Abstract: Systems, methods, and devices relating to a sensor array for use with a user's finger segment and which indirectly maps the topography of a surface under the finger segment. Each sensor array is worn on a user's finger segment and has multiple sensitive strain gauges as well a positioning sensor. The multiple strain gauges are deployed around the periphery or sides of the finger segment. Each strain gauge measures the deformation of the finger segment pad as the finger segment passes over the surface topography. The relative ratios of the deformation detected indicates the location of a feature or contact point on the topography relative to the group of strain gauges. The positioning sensor determines the array's orientation as well as its location relative to a predetermined global reference frame.

Abstract: An endoscope apparatus measures a subject using a pattern projection image of the subject on which a light and dark pattern of light is projected. The endoscope apparatus includes an insertion tube having a central axis, an image sensor, an objective optical system configured to form an image of the subject on the image sensor, an illumination light source, a pattern projector configured to project the light and dark pattern onto the subject, a projection window for the pattern projector, and an observation window for the objective optical system. The objective optical system has a prism configured to direct light incident through the observation window to a direction toward the image sensor, and the objective optical system is disposed such that an optical axis of the light directed by the prism and incident on the image sensor is offset relative to the central axis of the insertion tube.

Abstract: A medical device capable of determining its location is provided. The medical device comprises a memory, one or more antennas, one or more processors coupled with the memory and the one or more antennas, a location manager component executable by the one or more processors. The location manager component is configured to receive first location information from a first location information source and second location information from a second location information source, to rank the first location information source and the second location information source according to a hierarchy of location information sources, the hierarchy of location information sources specifying that the first location information source is of higher rank than the second location information source, determine an approximate location of the medical device based on the first location information, and improve the accuracy of the approximate location based on the second location information.

Abstract: Described are apparatuses (e.g., devices, systems, software), and methods for monitoring the cardiac health of a patient which incorporates secondary information. The apparatus may be a heart rate monitor, a blood pressure monitor, an ECG or other biometric device in communication with an electronic device having communication ability. The devices detect a cardiac or other biometric measurement and correlate the detected information with secondary information, such as GPS data, to produce a contextualized measurement.

Abstract: A thermal tag for activity monitoring. The thermal tag includes a base layer having a plurality of metal lines to provide a conductive path, and a pattern layer having one or more infrared emitting features positioned over portions of the conductive path, wherein at least one infrared emitting feature couples to the conductive path to emit a predetermined infrared pattern in accordance with nearby activity.

Abstract: At least one exemplary embodiment is directed to a method of generating a hearing impairment compensation function to process audio reproduced by an earphone device. The compensation function includes processing the audio to compensate for frequency sensitivity to improve speech intelligibility.

Abstract: An optimization system for testing a patient's hearing comprising a controller, right and left ear pieces, and a memory. The controller is configured to provide a series of tones to the right and left ear pieces and receive feedback from the patient between each tone provided, indicating that the respective tone was detected in one of the right ear piece and the left ear piece or that the respective tone was not detected. The controller is configured to also generate a data point on an audiogram after receiving each feedback and, after each data point is generated, compute a statistical distribution based on the generated data points, wherein the statistical distribution includes a lowest confidence level. A subsequent tone is selected, each subsequent tone provided in the series of tones being a tone represented at the lowest confidence level in statistical distribution at the time of selection.

Abstract: Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts , on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes , on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: A transdermal and/or intradermal diagnostic device comprising a combined hollow microneedle interstitial fluid (IF) extraction device and a detector can monitor biomarkers in-situ. For example, electrode transducers with optimally arrayed and designed microneedles can be combined with a suitable pumping method to determine biomarker levels in human subjects under intense physical exertion to monitor metabolic stress and fatigue. The device can perform real-time, in-situ measurements of lactate in human subjects. Monitoring of other biomarkers is straightforward.

Abstract: Embodiments of the invention provide analyte sensors having optimized electrodes and/or configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.

