzyme to be detected, the electron generating capsule being in contact with the electron transfer layer.

Abstract: Provided are methods and apparatus for receiving sensor data from an analyte sensor of a sensor monitoring system, processing the received sensor data with time corresponding calibration data, outputting the processed sensor data, detecting one or more adverse conditions associated with the sensor monitoring system, disabling the output of the sensor data during the adverse condition time period, determining that the one or more detected adverse conditions is no longer present in the sensor monitoring system, retrieving the sensor data during the adverse condition time period, processing the retrieved sensor data during the adverse condition time period, and outputting the processed retrieved sensor data.

Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

Abstract: Sleeves and cases for protecting medical devices against contamination, and methods for cleaning and disinfecting medical devices are provided. The various embodiments enable a single medical device to be used by more than one patient successively while reducing the risk of disease transmission from patient to patient.

Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.

Abstract: The present invention provides devices and methods for calculating and monitoring oxygenation parameters during treatment with delivery of nitric oxide. The devices and methods of the present invention can calculate the oxygenation index based on measurements of mean airway pressure, saturation of oxygen and fraction of inspired oxygen derived from components of the present invention. Also described is a nitric oxide delivery device that incorporates a proximal pressure transducer.

Abstract: A system that incorporates teachings of the present disclosure may include, for example, an avatar engine having a controller to retrieve a user profile of a user, present the user an avatar having characteristics that correlate to the user profile, detect one or more responses of the user during a communication exchange between the user and the avatar, identify from the one or more responses a need to determine a medical status of the user, establish communications with a medical diagnostic system, receive physiological information associated with the user, submit the physiological information to the medical diagnostic system, receive from the medical diagnostic system a diagnostic analysis of the physiological information, and present the diagnostic analysis to at least one of the user and a medical agent of the user, wherein the user is presented the diagnostic analysis by way of the avatar. Other embodiments are disclosed.

Abstract: A pulse oximetry sensor includes reusable and disposable elements. To assemble the sensor, members of the reusable element are mated with assembly mechanisms of the disposable element. The assembled sensor provides independent movement between the reusable and disposable elements.

Abstract: A device for obtaining a biological sample, such as a capillary blood collection device, that has the ability to lance and squeeze the finger, collect the sample, stabilize the sample, and subsequently dispense the sample in a controlled manner is disclosed. The device also simplifies and streamlines the capillary blood collection by eliminating workflow variabilities which are typically associated with low sample quality including hemolysis and micro-clots.

Abstract: A physical and cognitive field-testing apparatus has a substantially planar touchscreen display on one surface, facing on one direction, and a second display facing in an opposite direction, Internet communication functionality with at least one Internet-based computerized server, a local processor and on-board digital memory, and first software executing on the local processor, an interactive window displayed on the touchscreen display as a result of the display data, comprising at least two graphic artifacts, visually associated with at least a balancing test and a coordination test, an accelerometer installed on the portable computerized appliance, at least two graphic artifacts, at least one of which is associated with the accelerometer.

Abstract: A monitoring system for persons at suicidal risk, the monitoring system includes a wireless network; a central monitoring station, having a computing device with a display; and a monitoring portal to receive information, the monitoring portal having an alarm to provide an alert based on the information received; a wristband having a unique identifier assigned via the central monitoring station; a control center having a power source and a transceiver to wirelessly communicate with the central monitoring station; a GPS tracking device to provide location information to the central monitoring station; a vital sensor integrally incorporated into the wristband to determine a vital sign; and a lock to secure the wristband to the person, the lock being associated with a key; the alarm function is programmed to provide the alert based on the vital sign hitting a predetermined value.

Abstract: A cognitive support system is disclosed. The system includes a data collection subsystem to obtain personal data and contextual data related to the sufferer, from conversations of one or more family members, one or more close friends and one or more co-workers. The system includes a cognitive modelling subsystem to analyse the personal data and the contextual data to build a personalized support model. The system includes a cognitive support subsystem to learn one or more patterns from the personal data and the contextual data based on the personalized support model, verify one or more learnt patterns based on the personal data and the contextual data gathered from the conversations, identify one or more instances of cognitive dysfunction based on the one or more learnt patterns and a current personal data of the sufferer and generate an intervention for the sufferer upon identifying one or more instances of cognitive dysfunction.

Abstract: A method for evaluating a gastrointestinal tract may include receiving an electrical signal that includes data pertaining to motility in the gastrointestinal tract of a patient and analyzing one or more characteristics of the electrical signal relative to one or more respective thresholds indicative of an occurrence or an imminence of a condition of the gastrointestinal tract.

Abstract: The present invention relates to a system device and method for monitoring infant oral motor kinetics (OMK), which can be used to assess the functional significance of the different sucking components, i.e., the plasticity of infant sucking skills in relation to their oral feeding performance, at a particular time, during the developmental period and/or during preventive or therapeutic intervention programs. It is a unique system and apparatus that provides a means to study the nonnutritive and/or nutritive sucking skills, i.e., the Suction and/or Expression components of sucking, of infants in the natural setting, i.e., during a normal feeding session.

Abstract: A system for monitoring the fetal size of an expectant mother comprises an acoustic sensor for positioning over the belly of the expectant mother, the acoustic sensor configured to receive an acoustic signal generated by the fetal heartbeat and to generate a sensor output signal. A fetal size is determined from a sensor output signal strength. This system is based on the realization that certain acoustic signals generated by the fetal heart beat are strongly correlated with the fetus size.

Abstract: The present disclosure relates to a method for determining a user-specific hair treatment with determination and inclusion of the degree of damage of the hair. To this end, the content of cysteic acid is firstly determined with the aid of near-infrared and/or infrared spectra of the keratin fibres of an individual and a degree of damage is derived via a calibration model. Individual treatment advice is output on the basis of the determined degree of damage.