Abstract: A personal hand-held monitor (PHHM) comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, wherein the signal acquisition device comprises a blood photosensor having one or more photo-emitters for transmitting light to a body part of a user, one or more photo-detectors for detecting light transmitted through or scattered by the body part and two or more optical cells, at least one of which contains an analyte to be detected or which mimics the absorption spectrum of the analyte to be detected, through which the light that has been or will be transmitted through or scattered by the body part passes before it reaches the or each photo-detector, wherein the processor of the PHHM is adapted to process the signals received from the or each photo-detector to calculate the difference in intensity of light which has passed through the or each analyte cell and light which has passed through the or each non-analyte cell an

Abstract: A system for use in monitoring one or more parameters of a subject's body is described. The system comprising: an illumination unit configured for providing pulsed coherent illumination and directing said illumination onto an inspected region on said subject's body; a collection unit configured for collecting light returning from said inspection region and generate a plurality of data pieces associated with secondary speckle patterns in said light; an external field stimulation unit configured for selectively generating external field stimulation onto the subject's body; and a control unit. The control unit is configured and operable for operating said illumination unit said collection unit and said external field stimulation unit and for receiving said plurality of data pieces from said collection unit to thereby determine said one or more conditions of the subject's body.

Abstract: The disclosure relates to a method and system for controlling glucose levels comprising receiving behavioral sensor measurements and analyte sensor measurements, determining a plurality of analyte profiles from continuous analyte sensor measurements; grouping the plurality of analyte profiles into clusters; assigning a selected behavioral parameter or a selected pattern of behavioral parameters to each analyte profile in a first cluster, and providing a treatment recommendation.

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

Abstract: A concentration measurement apparatus includes a probe being attached to a head and having a light source for outputting measurement light and a photodetection unit for generating a detection signal according to an intensity of incident light, a calculation unit for performing a calculation of a hemoglobin concentration-related numerical value in the head which varies due to repetition of chest compression on the basis of the detection signal according to the intensity of the measurement light propagated through the inside of the head, and an instruction unit for instructing the calculation unit to start the calculation. The photodetection unit continuously generates the detection signal before the calculation start in the calculation unit. The instruction unit determines the calculation start on the basis of the detection signal.

Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.

Abstract: Devices are provided to automatically access blood from beneath or within skin. These devices include an injector configured to drive a needle into the skin and subsequently to retract the needle from the skin. These devices additionally include a seal to which suction is applied. To drive the needle into the skin, the needle is first driven through the seal, creating at least one hole in the seal. The suction applied to the seal acts to draw blood from the puncture formed in the skin by the needle, through the at least one hole in the seal, and to a sensor, blood storage element, or other payload. These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time while a wearer of a device is sleeping.

Abstract: The laser lancing device in accordance with an exemplary embodiment includes: a main body; a laser resonator located within the main body and configured to generate a laser and output the laser forwards; a beam barrel located in front of the laser resonator and including at least one lens unit fixed therein; a window barrel located in front of the beam barrel and connected to the main body; a cap part connected to the front of the window barrel and brought into contact with an irradiation target area; a fan unit communicating with the cap part and induce flow of air; and a communication pipe of which one end is connected to the fan unit and the other end is connected to the cap part.

Abstract: A biological fluid sampling transfer device adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the biological fluid sampling transfer device is able to separate a plasma portion from a cellular portion. After separation, the biological fluid sampling transfer device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid sampling transfer device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The biological fluid sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.

Abstract: The present invention provides method for the quantitative or qualitive evaluation and ement of the user's cognitive ability, screening and improving pathological neurological ions. This is achieved by integrating and adapting current-in-practice cognitive assessment niques to an augmented/mixed reality system, which presents signals and stimulations in various forms to the user meanwhile recording user's surroundings, performance, and responses. The stimulations enhance users' cognitive functions, and the acquired data are evaluated by statistic methods to generate an evaluation that is more standardized and reflective of user's actual condition than current methods.

Abstract: An interactive school communication system is disclosed. The interactive school communication system dynamically connects guardians of students to teachers, administrators, students, and/or school support staff. Real-time data is provided to one or more electronic devices enabling dynamic individual and group communications between guardians, students, teachers, administrators, and/or school support staff. Behavioral trends of students are monitored and used to determine a current behavioral state of the students. School staff and guardians are notified of changes and trends in student behavior.

Abstract: An interactive guardian communication system is disclosed. The interactive communication system dynamically connects guardians of students to teachers, administrators, students, and/or school support staff. Real-time data is provided to one or more electronic devices enabling dynamic individual and group communications between guardians, students, teachers, administrators, and/or school support staff. Identification and authentication of users within the interactive communication system enables secure data input, secure data access, and secure data output reporting.

Abstract: An interactive student communication system is disclosed. The interactive communication system dynamically connects student to teachers, administrators, guardians, and/or school support staff. Real-time data is provided to one or more electronic devices enabling dynamic individual and group communications between guardians, students, teachers, administrators, and/or school support staff. Student use of school resources and/or school software is dependent on student compliance with predetermined school rules.

Abstract: There is provided a method of indirectly estimating muscle strength ratio, comprising: receiving images and associated body part locations of a target individual, wherein the images depict the target individual performing a first and a second defined movement, identifying first image(s) depicting the first defined movement, and obtaining an associated first set of body part locations, identifying second image(s) depicting the second defined movement, and obtaining an associated second set of body part locations, computing a first image-metric according to the first set of body part locations, computing a second image-metric according to the second set of body part locations, computing an image-parameter according to the first and second image-metrics, and converting the image-parameter to an estimate of a measured-parameter indicative of strength measurement ratio of the target muscle(s) obtained by a dynamometer, according to correlation between image-parameters and measured-parameters obtained based on the

Abstract: A SoC includes an AFE to receive a plurality of differential input channels and generate digitized data corresponding to the channels, and a classification processor configured to receive the digitized data from the AFE. The AFE includes a Dual-Channel Chopper to perform channel multiplexing of two channels while simultaneously chopping the channels, a Dual Channel Charge Recycled-AFE having an Chopper-Stabilized Capacitive-Coupled IA including bias sampling capacitors that store bias values associated with the first and second channels to enable swapping between the channel, and a DC servo loop (DSL) having a reduced setting time based on a reduction in a resistance of the pseudo-PMOS in response to engaging a system reset. The classification processor includes a Frequency-Time Division Multiplexing (FTDM) Feature Extraction (FE) engine and a Dual-Detector Architecture (D2A) classification processor.

Abstract: This disclosure generally relates to stable water isotope labeling followed by detection via MRI (swiMRI), including deuterium MRI (dMRI) and 17O MRI, for visualizing rapidly dividing immune cells within target and/or lymphoid organ/s and/or tissues affected by chronic graft-versus-host disease (cGVHD). Using deuterated water labeling, followed by dMRI, a distinction in deuterium signal was detected in a target organ (e.g. liver) of the cGVHD-affected mice compared to unaffected mice, i.e. syngeneic HSCT recipient mice, where the host and donor are matched, and normal (unmanipulated) mice.

Abstract: The present invention is a near-field microwave sensing modality that uses a single probe combined with a classification algorithm to help in detecting the presence of tumors in the human female breast. The concept employs a near-field resonant probe with an ultra-narrow frequency response. The resonant probe is highly sensitive to the changes in the electromagnetic properties of the breast tissues such that the presence of the tumor is gauged by determining the changes in the magnitude and phase response of the sensor's reflection coefficient. A key feature of our proposed detection concept is the simultaneous sensing of tissue property changes to the two female breasts since the right and left healthy breasts are morphologically and materially identical. Once the probe response is recorded for both breasts, the Principle Component Analysis (PCA) method is employed to emphasize the difference in the probe responses.

Abstract: An apparatus for identifying the level of fetal risk during labor, the apparatus comprising: at least one computer operative to receive input signals indicative of at least fetal heart rate (“FHR”) and maternal uterine activity in a patient, the computer operative (i) to determine baseline FHR variability, FHR accelerations, and FHR decelerations, and (ii) to determine when each of at least (a) FHR, (b) baseline FHR variability, (c) FHR accelerations, (d) FHR decelerations, and (e) maternal uterine activity exhibit at least one non-reassuring characteristic from among a plurality of pre-defined non-reassuring characteristics for at least the parameters (a) through (e).

Abstract: An optical system for the detection of skin disease, such as melanoma, acquires images of a lesion on a subject's skin at different wavelengths and utilizes a sweeping arm rotating about the lesion in a clock-like sweep to produce diagnostically relevant metrics and classifiers from the image data so as to enhance detection of the skin disease.

Abstract: The present invention provided a method for diagnosing scoliosis degree using spatial coordinates may include obtaining spatial coordinates corresponding to left, right and center points of shoulders, pelvis and legs of a subject, calculating both height deviations between left and right shoulders and between left and right pelvis, respectively, obtaining a first scoliosis degree by combining the height deviations, calculating a length deviation between the left and right legs, obtaining a second scoliosis degree by the length deviation and, determining a final scoliosis degree by summing the first and second scoliosis degrees.