Abstract: Stands for measuring proprioception comprising a hand layer comprising one or more vertically offset portions configured to ensure proper placement of a patient's hand in a predetermined position, a top cover coupled to the hand layer, wherein the top cover is designed to obscure the patient's view of the patient's hand, and a support element coupled to the hand layer and configured to support the hand layer at a predetermined angle are disclosed. Methods for measuring proprioception are also disclosed.

Abstract: Evaluating Electroencephalogram (EEG) data includes receiving initial EEG signals for a patient being subjected to an anesthetic agent to minimize a response to surgical stimulation; based on a similarity between the initial EEC signals and a corpus of historical EEG signals, identifying a reference series of EEG signals, wherein the reference series of EEG signals comprises a time-ordered sequence of expected EEG signals for the patient; receiving a subsequent EEG signal for the patient after a change to a level of the anesthetic agent has occurred; and displaying a difference between the subsequent EEG signal and a one of the expected EEG signals, wherein the difference is indicative of a probability that the patient will respond to surgical stimulation.

Abstract: A medical monitoring device includes a signal collection module, a data processing module and a display module. The data processing module processes a vital sign signal collected by the signal collection module, generates physiological parameters, and generates visualization information about parameters of interest corresponding to a designated anesthetic phase based on request information, the designated anesthetic phase is an anesthetic induction phase, an anesthetic maintenance phase or a postoperative recovery phase, and the parameters of interest comprise parameters selected from the physiological parameters and/or anesthetic parameters derived from the physiological parameters. The display module at least displays the visualization information about the parameters of interest corresponding to the designated anesthetic phase in an anesthetic state display area.

Abstract: An alertness prediction bio-mathematical model for use in devices such as a wearable device that improves upon previous models of predicting fatigue and alertness by gathering data from the individual being monitored to create a more accurate estimation of alertness levels. The bio-mathematical model may be a two-process algorithm which incorporates a sleep-wake homeostasis aspect and a circadian rhythm aspect. The sleep-wake homeostasis aspect of the model is improved by using actigraphy measures in conjunction with distal skin, ambient light and heart rate measures to improve the accuracy of the sleep and wake estimations. The circadian rhythm model aspect improves fatigue prediction and estimation by using distal skin, heart rate and actigraphy data, The sleep-wake homeostasis and circadian rhythm aspects may also be combined with additional objective and subjective measures as well as information from a user to improve the accuracy of the alertness estimation even further.

Abstract: Example systems, methods, and apparatus, including cognitive platforms, are provided for computing performance metrics of an individual based at least in part on user interaction(s) with computerized tasks and/or interference and at least one physiological measure of the individual, where the performance metric provides an indication of the cognitive abilities of the individual. The apparatus can be coupled to at least one physiological component to perform the physiological measurement of the individual. The apparatus also can be configured to adapt the tasks and/or interferences to enhance the individual's cognitive abilities.

Abstract: A system includes a millimeter-wave radar sensor disposed on a circuit board, a plurality of antennas coupled to the millimeter-wave radar sensor and disposed on the circuit board, and a processing circuit coupled to the millimeter-wave radar sensor and disposed on the circuit board. The processing circuit is configured to determine vital signal information based on output from the millimeter-wave radar sensor.

Abstract: A system includes a housing, a capacitive sensor, and an electronics module. The housing has an interior and is configured to be maintained at a first pressure that is lower than a pressure external of the housing the interior under a vacuum pressure. The capacitive sensor is disposed within the housing and includes a plurality of layers of a dielectric material. The electronics module is coupled to the capacitive sensor and includes a processor configured to receive a raw capacitance value from the capacitive sensor and to output a signal identifying a pressure exerted on the capacitive sensor.

Abstract: A vital signs monitoring system, the system including: (a) an ear device including: a curved body adapted to a shape of an ear, an upper end, a lower end, two opposite facing sides, a first side adapted to be proximal a skull and a second side adapted to be proximal an earlobe, the ear device including: (i) a temperature sensor adapted to sense a body temperature from a depression between a lower, jawbone and skull; and (b) a control system, including a processor and a memory, configured and operable to control operation of the ear device, to collect signals received from at least one sensor including the temperature sensor, to process the signals to provide medically significant results.

Abstract: The invention provides a physiological probe that comfortably attaches to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe, which comprises a separate cradle module and sensor module, secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. The cradle module, which contains elements subject to wear, is preferably provided as a disposable unit.

Abstract: A medical device includes a hub and an adhesive patch coupled to the hub. The adhesive patch is to couple the hub to an anatomy. The adhesive patch defines an edge that extends along a perimeter of the adhesive patch. The medical device includes an anisotropic shim coupled to the adhesive patch along the perimeter of the adhesive patch proximate the edge to resist an uncoupling of the adhesive patch from the anatomy. The shim has an inner periphery spaced apart from an outer periphery and the shim is locally rigid between the inner periphery and the outer periphery.

Abstract: A physiological monitor has a sensor port configured to attach and communicate with a sensor. A processor board is in communications with the sensor port and has a board digital signal processor (DSP). Firmware residing on the processor board is executable by the board DSP so as to calculate physiological parameters in response to a sensor signal received from the sensor. Upgrade tools are individually attachable to the sensor port in lieu of the sensor so as to designate to the processor board which of the physiological parameters, if any, to calculate when the sensor is attached to the sensor port.

Abstract: A bio-signal measuring apparatus includes: a substrate; a pulse wave measurer provided at the substrate and configured to measure pulse waves of a subject; and a pressure measurer provided at the substrate and configured to measure a contact pressure between the subject and the pulse wave measurer.