Abstract: Provided is a respiration analysis system using a gas image detection method, the respiration analysis system including: an exhalation capturing unit provided adjacent to a subject and capturing an image of exhalation exhaled from the mouth and nose of the subject; and a control unit electrically connected to the exhalation capturing unit, and calculating and storing, as data, a respiration cycle and respiration volume from the image captured through the exhalation capturing unit. Accordingly, provided is the respiration analysis system using the gas image detection method, in which not only respiration of the subject is measured in a non-contact manner, but also hypopnea is determined by quantifying volume of the exhalation exhaled by the subject, thereby inferring a disease caused by the hypopnea.

Abstract: A method including a step of preparing a sampling apparatus for use. The sampling apparatus includes a tubular member having an opening on a distal end thereof. An orientation of the distal end of the tubular member is shapeable. The distal end is substantially rigid so as to maintain a manipulated shape after a direct application of a threshold level of force on the distal end of the tubular member. The tubular member also includes a joint member disposed on a proximal end of the tubular member. The joint member is configured to connect the tubular member to a systemic biomarker sampling device.

Abstract: A finger probe for acquiring physiological signals of a subject, the finger probe including a housing and a body portion, the body portion configured to hold therein the housing in a liquid tight manner, wherein the body portion includes a strap configured to secure the finger probe to the subject's finger, a longitudinal groove configured to accommodate the subject's finger, and a hood configured to cover the distal end of the subject's finger from an opposite side thereof, and wherein the housing includes a Printed Circuit Board, a PPG sensor and at least one additional sensor.

Abstract: Systems, methods, and devices provide alarms and alerts in an on-body networked diabetes management system. Methods may include receiving glucose sensor data from a continuous glucose monitor and determining a dosage of insulin delivery based at least in part on the glucose sensor data. The method may include detecting an alarm or alert condition, and sending a wireless communication regarding the alarm or alert condition to a remote user-interface device. The method may include triggering an audible, visual, or haptic alarm or alert on the insulin delivery device unless an acknowledgement of the alarm or alert condition is received within a predetermined period of time.

Abstract: A method of measuring efficacy of treatment of multiple sclerosis (MS) in an animal in a vivarium is described. Animal activity data is collected at multiple times during the night. Sequential time regions of the night are identified as high-activity, activity-drop, or low-activity regions. Embodiments are described to quantify a drop, during the night, of an animal's activity level. These quantified activity-drop scalars for consecutive nights are accumulated in an animal health dataset. This dataset is compared to healthy animals or a standard of care to determine efficacy. One embodiment quantifies an activity-drop by fitting straight-line curves through the data in the three nightly regions. Another embodiment uses a Fourier transform on a circle and a linear combination. Another embodiment compares areas under data curves in the regions. Animals may be housed in cages with other animals.

Abstract: A patient monitoring device, system and method, based on a neck mounted monitoring harness configured to be capable of operating in a stand-alone mode. The neck-mounted harness is a rigid or semi-rigid U-shaped device, with its own independent processor, power source, and ECG circuitry, configured to be worn around the patient's neck with ECG electrodes, mounted on opposite ends of the U, configured to straddle opposite sides of the patient's sternum near the patient's heart. The device is also configured to interface with other devices such as patient ear worn oximeters and oscillometric blood pressure monitors. The device processor has the capability of independently operating the sensors, analyzing sensor data, and reporting results. The device is also configured to interface with various types of external computerized devices. The device can be configured to help to prepare patients for cardiac CT scans or other imaging scans, and this application is described in detail.

Abstract: A sensor cartridge according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor. Certain embodiments of the sensor cartridge protect the sensor from damage, such as damage due to repeated use, reduce the need for sensor sanitization, or both. Further, embodiments of the sensor cartridge are positionable on the user before insertion in the sensor and allow for improved alignment of the treatment site with the sensor. In addition, the sensor cartridge of certain embodiments of the disclosure can be configured to allow a single sensor to comfortably accommodate treatment sites of various sizes such as for both adult and pediatric applications.

Abstract: The present disclosure relates to intelligent wearable devices, and provides a method and a module for detecting a wearing state, and a wearable device thereof. The method for detecting a wearing state is applied to the wearable device, and the wearable device includes a light emitter and a light receiver. The detection method includes: controlling the light emitter to emit at least two types of light signals to a user; controlling the light receiver to receive reflected light corresponding to the at least two types of light signals reflected by the user; and determining the wearing state of the wearable device according to change trends of at least two types of the received reflected light. The wearing state of the wearable device is determined more accurately by adopting embodiments of the present disclosure.

Abstract: An electronic apparatus includes an output interface and a controller. The output interface is configured to output a signal on the basis of scattered light from a measured part. The controller is configured to calculate a temporal change of a power spectrum on the basis of the signal and detect noise included in the signal on the basis of the temporal change of the power spectrum.

Abstract: It is preferable to provide technologies for enabling users to control their internal states more easily, There is provided an output control device including: an output control unit (313) configured to control output of output information in accordance with a change in a state point in a physiological index space corresponding to a physiological index value based on biosensors (230 and 330).

Abstract: Methods and systems for managing at least one chronic disease in a population of patients by collecting information from the population of patients and prescribing courses of medical action based on collaboration between human beings and artificial intelligence (AI). Sensors are placed within the human bodies of the population of patients to continuously sense and monitor at least one physiological parameter and generate data corresponding to the physiological parameter, and the data are transmitted via the Internet and stored in a database. Artificial intelligence is then used to prescribe a course of medical action in an individual patient if the data indicates a medical condition that is within the database and known by the artificial intelligence. The artificial intelligence is also used to request an individualized course of medical action from a medical provider if the data indicates a medical condition not within the database or known by the artificial intelligence.

Abstract: An approach is described with respect to functional age analysis. A method pertaining to such approach may include receiving sensor data collected on a plurality of individuals via a plurality of sensor devices. The method further may include constructing an age indices model by applying machine learning to the collected sensor data. The method further may include determining one or more functional age indices for a subject individual by applying the age indices model to profile data associated with the subject individual. In an embodiment, the method further may include transmitting the one or more functional age indices determined for the subject individual to a professional or a knowledge base, and receiving and processing one or more prescribed recommendations for the subject individual. According to such embodiment, the method further may include updating the age indices model based upon feedback received with respect to the one or more prescribed recommendations.

Abstract: System and methods for detecting precursors of VAP in a patient being ventilated. An exemplary method comprises obtaining a baseline value for a content of a particular VOC in tVOCs in exhaled breath of the patient being ventilated, trending changes of values of the content of the particular VOC in the tVOCs measured at various points of time after ventilation compared to the baseline value, determining whether the patient has potentially infected VAP based at least in part on the trending, and in response to determining that the patient has potentially infected the VAP, generating an alert.

Abstract: An event prediction system according to an aspect includes an acquisition unit and a symptom detection unit. The acquisition unit acquires body movement data about a subject's body movement from a measuring device that outputs the body movement data. The symptom detection unit makes, based on a subset, acquired during a past reference period, of the body movement data, a decision about whether or not there are any symptoms of an onset of a particular event related to the subject.

Abstract: Automated critical congenital heart defect (“CCHD”) screening systems and processes are described. A caregiver may be guided to use a single or dual sensor pulse oximeter to obtain pre- and post-ductal blood oxygenation measurements. A delta of the measurements indicates the possible existence or nonexistence of a CCHD. Errors in the measurements are reduced by a configurable measurement confidence threshold based on, for example, a perfusion index. Measurement data may be stored and retrieved from a remote data processing center for repeated screenings.

Abstract: A device for generating alerts for Hypo and Hyperglycemia Prevention from Continuous Glucose Monitoring (CGM) determines a dynamic risk based on both information of glucose level and a trend obtainable from a CGM signals. The device includes a display whose color depends on the DR (for example, red for high DR, green for low risk). When DR exceeds a certain threshold, alerts are generated to suggest the patient to pay attention to the current glucose reading and to its trend, both of which are shown on the display in numbers and symbols (e.g. an arrow with different slope or color).

Abstract: A method for graphically displaying evoked potentials is disclosed herein. The method transforms each of an averaged evoked potentials into a single vertical line, wherein a first amplitude range is represented by a first color, a second amplitude range is represented by a second color, a third amplitude range is represented by a third color and a fourth amplitude range is represented by a fourth color.

Abstract: The present disclosure provides an electronic device and an alarm control method. The electronic device includes: a detecting component, configured to obtain a physiological feature parameter of a user; a first input component, configured to receive verification information inputted by the user; and a first processing component, configured to receive the inputted verification information via the first input component when determining that the physiological feature parameter obtained by the detecting component satisfies a presupposed condition, perform a normal operating mode of the electronic device when determining that the verification information is first preset verification information, and perform an alarm operation when determining that the verification information is second preset verification information. The alarm operation at least includes transmitting first prestored information to a first object.

Abstract: To provide an exercise support apparatus that can offer safer exercise to be taken during blood purification treatment.